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Validation Study: Response-Predictive Gene Expression Profiling of Glioma Progenitor Cells In Vitro

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Moeckel, Sylvia ; Vollmann-Zwerenz, Arabel ; Proescholdt, Martin A. ; Brawanski, Alexander ; Riemenschneider, Markus J. ; Bogdahn, Ulrich ; Bosserhoff, A. K. ; Spang, Rainer ; Hau, Peter
Date of publication of this fulltext: 29 Mar 2016 07:27


Background In a previous publication we introduced a novel approach to identify genes that hold predictive information about treatment outcome. A linear regression model was fitted by using the least angle regression algorithm (LARS) with the expression profiles of a construction set of 18 glioma progenitor cells enhanced for brain tumor initiating cells (BTIC) before and after in vitro treatment ...


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