Go to content
UR Home

A Balanced Risk-Benefit Analysis to Determine Human Risks Associated with Pyrrolizidine Alkaloids (PA)—The Case of Herbal Medicinal Products Containing St. John’s Wort Extracts (SJW)

URN to cite this document:
DOI to cite this document:
Habs, Michael ; Binder, Karin ; Krauss, Stefan ; Müller, Karolina ; Ernst, Brigitte ; Valentini, Luzia ; Koller, Michael
License: Creative Commons Attribution 4.0
(1MB) - Repository staff only
Date of publication of this fulltext: 25 Jun 2018 13:28


Objectives: Pyrrolizidine alkaloids (PA) exist ubiquitously in our environment. More than 6000 plants, about 3% of the world’s flowering plants, are known to synthesize PA. As a consequence, many herbal ingredients, including St. John’s wort (SJW), are contaminated with PA that can possess acute and subchronic toxic effects as well as mutagenic and genotoxic properties. Therefore, the possible ...


Owner only: item control page
  1. Homepage UR

University Library

Publication Server


Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons