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Genomic organization of the human tissue inhibitor of metalloproteinases-3 (TIMP3)

Stöhr, H, Roomp, K, Felbor, U and Weber, Bernhard H. F. (1995) Genomic organization of the human tissue inhibitor of metalloproteinases-3 (TIMP3). Genome research 5 (5), pp. 483-487.

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Abstract

The tissue inhibitors of metalloproteinases (TIMPs) play a crucial role in the physiological turnover of the extracellular matrix (ECM) by tightly regulating matrix metalloproteinase (MMP) activities. Disturbances in the TIMP/MMP system have been implicated in many disease processes where loss of ECM integrity is a principal feature. More recently, we have shown that mutations in TIMP3 cause the ...

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Item type:Article
Date:1995
Institutions:Medicine > Lehrstuhl für Humangenetik
Identification Number:
ValueType
10.1101/gr.5.5.483DOI
8808469PubMed ID
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:No
Item ID:35465
Owner only: item control page

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