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Slug Is Increased in Vascular Remodeling and Induces a Smooth Muscle Cell Proliferative Phenotype

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Coll-Bonfill, N. ; Peinado, V. I. ; Pisano, M. V. ; Parrizas, M. ; Blanco, I. ; Evers, Maurits ; Engelmann, Julia C. ; Garcia-Lucio, J. ; Tura-Ceide, O. ; Meister, Gunter ; Barbera, J. A. ; Musri, M. M.
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Date of publication of this fulltext: 09 Aug 2016 12:39


Objective Previous studies have confirmed Slug as a key player in regulating phenotypic changes in several cell models, however, its role in smooth muscle cells (SMC) has never been assessed. The purpose of this study was to evaluate the expression of Slug during the phenotypic switch of SMC in vitro and throughout the development of vascular remodeling. Methods and Results Slug expression was ...


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