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Anzahl der Einträge in dieser Kategorie: 641.

Zimmer, Oliver und Goepferich, Achim (2024) On the uncertainty of the correlation between nanoparticle avidity and biodistribution. European Journal of Pharmaceutics and Biopharmaceutics 198, S. 114240.

Hosmann, Arthur, Moser, Miriam M, van Os, Wisse, Gramms, Leon, al Jalali, Valentin, Sanz Codina, Maria, Plöchl, Walter, Lier, Constantin, Kees, Frieder , Dorn, Christoph , Rössler, Karl, Reinprecht, Andrea und Zeitlinger, Markus (2024) Linezolid brain penetration in neurointensive care patients. Journal of Antimicrobial Chemotherapy, dkae025.

Beck, Sebastian (2024) Core-Shell Nanoparticles as a Platform Technology for the Treatment of Proliferative Ocular Diseases. Dissertation, Universität Regensburg.

Dejaco, Alexander , Dorn, Christoph , Paal, Michael, Gruber, Michael , Graf, Bernhard M. und Kees, Martin G. (2024) Determination of glomerular filtration rate “en passant” after high doses of iohexol for computed tomography in intensive care medicine—a proof of concept. Frontiers in Pharmacology 15.

Wulkersdorfer, Beatrix, Bergmann, Felix, Amann, Lisa, Fochtmann-Frana, Alexandra, Al Jalali, Valentin, Kurdina, Elizaveta, Lackner, Edith, Wicha, Sebastian G, Dorn, Christoph , Schäfer, Bruno, Ihra, Gerald, Rath, Thomas, Radtke, Christine und Zeitlinger, Markus (2023) Effect of albumin substitution on pharmacokinetics of piperacillin/tazobactam in patients with severe burn injury admitted to the ICU. Journal of Antimicrobial Chemotherapy.

Nagl, Martin, Moennich, Denise, Rosier, Niklas , Schihada, Hannes, Sirbu, Alexei, Konar, Nergis, Reyes-Resina, Irene, Navarro, Gemma, Franco, Rafael, Kolb, Peter, Annibale, Paolo und Pockes, Steffen (2023) Fluorescent Tools for the Imaging of Dopamine D2‐Like Receptors. ChemBioChem.

Rosier, Niklas , Moennich, Denise, Nagl, Martin, Schihada, Hannes, Sirbu, Alexei, Konar, Nergis, Reyes-Resina, Irene, Navarro, Gemma, Franco, Rafael, Kolb, Peter, Annibale, Paolo und Pockes, Steffen (2023) Shedding Light on the D1‐Like Receptors: A Fluorescence‐Based Toolbox for Visualization of the D1 and D5 Receptors. ChemBioChem.

Stahl, Monika (2023) Polymeric Nanoparticles for Antigen Delivery to Dendritic Cells. Dissertation, Universität Regensburg.

Bürkel, Peter, Rajbhandari, Meena und Jürgenliemk, Guido (2023) Bassia longifolia (= Madhuca longifolia): Isolation of flavan-3-ols and their contribution to the antibacterial and antidiabetic activity in vitro. Heliyon 9 (11), e21134.

Höring, Carina (2023) Split-Luciferase Complementation and Molecular Dynamics Studies for the Mini-G Protein-Based Functional Characterization of GPCRs. Dissertation, Universität Regensburg.

Geiben, Ann-Kathrin Christine Maria (2023) Analyse von Sedierung als unerwünschte Arzneimittelwirkung und Entwicklung eines Risikoscores für die Gerontopsychiatrie. Dissertation, Universität Regensburg.

Greppmair, Sebastian, Brinkmann, Alexander, Roehr, Anka, Frey, Otto, Hagel, Stefan, Dorn, Christoph , Marsot, Amélie, El-Haffaf, Ibrahim, Zoller, Michael, Saller, Thomas, Zander, Johannes, Schatz, Lea Marie, Scharf, Christina, Briegel, Josef, Minichmayr, Iris K., Wicha, Sebastian G. und Liebchen, Uwe (2023) Towards model-informed precision dosing of piperacillin: multicenter systematic external evaluation of pharmacokinetic models in critically ill adults with a focus on Bayesian forecasting. Intensive Care Medicine.

Ziegler, Christian (2023) Development of Injectable Anhydrous Hydrogels for the Controlled Release of Therapeutic Proteins. Dissertation, Universität Regensburg.

Bohley, Marilena , Dillinger, Andrea E., Braunger, Barbara M., Tamm, Ernst R. und Goepferich, Achim (2023) Intravenous injection of cyclosporin A loaded lipid nanocapsules fights inflammation and immune system activation in a mouse model of diabetic retinopathy. Drug Delivery and Translational Research.

Chen, Zhendong, Taubert, Max, Chen, Chunli, Dokos, Charalambos, Fuhr, Uwe, Weig, Thomas, Zoller, Michael, Heck, Suzette, Dimitriadis, Konstantinos, Terpolilli, Nicole, Kinast, Christina, Scharf, Christina, Lier, Constantin, Dorn, Christoph und Liebchen, Uwe (2023) Plasma and Cerebrospinal Fluid Population Pharmacokinetics of Vancomycin in Patients with External Ventricular Drain. Antimicrobial Agents and Chemotherapy. Volltext nicht vorhanden.

Wirth, Ulrike, Erl, Julia, Azzam, Saphia, Hoering, Carina, Skiba, Michael, Singh, Ritu, Hochmuth, Kathrin, Keller, Max , Wegener, Joachim und König, Burkhard (2023) Monitoring the Reversibility of GPCR Signaling by Combining Photochromic Ligands with Label-free Impedance Analysis. Angewandte Chemie International Edition, e202215547.

Grätz, Lukas (2023) Luminescence-based methods for the investigation of ligand binding and GRK2 recruitment to GPCRs. Dissertation, Universität Regensburg.

Hoffelner, Beate Sandra, Andreev, Stanislav , Plank, Nicole und Koch, Pierre (2023) Photocaging of Pyridinylimidazole-Based Covalent JNK3 Inhibitors Affords Spatiotemporal Control of the Binding Affinity in Live Cells. Pharmaceuticals 16 (2), S. 264.

Prüschenk, Sally (2023) Molekulare und physiologische Funktion von IRAG2 in Thrombozyten und im Pankreas. Dissertation, Universität Regensburg.

Zimmer, Oliver und Goepferich, Achim (2022) How clathrin-coated pits control nanoparticle avidity for cells. Nanoscale Horizons, (Advance Art.).

Sanz-Codina, Maria, Wicha, Sebastian G, Wulkersdorfer, Beatrix, Al Jalali, Valentin, Van Os, Wisse, Vossen, Matthias G, Bauer, Martin, Lackner, Edith, Dorn, Christoph und Zeitlinger, Markus (2022) Comparison of ultrafiltration and microdialysis for ceftriaxone protein-binding determination. Journal of Antimicrobial Chemotherapy. Volltext nicht vorhanden.

Jorda, Anselm , Wulkersdorfer, Beatrix, Schoergenhofer, Christian, Matzneller, Peter, Jalali, Valentin A. L., Bauer, Martin, Wölfl‐Duchek, Michael, Lackner, Edith, Dorn, Christoph , Jilma, Bernd und Zeitlinger, Markus (2022) Effect of the human endotoxin challenge on tedizolid tissue penetration. British Journal of Clinical Pharmacology, (accept.art.). Volltext nicht vorhanden.

Schindler, Lisa, Moosbauer, Jutta, Schmidt, Daniel , Spruss, Thilo, Grätz, Lukas, Lüdeke, Steffen, Hofheinz, Frank, Meister, Sebastian, Echtenacher, Bernd, Bernhardt, Günther, Pietzsch, Jens , Hellwig, Dirk und Keller, Max (2022) Development of a Neurotensin-Derived 68Ga-Labeled PET Ligand with High In Vivo Stability for Imaging of NTS1 Receptor-Expressing Tumors. Cancers 14 (19), S. 4922.

Forster, Lisa (2022) Development of radioligand binding and functional assays for the characterization of dopamine D2-like receptor ligands. Dissertation, Universität Regensburg.

Bohley, Marilena (2022) Targeted Lipid Nanoparticles for Retinal Drug Delivery. Dissertation, Universität Regensburg.

Bohley, Marilena, Dillinger, Andrea E., Schweda, Frank, Ohlmann, Andreas, Braunger, Barbara M., Tamm, Ernst R. und Goepferich, Achim (2022) A single intravenous injection of cyclosporin A–loaded lipid nanocapsules prevents retinopathy of prematurity. Science Advances 8 (38).

Ziegler, Christian, Graf, Moritz, Nagaoka, Makoto und Goepferich, Achim (2022) Investigation of the Impact of Hydrolytically Cleavable Groups on the Stability of Poly(ethylene glycol) Based Hydrogels Cross-Linked via the Inverse Electron Demand Diels-Alder (iEDDA) Reaction. Macromolecular Bioscience 22 (12), S. 2200226.

Heinl, Elena-Sofia, Lorenz, Sebastian, Schmidt, Barbara , Laqtom, Nouf Nasser M., Mazzulli, Joseph R., Francelle, Laetitia , Yu, Timothy W., Greenberg, Benjamin , Storch, Stephan, Tegtmeier, Ines, Othmen, Helga, Maurer, Katja, Steinfurth, Malin, Witzgall, Ralph, Milenkovic, Vladimir M., Wetzel, Christian H. und Reichold, Markus (2022) CLN7/MFSD8 may be an important factor for SARS-CoV-2 cell entry. iScience 25 (10), S. 105082.

Andreev, Stanislav , Plank, Nicole, Schollmeyer, Dieter und Koch, Pierre (2022) (S)-3-(3-((7-Ethynyl-9H-pyrimido[4,5-b]indol-4-yl)amino)piperidin-1-yl)propanenitrile. Molbank 2022 (3), M1437.

Dorn, Christoph , Petroff, David, Kratzer, Alexander, Kees, Frieder, Kloft, Charlotte, Zeitlinger, Markus , Wrigge, Hermann und Simon, Philipp (2022) Tigecycline Soft Tissue Penetration in Obese and Non-obese Surgical Patients Determined by Using In Vivo Microdialysis. European Journal of Drug Metabolism and Pharmacokinetics 47, S. 749-755.

Meurer, Florian , Dolomanov, Oleg V., Hennig, Christoph , Peyerimhoff, Norbert , Kleemiss, Florian , Puschmann, Horst und Bodensteiner, Michael (2022) Refinement of anomalous dispersion correction parameters in single-crystal structure determinations. IUCrJ / International Union of Crystallography 9 (5), S. 604-609.

Willkomm, Sarah , Jakob, Leonhard, Kramm, Kevin, Graus, Veronika, Neumeier, Julia, Meister, Gunter und Grohmann, Dina (2022) Single-molecule FRET uncovers hidden conformations and dynamics of human Argonaute 2. Nature Communications 13, art.no.3825.

Schlossmann, Jens (2022) Editorial of the Special Issue: cGMP-Signaling in Cells and Tissues: Molecular, Functional and Pharmacological Aspects. International Journal of Molecular Sciences 23 (12), S. 6482.

Forster, Lisa und Pockes, Steffen (2022) Investigating the ligand agonism and antagonism at the D2long receptor by dynamic mass redistribution. Scientific Reports 12 (1).

Braun, Daniel Simon (2022) Asymmetrisches Dimethylarginin bei psychiatrischen Erkrankungen. Dissertation, Universität Regensburg.

Bresinsky, Merlin, Strasser, Jessica M., Hubmann, Alexander, Vallaster, Bernadette, McCue, William M., Fuller, Jessica, Singh, Gurpreet, Nelson, Kathryn M., Cuellar, Matthew E., Finzel, Barry C., Ashe, Karen H., Walters, Michael A. und Pockes, Steffen (2022) Characterization of caspase‐2 inhibitors based on specific sites of caspase‐2‐mediated proteolysis. Archiv der Pharmazie 355 (9), S. 2200095.

Majer, Michael (2022) Splenomegalie assoziierte Anämie in Folge der Defizienz des PKGIβ/IRAG1-Signalweges. Dissertation, Universität Regensburg.

Endres, Katharina Walburga Maria (2022) Wirkstoffkonzentrationsbestimmungen zur Therapieleitung der medikamentösen Behandlung kardiovaskulärer Erkrankungen bei psychiatrischen Patienten. Dissertation, Universität Regensburg.

Stahl, Monika, Holzinger, Jonas M., Bülow, Sigrid und Goepferich, Achim (2022) Enzyme-triggered antigen release enhances cross presentation by dendritic cells. Nanomedicine: Nanotechnology, Biology, and Medicine 42, S. 102545. Volltext nicht vorhanden.

Jorda, Anselm , Wulkersdorfer, Beatrix, Schörgenhofer, Christian, Matzneller, Peter , Al Jalali, Valentin, Bauer, Martin , Wölf-Duchek, Michael, Lackner, Edith, Dorn, Christoph, Jilma, Bernd und Zeitlinger, Markus (2022) Influence of tedizolid on the cytokine response to the endotoxin challenge in healthy volunteers: a cross-over trial. Journal of Antimicrobial Chemotherapy. Volltext nicht vorhanden.

Konieczny, Adam (2022) Design, Synthesis and Pharmacological Characterization of Oligopeptidic and Non-Peptidic Neuropeptide Y Y4 Receptor Ligands. Dissertation, Universität Regensburg.

Ousingsawat, Jiraporn , Centeio, Raquel, Cabrita, Inês , Talbi, Khaoula, Zimmer, Oliver , Graf, Moritz, Göpferich, Achim , Schreiber, Rainer und Kunzelmann, Karl (2022) Airway Delivery of Hydrogel-Encapsulated Niclosamide for the Treatment of Inflammatory Airway Disease. International Journal of Molecular Sciences 23 (3), S. 1085.

Rösch, Gundula, Muschter, Dominique, Taheri, Shahed , El Bagdadi, Karima, Dorn, Christoph, Meurer, Andrea, Zaucke, Frank, Schilling, Arndt F., Grässel, Susanne, Straub, Rainer H. und Jenei-Lanzl, Zsuzsa (2022) β2-Adrenoceptor Deficiency Results in Increased Calcified Cartilage Thickness and Subchondral Bone Remodeling in Murine Experimental Osteoarthritis. Frontiers in Immunology 12.

Tahk, Maris-Johanna , Torp, Jane , Ali, Mohammed A. S. , Fishman, Dmytro, Parts, Leopold , Grätz, Lukas , Müller, Christoph , Keller, Max , Veiksina, Santa , Laasfeld, Tõnis und Rinken, Ago (2022) Live-cell microscopy or fluorescence anisotropy with budded baculoviruses—which way to go with measuring ligand binding to M 4 muscarinic receptors? Open Biology 12 (6). Volltext nicht vorhanden.

Barda, Christina, Anastasiou, Konstantina, Tzara, Ariadni, Grafakou, Maria-Eleni, Kalpoutzakis, Eleftherios, Heilmann, Joerg, Rallis, Michael, Kourounakis, Angeliki P. und Skaltsa, Helen (2022) A Bio-Guided Screening for Antioxidant, Anti-Inflammatory and Hypolipidemic Potential Supported by Non-Targeted Metabolomic Analysis of Crepis spp. Molecules 27 (19), S. 6173. Volltext nicht vorhanden.

Andreev, Stanislav, Pantsar, Tatu, Tesch, Roberta, Kahlke, Niclas, El-Gokha, Ahmed, Ansideri, Francesco, Grätz, Lukas, Romasco, Jenny, Sita, Giulia, Geibel, Christian , Lämmerhofer, Michael, Tarozzi, Andrea, Knapp, Stefan , Laufer, Stefan A. und Koch, Pierre (2022) Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors. Journal of Medicinal Chemistry 65 (2), S. 1283-1301. Volltext nicht vorhanden.

Mandigma, Mark John P. , Žurauskas, Jonas, MacGregor, Callum I., Edwards, Lee J. , Shahin, Ahmed , d'Heureuse, Ludwig, Yip, Philip, Birch, David J. S. , Gruber, Thomas, Heilmann, Jörg, John, Matthew P. und Barham, Joshua P. (2022) An organophotocatalytic late-stage N–CH3oxidation of trialkylamines toN-formamides with O2in continuous flow. Chemical Science 13 (7), S. 1912-1924. Volltext nicht vorhanden.

Katsouri, Ilektra Petrina, Vandervelpen, Ebert Vinciane G., Gattor, Albert Owusu, Engelbeen, Sarah, El Sayed, Abdulrahman, Seitaj, Klejdia, Becerra, Eduardo Daniel Morales und Vanderheyden, Patrick M.L. (2022) Complex FFA1 receptor (in)dependent modulation of calcium signaling by free fatty acids. Biochemical Pharmacology 202, S. 115150. Volltext nicht vorhanden.

Haen, Ekkehard (2022) Dose-Related Reference Range as a Tool in Therapeutic Drug Monitoring. Therapeutic Drug Monitoring 44 (4), S. 475-493. Volltext nicht vorhanden.

Schoretsanitis, Georgios, Haen, Ekkehard, Piacentino, Daria, Conca, Andreas, Endres, Katharina, Hiemke, Christoph, Gründer, Gerhard und Paulzen, Michael (2022) Effects of body weight, smoking status, and sex on plasma concentrations of once-monthly paliperidone palmitate. Expert Review of Clinical Pharmacology 15 (2), S. 243-249. Volltext nicht vorhanden.

Prüschenk, Sally und Schlossmann, Jens (2022) Function of IRAG2 Is Modulated by NO/cGMP in Murine Platelets. International Journal of Molecular Sciences 23 (12), S. 6695. Volltext nicht vorhanden.

Beyer, Mandy, Henninger, Sven J., Haehnel, Patricia S., Mustafa, Al-Hassan M. , Gurdal, Ece , Schubert, Bastian, Christmann, Markus, Sellmer, Andreas , Mahboobi, Siavosh, Drube, Sebastian, Sippl, Wolfgang, Kindler, Thomas und Krämer, Oliver H. (2022) Identification of a highly efficient dual type I/II FMS-like tyrosine kinase inhibitor that disrupts the growth of leukemic cells. Cell Chemical Biology 29 (3), 398-411.e4. Volltext nicht vorhanden.

Wachholz, Vanessa, Mustafa, Al-Hassan M., Zeyn, Yanira, Henninger, Sven J., Beyer, Mandy, Dzulko, Melanie, Piée-Staffa, Andrea, Brachetti, Christina, Haehnel, Patricia S., Sellmer, Andreas, Mahboobi, Siavosh, Kindler, Thomas, Brenner, Walburgis, Nikolova, Teodora und Krämer, Oliver H. (2022) Inhibitors of class I HDACs and of FLT3 combine synergistically against leukemia cells with mutant FLT3. Archives of Toxicology 96 (1), S. 177-193. Volltext nicht vorhanden.

Schihada, Hannes, Klompstra, Thomas M. , Humphrys, Laura J. , Cervenka, Igor, Dadvar, Shamim , Kolb, Peter , Ruas, Jorge L. und Schulte, Gunnar (2022) Isoforms of GPR35 have distinct extracellular N-termini that allosterically modify receptor-transducer coupling and mediate intracellular pathway bias. Journal of Biological Chemistry 298 (9), S. 102328. Volltext nicht vorhanden.

Lautenschlager, Florian , Weiss, Manfred, Feuerer, Sigrun und Wodarz, Norbert (2022) Kratom – eine kurze Übersicht für die Schmerzmedizin. Der Schmerz 36 (2), S. 128-134. Volltext nicht vorhanden.

Peterhoff, David , Thalhauser, Stefanie, Neckermann, Patrick , Barbey, Clara, Straub, Kristina, Nazet, Julian, Merkl, Rainer, Längst, Gernot, Breunig, Miriam und Wagner, Ralf (2022) Multivalent display of engineered HIV-1 envelope trimers on silica nanoparticles for targeting and in vitro activation of germline VRC01 B cells. European Journal of Pharmaceutics and Biopharmaceutics 181, S. 88-101. Volltext nicht vorhanden.

Schindler, Lisa, Wohlfahrt, Katrin, Gluhacevic von Krüchten, Lara, Prante, Olaf, Keller, Max und Maschauer, Simone (2022) Neurotensin analogs by fluoroglycosylation at Nω-carbamoylated arginines for PET imaging of NTS1-positive tumors. Scientific Reports 12 (1). Volltext nicht vorhanden.

Greinwald, Anja, Hartmann, Martin, Heilmann, Jörg, Heinrich, Michael, Luick, Rainer und Reif, Albert (2022) Soil and Vegetation Drive Sesquiterpene Lactone Content and Profile in Arnica montana L. Flower Heads From Apuseni-Mountains, Romania. Frontiers in Plant Science 13. Volltext nicht vorhanden.

Szczepańska, Katarzyna, Podlewska, Sabina, Dichiara, Maria, Gentile, Davide, Patamia, Vincenzo, Rosier, Niklas, Mönnich, Denise, Ruiz Cantero, Ma Carmen, Karcz, Tadeusz, Łażewska, Dorota, Siwek, Agata, Pockes, Steffen, Cobos, Enrique J., Marrazzo, Agostino, Stark, Holger, Rescifina, Antonio, Bojarski, Andrzej J., Amata, Emanuele und Kieć-Kononowicz, Katarzyna (2022) Structural and Molecular Insight into Piperazine and Piperidine Derivatives as Histamine H3 and Sigma-1 Receptor Antagonists with Promising Antinociceptive Properties. ACS Chemical Neuroscience 13 (1), S. 1-15. Volltext nicht vorhanden.

Müller, Christoph, Gleixner, Jakob , Tahk, Maris-Johanna , Kopanchuk, Sergei , Laasfeld, Tõnis, Weinhart, Michael, Schollmeyer, Dieter, Betschart, Martin U., Lüdeke, Steffen, Koch, Pierre, Rinken, Ago und Keller, Max (2022) Structure-Based Design of High-Affinity Fluorescent Probes for the Neuropeptide Y Y1 Receptor. Journal of Medicinal Chemistry 65 (6), S. 4832-4853. Volltext nicht vorhanden.

Rösch, G., El Bagdadi, K., Muschter, D., Taheri, S. , Dorn, C., Meurer, A., Straub, R.H., Zaucke, F. , Schilling, A.F., Grässel, S. und Jenei-Lanzl, Z. (2022) Sympathectomy aggravates subchondral bone changes during osteoarthritis progression in mice without affecting cartilage degeneration or synovial inflammation. Osteoarthritis and Cartilage 30 (3), S. 461-474. Volltext nicht vorhanden.

Mietzner, Raphael , Pawlak, Ramona , Tamm, Ernst R., Goepferich, Achim , Fuchshofer, Rudolf und Breunig, Miriam (2021) Angiopoietin-1 Mimetic Nanoparticles for Restoring the Function of Endothelial Cells as Potential Therapeutic for Glaucoma. Pharmaceuticals 15 (1), S. 18.

Harloff, Manuela (2021) Der sGC-Aktivator Cinaciguat als Therapieoption der diabetischen Nephropathie und Untersuchung von glukoseinduzierten molekularen Mechanismen in Mesangialzellen. Dissertation, Universität Regensburg.

Prüschenk, Sally, Majer, Michael , Schreiber, Rainer und Schlossmann, Jens (2021) IRAG2 Interacts with IP3-Receptor Types 1, 2, and 3 and Regulates Intracellular Ca2+ in Murine Pancreatic Acinar Cells. International Journal of Molecular Sciences 22 (24), S. 13409.

Busse, David, Simon, Philipp, Schmitt, Lisa, Petroff, David, Dorn, Christoph , Dietrich, Arne, Zeitlinger, Markus, Huisinga, Wilhelm, Michelet, Robin, Wrigge, Hermann und Kloft, Charlotte (2021) Comparative Plasma and Interstitial Tissue Fluid Pharmacokinetics of Meropenem Demonstrate the Need for Increasing Dose and Infusion Duration in Obese and Non-obese Patients. Clinical Pharmacokinetics.

Dorn, Christoph (2021) 3.3. Informationen über Arzneimittel. In: Sax, Michael, (ed.) Pharmazie für die Praxis : Lehrbuch für Pharmazeuten im Praktikum : Handbuch für die Apotheke. Deutscher Apotheker Verlag, Stuttgart, S. 152-173. ISBN 978-3-7692-7010-5. Volltext nicht vorhanden.

Rösch, Gundula, El Bagdadi, Karima, Muschter, Dominique , Taheri, Shahed, Dorn, Christoph , Meurer, Andrea, Straub, Rainer H. , Zaucke, Frank , Schilling, Arndt F., Grässel, Susanne und Jenei-Lanzl, Zsuzsa (2021) Sympathectomy aggravates subchondral bone changes during osteoarthritis progression in mice without affecting cartilage degeneration or synovial inflammation. Osteoarthritis and Cartilage 30 (3), S. 461-474. Volltext nicht vorhanden.

Lawrowska, Alexandra (2021) Nanoparticles for drug delivery to ocular neovascularizations. Dissertation, Universität Regensburg.

Kuck, Katrin (2021) Isolierung von terpenoiden Sekundärstoffen aus C. myrrha und pharmakologische Testung in einem ICAM-1 in vitro Modell. Dissertation, Universität Regensburg.

Tremmel, Martina, Paetzel, Christian und Heilmann, Jörg (2021) In Vitro Liver Metabolism of Six Flavonoid C-Glycosides. Molecules 26 (21), S. 1-14.

Bartole, Edith (2021) Design, Synthesis and Characterization of Molecular Tools for the Histamine H3 and H4 Receptors – In Particular Radio- and Fluorescent Ligands. Dissertation, Universität Regensburg.

Busse, David, Borghardt, Jens Markus, Petroff, David, Pevzner, Alice, Dorn, Christoph , El‐Najjar, Nahed, Huisinga, Wilhelm, Wrigge, Hermann, Simon, Philipp und Kloft, Charlotte (2021) EVALUATING PREDICTION METHODS FOR GLOMERULAR FILTRATION TO OPTIMISE DRUG DOSES IN OBESE AND NON‐OBESE PATIENTS. British Journal of Clinical Pharmacology. Volltext nicht vorhanden.

Höring, Carina , Conrad, Marcus, Söldner, Christian A. , Wang, Jinan , Sticht, Heinrich , Strasser, Andrea und Miao, Yinglong (2021) Specific Engineered G Protein Coupling to Histamine Receptors Revealed from Cellular Assay Experiments and Accelerated Molecular Dynamics Simulations. International Journal of Molecular Sciences 22 (18), S. 1-21.

Seibel-Ehlert, Ulla , Plank, Nicole, Inoue, Asuka, Bernhardt, Guenther und Strasser, Andrea (2021) Label-Free Investigations on the G Protein Dependent Signaling Pathways of Histamine Receptors. International Journal of Molecular Sciences 22 (18), S. 1-33.

Busse, David , Simon, Philipp , Petroff, David, Dorn, Christoph, Schmitt, Lisa, Bindellini, Davide, Kratzer, Alexander, Dietrich, Arne, Zeitlinger, Markus, Huisinga, Wilhelm , Michelet, Robin , Wrigge, Hermann und Kloft, Charlotte (2021) Similar Piperacillin/Tazobactam Target Attainment in Obese versus Nonobese Patients despite Differences in Interstitial Tissue Fluid Pharmacokinetics. Pharmaceutics 13 (9), S. 1380.

Heilmann, Jörg, Tremmel, Martina und Kiermaier, Josef (2021) In Vitro Metabolism of Six C-Glycosidic Flavonoids from Passiflora incarnata L. International Journal of Molecular Sciences 2021 (22), S. 6566. (Eingereicht)

Breunig, Miriam, Sonntag, Tobias, Froemel, Franziska, Stamer, W. Daniel, Ohlmann, Andreas und Fuchshofer, Rudolf (2021) Distribution of Gold Nanoparticles in the Anterior Chamber of the Eye after Intracameral Injection for Glaucoma Therapy. Pharmaceutics 2021 (13), S. 901. (Eingereicht)

Buschmann, Jonas (2021) Synthesis and pharmacological characterization of argininamide-type neuropeptide Y (NPY) Y1 and Y2 receptor antagonists and synthesis of non-peptide potential NPY Y4 receptor ligands. Dissertation, Universität Regensburg.

Peterhoff, David , Thalhauser, Stefanie, Sobczak, Jan M., Mohsen, Mona O., Voigt, Christoph, Seifert, Nicole , Neckermann, Patrick, Hauser, Alexandra , Ding, Song, Sattentau, Quentin, Bachmann, Martin F. , Breunig, Miriam und Wagner, Ralf (2021) Augmenting the Immune Response against a Stabilized HIV-1 Clade C Envelope Trimer by Silica Nanoparticle Delivery. Vaccines 9 (642), S. 1-24.

Maslanka Figueroa, Sara (2021) Heteromultivalent Virus-mimetic Nanoparticles for Specific Mesangial Cell Targeting. Dissertation, Universität Regensburg.

Schlossmann, Jens, Majer, Michael und Prueschenk, Sally (2021) Loss of PKGIβ/IRAG1 Signaling Causes Anemia-Associated Splenomegaly. International Journal of Molecular Sciences 22 (5458), S. 1-20.

Pockes, Steffen und Tropmann, Katharina (2021) Histamine H2 receptor radioligands: triumphs and challenges. Future Medicinal Chemistry 13 (12), S. 1073-1081.

Göpferich, Achim , Fleischmann, Daniel, Harloff, Manuela, Figueroa, Sara Maslanka und Schlossmann, Jens (2021) Targeted Delivery of Soluble Guanylate Cyclase (sGC) Activator Cinaciguat to Renal Mesangial Cells via Virus-Mimetic Nanoparticles Potentiates Anti-Fibrotic Effects by cGMP-Mediated Suppression of the TGF-β Pathway. International Journal of Molecular Sciences 22 (2557), S. 1-18. (Eingereicht)

Weinhart, Corinna G. (2021) Synthesis and pharmacological characterization of
dibenzodiazepinone-type muscarinic M2-receptor
antagonists conjugated to fluorescent dyes or
small peptides.
Dissertation, Universität Regensburg.

Maslanka-Figueroa, Sara , Fleischmann, Daniel und Göpferich, Achim (2021) Biomedical nanoparticle design: What we can learn from viruses. Journal of Controlled Release 329, S. 552-569. Volltext nicht vorhanden.

Hoffmeister, Helen, Fuchs, Andreas , Komives, Elizabeth, Groebner‐Ferreira, Regina, Strobl, Laura, Nazet, Julian, Heizinger, Leonhard, Merkl, Rainer, Dove, Stefan und Längst, Gernot (2021) Sequence and functional differences in the ATPase domains of CHD3 and SNF2H promise potential for selective regulability and drugability. The FEBS Journal 288, S. 4000-4023.

Rosier, Niklas, Grätz, Lukas, Schihada, Hannes , Möller, Jan, Işbilir, Ali , Humphrys, Laura J. , Nagl, Martin, Seibel, Ulla, Lohse, Martin J. und Pockes, Steffen (2021) A Versatile Sub-Nanomolar Fluorescent Ligand Enables NanoBRET Binding Studies and Single-Molecule Microscopy at the Histamine H3 Receptor. Journal of Medicinal Chemistry 64 (15), S. 11695-11708. Volltext nicht vorhanden.

Ziegler, Christian, Graf, Moritz, Beck, Sebastian und Göpferich, Achim (2021) A novel anhydrous preparation of PEG hydrogels enables high drug loading with biologics for controlled release applications. European Polymer Journal (147), S. 110286. Volltext nicht vorhanden.

Tropmann, Katharina, Bresinsky, Merlin, Forster, Lisa, Mönnich, Denise, Buschauer, Armin , Wittmann, Hans-Joachim, Hübner, Harald, Gmeiner, Peter, Pockes, Steffen und Strasser, Andrea (2021) Abolishing Dopamine D2long/D3 Receptor Affinity of Subtype-Selective Carbamoylguanidine-Type Histamine H2 Receptor Agonists. Journal of Medicinal Chemistry 64 (12), S. 8684-8709. Volltext nicht vorhanden.

Endres, Katharina, Schiller, Ernst und Haen, Ekkehard (2021) Antihypertensiva in der Psychiatrie. Der Nervenarzt 92, S. 487-792.

Groner, Jonas, Göpferich, Achim und Breunig, Miriam (2021) Atherosclerosis: Conventional intake of cardiovascular drugs versus delivery using nanotechnology - A new chance for causative therapy? Journal of Controlled Release 333, S. 539-559. Volltext nicht vorhanden.

Grätz, Lukas, Laasfeld, Tõnis, Allikalt, Anni , Gruber, Corinna G., Pegoli, Andrea, Tahk, Maris-Johanna, Tsernant, Mari-Liis, Keller, Max und Rinken, Ago (2021) BRET- and fluorescence anisotropy-based assays for real-time monitoring of ligand binding to M2 muscarinic acetylcholine receptors. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1868 (3), S. 118930. Volltext nicht vorhanden.

Kuzin, Maxim , Haen, Ekkehard, Hiemke, Christoph , Bochon, Benjamin, Bochon, Karolina, Gründer, Gerhard, Paulzen, Michael und Schoretsanitis, Georgios (2021) Body mass index as a determinant of clozapine plasma concentrations: A pharmacokinetic-based hypothesis. Journal of Psychopharmacology 35 (3), S. 273-278. Volltext nicht vorhanden.

Grafakou, Maria-Eleni, Barda, Christina, Karikas, George A., Heilmann, Joerg und Skaltsa, Helen (2021) Cajamolides A-N: Cytotoxic and anti-inflammatory sesquiterpene lactones from Calea jamaicensis. Bioorganic Chemistry 116, S. 105351. Volltext nicht vorhanden.

Gergs, Ulrich, Büxel, Maren L., Bresinsky, Merlin, Kirchhefer, Uwe, Fehse, Charlotte, Höring, Carina, Hofmann, Britt, Marušáková, Margaréta, Čináková, Aneta, Schwarz, Rebecca, Pockes, Steffen und Neumann, Joachim (2021) Cardiac Effects of Novel Histamine H2 Receptor Agonists. Journal of Pharmacology and Experimental Therapeutics 379 (3), S. 223-234. Volltext nicht vorhanden.

Stoelzle-Feix, Sonja, Juhasz, Krisztina, Skiba, Michael, Wegener, Joachim, Knox, Ronald, Lemme, Marta, Thomas, Ulrich, Engelstaedter, Max, Dragicevic, Elena, George, Michael und Fertig, Niels (2021) Cell monitoring using multi-frequency impedance recordings for label-free and time-resolved cell response analysis. Journal of Pharmacological and Toxicological Methods 111, S. 106969. Volltext nicht vorhanden.

Barda, C., Grafakou, M.-E. , Kalpoutzakis, E., Heilmann, J. und Skaltsa, H. (2021) Chemical composition of Crepis foetida L. and C. rubra L. volatile constituents and evaluation of the in vitro anti-inflammatory activity of salicylaldehyde rich volatile fraction. Biochemical Systematics and Ecology 96, S. 104256. Volltext nicht vorhanden.

Schoretsanitis, Georgios, Haen, Ekkehard, Piacentino, Daria, Conca, Andreas, Endres, Katharina, Hiemke, Christoph, Gründer, Gerhard und Paulzen, Michael (2021) Clinical response in patients treated with once-monthly paliperidone palmitate: analysis of a therapeutic drug monitoring (TDM) database. European Archives of Psychiatry and Clinical Neuroscience 271 (8), S. 1437-1443. Volltext nicht vorhanden.

Reynders, Martin, Chaikuad, Apirat, Berger, Benedict‐Tilman, Bauer, Katharina, Koch, Pierre , Laufer, Stefan, Knapp, Stefan und Trauner, Dirk (2021) Controlling the Covalent Reactivity of a Kinase Inhibitor with Light. Angewandte Chemie International Edition 60 (37), S. 20178-20183. Volltext nicht vorhanden.

Wörle, Elisabeth, Jakob, Leonhard, Schmidbauer, Andreas, Zinner, Gabriel und Grohmann, Dina (2021) Decoupling the bridge helix of Cas12a results in a reduced trimming activity, increased mismatch sensitivity and impaired conformational transitions. Nucleic Acids Research 49 (9), S. 5278-5293. Volltext nicht vorhanden.

Antoni, Frauke und Bernhardt, Günther (2021) Derivatives of nitrogen mustard anticancer agents with improved cytotoxicity. Archiv der Pharmazie 354, e2000366.

Weinhart, Corinna. G., Wifling, David, Schmidt, Maximilian. F., Neu, Eduard, Höring, Carina, Clark, Timothy, Gmeiner, Peter und Keller, Max (2021) Dibenzodiazepinone-type muscarinic receptor antagonists conjugated to basic peptides: Impact of the linker moiety and unnatural amino acids on M2R selectivity. European Journal of Medicinal Chemistry 213, S. 113159. Volltext nicht vorhanden.

Fleischmann, Daniel und Goepferich, Achim (2021) General sites of nanoparticle biodistribution as a novel opportunity for nanomedicine. European Journal of Pharmaceutics and Biopharmaceutics 166, S. 44-60. Volltext nicht vorhanden.

Max, Julianna und Heilmann, Jörg (2021) Homoadamantane and Adamantane Acylphloroglucinols from Hypericum hirsutum. Planta Medica 87 (14), S. 1167-1183. Volltext nicht vorhanden.

Ziegler, Christian E., Graf, Moritz, Nagaoka, Makoto, Lehr, Heike und Goepferich, Achim M. (2021) In Situ Forming iEDDA Hydrogels with Tunable Gelation Time Release High-Molecular Weight Proteins in a Controlled Manner over an Extended Time. Biomacromolecules 22 (8), S. 3223-3236. Volltext nicht vorhanden.

Grafakou, Maria-Eleni, Barda, Christina, Heilmann, Joerg und Skaltsa, Helen (2021) Macrocyclic Diterpenoid Constituents of Euphorbia deflexa, an Endemic Spurge from Greece. Journal of Natural Products 84 (11), S. 2893-2903. Volltext nicht vorhanden.

Gaebler, Arnim Johannes , Schoretsanitis, Georgios, Ben Omar, Nagia, Haen, Ekkehard, Endres, Katharina, Hiemke, Christoph und Paulzen, Michael (2021) Metamizole but not ibuprofen reduces the plasma concentration of sertraline: Implications for the concurrent treatment of pain and depression/anxiety disorders. British Journal of Clinical Pharmacology 87 (3), S. 1111-1119.

Konieczny, Adam, Conrad, Marcus, Ertl, Fabian J., Gleixner, Jakob, Gattor, Albert O., Grätz, Lukas, Schmidt, Maximilian F., Neu, Eduard, Horn, Anselm H. C., Wifling, David, Gmeiner, Peter, Clark, Timothy, Sticht, Heinrich und Keller, Max (2021) N-Terminus to Arginine Side-Chain Cyclization of Linear Peptidic Neuropeptide Y Y4 Receptor Ligands Results in Picomolar Binding Constants. Journal of Medicinal Chemistry 64 (22), S. 16746-16769. Volltext nicht vorhanden.

Dorn, Christoph , Petroff, David, Stoelzel, Melanie, Kees, Martin G. , Kratzer, Alexander, Dietrich, Arne, Kloft, Charlotte, Zeitlinger, Markus, Kees, Frieder , Wrigge, Hermann und Simon, Philipp (2021) Perioperative administration of cefazolin and metronidazole in obese and non-obese patients: a pharmacokinetic study in plasma and interstitial fluid. Journal of Antimicrobial Chemotherapy. Volltext nicht vorhanden.

Schoretsanitis, Georgios, Haen, Ekkehard, Piacentino, Daria, Conca, Andreas, Endres, Katharina, Carpi, Fabio, Hiemke, Christoph, Gründer, Gerhard und Paulzen, Michael (2021) Pharmacokinetic Correlates of Once-Monthly Paliperidone Palmitate-Related Adverse Drug Reactions. Clinical Pharmacokinetics 60 (12), S. 1583-1589. Volltext nicht vorhanden.

Biselli, Sabrina, Bresinsky, Merlin, Tropmann, Katharina, Forster, Lisa , Honisch, Claudia , Buschauer, Armin, Bernhardt, Günther und Pockes, Steffen (2021) Pharmacological characterization of a new series of carbamoylguanidines reveals potent agonism at the H2R and D3R. European Journal of Medicinal Chemistry 214, S. 113190. Volltext nicht vorhanden.

Al Jalali, V. , Wölfl-Duchek, M., Taubert, M. , Matzneller, P. , Lackner, E., Dorn, Christoph , Kratzer, A., Wulkersdorfer, B., Österreicher, Z und Zeitlinger, Markus (2021) Plasma and soft tissue pharmacokinetics of ceftolozane/tazobactam in healthy volunteers after single and multiple intravenous infusion: a microdialysis study. Journal of Antimicrobial Chemotherapy. Volltext nicht vorhanden.

Grafakou, Maria-Eleni, Barda, Christina, Pintać, Diandra, Lesjak, Marija, Heilmann, Jörg und Skaltsa, Helen (2021) Prenylated Acylphloroglucinols from Hypericum jovis with Anti-inflammatory Potential. Planta Medica 87 (14), S. 1184-1191. Volltext nicht vorhanden.

Ibrahim, Ahmed B. M., Mahmoud, Ghada Abd‐Elmonsef , Meurer, Florian und Bodensteiner, Michael (2021) Preparation and crystallographic studies of a new mercuric salicylaldimine complex for fabrication of microscaled and nanoscaled mercuric sulfide as antimicrobial agents against human pathogenic yeasts and filamentous fungi. Applied Organometallic Chemistry 35 (3). Volltext nicht vorhanden.

Aldag, Pierre, Welzel, Fabian, Jakob, Leonhard, Schmidbauer, Andreas, Rutkauskas, Marius, Fettes, Fergus, Grohmann, Dina und Seidel, Ralf (2021) Probing the stability of the SpCas9–DNA complex after cleavage. Nucleic Acids Research 49 (21), S. 12411-12421. Volltext nicht vorhanden.

Wulkersdorfer, Beatrix, Wicha, Sebastian G., Kurdina, Elizaveta, Carrion Carrera, Stephan F., Matzneller, Peter, Al Jalali, Valentin, Vossen, Matthias G., Riesenhuber, Sonja, Lackner, Edith, Dorn, Christoph und Zeitlinger, Markus (2021) Protein binding of clindamycin in vivo by means of intravascular microdialysis in healthy volunteers. Journal of Antimicrobial Chemotherapy. Volltext nicht vorhanden.

Daskalaki, Artemis, Grafakou, Maria-Eleni , Barda, Christina, Kypriotakis, Zacharias, Heilmann, Jörg und Skaltsa, Helen (2021) Secondary metabolites from Hypericum trichocaulon Boiss. & Heldr., growing wild in the island of crete. Biochemical Systematics and Ecology 97, S. 104294. Volltext nicht vorhanden.

Eitel, Michael , Zinad, Dhafer S. , Schollmeyer, Dieter, Gross, Harald und Koch, Pierre (2021) Selective mono-de-O-acetylation of the per-O-acetylated brasilicardin carbohydrate side chain. Carbohydrate Research 504, S. 108312. Volltext nicht vorhanden.

Tropmann, Katharina, Seibel-Ehlert, Ulla, Littmann, Timo und Strasser, Andrea (2021) Shining light on the histamine H2 receptor: Synthesis of carbamoylguanidine-type agonists as a pharmacological tool to study internalization. Bioorganic & Medicinal Chemistry Letters 52, S. 128388. Volltext nicht vorhanden.

Szczepańska, Katarzyna , Pockes, Steffen , Podlewska, Sabina, Höring, Carina, Mika, Kamil, Latacz, Gniewomir, Bednarski, Marek, Siwek, Agata , Karcz, Tadeusz, Nagl, Martin, Bresinsky, Merlin, Mönnich, Denise, Seibel, Ulla, Kuder, Kamil J. , Kotańska, Magdalena, Stark, Holger, Elz, Sigurd und Kieć-Kononowicz, Katarzyna (2021) Structural modifications in the distal, regulatory region of histamine H3 receptor antagonists leading to the identification of a potent anti-obesity agent. European Journal of Medicinal Chemistry 213, S. 113041. Volltext nicht vorhanden.

Eap, C. B. , Gründer, G. , Baumann, P. , Ansermot, N., Conca, A., Corruble, E., Crettol, S., Dahl, M. L., de Leon, J. , Greiner, C., Howes, O., Kim, E., Lanzenberger, R., Meyer, J. H., Moessner, R., Mulder, H., Müller, D. J., Reis, M., Riederer, P., Ruhe, H. G., Spigset, O., Spina, E., Stegman, B., Steimer, W., Stingl, J. , Suzen, S., Uchida, H., Unterecker, S., Vandenberghe, F. und Hiemke, C. (2021) Tools for optimising pharmacotherapy in psychiatry (therapeutic drug monitoring, molecular brain imaging and pharmacogenetic tests): focus on antidepressants. The World Journal of Biological Psychiatry 22 (8), S. 561-628. Volltext nicht vorhanden.

Kuck, Katrin, Jürgenliemk, Guido, Lipowicz, Bartosz und Heilmann, Jörg (2020) Sesquiterpenes from Myrrh and Their ICAM-1 Inhibitory Activity In Vitro. Molecules 26 (1), S. 42.

Höring, Carina , Seibel, Ulla , Tropmann, Katharina, Grätz, Lukas , Mönnich, Denise , Pitzl, Sebastian, Bernhardt, Günther , Pockes, Steffen und Strasser, Andrea (2020) A Dynamic, Split-Luciferase-Based Mini-G Protein Sensor to Functionally Characterize Ligands at All Four Histamine Receptor Subtypes. International Journal of Molecular Sciences 21 (22), S. 8440.

Antoni, Frauke , Wifling, David und Bernhardt, Günther (2020) Water-soluble inhibitors of ABCG2 (BCRP) – A fragment-based and computational approach. European Journal of Medicinal Chemistry, S. 112958. Volltext nicht vorhanden.

Simeth, Nadja Anita , Kinateder, Thomas, Rajendran, Chitra, Nazet, Julian, Merkl, Rainer , Sterner, Reinhard , König, Burkhard und Kneuttinger, Andrea C. (2020) Towards Photochromic Azobenzene‐Based Inhibitors for Tryptophan Synthase. Chemistry—A European Journal 27, S. 2439-2451.

Bahr, Lisa-Marie (2020) Investigating the role of the central and the peripheral
benzodiazepine receptor on stress and anxiety related
parameters.
Dissertation, Universität Regensburg.

Naporra, Franziska Gertraud (2020) Synthese und pharmakologische Charakterisierung neuer trizyklischer Liganden am Histamin-H1/H4-Rezeptor. Dissertation, Universität Regensburg.

Grätz, Lukas, Tropmann, Katharina, Bresinsky, Merlin, Müller, Christoph, Bernhardt, Günther und Pockes, Steffen (2020) NanoBRET binding assay for histamine H2 receptor ligands using live recombinant HEK293T cells. Scientific Reports 10, S. 13288.

Schwarz, Mirjam (2020) Erstellung eines Hypotonie-Risikoscores und Validierung anhand einer retrospektiven Anwendungsbeobachtung an geriatrischen Patienten. Dissertation, Universität Regensburg.

Mietzner, Raphael , Kade, Christian, Froemel, Franziska, Pauly, Diana, Stamer, W. Daniel, Ohlmann, Andreas, Wegener, Joachim, Fuchshofer, Rudolf und Breunig, Miriam (2020) Fasudil Loaded PLGA Microspheres as Potential Intravitreal Depot Formulation for Glaucoma Therapy. Pharmaceutics 12 (8), S. 706.

Habs, Michael und Koller, Michael (2020) Material Risks of Homeopathic Medicinal Products: Regulatory Frameworks, Results of Preclinical Toxicology, and Clinical Meta-Analyses and Their Implications. Complementary Medicine Research 21 (1), S. 64-84.

Littmann, Timo (2020) Towards a method for the simultaneous quantification of Gαq activation β-arrestin2 recruitment. Dissertation, Universität Regensburg.

Bartole, Edith, Grätz, Lukas, Littmann, Timo, Wifling, David , Seibel, Ulla, Buschauer, Armin und Bernhardt, Günther (2020) UR-DEBa242: A Py-5-Labeled Fluorescent Multipurpose Probe for Investigations on the Histamine H3 and H4 Receptors. Journal of Medicinal Chemistry 63 (10), S. 5297-5311. Volltext nicht vorhanden.

Maslanka Figueroa, Sara , Fleischmann, Daniel, Beck, Sebastian, Tauber, Philipp, Witzgall, Ralph, Schweda, Frank und Goepferich, Achim (2020) Nanoparticles Mimicking Viral Cell Recognition Strategies Are Superior Transporters into Mesangial Cells. Advanced Science 7 (11), S. 1903204.

Guter, Michaela (2020) Layer-by-layer nanoparticles for glaucoma therapy. Dissertation, Universität Regensburg.

Dorn, Christoph , Schießer, Selina, Wulkersdorfer, Beatrix, Hitzenbichler, Florian, Kees, Martin G. und Zeitlinger, Markus (2020) Determination of free clindamycin, flucloxacillin or tedizolid in plasma: Keep attention to physiological conditions when using ultrafiltration. Biomedical Chromatography 34, e4820.

Goepferich, Achim , Maslanka-Figueroa, Sara, Fleischmann, Daniel und Beck, Sebastian (2020) Thermodynamic, Spatial and Methodological Considerations for the Manufacturing of Therapeutic Polymer Nanoparticles. Pharmaceutical Research 37 (59).

Veser, Anika (2020) Multivalently binding antagonists for the neurokinin-1 receptor. Dissertation, Universität Regensburg.

Abstiens, Kathrin (2020) Heteromultivalent Nanoparticles for Selective Targeting of Renal Cells. Dissertation, Universität Regensburg.

Koehler, Katrin, Hmida, Dorra, Schlossmann, Jens, Landgraf, Dana, Reisch, Nicole, Schuelke, Markus und Huebner, Angela (2020) Homozygous mutation in murine retrovirus integration site 1 gene associated with a non‐syndromic form of isolated familial achalasia. Neurogastroenterology & Motility 32 (12). Volltext nicht vorhanden.

Sellmer, Andreas, Pilsl, Bernadette, Beyer, Mandy, Pongratz, Herwig, Wirth, Lukas, Elz, Sigurd, Dove, Stefan, Henninger, Sven Julian, Spiekermann, Karsten, Polzer, Harald, Klaeger, Susan, Kuster, Bernhard, Böhmer, Frank D., Fiebig, Heinz-Herbert, Krämer, Oliver H. und Mahboobi, Siavosh (2020) A series of novel aryl-methanone derivatives as inhibitors of FMS-like tyrosine kinase 3 (FLT3) in FLT3-ITD-positive acute myeloid leukemia. European Journal of Medicinal Chemistry 193, S. 112232. Volltext nicht vorhanden.

Fleischmann, Daniel, Maslanka-Figueroa, Sara, Beck, Sebastian, Abstiens, Kathrin, Witzgall, Ralph, Schweda, Frank, Tauber, Philipp und Goepferich, Achim (2020) Adenovirus-Mimetic Nanoparticles: Sequential Ligand-Receptor Interplay as a Universal Tool for Enhanced In Vitro/In Vivo Cell Identification. ACS Applied Materials & Interfaces 12 (31), S. 34689-34702. Volltext nicht vorhanden.

Spinnler, Katrin, von Krüchten, Lara, Konieczny, Adam, Schindler, Lisa, Bernhardt, Günther und Keller, Max (2020) An Alkyne-functionalized Arginine for Solid-Phase Synthesis Enabling “Bioorthogonal” Peptide Conjugation. ACS Medicinal Chemistry Letters 11 (3), S. 334-339. Volltext nicht vorhanden.

Braun, Daniel , Schlossmann, Jens und Haen, Ekkehard (2020) An innovative, time- and cost-saving method for the quantification of asymmetric dimethylarginine in serum by HPLC without evaporation. Separation Science Plus 3, S. 571-577.

Braun, Daniel, Schlossmann, Jens und Haen, Ekkehard (2020) An innovative, time‐ and cost‐saving method for the quantification of asymmetric dimethylarginine in serum by high‐performance liquid chromatography without evaporation. Separation Science Plus 3 (11-12), S. 571-577.

Weber, Laura, Kuck, Katrin, Jürgenliemk, Guido, Heilmann, Jörg, Lipowicz, Bartosz und Vissiennon, Cica (2020) Anti-Inflammatory and Barrier-Stabilising Effects of Myrrh, Coffee Charcoal and Chamomile Flower Extract in a Co-Culture Cell Model of the Intestinal Mucosa. Biomolecules 10 (7), S. 1033. Volltext nicht vorhanden.

Buschmann, Jonas, Seiler, Theresa, Bernhardt, Günther, Keller, Max und Wifling, David (2020) Argininamide-type neuropeptide Y Y1 receptor antagonists: the nature of Nω-carbamoyl substituents determines Y1R binding mode and affinity. RSC Medicinal Chemistry 11 (2), S. 274-282. Volltext nicht vorhanden.

Ullah, Sami, Beer, Ronny, Fuhr, Uwe, Taubert, Max , Zeitlinger, Markus, Kratzer, Alexander, Dorn, Christoph, Arshad, Usman, Kofler, Mario und Helbok, Raimund (2020) Brain Exposure to Piperacillin in Acute Hemorrhagic Stroke Patients Assessed by Cerebral Microdialysis and Population Pharmacokinetics. Neurocritical Care.

Liebchen, Uwe, Dorn, Christoph , Kees, Martin, Schiesser, Selina, Hitzenbichler, Florian, Kees, Frieder und Paal, Michael (2020) Comment on “Meropenem, Cefepime, and Piperacillin Protein Binding in Patient Samples”. Therapeutic Drug Monitoring 42 (6), S. 909-910. Volltext nicht vorhanden.

Thalhauser, Stefanie, Peterhoff, David, Wagner, Ralf und Breunig, Miriam (2020) Critical design criteria for engineering a nanoparticulate HIV-1 vaccine. Journal of Controlled Release 317, S. 322-335. Volltext nicht vorhanden.

Bohley, Marilena S., Birch, Emily, Baumann, Felix J., Dillinger, Andrea E., Tamm, Ernst R. und Goepferich, Achim M. (2020) Design of dye and superparamagnetic iron oxide nanoparticle loaded lipid nanocapsules with dual detectability in vitro and in vivo. International Journal of Pharmaceutics 585, S. 119433. Volltext nicht vorhanden.

Schihada, Hannes , Ma, Xiaoyuan, Zabel, Ulrike, Vischer, Henry F., Schulte, Gunnar , Leurs, Rob, Pockes, Steffen und Lohse, Martin J. (2020) Development of a Conformational Histamine H3 Receptor Biosensor for the Synchronous Screening of Agonists and Inverse Agonists. ACS Sensors 5 (6), S. 1734-1742. Volltext nicht vorhanden.

Gruber, Corinna G., Pegoli, Andrea, Müller, Christoph, Grätz, Lukas, She, Xueke und Keller, Max (2020) Differently fluorescence-labelled dibenzodiazepinone-type muscarinic acetylcholine receptor ligands with high M2R affinity. RSC Medicinal Chemistry 11 (7), S. 823-832. Volltext nicht vorhanden.

Andreev, Stanislav, Pantsar, Tatu , El-Gokha, Ahmed, Ansideri, Francesco, Kudolo, Mark, Anton, Débora Bublitz, Sita, Giulia , Romasco, Jenny, Geibel, Christian, Lämmerhofer, Michael , Goettert, Márcia Ines, Tarozzi, Andrea, Laufer, Stefan A. und Koch, Pierre (2020) Discovery and Evaluation of Enantiopure 9H-pyrimido[4,5-b]indoles as Nanomolar GSK-3β Inhibitors with Improved Metabolic Stability. International Journal of Molecular Sciences 21 (21), S. 7823. Volltext nicht vorhanden.

Tropmann, Katharina, Höring, Carina , Plank, Nicole und Pockes, Steffen (2020) Discovery of a G Protein-Biased Radioligand for the Histamine H2 Receptor with Reversible Binding Properties. Journal of Medicinal Chemistry 63 (21), S. 13090-13102. Volltext nicht vorhanden.

Keller, Max, Mahuroof, Shahani A., Hong Yee, Vivyanne, Carpenter, Jessica, Schindler, Lisa, Littmann, Timo, Pegoli, Andrea, Hübner, Harald, Bernhardt, Günther, Gmeiner, Peter und Holliday, Nicholas D. (2020) Fluorescence Labeling of Neurotensin(8–13) via Arginine Residues Gives Molecular Tools with High Receptor Affinity. ACS Medicinal Chemistry Letters 11 (1), S. 16-22. Volltext nicht vorhanden.

Biselli, Sabrina, Alencastre, Inês, Tropmann, Katharina, Erdmann, Daniela, Chen, Mengya, Littmann, Timo, Maia, André F. , Gomez-Lazaro, Maria, Tanaka, Miho, Ozawa, Takeaki, Keller, Max, Lamghari, Meriem, Buschauer, Armin und Bernhardt, Günther (2020) Fluorescent H2 Receptor Squaramide-Type Antagonists: Synthesis, Characterization, and Applications. ACS Medicinal Chemistry Letters 11 (8), S. 1521-1528. Volltext nicht vorhanden.

Abdellatif, Ahmed , Hennig, Robert, Pollinger, Klaus, Tawfeek, Hesham, Goepferich, Achim und make_name_string expected hash reference (2020) Fluorescent Nanoparticles Coated with a Somatostatin Analogue Target Blood Monocyte for Efficient Leukaemia Treatment. Pharmaceutical Research 37 (11), S. 2017.

Sommer, Judith, Dorn, Christoph , Gäbele, Erwin, Bataille, Frauke, Freese, Kim, Seitz, Tatjana, Thasler, Wolfgang E., Büttner, Reinhard, Weiskirchen, Ralf , Bosserhoff, Anja und Hellerbrand, Claus (2020) Four-And-A-Half LIM-Domain Protein 2 (FHL2) Deficiency Aggravates Cholestatic Liver Injury. Cells 9 (1), S. 248.

Apaolaza, P.S. , Busch, M., Asin-Prieto, E. , Peynshaert, K. , Rathod, R., Remaut, K., Dünker, N. und Göpferich, A. (2020) Hyaluronic acid coating of gold nanoparticles for intraocular drug delivery: Evaluation of the surface properties and effect on their distribution. Experimental Eye Research 198, S. 108151. Volltext nicht vorhanden.

Biswas, Siladitta, Kojonazarov, Baktybek, Hadzic, Stefan, Majer, Michael, Bajraktari, Ganimete, Novoyatleva, Tatyana, Ghofrani, Hossein Ardeschir, Grimminger, Friedrich, Seeger, Werner, Weissmann, Norbert, Schlossmann, Jens und Schermuly, Ralph Theo (2020) IRAG1 Deficient Mice Develop PKG1β Dependent Pulmonary Hypertension. Cells 9 (10), S. 2280. Volltext nicht vorhanden.

Yagati, Ajay Kumar , Behrent, Arne, Beck, Sebastian, Rink, Simone, Goepferich, Achim M., Min, Junhong , Lee, Min-Ho und Baeumner, Antje J. (2020) Laser-induced graphene interdigitated electrodes for label-free or nanolabel-enhanced highly sensitive capacitive aptamer-based biosensors. Biosensors and Bioelectronics 164, S. 112272. Volltext nicht vorhanden.

Simon, Philipp , Busse, David , Petroff, David , Dorn, Christoph , Ehmann, Lisa, Hochstädt, Sophie, Girrbach, Felix, Dietrich, Arne, Zeitlinger, Markus, Kees, Frieder, Kloft, Charlotte und Wrigge, Hermann (2020) Linezolid Concentrations in Plasma and Subcutaneous Tissue are Reduced in Obese Patients, Resulting in a Higher Risk of Underdosing in Critically Ill Patients: A Controlled Clinical Pharmacokinetic Study. Journal of Clinical Medicine 9 (4), S. 1067.

Schießer, Selina, Hitzenbichler, Florian, Kees, Martin Georg, Kratzer, Alexander, Lubnow, Matthias , Salzberger, Bernd , Kees, Frieder und Dorn, Christoph (2020) Measurement of Free Plasma Concentrations of Beta-Lactam Antibiotics. Therapeutic Drug Monitoring Publ.Ahead. Volltext nicht vorhanden.

Simon, Philipp, Petroff, David, Busse, David , Heyne, Jana, Girrbach, Felix, Dietrich, Arne, Kratzer, Alexander Ludwig, Zeitlinger, Markus, Kloft, Charlotte, Kees, Frieder, Wrigge, Hermann und Dorn, Christoph (2020) Meropenem Plasma and Interstitial Soft Tissue Concentrations in Obese and Nonobese Patients—A Controlled Clinical Trial. Antibiotics 9 (12), S. 931.

Pontes de Sousa, Ingrid, Ferreira, Antônio Gilberto , Miller Crotti, Antônio Eduardo, Alves dos Santos, Raquel, Kiermaier, Josef, Kraus, Birgit, Heilmann, Jörg und Jacometti Cardoso Furtado, Niege Araçari (2020) New antifungal ent-labdane diterpenes against Candida glabrata produced by microbial transformation of ent-polyalthic acid. Bioorganic Chemistry 95, S. 103560. Volltext nicht vorhanden.

Konieczny, Adam, Braun, Diana, Wifling, David , Bernhardt, Günther und Keller, Max (2020) Oligopeptides as Neuropeptide Y Y4 Receptor Ligands: Identification of a High-Affinity Tetrapeptide Agonist and a Hexapeptide Antagonist. Journal of Medicinal Chemistry 63 (15), S. 8198-8215. Volltext nicht vorhanden.

Rustler, Karin , Gomila, Alexandre , Maleeva, Galyna, Gorostiza, Pau , Bregestovski, Piotr und König, Burkhard (2020) Optical Control of GABAA Receptors with a Fulgimide‐Based Potentiator. Chemistry - A European Journal 26, S. 12722-12727.

Rustler, Karin , Nitschke, Philipp, Zahnbrecher, Sophie, Zach, Julia, Crespi, Stefano und König, Burkhard (2020) Photochromic evaluation of 3(5)-arylazo-1H-pyrazoles. The Journal of Organic Chemistry 85, S. 4079-4088. Volltext nicht vorhanden.

Piacentino, Daria , Kotzalidis, Georgios D. , Schoretsanitis, Georgios , Paulzen, Michael, Haen, Ekkehard, Cappelletti, Simone, Giupponi, Giancarlo, Grözinger, Michael und Conca, Andreas (2020) Plasma Risperidone-related Measures in Children and Adolescents with Oppositional Defiant/Conduct Disorders. Clinical Psychopharmacology and Neuroscience 18 (1), S. 41-48. Volltext nicht vorhanden.

Thalhauser, Stefanie, Peterhoff, David, Wagner, Ralf und Breunig, Miriam (2020) Presentation of HIV-1 Envelope Trimers on the Surface of Silicia Nanoparticles. Journal of Pharmaceutical Sciences 109, S. 911-921. Volltext nicht vorhanden.

Busse, David , Simon, Philipp, Michelet, Robin , Ehmann, Lisa, Mehner, Frank, Dorn, Christoph , Kratzer, Alexander, Huisinga, Wilhelm, Wrigge, Hermann , Petroff, David und Kloft, Charlotte (2020) Quantification of microdialysis related variability in humans: Clinical trial design recommendations. European Journal of Pharmaceutical Sciences, S. 105607. Volltext nicht vorhanden.

She, Xueke, Pegoli, Andrea, Gruber, Corinna G., Wifling, David , Carpenter, Jessica, Hübner, Harald, Chen, Mengya, Wan, Jianfei, Bernhardt, Günther, Gmeiner, Peter , Holliday, Nicholas D. und Keller, Max (2020) Red-Emitting Dibenzodiazepinone Derivatives as Fluorescent Dualsteric Probes for the Muscarinic Acetylcholine M2 Receptor. Journal of Medicinal Chemistry 63 (8), S. 4133-4154. Volltext nicht vorhanden.

Ehmann, L., Simon, P., Busse, D., Petroff, D., Dorn, Christoph , Huisinga, W., Dietrich, A., Zeitlinger, M., Wrigge, H. und Kloft, C. (2020) Risk of target non-attainment In obese compared to non-obese patients In Calculated linezolid therapy. Clinical Microbiology and Infection. Volltext nicht vorhanden.

Thalhauser, Stefanie, Peterhoff, David, Wagner, Ralf und Breunig, Miriam (2020) Silica particles incorporated into PLGA-based in situ-forming implants exploit the dual advantage of sustained release and particulate delivery. European Journal of Pharmaceutics and Biopharmaceutics (156), S. 1-10. Volltext nicht vorhanden.

Stolwijk, Judith A., Mildner, Anne-Kathrin, Kade, Christian, Skiba, Michael, Bernhardt, Guenther, Buschauer, Armin, Huebner, Harald, Gmeiner, Peter und Wegener, Joachim (2020) Stepwise Dosing Protocol for Increased Throughput in Label-Free Impedance-Based GPCR Assays. Journal of Visualized Experiments (156). Volltext nicht vorhanden.

Fleischmann, Daniel, Maslanka-Figueroa, Sara und Göpferich, Achim (2020) Steric Shielding of cRGD-Functionalized Nanoparticles from Premature Exposition to Off-Target Endothelial Cells under a Physiological Flow. ACS Applied Bio Materials 4 (1), S. 640-650. Volltext nicht vorhanden.

Gienger, Marie, Hübner, Harald, Löber, Stefan, König, Burkhard und Gmeiner, Peter (2020) Structure-based development of caged dopamine D2/D3 receptor antagonists. Scientific Reports, S. 829.

Antoni, Frauke, Bause, Manuel, Scholler, Matthias, Bauer, Stefanie, Stark, Simone Alexandra, Jackson, Scott M., Manolaridis, Ioannis, Locher, Kaspar P., König, Burkhard , Buschauer, Armin und Bernhardt, Günther (2020) Tariquidar-related triazoles as potent, selective and stable inhibitors of ABCG2 (BCRP). European Journal of Medicinal Chemistry 191. Volltext nicht vorhanden.

Maslanka-Figueroa, Sara , Fleischmann, Daniel, Beck, Sebastian und Goepferich, Achim (2020) The Effect of Ligand Mobility on the Cellular Interaction of Multivalent Nanoparticles. Macromolecular Bioscience 20, S. 900427.

Kuzin, Maxim , Schoretsanitis, Georgios , Haen, Ekkehard, Dammann, Gerhard, Hiemke, Christoph, Gründer, Gerhard und Paulzen, Michael (2020) The Effects of Co-prescription of Pantoprazole on the Clozapine Metabolism. Pharmacopsychiatry 53 (02), S. 65-70. Volltext nicht vorhanden.

Maschauer, Simone, Ott, Julian J. , Bernhardt, Günther, Kuwert, Torsten, Keller, Max und Prante, Olaf (2019) 18F-labelled triazolyl-linked argininamides targeting the neuropeptide Y Y1R for PET Imaging of mammary carcinoma. Scientific Reports 9, S. 12990.

Schramm, Andrea, Schweda, Frank, Sequeira-Lopez, Maria Luisa S., Hofmann, Franz, Sandner, Peter und Schlossmann, Jens (2019) Protein Kinase G Is Involved in Acute but Not in Long-Term Regulation of Renin Secretion. Frontiers in Pharmacology 2019 (10), S. 800.

Dorn, Christoph, Petroff, David, Neumann, Nancy, Kratzer, Alexander, El-Najjar, Nahed , Dietrich, Arne, Kloft, Charlotte, Zeitlinger, Markus , Kees, Martin, Kees, Frieder, Wrigge, Hermann und Simon, Philipp (2019) Plasma and tissue pharmacokinetics of fosfomycin in morbidly obese and non-obese surgical patients: a controlled clinical trial. Journal of Antimicrobial Chemotherapy. Volltext nicht vorhanden.

Pegoli, Andrea, Wifling, David , Gruber, Corinna G., Xueke, She, Hübner, Harald, Bernhardt, Günther, Gmeiner, Peter und Keller, Max (2019) Conjugation of Short Peptides to Dibenzodiazepinone-Type
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Schindler, Lisa, Bernhardt, Günther und Keller, Max (2019) Modifications at Arg and Ile Give Neurotensin(8−13) Derivatives with High Stability and Retained NTS1 Receptor Affinity. ACS Medicinal Chemistry Letters 10 (6), S. 960-965. Volltext nicht vorhanden.

Kratzer, Alexander, Rothe, Ulrich, Kees, Frieder und Dorn, Christoph (2019) Stabilität von Ceftolozan/Tazobactam in Infusionslösungen für die verlängerte oder kontinuierliche Applikation. Krankenhauspharmazie 40 (4), S. 195-200. Volltext nicht vorhanden.

Pockes, Steffen, Wifling, David , Buschauer, Armin und Elz, Sigurd (2019) Structure‐Activity Relationship of Hetarylpropylguanidines Aiming at the Development of Selective Histamine Receptor Ligands †. ChemistryOpen 8 (3), S. 285-297.

Rustler, Karin , Pockes, Steffen und König, Burkhard (2019) Light-Switchable Antagonists for the Histamine H1 Receptor at the Isolated Guinea Pig Ileum. ChemMedChem 14 (6), S. 636-644. Volltext nicht vorhanden.

Schramm, Simon, Agnetta, Luca, Bermudez, Marcel, Gerwe, Hubert, Irmen, Matthias, Holze, Janine, Littmann, Timo, Wolber, Gerhard , Tränkle, Christian und Decker, Michael (2019) Novel BQCA‐ and TBPB‐Derived M 1 Receptor Hybrid Ligands: Orthosteric Carbachol Differentially Regulates Partial Agonism. ChemMedChem 14 (14), S. 1349-1358. Volltext nicht vorhanden.

Maleeva, Galyna , Wutz, Daniel, Rustler, Karin , Nin-Hill, Alba, Alfonso-Prieto, Mercedes , Petukhova, Elena , Bautista-Barrufet, Antoni, Gomila-Juaneda, Alexandre, Scholze, Petra , Peiretti, Franck, Rovira, Carme , König, Burkhard , Gorostiza, Pau und Bregestovski, Piotr (2019) A photoswitchable GABA receptor channel blocker. British Journal of Pharmacology 176, S. 2661-2677. Volltext nicht vorhanden.

Dechant, Franz-Xaver, Dechant, Rebecca, Kandulski, Arne, Selgrad, Michael, Weber, Florian, Reischl, Udo, Wilczek, Wolf, Mueller, Martina und Weigand, Kilian (2019) Accuracy of Different Rapid Urease Tests in Comparison with Histopathology in Patients with Endoscopic Signs of Gastritis. Digestion 101 (2), S. 184-190. Volltext nicht vorhanden.

Łażewska, Dorota , Mogilski, Szczepan, Hagenow, Stefanie , Kuder, Kamil, Głuch-Lutwin, Monika , Siwek, Agata , Więcek, Małgorzata, Kaleta, Maria, Seibel, Ulla, Buschauer, Armin, Filipek, Barbara, Stark, Holger und Kieć-Kononowicz, Katarzyna (2019) Alkyl derivatives of 1,3,5-triazine as histamine H4 receptor ligands. Bioorganic & Medicinal Chemistry 27 (7), S. 1254-1262. Volltext nicht vorhanden.

Polykandriotis, Elias, Horch, Raymund E., Jost, Matthias, Arkudas, Andreas, Kees, Frieder und Schmitz, Marweh (2019) Can systemically administered antibiotics be detected in wound tissues and surfaces under negative pressure wound therapy? International Wound Journal 16 (2), S. 503-510. Volltext nicht vorhanden.

Rustler, Karin , Pockes, Steffen und König, Burkhard (2019) Cover Feature: Light‐Switchable Antagonists for the Histamine H 1 Receptor at the Isolated Guinea Pig Ileum (ChemMedChem 6/2019). ChemMedChem 14 (6), S. 614. Volltext nicht vorhanden.

Kowalewski, Christoph, Haen, Ekkehard, Hiemke, Christoph, Ridders, Florian, Endres, Katharina, Gründer, Gerhard, Paulzen, Michael und Schoretsanitis, Georgios (2019) Cytochrome P450-mediated inhibition of venlafaxine metabolism by trimipramine. International Clinical Psychopharmacology 34 (5), S. 241-246. Volltext nicht vorhanden.

Dorn, Christoph , Kratzer, Alexander Ludwig, Schießer, Selina, Kees, Frieder , Wrigge, Hermann und Simon, Philipp (2019) Determination of total or free cefazolin and metronidazole in human plasma or interstitial fluid by HPLC-UV for pharmacokinetic studies in man. Journal of Chromatography B. Volltext nicht vorhanden.

Veselinović, Tanja, Scharpenberg, Martin, Heinze, Martin, Cordes, Joachim, Mühlbauer, Bernd, Juckel, Georg, Rüther, Eckart, Paulzen, Michael, Haen, Ekkehard, Hiemke, Christoph, Timm, Jürgen, Gründer, Gerhard, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference , make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference und make_name_string expected hash reference (2019) Dopamine D2 Receptor Occupancy Estimated From Plasma Concentrations of Four Different Antipsychotics and the Subjective Experience of Physical and Mental Well-Being in Schizophrenia. Journal of Clinical Psychopharmacology 39 (6), S. 550-560. Volltext nicht vorhanden.

Agnetta, Luca, Bermudez, Marcel , Riefolo, Fabio , Matera, Carlo , Claro, Enrique , Messerer, Regina, Littmann, Timo, Wolber, Gerhard , Holzgrabe, Ulrike und Decker, Michael (2019) Fluorination of Photoswitchable Muscarinic Agonists Tunes Receptor Pharmacology and Photochromic Properties. Journal of Medicinal Chemistry 62 (6), S. 3009-3020. Volltext nicht vorhanden.

Abstiens, Kathrin , Fleischmann, Daniel, Gregoritza, Manuel und Göpferich, Achim (2019) Gold-Tagged Polymeric Nanoparticles with Spatially Controlled Composition for Enhanced Detectability in Biological Environments. ACS Applied Nano Materials 2 (2), S. 917-926. Volltext nicht vorhanden.

Crespi, Stefano , Simeth, Nadja Anita und König, Burkhard (2019) Heteroaryl azo dyes as molecular photoswitches. Nature Reviews Chemistry 3, S. 133-146. Volltext nicht vorhanden.

Graf, Moritz, Ziegler, Christian, Gregoritza, Manuel und Goepferich, Achim (2019) Hydrogel microspheres evading alveolar macrophages for sustained pulmonary protein delivery. nternational Journal of Pharmaceutics 566, S. 652-661. Volltext nicht vorhanden.

Scharrenbroich, Jessica, Kaever, Volkhard, Dove, Stefan, Seifert, Roland und Schneider, Erich H. (2019) Hydrolysis of the non-canonical cyclic nucleotide cUMP by PDE9A: kinetics and binding mode. Naunyn-Schmiedeberg's Archives of Pharmacology 392 (2), S. 199-208. Volltext nicht vorhanden.

Stolwijk, J. A., Skiba, M., Kade, C., Bernhardt, G., Buschauer, Armin , Hübner, H., Gmeiner, P. und Wegener, Joachim (2019) Increasing the throughput of label-free cell assays to study the activation of G-protein-coupled receptors by using a serial agonist exposure protocol. Integrative Biology 11 (3), S. 99-108. Volltext nicht vorhanden.

Maslanka-Figueroa, Sara, Veser, Anika, Abstiens, Kathrin, Fleischmann, Daniel und Göpferich, Achim (2019) Influenza A virus mimetic nanoparticles trigger selective cell uptake. PNAS 116 (20), S. 9831-9836. Volltext nicht vorhanden.

Gergs, U. , Bernhardt, Günther, Buchwalow, I. B., Edler, H., Fröba, J., Keller, Max, Kirchhefer, U., Köhler, F., Mißlinger, N., Wache, H. und Neumann, J. (2019) Initial Characterization of Transgenic Mice Overexpressing Human Histamine H2 Receptors. Journal of Pharmacology and Experimental Therapeutics 369 (1), S. 129-141. Volltext nicht vorhanden.

Bohley, Marilena, Haunberger, Alexandra und Göpferich, Achim (2019) Intracellular availability of poorly soluble drugs from lipid nanocapsules. European Journal of Pharmaceutics and Biopharmaceutics 139, S. 23-32. Volltext nicht vorhanden.

Nussbaumer-Pröll, Alina Karoline, Eberl, Sabine, Reiter, Birgit, Stimpfl, Thomas, Dorn, Christoph und Zeitlinger, Markus (2019) Low pH reduces the activity of ceftolozane/tazobactam in human urine, but confirms current breakpoints for urinary tract infections. Journal of Antimicrobial Chemotherapy. Volltext nicht vorhanden.

Simon, P., Petroff, D., Dorn, Christoph , Ehmann, L., Kloft, C., Prettin, C., Dietrich, A., Zeitlinger, M., Kees, F. und Wrigge, H. (2019) Measurement of soft tissue drug concentrations in morbidly obese and non-obese patients – A prospective, parallel group, open-labeled, controlled, phase IV, single center clinical trial. Contemporary Clinical Trials Communications 15, S. 100375. Volltext nicht vorhanden.

Abstiens, Kathrin und Göpferich, Achim (2019) Microfluidic manufacturing improves polydispersity of multicomponent polymeric nanoparticles. Journal of Drug Delivery Science and Technology 49, S. 433-439. Volltext nicht vorhanden.

Wimmer, Alexander und König, Burkhard (2019) N‑Arylation of NH-Sulfoximines via Dual Nickel Photocatalysis. Organic Letters 21, S. 2740-2744.

Schoretsanitis, Georgios , Haen, Ekkehard, Hiemke, Christoph, Endres, Katharina, Ridders, Florian, Veselinovic, Tanja, Gründer, Gerhard und Paulzen, Michael (2019) Pharmacokinetic correlates of venlafaxine: associated adverse reactions. European Archives of Psychiatry and Clinical Neuroscience 269 (7), S. 851-857. Volltext nicht vorhanden.

Lachmann, Daniel, Konieczny, Adam, Keller, Max und König, Burkhard (2019) Photochromic peptidic NPY Y4-receptor ligands. Organic & Biomolecular Chemistry 17, S. 2467-2478. Volltext nicht vorhanden.

Heider, Fabian , Ansideri, Francesco, Tesch, Roberta, Pantsar, Tatu, Haun, Urs, Döring, Eva, Kudolo, Mark, Poso, Antti , Albrecht, Wolfgang, Laufer, Stefan A. und Koch, Pierre (2019) Pyridinylimidazoles as dual glycogen synthase kinase 3β/p38α mitogen-activated protein kinase inhibitors. European Journal of Medicinal Chemistry 175, S. 309-329. Volltext nicht vorhanden.

Nowak, Hartmuth, Weidemann, Caroline, Martini, Stefan, Oesterreicher, Zoe Anne, Dorn, Christoph, Adamzik, Michael, Kees, Frieder, Zeitlinger, Markus und Rahmel, Tim (2019) Repeated determination of moxifloxacin concentrations in interstitial space fluid of muscle and subcutis in septic patients. Journal of Antimicrobial Chemotherapy. Volltext nicht vorhanden.

Schwindl, Sebastian, Kraus, Birgit und Heilmann, Jörg (2019) Secondary metabolites from the leaves of Juglans regia L. Biochemical Systematics and Ecology 83, S. 130-136. Volltext nicht vorhanden.

Soliman, Beatrice, Wang, Ning, Zagotto, Giuseppe und Pockes, Steffen (2019) Synthesis and biological evaluation of heteroalicyclic cyanoguanidines at histamine receptors. Archiv der Pharmazie 352 (9), S. 1900107. Volltext nicht vorhanden.

Abstiens, Kathrin , Gregoritza, Manuel und Goepferich, Achim (2018) Ligand Density and Linker Length are Critical Factors for Multivalent Nanoparticle−Receptor Interactions. ACS Applied Materials & Interfaces 11 (1), S. 1311-1320. Volltext nicht vorhanden.

Makule, Edna E., Kraus, Birgit, Jürgenliemk, Guido, Heilmann, Jörg und Wiesneth, Stefan (2018) Dioic acid glycosides, tannins and methylated ellagic acid glycosides from Morella salicifolia bark. Phytochemistry Letters 28, S. 76-83. Volltext nicht vorhanden.

Gregoritza, Manuel (2018) Click Hydrogels for Controlled Local Antibody Delivery. Dissertation, Universität Regensburg.

Littmann, Timo, Ozawa, Takeaki, Hoffmann, Carsten, Buschauer, Armin und Bernhardt, Günther (2018) A split luciferase-based probe for quantitative proximal determination of Gαq signalling in live cells. Scientific Reports 8 (17179), S. 1-10.

Kratzer, Alexander, Schießer, Selina, Matzneller, Peter, Wulkersdorfer, Beatrix, Zeitlinger, Markus , Schlossmann, Jens , Kees, Frieder und Dorn, Christoph (2018) Determination of Total and Free Ceftolozane and Tazobactam in Human Plasma and Interstitial Fluid by HPLC-UV. Journal of Pharmaceutical and Biomedical Analysis. Volltext nicht vorhanden.

Köhler, Julia (2018) Hydrogel Wound Dressings for the Bioactive Treatment of Acute and Chronic Wounds. Dissertation, Universität Regensburg.

Walz, Johanna Madeleine (2018) VEGF-Inhibition bei der Frühgeborenenretinopathie
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Keil, Stefanie-Klara (2018) Evaluation der massenspektrometrischen Analyse von Serumgallensäuren in der Differentialdiagnostik (cholestatischer) Lebererkrankungen im Kindes- und Jugendalter und zum therapeutischen Drug Monitoring
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Böhr, Sebastian (2018) Therapeutisches Drug Monitoring der direkten oralen Antikoagulanzien. Dissertation, Universität Regensburg.

Yang, Zhenlin, Han, Shuo, Keller, Max, Kaiser, Anette, Bender, Brain J., Bosse, Mathias, Burkert, Kerstin, Kögler, Lisa M., Wifling, David , Bernhardt, Günther, Plank, Nicole, Littmann, Timo, Schmidt, Peter, Yi, Cuiying, Li, Beibei, Ye, Sheng, Zhang, Rongguang, Xu, Bo, Larhammar, Dan, Stevens, Raymond C. , Huster, Daniel, Meiler, Jens, Zhao, Qiang, Beck-Sickinger, Annette G., Buschauer, Armin und Wu, Beili (2018) Structural basis of ligand binding modes at the
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Schramm, Andrea, Mueller-Thuemen, Philip, Littmann, Timo, Harloff, Manuela, Ozawa, Takeaki und Schlossmann, Jens (2018) Establishing a Split Luciferase Assay for Proteinkinase G (PKG) Interaction Studies. International Journal o f Molecular Sciences 19 (4), S. 1180.

Mayer, Larissa Joyce (2018) Effekte einer konsekutiven Aktivierung des MAP-Kinase-Signalwegs in humanen Melanozyten. Dissertation, Universität Regensburg.

Pockes, Steffen , Wifling, David , Keller, Max, Buschauer, Armin und Elz, Sigurd (2018) Highly Potent, Stable, and Selective Dimeric Hetarylpropylguanidine-Type Histamine H2 Receptor Agonists. ACS Omega 2018 (3), S. 2865-2882.

Makule, Edna (2018) Ethnopharmacological survey and phytochemical investigation of Maasai traditional medicinal plants from north-eastern Tanzania. Dissertation, Universität Regensburg.

Volkov, Ilya B. (2018) Phytochemical and pharmacological study
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Pockes, Steffen (2018) Synthese und pharmakologische Charakterisierung von Heteroarylpropylguanidin-Derivaten an Histamin-Rezeptorsubtypen: Struktur-Wirkungsbeziehungen mono- und bivalenter Liganden. Dissertation, Universität Regensburg.

Dietrich, Peter, Kuphal, Silke, Spruss, Thilo, Hellerbrand, Claus und Bosserhoff, Anja K. (2018) Micro RNA ‐622 is a novel mediator of tumorigenicity in melanoma by targeting Kirsten rat sarcoma. Pigment Cell & Melanoma Research 31 (5), S. 614-629. Volltext nicht vorhanden.

Littmann, Timo, Ozawa, Takeaki, Hoffmann, Carsten, Buschauer, Armin und Bernhardt, Günther (2018) A split luciferase-based probe for quantitative proximal determination of Gαq signalling in live cells. Scientific Reports 8 (1), S. 17179.

Walz, J. M., Bemme, S., Reichl, S., Akman, S., Breuß, H., Süsskind, D., Glitz, B., Müller, V. C., Wagenfeld, L., Gabel-Pfisterer, A., Aisenbrey, S., Engelmann, K., Koutsonas, A., Krohne, T. U. und Stahl, A. (2018) Behandelte Frühgeborenenretinopathie in Deutschland. Der Ophthalmologe 115 (6), S. 476-488. Volltext nicht vorhanden.

Schmidberger, Andreas, Schupfner, Robert und Matysik, Frank-Michael (2018) Development of an analytical strategy for the determination of 228Th and 232Th in ivory based on the combined use of ICP-MS and α-spectrometry. Journal of Radioanalytical and Nuclear Chemistry 318 (3), S. 2007-2011. Volltext nicht vorhanden.

Koehler, Julia, Brandl, Ferdinand und Goepferich, Achim (2018) Hydrogel wound dressing for bioactive treatment of acute and chronic wounds. European Polymer Journal 100, S. 1-11. Volltext nicht vorhanden.

Dorn, Christoph, Kratzer, Alexander, Liebchen, Uwe, Schleibinger, Michael, Murschhauser, Alexandra, Schlossmann, Jens , Kees, Frieder, Simon, Philipp und Kees, Martin G. (2018) Impact of Experimental Variables on the Protein Binding of Tigecycline in Human Plasma as Determined by Ultrafiltration. Journal of Pharmaceutical Sciences 107 (2), S. 739-744. Volltext nicht vorhanden.

Dillinger, Andrea E., Guter, Michaela, Froemel, Franziska, Weber, Gregor R., Perkumas, Kristin, Stamer, W. Daniel, Ohlmann, Andreas, Fuchshofer, Rudolf und Breunig, Miriam (2018) Intracameral Delivery of Layer‐by‐Layer Coated siRNA Nanoparticles for Glaucoma Therapy. Small 14 (50), S. 1803239. Volltext nicht vorhanden.

Wiesneth, Stefan, Aas, Gregor, Heilmann, Jörg und Jürgenliemk, Guido (2018) Investigation of the flavan-3-ol patterns in willow species during one growing-season. Phytochemistry 145, S. 26-39. Volltext nicht vorhanden.

Thamm, M. , Sturm, K., Schlossmann, J. und Scheiner, R. (2018) Levels and activity of cyclic guanosine monophosphate-dependent protein kinase in nurse and forager honeybees. Insect Molecular Biology 27 (6), S. 815-823. Volltext nicht vorhanden.

Sellmer, Andreas, Stangl, Hubert, Beyer, Mandy, Grünstein, Elisabeth, Leonhardt, Michel, Pongratz, Herwig, Eichhorn, Emerich, Elz, Sigurd, Striegl, Birgit, Jenei-Lanzl, Zsuzsa, Dove, Stefan, Straub, Rainer H., Krämer, Oliver H. und Mahboobi, Siavosh (2018) Marbostat-100 Defines a New Class of Potent and Selective Antiinflammatory and Antirheumatic Histone Deacetylase 6 Inhibitors. Journal of Medicinal Chemistry 61 (8), S. 3454-3477. Volltext nicht vorhanden.

Chuskit, Deachen, Chaudhary, Renu, Venugopalan, Paloth, König, Burkhard und Natarajan, Palani (2018) Oxidative homodimerization of substituted olefins by DDQ visible light photocatalysis. Organic Chemistry Frontiers 5, S. 3553-3556. Volltext nicht vorhanden.

Schoretsanitis, Georgios, de Leon, Jose, Haen, Ekkehard, Stegmann, Benedikt, Hiemke, Christoph, Gründer, Gerhard und Paulzen, Michael (2018) Pharmacokinetics of risperidone in different application forms – Comparing long-acting injectable and oral formulations. European Neuropsychopharmacology 28 (1), S. 130-137. Volltext nicht vorhanden.

Mathioudaki, Angeliki, Berzesta, Ariola, Kypriotakis, Zacharias, Skaltsa, Helen und Heilmann, Jörg (2018) Phenolic metabolites from Hypericum kelleri Bald., an endemic species of Crete (Greece). Phytochemistry 146, S. 1-7. Volltext nicht vorhanden.

Paolillo, Michael , Peters, Stefanie, Schramm, Andrea, Schlossmann, Jens und Feil, Robert (2018) Real-Time Imaging Reveals Augmentation of Glutamate-Induced Ca2+ Transients by the NO-cGMP Pathway in Cerebellar Granule Neurons. International Journal of Molecular Sciences 19, S. 2185.

Jackson, Scott M., Manolaridis, Ioannis, Kowal, Julia , Zechner, Melanie, Taylor, Nicholas M. I. , Bause, Manuel, Bauer, Stefanie, Bartholomaeus, Ruben, Bernhardt, Günther, König, Burkhard , Buschauer, Armin, Stahlberg, Henning , Altmann, Karl-Heinz und Locher, Kaspar P. (2018) Structural basis of small-molecule inhibition of human multidrug transporter ABCG2. Nature Structural & Molecular Biology 25 (4), S. 333-340. Volltext nicht vorhanden.

Dolles, Dominik, Hoffmann, Matthias, Gunesch, Sandra, Marinelli, Oliviero, Möller, Jan , Santoni, Giorgio, Chatonnet, Arnaud, Lohse, Martin J. , Wittmann, Hans-Joachim, Strasser, Andrea, Nabissi, Massimo, Maurice, Tangui und Decker, Michael (2018) Structure–Activity Relationships and Computational Investigations into the Development of Potent and Balanced Dual-Acting Butyrylcholinesterase Inhibitors and Human Cannabinoid Receptor 2 Ligands with Pro-Cognitive in Vivo Profiles. Journal of Medicinal Chemistry 61 (4), S. 1646-1663. Volltext nicht vorhanden.

Plokhikh, I. V. , Charkin, D. O., Verchenko, V. Yu., Kuznetsov, A. N., Tsirlin, A. A., Kazakov, S. M. und Shevelkov, A. V. (2018) Synthesis, crystal structure and physical properties of europium – manganese fluoride pnictides, EuMnPnF (Pn = P, As, Sb). Journal of Solid State Chemistry 258, S. 682-690. Volltext nicht vorhanden.

Peña-Solórzano, Diana, Scholler, Matthias, Bernhardt, Günther, Buschauer, Armin , König, Burkhard und Ochoa-Puentes, Cristian (2018) Tariquidar-Related Chalcones and Ketones as ABCG2 Modulators. ACS Medicinal Chemistry Letters 9, S. 854-859. Volltext nicht vorhanden.

Uchida, Hitoshi, Matsumura, Shinji, Katano, Tayo, Watanabe, Masahiko , Schlossmann, Jens und Ito, Seiji (2018) Two isoforms of cyclic GMP-dependent kinase-I exhibit distinct expression patterns in the adult mouse dorsal root ganglion. Molecular Pain 14, S. 174480691879640. Volltext nicht vorhanden.

Brosig, Andreas Michael (2017) Technical comparison of four different extracorporeal photopheresis systems. Dissertation, Universität Regensburg.

Chen, Kang, Berg, Nele, Gschwind, Ruth Maria und König, Burkhard (2017) Selective Single C(sp3)−F Bond Cleavage in Trifluoromethylarenes: Merging Visible-Light Catalysis with Lewis Acid Activation. Journal of the American Chemical Society 139, S. 18444-18447. Volltext nicht vorhanden.

She, Xueke, Pegoli, Andrea, Mayr, Judith, Hübner, Harald, Bernhardt, Günther , Gmeiner, Peter und Keller, Max (2017) Heterodimerization of Dibenzodiazepinone-Type Muscarinic Acetylcholine Receptor Ligands Leads to Increased M2R Affinity and Selectivity. ACS Omega 2 (10), S. 6741-6754.

Kuhn, Kilian (2017) Molecular Tools for the NPY Y₄ Receptor Derived from the C-Terminus of hPP and from Argininamide-type Y₁R Antagonists. Dissertation, Universität Regensburg.

Oswald, Mira (2017) Targeted CNS Delivery via Nanoparticulate Drug Delivery Systems. Dissertation, Universität Regensburg.

Wetzl, Veronika (2017) Fibrose-assoziierte Biomarker – Einfluss der Behandlung mit Serelaxin im murinen Nierenfibrose-Modell und prädiktiver Aussagewert in der pulmonalen Hypertonie. Dissertation, Universität Regensburg.

Scheck, Luisa (2017) Characterization of TSPO 18 kDa in neurosteroid synthesis and mitochondrial metabolism. Dissertation, Universität Regensburg.

Endres, Wolfgang (2017) Reparier Dich Selbst! Working Paper. (Eingereicht) Zugang zum Volltext eingeschränkt.

Hammer, Nadine (2017) Hydrogels for the Controlled Release of Protein Pharmaceuticals. Dissertation, Universität Regensburg.

Strasser, Andrea, Wittmann, Hans-Joachim und Seifert, Roland (2017) Binding kinetics and pathways of ligands to GPCRs. Trends in Pharmacological Sciences. (Im Druck) Volltext nicht vorhanden.

Dessauer, Carmen W., Watts, Val J., Ostrom, Rennolds S., Conti, Marco, Dove, Stefan und Seifert, Roland (2017) International Union of Basic and Clinical Pharmacology. CI. Structures and Small Molecule Modulators of Mammalian Adenylyl Cyclases. Pharmacological Reviews 69 (2), S. 93-139. Volltext nicht vorhanden.

Wiesneth, Stefan, Aas, Gregor, Heilmann, Jörg und Jürgenliemk, Guido (2017) Comparative investigation of the flavan-3-ol patterns in two willows during one growing season. In: International PhD students/Postdocs meeting of the German Pharmaceutical Society (DPhG), 29.-31. März 2017, Frankfurt am Main, Germany. Volltext nicht vorhanden.

Schlossmann, Jens, Schinner, Elisabeth, Wetzl, Veronika, Schramm, Andrea, Kees, Frieder, Sandner, Peter, Stasch, Johannes-Peter und Hofmann, Franz (2017) Inhibition of the TGFβ signalling pathway by cGMP and cGMP‐dependent kinase I in renal fibrosis. FEBS openbio 7 (4), S. 550-561.

Wittmann, Hans-Joachim und Strasser, Andrea (2017) Competitive association binding kinetic assays: a new tool to detect two different binding orientations of a ligand to its target protein under distinct conditions? Naunyn-Schmiedeberg's Archives of Pharmacology. (Im Druck) Volltext nicht vorhanden.

Dorn, Christoph , Nowak, Hartmuth, Weidemann, Caroline, Martini, Stefan, Zeitlinger, Markus, Adamzik, Michael und Kees, Frieder K. (2017) Decreased protein binding of moxifloxacin in patients with sepsis? GMS Infectious Diseases 2017 (5), Doc03.

Koehler, Julia, Verheyen, Leonie, Hedtrich, Sarah, Brandl, Ferdinand P. und Goepferich, Achim M. (2017) Alkaline poly(ethylene glycol)-based hydrogels for a potential use as bioactive wound dressings. Journal of Biomedical Materials Research Part A 105 (12), S. 3360-3368. Volltext nicht vorhanden.

Schäfer, Claudia, Göder, Anja, Beyer, Mandy, Kiweler, Nicole, Mahendrarajah, Nisintha, Rauch, Anke, Nikolova, Teodora, Stojanovic, Natasa, Wieczorek, Martin, Reich, Thomas R., Tomicic, Maja T., Linnebacher, Michael, Sonnemann, Jürgen, Dietrich, Sascha, Sellmer, Andreas, Mahboobi, Siavosh, Heinzel, Thorsten, Schneider, Günter und Krämer, Oliver H. (2017) Class I histone deacetylases regulate p53/NF-κB crosstalk in cancer cells. Cellular Signalling 29, S. 218-225. Volltext nicht vorhanden.

Gregoritza, Manuel , Messmann, Viktoria, Abstiens, Kathrin, Brandl, Ferdinand und Göpferich, Achim (2017) Controlled Antibody Release from Degradable Thermoresponsive
Hydrogels Cross-Linked by Diels−Alder Chemistry.
Biomacromolecules 18, S. 2410-2418. Volltext nicht vorhanden.

Makule, Edna, Schmidt, Thomas J. , Heilmann, Jörg und Kraus, Birgit (2017) Diarylheptanoid Glycosides of Morella salicifolia Bark. Molecules 22, S. 2266.

Stojanovic, N., Hassan, Z., Wirth, M., Wenzel, P., Beyer, M., Schäfer, C., Brand, P., Kroemer, A., Stauber, R. H., Schmid, R. M., Arlt, A., Sellmer, A., Mahboobi, S., Rad, R., Reichert, M., Saur, D., Krämer, O. H. und Schneider, G. (2017) HDAC1 and HDAC2 integrate the expression of p53 mutants in pancreatic cancer. Oncogene 36 (13), S. 1804-1815. Volltext nicht vorhanden.

Mahendrarajah, Nisintha, Borisova, Marina E., Reichardt, Sigrid, Godmann, Maren, Sellmer, Andreas, Mahboobi, Siavosh, Haitel, Andrea, Schmid, Katharina, Kenner, Lukas , Heinzel, Thorsten, Beli, Petra und Krämer, Oliver H. (2017) HSP90 is necessary for the ACK1-dependent phosphorylation of STAT1 and STAT3. Cellular Signalling 39, S. 9-17. Volltext nicht vorhanden.

Guter, Michaela und Breunig, Miriam (2017) Hyaluronan as a promising excipient for ocular drug delivery. European Journal of Pharmaceutics and Biopharmaceutics 113, S. 34-49. Volltext nicht vorhanden.

Kuhn, Kilian K., Littmann, Timo, Dukorn, Stefanie, Tanaka, Miho, Keller, Max, Ozawa, Takeaki, Bernhardt, Günther und Buschauer, Armin (2017) In Search of NPY Y4R Antagonists: Incorporation of Carbamoylated Arginine, Aza-Amino Acids, or d-Amino Acids into Oligopeptides Derived from the C-Termini of the Endogenous Agonists. ACS Omega 2 (7), S. 3616-3631.

Ittner, Karl, Koppenberg, Joachim und Walter, Ute (2017) Indikationsfremde Anwendung von Medikamenten und Medizinprodukten in der Notfallmedizin. Der Notarzt 33 (04), S. 178-188. Volltext nicht vorhanden.

Slattery, David A., Neumann, Inga D., Flor, Peter J. und Zoicas, Iulia (2017) Pharmacological modulation of metabotropic glutamate receptor subtype 5 and 7 impairs extinction of social fear in a time-point-dependent manner. Behavioural Brain Research 328, S. 57-61. Volltext nicht vorhanden.

Wutz, Daniel-Fabian, Gluhacevic, Dino, Chakrabarti, A., Schmidtkunz, K., Robaa, D., Erdmann, F., Romier, C., Sippl, W., Jung, M. und König, Burkhard (2017) Photochromic histone deacetylase inhibitors based on
dithienylethenes and fulgimides.
Organic & Biomolecular Chemistry 15, S. 4882-4896. Volltext nicht vorhanden.

Backofen, Michael, Schwach, Gregoire, Koechling, Wolfgang, Weiss, Torsten und Goepferich, Achim (2017) Polyanion based controlled release system for the GnRH-receptor antagonist degarelix. European Journal of Pharmaceutical Sciences 104, S. 65-71. Volltext nicht vorhanden.

Tomasetti, Luise und Breunig, Miriam (2017) Preventing Obstructions of Nanosized Drug Delivery
Systems by the Extracellular Matrix.
Advanced Healthcare Materials, S. 1-16. Volltext nicht vorhanden.

Pegoli, Andrea , She, Xueke, Wifling, David , Hübner, Harald, Bernhardt, Günther, Gmeiner, Peter und Keller, Max (2017) Radiolabeled Dibenzodiazepinone-Type Antagonists Give Evidence of Dualsteric Binding at the M2 Muscarinic Acetylcholine Receptor. Journal of Medicinal Chemistry 60 (8), S. 3314-3334. Volltext nicht vorhanden.

Meyer, Andreas Uwe , Wimmer, Alexander und König, Burkhard (2017) Visible-Light-Accelerated C−H Sulfinylation of Heteroarenes. Angewandte Chemie International Edition 56, S. 409-412. Volltext nicht vorhanden.

Onuoha, Mary Remigius Agatha (2016) Therapeutic Drug Monitoring of Antipsychotics - HPLC Analytical Method Development and Pharmaceutical Advices to the Ward Clinicians - For Successful Individualized Therapy. Dissertation, Universität Regensburg.

Strasser, Andrea und Wittmann, Hans-Joachim (2016) Molecular Modelling Approaches for the Analysis of Histamine Receptors and Their Interaction with Ligands. In: Handbook of Experimental Pharmacology. (Im Druck) Volltext nicht vorhanden.

Lieb, Sebastian (2016) Investigations on histamine and neuropeptide Y receptors by label-free and label-dependent methods. Dissertation, Universität Regensburg.

Lieb, Sebastian, Littmann, Timo, Plank, Nicole, Felixberger, Johannes, Tanaka, Miho, Schäfer, Thorsten, Krief, Stéphane, Elz, Sigurd, Friedland, Kristina, Bernhardt, Günther, Wegener, Joachim, Ozawa, Takeaki und Buschauer, Armin (2016) Label-free versus conventional cellular assays: functional investigations on the human histamine H1 receptor. Pharmacological Research 114, S. 13-26. Volltext nicht vorhanden.

Wiesneth, Stefan, Heilmann, Jörg und Jürgenliemk, Guido (2016) Total phenolic and tannins determination: A modification of Ph. Eur. 2.8.14 suitable for high-throughput screenings. In: Annual Meeting of the German Pharmaceutical Society (DPhG), 4.-7. Okt. 2016, München, Germany. Volltext nicht vorhanden.

Sadek, Bassem, Khan, Nadia, Darras, Fouad H., Pockes, Steffen und Decker, Michael (2016) The dual-acting AChE inhibitor and H3 receptor antagonist UW-MD-72 reverses amnesia induced by scopolamine or dizocilpine in passive avoidance paradigm in rats. Physiology & Behavior 165, S. 383-391. Volltext nicht vorhanden.

Töpper, Christoph, Steinbach, Cathérine Louise, Dorn, Christoph , Kratzer, Alexander, Wicha, Sebastian G., Schleibinger, Michael, Liebchen, Uwe, Kees, Frieder, Salzberger, Bernd und Kees, Martin G. (2016) Variable linezolid exposure in ICU patients—possible role of drug-drug interactions. Therapeutic Drug Monitoring 38 (5), S. 573-578. Volltext nicht vorhanden.

Naporra, Franziska, Gobleder, Susanne, Wittmann, Hans-Joachim, Spindler, Julia, Bodensteiner, Michael, Bernhardt, Günther, Hübner, Harald, Gmeiner, Peter, Elz, Sigurd und Strasser, Andrea (2016) Dibenzo[b,f][1,4]oxazepines and dibenzo[b,e]oxepines: Influence of the chlorine substitution pattern on the pharmacology at the H1R, H4R, 5-HT2AR and other selected GPCRs. Pharmacological Research 113, S. 610-625. (Im Druck) Volltext nicht vorhanden.

Kunath, Julia (2016) Designermoleküle hemmen die Semaphorin 3F Wirkung in vitro, haben aber keinen Einfluss auf den Verlauf der experimentellen Arthritis. Dissertation, Universität Regensburg.

Untergehrer, Monika (2016) Analytische Untersuchungen zu phenolischen Inhaltsstoffen aus Salicis Cortex unter besonderer Berücksichtigung ihrer Metabolisierung. Dissertation, Universität Regensburg.

Schlossmann, Jens, Wetzl, Veronika, Schinner, Elisabeth, Kees, Frieder K., Hofmann, Franz und Faerber, Lothar (2016) Involvement of cyclic guanosine monophosphate-dependent protein kinase I in renal antifibrotic effects of serelaxin. Frontiers in Pharmacology 7 (195), S. 1-27.

Hennig, Robert (2016) Multivalent nanoparticles for the treatment of ocular diseases. Dissertation, Universität Regensburg.

Wurster, Eva-Christina (2016) Layer-by-Layer assembled thin films for drug delivery: Interactions at the nano-bio interface. Dissertation, Universität Regensburg.

Korber, Nikolaus und Friedrich, Ute (2016) A Step in Between: [Sn3Bi3]5− and Its Structural Relationship to [Sn3Bi5]3− and [Sn4Bi4]4−. Chemistry Open 5 (4), S. 306-310.

Kuhn, Kilian K., Ertl, Thomas, Dukorn, Stefanie, Keller, Max, Bernhardt, Günther, Reiser, Oliver und Buschauer, Armin (2016) High affinity agonists of the neuropeptide Y (NPY) Y4 receptor derived from the C-terminal pentapeptide of human pancreatic polypeptide (hPP): synthesis, stereochemical discrimination and radiolabeling. Journal of Medicinal Chemistry 59 (13), S. 6045-6058. Volltext nicht vorhanden.

Gobleder, Susanne (2016) Synthesis and pharmacological characterization of new histamine H1-/H4-receptor ligands derived from the atypical antipsychotic drug Clozapine. Dissertation, Universität Regensburg.

Wiesneth, Stefan (2016) Polyphenole aus Salix – Neue Teile im phytochemischen Puzzle (Polyphenols from Salix – new insights into the phytochemical composition). In: 3. Doktorandenkolleg der WALA Heilmittel GmbH (PhD students meeting), 30. April 2016, Bad Boll / Eckwälden, Germany. Volltext nicht vorhanden.

Kratzer, Alexander Ludwig (2016) Entwicklung und Erprobung von HPLC-basierten Methoden für das Therapeutische Drug-Monitoring von Betalaktam-Antibiotika, Linezolid und Tigecyclin – Bestimmung von freien und totalen Konzentrationen im Plasma von Intensivpatienten. Dissertation, Universität Regensburg.

Geyer, Roland, Nordemann, Uwe, Strasser, Andrea, Wittmann, Hans-Joachim und Buschauer, Armin (2016) Conformational restriction and enantioseparation increase potency and selectivity of cyanoguanidine-type histamine H4 receptor agonists. Journal of Medicinal Chemistry 59 (7), S. 3452-3470. Volltext nicht vorhanden.

Huber, Stefan (2016) Investigations on bendamustine esters as new antitumor agents and the role of ABCG2 as a surrogate marker of breast cancer initiating cells. Dissertation, Universität Regensburg.

Limmer, Franziska (2016) Funktionelle Analyse der cGMP-abhängigen Proteinkinase I in der Niere, insbesondere im dicken aufsteigenden Ast der Henle-Schleife. Dissertation, Universität Regensburg.

Edalat, Lena, Stegen, Benjamin, Klumpp, Lukas, Haehl, Erik, Schilbach, Karin, Lukowski, Robert, Kühnle, Matthias, Bernhardt, Günther, Buschauer, Armin, Zips, Daniel, Ruth, Peter und Huber, Stephan M. (2016) BK K+ channel blockade inhibits radiation-induced migration/brain infiltration of glioblastoma cells. Oncotarget 7 (12), S. 14259-14278. Volltext nicht vorhanden.

Felixberger, Johannes (2016) Luciferase complementation for the determination of arrestin recruitment: Investigations at histamine and NPY receptors. Dissertation, Universität Regensburg.

Stangl, Hubert Werner (2016) Arthritis and cholinergic transition of sympathetic nerve fibers. Dissertation, Universität Regensburg.

Vögeler, Jessica (2016) Pharmakotherapie und Humanpharmakologische Untersuchungen bei Patienten mit DME (Diabetisches Makulaödem) und PDR (Proliferative Diabetische Retinopathie) anhand klinischer Parameter und inflammatorischer Biomarker. Dissertation, Universität Regensburg.

Lorenz, Peter, Knittel, Diana N., Conrad, Jürgen, Lotter, Eva M., Heilmann, Jörg, Stintzing, Florian C. und Kammerer, Dietmar R. (2016) 1-Acetyl-3-[(3R)-hydroxyfatty acyl]glycerols: Lipid Compounds fromEuphrasia rostkovianaHayneandE. tetraquetra(Bréb.)Arrond. Chemistry & Biodiversity 13 (5), S. 602-612. Volltext nicht vorhanden.

Hammer, Sebastian, Gobleder, Susanne, Naporra, Franziska, Wittmann, Hans-Joachim, Elz, Sigurd, Heinrich, Markus und Strasser, Andrea (2016) 2,4-Diaminopyrimidines as dual ligands at the histamine H1 and H4 receptor - H1/H4-receptor selectivity. Bioorganic & Medicinal Chemistry Letters 26, S. 292-300. Volltext nicht vorhanden.

Dolles, Dominik, Nimczick, Martin, Scheiner, Matthias, Ramler, Jacqueline, Stadtmüller, Patricia, Sawatzky, Edgar, Drakopoulos, Antonios, Sotriffer, Christoph, Wittmann, Hans-Joachim, Strasser, Andrea und Decker, Michael (2016) Aminobenzimidazoles and structural isomers as templates for dual-acting butyrylcholinesterase inhibitors and hCB2R ligands to combat neurodegenerative disorders. ChemMedChem 11 (12), S. 1270-1283. Volltext nicht vorhanden.

Bucher, Felicitas , Walz, Johanna M., Bühler, Anima, Aguilar, Edith, Lange, Clemens, Diaz-Aguilar, Sophia, Martin, Gottfried, Schlunck, Günther, Agostini, Hansjürgen, Friedlander, Martin und Stahl, Andreas (2016) CNTF Attenuates Vasoproliferative Changes Through Upregulation of SOCS3 in a Mouse-Model of Oxygen-Induced Retinopathy. Investigative Opthalmology & Visual Science 57 (10), S. 4017. Volltext nicht vorhanden.

Hennig, Robert, Kuespert, Sabrina, Haunberger, Alexandra, Goepferich, Achim und Fuchshofer, Rudolf (2016) Cyclic RGD peptides target human trabecular meshwork cells while ameliorating connective tissue growth factor-induced fibrosis. Journal of Drug Targeting 24 (10), S. 952-959. Volltext nicht vorhanden.

Gregoritza, Manuel, Messmann, Viktoria, Goepferich, Achim und Brandl, Ferdinand (2016) Design of hydrogels for delayed antibody release utilizing hydrophobic association and Diels-Alder chemistry in tandem. Journal of Materials Chemistry B 4 (19), S. 3398-3408. Volltext nicht vorhanden.

Gregoritza, Manuel, Messmann, Viktoria, Goepferich, Achim M. und Brandl, Ferdinand P. (2016) Design of hydrogels for delayed antibody release utilizing hydrophobic association and Diels–Alder chemistry in tandem. Journal of Materials Chemistry B 4 (19), S. 3398-3408. Volltext nicht vorhanden.

Sawatzky, Edgar, Wehle, Sarah, Kling, Beata, Wendrich, Jan, Bringmann, Gerhard, Sotriffer, Christoph A., Heilmann, Jörg und Decker, Michael (2016) Discovery of Highly Selective and Nanomolar Carbamate-Based Butyrylcholinesterase Inhibitors by Rational Investigation into Their Inhibition Mode. Journal of Medicinal Chemistry 59 (5), S. 2067-2082. Volltext nicht vorhanden.

Obreque-Balboa, José-Esteban, Sun, Qiu, Bernhardt, Günther, König, Burkhard und Buschauer, Armin (2016) Flavonoid derivatives as selective ABCC1 modulators: Synthesis and functional characterization. European Journal of Medicinal Chemistry 109, S. 124-133. Volltext nicht vorhanden.

Hering, Thea, Mühldorf, Bernd, Wolf, Robert und König, Burkhard (2016) Halogenase-Inspired Oxidative Chlorination Using Flavin
Photocatalysis.
Angewandte Chemie International Edition 55, S. 5342-5345. Volltext nicht vorhanden.

Kariminia, Amina, Holtan, Shernan G., Ivison, Sabine, Rozmus, Jacob, Hebert, Marie-Josée, Martin, Paul J., Lee, Stephanie J., Wolff, Daniel, Subrt, Peter, Abdossamadi, Sayeh, Sung, Susanna, Storek, Jan, Levings, Megan, Aljurf, Mahmoud, Arora, Mukta, Cutler, Corey, Gallagher, Geneviève, Kuruvilla, John, Lipton, Jeff, Nevill, Thomas J., Newell, Laura F., Panzarella, Tony, Pidala, Joseph, Popradi, Gizelle, Szwajcer, David, Tay, Jason , Toze, Cynthia L., Walker, Irwin, Couban, Stephen, Storer, Barry E. und Schultz, Kirk R. (2016) Heterogeneity of chronic graft-versus-host disease biomarkers: association with CXCL10 and CXCR3+ NK cells. Blood 127 (24), S. 3082-3091. Volltext nicht vorhanden.

Dove, Stefan (2016) Mammalian Nucleotidyl Cyclases and Their Nucleotide Binding Sites. In: Seifert, Roland, (ed.) Non-canonical Cyclic Nucleotides. Handbook of Experimental Pharmacology, 238. Springer International Publishing, Cham, Switzerland, S. 49-66. ISBN 978-3-319-52673-7 (online), 978-3-319-52671-3 (print). Volltext nicht vorhanden.

Keller, Max, Kuhn, Kilian K., Einsiedel, Jürgen, Hübner, Harald, Biselli, Sabrina, Mollereau, Catherine , Wifling, David, Svobodova, Jaroslava, Bernhardt, Günther, Cabrele, Chiara , Vanderheyden, Patrick, Gmeiner, Peter und Buschauer, Armin (2016) Mimicking of arginine by functionalized Nω-carbamoylated arginine as a new broadly applicable approach to labeled bioactive peptides: high affinity angiotensin, neuropeptide Y, neuropeptide FF and neurotensin receptor ligands as examples. Journal of Medicinal Chemistry 59 (5), S. 1925-1945. Volltext nicht vorhanden.

Gregoritza, Manuel, Goepferich, Achim und Brandl, Ferdinand (2016) Polyanions effectively prevent protein conjugation and activity loss during hydrogel cross-linking. Journal of Controlled Release 238, S. 92-102. Volltext nicht vorhanden.

Khan, Nadia, Saad, Ali, Nurulain, Syed M., Darras, Fouad H., Decker, Michael und Sadek, Bassem (2016) The dual-acting H3 receptor antagonist and AChE inhibitor UW-MD-71 dose-dependently enhances memory retrieval and reverses dizocilpine-induced memory impairment in rats. Behavioural Brain Research 297, S. 155-164. Volltext nicht vorhanden.

Kratzer, Alexander, Kees, Frieder und Dorn, Christoph (2016) Unbound fraction of fluconazole and linezolid in human plasma as determined by ultrafiltration: Impact of membrane type. Journal of Chromatography B 1039, S. 74-78. Volltext nicht vorhanden.

Huang, Guozheng , Schramm, Simon, Heilmann, Jörg, Biedermann, David, Křen, Vladimír und Decker, Michael (2016) Unconventional application of the Mitsunobu reaction: Selective flavonolignan dehydration yielding hydnocarpins. Beilstein Journal of Organic Chemistry 12, S. 662-669. Volltext nicht vorhanden.

Koehler, Julia, Wallmeyer, Leonie, Hedtrich, Sarah, Goepferich, Achim M. und Brandl, Ferdinand P. (2016) pH-Modulating Poly(ethylene glycol)/Alginate Hydrogel Dressings for the Treatment of Chronic Wounds. Macromolecular Bioscience 17 (5), S. 1600369. Volltext nicht vorhanden.

Kirchhof, Susanne (2015) Diels Alder Hydrogels as Intraocular Drug Delivery Systems for Antibodies. Dissertation, Universität Regensburg.

Wiesneth, Stefan, Petereit, Frank und Jürgenliemk, Guido (2015) Salix daphnoides: A Screening for oligomeric and polymeric flavan-3-ols. In: 7th International Conference on Polyphenols and Health (ICPH), 27.-30. Okt. 2015, Tours, France. Volltext nicht vorhanden.

Meinel, Thomas Raphael (2015) Neuronale alpha-adrenerge Stimulation von IFN-gamma, IL-6 und CXCL1 in murinen Milzen im Tiermodell der Arthritisspätphase. Dissertation, Universität Regensburg.

Nguyen, Tri Hieu (2015) Phytochemical and biological investigation of the bark of Garcinia fusca Pierre. Dissertation, Universität Regensburg.

Helm, Klaus (2015) Synthese und funktionelle In-vitro-Pharmakologie neuer Liganden des 5-HT2A-Rezeptors aus der Klasse der Tryptamine. Dissertation, Universität Regensburg.

Werner, Kristin, Kälble, Solveig, Wolter, Sabine, Schneider, Erich H., Buschauer, Armin, Neumann, Detlef und Seifert, Roland (2015) Flow cytometric analysis with a fluorescent formyl peptide receptor ligand as a new method to study the pharmacological profile of the histamine H2-receptor. Naunyn Schmiedebergs Archives of Pharmacology 388 (10), S. 1039-1052. Volltext nicht vorhanden.

Wolferstetter, Stefanie, Reinders, Jörg, Schwede, Frank, Ruth, Peter, Schinner, Elisabeth und Schlossmann, Jens (2015) Interaction of cCMP with the cGK, cAK and MAPK Kinases in Murine Tissues. PLoS ONE 10 (5), e0126057.

Keller, Max, Schindler, Lisa, Bernhardt, Günther und Buschauer, Armin (2015) Towards labeled argininamide-type NPY Y1 receptor antagonists: Identification of a favorable propionylation site in BIBO3304. Archiv der Pharmazie 348 (6), S. 390-398. Volltext nicht vorhanden.

Rothenhöfer, Martin, Grundmann, Marco, Bernhardt, Günther, Matysik, Frank-Michael und Buschauer, Armin (2015) High performance anion exchange chromatography with pulsed amperometric detection (HPAEC–PAD) for the sensitive determination of hyaluronan oligosaccharides. Journal of Chromatography B 988 (C), S. 106-115. Volltext nicht vorhanden.

Wifling, David (2015) Constitutive activity of the human histamine H4 receptor: Molecular modelling, binding and functional studies on wild-type and mutant H4R orthologs. Dissertation, Universität Regensburg.

Wiesneth, Stefan, Petereit, Frank und Jürgenliemk, Guido (2015) Polymere Proanthocyanidine aus der Rinde von Salix daphnoides (Polymeric proanthocyanidins from the bark of Salix daphnoides). In: 4. Young Researcher Meeting, 13.-14. März 2015, Münster, Germany. Volltext nicht vorhanden.

Mahli, Abdo (2015) Novel in vitro model for combined effects of alcohol and free fatty acids on hepatocellular lipid accumulation and inflammation. Dissertation, Universität Regensburg.

Wifling, David, Bernhardt, Günther, Dove, Stefan und Buschauer, Armin (2015) The extracellular loop 2 (ECL2) of the human histamine H4 receptor substantially contributes to ligand binding and constitutive activity. PLoS One 10 (1), S. 1-14.

Baumeister, Paul, Erdmann, Daniela, Biselli, Sabrina, Kagermeier, Nicole, Elz, Sigurd, Bernhardt, Günther und Buschauer, Armin (2015) 3HUR-DE257: Development of a tritium-labeled squaramide-type selective histamine H2 receptor antagonist. ChemMedChem 10 (1), S. 83-93. Volltext nicht vorhanden.

Dolles, Dominik, Nimczick, Martin, Scheiner, Matthias, Ramler, Jacqueline, Stadtmüller, Patricia, Sawatzky, Edgar, Drakopoulos, Antonios , Sotriffer, Christoph, Wittmann, Hans-Joachim, Strasser, Andrea und Decker, Michael (2015) Aminobenzimidazoles and Structural Isomers as Templates for Dual-Acting Butyrylcholinesterase Inhibitors andhCB2R Ligands To Combat Neurodegenerative Disorders. ChemMedChem 11 (12), S. 1270-1283. Volltext nicht vorhanden.

Orlando, Zoya, Lengers, Isabelle, Melzig, Matthias F., Buschauer, Armin, Hensel, Andreas und Jose, Joachim (2015) Autodisplay of human hyaluronidase Hyal-1 on Escherichia coli and identification of plant-derived enzyme inhibitors. Molecules 20 (9), S. 15449-15468.

Wittmann, Hans-Joachim und Strasser, Andrea (2015) Binding pathway of histamine to the hH4R, observed by unconstrained molecular dynamics. Bioorganic & Medicinal Chemistry Letters 25, S. 1259-1268. Volltext nicht vorhanden.

Schinner, Elisabeth, Wetzl, Veronika und Schlossmann, Jens (2015) Cyclic Nucleotide Signalling in Kidney Fibrosis. International Journal of Molecular Sciences 16, S. 2320-2351.

Kirchhof, Susanne, Gregoritza, Manuel, Messmann, Viktoria, Hammer, Nadine, Göpferich, Achim und Brandl, Ferdinand (2015) Diels-​Alder hydrogels with enhanced stability: First step toward controlled release of bevacizumab. European Journal of Pharmaceutics and Biopharmaceutics 96, S. 217-225. Volltext nicht vorhanden.

Kirchhof, Susanne, Abrami, Michela, Messmann, Viktoria, Hammer, Nadine, Goepferich, Achim, Grassi, Mario und Brandl, Ferdinand (2015) Diels–Alder hydrogels for controlled antibody release: Correlation between mesh size and release rate. Molecular Pharmaceutics 12 (9), S. 3358-3368. Volltext nicht vorhanden.

Lübker, Carolin, Dove, Stefan, Tang, Wei-Jen, Bieber Urbauer, Ramona J., Moskovitz, Jackob, Urbauer, Jeffrey L. und Seifert, Roland (2015) Different Roles of N-Terminal and C-Terminal Domains in Calmodulin for Activation of Bacillus anthracis Edema Factor. Toxins 7 (7), S. 2598-2614.

Kagermeier, Nicole, Werner, Kristin, Keller, Max, Baumeister, Paul, Bernhardt, Günther, Seifert, Roland und Buschauer, Armin (2015) Dimeric carbamoylguanidine-type histamine H2 receptor ligands: A new class of potent and selective agonists. Bioorganic & Medicinal Chemistry 23 (14), S. 3957-3969. Volltext nicht vorhanden.

Arndt, Stephanie, Wacker, Eva, Dorn, Christoph , Koch, Andreas, Saugspier, Michael, Thasler, W. E., Hartmann, Arndt, Bosserhoff, Anja-Katrin und Hellerbrand, Claus (2015) Enhanced expression of BMP6 inhibits hepatic fibrosis in non-alcoholic fatty liver disease. Gut 64 (6), S. 973-981.

Huber, Stefan, Huettner, Johannes Philip, Hacker, Kristina, Bernhardt, Günther, König, Jörg und Buschauer, Armin (2015) Esters of bendamustine are by far more potent cytotoxic agents than the parent compound against human sarcoma and carcinoma cells. PLoS One 10 (7), PLoSe0133743.

Beermann, Silke, Bernhardt, Guenther, Seifert, Roland, Buschauer, Armin und Neumann, Detlef (2015) Histamine H1- and H4-receptor signaling cooperatively regulate MAPK activation. Biochemical Pharmacology 98 (3), S. 432-439. Volltext nicht vorhanden.

Strasser, Andrea und Buschauer, Armin (2015) Histaminrezeptoren. Pharmakon 3 (2), S. 109-116. Volltext nicht vorhanden.

Kirchhof, Susanne, Goepferich, Achim und Brandl, Ferdinand (2015) Hydrogels in ophthalmic applications. European Journal of Pharmaceutics and Biopharmaceutics 95, part B, S. 227-238. Volltext nicht vorhanden.

Radons, Jürgen, Falk, Werner und Dove, Stefan (2015) Identification of critical regions within the TIR domain of IL-1 receptor type I. The international journal of biochemistry & cell biology 68, S. 15-20. Volltext nicht vorhanden.

Keller, Max, Tränkle, Christian, She, Xueke, Pegoli, Andrea, Bernhardt, Günther, Buschauer, Armin und Read, Roger W. (2015) M2 subtype preferring dibenzodiazepinone-type muscarinic receptor ligands: effect of chemical homo-dimerization on orthosteric (and allosteric?) binding. Bioorganic & Medicinal Chemistry 23 (14), S. 3970-3990. Volltext nicht vorhanden.

Lübker, Carolin, Bieber-Urbauer, Ramona J., Moskovitz, Jackob, Dove, Stefan, Weisemann, Jasmin, Fedorova, Maria, Urbauer, Jeffrey L. und Seifert, Roland (2015) Membranous adenylyl cyclase 1 activation is regulated by oxidation of N- and C-terminal methionine residues in calmodulin. Biochemical Pharmacology 93 (2), S. 196-209. Volltext nicht vorhanden.

Strasser, Andrea, Wittmann, Hans-Joachim, Schneider, Erich H. und Seifert, Roland (2015) Modulation of GPCRs by monovalent cations and anions. Naunyn-Schmiedeberg's Archives of Pharmacology 388, S. 363-380. Volltext nicht vorhanden.

Wifling, David, Löffel, Karolin, Nordemann, Uwe, Strasser, Andrea, Bernhardt, Günther, Dove, Stefan, Seifert, Roland und Buschauer, Armin (2015) Molecular determinants for the high constitutive activity of the human histamine H4 receptor: Functional studies on orthologs and mutants. British Journal of Pharmacology 172, S. 785-798. Volltext nicht vorhanden.

Kaczor, Agnieszka, Guixa-Gonzalez, Ramon, Carrio, Pau, Poso, Antti, Dove, Stefan, Pastor, Manuel und Selent, Jana (2015) Multi-Component Protein - Protein Docking Based Protocol with External Scoring for Modeling Dimers of G Protein-Coupled Receptors. Molecular Informatics 34 (4), S. 246-255. Volltext nicht vorhanden.

Hennig, Robert, Ohlmann, Andreas, Staffel, Janina, Pollinger, Klaus, Haunberger, Alexandra, Breunig, Miriam, Schweda, Frank, Tamm, Ernst R. und Goepferich, Achim (2015) Multivalent nanoparticles bind the retinal and choroidal vasculature. Journal of Controlled Release 220 (Part A), S. 265-274. Volltext nicht vorhanden.

Hennig, Robert, Pollinger, Klaus, Tessmar, Joerg und Göpferich, Achim (2015) Multivalent targeting of AT1 receptors with angiotensin II-​functionalized nanoparticles. Journal of Drug Targeting, S. 1-9. Volltext nicht vorhanden.

Keller, Max, Weiss, Stefan, Hutzler, Christoph, Kuhn, Kilian K., Mollereau, Catherine, Dukorn, Stefanie, Schindler, Lisa, Bernhardt, Günther, König, Burkhard und Buschauer, Armin (2015) N(omega)-carbamoylation of the argininamide moiety: an avenue to insurmountable NPY Y1 receptor antagonists and a radiolabeled selective high affinity molecular tool ([3H]UR-MK299) with extended residence time. Journal of Medicinal Chemistry 58 (22), S. 8834-8849. Volltext nicht vorhanden.

Hennig, Robert und Goepferich, Achim (2015) Nanoparticles for the treatment of ocular neovascularizations. European Journal of Pharmaceutics and Biopharmaceutics 95 (Part B), S. 294-306. Volltext nicht vorhanden.

Sun, Qiu, Heilmann, Jörg und König, Burkhard (2015) Natural phenolic metabolites with anti-angiogenic properties – a review from the chemical point of view. Beilstein Journal of Organic Chemistry 11, S. 249-264.

Kirchhof, Susanne, Strasser, Andrea, Wittmann, Hans-Joachim, Messmann, Viktoria, Hammer, Nadine, Goepferich, Achim und Brandl, Ferdinand (2015) New insights into the cross-linking and degradation mechanism of Diels–Alder hydrogels. Journal of Materials Chemistry B 3, S. 449-457.

Hammer, Nadine, Brandl, Ferdinand, Kirchhof, Susanne, Messmann, Viktoria und Goepferich, Achim (2015) Protein compatibility of selected cross-linking reactions for hydrogels. Macromol. Biosci. 15 (3), S. 405-413. Volltext nicht vorhanden.

Huber, Stefan, Antoni, Frauke, Schickaneder, Christian, Schickaneder, Helmut, Bernhardt, Günther und Buschauer, Armin (2015) Stabilities of neutral and basic esters of bendamustine in plasma compared to the parent compound: Kinetic investigations by HPLC. Journal of Pharmaceutical and Biomedical Analysis 104, S. 137-143. Volltext nicht vorhanden.

Reinartz, Michael T., Kälble, Solveig, Littmann, Timo, Ozawa, Takeaki, Dove, Stefan, Kaever, Volkhard, Wainer, Irving W. und Seifert, Roland (2015) Structure-bias relationships for fenoterol stereoisomers in six molecular and cellular assays at the β2-adrenoceptor. Naunyn-Schmiedeberg's archives of pharmacology 388 (1), S. 51-65. Volltext nicht vorhanden.

Untergehrer, Monika, Bücherl, Daniel, Wittmann, Hans-Joachim, Strasser, Andrea, Heilmann, Jörg und Jürgenliemk, Guido (2015) Structure-dependent deconjugation of flavonoid glucuronides by human beta-glucuronidase - in vitro and in silico analyses. Planta Med. 81 (12/13), S. 1182-1189. Volltext nicht vorhanden.

Huber, Stefan, Wege, Anja K., Bernhardt, Günther, Buschauer, Armin und Brockhoff, Gero (2015) Topotecan-induced ABCG2 expression in MCF-7 cells is associated with decreased CD24 and EpCAM expression and a loss of tumorigenicity. Cytometry A 87 (8), S. 707-716. Volltext nicht vorhanden.

Herrnberger, Leonie, Hennig, Robert, Kremer, Werner, Hellerbrand, Claus, Goepferich, Achim, Kalbitzer, Hans Robert und Tamm, Ernst R. (2014) Formation of Fenestrae in Murine Liver Sinusoids Depends on Plasmalemma Vesicle-Associated Protein and Is Required for Lipoprotein Passage. PLoS ONE 9 (12), e115005.

Cuboni, Serena, Devigny, Christian, Hoogeland, Bastiaan, Strasser, Andrea, Pomplun, Sebastian, Hauger, Barbara, Höfner, Georg, Wanner, Klaus, Eder, Matthias, Buschauer, Armin, Holsboer, Florian und Hausch, Felix (2014) Loratadine and analogs: Discovery and preliminary SAR of inhibitors of the amino acid transporter B0AT2. Journal of Medicinal Chemistry 57 (22), S. 9473-9479. Volltext nicht vorhanden.

Dulla, Balakrishna (2014) Synthesis and pharmacological characterization of novel N & O containing heterocyclic compounds as potential therapeutic agents. Dissertation, Universität Regensburg.

Baumeister, Paul (2014) Molecular tools for G-protein coupled receptors:
Synthesis, pharmacological characterization and [3H]-labeling of subtype-selective ligands for histamine H4 and NPY Y2 receptors.
Dissertation, Universität Regensburg.

Hennig, Robert, Pollinger, Klaus, Veser, Anika, Breunig, Miriam und Goepferich, Achim (2014) Nanoparticle multivalency counterbalances the ligand affinity loss upon PEGylation. Journal of Controlled Release 194, S. 20-27. Volltext nicht vorhanden.

Haunschild, Gundula (2014) Nachweis und molekulare Charakterisierung EpCAM-positiver Zellen im Knochenmark von Mammakarzinom-Patientinnen. Dissertation, Universität Regensburg.

Slenczka, Alkwin, Premke, Tobias, Wirths, Eva-Maria, Pentlehner, Dominik, Lehnig, Rudolf, Richers, Ricarda und Vdovin, Alexander (2014) Microsolvation of Molecules in Superfluid Helium Nanodroplets Revealed by Means of Electronic Spectroscopy. Frontiers in Chemistry.

Schramm, Andrea (2014) Analyse renaler Funktionen der cGMP-abhängigen Proteinkinase II. Dissertation, Universität Regensburg.

Wittmann, Hans-Joachim, Seifert, Roland und Strasser, Andrea (2014) Mathematical analysis of the sodium sensitivity of the human histamine H3 receptor. In silico pharmacology 2.

Tauber, Philipp (2014) Untersuchungen zur Pathogenese von primärem Hyperaldosteronismus in neugeborenen Task3-/- Mäusen und adrenokortikalen Zellen mit KCNJ5-Mutation. Dissertation, Universität Regensburg.

Dove, Stefan (2014) Multivariate analysis of hydrophobic descriptors. ADMET & DMPK 2 (1), S. 3-17.

Dove, Stefan, Danker, Kerstin Yvonne, Stasch, Johannes-Peter, Kaever, Volkhard und Seifert, Roland (2014) Structure/Activity Relationships of (M)ANT- and TNP-Nucleotides for Inhibition of Rat Soluble Guanylyl Cyclase alpha(1)beta(1). Molecular Pharmacology 85 (4), S. 598-607. Volltext nicht vorhanden.

Rothenhöfer, Martin (2014) Analytical approaches to the study of hyaluronan and hyaluronidases: Development and application of hyphenated chromatographic and electrophoretic methods. Dissertation, Universität Regensburg.

Bücherl, Daniel (2014) Isolation of kaempferol glycosides from Ginkgo biloba leaves and synthesis, identification and quantification of their major in vivo metabolites. Dissertation, Universität Regensburg.

Darras, Fouad, Pockes, Steffen , Huang, Guozheng, Wehle, Sarah, Strasser, Andrea, Wittmann, Hans-Joachim, Nimczick, Martin, Sotriffer, Christoph und Decker, Michael (2014) Synthesis, biological evaluation, and computational studies of tri- and tetracyclic nitrogen-bridgehead compounds as potent dual-acting AChE inhibitors and hH3 receptor antagonists. ACS Chemical Neuroscience 5 (3), S. 225-242. Volltext nicht vorhanden.

Kremb, Stephan, Helfer, Markus und Kraus, Birgit (2014) Aqueous Extracts of the Marine Brown Alga Lobophora variegata Inhibit HIV-1 Infection at the Level of Virus Entry into Cells. PloS ONE 9, e103895.

Pollinger, Klaus, Hennig, Robert, Bauer, Stefanie, Breunig, Miriam, Tessmar, Joerg, Buschauer, Armin, Witzgall, Ralph und Göpferich, Achim (2014) Biodistribution of quantum dots in the kidney after intravenous injection. Journal of Nanoscience and Nanotechnology 14 (5), S. 3313-3319. Volltext nicht vorhanden.

Pannem, Rajeswara Rao, Dorn, Christoph , Ahlqvist, Kristofer, Bosserhoff, Anja K., Hellerbrand, Claus und Massoumi, Ramin (2014) CYLD controls c-MYC expression through the JNK-dependent signaling pathway in hepatocellular carcinoma. Carcinogenesis 35 (2), S. 461-468.

Hammer, Nadine, Brandl, Ferdinand, Kirchhof, Susanne und Goepferich, Achim (2014) Cleavable carbamate linkers for controlled protein delivery from hydrogels. Journal of Controlled Release 183, S. 67-76. Volltext nicht vorhanden.

Schweizer, Daniel, Serno, Tim und Goepferich, Achim (2014) Controlled release of therapeutic antibody formats. European Journal of Pharmaceutics and Biopharmaceutics 88 (2), S. 291-309. Volltext nicht vorhanden.

Pannem, Rajeswara R., Dorn, Christoph , Hellerbrand, Claus und Massoumi, Ramin (2014) Cylindromatosis gene CYLD regulates hepatocyte growth factor expression in hepatic stellate cells through interaction with histone deacetylase 7. Hepatology 60 (3), S. 1066-1081.

Dorn, Christoph , Engelmann, Julia C., Saugspier, Michael, Koch, Andreas, Hartmann, Arndt, Müller, Martina, Spang, Rainer, Bosserhoff, Anja und Hellerbrand, Claus (2014) Increased expression of c-Jun in nonalcoholic fatty liver disease. Laboratory Investigation 94 (4), S. 394-408. Volltext nicht vorhanden.

Wolter, Sabine, Dove, Stefan, Golombek, Marina, Schwede, Frank und Seifert, Roland (2014) N4-monobutyryl-cCMP activates PKA RIα and PKA RIIα more potently and with higher efficacy than PKG Iα in vitro but not in vivo. Naunyn-Schmiedeberg's archives of pharmacology 387 (12), S. 1163-1175. Volltext nicht vorhanden.

Werner, Kristin, Neumann, Detlef, Buschauer, Armin und Seifert, Roland (2014) No evidence for histamine H4-receptor in human monocytes. Journal of Pharmacology and Experimental Therapeutics 351 (3), S. 519-526. Volltext nicht vorhanden.

Wager, Eva, Wittmann, Hans-Joachim, Elz, Sigurd und Strasser, Andrea (2014) Pharmacological profile of astemizole-derived compounds at the histamine H1 and H4 receptor - H1/H4 receptor selectivity. Naunyn-Schmiedeberg's Archives of Pharmacology 387, S. 235-250. Volltext nicht vorhanden.

Luschmann, Christoph, Tessmar, Joerg, Schoeberl, Simon, Strauss, O., Luschmann, Karl und Goepferich, Achim (2014) Self-​assembling colloidal system for the ocular administration of cyclosporine A. Cornea 33 (1), S. 77-81. Volltext nicht vorhanden.

Wittmann, Hans-Joachim, Seifert, Roland und Strasser, Andrea (2014) Sodium binding to hH3R and hH4R - a molecular modelling study. Journal of Molecular Modeling 20, S. 2394. Volltext nicht vorhanden.

Geyer, Roland, Kaske, Melanie, Baumeister, Paul und Buschauer, Armin (2014) Synthesis and functional characterization of imbutamine analogs as histamine H3 and H4 receptor ligands. Archiv der Pharmazie (Weinheim, Germany) 347 (2), S. 77-88. Volltext nicht vorhanden.

Geyer, Roland, Igel, Patrick, Kaske, Melanie, Elz, Sigurd und Buschauer, Armin (2014) Synthesis, SAR and selectivity of 2-acyl- and 2-cyano-1-hetarylalkyl-guanidines at the four histamine receptor subtypes: a bioisosteric approach. MedChemComm 5 (1), S. 72-81. Volltext nicht vorhanden.

Endlich, Nicole, Simon, Ole, Goepferich, Achim, Wegner, Henny, Moeller, Marcus J., Rumpel, Elisabeth, Kotb, Ahmed und Endlich, Karlhans (2014) Two-Photon Microscopy Reveals Stationary Podocytes in Living Zebrafish Larvae. Journal of the American Society of Nephrology 25 (4), S. 681-686. Volltext nicht vorhanden.

Schickaneder, Helmut, Buschauer, Armin, Bernhardt, Günther, Schickaneder, Christian, Limmert, Michael, Huber, Stefan, Lubbe, Mathias und Hofmeier, Harald (2013) Esters of bendamustine and related compounds, and medical use thereof. Volltext nicht vorhanden.

Brunner, Elisabeth (2013) Einsatz von Everolimus zur Prävention der chronischen Abstoßung nach orthotoper unilateraler Lungentransplantation in der Ratte. Dissertation, Universität Regensburg.

Schmidt, Sebastian (2013) Phytochemische und pharmakologische in vitro Untersuchungen zu Hypericum empetrifolium WILLD. Dissertation, Universität Regensburg.

Loth, Tina, Hennig, Robert, Kascholke, Christian, Hötzel, Rudi und Hacker, Michael (2013) Reactive and stimuli-responsive maleic anhydride containing macromers–multi-functional cross-linkers and building blocks for hydrogel fabrication. Reactive and Functional Polymers 73 (11), S. 1480-1492. Volltext nicht vorhanden.

Sadek, Bassem, Alisch, Rudi, Buschauer, Armin und Elz, Sigurd (2013) Synthesis and dual histamine H1 and H2 receptor antagonist activity of cyanoguanidine derivatives. Molecules 18 (11), S. 14186-14202.

Dove, Stefan und Buschauer, Armin (2013) G-Protein-gekoppelte Rezeptoren: „Sinnesorgane“ der Zellen. Blick in die Wissenschaft 22 (28), S. 3-9. Volltext nicht vorhanden.

Schreeb, Annemarie, Łażewska, Dorota, Dove, Stefan, Buschauer, Armin, Kieć-Kononiwcz, Katarzyna und Stark, Holger (2013) 2. Histamine H4 receptor ligands. In: Stark, Holger, (ed.) Histamine H4 receptor: a novel drug target for immunoregulation and inflammation. Versita, London, S. 21-62. ISBN 9788376560564. Volltext nicht vorhanden.

Stöckl, Sabine (2013) Der Einfluss von Sox9 auf Zellvitalität und Differenzierungspotential von adulten mesenchymalen Stammzellen. Dissertation, Universität Regensburg.

Keller, Max, Kaske, Melanie, Holzammer, Tobias, Bernhardt, Günther und Buschauer, Armin (2013) Dimeric argininamide-type neuropeptide Y receptor antagonists: chiral discrimination between Y1 and Y4 receptors. Bioorganic and Medicinal Chemistry 21 (21), S. 6303-6322. Volltext nicht vorhanden.

Weisser, Roland (2013) Planung einer Studie zur Etablierung des therapeutischen Referenzbereichs der Wirkstoffkonzentration eines Antidementivums. Dissertation, Universität Regensburg.

Berlicki, Lukasz, Kaske, Melanie, Gutierrez-Abad, Raquel, Bernhardt, Günther, Illa, Ona, Ortuño, Rosa, Cabrele, Chiara, Buschauer, Armin und Reiser, Oliver (2013) Replacement of Thr32 and Gln34 in the C-terminal neuropeptide Y fragment 25-36 by cis-cyclobutane- and cis-cyclopentane β-amino acids shifts selectivity toward the Y4 receptor. Journal of Medicinal Chemistry 56 (21), S. 8422-8431. Volltext nicht vorhanden.

Nordemann, Uwe, Wifling, David, Schnell, David, Bernhardt, Günther, Stark, Holger, Seifert, Roland und Buschauer, Armin (2013) Luciferase reporter gene assay on human, murine and rat histamine H4 receptor orthologs: correlations and discrepancies between distal and proximal readouts. PLoS One 8 (9), e73961.

Bauer, Stefanie, Ochoa Puentes, Cristian, Sun, Qiu, Bause, Manuel, Bernhardt, Günther, König, Burkhard und Buschauer, Armin (2013) Quinoline carboxamide-type ABCG2 modulators: Indole and quinoline moieties as anilide replacements. ChemMedChem 8 (11), S. 1773-1778. Volltext nicht vorhanden.

Holzammer, Tobias (2013) Homology modeling, molecular dynamics simulations and site-directed mutagenesis of histamine H2 receptors. Dissertation, Universität Regensburg.

Kirchhof, Susanne, Brandl, Ferdinand, Hammer, Nadine und Göpferich, Achim (2013) Investigation of the Diels–Alder reaction as a cross-linking mechanism for degradable poly(ethylene glycol) based hydrogels. Journal of Materials Chemistry B 1 (37), S. 4855-4864. Volltext nicht vorhanden.

Kaske, Melanie (2013) In search for potent and selective NPY Y4 receptor ligands: acylguanidines, argininamides and peptide analogs. Dissertation, Universität Regensburg.

Brunskole Hummel, Irena, Kälble, Solveig, Burhenne, Heike, Reinartz, Michael T., Schwede, Frank, Buschauer, Armin und Seifert, Roland (2013) Dissociations in the effects of beta2-adrenergic receptor agonists on cAMP formation and superoxide production in human neutrophils: Support for the concept of functional selectivity. PLoS One 8 (5), e64556.

Zölls, Sarah, Gregoritza, Manuel, Tantipolphan, Ruedeeporn, Wiggenhorn, Michael, Winter, Gerhard, Friess, Wolfgang und Hawe, Andrea (2013) How Subvisible Particles Become Invisible - Relevance of the Refractive Index for Protein Particle Analysis. Journal of Pharmaceutical Sciences 102 (5), S. 1434-1446. Volltext nicht vorhanden.

Kees, Martin Georg, Schaeftlein, André, Haeberle, Helene Anna, Kees, Frieder K., Kloft, Charlotte und Heininger, Alexandra (2013) Population pharmacokinetics and pharmacodynamic evaluation of intravenous and enteral moxifloxacin in surgical intensive care unit patients. The Journal of antimicrobial chemotherapy. Volltext nicht vorhanden.

Ochoa-Puentes, Cristian, Bauer, Stefanie, Kühnle, Matthias, Bernhardt, Günther, Buschauer, Armin und König, Burkhard (2013) Benzanilide – Biphenyl Replacement: A Bioisosteric Approach to Quinoline Carboxamide-type ABCG2 Modulators. ACS Medicinal Chemistry Letters 4 (4), S. 393-396. Volltext nicht vorhanden.

Pluym, Nikola, Baumeister, Paul, Keller, Max, Bernhardt, Günther und Buschauer, Armin (2013) [3H]UR-PLN196: A Selective Nonpeptide Radioligand and Insurmountable Antagonist for the Neuropeptide Y Y2 Receptor. ChemMedChem 8 (4), S. 587-593. Volltext nicht vorhanden.

Miller, Tobias (2013) Polymeric micelles for solubilization and targeting of hydrophobic drugs. Dissertation, Universität Regensburg.

Seifert, Roland, Strasser, Andrea, Schneider, Erich H., Neumann, Detlef, Dove, Stefan und Buschauer, Armin (2013) Molecular and cellular analysis of human histamine receptor subtypes. Trends in Pharmacological Sciences 34 (1), S. 33-58. Volltext nicht vorhanden.

Strasser, Andrea, Wittmann, Hans-Joachim, Buschauer, Armin, Schneider, Erich H. und Seifert, Roland (2013) Species-dependent activities of GPCR ligands: Lessons from histamine receptor orthologs. Trends in Pharmacological Sciences 34 (1), S. 13-32. Volltext nicht vorhanden.

Krautbauer, Sabrina, Wanninger, Josef, Eisinger, Kristina, Hader, Yvonne, Beck, Michael, Kopp, Andrea, Schmid, Andreas, Weiss, Thomas S., Dorn, Christoph und Buechler, Christa (2013) Chemerin is highly expressed in hepatocytes and is induced in non-alcoholic steatohepatitis liver. Experimental and Molecular Pathology 95 (2), S. 199-205. Volltext nicht vorhanden.

Luschmann, Christoph, Tessmar, Joerg, Schoeberl, Simon, Framme, Carsten, Luschmann, Karl und Goepferich, Achim (2013) Developing an in situ nanosuspension: A novel approach towards the efficient administration of poorly soluble drugs at the anterior eye. European Journal of Pharmaceutical Sciences 50 (3-4), S. 385-392. Volltext nicht vorhanden.

Miller, Tobias, van Colen, G., Sander, B., Golas, M., Uezguen, Senta, Weigandt, Markus und Goepferich, Achim (2013) Drug Loading of Polymerics Micelles. Pharmaceutical Research 30 (2), S. 484-595. Volltext nicht vorhanden.

Dietrich, P., Moleda, Lukas, Kees, Frieder K., Müller, M., Straub, R. H., Hellerbrand, C. und Wiest, R. (2013) Dysbalance in sympathetic neurotransmitter release and action in cirrhotic rats: impact of exogenous neuropeptide Y. Journal of hepatology 58 (2), S. 254-261. Volltext nicht vorhanden.

Ferstl, Matthias, Drechsler, Markus, Rachel, Reinhard, Rischer, M., Engel, J., Backofen, Michael und Goepferich, Achim (2013) Impact of Polyelectrolyte Structure on the Shape of Nanoassemblies with Cationic Peptides. European Journal of Pharmaceutical Sciences 102, S. 2599-2607. Volltext nicht vorhanden.

Seifert, Roland und Dove, Stefan (2013) Inhibitors of Bacillus anthracis edema factor. Pharmacology & Therapeutics 140 (2), S. 200-212. Volltext nicht vorhanden.

Mueller, M., Blunk, Torsten, Appel, Bernhard, Maschke, Angelika, Goepferich, Achim und Zellner, J. (2013) Insulin is essential for in vitro chondrogenesis of mesenchymal progenitor cells and influences chondrogenesis in a dose-dependent manner. International orthopaedics 37 (1), S. 153-158. Volltext nicht vorhanden.

Wurster, Eva-Christina, Elbakry, Asmaa, Goepferich, Achim und Breunig, Miriam (2013) Layer-by-layer assembled gold nanoparticles for the delivery of nucleic acids. In: Nanotechnology for Nucleic Acid Delivery : Methods and Protocols. Methods in Molecular Biology, 948. Humana Press; Springer, Totowa, NJ, S. 171-182. ISBN 978-1-62703-139-4 (print), 978-1-627-03140-0 (online). Volltext nicht vorhanden.

Pollinger, Klaus, Hennig, Robert, Ohlmann, Andreas, Fuchshofer, R., Wenzel, Rebecca und Breunig, Miriam (2013) Ligand-functionalized nanoparticles target endothelial cells in retinal capillaries after systemic application. Proceedings of the National Academy of Sciences of the United States of America (PNAS) 25, S. 6115-6120. Volltext nicht vorhanden.

Strasser, Andrea und Wittmann, Hans-Joachim (2013) Modelling of GPCRs - A Practical Handbook. Springer. Volltext nicht vorhanden.

Strasser, Andrea und Wittmann, Hans-Joachim (2013) Molecular modelling studies give hint for the existence of a symmetric hb2R-Gabg-homodimer. J Mol Model 19, S. 4443-4457. Volltext nicht vorhanden.

Hozsa, Constantin, Breunig, Miriam und Goepferich, Achim (2013) Monitoring the Degradation of Reduction-Sensitive Gene Carriers with Fluorescence Spectroscopy and Flow Cytometry. Methods in Molecular Biology 991, S. 171-184. Volltext nicht vorhanden.

Luschmann, Christoph, Herrmann, W., Strauss, Olaf, Luschmann, Karl und Goepferich, Achim (2013) Ocular delivery systems for poorly soluble drugs: An in-vivo evaluation. International Journal of Pharmaceutics 455 (1-2), S. 331-337. Volltext nicht vorhanden.

Schweizer, Daniel, Voitier, I., Heier, A., Serno, Tim, Goepferich, Achim und et, al. (2013) Pharmacokinetics, biocompatibility and bioavailability of a controlled release monoclonal antibody formulation. Journal of Controlled Release 172 (3), S. 975-982. Volltext nicht vorhanden.

Miller, Tobias, Breyer, S., van Colen, G., Mier, W., Haberkorn, U., Geissler, S., Voss, S., Weigandt, Markus und Goepferich, Achim (2013) Premature drug release of polymeric micelles and its effects on tumor targeting. International Journal of Pharmaceutics 445 (1-2), S. 117-124. Volltext nicht vorhanden.

Schweizer, Daniel, Schoenhammer, K., Jahn, M. und Goepferich, Achim (2013) Protein-​Polyanion Interactions for the Controlled Release of Monoclonal Antibodies. Biomacromolecules 14 (1), S. 75-83. Volltext nicht vorhanden.

Holzhauser, C., Liebl, Renate, Goepferich, Achim, Wagenknecht, Hans-Achim und Breunig, Miriam (2013) RNA “Traffic Lights”: An Analytical Tool to Monitor siRNA Integrity. ACS chemical biology 8, S. 890-894. Volltext nicht vorhanden.

Nordemann, Uwe (2013) Radioligand binding and reporter gene assays for histamine H3 and H4 receptor species orthologs. Dissertation, Universität Regensburg.

Bodensteiner, Julian, Baumeister, Paul, Geyer, Roland, Buschauer, Armin und Reiser, Oliver (2013) Synthesis and pharmacological characterization of new tetrahydrofuran based compounds as conformationally constrained histamine receptor ligands. Organic & biomolecular chemistry 11 (24), S. 4040-4055.

Göpferich, Achim (2013) To pause a moment. European Journal of Pharmaceutics and Biopharmaceutics 85 (3), S. 328. Volltext nicht vorhanden.

Dorn, Christoph , Massinger, Sabine, Wuzik, Andreas, Heilmann, Jörg und Hellerbrand, Claus (2013) Xanthohumol suppresses inflammatory response to warm ischemia–reperfusion induced liver injury. Experimental and Molecular Pathology 94 (1), S. 10-16. Volltext nicht vorhanden.

Wolfertstetter, Stefanie, Huettner, Johannes Philip und Schlossmann, Jens (2013) cGMP-dependent Protein Kinase Inhibitors in Health and Disease. Pharmaceuticals 6, S. 269-286.

Ertel, Miriam, Bernhardt, Günther, Nink, Jörg und Buschauer, Armin (2012) Novel prodrugs of (1S,9S)-9-[[(1S)-1-carboxy-3-phenylpropyl]amino]octahydro-10-oxo-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid and their use in transdermal therapeutic systems. Volltext nicht vorhanden.

Memminger, Martin, Keller, Max, Lopuch, Miroslaw, Pop, Nathalie, Bernhardt, Günther, von Angerer, Erwin und Buschauer, Armin (2012) The Neuropeptide Y Y1 receptor: a diagnostic marker? Expression in MCF-7 breast cancer cells is down-regulated by antiestrogens in vitro and in xenografts. PLoS ONE 7 (12), e51032.

Löber, Stefan, Hübner, Harald, Buschauer, Armin, Sanna, Fabrizio, Argiolas, Antonio, Melis, Maria Rosaria und Gmeiner, Peter (2012) Novel azulene derivatives for the treatment of erectile dysfunction. Bioorganic & medicinal chemistry letters 22 (23), S. 7151-7154. Volltext nicht vorhanden.

Saugspier, Michael Sebastian (2012) Analysis of the anti-fibrotic effects of hop bitter acids on hepatic stellate cells and their anti-tumorigenic effects on hepatocellular carcinoma cells. Dissertation, Universität Regensburg.

Rothenhöfer, Martin, Scherübl, Rosmarie, Bernhardt, Günther, Heilmann, Jörg und Buschauer, Armin (2012) Qualitative and quantitative analysis of hyaluronan oligosaccharides with high performance thin layer chromatography using reagent-free derivatization on amino-modified silica and electrospray ionization-quadrupole time-of-flight mass spectrometry coupling on normal phase. Journal of chromatography. A 1248, S. 169-77. Volltext nicht vorhanden.

Ertel, Miriam (2012) Ambivalence of drug metabolism: Exploration of cilazapril and candesartan prodrugs for transdermal delivery and search for toxic reactive intermediates of N(G)-acylated hetarylpropylguanidines. Dissertation, Universität Regensburg.

Hild, Wolfgang (2012) Cellular nanoparticle delivery by G-protein coupled receptors. Dissertation, Universität Regensburg.

Reher, Till M., Neumann, Detlef, Buschauer, Armin und Seifert, Roland (2012) Incomplete activation of human eosinophils via the histamine H(4)-receptor: Evidence for ligand-specific receptor conformations. Biochemical Pharmacology 84 (2), S. 192-203. Volltext nicht vorhanden.

Seifert, Roland und Dove, Stefan (2012) 3/14. Molecular analysis of agonist stereoisomers at β2-adrenoceptors. In: Jozwiak, Krzysztof und Lough, W. John und Wainer, Irving W., (eds.) Drug stereochemistry : Analytical methods and pharmacology. 3. ed. Informa Healthcare, New York, S. 274-293. ISBN 9781420092387. Volltext nicht vorhanden.

Deml, Karl-Friedrich (2012) Interaktionen von Histamin H1-Rezeptoragonisten und
–antagonisten mit dem humanen Histamin H4-Rezeptor.
Dissertation, Universität Regensburg.

Birnkammer, Tobias, Spickenreither, Anja, Brunskole, Irena, Lopuch, Miroslaw, Kagermeier, Nicole, Bernhardt, Günther, Dove, Stefan, Seifert, Roland, Elz, Sigurd und Buschauer, Armin (2012) The bivalent ligand approach leads to highly potent and selective acylguanidine-type histamine H2 receptor agonists. Journal of Medicinal Chemistry 55 (3), S. 1147-1160. Volltext nicht vorhanden.

Dorn, Christoph , Heilmann, Jörg und Hellerbrand, Claus (2012) Protective effect of xanthohumol on toxin-induced liver inflammation and fibrosis. International Journal of Clinical and Experimental Pathology 5 (1), S. 29-36.

Bauhuber, Sonja, Liebl, Renate, Tomasetti, Luise, Rachel, Reinhard, Goepferich, Achim und Breunig, Miriam (2012) A library of strictly linear poly(ethylene glycol)-poly(ethylene imine) diblock coploymers to perform structure-function relationship on non-viral gene carriers. Journal of Controlled Release 162, S. 446-455. Volltext nicht vorhanden.

Miller, Tobias, Hiller, Alexandra, Uezguen, Senta, Weigandt, Markus und Goepferich, Achim (2012) Analysis of Immediate Stress Mechanisms upon Injection of Polymeric Micelles and Related Colloidal Drug Carriers. Biomacromolecules 13 (6), S. 1707-1718. Volltext nicht vorhanden.

Miller, Tobias, Rachel, Reinhard, Besheer, Ahmed, Uezguen, Senta, Weigand, Markus und Göpferich, Achim (2012) Comparative Investigations on In Vitro Serum Stability of Polymeric Micelle Formulations. Pharmaceutical Research 29 (2), S. 448-459. Volltext nicht vorhanden.

Posavec, Damir, Zabel, Manfred, Bogner, Udo, Bernhardt, Günther und Knör, Günther (2012) Functionalized derivatives of 1,4-dimethylnaphthalene as precursors for biomedical applications: synthesis, structures, spectroscopy and photochemical activation in the presence of dioxygen. Organic & biomolecular chemistry 10 (35), S. 7062-7069.

Saugspier, Michael, Dorn, Christoph , Thasler, Wolfgang E., Gehrig, Manfred, Heilmann, Jörg und Hellerbrand, Claus (2012) Hop bitter acids exhibit anti-fibrogenic effects on hepatic stellate cells in vitro. Experimental and Molecular Pathology 92 (2), S. 222-228. Volltext nicht vorhanden.

Saugspier, Michael, Dorn, Christoph , Czech, Barbara, Gehrig, Manfred, Heilmann, Jörg und Hellerbrand, Claus (2012) Hop bitter acids inhibit tumorigenicity of hepatocellular carcinoma cells in vitro. Oncology Reports 28 (4), S. 1423-1428. Volltext nicht vorhanden.

Appl, Heidrun, Holzammer, Tobias, Dove, Stefan, Haen, Ekkehard, Strasser, Andrea und Seifert, Roland (2012) Interactions of recombinant human histamine H₁R, H₂R, H₃R, and H₄R receptors with 34 antidepressants and antipsychotics. Naunyn-Schmiedeberg's archives of pharmacology 385 (2), S. 145-170. Volltext nicht vorhanden.

Pollinger, Klaus, Hennig, Robert, Breunig, Miriam, Teßmar, Jörg, Ohlmann, Andreas, Tamm, Ernst R., Witzgall, Ralph und Goepferich, Achim (2012) Kidney Podocytes as Specific Targets for cyclo(RGDfC)-Modified Nanoparticles. Small 8, S. 3368-3375. Volltext nicht vorhanden.

Elbakry, Asmaa Mohamed, Wurster, Eva-Christina, Zaky, Alaa, Liebl, Renate, Schindler, Edith, Bauer-Kreisel, Petra, Blunk, Torsten, Rachel, Reinhard, Goepferich, Achim und Breunig, Miriam (2012) Layer-by-Layer Coated Gold Nanoparticles: Size-Dependent Delivery of DNA into Cells. Small 8 (24), S. 3847-3856. Volltext nicht vorhanden.

Heller, Anne, Fischer, Lorenz H., Wolfbeis, Otto S. und Göpferich, Achim (2012) Long time monitoring of the respiratory activity of isolated mitochondria. Experimental Cell Research 318 (14), S. 1667-1672. Volltext nicht vorhanden.

Kees, Martin G., Steinke, T., Moritz, S., Rupprecht, K., Paulus, E. M., Kees, Frieder K., Bucher, M. und Faerber, L. (2012) Omeprazole impairs the absorption of mycophenolate mofetil but not of enteric-coated mycophenolate sodium in healthy volunteers. Journal of clinical pharmacology 52 (8), S. 1265-1272. Volltext nicht vorhanden.

Justinger, Christoph, Schilling, Martin K., Kees, Martin G., Kauffels, Anne, Hirschmann, Katrin, Kopp, Berit, Kees, Frieder K. und Kollmar, Otto (2012) Penetration of moxifloxacin into liver tissue. International journal of antimicrobial agents 39 (6), S. 505-509. Volltext nicht vorhanden.

Bernat, Viachaslau, Heinrich, Markus, Baumeister, Paul, Buschauer, Armin und Tschammer, Nuska (2012) Synthesis and application of the first radioligand targeting the allosteric binding pocket of chemokine receptor CXCR3. ChemMedChem 7 (8), S. 1481-1489. Volltext nicht vorhanden.

Heller, Anne, Brockhoff, Gero und Goepferich, Achim (2012) Targeting drugs to mitochondria. European Journal of Pharmaceutics and Biopharmaceutics 82, S. 1-18. Volltext nicht vorhanden.

Seifert, Roland und Dove, Stefan (2012) Towards selective inhibitors of adenylyl cyclase toxin from Bordetella pertussis. Trends in microbiology 20 (7), S. 343-351. Volltext nicht vorhanden.

Kaftan, Holger, Goepferich, Achim, Kaftan, Silke und Hosemann, Werner (2012) Two different techniques to facilitate reconstruction of the long incus process with bone cement: a feasibility study in human cadaveric temporal bones. European Archives of Oto-Rhino-Laryngology 269, S. 1431-1435. Volltext nicht vorhanden.

Strasser, Andrea und Wittmann, Hans-Joachim (2012) hb2R-Gas-complex: Prediction versus crystal structure - How valuable are predictions based on molecular modelling studies? Journal of Molecular Modeling : J Mol Model 18, S. 3439-3444. Volltext nicht vorhanden.

Brunskole, Irena (2011) Molecular and cellular analysis of aminergic G protein-coupled receptors: histamine H2, H4 and β2-adrenergic receptors, a scientific paradigm. Dissertation, Universität Regensburg.

Geyer, Roland (2011) Hetarylalkyl(aryl)cyanoguanidines as histamine H4 receptor ligands: Synthesis, chiral separation, pharmacological characterization, structure-activity and -selectivity relationships. Dissertation, Universität Regensburg.

Lopuch, Miroslaw (2011) Investigations on neuropeptide Y and histamine receptors by fluorescence-based and radiochemical methods. Dissertation, Universität Regensburg.

Klein, Matthias S., Dorn, Christoph , Saugspier, Michael Sebastian, Hellerbrand, Claus, Oefner, Peter J. und Gronwald, Wolfram (2011) Discrimination of steatosis and NASH in mice using nuclear magnetic resonance spectroscopy. Metabolomics 7 (2), S. 237-246. Volltext nicht vorhanden.

Erdorf, Miriam und Seifert, Roland (2011) Pharmacological characterization of adenylyl cyclase isoforms in rabbit kidney membranes. Naunyn-Schmiedeberg's Archives of Pharmacology 383 (4), S. 357-372. Volltext nicht vorhanden.

Kellermann, K., Dertinger, N., Blobner, M., Kees, Frieder, Kochs, E. F. und Jungwirt, B. (2011) Perioperative moxifloxacin treatment in rats subjected to deep hypothermic circulatory arrest: reduction in cerebral inflammation but without improvement in cognitive performance. Journal of Thoracic and Cardiovascular Surgery 141 (3), S. 796-802. Volltext nicht vorhanden.

Schinner, Elisabeth, Salb, Katharina und Schlossmann, Jens (2011) Signaling via IRAG is essential for NO/cGMP-dependent inhibition of platelet activitation. Platelets. Volltext nicht vorhanden.

Gäbele, Erwin, Dostert, Karin, Dorn, Christoph , Patsenker, Eleonora, Stickel, Felix und Hellerbrand, Claus (2011) A New Model of Interactive Effects of Alcohol and High-Fat Diet on Hepatic Fibrosis. Alcoholism: Clinical and Experimental Research 35 (7), S. 1361-1367. Volltext nicht vorhanden.

Wanninger, Josef, Neumeier, Markus, Bauer, Sabrina, Weiss, Thomas S., Eisinger, Kristina, Walter, Roland, Dorn, Christoph , Hellerbrand, Claus, Schäffler, Andreas und Buechler, Christa (2011) Adiponectin induces the transforming growth factor decoy receptor BAMBI in human hepatocytes. FEBS Letters 585 (9), S. 1338-1344. Volltext nicht vorhanden.

Osman, Shaaban, Brandl, Ferdinand, Zayed, Gamal, Teßmar, Jörg und Göpferich, Achim (2011) Cyclodextrin based hydrogels: Inclusion complex formation and micellization of adamantane and cholesterol grafted polymers. Polymer 52 (21), S. 4806-4812. Volltext nicht vorhanden.

Kirovski, Georgi, Dorn, Christoph , Huber, Hanna, Moleda, Lukas, Niessen, Catrin, Wobser, Hella, Schacherer, Doris, Buechler, Christa, Wiest, Reiner und Hellerbrand, Claus (2011) Elevated systemic monocyte chemoattractrant protein-1 in hepatic steatosis without significant hepatic inflammation. Experimental and Molecular Pathology 91 (3), S. 780-783. Volltext nicht vorhanden.

Schaedlich, A., Rose, C., Kuntsche, J., Caysa, H., Mueller, T., Goepferich, Achim und Maeder, K. (2011) How Stealthy are PEG-PLA Nanoparticles? An NIR In Vivo Study Combined with Detailed Size Measurements. Pharmaceutical Research 28 (8), S. 1995-2007. Volltext nicht vorhanden.

Wittmann, Hans-Joachim, Seifert, Roland und Strasser, Andrea (2011) Influence of the N-terminus and the E2-loop onto the binding kinetics of the antagonist mepyramine and the partial agonist phenoprodifen to H1R. Biochemical Pharmacology 12, S. 1910-1918. Volltext nicht vorhanden.

Wanninger, Josef, Walter, Roland, Bauer, Sabrina, Eisinger, Kristina, Schäffler, Andreas, Dorn, Christoph , Weiss, Thomas S., Hellerbrand, Claus und Buechler, Christa (2011) MMP-9 activity is increased by adiponectin in primary human hepatocytes but even negatively correlates with serum adiponectin in a rodent model of non-alcoholic steatohepatitis. Experimental and Molecular Pathology 91 (2), S. 603-607. Volltext nicht vorhanden.

Wagner, Eva, Wittmann, Hans-Joachim, Elz, Sigurd und Strasser, Andrea (2011) Mepyramine-JNJ7777120-hybrid compounds show high affinity to hH1R, but low affinity to hH4R. Bioorganic & Medicinal Chemistry Letters 21, S. 6274-9280. Volltext nicht vorhanden.

Wittmann, Hans-Joachim, Elz, Sigurd, Seifert, Roland und Strasser, Andrea (2011) Na-methylated phenylhistamines exhibit affinity to the hH4R - a pharmacological and molecular modelling study. Naunyn Schmiedeberg's Arch Pharmacol 384, S. 287-299. Volltext nicht vorhanden.

Ferstl, Matthias, Strasser, Andrea, Wittmann, Hans-Joachim, Drechsler, Markus, Rischer, M., Engl, J. und Goepferich, Achim (2011) Nanofibres Resulating from Cooperative Electrostatic and Hydrophobic Interactions between Peptides and Polyelectrolytes of Opposite Charge. Langmuir 27, S. 14450-14459. Volltext nicht vorhanden.

Henkel, Janin, Gärtner, Daniela, Dorn, Christoph , Hellerbrand, Claus, Schanze, Nancy, Elz, Sheila R. und Püschel, Gerhard P. (2011) Oncostatin M produced in Kupffer cells in response to PGE2: possible contributor to hepatic insulin resistance and steatosis. Laboratory Investigation 91 (7), S. 1107-1117. Volltext nicht vorhanden.

Kees, Martin G., Weber, Susanne, Kees, Frieder K. und Horbach, Thomas (2011) Pharmacokinetics of moxifloxacin in plasma and tissue of morbidly obese patients. The Journal of antimicrobial chemotherapy 66 (10), S. 2330-2335. Volltext nicht vorhanden.

Patsenker, Eleonora, Schneider, Vreni, Ledermann, Monika, Saegesser, Hans, Dorn, Christoph , Hellerbrand, Claus und Stickel, Felix (2011) Potent antifibrotic activity of mTOR inhibitors sirolimus and everolimus but not of cyclosporine A and tacrolimus in experimental liver fibrosis. Journal of Hepatology 55 (2), S. 388-398. Volltext nicht vorhanden.

Bauer, Sabrina, Wanninger, Josef, Schmidhofer, Sandra, Weigert, Johanna, Neumeier, Markus, Dorn, Christoph , Hellerbrand, Claus, Zimara, Nicole, Schäffler, Andreas, Aslanidis, Charalampos und Buechler, Christa (2011) Sterol Regulatory Element-Binding Protein 2 (SREBP2) Activation after Excess Triglyceride Storage Induces Chemerin in Hypertrophic Adipocytes. Endocrinology 152 (1), S. 26-35. Volltext nicht vorhanden.

Schaedlich, A., Caysa, H., Mueller, T., Tenambergen, F., Rose, Cornelia, Goepferich, Achim, Kuntsche, J. und Maeder, K. (2011) Tumor Accumulation of NIR Fluorescent PEG PLA Nanoparticles: Impact of Particle Size and Human Xenograft Tumor Model. ACS Nano 5, S. 8710-8720. Volltext nicht vorhanden.

Kees, M. G., Hilpert, J. W., Gnewuch, C., Kees, F. und Voegeler, S. (2010) Clearance of vancomycin during continuous infusion in intensive care unit patients: correlation with measured and estimated creatinine clearance and serum cystatin C. International Journal of Antimicrobial Agents 36 (6), S. 545-548. Volltext nicht vorhanden.

Schnell, David, Strasser, Andrea und Seifert, Roland (2010) Comparison of the pharmacological properties of human and rat histamine H(3)-receptors. Biochemical Pharmacology 80 (9), S. 1437-1449. Volltext nicht vorhanden.

Mathar, I., Vennekens, R., Meissner, M., Kees, Frieder K., Van der Mieren, G. und Camacho Londono, J. (2010) Increased catecholamine secretion contributes to hypertension in TRPM4-deficient mice. The Journal of Clinical Investigation 120 (9), S. 3267-3279. Volltext nicht vorhanden.

Desch, Matthias, Schinner, Elisabeth, Kees, Frieder K., Hofmann, F., Seifert, Roland und Schlossmann, Jens (2010) Cyclic cytidine 3´,5´-monophosphate (cCMP) signals via cGMP kinase I. FEBS Letters 584 (18), S. 3979-3984. Volltext nicht vorhanden.

Kirovski, Georgi, Gäbele, Erwin, Dorn, Christoph , Moleda, Lukas, Niessen, Christoph, Weiss, Thomas S., Wobser, Hella, Schacherer, Doris, Buechler, Christa, Wasmuth, Hermann E. und Hellerbrand, Claus (2010) Hepatic steatosis causes induction of the chemokine RANTES in the absence of significant hepatic inflammation. International Journal of Clinical and Experimental Pathology 3 (7), S. 675-680.

Schneider, E. H., Strasser, Andrea, Thurmond, R. L. und Seifert, Roland (2010) Structural requirements for inverse agonism and neutral antagonism of indole-, benzimidazole-, and thienopyrrole-derived histamine H4 receptor ligands. Journal of Pharmacology and Experimental Therapeutics 334 (2), S. 513-521. Volltext nicht vorhanden.

Hild, Wolfgang, Pollinger, Klaus, Caporale, Andrea, Cabrele, Chiara, Keller, Max, Pluym, Nicola, Buschauer, Armin , Rachel, Reinhard , Tessmar, Joerg, Breunig, Miriam und Goepferich, Achim (2010) G protein-coupled receptors function as logic gates for nanoparticle binding and cell uptake. Proceedings of the National Academy of Sciences USA: PNAS 107 (23), S. 10667-10672. Volltext nicht vorhanden.

Desch, Matthias, Sigl, K., Hieke, Bernhard, Salb, Katharina, Kees, F. und Bernhard, D. (2010) IRAG determines nitric oxide- and atrial natriuretic peptide-mediated smooth muscle relaxation. Cardiovascular Research 86 (3), S. 496-505. Volltext nicht vorhanden.

Dorn, Christoph , Riener, Marc-Oliver, Kirovski, Georgi, Saugspier, Michael, Steib, Kathrin, Weiss, Thomas S., Gäbele, Erwin, Kristiansen, Glen, Hartmann, Arndt und Hellerbrand, Claus (2010) Expression of fatty acid synthase in nonalcoholic fatty liver disease. International Journal of Clinical and Experimental Pathology 3 (5), S. 505-514.

Schnell, David und Seifert, Roland (2010) Modulation of Histamine H(3) receptor function by monovalent ions. Neuroscience Letters 472 (2), S. 114-118. Volltext nicht vorhanden.

Schnell, David, Burleigh, Katrina, Seifert, Roland und Trick, Jonathan (2010) No evidence for functional selectivity of proxyfan at the human histamine H3 receptor coupled to defined Gi/Go protein heterotrimers. Journal of Pharmacology and Experimental Therapeutics . JPET 332 (3), S. 996-1005. Volltext nicht vorhanden.

Dietl, Katrin, Renner, Kathrin, Dettmer, Katja, Timischl, Birgit, Eberhart, Karin, Dorn, Christoph , Hellerbrand, Claus, Kastenberger, Michael, Kunz-Schughart, Leoni A., Oefner, Peter J., Andreesen, Reinhard, Gottfried, Eva und Kreutz, Marina (2010) Lactic acid and acidification inhibit TNF secretion and glycolysis of human monocytes. Journal of immunology 184 (3), S. 1200-1209. Volltext nicht vorhanden.

Strasser, Andrea und Wittmann, Hans-Joachim (2010) 3D-QSAR CoMFA study to predict orientation of suprahistaprodifens and phenoprodifens in the binding-pocket of four histamine H1-receptor species. Molecular Informatics 29, S. 333-341. Volltext nicht vorhanden.

Schoenhammer, K., Boisclair, J., Schuetz, H., Petersen, H. und Göpferich, Achim (2010) Biocompatibility of an injectable in situ forming depot for peptide delivery. European Journal of Pharmaceutical Sciences 99 (10), S. 4390-4399. Volltext nicht vorhanden.

Brandl, Ferdinand, Hammer, Nadine, Blunk, Torsten, Teßmar, Jörg und Göpferich, Achim (2010) Biodegradable hydrogels for time-controlled release of tethered peptides or proteins. Biomacromolecules 11 (2), S. 496-504. Volltext nicht vorhanden.

Bauer-Kreisel, Petra, Göpferich, Achim und Blunk, Torsten (2010) Cell-delivery therapeutics for adipose tissue regeneration. Advanced Drug Delivery Reviews 62 (7-8), S. 798-813. Volltext nicht vorhanden.

Strasser, Andrea und Wittmann, Hans-Joachim (2010) Distinct interactions between the human adrenergic b2 receptor and Gas - an in silico study. J Mol Model 16, S. 1307-1318. Volltext nicht vorhanden.

Brandl, Ferdinand, Seitz, Anna Katharina, Teßmar, Jörg, Blunk, Torsten und Göpferich, Achim (2010) Enzymatically degradable poly(ethylene glycol) based hydrogels for adipose tissue engineering. Biomaterials 31 (14), S. 3957-3966. Volltext nicht vorhanden.

Brandl, Ferdinand, Kastner, Fritz, Gschwind, R. M., Blunk, Torsten, Teßmar, Jörg und Göpferich, Achim (2010) Hydrogel-based drug delivery systems: Comparison of drug diffusivity and release kinetics. Journal of Controlled Release 142 (2), S. 221-228. Volltext nicht vorhanden.

Berndl, Sina, Breunig, Miriam, Göpferich, Achim und Wagenknecht, Hans-Achim (2010) Imaging of RNA delivery to cells by thiazole orange as a fluorescent RNA base substitution. Organic & Biomolecular Chemistry 8 (5), S. 997-999. Volltext nicht vorhanden.

Schneider, Erich, Schnell, David, Strasser, Andrea, Dove, Stefan und Seifert, Roland (2010) Impact of the DRY motif and the missing "ionic lock" on constitutive activity and G-protein coupling of the human histamine H4 receptor. J Pharmacol Exp Ther : The journal of pharmacology and experimental therapeutics 333 (2), S. 382-392. Volltext nicht vorhanden.

Strasser, Andrea und Wittmann, Hans-Joachim (2010) In silico analysis of the histaprodifen induced pathway of the guinea-pig histamine H1 receptor. Journal of computer- aided molecular design : J Comput Aided Mol Des 24, S. 759-769. Volltext nicht vorhanden.

Henke, Matthias, Brandl, Ferdinand, Göpferich, Achim und Teßmar, Jörg (2010) Size-dependent release of fluorescent macromolecules and nanoparticles from radically cross-linked hydrogels. European Journal of Pharmaceutics and Biopharmaceutics 74 (2), S. 184-192. Volltext nicht vorhanden.

Holzhauser, C., Berndl, Sina, Menacher, Florian, Breunig, Miriam, Göpferich, Achim und Wagenknecht, Hans-Achim (2010) Synthesis and Optical Properties of Cyanine Dyes as Fluorescent DNA Base Substitutions for Live Cell Imaging. European Journal of Organic Chemistry (7), S. 1239-1248. Volltext nicht vorhanden.

Zaky, A., Elbakry, Asmaa, Ehmer, Axel, Breunig, Miriam und Göpferich, Achim (2010) The mechanism of protein release from triglyceride microspheres. Journal of Controlled Release 147 (2), S. 202-210. Volltext nicht vorhanden.

Dorn, Christoph , Bataille, Frauke, Gaebele, Erwin, Heilmann, Jörg und Hellerbrand, Claus (2010) Xanthohumol feeding does not impair organ function and homoeostasis in mice. Food and Chemical Toxicology 48 (7), S. 1890-1897. Volltext nicht vorhanden.

Dorn, Christoph , Kraus, Birgit, Motyl, Magdalena, Weiss, Thomas S., Gehrig, Manfred, Schoelmerich, Juergen, Heilmann, Jörg und Hellerbrand, Claus (2010) Xanthohumol, a chalcon derived from hops, inhibits hepatic inflammation and fibrosis. Molecular nutrition & food research 54 (Suppl.), S205-S213. Volltext nicht vorhanden.

Dorn, Christoph , Weiss, Thomas S., Heilmann, Jörg und Hellerbrand, Claus (2010) Xanthohumol, a prenylated chalcone derived from hops, inhibits proliferation, migration and interleukin-8 expression of hepatocellular carcinoma cells. International journal of oncology 36 (2), S. 435-441. Volltext nicht vorhanden.

Göpferich, Achim und Rothschenk, Stefan (2009) Cross-linked polymer matrix, in particular for administering protein drugs into the eye. DE102008016998. Volltext nicht vorhanden.

Arndt, Stephanie, Mägdefrau, Ulrike, Dorn, Christoph , Schardt, Katharina, Hellerbrand, Claus und Bosserhoff, Anja–Katrin (2009) Iron-Induced Expression of Bone Morphogenic Protein 6 in Intestinal Cells Is the Main Regulator of Hepatic Hepcidin Expression In Vivo. Gastroenterology 138 (1), S. 372-382. Volltext nicht vorhanden.

Schoenhammer, K., Petersen, H., Guethlein, F. und Göpferich, Achim (2009) Poly(ethylene-glycol) 500 Dimethylether as Novel Solvent for Injectable In Situ Forming Depots. Pharmaceutical Research 26 (12), S. 2568-2577. Volltext nicht vorhanden.

Weiser, Barbara, Sommer, Florian, Neubauer, M., Seitz, Anna Katharina, Teßmar, Jörg, Göpferich, Achim und Blunk, Torsten (2009) Ascorbic Acid Enhances Adipogenesis of Bone Marrow-Derived Mesenchymal Stromal Cells. Cells Tissues Organs 189 (6), S. 373-381. Volltext nicht vorhanden.

Wittmann, Hans-Joachim, Seifert, Roland und Strasser, Andrea (2009) Contribution of binding enthalpy and entropy to affinity of antagonist and agonist binding at human and guinea pig histamine H1-receptor. Molecular Pharmacology 76, S. 25-37. Volltext nicht vorhanden.

Bauhuber, Sonja, Hozsa, Constantin, Breunig, Miriam und Göpferich, Achim (2009) Delivery of Nucleic Acids via Disulfide-Based Carrier Systems. Advanced Materials (Weinheim, Germany) 21 (32-33), S. 3286-3306. Volltext nicht vorhanden.

Beule, A. G., Steinmeier, E., Kaftan, H., Biebler, K.-E., Göpferich, Achim, Wolf, Eva und Hosemann, W. (2009) Effects of a dexamethasone-releasing stent on osteoneogenesis in a rabbit model. American journal of rhinology & allergy 23 (4), S. 433-436. Volltext nicht vorhanden.

Schuessele, Andrea, Mayr, H., Teßmar, Jörg und Göpferich, Achim (2009) Enhanced BMP-2 performance on hydroxyapatite ceramic surfaces. Journal of Biomedical Materials Research Part A 90A (4), S. 959-971. Volltext nicht vorhanden.

Sommer, Florian, Brandl, Ferdinand, Weiser, Barbara, Teßmar, Jörg, Blunk, Torsten und Göpferich, Achim (2009) FACS as useful tool to study distinct hyalocyte populations. Experimental Eye Research 88 (5), S. 995-999. Volltext nicht vorhanden.

Schoenhammer, K., Petersen, H., Guethlein, F. und Göpferich, Achim (2009) Injectable in situ forming depot systems: PEG-DAE as novel solvent for improved PLGA storage stability. International Journal of Pharmaceutics 371 (1-2), S. 33-39. Volltext nicht vorhanden.

Deml, Karl-Friedrich, Beermann, S, Neumann, Detlef, Strasser, Andrea und Seifert, Roland (2009) Interactions of histamine H1-receptor agonists and antagonists with the human histamine H4-receptor. Mol Pharmacol : Molecular pharmacology 76 (5), S. 1019-1030. Volltext nicht vorhanden.

Elbakry, Asmaa, Zaky, A., Liebl, Renate, Rachel, Reinhard, Göpferich, Achim und Breunig, Miriam (2009) Layer-by-Layer Assembled Gold Nanoparticles for siRNA Delivery. Nano Letters 9 (5), S. 2059-2064. Volltext nicht vorhanden.

Wobser, Hella, Dorn, Christoph , Weiss, Thomas S., Amann, Thomas, Bollheimer, Cornelius, Büttner, Roland, Schölmerich, Jürgen und Hellerbrand, Claus (2009) Lipid accumulation in hepatocytes induces fibrogenic activation of hepatic stellate cells. Cell Research 19 (8), S. 996-1005. Volltext nicht vorhanden.

Strasser, Andrea (2009) Molecular Modelling and QSAR-based design of histamine receptor ligands. Expert Opinion on Drug Discovery (4), S. 1061-1075. Volltext nicht vorhanden.

Appel, Bernhard, Baumer, Julia, Eyrich, Daniela, Sarhan, Hatem, Taso, S., Englert, Carsten und Göpferich, Achim (2009) Synergistic effects of growth and differentiation factor-5 (GDF-5) and insulin on expanded chondrocytes in a 3-D environment. Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 17 (11), S. 1503-1512. Volltext nicht vorhanden.

Koelwel, C., Rothschenk, Stefan, Fuchs-Koelwel, B., Gabler, B., Lohmann, C. und Göpferich, Achim (2008) Alginate inserts loaded with epidermal growth factor for the treatment of keratoconjunctivitis sicca. Pharmaceutical Development and Technology 13 (3), S. 221-231. Volltext nicht vorhanden.

Beule, A. G., Scharf, C., Biebler, K.-E., Göpferich, Achim, Steinmeier, E., Wolf, E., Hosemann, W. und Kaftan, H. (2008) Effects of Topically Applied Dexamethasone on Mucosal Wound Healing Using a Drug-Releasing Stent. The Laryngoscope 118 (11), S. 2073-2077. Volltext nicht vorhanden.

Sommer, Florian, Pollinger, Klaus, Brandl, Ferdinand, Weiser, Barbara, Teßmar, Jörg, Blunk, Torsten und Göpferich, Achim (2008) Hyalocyte proliferation and ECM accumulation modulated by bFGF and TGF-β1. Graefe's Archive for Clinical and Experimental Ophthalmology 246 (9), S. 1275-1284. Volltext nicht vorhanden.

Weiser, Barbara, Prantl, Lukas, Schubert, Thomas E. O., Zellner, J., Fischbach-Teschl, Claudia, Spruss, Thilo, Seitz, Anna Katharina, Teßmar, Jörg, Göpferich, Achim und Blunk, Torsten (2008) In Vivo Development and Long-Term Survival of Engineered Adipose Tissue Depend on In Vitro Precultivation Strategy. Tissue Engineering Part A 14 (2), S. 275-284. Volltext nicht vorhanden.

Göpferich, Achim (2008) Interactive polymers for pharmaceutical and biomedical applications. European journal of pharmaceutics and biopharmaceutics 68 (1), S. 1. Volltext nicht vorhanden.

Breunig, Miriam, Hosza, C., Lungwitz, Uta, Watanabe, K., Umeda, I., Kato, H. und Göpferich, Achim (2008) Mechanistic investigation of poly(ethylene imine)-based siRNA delivery: Disulfide bonds boost intracellular release of the cargo. Journal of Controlled Release 130 (1), S. 57-63. Volltext nicht vorhanden.

Lungwitz, Uta, Breunig, Miriam, Liebl, Renate, Blunk, Torsten und Göpferich, Achim (2008) Methoxy poly(ethylene glycol) – Low molecular weight linear polyethylenimine-derived copolymers enable polyplex shielding. European Journal of Pharmaceutics and Biopharmaceutics 69 (1), S. 134-148. Volltext nicht vorhanden.

Gäbele, Erwin, Mühlbauer, Marcus, Dorn, Christoph , Weiss, Thomas S., Froh, Matthias, Schnabl, Bernd, Wiest, Reiner, Schölmerich, Jürgen, Obermeier, Florian und Hellerbrand, Claus (2008) Role of TLR9 in hepatic stellate cells and experimental liver fibrosis. Biochemical and Biophysical Research Communications 376 (2), S. 271-276. Volltext nicht vorhanden.

Preuss, Hendrik, Ghorai, Prasanta, Kraus, Anja, Dove, Stefan, Buschauer, Armin und Seifert, Roland (2007) Point Mutations in the Second Extracellular Loop of the Histamine H2 Receptor do not affect the Species-Selective Activity of Guanidine-Type Agonists. Naunyn Schmiedebergs Arch. Pharmacol. 376 (4), S. 253-264. Zugang zum Volltext eingeschränkt.

Klinker, J. F., Schwaner, I., Offermanns, S., Hagelüken, A. und Seifert, Roland (1994) Differential activation of dibutyryl cAMP-differentiated HL-60 human leukemia cells by chemoattractants. Biochemical pharmacology 48 (10), S. 1857-1864.

Wenzel-Seifert, K., Schächtele, C., Hummel, R., Grünbaum, L. und Seifert, Roland (1994) Evidence that inhibition of phorbol ester-induced superoxide anion formation by cyclosporin A in phagocytes is not mediated by direct inhibition of protein kinase C. Biochemical pharmacology 48 (5), S. 859-864.

Seifert, Roland, Grünbaum, L. und Schultz, Günter (1994) Histamine H1-receptors in HL-60 monocytes are coupled to Gi-proteins and pertussis toxin-insensitive G-proteins and mediate activation of Ca2+ influx without concomitant Ca2+ mobilization from intracellular stores. Naunyn-Schmiedeberg's archives of pharmacology 349 (4), S. 355-361.

Musgrave, I. F. und Seifert, Roland (1994) Human neutrophils and HL-60 cells do not possess alpha 2-adrenoceptors. Biochemical pharmacology 47 (2), S. 233-239.

Hagelüken, A., Grünbaum, L., Nürnberg, B., Harhammer, R., Schunack, W. und Seifert, Roland (1994) Lipophilic beta-adrenoceptor antagonists and local anesthetics are effective direct activators of G-proteins. Biochemical pharmacology 47 (10), S. 1789-1795.

Musgrave, I. F., Seifert, Roland und Schultz, Günter (1994) Maitotoxin activates cation channels distinct from the receptor-activated non-selective cation channels of HL-60 cells. The Biochemical journal 301 ( Pt 2, S. 437-441.

Klinker, J. F., Hagelüken, A., Grünbaum, L., Heilmann, I., Nürnberg, B., Harhammer, R., Offermanns, S., Schwaner, I., Ervens, J., Wenzel-Seifert, K., Müller, T. und Seifert, Roland (1994) Mastoparan may activate GTP hydrolysis by Gi-proteins in HL-60 membranes indirectly through interaction with nucleoside diphosphate kinase. The Biochemical journal 304 ( Pt 2, S. 377-383.

Wenzel-Seifert, K., Schächtele, C. und Seifert, Roland (1994) N-protein kinase C isoenzymes may be involved in the regulation of various neutrophil functions. Biochemical and biophysical research communications 200 (3), S. 1536-1543.

Blunk, Torsten (1994) Plasmaproteinadsorption auf kolloidalen Arzneistoffträgern. Analytik, Korrelation mit Oberflächeneigenschaften, Implikationen für das Drug Targeting. Dissertation, Kiel, Univ..

Naim, M., Seifert, Roland, Nürnberg, B., Grünbaum, L. und Schultz, Günter (1994) Some taste substances are direct activators of G-proteins. The Biochemical journal 297 ( Pt 3, S. 451-454.

Berger, M., Offermanns, S., Seifert, Roland und Schultz, Günter (1994) Synthetic lipopeptide Pam3CysSer(Lys)4 is an effective activator of human platelets. The American journal of physiology 266 (6 Pt 1), C1684-C1691.

Seifert, Roland, Hagelüken, A., Höer, A., Höer, D., Grünbaum, L., Offermanns, S., Schwaner, I., Zingel, V., Schunack, W. und Schultz, Günter (1994) The H1 receptor agonist 2-(3-chlorophenyl)histamine activates Gi proteins in HL-60 cells through a mechanism that is independent of known histamine receptor subtypes. Molecular Pharmacology 45 (4), S. 578-586.

Tsang, K. W., Roberts, P., Read, R. C., Kees, Frieder, Wilson, R. und Cole, P. J. (1994) The concentrations of clarithromycin and its 14-hydroxy metabolite in sputum of patients with bronchiectasis following single dose oral administration. The Journal of antimicrobial chemotherapy 33 (2), S. 289-297.

Honeybourne, D., Kees, Frieder K., Andrews, J. M., Baldwin, D. und Wise, R. (1994) The levels of clarithromycin and its 14-hydroxy metabolite in the lung. The European respiratory journal 7 (7), S. 1275-1280.

Blunk, Torsten, Mak, E. und Müller, R. H. (1993) Characterization of Colloidal Drug Carriers. Die pharmazeutische Industrie : pharmind 55 (6), S. 612-615.

Sedlmayr, T., Petersen, F., Raasch, W. und Kees, Frieder K. (1993) Clarithromycin, ein neues Makrolid-Antibiotikum. Wirksamkeit bei puerperalen Infektionen und Übertritt in die Muttermilch [Clarithromycin, a new macrolide antibiotic. Effectiveness in puerperal infections and pharmacokinetics in breast milk]. Geburtshilfe und Frauenheilkunde 53 (7), S. 488-491.

Blunk, Torsten, Hochstrasser, D. F., Sanchez, J. C., Müller, B. W. und Müller, R. H. (1993) Colloidal carriers for intravenous drug targeting: plasma protein adsorption patterns on surface-modified latex particles evaluated by two-dimensional polyacrylamide gel electrophoresis. Electrophoresis 14 (12), S. 1382-1387.

Wenzel-Seifert, Katharina und Seifert, Roland (1993) Cyclosporin H is a potent and selective formyl peptide receptor antagonist. Comparison with N-t-butoxycarbonyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L- leucyl-L-phenylalanine and cyclosporins A, B, C, D, and E. The Journal of Immunology 150 (10), S. 4591-4599.

Bernhardt, Günther (1993) Entwicklung und Anwendung moderner Testverfahren zur Auffindung und Optimierung der Antitumorwirkung neuartiger Diphenylethylendiaminplatin(II)-Komplexe. Habilitation, Regensburg, Universität.

Klinker, J. F., Höer, A., Schwaner, I., Offermanns, S., Wenzel-Seifert, Katharina und Seifert, Roland (1993) Lipopeptides activate Gi-proteins in dibutyryl cyclic AMP-differentiated HL-60 cells. The Biochemical journaL 296 ( Pt 1, S. 245-251.

Wenzel-Seifert, Katharina und Seifert, Roland (1993) Partial inhibition of human neutrophil activation by FK-506 at supratherapeutic concentrations. Naunyn-Schmiedeberg's archives of pharmacology 348 (1), S. 7-13.

Grobecker, H. F. und Kees, Frieder K. (1993) Pharmacokinetic parameters and haemodynamic actions of midodrine in young volunteers. International angiology : a journal of the International Union of Angiology 12 (2), S. 119-124.

Musgrave, I. F., Genieser, H. G., Maronde, E. und Seifert, Roland (1993) Preparations of Rp-cyclic adenosine 3',5'-phosphorothioate (Rp-cAMPS) can contain biologically active amounts of adenosine. FEBS letters 318 (3), S. 227-230.

Rudt, S., Blunk, Torsten und Müller, R. H. (1992) Quantification of Cell Subpopulations, Fractions of Dead
Cells and Debris in Cell Suspensions by Laser Diffractometry.
Die pharmazeutische Industrie 54 (11), S. 966-969.

Müller, R. H., Lherm, C., Herbort, J., Blunk, Torsten und Couvreur, P. (1992) Alkylcyanoacrylate drug carriers: I. Physicochemical characterization of nanoparticles with different alkyl chain length. International Journal of Pharmaceutics 84 (1), S. 1-11.

Dominiak, P., Kees, Frieder K., Welzel, D. und Grobecker, H. (1992) Cardiovascular parameters and catecholamines in volunteers during passive orthostasis. Influence of antihypotensive drugs. Arzneimittel-Forschung 42 (5), S. 637-642.

Krautwurst, D., Seifert, Roland, Hescheler, J. und Schultz, Günter (1992) Formyl peptides and ATP stimulate Ca2+ and Na+ inward currents through non-selective cation channels via G-proteins in dibutyryl cyclic AMP-differentiated HL-60 cells. Involvement of Ca2+ and Na+ in the activation of beta-glucuronidase release and superoxide production. The Biochemical journal 288 ( Pt 3, S. 1025-1035.

Klinz, F. J., Seifert, Roland, Schwaner, I., Gausepohl, H., Frank, R. und Schultz, Günter (1992) Generation of specific antibodies against the rap1A, rap1B and rap2 small GTP-binding proteins. Analysis of rap and ras proteins in membranes from mammalian cells. European journal of biochemistry 207 (1), S. 207-213.

Seifert, Roland, Höer, Ariane, Offermann, Stefan, Buschauer, Armin und Schunack, Walter (1992) Histamine increases Ca^2+ in dibutyryl cyclic AMP-differentiated HL-60 cells via H_1-receptors and is an incomplete secretagogue. Mol. Pharmacol. 42, S. 227-234.

Seifert, Roland, Höer, Ariane, Schwaner, Ingo und Buschauer, Armin (1992) Histamine increases cytosolic Ca^2+ in HL-60 promyelocytes predominantly via H_2-receptors with an unique agonist/antagonist profile and induces functional differentiation. Molecular Pharmacology 42, S. 235-241.

Seifert, Roland, Serke, S., Huhn, D., Bessler, W. G., Hauschildt, S., Metzger, J., Wismüller, K. H. und Jung, G. (1992) Incomplete functional differentiation of HL-60 leukemic cells by synthetic lipopeptides. Partial inhibition by pertussis toxin of enhanced superoxide formation. European journal of biochemistry / FEBS 203 (1-2), S. 143-151.

Offermanns, S., Seifert, Roland, Metzger, J. W., Jung, G., Lieberknecht, A., Schmidt, U. und Schultz, Günter (1992) Lipopeptides are effective stimulators of tyrosine phosphorylation in human myeloid cells. Biochemical Journal 282 ( Pt 2, S. 551-7.

Ervens, J. und Seifert, Roland (1992) Molsidomine inhibits the chemoattractant-induced respiratory burst in human neutrophils via a no-independent mechanism. Biochemical pharmacology 44 (4), S. 637-644.

Kees, Frieder K. (1992) Orale Cephalosporine [Oral cephalosporins]. Medizinische Monatsschrift für Pharmazeuten 15 (1), S. 2-10.

Schwaner, I., Seifert, Roland und Schultz, Günter (1992) Receptor-mediated increases in cytosolic Ca2+ in the human erythroleukaemia cell line involve pertussis toxin-sensitive and -insensitive pathways. The Biochemical journal 281 ( Pt 2, S. 301-307.

Kees, Frieder K., Raasch, W. und Grobecker, H. F. (1992) Strukturelle Charakterisierung eines unbekannten Metaboliten von Ciprofloxacin [Structural characterization of an unknown metabolite of ciprofloxacin]. Arzneimittel-Forschung 42 (4), S. 570-575.

Schwaner, I., Seifert, Roland und Schultz, Günter (1992) The prostacyclin analogues, cicaprost and iloprost, increase cytosolic Ca2+ concentration in the human erythroleukemia cell line, HEL, via pertussis toxin-insensitive G-proteins. Eicosanoids 5 Suppl, S10-512. Volltext nicht vorhanden.

Kees, Frieder K., Lukassek, U., Naber, K. G. und Grobecker, H. (1991) Comparative investigations on the bioavailability of cefuroxime axetil. Arzneimittel-Forschung 41 (8), S. 843-846.

Bernhardt, Günther, Spruss, Thilo und Schönenberger, Helmut (1991) Einsatz menschlicher Tumorzellkulturen als Testmodelle bei der Entwicklung von Wirkstoffen für die Krebstherapie. Forum für interdisziplinäre Forschung : FIF 4, S. 24-28.

Seifert, Roland und Schultz, Günter (1991) The superoxide- forming NADPH oxidase of phagocytes: an enzyme system regulated by multiple mechanisms. Reviews of physiology, biochemistry, and pharmacology, 117. Springer, Berlin. ISBN 3-540-53663-9, 0-387-53663-9.

Seifert, Roland, Schultz, Günter, Richter-Freund, M., Metzger, J., Wiesmüller, K. H., Jung, G., Bessler, W. G. und Hauschildt, S. (1990) Activation of superoxide formation and lysozyme release in human neutrophils by the synthetic lipopeptide Pam3Cys-Ser-(Lys)4. Involvement of guanine-nucleotide-binding proteins and synergism with chemotactic peptides. The Biochemical journal 267 (3), S. 795-802.

Jungblut, P. R. und Seifert, Roland (1990) Analysis by high-resolution two-dimensional electrophoresis of differentiation-dependent alterations in cytosolic protein pattern of HL-60 leukemic cells. Journal of biochemical and biophysical methods 21 (1), S. 47-58.

Burde, Rahel, Buschauer, Armin und Seifert, Roland (1990) Characterization of histamine H_2-receptors in human neutrophils with a series of guanidine analogues of impromidine: Are cell type-specific H_2-receptors involved in the regulation of NADPH oxidase? Naunyn-Schmiedeberg's Archives of Pharmacology 341, S. 455-461.

Kees, Frieder K., Raasch, W., Steger, M. und Grobecker, H. (1990) High-performance liquid chromatographic assay for cefotiam and d3-cefotiam in human serum. Journal of Chromatography B 525 (2), S. 484-489.

Wenzel-Seifert, Katharina und Seifert, Roland (1990) Nucleotide-, chemotactic peptide- and phorbol ester-induced exocytosis in HL-60 leukemic cells. Immunobiology 181 (4-5), S. 298-316.

Kees, Frieder K. und Naber, K. G. (1990) Pharmakokinetik von Cefixim bei Probanden und ein Literaturvergleich mit neuen Ester Prodrug Cephalosporinen [Pharmacokinetics of cefixime in volunteers and a literature comparison with the new ester prodrug cephalosporins]. Infection 18 Suppl 3, S150-S154.

Kees, Frieder K., Naber, K. G., Sigl, G., Ungethüm, W. und Grobecker, H. F. (1990) Relative bioavailability of three cefixime formulations. Arzneimittel-Forschung 40 (3), S. 293-297.

Korting, H. C., Schäfer-Korting, M., Kees, Frieder K., Lukacs, A. und Grobecker, H. (1990) Skin tissue fluid levels of cefotiam in healthy man following oral cefotiam hexetil. European journal of clinical pharmacology 39 (1), S. 33-36.

Kees, Frieder K., Dehner, R., Dittrich, W., Raasch, W. und Grobecker, H. F. (1990) Untersuchungen zur Bioverfügbarkeit von Doxycy [The bioavailability of doxycycline]. Arzneimittel-Forschung 40 (9), S. 1039-1043.

Seifert, Roland, Burde, R. und Schultz, Günter (1989) Activation of NADPH oxidase by purine and pyrimidine nucleotides involves G proteins and is potentiated by chemotactic peptides. The Biochemical journal 259 (3), S. 813-819.

Engel, K. J., Schmidt, W., Sonntag, H. G. und Kees, Frieder K. (1989) Comparative clinical and pharmacokinetic aspects of cefotetan versus cefoxitin plus metronidazole in vaginal hysterectomy. Journal of chemotherapy 1 (4 Supl), S. 1053-1056. Volltext nicht vorhanden.

Seifert, Roland, Jungblut, P. und Schultz, Günter (1989) Differential expression of cytosolic activation factors for NADPH oxidase in HL-60 leukemic cells. Biochemical and biophysical research communications 161 (3), S. 1109-1117.

Naber, K. G., Sörgel, F., Kees, Frieder K., Schumacher, H., Sigl, G., Zürcher, J. und Berger, S. (1989) Enoxacin-Konzentrationen in der Samenflüssigkeit, im Prostatasekret und im Prostataadenomgewebe nach oraler Gabe oder intravenöser Infusion [Enoxacin concentration in seminal fluid, in prostate secretions and in prostatic adenoma tissue following oral administration or intravenous infusion]. Infection 17 Suppl 1, S30-S66.

Schmidt, H. H., Seifert, Roland und Böhme, E. (1989) Formation and release of nitric oxide from human neutrophils and HL-60 cells induced by a chemotactic peptide, platelet activating factor and leukotriene B4. FEBS letters 244 (2), S. 357-360.

Rudolph, U., Koesling, D., Hinsch, K. D., Seifert, Roland, Bigalke, M., Schultz, Günter und Rosenthal, W. (1989) G-protein alpha-subunits in cytosolic and membranous fractions of human neutrophils. Molecular and cellular endocrinology 63 (1-2), S. 143-153.

Burde, Rahel, Seifert, Roland, Buschauer, Armin und Schultz, Günther (1989) Histamine inhibits activation of human neutrophils and HL-60 leukemic cells via H_2-receptors. Naunyn-Schmiedeberg's archives of pharmacology 340, S. 671-678.

Seifert, Roland und Schultz, Günter (1989) Involvement of pyrimidinoceptors in the regulation of cell functions by uridine and by uracil nucleotides. Trends in pharmacological sciences 10 (9), S. 365-369.

Seifert, Roland, Burde, R. und Schultz, Günter (1989) Lack of effect of opioid peptides, morphine and naloxone on superoxide formation in human neutrophils and HL-60 leukemic cells. Naunyn-Schmiedeberg's archives of pharmacology 340 (1), S. 101-106.

Kees, Frieder K., Naber, K. G., Meyer, G. P. und Grobecker, H. (1989) Pharmacokinetics of ciprofloxacin in elderly patients. Arzneimittel-Forschung 39 (4), S. 523-527.

Naber, K. G., Sörgel, F., Kees, Frieder K., Jaehde, U. und Schumacher, H. (1989) Pharmacokinetics of ciprofloxacin in young (healthy volunteers) and elderly patients, and concentrations in prostatic fluid, seminal fluid, and prostatic adenoma tissue following intravenous administration. The American journal of medicine 87 (5supl1), S57-S59.

Seifert, Roland, Wenzel, Katharina, Eckstein, F. und Schultz, Günter (1989) Purine and pyrimidine nucleotides potentiate activation of NADPH oxidase and degranulation by chemotactic peptides and induce aggregation of human neutrophils via G proteins. European journal of biochemistry / FEBS 181 (1), S. 277-285.

Kujath, P., Düsel, W., Bruch, H. P. und Kees, Frieder K. (1989) The pharmacokinetic properties of cefotetan and its relevance for prophylaxis in elective colorectal surgery. Journal of chemotherapy 1 (4 Supl), S. 1002-1004. Volltext nicht vorhanden.

Seifert, Roland, Schächtele, C., Rosenthal, W. und Schultz, Günter (1988) Activation of protein kinase C by cis- and trans-fatty acids and its potentiation by diacylglycerol. Biochemical and biophysical research communications 154 (1), S. 20-26.

Engel, K. J., Schmidt, W., Sonntag, H. G. und Kees, Frieder K. (1988) Comparative clinical and pharmacokinetic aspects of cefotetan versus cefoxitin plus metronidazole in vaginal hysterectomy. Chemioterapia 7 (4), S. 256-260. Volltext nicht vorhanden.

Naber, K. G., Sörgel, F., Kees, Frieder K., Schumacher, H., Metz, R. und Grobecker, H. (1988) In-vitro activity of fleroxacin against isolates causing complicated urinary tract infections and concentrations in seminal and prostatic fluid and in prostatic adenoma tissue. The Journal of antimicrobial chemotherapy 22 Suppl D, S. 199-207.

Kees, Frieder K., Naber, K. G., Schumacher, H. und Grobecker, H. (1988) Penetration of fleroxacin into prostatic secretion and prostatic adenoma tissue. Chemotherapy 34 (6), S. 437-443. Volltext nicht vorhanden.

Schächtele, C., Seifert, Roland und Osswald, H. (1988) Stimulus-dependent inhibition of platelet aggregation by the protein kinase C inhibitors polymyxin B, H-7 and staurosporine. Biochemical and biophysical research communications 151 (1), S. 542-547.

Seifert, Roland und Schächtele, C. (1988) Studies with protein kinase C inhibitors presently available cannot elucidate the role of protein kinase C in the activation of NADPH oxidase. Biochemical and biophysical research communications 152 (2), S. 585-592.

Kujath, P., Düsel, W., Bruch, H. P. und Kees, Frieder K. (1988) The pharmacokinetic properties of cefotetan and its relevance for prophylaxis in elective colorectal surgery. Chemioterapia 7 (4), S. 229-232. Volltext nicht vorhanden.

Seifert, Roland, Rosenthal, W., Schultz, Günter, Wieland, T., Gierschick, P. und Jakobs, K. H. (1988) The role of nucleoside-diphosphate kinase reactions in G protein activation of NADPH oxidase by guanine and adenine nucleotides. European journal of biochemistry / FEBS 175 (1), S. 51-55.

Seifert, Roland, Schächtele, C. und Schultz, Günter (1987) Activation of protein kinase C by cis- and trans-octadecadienoic acids in intact human platelets and its potentiation by diacylglycerol. Biochemical and biophysical research communications 149 (2), S. 762-768.

Naber, K., Kees, Frieder K., Denk, K., Bauernfeind, A. und Grobecker, H. (1987) Carumonam versus ceftazidime: in vitro activity, pharmacokinetics in elderly patients, safety and therapeutic efficacy in the treatment of complicated urinary tract infections. Chemioterapia 6 (2 Supl), S. 517-518. Volltext nicht vorhanden.

Seifert, Roland und Schultz, Günter (1987) Fatty-acid-induced activation of NADPH oxidase in plasma membranes of human neutrophils depends on neutrophil cytosol and is potentiated by stable guanine nucleotides. European journal of biochemistry / FEBS 162 (3), S. 563-569.

Naber, K. G., Adam, D. und Kees, Frieder K. (1987) In vitro activity and concentrations in serum, urine, prostatic secretion and adenoma tissue of ofloxacin in urological patients. Drugs 34 Suppl 1, S44-S50. Volltext nicht vorhanden.

Seifert, Roland und Schultz, Günter (1987) Reversible activation of NADPH oxidase in membranes of HL-60 human leukemic cells. Biochemical and biophysical research communications 146 (3), S. 1296-1302.

Kees, Frieder K., Dominiak, P. und Grobecker, H. (1987) Untersuchungen zur Bioverfügbarkeit von Heptaminol bei Probanden [Bioavailability of heptaminol in healthy subjects]. Arzneimittel-Forschung 37 (10), S. 1182-1185.

Grobecker, H., Kees, Frieder K., Linden, M., Schrader, E. und Welte, S. (1987) Untersuchungen zur Bioverfügbarkeit von Midodrin und 2,5- Dimethoxyphenyl-ß-aminoethanol-hydrochlorid [The bioavailability of midodrin and alpha-2,5-dimethoxyphenyl-beta-aminoethanol hydrochloride]. Arzneimittel-Forschung 37 (4), S. 447-450.

Dominiak, P., Kees, Frieder K. und Grobecker, H. (1986) Circulating and tissue catecholamines in rats with chronic neurogenic hypertension. Basic research in cardiology 81 (1), S. 20-28.

Seifert, Roland, Rosenthal, W. und Schultz, Günter (1986) Guanine nucleotides stimulate NADPH oxidase in membranes of human neutrophils. FEBS letters 205 (1), S. 161-165.

Bernhardt, Günther (1986) Hochdruckuntersuchungen an thermophilen Bakterien. Dissertation, Regensburg, Universität.

Martinez, C., Dominiak, P., Kees, Frieder K. und Grobecker, H. (1986) Inhibition of monoamine oxidase by viloxazine in rats. Arzneimittel-Forschung 36 (5), S. 800-803.

Seifert, Roland (1986) Nikotinamidmethylierung in normalen Geweben und Tumorzellen von Ratte und Maus. Dissertation, Berlin, Freie Universität.

Naber, K. G., Dette, G. A., Kees, Frieder K., Knothe, H. und Grobecker, H. (1986) Pharmacokinetics, in-vitro activity, therapeutic efficacy and clinical safety of aztreonam vs. cefotaxime in the treatment of complicated urinary tract infections. The Journal of antimicrobial chemotherapy 17 (4), S. 517-527.

Grobecker, H., Gessler, I., Delius, W., Dominiak, P. und Kees, Frieder K. (1985) Effect of ketanserin on hemodynamics, plasma-catecholamine concentrations, and serotonin uptake by platelets in volunteers and patients with congestive heart failure. Journal of cardiovascular pharmacology 7, Suppl 7, S102-S104.

Kees, Frieder K., Naber, K. G., Bartoschik-Wich, B., Stockmann, P., Meyer, G. P. und Grobecker, H. (1985) High-performance liquid chromatography analysis of mezlocillin, piperacillin, their degradation products, and of ioxitalamic acid in plasma and urine of healthy volunteers. Arzneimittel-Forschung 35 (7), S. 1099-1104.

Dominiak, P., Kees, Frieder K. und Grobecker, H. (1985) Sympathoadrenal dysfunction in rats with chronic neurogenic hypertension. European journal of pharmacology 107 (2), S. 263-266.

Dominiak, P., Kees, Frieder K. und Grobecker, H. (1984) Changes in peripheral and central catecholaminergic and serotoninergic neurons of rats after acute and subacute administration of nicotine. Klinische Wochenschrift. Supplementum 62 Suppl 2, S. 76-80. Volltext nicht vorhanden.

Kees, Frieder K., Grobecker, H. und Naber, K. G. (1984) High-performance liquid chromatographic analysis of cefotetan epimers in human plasma and urine. Journal of Chromatography B 305 (2), S. 363-371.

Schleicher, E. D., Kees, Frieder K. und Wieland, O. H. (1983) Analysis of total urinary catecholamines by liquid chromatography: methodology, routine experience and clinical interpretations of results. Clinica chimica acta 129 (3), S. 295-302.

Kees, Frieder K., Strehl, E., Dominiak, P., Grobecker, H., Seeger, K., Seidel, G., Neuhaus, B. und Safrany, L. (1983) Cefotaxime and desacetyl cefotaxime in human bile. Infection 11 (2), S. 118-120.

Naber, K. G., Kees, Frieder K. und Grobecker, H. (1983) Ceftazidime: pharmacokinetics in young volunteers versus elderly patients and therapeutic efficacy with complicated urinary tract infections. The Journal of antimicrobial chemotherapy 12 Suppl A, S. 41-45.

Kees, Frieder K., Strehl, E., Seeger, K., Seidel, G., Dominiak, P. und Grobecker, H. (1981) Comparative determination of cefotaxime and desacetyl cefotaxime in serum and bile by bioassay and high-performance liquid chromatography. Arzneimittel-Forschung 31 (2), S. 362-365.

Kees, Frieder K. (1976) Thiaziridindioxide, Thiadiaziridindioxide und ein Beitrag zur Staudinger-Pfenninger-Reaktion. Dissertation, Univ. Würzburg. Volltext nicht vorhanden.

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