Number of items at this level: 579.
Greppmair, Sebastian,
Brinkmann, Alexander,
Roehr, Anka,
Frey, Otto,
Hagel, Stefan,
Dorn, Christoph 
,
Marsot, Amélie,
El-Haffaf, Ibrahim,
Zoller, Michael,
Saller, Thomas,
Zander, Johannes,
Schatz, Lea Marie,
Scharf, Christina,
Briegel, Josef,
Minichmayr, Iris K.,
Wicha, Sebastian G. and
Liebchen, Uwe
(2023)
Towards model-informed precision dosing of piperacillin: multicenter systematic external evaluation of pharmacokinetic models in critically ill adults with a focus on Bayesian forecasting.
Intensive Care Medicine.
Chen, Zhendong,
Taubert, Max,
Chen, Chunli,
Dokos, Charalambos,
Fuhr, Uwe,
Weig, Thomas,
Zoller, Michael,
Heck, Suzette,
Dimitriadis, Konstantinos,
Terpolilli, Nicole,
Kinast, Christina,
Scharf, Christina,
Lier, Constantin,
Dorn, Christoph 
and
Liebchen, Uwe
(2023)
Plasma and Cerebrospinal Fluid Population Pharmacokinetics of Vancomycin in Patients with External Ventricular Drain.
Antimicrobial Agents and Chemotherapy.
Fulltext not available.
Wirth, Ulrike,
Erl, Julia,
Azzam, Saphia,
Hoering, Carina,
Skiba, Michael,
Singh, Ritu,
Hochmuth, Kathrin,
Keller, Max 
,
Wegener, Joachim 
and
König, Burkhard 
(2023)
Monitoring the Reversibility of GPCR Signaling by Combining Photochromic Ligands with Label-free Impedance Analysis.
Angewandte Chemie International Edition, e202215547.
Sanz-Codina, Maria,
Wicha, Sebastian G,
Wulkersdorfer, Beatrix,
Al Jalali, Valentin,
Van Os, Wisse,
Vossen, Matthias G,
Bauer, Martin,
Lackner, Edith,
Dorn, Christoph 
and
Zeitlinger, Markus
(2022)
Comparison of ultrafiltration and microdialysis for ceftriaxone protein-binding determination.
Journal of Antimicrobial Chemotherapy.
Fulltext not available.
Jorda, Anselm 
,
Wulkersdorfer, Beatrix,
Schoergenhofer, Christian,
Matzneller, Peter,
Jalali, Valentin A. L.,
Bauer, Martin,
Wölfl‐Duchek, Michael,
Lackner, Edith,
Dorn, Christoph 
,
Jilma, Bernd and
Zeitlinger, Markus 
(2022)
Effect of the human endotoxin challenge on tedizolid tissue penetration.
British Journal of Clinical Pharmacology, (accept.art.).
Fulltext not available.
Bohley, Marilena,
Dillinger, Andrea E.,
Schweda, Frank,
Ohlmann, Andreas,
Braunger, Barbara M.,
Tamm, Ernst R. and
Goepferich, Achim 
(2022)
A single intravenous injection of cyclosporin A–loaded lipid nanocapsules prevents retinopathy of prematurity.
Science Advances 8 (38).
Heinl, Elena-Sofia,
Lorenz, Sebastian,
Schmidt, Barbara 
,
Laqtom, Nouf Nasser M.,
Mazzulli, Joseph R.,
Francelle, Laetitia,
Yu, Timothy W.,
Greenberg, Benjamin,
Storch, Stephan,
Tegtmeier, Ines,
Othmen, Helga,
Maurer, Katja,
Steinfurth, Malin,
Witzgall, Ralph 
,
Milenkovic, Vladimir M. 
,
Wetzel, Christian H. 
and
Reichold, Markus
(2022)
CLN7/MFSD8 may be an important factor for SARS-CoV-2 cell entry.
iScience 25 (10), p. 105082.
Dorn, Christoph 
,
Petroff, David,
Kratzer, Alexander,
Kees, Frieder 
,
Kloft, Charlotte,
Zeitlinger, Markus,
Wrigge, Hermann and
Simon, Philipp
(2022)
Tigecycline Soft Tissue Penetration in Obese and Non-obese Surgical Patients Determined by Using In Vivo Microdialysis.
European Journal of Drug Metabolism and Pharmacokinetics 47, pp. 749-755.
Meurer, Florian 
,
Dolomanov, Oleg V.,
Hennig, Christoph,
Peyerimhoff, Norbert,
Kleemiss, Florian 
,
Puschmann, Horst and
Bodensteiner, Michael 
(2022)
Refinement of anomalous dispersion correction parameters in single-crystal structure determinations.
IUCrJ / International Union of Crystallography 9 (5), pp. 604-609.
Bresinsky, Merlin,
Strasser, Jessica M.,
Hubmann, Alexander,
Vallaster, Bernadette,
McCue, William M.,
Fuller, Jessica,
Singh, Gurpreet,
Nelson, Kathryn M.,
Cuellar, Matthew E.,
Finzel, Barry C.,
Ashe, Karen H.,
Walters, Michael A. and
Pockes, Steffen 
(2022)
Characterization of caspase‐2 inhibitors based on specific sites of caspase‐2‐mediated proteolysis.
Archiv der Pharmazie 355 (9), p. 2200095.
Jorda, Anselm 
,
Wulkersdorfer, Beatrix,
Schörgenhofer, Christian,
Matzneller, Peter 
,
Al Jalali, Valentin 
,
Bauer, Martin,
Wölf-Duchek, Michael,
Lackner, Edith,
Dorn, Christoph 
,
Jilma, Bernd 
and
Zeitlinger, Markus
(2022)
Influence of tedizolid on the cytokine response to the endotoxin challenge in healthy volunteers: a cross-over trial.
Journal of Antimicrobial Chemotherapy.
Fulltext not available.
Ousingsawat, Jiraporn 
,
Centeio, Raquel,
Cabrita, Inês 
,
Talbi, Khaoula,
Zimmer, Oliver 
,
Graf, Moritz,
Göpferich, Achim 
,
Schreiber, Rainer 
and
Kunzelmann, Karl 
(2022)
Airway Delivery of Hydrogel-Encapsulated Niclosamide for the Treatment of Inflammatory Airway Disease.
International Journal of Molecular Sciences 23 (3), p. 1085.
Rösch, Gundula,
Muschter, Dominique 
,
Taheri, Shahed,
El Bagdadi, Karima,
Dorn, Christoph 
,
Meurer, Andrea,
Zaucke, Frank,
Schilling, Arndt F.,
Grässel, Susanne 
,
Straub, Rainer H. 
and
Jenei-Lanzl, Zsuzsa
(2022)
β2-Adrenoceptor Deficiency Results in Increased Calcified Cartilage Thickness and Subchondral Bone Remodeling in Murine Experimental Osteoarthritis.
Frontiers in Immunology 12.
Peterhoff, David 
,
Thalhauser, Stefanie,
Neckermann, Patrick,
Barbey, Clara,
Straub, Kristina 
,
Nazet, Julian,
Merkl, Rainer 
,
Längst, Gernot 
,
Breunig, Miriam 
and
Wagner, Ralf 
(2022)
Multivalent display of engineered HIV-1 envelope trimers on silica nanoparticles for targeting and in vitro activation of germline VRC01 B cells.
European Journal of Pharmaceutics and Biopharmaceutics 181, pp. 88-101.
Fulltext not available.
Mietzner, Raphael 
,
Pawlak, Ramona,
Tamm, Ernst R. 
,
Goepferich, Achim 
,
Fuchshofer, Rudolf 
and
Breunig, Miriam 
(2021)
Angiopoietin-1 Mimetic Nanoparticles for Restoring the Function of Endothelial Cells as Potential Therapeutic for Glaucoma.
Pharmaceuticals 15 (1), p. 18.
Busse, David,
Simon, Philipp,
Schmitt, Lisa,
Petroff, David,
Dorn, Christoph 
,
Dietrich, Arne,
Zeitlinger, Markus,
Huisinga, Wilhelm,
Michelet, Robin,
Wrigge, Hermann and
Kloft, Charlotte
(2021)
Comparative Plasma and Interstitial Tissue Fluid Pharmacokinetics of Meropenem Demonstrate the Need for Increasing Dose and Infusion Duration in Obese and Non-obese Patients.
Clinical Pharmacokinetics.
Dorn, Christoph 
(2021)
3.3. Informationen über Arzneimittel.
In:
Sax, Michael, (ed.)
Pharmazie für die Praxis : Lehrbuch für Pharmazeuten im Praktikum : Handbuch für die Apotheke.
Deutscher Apotheker Verlag, Stuttgart, pp. 152-173.
ISBN 978-3-7692-7010-5.
Fulltext not available.
Rösch, Gundula,
El Bagdadi, Karima,
Muschter, Dominique 
,
Taheri, Shahed,
Dorn, Christoph 
,
Meurer, Andrea,
Straub, Rainer H. 
,
Zaucke, Frank 
,
Schilling, Arndt F.,
Grässel, Susanne 
and
Jenei-Lanzl, Zsuzsa
(2021)
Sympathectomy aggravates subchondral bone changes during osteoarthritis progression in mice without affecting cartilage degeneration or synovial inflammation.
Osteoarthritis and Cartilage 30 (3), pp. 461-474.
Fulltext not available.
Busse, David,
Borghardt, Jens Markus,
Petroff, David,
Pevzner, Alice,
Dorn, Christoph 
,
El‐Najjar, Nahed,
Huisinga, Wilhelm,
Wrigge, Hermann,
Simon, Philipp and
Kloft, Charlotte
(2021)
EVALUATING PREDICTION METHODS FOR GLOMERULAR FILTRATION TO OPTIMISE DRUG DOSES IN OBESE AND NON‐OBESE PATIENTS.
British Journal of Clinical Pharmacology.
Fulltext not available.
Busse, David,
Simon, Philipp,
Petroff, David,
Dorn, Christoph 
,
Schmitt, Lisa,
Bindellini, Davide,
Kratzer, Alexander,
Dietrich, Arne,
Zeitlinger, Markus,
Huisinga, Wilhelm,
Michelet, Robin,
Wrigge, Hermann and
Kloft, Charlotte
(2021)
Similar Piperacillin/Tazobactam Target Attainment in Obese versus Nonobese Patients despite Differences in Interstitial Tissue Fluid Pharmacokinetics.
Pharmaceutics 13 (9), p. 1380.
Peterhoff, David 
,
Thalhauser, Stefanie,
Sobczak, Jan M.,
Mohsen, Mona O.,
Voigt, Christoph,
Seifert, Nicole 
,
Neckermann, Patrick,
Hauser, Alexandra 
,
Ding, Song,
Sattentau, Quentin,
Bachmann, Martin F. 
,
Breunig, Miriam 
and
Wagner, Ralf
(2021)
Augmenting the Immune Response against a Stabilized HIV-1 Clade C Envelope Trimer by Silica Nanoparticle Delivery.
Vaccines 9 (642), pp. 1-24.
Rosier, Niklas,
Grätz, Lukas,
Schihada, Hannes,
Möller, Jan,
Işbilir, Ali,
Humphrys, Laura J.,
Nagl, Martin,
Seibel, Ulla,
Lohse, Martin J. and
Pockes, Steffen 
(2021)
A Versatile Sub-Nanomolar Fluorescent Ligand Enables NanoBRET Binding Studies and Single-Molecule Microscopy at the Histamine H3 Receptor.
Journal of Medicinal Chemistry 64 (15), pp. 11695-11708.
Fulltext not available.
Tropmann, Katharina,
Bresinsky, Merlin,
Forster, Lisa,
Mönnich, Denise,
Buschauer, Armin 
,
Wittmann, Hans-Joachim,
Hübner, Harald,
Gmeiner, Peter,
Pockes, Steffen 
and
Strasser, Andrea 
(2021)
Abolishing Dopamine D2long/D3 Receptor Affinity of Subtype-Selective Carbamoylguanidine-Type Histamine H2 Receptor Agonists.
Journal of Medicinal Chemistry 64 (12), pp. 8684-8709.
Fulltext not available.
Gergs, Ulrich,
Büxel, Maren L.,
Bresinsky, Merlin,
Kirchhefer, Uwe,
Fehse, Charlotte,
Höring, Carina,
Hofmann, Britt,
Marušáková, Margaréta,
Čináková, Aneta,
Schwarz, Rebecca,
Pockes, Steffen 
and
Neumann, Joachim
(2021)
Cardiac Effects of Novel Histamine H2 Receptor Agonists.
Journal of Pharmacology and Experimental Therapeutics 379 (3), pp. 223-234.
Fulltext not available.
Dorn, Christoph 
,
Petroff, David,
Stoelzel, Melanie,
Kees, Martin G. 
,
Kratzer, Alexander,
Dietrich, Arne,
Kloft, Charlotte,
Zeitlinger, Markus,
Kees, Frieder 
,
Wrigge, Hermann and
Simon, Philipp
(2021)
Perioperative administration of cefazolin and metronidazole in obese and non-obese patients: a pharmacokinetic study in plasma and interstitial fluid.
Journal of Antimicrobial Chemotherapy.
Fulltext not available.
Biselli, Sabrina,
Bresinsky, Merlin,
Tropmann, Katharina 
,
Forster, Lisa,
Honisch, Claudia,
Buschauer, Armin 
,
Bernhardt, Günther 
and
Pockes, Steffen 
(2021)
Pharmacological characterization of a new series of carbamoylguanidines reveals potent agonism at the H2R and D3R.
European Journal of Medicinal Chemistry 214, p. 113190.
Fulltext not available.
Al Jalali, V. 
,
Wölfl-Duchek, M.,
Taubert, M. 
,
Matzneller, P. 
,
Lackner, E.,
Dorn, Christoph 
,
Kratzer, A.,
Wulkersdorfer, B.,
Österreicher, Z and
Zeitlinger, Markus
(2021)
Plasma and soft tissue pharmacokinetics of ceftolozane/tazobactam in healthy volunteers after single and multiple intravenous infusion: a microdialysis study.
Journal of Antimicrobial Chemotherapy.
Fulltext not available.
Wulkersdorfer, Beatrix,
Wicha, Sebastian G.,
Kurdina, Elizaveta,
Carrion Carrera, Stephan F.,
Matzneller, Peter,
Al Jalali, Valentin,
Vossen, Matthias G.,
Riesenhuber, Sonja,
Lackner, Edith,
Dorn, Christoph 
and
Zeitlinger, Markus
(2021)
Protein binding of clindamycin in vivo by means of intravascular microdialysis in healthy volunteers.
Journal of Antimicrobial Chemotherapy.
Fulltext not available.
Szczepańska, Katarzyna,
Pockes, Steffen 
,
Podlewska, Sabina,
Höring, Carina 
,
Mika, Kamil,
Latacz, Gniewomir,
Bednarski, Marek,
Siwek, Agata,
Karcz, Tadeusz,
Nagl, Martin,
Bresinsky, Merlin,
Mönnich, Denise,
Seibel, Ulla,
Kuder, Kamil J.,
Kotańska, Magdalena,
Stark, Holger,
Elz, Sigurd 
and
Kieć-Kononowicz, Katarzyna
(2021)
Structural modifications in the distal, regulatory region of histamine H3 receptor antagonists leading to the identification of a potent anti-obesity agent.
European Journal of Medicinal Chemistry 213, p. 113041.
Fulltext not available.
Höring, Carina 
,
Seibel, Ulla 
,
Tropmann, Katharina,
Grätz, Lukas 
,
Mönnich, Denise 
,
Pitzl, Sebastian,
Bernhardt, Günther 
,
Pockes, Steffen 
and
Strasser, Andrea
(2020)
A Dynamic, Split-Luciferase-Based Mini-G Protein Sensor to Functionally Characterize Ligands at All Four Histamine Receptor Subtypes.
International Journal of Molecular Sciences 21 (22), p. 8440.
Simeth, Nadja Anita 
,
Kinateder, Thomas 
,
Rajendran, Chitra,
Nazet, Julian,
Merkl, Rainer 
,
Sterner, Reinhard 
,
König, Burkhard 
and
Kneuttinger, Andrea C. 
(2020)
Towards Photochromic Azobenzene‐Based Inhibitors for Tryptophan Synthase.
Chemistry—A European Journal 27, pp. 2439-2451.
Grätz, Lukas,
Tropmann, Katharina,
Bresinsky, Merlin,
Müller, Christoph,
Bernhardt, Günther 
and
Pockes, Steffen
(2020)
NanoBRET binding assay for histamine H2 receptor ligands using live recombinant HEK293T cells.
Scientific Reports 10, p. 13288.
Mietzner, Raphael 
,
Kade, Christian,
Froemel, Franziska,
Pauly, Diana,
Stamer, W. Daniel,
Ohlmann, Andreas,
Wegener, Joachim,
Fuchshofer, Rudolf and
Breunig, Miriam 
(2020)
Fasudil Loaded PLGA Microspheres as Potential Intravitreal Depot Formulation for Glaucoma Therapy.
Pharmaceutics 12 (8), p. 706.
Bartole, Edith,
Grätz, Lukas,
Littmann, Timo,
Wifling, David 
,
Seibel, Ulla,
Buschauer, Armin 
and
Bernhardt, Günther
(2020)
UR-DEBa242: A Py-5-Labeled Fluorescent Multipurpose Probe for Investigations on the Histamine H3 and H4 Receptors.
Journal of Medicinal Chemistry 63 (10), pp. 5297-5311.
Fulltext not available.
Maslanka Figueroa, Sara 
,
Fleischmann, Daniel,
Beck, Sebastian,
Tauber, Philipp,
Witzgall, Ralph,
Schweda, Frank and
Goepferich, Achim
(2020)
Nanoparticles Mimicking Viral Cell Recognition Strategies Are Superior Transporters into Mesangial Cells.
Advanced Science 7 (11), p. 1903204.
Dorn, Christoph 
,
Schießer, Selina,
Wulkersdorfer, Beatrix,
Hitzenbichler, Florian,
Kees, Martin G. 
and
Zeitlinger, Markus
(2020)
Determination of free clindamycin, flucloxacillin or tedizolid in plasma: Keep attention to physiological conditions when using ultrafiltration.
Biomedical Chromatography 34, e4820.
Koehler, Katrin,
Hmida, Dorra,
Schlossmann, Jens,
Landgraf, Dana,
Reisch, Nicole,
Schuelke, Markus and
Huebner, Angela
(2020)
Homozygous mutation in murine retrovirus integration site 1 gene associated with a non‐syndromic form of isolated familial achalasia.
Neurogastroenterology & Motility 32 (12).
Fulltext not available.
Sellmer, Andreas,
Pilsl, Bernadette,
Beyer, Mandy,
Pongratz, Herwig,
Wirth, Lukas,
Elz, Sigurd,
Dove, Stefan,
Henninger, Sven Julian,
Spiekermann, Karsten,
Polzer, Harald,
Klaeger, Susan,
Kuster, Bernhard,
Böhmer, Frank D.,
Fiebig, Heinz-Herbert,
Krämer, Oliver H. and
Mahboobi, Siavosh
(2020)
A series of novel aryl-methanone derivatives as inhibitors of FMS-like tyrosine kinase 3 (FLT3) in FLT3-ITD-positive acute myeloid leukemia.
European Journal of Medicinal Chemistry 193, p. 112232.
Fulltext not available.
Fleischmann, Daniel,
Maslanka-Figueroa, Sara,
Beck, Sebastian,
Abstiens, Kathrin,
Witzgall, Ralph,
Schweda, Frank,
Tauber, Philipp and
Goepferich, Achim 
(2020)
Adenovirus-Mimetic Nanoparticles: Sequential Ligand-Receptor Interplay as a Universal Tool for Enhanced In Vitro/In Vivo Cell Identification.
ACS Applied Materials & Interfaces 12 (31), pp. 34689-34702.
Fulltext not available.
Spinnler, Katrin,
von Krüchten, Lara,
Konieczny, Adam,
Schindler, Lisa,
Bernhardt, Günther and
Keller, Max
(2020)
An Alkyne-functionalized Arginine for Solid-Phase Synthesis Enabling “Bioorthogonal” Peptide Conjugation.
ACS Medicinal Chemistry Letters 11 (3), pp. 334-339.
Fulltext not available.
Weber, Laura,
Kuck, Katrin,
Jürgenliemk, Guido,
Heilmann, Jörg,
Lipowicz, Bartosz and
Vissiennon, Cica 
(2020)
Anti-Inflammatory and Barrier-Stabilising Effects of Myrrh, Coffee Charcoal and Chamomile Flower Extract in a Co-Culture Cell Model of the Intestinal Mucosa.
Biomolecules 10 (7), p. 1033.
Fulltext not available.
Ullah, Sami,
Beer, Ronny,
Fuhr, Uwe,
Taubert, Max 
,
Zeitlinger, Markus,
Kratzer, Alexander,
Dorn, Christoph,
Arshad, Usman,
Kofler, Mario and
Helbok, Raimund
(2020)
Brain Exposure to Piperacillin in Acute Hemorrhagic Stroke Patients Assessed by Cerebral Microdialysis and Population Pharmacokinetics.
Neurocritical Care.
Liebchen, Uwe,
Dorn, Christoph 
,
Kees, Martin,
Schiesser, Selina,
Hitzenbichler, Florian,
Kees, Frieder and
Paal, Michael
(2020)
Comment on “Meropenem, Cefepime, and Piperacillin Protein Binding in Patient Samples”.
Therapeutic Drug Monitoring 42 (6), pp. 909-910.
Fulltext not available.
Bohley, Marilena S.,
Birch, Emily,
Baumann, Felix J.,
Dillinger, Andrea E.,
Tamm, Ernst R. and
Goepferich, Achim M.
(2020)
Design of dye and superparamagnetic iron oxide nanoparticle loaded lipid nanocapsules with dual detectability in vitro and in vivo.
International Journal of Pharmaceutics 585, p. 119433.
Fulltext not available.
Schihada, Hannes 
,
Ma, Xiaoyuan,
Zabel, Ulrike,
Vischer, Henry F.,
Schulte, Gunnar 
,
Leurs, Rob,
Pockes, Steffen 
and
Lohse, Martin J. 
(2020)
Development of a Conformational Histamine H3 Receptor Biosensor for the Synchronous Screening of Agonists and Inverse Agonists.
ACS Sensors 5 (6), pp. 1734-1742.
Fulltext not available.
Gruber, Corinna G.,
Pegoli, Andrea,
Müller, Christoph,
Grätz, Lukas,
She, Xueke and
Keller, Max
(2020)
Differently fluorescence-labelled dibenzodiazepinone-type muscarinic acetylcholine receptor ligands with high M2R affinity.
RSC Medicinal Chemistry 11 (7), pp. 823-832.
Fulltext not available.
Andreev, Stanislav,
Pantsar, Tatu 
,
El-Gokha, Ahmed,
Ansideri, Francesco,
Kudolo, Mark,
Anton, Débora Bublitz,
Sita, Giulia 
,
Romasco, Jenny,
Geibel, Christian,
Lämmerhofer, Michael 
,
Goettert, Márcia Ines,
Tarozzi, Andrea,
Laufer, Stefan A. and
Koch, Pierre
(2020)
Discovery and Evaluation of Enantiopure 9H-pyrimido[4,5-b]indoles as Nanomolar GSK-3β Inhibitors with Improved Metabolic Stability.
International Journal of Molecular Sciences 21 (21), p. 7823.
Fulltext not available.
Keller, Max,
Mahuroof, Shahani A.,
Hong Yee, Vivyanne,
Carpenter, Jessica,
Schindler, Lisa,
Littmann, Timo,
Pegoli, Andrea,
Hübner, Harald,
Bernhardt, Günther,
Gmeiner, Peter 
and
Holliday, Nicholas D. 
(2020)
Fluorescence Labeling of Neurotensin(8–13) via Arginine Residues Gives Molecular Tools with High Receptor Affinity.
ACS Medicinal Chemistry Letters 11 (1), pp. 16-22.
Fulltext not available.
Biselli, Sabrina,
Alencastre, Inês,
Tropmann, Katharina,
Erdmann, Daniela,
Chen, Mengya,
Littmann, Timo,
Maia, André F. 
,
Gomez-Lazaro, Maria,
Tanaka, Miho,
Ozawa, Takeaki,
Keller, Max,
Lamghari, Meriem,
Buschauer, Armin and
Bernhardt, Günther
(2020)
Fluorescent H2 Receptor Squaramide-Type Antagonists: Synthesis, Characterization, and Applications.
ACS Medicinal Chemistry Letters 11 (8), pp. 1521-1528.
Fulltext not available.
Abdellatif, Ahmed 
,
Hennig, Robert,
Pollinger, Klaus,
Tawfeek, Hesham,
Goepferich, Achim and
make_name_string expected hash reference
(2020)
Fluorescent Nanoparticles Coated with a Somatostatin Analogue Target Blood Monocyte for Efficient Leukaemia Treatment.
Pharmaceutical Research 37 (11), p. 2017.
Sommer, Judith,
Dorn, Christoph 
,
Gäbele, Erwin,
Bataille, Frauke,
Freese, Kim,
Seitz, Tatjana,
Thasler, Wolfgang E.,
Büttner, Reinhard,
Weiskirchen, Ralf 
,
Bosserhoff, Anja 
and
Hellerbrand, Claus
(2020)
Four-And-A-Half LIM-Domain Protein 2 (FHL2) Deficiency Aggravates Cholestatic Liver Injury.
Cells 9 (1), p. 248.
Apaolaza, P.S. 
,
Busch, M.,
Asin-Prieto, E. 
,
Peynshaert, K. 
,
Rathod, R.,
Remaut, K.,
Dünker, N. and
Göpferich, A.
(2020)
Hyaluronic acid coating of gold nanoparticles for intraocular drug delivery: Evaluation of the surface properties and effect on their distribution.
Experimental Eye Research 198, p. 108151.
Fulltext not available.
Biswas, Siladitta,
Kojonazarov, Baktybek,
Hadzic, Stefan,
Majer, Michael,
Bajraktari, Ganimete,
Novoyatleva, Tatyana,
Ghofrani, Hossein Ardeschir,
Grimminger, Friedrich,
Seeger, Werner,
Weissmann, Norbert,
Schlossmann, Jens and
Schermuly, Ralph Theo
(2020)
IRAG1 Deficient Mice Develop PKG1β Dependent Pulmonary Hypertension.
Cells 9 (10), p. 2280.
Fulltext not available.
Yagati, Ajay Kumar 
,
Behrent, Arne,
Beck, Sebastian,
Rink, Simone,
Goepferich, Achim M.,
Min, Junhong 
,
Lee, Min-Ho 
and
Baeumner, Antje J. 
(2020)
Laser-induced graphene interdigitated electrodes for label-free or nanolabel-enhanced highly sensitive capacitive aptamer-based biosensors.
Biosensors and Bioelectronics 164, p. 112272.
Fulltext not available.
Simon, Philipp 
,
Busse, David 
,
Petroff, David 
,
Dorn, Christoph 
,
Ehmann, Lisa,
Hochstädt, Sophie,
Girrbach, Felix,
Dietrich, Arne,
Zeitlinger, Markus,
Kees, Frieder,
Kloft, Charlotte and
Wrigge, Hermann
(2020)
Linezolid Concentrations in Plasma and Subcutaneous Tissue are Reduced in Obese Patients, Resulting in a Higher Risk of Underdosing in Critically Ill Patients: A Controlled Clinical Pharmacokinetic Study.
Journal of Clinical Medicine 9 (4), p. 1067.
Schießer, Selina,
Hitzenbichler, Florian,
Kees, Martin Georg,
Kratzer, Alexander,
Lubnow, Matthias 
,
Salzberger, Bernd 
,
Kees, Frieder 
and
Dorn, Christoph 
(2020)
Measurement of Free Plasma Concentrations of Beta-Lactam Antibiotics.
Therapeutic Drug Monitoring Publ.Ahead.
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Radiolabeled Dibenzodiazepinone-Type Antagonists Give Evidence of Dualsteric Binding at the M2 Muscarinic Acetylcholine Receptor.
Journal of Medicinal Chemistry 60 (8), pp. 3314-3334.
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Lieb, Sebastian,
Littmann, Timo,
Plank, Nicole,
Felixberger, Johannes,
Tanaka, Miho,
Schäfer, Thorsten,
Krief, Stéphane,
Elz, Sigurd,
Friedland, Kristina,
Bernhardt, Günther,
Wegener, Joachim,
Ozawa, Takeaki and
Buschauer, Armin
(2016)
Label-free versus conventional cellular assays: functional investigations on the human histamine H1 receptor.
Pharmacological Research 114, pp. 13-26.
Fulltext not available.
Töpper, Christoph,
Steinbach, Cathérine Louise,
Dorn, Christoph 
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Kratzer, Alexander,
Wicha, Sebastian G.,
Schleibinger, Michael,
Liebchen, Uwe,
Kees, Frieder,
Salzberger, Bernd and
Kees, Martin G.
(2016)
Variable linezolid exposure in ICU patients—possible role of drug-drug interactions.
Therapeutic Drug Monitoring 38 (5), pp. 573-578.
Fulltext not available.
Naporra, Franziska,
Gobleder, Susanne,
Wittmann, Hans-Joachim,
Spindler, Julia,
Bodensteiner, Michael,
Bernhardt, Günther,
Hübner, Harald,
Gmeiner, Peter,
Elz, Sigurd and
Strasser, Andrea
(2016)
Dibenzo[b,f][1,4]oxazepines and dibenzo[b,e]oxepines: Influence of the chlorine substitution pattern on the pharmacology at the H1R, H4R, 5-HT2AR and other selected GPCRs.
Pharmacological Research 113, pp. 610-625.
(In Press)
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Schlossmann, Jens,
Wetzl, Veronika,
Schinner, Elisabeth,
Kees, Frieder K.,
Hofmann, Franz and
Faerber, Lothar 
(2016)
Involvement of cyclic guanosine monophosphate-dependent protein kinase I in renal antifibrotic effects of serelaxin.
Frontiers in Pharmacology 7 (195), pp. 1-27.
Kuhn, Kilian K.,
Ertl, Thomas,
Dukorn, Stefanie,
Keller, Max,
Bernhardt, Günther,
Reiser, Oliver 
and
Buschauer, Armin
(2016)
High affinity agonists of the neuropeptide Y (NPY) Y4 receptor derived from the C-terminal pentapeptide of human pancreatic polypeptide (hPP): synthesis, stereochemical discrimination and radiolabeling.
Journal of Medicinal Chemistry 59 (13), pp. 6045-6058.
Fulltext not available.
Edalat, Lena,
Stegen, Benjamin,
Klumpp, Lukas,
Haehl, Erik,
Schilbach, Karin,
Lukowski, Robert,
Kühnle, Matthias,
Bernhardt, Günther,
Buschauer, Armin,
Zips, Daniel,
Ruth, Peter and
Huber, Stephan M.
(2016)
BK K+ channel blockade inhibits radiation-induced migration/brain infiltration of glioblastoma cells.
Oncotarget 7 (12), pp. 14259-14278.
Fulltext not available.
Lorenz, Peter,
Knittel, Diana N.,
Conrad, Jürgen,
Lotter, Eva M.,
Heilmann, Jörg,
Stintzing, Florian C. and
Kammerer, Dietmar R.
(2016)
1-Acetyl-3-[(3R)-hydroxyfatty acyl]glycerols: Lipid Compounds fromEuphrasia rostkovianaHayneandE. tetraquetra(Bréb.)Arrond.
Chemistry & Biodiversity 13 (5), pp. 602-612.
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Hammer, Sebastian,
Gobleder, Susanne,
Naporra, Franziska,
Wittmann, Hans-Joachim,
Elz, Sigurd,
Heinrich, Markus 
and
Strasser, Andrea
(2016)
2,4-Diaminopyrimidines as dual ligands at the histamine H1 and H4 receptor - H1/H4-receptor selectivity.
Bioorganic & Medicinal Chemistry Letters 26, pp. 292-300.
Fulltext not available.
Dolles, Dominik,
Nimczick, Martin,
Scheiner, Matthias,
Ramler, Jacqueline,
Stadtmüller, Patricia,
Sawatzky, Edgar,
Drakopoulos, Antonios,
Sotriffer, Christoph,
Wittmann, Hans-Joachim,
Strasser, Andrea and
Decker, Michael
(2016)
Aminobenzimidazoles and structural isomers as templates for dual-acting butyrylcholinesterase inhibitors and hCB2R ligands to combat neurodegenerative disorders.
ChemMedChem 11 (12), pp. 1270-1283.
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Bucher, Felicitas 
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Walz, Johanna M.,
Bühler, Anima,
Aguilar, Edith,
Lange, Clemens,
Diaz-Aguilar, Sophia,
Martin, Gottfried,
Schlunck, Günther,
Agostini, Hansjürgen,
Friedlander, Martin and
Stahl, Andreas
(2016)
CNTF Attenuates Vasoproliferative Changes Through Upregulation of SOCS3 in a Mouse-Model of Oxygen-Induced Retinopathy.
Investigative Opthalmology & Visual Science 57 (10), p. 4017.
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Sawatzky, Edgar,
Wehle, Sarah,
Kling, Beata,
Wendrich, Jan,
Bringmann, Gerhard,
Sotriffer, Christoph A.,
Heilmann, Jörg and
Decker, Michael
(2016)
Discovery of Highly Selective and Nanomolar Carbamate-Based Butyrylcholinesterase Inhibitors by Rational Investigation into Their Inhibition Mode.
Journal of Medicinal Chemistry 59 (5), pp. 2067-2082.
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Kariminia, Amina,
Holtan, Shernan G.,
Ivison, Sabine,
Rozmus, Jacob,
Hebert, Marie-Josée,
Martin, Paul J.,
Lee, Stephanie J.,
Wolff, Daniel,
Subrt, Peter,
Abdossamadi, Sayeh,
Sung, Susanna,
Storek, Jan,
Levings, Megan,
Aljurf, Mahmoud,
Arora, Mukta,
Cutler, Corey,
Gallagher, Geneviève,
Kuruvilla, John,
Lipton, Jeff,
Nevill, Thomas J.,
Newell, Laura F.,
Panzarella, Tony,
Pidala, Joseph,
Popradi, Gizelle,
Szwajcer, David,
Tay, Jason 
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Toze, Cynthia L.,
Walker, Irwin,
Couban, Stephen,
Storer, Barry E. and
Schultz, Kirk R. 
(2016)
Heterogeneity of chronic graft-versus-host disease biomarkers: association with CXCL10 and CXCR3+ NK cells.
Blood 127 (24), pp. 3082-3091.
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Dove, Stefan
(2016)
Mammalian Nucleotidyl Cyclases and Their Nucleotide Binding Sites.
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Non-canonical Cyclic Nucleotides.
Handbook of Experimental Pharmacology, 238.
Springer International Publishing, Cham, Switzerland, pp. 49-66.
ISBN 978-3-319-52673-7 (online), 978-3-319-52671-3 (print).
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Keller, Max,
Kuhn, Kilian K.,
Einsiedel, Jürgen,
Hübner, Harald,
Biselli, Sabrina,
Mollereau, Catherine 
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Wifling, David,
Svobodova, Jaroslava,
Bernhardt, Günther,
Cabrele, Chiara 
,
Vanderheyden, Patrick,
Gmeiner, Peter 
and
Buschauer, Armin
(2016)
Mimicking of arginine by functionalized Nω-carbamoylated arginine as a new broadly applicable approach to labeled bioactive peptides: high affinity angiotensin, neuropeptide Y, neuropeptide FF and neurotensin receptor ligands as examples.
Journal of Medicinal Chemistry 59 (5), pp. 1925-1945.
Fulltext not available.
Khan, Nadia,
Saad, Ali,
Nurulain, Syed M.,
Darras, Fouad H.,
Decker, Michael and
Sadek, Bassem
(2016)
The dual-acting H3 receptor antagonist and AChE inhibitor UW-MD-71 dose-dependently enhances memory retrieval and reverses dizocilpine-induced memory impairment in rats.
Behavioural Brain Research 297, pp. 155-164.
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Huang, Guozheng 
,
Schramm, Simon,
Heilmann, Jörg,
Biedermann, David,
Křen, Vladimír and
Decker, Michael
(2016)
Unconventional application of the Mitsunobu reaction: Selective flavonolignan dehydration yielding hydnocarpins.
Beilstein Journal of Organic Chemistry 12, pp. 662-669.
Fulltext not available.
Werner, Kristin,
Kälble, Solveig,
Wolter, Sabine,
Schneider, Erich H.,
Buschauer, Armin,
Neumann, Detlef and
Seifert, Roland
(2015)
Flow cytometric analysis with a fluorescent formyl peptide receptor ligand as a new method to study the pharmacological profile of the histamine H2-receptor.
Naunyn Schmiedebergs Archives of Pharmacology 388 (10), pp. 1039-1052.
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Wolferstetter, Stefanie,
Reinders, Jörg,
Schwede, Frank,
Ruth, Peter,
Schinner, Elisabeth and
Schlossmann, Jens
(2015)
Interaction of cCMP with the cGK, cAK and MAPK Kinases in Murine Tissues.
PLoS ONE 10 (5), e0126057.
Baumeister, Paul,
Erdmann, Daniela,
Biselli, Sabrina,
Kagermeier, Nicole,
Elz, Sigurd,
Bernhardt, Günther and
Buschauer, Armin
(2015)
3HUR-DE257: Development of a tritium-labeled squaramide-type selective histamine H2 receptor antagonist.
ChemMedChem 10 (1), pp. 83-93.
Fulltext not available.
Dolles, Dominik,
Nimczick, Martin,
Scheiner, Matthias,
Ramler, Jacqueline,
Stadtmüller, Patricia,
Sawatzky, Edgar,
Drakopoulos, Antonios 
,
Sotriffer, Christoph,
Wittmann, Hans-Joachim,
Strasser, Andrea and
Decker, Michael
(2015)
Aminobenzimidazoles and Structural Isomers as Templates for Dual-Acting Butyrylcholinesterase Inhibitors andhCB2R Ligands To Combat Neurodegenerative Disorders.
ChemMedChem 11 (12), pp. 1270-1283.
Fulltext not available.
Orlando, Zoya,
Lengers, Isabelle,
Melzig, Matthias F.,
Buschauer, Armin,
Hensel, Andreas and
Jose, Joachim
(2015)
Autodisplay of human hyaluronidase Hyal-1 on Escherichia coli and identification of plant-derived enzyme inhibitors.
Molecules 20 (9), pp. 15449-15468.
Kirchhof, Susanne,
Gregoritza, Manuel,
Messmann, Viktoria,
Hammer, Nadine,
Göpferich, Achim and
Brandl, Ferdinand
(2015)
Diels-Alder hydrogels with enhanced stability: First step toward controlled release of bevacizumab.
European Journal of Pharmaceutics and Biopharmaceutics 96, pp. 217-225.
Fulltext not available.
Kirchhof, Susanne,
Abrami, Michela,
Messmann, Viktoria,
Hammer, Nadine,
Goepferich, Achim,
Grassi, Mario and
Brandl, Ferdinand
(2015)
Diels–Alder hydrogels for controlled antibody release: Correlation between mesh size and release rate.
Molecular Pharmaceutics 12 (9), pp. 3358-3368.
Fulltext not available.
Lübker, Carolin,
Dove, Stefan,
Tang, Wei-Jen,
Bieber Urbauer, Ramona J.,
Moskovitz, Jackob,
Urbauer, Jeffrey L. and
Seifert, Roland
(2015)
Different Roles of N-Terminal and C-Terminal Domains in Calmodulin for Activation of Bacillus anthracis Edema Factor.
Toxins 7 (7), pp. 2598-2614.
Kagermeier, Nicole,
Werner, Kristin,
Keller, Max,
Baumeister, Paul,
Bernhardt, Günther,
Seifert, Roland and
Buschauer, Armin
(2015)
Dimeric carbamoylguanidine-type histamine H2 receptor ligands: A new class of potent and selective agonists.
Bioorganic & Medicinal Chemistry 23 (14), pp. 3957-3969.
Fulltext not available.
Arndt, Stephanie,
Wacker, Eva,
Dorn, Christoph 
,
Koch, Andreas,
Saugspier, Michael,
Thasler, W. E.,
Hartmann, Arndt,
Bosserhoff, Anja-Katrin and
Hellerbrand, Claus
(2015)
Enhanced expression of BMP6 inhibits hepatic fibrosis in non-alcoholic fatty liver disease.
Gut 64 (6), pp. 973-981.
Huber, Stefan,
Huettner, Johannes Philip,
Hacker, Kristina,
Bernhardt, Günther,
König, Jörg and
Buschauer, Armin
(2015)
Esters of bendamustine are by far more potent cytotoxic agents than the parent compound against human sarcoma and carcinoma cells.
PLoS One 10 (7), PLoSe0133743.
Strasser, Andrea and
Buschauer, Armin
(2015)
Histaminrezeptoren.
Pharmakon 3 (2), pp. 109-116.
Fulltext not available.
Kirchhof, Susanne,
Goepferich, Achim and
Brandl, Ferdinand
(2015)
Hydrogels in ophthalmic applications.
European Journal of Pharmaceutics and Biopharmaceutics 95, part B, pp. 227-238.
Fulltext not available.
Keller, Max,
Tränkle, Christian,
She, Xueke,
Pegoli, Andrea,
Bernhardt, Günther,
Buschauer, Armin and
Read, Roger W.
(2015)
M2 subtype preferring dibenzodiazepinone-type muscarinic receptor ligands: effect of chemical homo-dimerization on orthosteric (and allosteric?) binding.
Bioorganic & Medicinal Chemistry 23 (14), pp. 3970-3990.
Fulltext not available.
Lübker, Carolin,
Bieber-Urbauer, Ramona J.,
Moskovitz, Jackob,
Dove, Stefan,
Weisemann, Jasmin,
Fedorova, Maria,
Urbauer, Jeffrey L. and
Seifert, Roland
(2015)
Membranous adenylyl cyclase 1 activation is regulated by oxidation of N- and C-terminal methionine residues in calmodulin.
Biochemical Pharmacology 93 (2), pp. 196-209.
Fulltext not available.
Wifling, David,
Löffel, Karolin,
Nordemann, Uwe,
Strasser, Andrea,
Bernhardt, Günther,
Dove, Stefan,
Seifert, Roland and
Buschauer, Armin
(2015)
Molecular determinants for the high constitutive activity of the human histamine H4 receptor: Functional studies on orthologs and mutants.
British Journal of Pharmacology 172, pp. 785-798.
Fulltext not available.
Kaczor, Agnieszka,
Guixa-Gonzalez, Ramon,
Carrio, Pau,
Poso, Antti,
Dove, Stefan,
Pastor, Manuel and
Selent, Jana
(2015)
Multi-Component Protein - Protein Docking Based Protocol with External Scoring for Modeling Dimers of G Protein-Coupled Receptors.
Molecular Informatics 34 (4), pp. 246-255.
Fulltext not available.
Hennig, Robert,
Ohlmann, Andreas,
Staffel, Janina,
Pollinger, Klaus,
Haunberger, Alexandra,
Breunig, Miriam,
Schweda, Frank,
Tamm, Ernst R. and
Goepferich, Achim
(2015)
Multivalent nanoparticles bind the retinal and choroidal vasculature.
Journal of Controlled Release 220 (Part A), pp. 265-274.
Fulltext not available.
Keller, Max,
Weiss, Stefan,
Hutzler, Christoph,
Kuhn, Kilian K.,
Mollereau, Catherine,
Dukorn, Stefanie,
Schindler, Lisa,
Bernhardt, Günther,
König, Burkhard and
Buschauer, Armin
(2015)
N(omega)-carbamoylation of the argininamide moiety: an avenue to insurmountable NPY Y1 receptor antagonists and a radiolabeled selective high affinity molecular tool ([3H]UR-MK299) with extended residence time.
Journal of Medicinal Chemistry 58 (22), pp. 8834-8849.
Fulltext not available.
Kirchhof, Susanne,
Strasser, Andrea,
Wittmann, Hans-Joachim,
Messmann, Viktoria,
Hammer, Nadine,
Goepferich, Achim and
Brandl, Ferdinand
(2015)
New insights into the cross-linking and degradation mechanism of Diels–Alder hydrogels.
Journal of Materials Chemistry B 3, pp. 449-457.
Huber, Stefan,
Antoni, Frauke,
Schickaneder, Christian,
Schickaneder, Helmut,
Bernhardt, Günther and
Buschauer, Armin
(2015)
Stabilities of neutral and basic esters of bendamustine in plasma compared to the parent compound: Kinetic investigations by HPLC.
Journal of Pharmaceutical and Biomedical Analysis 104, pp. 137-143.
Fulltext not available.
Reinartz, Michael T.,
Kälble, Solveig,
Littmann, Timo,
Ozawa, Takeaki,
Dove, Stefan,
Kaever, Volkhard,
Wainer, Irving W. and
Seifert, Roland
(2015)
Structure-bias relationships for fenoterol stereoisomers in six molecular and cellular assays at the β2-adrenoceptor.
Naunyn-Schmiedeberg's archives of pharmacology 388 (1), pp. 51-65.
Fulltext not available.
Untergehrer, Monika,
Bücherl, Daniel,
Wittmann, Hans-Joachim,
Strasser, Andrea,
Heilmann, Jörg and
Jürgenliemk, Guido
(2015)
Structure-dependent deconjugation of flavonoid glucuronides by human beta-glucuronidase - in vitro and in silico analyses.
Planta Med. 81 (12/13), pp. 1182-1189.
Fulltext not available.
Herrnberger, Leonie,
Hennig, Robert,
Kremer, Werner,
Hellerbrand, Claus,
Goepferich, Achim,
Kalbitzer, Hans Robert and
Tamm, Ernst R.
(2014)
Formation of Fenestrae in Murine Liver Sinusoids Depends on Plasmalemma Vesicle-Associated Protein and Is Required for Lipoprotein Passage.
PLoS ONE 9 (12), e115005.
Cuboni, Serena,
Devigny, Christian,
Hoogeland, Bastiaan,
Strasser, Andrea,
Pomplun, Sebastian,
Hauger, Barbara,
Höfner, Georg,
Wanner, Klaus,
Eder, Matthias,
Buschauer, Armin,
Holsboer, Florian and
Hausch, Felix
(2014)
Loratadine and analogs: Discovery and preliminary SAR of inhibitors of the amino acid transporter B0AT2.
Journal of Medicinal Chemistry 57 (22), pp. 9473-9479.
Fulltext not available.
Slenczka, Alkwin,
Premke, Tobias,
Wirths, Eva-Maria,
Pentlehner, Dominik,
Lehnig, Rudolf,
Richers, Ricarda and
Vdovin, Alexander
(2014)
Microsolvation of Molecules in Superfluid Helium Nanodroplets Revealed by Means of Electronic Spectroscopy.
Frontiers in Chemistry.
Darras, Fouad,
Pockes, Steffen 
,
Huang, Guozheng,
Wehle, Sarah,
Strasser, Andrea,
Wittmann, Hans-Joachim,
Nimczick, Martin,
Sotriffer, Christoph and
Decker, Michael
(2014)
Synthesis, biological evaluation, and computational studies of tri- and tetracyclic nitrogen-bridgehead compounds as potent dual-acting AChE inhibitors and hH3 receptor antagonists.
ACS Chemical Neuroscience 5 (3), pp. 225-242.
Fulltext not available.
Pollinger, Klaus,
Hennig, Robert,
Bauer, Stefanie,
Breunig, Miriam,
Tessmar, Joerg,
Buschauer, Armin,
Witzgall, Ralph and
Göpferich, Achim
(2014)
Biodistribution of quantum dots in the kidney after intravenous injection.
Journal of Nanoscience and Nanotechnology 14 (5), pp. 3313-3319.
Fulltext not available.
Pannem, Rajeswara Rao,
Dorn, Christoph 
,
Ahlqvist, Kristofer,
Bosserhoff, Anja K.,
Hellerbrand, Claus and
Massoumi, Ramin
(2014)
CYLD controls c-MYC expression through the JNK-dependent signaling pathway in hepatocellular carcinoma.
Carcinogenesis 35 (2), pp. 461-468.
Dorn, Christoph 
,
Engelmann, Julia C.,
Saugspier, Michael,
Koch, Andreas,
Hartmann, Arndt,
Müller, Martina,
Spang, Rainer,
Bosserhoff, Anja and
Hellerbrand, Claus
(2014)
Increased expression of c-Jun in nonalcoholic fatty liver disease.
Laboratory Investigation 94 (4), pp. 394-408.
Fulltext not available.
Luschmann, Christoph,
Tessmar, Joerg,
Schoeberl, Simon,
Strauss, O.,
Luschmann, Karl and
Goepferich, Achim
(2014)
Self-assembling colloidal system for the ocular administration of cyclosporine A.
Cornea 33 (1), pp. 77-81.
Fulltext not available.
Geyer, Roland,
Igel, Patrick,
Kaske, Melanie,
Elz, Sigurd and
Buschauer, Armin
(2014)
Synthesis, SAR and selectivity of 2-acyl- and 2-cyano-1-hetarylalkyl-guanidines at the four histamine receptor subtypes: a bioisosteric approach.
MedChemComm 5 (1), pp. 72-81.
Fulltext not available.
Endlich, Nicole,
Simon, Ole,
Goepferich, Achim,
Wegner, Henny,
Moeller, Marcus J.,
Rumpel, Elisabeth,
Kotb, Ahmed and
Endlich, Karlhans
(2014)
Two-Photon Microscopy Reveals Stationary Podocytes in Living Zebrafish Larvae.
Journal of the American Society of Nephrology 25 (4), pp. 681-686.
Fulltext not available.
Schickaneder, Helmut,
Buschauer, Armin,
Bernhardt, Günther,
Schickaneder, Christian,
Limmert, Michael,
Huber, Stefan,
Lubbe, Mathias and
Hofmeier, Harald
(2013)
Esters of bendamustine and related compounds, and medical use thereof.
Fulltext not available.
Schreeb, Annemarie,
Łażewska, Dorota,
Dove, Stefan,
Buschauer, Armin,
Kieć-Kononiwcz, Katarzyna and
Stark, Holger
(2013)
2. Histamine H4 receptor ligands.
In:
Stark, Holger, (ed.)
Histamine H4 receptor: a novel drug target for immunoregulation and inflammation.
Versita, London, pp. 21-62.
ISBN 9788376560564.
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Berlicki, Lukasz,
Kaske, Melanie,
Gutierrez-Abad, Raquel,
Bernhardt, Günther,
Illa, Ona,
Ortuño, Rosa,
Cabrele, Chiara,
Buschauer, Armin and
Reiser, Oliver
(2013)
Replacement of Thr32 and Gln34 in the C-terminal neuropeptide Y fragment 25-36 by cis-cyclobutane- and cis-cyclopentane β-amino acids shifts selectivity toward the Y4 receptor.
Journal of Medicinal Chemistry 56 (21), pp. 8422-8431.
Fulltext not available.
Nordemann, Uwe,
Wifling, David,
Schnell, David,
Bernhardt, Günther,
Stark, Holger,
Seifert, Roland and
Buschauer, Armin
(2013)
Luciferase reporter gene assay on human, murine and rat histamine H4 receptor orthologs: correlations and discrepancies between distal and proximal readouts.
PLoS One 8 (9), e73961.
Bauer, Stefanie,
Ochoa Puentes, Cristian,
Sun, Qiu,
Bause, Manuel,
Bernhardt, Günther,
König, Burkhard and
Buschauer, Armin
(2013)
Quinoline carboxamide-type ABCG2 modulators: Indole and quinoline moieties as anilide replacements.
ChemMedChem 8 (11), pp. 1773-1778.
Fulltext not available.
Brunskole Hummel, Irena,
Kälble, Solveig,
Burhenne, Heike,
Reinartz, Michael T.,
Schwede, Frank,
Buschauer, Armin and
Seifert, Roland
(2013)
Dissociations in the effects of beta2-adrenergic receptor agonists on cAMP formation and superoxide production in human neutrophils: Support for the concept of functional selectivity.
PLoS One 8 (5), e64556.
Zölls, Sarah,
Gregoritza, Manuel,
Tantipolphan, Ruedeeporn,
Wiggenhorn, Michael,
Winter, Gerhard,
Friess, Wolfgang and
Hawe, Andrea
(2013)
How Subvisible Particles Become Invisible - Relevance of the Refractive Index for Protein Particle Analysis.
Journal of Pharmaceutical Sciences 102 (5), pp. 1434-1446.
Fulltext not available.
Kees, Martin Georg,
Schaeftlein, André,
Haeberle, Helene Anna,
Kees, Frieder K.,
Kloft, Charlotte and
Heininger, Alexandra
(2013)
Population pharmacokinetics and pharmacodynamic evaluation of intravenous and enteral moxifloxacin in surgical intensive care unit patients.
The Journal of antimicrobial chemotherapy.
Fulltext not available.
Ochoa-Puentes, Cristian,
Bauer, Stefanie,
Kühnle, Matthias,
Bernhardt, Günther,
Buschauer, Armin and
König, Burkhard
(2013)
Benzanilide – Biphenyl Replacement: A Bioisosteric Approach to Quinoline Carboxamide-type ABCG2 Modulators.
ACS Medicinal Chemistry Letters 4 (4), pp. 393-396.
Fulltext not available.
Seifert, Roland,
Strasser, Andrea,
Schneider, Erich H.,
Neumann, Detlef,
Dove, Stefan and
Buschauer, Armin
(2013)
Molecular and cellular analysis of human histamine receptor subtypes.
Trends in Pharmacological Sciences 34 (1), pp. 33-58.
Fulltext not available.
Krautbauer, Sabrina,
Wanninger, Josef,
Eisinger, Kristina,
Hader, Yvonne,
Beck, Michael,
Kopp, Andrea,
Schmid, Andreas,
Weiss, Thomas S.,
Dorn, Christoph 
and
Buechler, Christa
(2013)
Chemerin is highly expressed in hepatocytes and is induced in non-alcoholic steatohepatitis liver.
Experimental and Molecular Pathology 95 (2), pp. 199-205.
Fulltext not available.
Luschmann, Christoph,
Tessmar, Joerg,
Schoeberl, Simon,
Framme, Carsten,
Luschmann, Karl and
Goepferich, Achim
(2013)
Developing an in situ nanosuspension: A novel approach towards the efficient administration of poorly soluble drugs at the anterior eye.
European Journal of Pharmaceutical Sciences 50 (3-4), pp. 385-392.
Fulltext not available.
Miller, Tobias,
van Colen, G.,
Sander, B.,
Golas, M.,
Uezguen, Senta,
Weigandt, Markus and
Goepferich, Achim
(2013)
Drug Loading of Polymerics Micelles.
Pharmaceutical Research 30 (2), pp. 484-595.
Fulltext not available.
Dietrich, P.,
Moleda, Lukas,
Kees, Frieder K.,
Müller, M.,
Straub, R. H.,
Hellerbrand, C. and
Wiest, R.
(2013)
Dysbalance in sympathetic neurotransmitter release and action in cirrhotic rats: impact of exogenous neuropeptide Y.
Journal of hepatology 58 (2), pp. 254-261.
Fulltext not available.
Ferstl, Matthias,
Drechsler, Markus,
Rachel, Reinhard,
Rischer, M.,
Engel, J.,
Backofen, Michael and
Goepferich, Achim
(2013)
Impact of Polyelectrolyte Structure on the Shape of Nanoassemblies with Cationic Peptides.
European Journal of Pharmaceutical Sciences 102, pp. 2599-2607.
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Mueller, M.,
Blunk, Torsten,
Appel, Bernhard,
Maschke, Angelika,
Goepferich, Achim and
Zellner, J.
(2013)
Insulin is essential for in vitro chondrogenesis of mesenchymal progenitor cells and influences chondrogenesis in a dose-dependent manner.
International orthopaedics 37 (1), pp. 153-158.
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Wurster, Eva-Christina,
Elbakry, Asmaa,
Goepferich, Achim and
Breunig, Miriam
(2013)
Layer-by-layer assembled gold nanoparticles for the delivery of nucleic acids.
In:
Nanotechnology for Nucleic Acid Delivery : Methods and Protocols.
Methods in Molecular Biology, 948.
Humana Press; Springer, Totowa, NJ, pp. 171-182.
ISBN 978-1-62703-139-4 (print), 978-1-627-03140-0 (online).
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Pollinger, Klaus,
Hennig, Robert,
Ohlmann, Andreas,
Fuchshofer, R.,
Wenzel, Rebecca and
Breunig, Miriam
(2013)
Ligand-functionalized nanoparticles target endothelial cells in retinal capillaries after systemic application.
Proceedings of the National Academy of Sciences of the United States of America (PNAS) 25, pp. 6115-6120.
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Schweizer, Daniel,
Voitier, I.,
Heier, A.,
Serno, Tim,
Goepferich, Achim and
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(2013)
Pharmacokinetics, biocompatibility and bioavailability of a controlled release monoclonal antibody formulation.
Journal of Controlled Release 172 (3), pp. 975-982.
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Miller, Tobias,
Breyer, S.,
van Colen, G.,
Mier, W.,
Haberkorn, U.,
Geissler, S.,
Voss, S.,
Weigandt, Markus and
Goepferich, Achim
(2013)
Premature drug release of polymeric micelles and its effects on tumor targeting.
International Journal of Pharmaceutics 445 (1-2), pp. 117-124.
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Göpferich, Achim
(2013)
To pause a moment.
European Journal of Pharmaceutics and Biopharmaceutics 85 (3), p. 328.
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Memminger, Martin,
Keller, Max,
Lopuch, Miroslaw,
Pop, Nathalie,
Bernhardt, Günther,
von Angerer, Erwin and
Buschauer, Armin
(2012)
The Neuropeptide Y Y1 receptor: a diagnostic marker? Expression in MCF-7 breast cancer cells is down-regulated by antiestrogens in vitro and in xenografts.
PLoS ONE 7 (12), e51032.
Löber, Stefan,
Hübner, Harald,
Buschauer, Armin,
Sanna, Fabrizio,
Argiolas, Antonio,
Melis, Maria Rosaria and
Gmeiner, Peter
(2012)
Novel azulene derivatives for the treatment of erectile dysfunction.
Bioorganic & medicinal chemistry letters 22 (23), pp. 7151-7154.
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Birnkammer, Tobias,
Spickenreither, Anja,
Brunskole, Irena,
Lopuch, Miroslaw,
Kagermeier, Nicole,
Bernhardt, Günther,
Dove, Stefan,
Seifert, Roland,
Elz, Sigurd and
Buschauer, Armin
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The bivalent ligand approach leads to highly potent and selective acylguanidine-type histamine H2 receptor agonists.
Journal of Medicinal Chemistry 55 (3), pp. 1147-1160.
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Bauhuber, Sonja,
Liebl, Renate,
Tomasetti, Luise,
Rachel, Reinhard,
Goepferich, Achim and
Breunig, Miriam
(2012)
A library of strictly linear poly(ethylene glycol)-poly(ethylene imine) diblock coploymers to perform structure-function relationship on non-viral gene carriers.
Journal of Controlled Release 162, pp. 446-455.
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Miller, Tobias,
Rachel, Reinhard,
Besheer, Ahmed,
Uezguen, Senta,
Weigand, Markus and
Göpferich, Achim
(2012)
Comparative Investigations on In Vitro Serum Stability of Polymeric Micelle Formulations.
Pharmaceutical Research 29 (2), pp. 448-459.
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Posavec, Damir,
Zabel, Manfred,
Bogner, Udo,
Bernhardt, Günther and
Knör, Günther
(2012)
Functionalized derivatives of 1,4-dimethylnaphthalene as precursors for biomedical applications: synthesis, structures, spectroscopy and photochemical activation in the presence of dioxygen.
Organic & biomolecular chemistry 10 (35), pp. 7062-7069.
Saugspier, Michael,
Dorn, Christoph 
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Thasler, Wolfgang E.,
Gehrig, Manfred,
Heilmann, Jörg and
Hellerbrand, Claus
(2012)
Hop bitter acids exhibit anti-fibrogenic effects on hepatic stellate cells in vitro.
Experimental and Molecular Pathology 92 (2), pp. 222-228.
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Saugspier, Michael,
Dorn, Christoph 
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Czech, Barbara,
Gehrig, Manfred,
Heilmann, Jörg and
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Hop bitter acids inhibit tumorigenicity of hepatocellular carcinoma cells in vitro.
Oncology Reports 28 (4), pp. 1423-1428.
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Appl, Heidrun,
Holzammer, Tobias,
Dove, Stefan,
Haen, Ekkehard,
Strasser, Andrea and
Seifert, Roland
(2012)
Interactions of recombinant human histamine H₁R, H₂R, H₃R, and H₄R receptors with 34 antidepressants and antipsychotics.
Naunyn-Schmiedeberg's archives of pharmacology 385 (2), pp. 145-170.
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Pollinger, Klaus,
Hennig, Robert,
Breunig, Miriam,
Teßmar, Jörg,
Ohlmann, Andreas,
Tamm, Ernst R.,
Witzgall, Ralph and
Goepferich, Achim
(2012)
Kidney Podocytes as Specific Targets for cyclo(RGDfC)-Modified Nanoparticles.
Small 8, pp. 3368-3375.
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Elbakry, Asmaa Mohamed,
Wurster, Eva-Christina,
Zaky, Alaa,
Liebl, Renate,
Schindler, Edith,
Bauer-Kreisel, Petra,
Blunk, Torsten,
Rachel, Reinhard,
Goepferich, Achim and
Breunig, Miriam
(2012)
Layer-by-Layer Coated Gold Nanoparticles: Size-Dependent Delivery of DNA into Cells.
Small 8 (24), pp. 3847-3856.
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Kees, Martin G.,
Steinke, T.,
Moritz, S.,
Rupprecht, K.,
Paulus, E. M.,
Kees, Frieder K.,
Bucher, M. and
Faerber, L.
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Omeprazole impairs the absorption of mycophenolate mofetil but not of enteric-coated mycophenolate sodium in healthy volunteers.
Journal of clinical pharmacology 52 (8), pp. 1265-1272.
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Justinger, Christoph,
Schilling, Martin K.,
Kees, Martin G.,
Kauffels, Anne,
Hirschmann, Katrin,
Kopp, Berit,
Kees, Frieder K. and
Kollmar, Otto
(2012)
Penetration of moxifloxacin into liver tissue.
International journal of antimicrobial agents 39 (6), pp. 505-509.
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Heller, Anne,
Brockhoff, Gero and
Goepferich, Achim
(2012)
Targeting drugs to mitochondria.
European Journal of Pharmaceutics and Biopharmaceutics 82, pp. 1-18.
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Klein, Matthias S.,
Dorn, Christoph 
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Saugspier, Michael Sebastian,
Hellerbrand, Claus,
Oefner, Peter J. and
Gronwald, Wolfram
(2011)
Discrimination of steatosis and NASH in mice using nuclear magnetic resonance spectroscopy.
Metabolomics 7 (2), pp. 237-246.
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Kellermann, K.,
Dertinger, N.,
Blobner, M.,
Kees, Frieder,
Kochs, E. F. and
Jungwirt, B.
(2011)
Perioperative moxifloxacin treatment in rats subjected to deep hypothermic circulatory arrest: reduction in cerebral inflammation but without improvement in cognitive performance.
Journal of Thoracic and Cardiovascular Surgery 141 (3), pp. 796-802.
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Gäbele, Erwin,
Dostert, Karin,
Dorn, Christoph 
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Patsenker, Eleonora,
Stickel, Felix and
Hellerbrand, Claus
(2011)
A New Model of Interactive Effects of Alcohol and High-Fat Diet on Hepatic Fibrosis.
Alcoholism: Clinical and Experimental Research 35 (7), pp. 1361-1367.
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Wanninger, Josef,
Neumeier, Markus,
Bauer, Sabrina,
Weiss, Thomas S.,
Eisinger, Kristina,
Walter, Roland,
Dorn, Christoph 
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Hellerbrand, Claus,
Schäffler, Andreas and
Buechler, Christa
(2011)
Adiponectin induces the transforming growth factor decoy receptor BAMBI in human hepatocytes.
FEBS Letters 585 (9), pp. 1338-1344.
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Kirovski, Georgi,
Dorn, Christoph 
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Huber, Hanna,
Moleda, Lukas,
Niessen, Catrin,
Wobser, Hella,
Schacherer, Doris,
Buechler, Christa,
Wiest, Reiner and
Hellerbrand, Claus
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Elevated systemic monocyte chemoattractrant protein-1 in hepatic steatosis without significant hepatic inflammation.
Experimental and Molecular Pathology 91 (3), pp. 780-783.
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Schaedlich, A.,
Rose, C.,
Kuntsche, J.,
Caysa, H.,
Mueller, T.,
Goepferich, Achim and
Maeder, K.
(2011)
How Stealthy are PEG-PLA Nanoparticles? An NIR In Vivo Study Combined with Detailed Size Measurements.
Pharmaceutical Research 28 (8), pp. 1995-2007.
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Wanninger, Josef,
Walter, Roland,
Bauer, Sabrina,
Eisinger, Kristina,
Schäffler, Andreas,
Dorn, Christoph 
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Weiss, Thomas S.,
Hellerbrand, Claus and
Buechler, Christa
(2011)
MMP-9 activity is increased by adiponectin in primary human hepatocytes but even negatively correlates with serum adiponectin in a rodent model of non-alcoholic steatohepatitis.
Experimental and Molecular Pathology 91 (2), pp. 603-607.
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Ferstl, Matthias,
Strasser, Andrea,
Wittmann, Hans-Joachim,
Drechsler, Markus,
Rischer, M.,
Engl, J. and
Goepferich, Achim
(2011)
Nanofibres Resulating from Cooperative Electrostatic and Hydrophobic Interactions between Peptides and Polyelectrolytes of Opposite Charge.
Langmuir 27, pp. 14450-14459.
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Henkel, Janin,
Gärtner, Daniela,
Dorn, Christoph 
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Hellerbrand, Claus,
Schanze, Nancy,
Elz, Sheila R. and
Püschel, Gerhard P.
(2011)
Oncostatin M produced in Kupffer cells in response to PGE2: possible contributor to hepatic insulin resistance and steatosis.
Laboratory Investigation 91 (7), pp. 1107-1117.
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Patsenker, Eleonora,
Schneider, Vreni,
Ledermann, Monika,
Saegesser, Hans,
Dorn, Christoph 
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Hellerbrand, Claus and
Stickel, Felix
(2011)
Potent antifibrotic activity of mTOR inhibitors sirolimus and everolimus but not of cyclosporine A and tacrolimus in experimental liver fibrosis.
Journal of Hepatology 55 (2), pp. 388-398.
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Bauer, Sabrina,
Wanninger, Josef,
Schmidhofer, Sandra,
Weigert, Johanna,
Neumeier, Markus,
Dorn, Christoph 
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Hellerbrand, Claus,
Zimara, Nicole,
Schäffler, Andreas,
Aslanidis, Charalampos and
Buechler, Christa
(2011)
Sterol Regulatory Element-Binding Protein 2 (SREBP2) Activation after Excess Triglyceride Storage Induces Chemerin in Hypertrophic Adipocytes.
Endocrinology 152 (1), pp. 26-35.
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Schaedlich, A.,
Caysa, H.,
Mueller, T.,
Tenambergen, F.,
Rose, Cornelia,
Goepferich, Achim,
Kuntsche, J. and
Maeder, K.
(2011)
Tumor Accumulation of NIR Fluorescent PEG PLA Nanoparticles: Impact of Particle Size and Human Xenograft Tumor Model.
ACS Nano 5, pp. 8710-8720.
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Mathar, I.,
Vennekens, R.,
Meissner, M.,
Kees, Frieder K.,
Van der Mieren, G. and
Camacho Londono, J.
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Increased catecholamine secretion contributes to hypertension in TRPM4-deficient mice.
The Journal of Clinical Investigation 120 (9), pp. 3267-3279.
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Desch, Matthias,
Schinner, Elisabeth,
Kees, Frieder K.,
Hofmann, F.,
Seifert, Roland and
Schlossmann, Jens
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Cyclic cytidine 3´,5´-monophosphate (cCMP) signals via cGMP kinase I.
FEBS Letters 584 (18), pp. 3979-3984.
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Kirovski, Georgi,
Gäbele, Erwin,
Dorn, Christoph 
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Moleda, Lukas,
Niessen, Christoph,
Weiss, Thomas S.,
Wobser, Hella,
Schacherer, Doris,
Buechler, Christa,
Wasmuth, Hermann E. and
Hellerbrand, Claus
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Hepatic steatosis causes induction of the chemokine RANTES in the absence of significant hepatic inflammation.
International Journal of Clinical and Experimental Pathology 3 (7), pp. 675-680.
Hild, Wolfgang,
Pollinger, Klaus,
Caporale, Andrea,
Cabrele, Chiara,
Keller, Max,
Pluym, Nicola,
Buschauer, Armin 
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Rachel, Reinhard 
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Tessmar, Joerg,
Breunig, Miriam and
Goepferich, Achim 
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G protein-coupled receptors function as logic gates for nanoparticle binding and cell uptake.
Proceedings of the National Academy of Sciences USA: PNAS 107 (23), pp. 10667-10672.
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Desch, Matthias,
Sigl, K.,
Hieke, Bernhard,
Salb, Katharina,
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Bernhard, D.
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IRAG determines nitric oxide- and atrial natriuretic peptide-mediated smooth muscle relaxation.
Cardiovascular Research 86 (3), pp. 496-505.
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Dorn, Christoph 
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Kirovski, Georgi,
Saugspier, Michael,
Steib, Kathrin,
Weiss, Thomas S.,
Gäbele, Erwin,
Kristiansen, Glen,
Hartmann, Arndt and
Hellerbrand, Claus
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Expression of fatty acid synthase in nonalcoholic fatty liver disease.
International Journal of Clinical and Experimental Pathology 3 (5), pp. 505-514.
Dietl, Katrin,
Renner, Kathrin,
Dettmer, Katja,
Timischl, Birgit,
Eberhart, Karin,
Dorn, Christoph 
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Hellerbrand, Claus,
Kastenberger, Michael,
Kunz-Schughart, Leoni A.,
Oefner, Peter J.,
Andreesen, Reinhard,
Gottfried, Eva and
Kreutz, Marina
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Lactic acid and acidification inhibit TNF secretion and glycolysis of human monocytes.
Journal of immunology 184 (3), pp. 1200-1209.
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Brandl, Ferdinand,
Kastner, Fritz,
Gschwind, R. M.,
Blunk, Torsten,
Teßmar, Jörg and
Göpferich, Achim
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Hydrogel-based drug delivery systems: Comparison of drug diffusivity and release kinetics.
Journal of Controlled Release 142 (2), pp. 221-228.
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Holzhauser, C.,
Berndl, Sina,
Menacher, Florian,
Breunig, Miriam,
Göpferich, Achim and
Wagenknecht, Hans-Achim
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Synthesis and Optical Properties of Cyanine Dyes as Fluorescent DNA Base Substitutions for Live Cell Imaging.
European Journal of Organic Chemistry (7), pp. 1239-1248.
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Dorn, Christoph 
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Kraus, Birgit,
Motyl, Magdalena,
Weiss, Thomas S.,
Gehrig, Manfred,
Schoelmerich, Juergen,
Heilmann, Jörg and
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Xanthohumol, a chalcon derived from hops, inhibits hepatic inflammation and fibrosis.
Molecular nutrition & food research 54 (Suppl.), S205-S213.
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Dorn, Christoph 
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Xanthohumol, a prenylated chalcone derived from hops, inhibits proliferation, migration and interleukin-8 expression of hepatocellular carcinoma cells.
International journal of oncology 36 (2), pp. 435-441.
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Arndt, Stephanie,
Mägdefrau, Ulrike,
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Iron-Induced Expression of Bone Morphogenic Protein 6 in Intestinal Cells Is the Main Regulator of Hepatic Hepcidin Expression In Vivo.
Gastroenterology 138 (1), pp. 372-382.
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Weiser, Barbara,
Sommer, Florian,
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Teßmar, Jörg,
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Ascorbic Acid Enhances Adipogenesis of Bone Marrow-Derived Mesenchymal Stromal Cells.
Cells Tissues Organs 189 (6), pp. 373-381.
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Beule, A. G.,
Steinmeier, E.,
Kaftan, H.,
Biebler, K.-E.,
Göpferich, Achim,
Wolf, Eva and
Hosemann, W.
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Effects of a dexamethasone-releasing stent on osteoneogenesis in a rabbit model.
American journal of rhinology & allergy 23 (4), pp. 433-436.
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Sommer, Florian,
Brandl, Ferdinand,
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Teßmar, Jörg,
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FACS as useful tool to study distinct hyalocyte populations.
Experimental Eye Research 88 (5), pp. 995-999.
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Elbakry, Asmaa,
Zaky, A.,
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Rachel, Reinhard,
Göpferich, Achim and
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Layer-by-Layer Assembled Gold Nanoparticles for siRNA Delivery.
Nano Letters 9 (5), pp. 2059-2064.
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Wobser, Hella,
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Lipid accumulation in hepatocytes induces fibrogenic activation of hepatic stellate cells.
Cell Research 19 (8), pp. 996-1005.
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Appel, Bernhard,
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Englert, Carsten and
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Synergistic effects of growth and differentiation factor-5 (GDF-5) and insulin on expanded chondrocytes in a 3-D environment.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 17 (11), pp. 1503-1512.
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Koelwel, C.,
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Alginate inserts loaded with epidermal growth factor for the treatment of keratoconjunctivitis sicca.
Pharmaceutical Development and Technology 13 (3), pp. 221-231.
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Beule, A. G.,
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Effects of Topically Applied Dexamethasone on Mucosal Wound Healing Using a Drug-Releasing Stent.
The Laryngoscope 118 (11), pp. 2073-2077.
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Hyalocyte proliferation and ECM accumulation modulated by bFGF and TGF-β1.
Graefe's Archive for Clinical and Experimental Ophthalmology 246 (9), pp. 1275-1284.
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Teßmar, Jörg,
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In Vivo Development and Long-Term Survival of Engineered Adipose Tissue Depend on In Vitro Precultivation Strategy.
Tissue Engineering Part A 14 (2), pp. 275-284.
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Breunig, Miriam,
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Mechanistic investigation of poly(ethylene imine)-based siRNA delivery: Disulfide bonds boost intracellular release of the cargo.
Journal of Controlled Release 130 (1), pp. 57-63.
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Role of TLR9 in hepatic stellate cells and experimental liver fibrosis.
Biochemical and Biophysical Research Communications 376 (2), pp. 271-276.
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Point Mutations in the Second Extracellular Loop of the Histamine H2 Receptor do not affect the Species-Selective Activity of Guanidine-Type Agonists.
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Sörgel, F.,
Kees, Frieder K.,
Jaehde, U. and
Schumacher, H.
(1989)
Pharmacokinetics of ciprofloxacin in young (healthy volunteers) and elderly patients, and concentrations in prostatic fluid, seminal fluid, and prostatic adenoma tissue following intravenous administration.
The American journal of medicine 87 (5supl1), S57-S59.
Naber, K. G.,
Sörgel, F.,
Kees, Frieder K.,
Schumacher, H.,
Metz, R. and
Grobecker, H.
(1988)
In-vitro activity of fleroxacin against isolates causing complicated urinary tract infections and concentrations in seminal and prostatic fluid and in prostatic adenoma tissue.
The Journal of antimicrobial chemotherapy 22 Suppl D, pp. 199-207.
Seifert, Roland,
Rosenthal, W.,
Schultz, Günter,
Wieland, T.,
Gierschick, P. and
Jakobs, K. H.
(1988)
The role of nucleoside-diphosphate kinase reactions in G protein activation of NADPH oxidase by guanine and adenine nucleotides.
European journal of biochemistry / FEBS 175 (1), pp. 51-55.
Naber, K.,
Kees, Frieder K.,
Denk, K.,
Bauernfeind, A. and
Grobecker, H.
(1987)
Carumonam versus ceftazidime: in vitro activity, pharmacokinetics in elderly patients, safety and therapeutic efficacy in the treatment of complicated urinary tract infections.
Chemioterapia 6 (2 Supl), pp. 517-518.
Fulltext not available.
Grobecker, H.,
Kees, Frieder K.,
Linden, M.,
Schrader, E. and
Welte, S.
(1987)
Untersuchungen zur Bioverfügbarkeit von Midodrin und 2,5- Dimethoxyphenyl-ß-aminoethanol-hydrochlorid [The bioavailability of midodrin and alpha-2,5-dimethoxyphenyl-beta-aminoethanol hydrochloride].
Arzneimittel-Forschung 37 (4), pp. 447-450.
Naber, K. G.,
Dette, G. A.,
Kees, Frieder K.,
Knothe, H. and
Grobecker, H.
(1986)
Pharmacokinetics, in-vitro activity, therapeutic efficacy and clinical safety of aztreonam vs. cefotaxime in the treatment of complicated urinary tract infections.
The Journal of antimicrobial chemotherapy 17 (4), pp. 517-527.
Grobecker, H.,
Gessler, I.,
Delius, W.,
Dominiak, P. and
Kees, Frieder K.
(1985)
Effect of ketanserin on hemodynamics, plasma-catecholamine concentrations, and serotonin uptake by platelets in volunteers and patients with congestive heart failure.
Journal of cardiovascular pharmacology 7, Suppl 7, S102-S104.
Kees, Frieder K.,
Naber, K. G.,
Bartoschik-Wich, B.,
Stockmann, P.,
Meyer, G. P. and
Grobecker, H.
(1985)
High-performance liquid chromatography analysis of mezlocillin, piperacillin, their degradation products, and of ioxitalamic acid in plasma and urine of healthy volunteers.
Arzneimittel-Forschung 35 (7), pp. 1099-1104.
Kees, Frieder K.,
Strehl, E.,
Dominiak, P.,
Grobecker, H.,
Seeger, K.,
Seidel, G.,
Neuhaus, B. and
Safrany, L.
(1983)
Cefotaxime and desacetyl cefotaxime in human bile.
Infection 11 (2), pp. 118-120.
Kees, Frieder K.,
Strehl, E.,
Seeger, K.,
Seidel, G.,
Dominiak, P. and
Grobecker, H.
(1981)
Comparative determination of cefotaxime and desacetyl cefotaxime in serum and bile by bioassay and high-performance liquid chromatography.
Arzneimittel-Forschung 31 (2), pp. 362-365.
This list was generated on Tue Oct 3 23:37:18 2023 CEST.