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Evolutionary Pareto-optimization of stably folding peptides

Gronwald, Wolfram, Hohm, T. and Hoffmann, D. (2008) Evolutionary Pareto-optimization of stably folding peptides. BMC Bioinformatics 9, p. 109.

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Date of publication of this fulltext: 11 Apr 2016 13:08

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Other URL: http://bmcbioinformatics.biomedcentral.com/articles/10.1186/1471-2105-9-109


Abstract

Background As a rule, peptides are more flexible and unstructured than proteins with their substantial stabilizing hydrophobic cores. Nevertheless, a few stably folding peptides have been discovered. This raises the question whether there may be more such peptides that are unknown as yet. These molecules could be helpful in basic research and medicine. Results As a method to explore the space of ...

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Item type:Article
Date:February 2008
Institutions:Medicine > Institut für Funktionelle Genomik > Lehrstuhl für Funktionelle Genomik (Prof. Oefner)
Identification Number:
ValueType
10.1186/1471-2105-9-109DOI
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:33611
Owner only: item control page

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