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Bactericidal/Permeability-Increasing Protein Is an Enhancer of Bacterial Lipoprotein Recognition

Bülow, Sigrid, Zeller, Lisa, Werner, Maren, Toelge, Martina, Holzinger, Jonas, Entzian, Clemens, Schubert, Thomas, Waldow, Franziska, Gisch, Nicolas, Hammerschmidt, Sven and Gessner, André (2018) Bactericidal/Permeability-Increasing Protein Is an Enhancer of Bacterial Lipoprotein Recognition. Frontiers in Immunology 9 (2768), pp. 1-16.

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Date of publication of this fulltext: 29 Jan 2019 12:23

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Other URL: http://doi.org/10.3389/fimmu.2018.02768, https://www.frontiersin.org/articles/10.3389/fimmu.2018.02768/full


Abstract

Adequate perception of immunologically important pathogen-associated molecular patterns like lipopolysaccharide and bacterial lipoproteins is essential for efficient innate and adaptive immune responses. In the context of Gram-negative infection, bactericidal/permeability-increasing protein (BPI) neutralizes endotoxic activity of lipopolysaccharides, and thus prohibits hyperactivation. So far, no ...

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Item type:Article
Date:5 December 2018
Institutions:Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.3389/fimmu.2018.02768DOI
Keywords:bactericidal/permeability-increasing protein, pro-inflammatory, bacterial lipoprotein, lipoteichoic acid, Streptococcus pneumoniae, Gram-positive, pattern recognition
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:38277
Owner only: item control page

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