A Balanced Risk-Benefit Analysis to Determine Human Risks Associated with Pyrrolizidine Alkaloids (PA)—The Case of Herbal Medicinal Products Containing St. John’s Wort Extracts (SJW)

• URN zum Zitieren dieses Dokuments: urn:nbn:de:bvb:355-epub-374238

Habs, Michael, Binder, Karin , Krauss, Stefan, Müller, Karolina, Ernst, Brigitte, Valentini, Luzia und Koller, Michael (2018) A Balanced Risk-Benefit Analysis to Determine Human Risks Associated with Pyrrolizidine Alkaloids (PA)—The Case of Herbal Medicinal Products Containing St. John’s Wort Extracts (SJW). Nutrients 10 (7), S. 804.

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Andere URL zum Volltext: http://doi.org/10.3390/nu10070804, http://www.mdpi.com/2072-6643/10/7/804

Zusammenfassung

Objectives: Pyrrolizidine alkaloids (PA) exist ubiquitously in our environment. More than 6000 plants, about 3% of the world’s flowering plants, are known to synthesize PA. As a consequence, many herbal ingredients, including St. John’s wort (SJW), are contaminated with PA that can possess acute and subchronic toxic effects as well as mutagenic and genotoxic properties. Therefore, the possible ...

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