Go to content
UR Home

Integrated analysis of epigenetic and genetic changes during MDS progression

Pohl, Sandra (2019) Integrated analysis of epigenetic and genetic changes during MDS progression. PhD, Universität Regensburg.

[img]License: Creative Commons Attribution 4.0
PDF
Download (11MB)
Date of publication of this fulltext: 08 Aug 2019 07:19

Abstract (English)

DNA methylation is important during development of vertebrate organisms as well as for sustaining genome integrity and gene expression. Alterations of DNA methylation patterns are often associated with different diseases, for instance myelodysplastic syndromes (MDS) or acute myeloid leukemia (AML). Consequences of aberrant DNA methylation are the silencing of tumor suppressor genes due to ...

plus

Translation of the abstract (German)

DNA‐Methylierung ist ein wichtiger Prozess bei der Entwicklung von Organismen und spielt ebenfalls eine wichtige Rolle bei der Aufrechterhaltung der genomischen Integrität sowie der Genexpression. Eine Assoziation von Veränderungen im DNA-Methylierungsmuster konnte für verschiedene Erkrankungen festgestellt werden, unter anderen bei den myelodysplastischen Syndromen (MDS) und der akuten ...

plus


Export bibliographical data



Item type:Thesis of the University of Regensburg (PhD)
Date:8 August 2019
Referee:Prof. Dr. Michael Rehli
Date of exam:8 August 2018
Institutions:Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie
Keywords:Epigenetics, DNA methylation, Myelodysplastic syndromes
Dewey Decimal Classification:500 Science > 570 Life sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:37599
Owner only: item control page

Downloads

Downloads per month over past year

  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de

Dissertations: dissertationen@ur.de

Research data: daten@ur.de

Contact persons