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Functional characterization of the cell polarity proteins Bazooka and LKB1

Kullmann, Lars (2018) Functional characterization of the cell polarity proteins Bazooka and LKB1. PhD, Universität Regensburg.

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Date of publication of this fulltext: 12 Nov 2018 10:26

Abstract (English)

Cell polarity is a highly conserved characteristic of epithelia. Baz and LKB1 are two key players in the establishment of a cellular polarity and the role of their membrane localization and organization were the subjects of this study. The liver kinase B1 (LKB1) is an essential kinase that regulates various cellular processes by modulating the activity of several downstream kinases. Its loss or ...

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Translation of the abstract (German)

Zellpolarität ist eine hochkonservierte Eigenschaft von Epithelzellen. Bazooka (Baz) und die Liver Kinase B1 (LKB1) sind zwei Schlüsselproteine bei der Etablierung einer zellulären Polarität und die Rolle ihrer Membranlokalisierung und -organisation waren die Themen dieser Studie. LKB1 ist eine essentielle Kinase, die verschiedene Zellprozesse reguliert, indem sie die Aktivität mehrerer Kinasen ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:October 2018
Referee:Prof. Dr. Dr. Michael Krahn
Date of exam:9 October 2018
Institutions:Biology, Preclinical Medicine > Institut für Anatomie > Lehrstuhl für Molekulare und zelluläre Anatomie > Prof. Dr. Ralph Witzgall
Keywords:Zellpolarität, Bazooka, LKB1
Dewey Decimal Classification:500 Science > 570 Life sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:37916
Owner only: item control page

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