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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-354659
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.35465
Zusammenfassung
The tissue inhibitors of metalloproteinases (TIMPs) play a crucial role in the physiological turnover of the extracellular matrix (ECM) by tightly regulating matrix metalloproteinase (MMP) activities. Disturbances in the TIMP/MMP system have been implicated in many disease processes where loss of ECM integrity is a principal feature. More recently, we have shown that mutations in TIMP3 cause the ...
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