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Non-transcriptional pathway features reconstructed from secondary effects of RNA interference

Markowetz, F., Bloch, J. and Spang, Rainer (2005) Non-transcriptional pathway features reconstructed from secondary effects of RNA interference. Bioinformatics 21 (21), pp. 4026-4032.

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Other URL: http://bioinformatics.oxfordjournals.org/content/21/21/4026.long


Abstract

Motivation: Cellular signaling pathways, which are not modulated on a transcriptional level, cannot be directly deduced from expression profiling experiments. The situation changes, when external interventions such as RNA interference or gene knock-outs come into play. Even if the expression of the signaling genes is not changed, secondary effects in downstream genes shed light on the pathway, ...

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Item type:Article
Date:1 November 2005
Institutions:Medicine > Institut für Funktionelle Genomik > Lehrstuhl für Statistische Bioinformatik (Prof. Spang)
Identification Number:
ValueType
16159925PubMed ID
10.1093/bioinformatics/bti662DOI
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:No
Item ID:34392
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