Anzahl der Einträge in dieser Kategorie: 76.
2023
Jiménez-Moreno, Natalia,
Kollareddy, Madhu,
Stathakos, Petros,
Moss, Joanna J.,
Antón, Zuriñe,
Shoemark, Deborah K.,
Sessions, Richard B.,
Witzgall, Ralph ,
Caldwell, Maeve und
Lane, Jon D.
(2023)
ATG8-dependent LMX1B-autophagy crosstalk shapes human midbrain dopaminergic neuronal resilience.
Journal of Cell Biology 222 (5), e201910133.
2022
Heinl, Elena-Sofia,
Lorenz, Sebastian,
Schmidt, Barbara ,
Laqtom, Nouf Nasser M.,
Mazzulli, Joseph R.,
Francelle, Laetitia ,
Yu, Timothy W.,
Greenberg, Benjamin ,
Storch, Stephan,
Tegtmeier, Ines,
Othmen, Helga,
Maurer, Katja,
Steinfurth, Malin,
Witzgall, Ralph,
Milenkovic, Vladimir M.,
Wetzel, Christian H. und
Reichold, Markus
(2022)
CLN7/MFSD8 may be an important factor for SARS-CoV-2 cell entry.
iScience 25 (10), S. 105082.
Issler, Naomi,
Afonso, Sara,
Weissman, Irith,
Jordan, Katrin,
Cebrian-Serrano, Alberto,
Meindl, Katrin,
Dahlke, Eileen,
Tziridis, Konstantin,
Yan, Guanhua,
Robles-López, José M.,
Tabernero, Lydia ,
Patel, Vaksha,
Kesselheim, Anne,
Klootwijk, Enriko D.,
Stanescu, Horia C.,
Dumitriu, Simona,
Iancu, Daniela,
Tekman, Mehmet,
Mozere, Monika,
Jaureguiberry, Graciana,
Outtandy, Priya,
Russell, Claire,
Forst, Anna-Lena,
Sterner, Christina,
Heinl, Elena-Sofia,
Othmen, Helga,
Tegtmeier, Ines,
Reichold, Markus,
Schiessl, Ina Maria ,
Limm, Katharina,
Oefner, Peter,
Witzgall, Ralph,
Fu, Lifei,
Theilig, Franziska,
Schilling, Achim,
Shuster Biton, Efrat,
Kalfon, Limor,
Fedida, Ayalla,
Arnon-Sheleg, Elite,
Ben Izhak, Ofer,
Magen, Daniella,
Anikster, Yair,
Schulze, Holger,
Ziegler, Christine,
Lowe, Martin,
Davies, Benjamin,
Böckenhauer, Detlef,
Kleta, Robert,
Falik Zaccai, Tzipora C. und
Warth, Richard
(2022)
A Founder Mutation in EHD1 Presents with Tubular Proteinuria and Deafness.
Journal of the American Society of Nephrology 33 (4), S. 732-745.
Issler, Naomi,
Afonso, Sara Cerqueira,
Weissman, Irith,
Jordan, Katrin,
Cebrian-Serrano, Alberto,
Meindl, Katrin,
Dahlke, Eileen,
Tziridis, Konstantin,
Yan, Guanhua,
Robles-López, José M.,
Tabernero, Lydia ,
Patel, Vaksha,
Kesselheim, Anne,
Klootwijk, Enriko D.,
Stanescu, Horia C.,
Dumitriu, Simona,
Iancu, Daniela,
Tekman, Mehmet,
Mozere, Monika,
Jaureguiberry, Graciana,
Outtandy, Priya,
Russell, Claire,
Forst, Anna-Lena,
Sterner, Christina,
Heinl, Elena-Sofia,
Othmen, Helga,
Tegtmeier, Ines,
Reichold, Markus,
Schiessl, Ina Maria ,
Limm, Katharina,
Oefner, Peter J.,
Witzgall, Ralph,
Fu, Lifei,
Theilig, Franziska,
Schilling, Achim,
Shuster Biton, Efrat,
Kalfon, Limor,
Fedida, Ayalla,
Arnon-Sheleg, Elite,
Ben Izhak, Ofer,
Magen, Daniella,
Anikster, Yair,
Schulze, Holger,
Ziegler, Christine,
Lowe, Martin,
Davies, Benjamin,
Böckenhauer, Detlef,
Kleta, Robert,
Falik Zaccai, Tzipora C. und
Warth, Richard
(2022)
A Founder Mutation in EHD1 Presents with Tubular Proteinuria and Deafness.
Nicht ausgewählt, Universität Regensburg.
Volltext nicht vorhanden.
2021
Grosch, Melanie,
Brunner, Katrin,
Ilyaskin, Alexandr V. ,
Schober, Michael,
Staudner, Tobias,
Schmied, Denise,
Stumpp, Tina,
Schmidt, Kerstin N.,
Madej, M. Gregor ,
Pessoa, Thaissa D.,
Othmen, Helga,
Kubitza, Marion,
Osten, Larissa,
de Vries, Uwe,
Mair, Magdalena M. ,
Somlo, Stefan,
Moser, Markus,
Kunzelmann, Karl,
Ziegler, Christine ,
Haerteis, Silke,
Korbmacher, Christoph und
Witzgall, Ralph
(2021)
A polycystin-2 protein with modified channel properties leads to an increased diameter of renal tubules and to renal cysts.
Journal of Cell Science 134 (16).
Volltext nicht vorhanden.
2020
Maslanka Figueroa, Sara ,
Fleischmann, Daniel,
Beck, Sebastian,
Tauber, Philipp,
Witzgall, Ralph,
Schweda, Frank und
Goepferich, Achim
(2020)
Nanoparticles Mimicking Viral Cell Recognition Strategies Are Superior Transporters into Mesangial Cells.
Advanced Science 7 (11), S. 1903204.
Fleischmann, Daniel,
Maslanka-Figueroa, Sara,
Beck, Sebastian,
Abstiens, Kathrin,
Witzgall, Ralph,
Schweda, Frank,
Tauber, Philipp und
Goepferich, Achim
(2020)
Adenovirus-Mimetic Nanoparticles: Sequential Ligand-Receptor Interplay as a Universal Tool for Enhanced In Vitro/In Vivo Cell Identification.
ACS Applied Materials & Interfaces 12 (31), S. 34689-34702.
Volltext nicht vorhanden.
Rachel, Reinhard,
Walther, Paul,
Maaßen, Christine,
Daberkow, Ingo,
Matsuoka, Masahiro und
Witzgall, Ralph
(2020)
Dual-axis STEM tomography at 200 kV: Setup, performance, limitations.
Journal of Structural Biology 211 (3), S. 107551.
Volltext nicht vorhanden.
2018
Billot, Katy,
Coquil, Charlène,
Villiers, Benoit,
Josselin-Foll, Béatrice,
Desban, Nathalie,
Delehouzé, Claire,
Oumata, Nassima,
Le Meur, Yannick ,
Boletta, Alessandra,
Weimbs, Thomas ,
Grosch, Melanie,
Witzgall, Ralph,
Saunier, Sophie ,
Fischer, Evelyne,
Pontoglio, Marco,
Fautrel, Alain,
Mrug, Michal,
Wallace, Darren,
Tran, Pamela V.,
Trudel, Marie,
Bukanov, Nikolay,
Ibraghimov-Beskrovnaya, Oxana und
Meijer, Laurent
(2018)
Casein kinase 1ε and 1α as novel players in polycystic kidney disease and mechanistic targets for (R)-roscovitine and (S)-CR8.
American Journal of Physiology-Renal Physiology 315 (1), F57-F73.
Volltext nicht vorhanden.
Reichold, Markus,
Klootwijk, Enriko D.,
Reinders, Joerg,
Otto, Edgar A.,
Milani, Mario ,
Broeker, Carsten,
Laing, Chris,
Wiesner, Julia,
Devi, Sulochana,
Zhou, Weibin,
Schmitt, Roland,
Tegtmeier, Ines,
Sterner, Christina,
Doellerer, Hannes,
Renner, Kathrin,
Oefner, Peter J.,
Dettmer, Katja,
Simbuerger, Johann M.,
Witzgall, Ralph,
Stanescu, Horia C.,
Dumitriu, Simona,
Iancu, Daniela,
Patel, Vaksha,
Mozere, Monika,
Tekman, Mehmet ,
Jaureguiberry, Graciana,
Issler, Naomi,
Kesselheim, Anne,
Walsh, Stephen B.,
Gale, Daniel P. ,
Howie, Alexander J.,
Martins, Joana R. ,
Hall, Andrew M.,
Kasgharian, Michael,
O’Brien, Kevin,
Ferreira, Carlos R.,
Atwal, Paldeep S.,
Jain, Mahim,
Hammers, Alexander ,
Charles-Edwards, Geoffrey,
Choe, Chi-Un,
Isbrandt, Dirk,
Cebrian-Serrano, Alberto,
Davies, Ben,
Sandford, Richard N.,
Pugh, Christopher,
Konecki, David S.,
Povey, Sue,
Bockenhauer, Detlef,
Lichter-Konecki, Uta,
Gahl, William A.,
Unwin, Robert J.,
Warth, Richard und
Kleta, Robert
(2018)
Glycine Amidinotransferase (GATM), Renal Fanconi Syndrome, and Kidney Failure.
Journal of the American Society of Nephrology 29 (7), S. 1849-1858.
Volltext nicht vorhanden.
2017
Ciolek, Justyna,
Reinfrank, Helen,
Quinton, Loïc,
Viengchareun, Say,
Stura, Enrico A.,
Vera, Laura,
Sigismeau, Sabrina,
Mouillac, Bernard,
Orcel, Hélène,
Peigneur, Steve,
Tytgat, Jan,
Droctové, Laura,
Beau, Fabrice,
Nevoux, Jerome,
Lombès, Marc ,
Mourier, Gilles,
De Pauw, Edwin ,
Servent, Denis ,
Mendre, Christiane,
Witzgall, Ralph und
Gilles, Nicolas
(2017)
Green mamba peptide targets type-2 vasopressin receptor against polycystic kidney disease.
Proceedings of the National Academy of Sciences 114 (27), S. 7154-7159.
Volltext nicht vorhanden.
Wilkes, Martin,
Madej, M. Gregor ,
Kreuter, Lydia,
Rhinow, Daniel,
Heinz, Veronika,
De Sanctis, Silvia,
Ruppel, Sabine,
Richter, Rebecca M.,
Joos, Friederike,
Grieben, Marina,
Pike, Ashley C. W.,
Huiskonen, Juha T. ,
Carpenter, Elisabeth P.,
Kühlbrandt, Werner ,
Witzgall, Ralph und
Ziegler, Christine
(2017)
Molecular insights into lipid-assisted Ca2+ regulation of the TRP channel Polycystin-2.
Nature Structural & Molecular Biology 24 (2), S. 123-130.
Volltext nicht vorhanden.
2016
2015
Burghardt, Tillmann,
Hochapfel, Florian,
Salecker, Benjamin,
Meese, Christine,
Gröne, Hermann-Josef,
Rachel, Reinhard,
Wanner, Gerhard,
Krahn, Michael P. und
Witzgall, Ralph
(2015)
Advanced electron microscopic techniques provide a deeper insight into the peculiar features of podocytes.
American Journal of Physiology-Renal Physiology 309 (12), F1082-F1089.
Volltext nicht vorhanden.
Dong, Lihua,
Pietsch, Stefan,
Tan, Zenglai,
Perner, Birgit,
Sierig, Ralph,
Kruspe, Dagmar,
Groth, Marco,
Witzgall, Ralph ,
Gröne, Hermann-Josef,
Platzer, Matthias und
Englert, Christoph
(2015)
Integration of Cistromic and Transcriptomic Analyses Identifies Nphs2, Mafb, and Magi2 as Wilms’ Tumor 1 Target Genes in Podocyte Differentiation and Maintenance.
Journal of the American Society of Nephrology 26 (9), S. 2118-2128.
Volltext nicht vorhanden.
2014
2013
Burghardt, Tillmann,
Kastner, Jürgen,
Suleiman, Hani,
Rivera-Milla, Eric,
Stepanova, Natalya,
Lottaz, Claudio,
Kubitza, Marion,
Böger, Carsten A.,
Schmidt, Sarah,
Gorski, Mathias,
de Vries, Uwe,
Schmidt, Helga,
Hertting, Irmgard,
Kopp, Jeffrey ,
Rascle, Anne,
Moser, Markus,
Heid, Iris M.,
Warth, Richard ,
Spang, Rainer,
Wegener, Joachim,
Mierke, Claudia T. ,
Englert, Christoph und
Witzgall, Ralph
(2013)
LMX1B is essential for the maintenance of differentiated podocytes in adult kidneys.
Journal of the American Society of Nephrology : JASN 24 (11), S. 1830-1848.
Volltext nicht vorhanden.
Morick, Daniela,
Schatz, Michaela,
Hubrich, Raphael,
Hoffmeister, Helen,
Krefft, Anya,
Witzgall, Ralph und
Steinem, Claudia
(2013)
Phosphorylation of C-terminal polycystin-2 influences the interaction with PIGEA14: A QCM study based on solid supported membranes.
Biochemical and Biophysical Research Communications 437 (4), S. 532-537.
Volltext nicht vorhanden.
Holzhauser, Carolin,
Kracher, Sabrina,
Rubner, Moritz M.,
Schmucker, Wolfgang,
Wagenknecht, Hans‐Achim und
Witzgall, Ralph
(2013)
Photochemically Active Fluorophore–DNA/RNA Conjugates for Cellular Imaging of Nucleic Acids by Readout in Electron Microscopy.
ChemistryOpen 2 (4), S. 136-140.
Volltext nicht vorhanden.
2012
Parkinson, John,
Ulas, Thomas,
Riemer, S. Alexander,
Zaparty, Melanie,
Siebers, Bettina und
Schomburg, Dietmar
(2012)
Genome-Scale Reconstruction and Analysis of the Metabolic Network in the Hyperthermophilic Archaeon Sulfolobus Solfataricus.
PLoS ONE 7 (8), e43401.
Volltext nicht vorhanden.
Pollinger, Klaus,
Hennig, Robert,
Breunig, Miriam ,
Teßmar, Jörg ,
Ohlmann, Andreas ,
Tamm, Ernst R. ,
Witzgall, Ralph und
Goepferich, Achim
(2012)
Kidney Podocytes as Specific Targets for cyclo(RGDfC)-Modified Nanoparticles.
Small 8, S. 3368-3375.
Volltext nicht vorhanden.
2011
Tian, Yuemin,
Kongsuphol, Patthara,
Hug, Martin,
Ousingsawat, Jiraporn,
Witzgall, Ralph ,
Schreiber, Rainer und
Kunzelmann, Karl
(2011)
Calmodulin‐dependent activation of the epithelial calcium‐dependent chloride channel TMEM16A.
The FASEB Journal 25 (3), S. 1058-1068.
Volltext nicht vorhanden.
Hoffmeister, Helen,
Babinger, Karin,
Gürster, Sonja,
Cedzich, Anna,
Meese, Christine,
Schadendorf, Karin,
Osten, Larissa,
de Vries, Uwe,
Rascle, Anne und
Witzgall, Ralph
(2011)
Polycystin-2 takes different routes to the somatic and ciliary plasma membrane.
Journal of Cell Biology 192 (4), S. 631-645.
Volltext nicht vorhanden.
Kunzelmann, Karl ,
Kongsuphol, Patthara,
Chootip, Krongkarn,
Toledo, Caio,
Martins, Joana R. ,
Almaca, Joana ,
Tian, Yuemin,
Witzgall, Ralph ,
Ousingsawat, Jiraporn und
Schreiber, Rainer
(2011)
Role of the Ca2+-activated Cl- channels bestrophin and anoctamin in epithelial cells.
Biological Chemistry 392 (1-2).
Volltext nicht vorhanden.
2010
Barro-Soria, René,
Aldehni, Fadi,
Almaça, Joana ,
Witzgall, Ralph ,
Schreiber, Rainer und
Kunzelmann, Karl
(2010)
ER-localized bestrophin 1 activates Ca2+-dependent ion channels TMEM16A and SK4 possibly by acting as a counterion channel.
Pflügers Archiv - European Journal of Physiology 459 (3), S. 485-497.
Volltext nicht vorhanden.
Reichold, Markus,
Zdebik, Anselm A.,
Lieberer, Evelyn,
Rapedius, Markus,
Schmidt, Katharina,
Bandulik, Sascha,
Sterner, Christina,
Tegtmeier, Ines,
Penton, David,
Baukrowitz, Thomas,
Hulton, Sally-Anne,
Witzgall, Ralph ,
Ben-Zeev, Bruria,
Howie, Alexander J.,
Kleta, Robert,
Bockenhauer, Detlef und
Warth, Richard
(2010)
KCNJ10 gene mutations causing EAST syndrome (epilepsy, ataxia, sensorineural deafness, and tubulopathy) disrupt channel function.
Proceedings of the National Academy of Sciences 107 (32), S. 14490-14495.
Volltext nicht vorhanden.
Behn, Daniela,
Bosk, Sabine,
Hoffmeister, Helen,
Janshoff, Andreas ,
Witzgall, Ralph und
Steinem, Claudia
(2010)
Quantifying the interaction of the C-terminal regions of polycystin-2 and polycystin-1 attached to a lipid bilayer by means of QCM.
Biophysical Chemistry 150 (1-3), S. 47-53.
Volltext nicht vorhanden.
2009
Schumann, Frank,
Hoffmeister, Helen,
Bader, Reto,
Schmidt, Maren,
Witzgall, Ralph und
Kalbitzer, Hans Robert
(2009)
Ca2+-dependent Conformational Changes in a C-terminal Cytosolic Domain of Polycystin-2.
Journal of Biological Chemistry 284 (36), S. 24372-24383.
Volltext nicht vorhanden.
Osten, Larissa,
Kubitza, Marion,
Gallagher, Anna Rachel,
Kastner, Jürgen,
Olbrich, Heike,
Vries, Uwe,
Kees, Frieder,
Lelongt, Brigitte,
Somlo, Stefan,
Omran, Heymut und
Witzgall, Ralph
(2009)
Doxycycline accelerates renal cyst growth and fibrosis in the pcy/pcy mouse model of type 3 nephronophthisis, a form of recessive polycystic kidney disease.
Histochemistry and Cell Biology 132 (2), S. 199-210.
Volltext nicht vorhanden.
Schumann, Frank H.,
Hoffmeister, Helen,
Schmidt, Maren,
Bader, Reto,
Besl, Elisabeth,
Witzgall, Ralph und
Kalbitzer, Hans Robert
(2009)
NMR-assignments of a cytosolic domain of the C-terminus of polycystin-2.
Biomolecular NMR Assignments 3 (1), S. 141-144.
Volltext nicht vorhanden.
Rascle, Anne,
Neumann, Tanja,
Raschta, Anne-Sarah,
Neumann, Astrid,
Heining, Eva,
Kastner, Juergen und
Witzgall, Ralph
(2009)
The LIM-homeodomain transcription factor LMX1B regulates expression of NF-kappa B target genes.
Experimental Cell Research 315 (1), S. 76-96.
Volltext nicht vorhanden.
2008
Felekkis, Kyriacos N ,
Koupepidou, Panayiota,
Kastanos, Evdokia,
Witzgall, Ralph ,
Bai, Chang-Xi,
Li, Li,
Tsiokas, Leonidas,
Gretz, Norbert und
Deltas, Constantinos
(2008)
Mutant polycystin-2 induces proliferation in primary rat tubular epithelial cells in a STAT-1/p21-independent fashion accompanied instead by alterations in expression of p57KIP2and Cdk2.
BMC Nephrology 9 (1).
Volltext nicht vorhanden.
Aguiari, G.,
Trimi, V.,
Bogo, M.,
Mangolini, A.,
Szabadkai, G.,
Pinton, P. ,
Witzgall, R. ,
Harris, P. C.,
Borea, P. A.,
Rizzuto, R. und
Del Senno, L.
(2008)
Novel role for polycystin‐1 in modulating cell proliferation through calcium oscillations in kidney cells.
Cell Proliferation 41 (3), S. 554-573.
Volltext nicht vorhanden.
2007
Endele, Sabine,
Klein, Sabine,
Richter, Sabine,
Molter, Tina,
Amann, Kerstin,
Klanke, Bernd,
Witzgall, Ralph ,
Johnson, Randy L.,
Hilgers, Karl F. und
Winterpacht, Andreas
(2007)
Renal phenotype in heterozygous Lmx1b knockout mice (Lmx1b +/−) after unilateral nephrectomy.
Transgenic Research 16 (6), S. 723-729.
Volltext nicht vorhanden.
Suleiman, Hani,
Heudobler, Daniel,
Raschta, Anne-Sarah,
Zhao, Yangu,
Zhao, Qi,
Hertting, Irmgard,
Vitzthum, Helga,
Moeller, Marcus J.,
Holzman, Lawrence B.,
Rachel, Reinhard,
Johnson, Randy,
Westphal, Heiner,
Rascle, Anne und
Witzgall, Ralph
(2007)
The podocyte-specific inactivation of Lmx1b, Ldb1 and E2a yields new insight into a transcriptional network in podocytes.
Developmental biology 304 (2), S. 701-712.
Volltext nicht vorhanden.
2006
Gallagher, Anna Rachel,
Hoffmann, Sigrid,
Brown, Nelson,
Cedzich, Anna,
Meruvu, Sujatha,
Podlich, Dirk,
Feng, Yuxi,
Könecke, Vera,
de Vries, Uwe,
Hammes, Hans-Peter,
Gretz, Norbert und
Witzgall, Ralph
(2006)
A Truncated Polycystin-2 Protein Causes Polycystic Kidney Disease and Retinal Degeneration in Transgenic Rats.
Journal of the American Society of Nephrology 17 (10), S. 2719-2730.
Volltext nicht vorhanden.
Banzi, Manuela,
Aguiari, Gianluca,
Trimi, Viky,
Mangolini, Alessandra,
Pinton, Paolo ,
Witzgall, Ralph ,
Rizzuto, Rosario und
Senno, Laura del
(2006)
Polycystin-1 promotes PKCα-mediated NF-κB activation in kidney cells.
Biochemical and Biophysical Research Communications 350 (2), S. 257-262.
Volltext nicht vorhanden.
2005
Karcher, Christina,
Fischer, Anja,
Schweickert, Axel,
Bitzer, Eva,
Horie, Shigeo,
Witzgall, Ralph und
Blum, Martin
(2005)
Lack of a laterality phenotype in Pkd1 knock-out embryos correlates with absence of polycystin-1 in nodal cilia.
Differentiation 73 (8), S. 425-432.
Volltext nicht vorhanden.
Brown, Joanna H.,
Bihoreau, Marie-Thére[Combining Grave Accent]se,
Hoffmann, Sigrid,
Kra[Combining Diaeresis]nzlin, Bettina,
Tychinskaya, Iulia,
Obermu[Combining Diaeresis]ller, Nicholas,
Podlich, Dirk,
Boehn, Suzanne N.,
Kaisaki, Pamela J.,
Megel, Natalia,
Danoy, Patrick,
Copley, Richard R.,
Broxholme, John,
Witzgall, Ralph ,
Lathrop, Mark,
Gretz, Norbert und
Gauguier, Dominique
(2005)
Missense Mutation in Sterile α Motif of Novel Protein SamCystin is Associated with Polycystic Kidney Disease in (cy/+) Rat.
Journal of the American Society of Nephrology 16 (12), S. 3517-3526.
Volltext nicht vorhanden.
2004
2002
1994
Witzgall, Ralph,
Brown, Dennis,
Schwarz, Cordula und
Bonventre, Joseph V.
(1994)
Localization of proliferating cell nuclear antigen, vimentin, c-Fos, and clusterin in the postischemic kidney. Evidence for a heterogenous genetic response among nephron segments, and a large pool of mitotically active and dedifferentiated cells.
The Journal of Clinical Investigation 93 (5), S. 2175-2188.
1993
Witzgall, Ralph,
O'Leary, Eileen,
Gessner, Reinhard,
Ouellette, Andre J. und
Bonventre, Joseph V.
(1993)
Kid-1, a putative renal transcription factor: regulation during ontogeny and in response to ischemia and toxic injury.
Molecular and Cellular Biology 13 (3), S. 1933-1942.
1992
Dummer, Reinhard,
Posseckert, Gerhard,
Nestle, Frank,
Witzgall, Ralph,
Burger, Mathias,
Becker, Jürgen C.,
Schäfer, Erwin,
Wiede, Johannes,
Sebald, Walter und
Burg, Günter
(1992)
Soluble Interleukin-2 Receptors Inhibit Interleukin 2-Dependent Proliferation and Cytotoxicity: Explanation for Diminished Natural Killer Cell Activity in Cutaneous T-Cell Lymphomas In Vivo?
Journal of Investigative Dermatology 98 (1), S. 50-54.
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