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Finding disease specific alterations in the co-expression of genes

Kostka, Dennis ; Spang, Rainer


MOTIVATION: Standard analysis routines for microarray data aim at differentially expressed genes. In this paper, we address the complementary problem of detecting sets of differentially co-expressed genes in two phenotypically distinct sets of expression profiles. RESULTS: We introduce a score for differential co-expression and suggest a computationally efficient algorithm for finding high ...


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