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Structure-based development of caged dopamine D2/D3 receptor antagonists

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Gienger, Marie ; Hübner, Harald ; Löber, Stefan ; König, Burkhard ; Gmeiner, Peter
License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 27 Jan 2020 14:42


Dopamine is a neurotransmitter of great physiological relevance. Disorders in dopaminergic signal transduction are associated with psychiatric and neurological pathologies such as Parkinson's disease, schizophrenia and substance abuse. Therefore, a detailed understanding of dopaminergic neurotransmission may provide access to novel therapeutic strategies for the treatment of these diseases. Caged ...


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