| License: Creative Commons Attribution 4.0 (6MB) |
- URN to cite this document:
- urn:nbn:de:bvb:355-epub-373286
- DOI to cite this document:
- 10.5283/epub.37328
Abstract
The 18 kDa translocator protein (TSPO) is an evolutionary conserved cholesterol binding protein localized in the outer mitochondrial membrane. Expression of TSPO is upregulated in activated microglia in various neuroinflammatory, neurodegenerative, and neoplastic disorders. Therefore, TSPO radioligands are used as biomarkers in positron emission tomography (PET) studies. In particular, a common ...
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