Winkler, Thomas W, Günther, Felix, Höllerer, Simon, Zimmermann, Martina, Loos, Ruth JF, Kutalik, Zoltán and Heid, Iris M (2018) A joint view on genetic variants for adiposity differentiates subtypes with distinct metabolic implications. Nature Communications 9 (1946), pp. 1-13.
| License: Creative Commons Attribution 4.0 Download (1MB) |
Other URL: http://doi.org/10.1038/s41467-018-04124-9, https://www.nature.com/articles/s41467-018-04124-9
Abstract
The problem of the genetics of related phenotypes is often addressed by analyzing adjusted-model traits, but such traits warrant cautious interpretation. Here, we adopt a joint view of adiposity traits in ~322,154 subjects (GIANT consortium). We classify 159 signals associated with body mass index (BMI), waist-to-hip ratio (WHR), or WHR adjusted for BMI (WHRadjBMI) at P < 5 × 10−8, into four ...
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| Item type: | Article | ||||
|---|---|---|---|---|---|
| Date: | 16 May 2018 | ||||
| Institutions: | Medicine > Institut für Epidemiologie und Präventivmedizin > Lehrstuhl für Genetische Epidemiologie | ||||
| Projects: | Open Access Publizieren (DFG) | ||||
| Identification Number: |
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| Dewey Decimal Classification: | 600 Technology > 610 Medical sciences Medicine | ||||
| Status: | Published | ||||
| Refereed: | Yes, this version has been refereed | ||||
| Created at the University of Regensburg: | Yes | ||||
| Item ID: | 37428 |
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