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The C-terminal region of Net1 is an activator of RNA polymerase I transcription with conserved features from yeast to human

Hannig, Katharina, Babl, Virginia, Hergert, Kristin, Maier, Andreas, Pilsl, Michael, Schächner, Christopher, Stöckl, Ulrike, Milkereit, Philipp , Tschochner, Herbert , Seufert, Wolfgang and Griesenbeck, Joachim (2019) The C-terminal region of Net1 is an activator of RNA polymerase I transcription with conserved features from yeast to human. PLOS Genetics 15 (2), e1008006.

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Date of publication of this fulltext: 03 May 2019 11:23

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Other URL: http://doi.org/10.1371/journal.pgen.1008006


Abstract

RNA polymerase I (Pol I) synthesizes ribosomal RNA (rRNA) in all eukaryotes, accounting for the major part of transcriptional activity in proliferating cells. Although basal Pol I transcription factors have been characterized in diverse organisms, the molecular basis of the robust rRNA production in vivo remains largely unknown. In S. cerevisiae, the multifunctional Net1 protein was reported to ...

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Item type:Article
Date:25 February 2019
Institutions:Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie III > Prof. Dr. Herbert Tschochner
Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie III > Dr. Joachim Griesenbeck
Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie III > Dr. Philipp Milkereit
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.1371/journal.pgen.1008006DOI
Dewey Decimal Classification:500 Science > 570 Life sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:40173
Owner only: item control page

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