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Mitochondriale Adaptationen in der progressiven Herzinsuffizienz und nach kombinierter RAS/NEP-Inhibition

Grois, Laura (2017) Mitochondriale Adaptationen in der progressiven Herzinsuffizienz und nach kombinierter RAS/NEP-Inhibition. PhD, Universität Regensburg.

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Date of publication of this fulltext: 09 Oct 2017 13:44

Abstract (German)

Trotz der zentralen Rolle energetischer Prozesse in der Herzinsuffizienz sind die mitochondrialen Adaptationen noch immer unzureichend charakterisiert. Daher war es das Ziel dieser Arbeit, die mitochondrialen Veränderungen in der progressiven Herzinsuffizienz zu charakterisieren und den Einfluss einer RAAS-/NEP-Inhibition auf Proteomebene zu untersuchen. Die Untersuchungen dieser Arbeit konnten ...

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Translation of the abstract (English)

Despite the central role of energetic processes in heart failure, mitochondrial adaptations are still inadequately characterized. Therefore, the aim of this work was to characterize mitochondrial changes in progressive heart failure and to investigate the influence of RAAS / NEP inhibition on the proteome level in rabbits. The results demonstrate significant changes in the expression of numerous ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:9 October 2017
Referee:PD Dr. Christoph Birner and Prof. Dr. Frank Schweda
Date of exam:9 October 2017
Institutions:Medicine > Lehrstuhl für Innere Medizin II
Keywords:Herzinsuffizienz, Mitochondrium, RAS/NEP-Inhibition, Therapie Herzinsuffizienz
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:36222
Owner only: item control page

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