Hannig, Katharina, Babl, Virginia, Hergert, Kristin, Maier, Andreas, Pilsl, Michael, Schächner, Christopher, Stöckl, Ulrike, Milkereit, Philipp 
, Tschochner, Herbert , Seufert, Wolfgang and Griesenbeck, Joachim
(2019)
The C-terminal region of Net1 is an activator of RNA polymerase I transcription with conserved features from yeast to human.
PLOS Genetics 15 (2), e1008006.
| License: Creative Commons Attribution 4.0 Download (3MB) |
Other URL: http://doi.org/10.1371/journal.pgen.1008006
Abstract
RNA polymerase I (Pol I) synthesizes ribosomal RNA (rRNA) in all eukaryotes, accounting for the major part of transcriptional activity in proliferating cells. Although basal Pol I transcription factors have been characterized in diverse organisms, the molecular basis of the robust rRNA production in vivo remains largely unknown. In S. cerevisiae, the multifunctional Net1 protein was reported to ...
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| Item type: | Article | ||||
|---|---|---|---|---|---|
| Date: | 25 February 2019 | ||||
| Institutions: | Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie III > Prof. Dr. Herbert Tschochner Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie III > Dr. Joachim Griesenbeck Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie III > Dr. Philipp Milkereit | ||||
| Projects: | Open Access Publizieren (DFG) | ||||
| Identification Number: |
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| Dewey Decimal Classification: | 500 Science > 570 Life sciences | ||||
| Status: | Published | ||||
| Refereed: | Yes, this version has been refereed | ||||
| Created at the University of Regensburg: | Yes | ||||
| Item ID: | 40173 |
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