Anzahl der Einträge in dieser Kategorie: 1130.
Dejaco, Alexander ,
Dorn, Christoph ,
Lier, Constantin,
Fleischmann, Daniel,
Kratzer, Alexander,
Habler, Katharina,
Paal, Michael,
Gruber, Michael ,
Rosenberger, Johanna und
Kees, Martin G.
(2024)
Target-controlled dialysis for antibiotics (TCD-ABx).
Intensive Care Medicine Experimental 12, S. 108.
Witowski, Andrea,
Palmowski, Lars,
Minichmayr, Iris K.,
Zeitlinger, Markus,
Dorn, Christoph ,
Lier, Constantin,
Adamzik, Michael,
Nowak, Hartmuth und
Rahmel, Tim
(2024)
Concentrations of ceftazidime and avibactam in bile fluid—a prospective phase IIb study.
Journal of Antimicrobial Chemotherapy 79 (12), S. 3297-3302.
Volltext nicht vorhanden.
Sanz-Codina, Maria,
van Os, Wisse,
Pham, Anh Duc,
Jorda, Anselm,
Wölf-Duchek, Michael,
Bergmann, Felix,
Lackner, Edith,
Lier, Constantin,
Coen van Hasselt, J. G.,
Minichmayr, Iris K.,
Dorn, Christoph ,
Zeitlinger, Markus und
al Jalali, Valentin
(2024)
Target-site cefiderocol pharmacokinetics in soft tissues of healthy volunteers.
Journal of Antimicrobial Chemotherapy 79 (12), S. 3281-3288.
Unterholzner, Anna,
Kuck, Katrin,
Weinzierl, Anna,
Lipowicz, Bartosz und
Heilmann, Jörg
(2024)
An Unprecedented 4,8-Cycloeudesmane, Further New Sesquiterpenoids, a Triterpene, Steroids, and a Lignan from the Resin of Commiphora myrrha and Their Anti-Inflammatory Activity In Vitro.
Molecules 29 (18), S. 4315.
Schorr, Kathrin,
Chen, Xinyu,
Sasaki, Takanori,
Arias-Loza, Anahi Paula,
Lang, Johannes,
Higuchi, Takahiro und
Goepferich, Achim
(2024)
Rethinking Thin-Layer Chromatography for Screening Technetium-99m Radiolabeled Polymer Nanoparticles.
ACS Pharmacology & Translational Science 7 (9), S. 2604-2611.
Schatz, Lea Marie,
Greppmair, Sebastian,
Kunzelmann, Alexandra K.,
Starp, Johannes,
Brinkmann, Alexander,
Roehr, Anka,
Frey, Otto,
Hagel, Stefan,
Dorn, Christoph ,
Zoller, Michael,
Scharf, Christina,
Wicha, Sebastian G. und
Liebchen, Uwe
(2024)
Predictive performance of multi-model approaches for model-informed precision dosing of piperacillin in critically ill patients.
International Journal of Antimicrobial Agents 64 (4), S. 107305.
Brummer, Christina,
Singer, Katrin,
Brand, Almut,
Bruss, Christina,
Renner, Kathrin,
Herr, Wolfgang,
Pukrop, Tobias,
Dorn, Christoph ,
Hellerbrand, Claus,
Matos, Carina und
Kreutz, Marina
(2024)
Sex-Dependent T Cell Dysregulation in Mice with Diet-Induced Obesity.
International Journal of Molecular Sciences 25 (15), S. 8234.
Lier, Constantin,
Dejaco, Alexander ,
Kratzer, Alexander,
Kees, Martin G. ,
Kees, Frieder und
Dorn, Christoph
(2024)
Free serum concentrations of antibiotics determined by ultrafiltration: extensive evaluation of experimental variables.
Bioanalysis, S. 1-10.
Volltext nicht vorhanden.
Scheuerer, Simon,
Motlova, Lucia,
Schäker-Hübner, Linda,
Sellmer, Andreas,
Feller, Felix,
Ertl, Fabian J.,
Koch, Pierre ,
Hansen, Finn K.,
Barinka, Cyril und
Mahboobi, Siavosh
(2024)
Biological and structural investigation of tetrahydro-β-carboline-based selective HDAC6 inhibitors with improved stability.
European Journal of Medicinal Chemistry 276, S. 116676.
Mietzner, Raphael ,
Barbey, Clara,
Lehr, Heike,
Ziegler, Christian E.,
Peterhoff, David ,
Wagner, Ralf ,
Goepferich, Achim und
Breunig, Miriam
(2024)
Prolonged delivery of HIV-1 vaccine nanoparticles from hydrogels.
International Journal of Pharmaceutics 657, S. 124131.
Hosmann, Arthur,
Moser, Miriam M,
van Os, Wisse,
Gramms, Leon,
al Jalali, Valentin,
Sanz Codina, Maria,
Plöchl, Walter,
Lier, Constantin,
Kees, Frieder ,
Dorn, Christoph ,
Rössler, Karl,
Reinprecht, Andrea und
Zeitlinger, Markus
(2024)
Linezolid brain penetration in neurointensive care patients.
Journal of Antimicrobial Chemotherapy, dkae025.
Dejaco, Alexander ,
Dorn, Christoph ,
Paal, Michael,
Gruber, Michael ,
Graf, Bernhard M. und
Kees, Martin G.
(2024)
Determination of glomerular filtration rate “en passant” after high doses of iohexol for computed tomography in intensive care medicine—a proof of concept.
Frontiers in Pharmacology 15.
Haase, André,
Miroschnikov, Natalia,
Klein, Stefan,
Doege, Annika,
Dünker, Nicole,
Van Meenen, Dario,
Junker, Andreas,
Göpferich, Achim ,
Apaolaza, P. S. und
Busch, Maike Anna
(2024)
New retinoblastoma (RB) drug delivery approaches: anti-tumor effect of atrial natriuretic peptide (ANP)-conjugated hyaluronic-acid-coated gold nanoparticles for intraocular treatment of chemoresistant RB.
Molecular Oncology 18 (4), S. 832-849.
Volltext nicht vorhanden.
Wulkersdorfer, Beatrix,
Bergmann, Felix,
Amann, Lisa,
Fochtmann-Frana, Alexandra,
Al Jalali, Valentin,
Kurdina, Elizaveta,
Lackner, Edith,
Wicha, Sebastian G,
Dorn, Christoph ,
Schäfer, Bruno,
Ihra, Gerald,
Rath, Thomas,
Radtke, Christine und
Zeitlinger, Markus
(2023)
Effect of albumin substitution on pharmacokinetics of piperacillin/tazobactam in patients with severe burn injury admitted to the ICU.
Journal of Antimicrobial Chemotherapy.
Nagl, Martin,
Moennich, Denise,
Rosier, Niklas ,
Schihada, Hannes,
Sirbu, Alexei,
Konar, Nergis,
Reyes-Resina, Irene,
Navarro, Gemma,
Franco, Rafael,
Kolb, Peter,
Annibale, Paolo und
Pockes, Steffen
(2023)
Fluorescent Tools for the Imaging of Dopamine D2‐Like Receptors.
ChemBioChem.
Rosier, Niklas ,
Moennich, Denise,
Nagl, Martin,
Schihada, Hannes,
Sirbu, Alexei,
Konar, Nergis,
Reyes-Resina, Irene,
Navarro, Gemma,
Franco, Rafael,
Kolb, Peter,
Annibale, Paolo und
Pockes, Steffen
(2023)
Shedding Light on the D1‐Like Receptors: A Fluorescence‐Based Toolbox for Visualization of the D1 and D5 Receptors.
ChemBioChem.
Greppmair, Sebastian,
Brinkmann, Alexander,
Roehr, Anka,
Frey, Otto,
Hagel, Stefan,
Dorn, Christoph ,
Marsot, Amélie,
El-Haffaf, Ibrahim,
Zoller, Michael,
Saller, Thomas,
Zander, Johannes,
Schatz, Lea Marie,
Scharf, Christina,
Briegel, Josef,
Minichmayr, Iris K.,
Wicha, Sebastian G. und
Liebchen, Uwe
(2023)
Towards model-informed precision dosing of piperacillin: multicenter systematic external evaluation of pharmacokinetic models in critically ill adults with a focus on Bayesian forecasting.
Intensive Care Medicine.
Chen, Zhendong,
Taubert, Max,
Chen, Chunli,
Dokos, Charalambos,
Fuhr, Uwe,
Weig, Thomas,
Zoller, Michael,
Heck, Suzette,
Dimitriadis, Konstantinos,
Terpolilli, Nicole,
Kinast, Christina,
Scharf, Christina,
Lier, Constantin,
Dorn, Christoph und
Liebchen, Uwe
(2023)
Plasma and Cerebrospinal Fluid Population Pharmacokinetics of Vancomycin in Patients with External Ventricular Drain.
Antimicrobial Agents and Chemotherapy.
Volltext nicht vorhanden.
Wirth, Ulrike,
Erl, Julia,
Azzam, Saphia,
Hoering, Carina,
Skiba, Michael,
Singh, Ritu,
Hochmuth, Kathrin,
Keller, Max ,
Wegener, Joachim und
König, Burkhard
(2023)
Monitoring the Reversibility of GPCR Signaling by Combining Photochromic Ligands with Label-free Impedance Analysis.
Angewandte Chemie International Edition, e202215547.
Sanz-Codina, Maria,
Wicha, Sebastian G,
Wulkersdorfer, Beatrix,
Al Jalali, Valentin,
Van Os, Wisse,
Vossen, Matthias G,
Bauer, Martin,
Lackner, Edith,
Dorn, Christoph und
Zeitlinger, Markus
(2022)
Comparison of ultrafiltration and microdialysis for ceftriaxone protein-binding determination.
Journal of Antimicrobial Chemotherapy.
Volltext nicht vorhanden.
Jorda, Anselm ,
Wulkersdorfer, Beatrix,
Schoergenhofer, Christian,
Matzneller, Peter,
Jalali, Valentin A. L.,
Bauer, Martin,
Wölfl‐Duchek, Michael,
Lackner, Edith,
Dorn, Christoph ,
Jilma, Bernd und
Zeitlinger, Markus
(2022)
Effect of the human endotoxin challenge on tedizolid tissue penetration.
British Journal of Clinical Pharmacology, (accept.art.).
Volltext nicht vorhanden.
Schindler, Lisa,
Moosbauer, Jutta,
Schmidt, Daniel ,
Spruss, Thilo,
Grätz, Lukas,
Lüdeke, Steffen,
Hofheinz, Frank,
Meister, Sebastian,
Echtenacher, Bernd,
Bernhardt, Günther,
Pietzsch, Jens ,
Hellwig, Dirk und
Keller, Max
(2022)
Development of a Neurotensin-Derived 68Ga-Labeled PET Ligand with High In Vivo Stability for Imaging of NTS1 Receptor-Expressing Tumors.
Cancers 14 (19), S. 4922.
Bohley, Marilena,
Dillinger, Andrea E.,
Schweda, Frank,
Ohlmann, Andreas,
Braunger, Barbara M.,
Tamm, Ernst R. und
Goepferich, Achim
(2022)
A single intravenous injection of cyclosporin A–loaded lipid nanocapsules prevents retinopathy of prematurity.
Science Advances 8 (38).
Heinl, Elena-Sofia,
Lorenz, Sebastian,
Schmidt, Barbara ,
Laqtom, Nouf Nasser M.,
Mazzulli, Joseph R.,
Francelle, Laetitia ,
Yu, Timothy W.,
Greenberg, Benjamin ,
Storch, Stephan,
Tegtmeier, Ines,
Othmen, Helga,
Maurer, Katja,
Steinfurth, Malin,
Witzgall, Ralph,
Milenkovic, Vladimir M.,
Wetzel, Christian H. und
Reichold, Markus
(2022)
CLN7/MFSD8 may be an important factor for SARS-CoV-2 cell entry.
iScience 25 (10), S. 105082.
Dorn, Christoph ,
Petroff, David,
Kratzer, Alexander,
Kees, Frieder,
Kloft, Charlotte,
Zeitlinger, Markus ,
Wrigge, Hermann und
Simon, Philipp
(2022)
Tigecycline Soft Tissue Penetration in Obese and Non-obese Surgical Patients Determined by Using In Vivo Microdialysis.
European Journal of Drug Metabolism and Pharmacokinetics 47, S. 749-755.
Meurer, Florian ,
Dolomanov, Oleg V.,
Hennig, Christoph ,
Peyerimhoff, Norbert ,
Kleemiss, Florian ,
Puschmann, Horst und
Bodensteiner, Michael
(2022)
Refinement of anomalous dispersion correction parameters in single-crystal structure determinations.
IUCrJ / International Union of Crystallography 9 (5), S. 604-609.
Willkomm, Sarah ,
Jakob, Leonhard,
Kramm, Kevin,
Graus, Veronika,
Neumeier, Julia,
Meister, Gunter und
Grohmann, Dina
(2022)
Single-molecule FRET uncovers hidden conformations and dynamics of human Argonaute 2.
Nature Communications 13, art.no.3825.
Bresinsky, Merlin,
Strasser, Jessica M.,
Hubmann, Alexander,
Vallaster, Bernadette,
McCue, William M.,
Fuller, Jessica,
Singh, Gurpreet,
Nelson, Kathryn M.,
Cuellar, Matthew E.,
Finzel, Barry C.,
Ashe, Karen H.,
Walters, Michael A. und
Pockes, Steffen
(2022)
Characterization of caspase‐2 inhibitors based on specific sites of caspase‐2‐mediated proteolysis.
Archiv der Pharmazie 355 (9), S. 2200095.
Jorda, Anselm ,
Wulkersdorfer, Beatrix,
Schörgenhofer, Christian,
Matzneller, Peter ,
Al Jalali, Valentin,
Bauer, Martin ,
Wölf-Duchek, Michael,
Lackner, Edith,
Dorn, Christoph,
Jilma, Bernd und
Zeitlinger, Markus
(2022)
Influence of tedizolid on the cytokine response to the endotoxin challenge in healthy volunteers: a cross-over trial.
Journal of Antimicrobial Chemotherapy.
Volltext nicht vorhanden.
Ousingsawat, Jiraporn ,
Centeio, Raquel,
Cabrita, Inês ,
Talbi, Khaoula,
Zimmer, Oliver ,
Graf, Moritz,
Göpferich, Achim ,
Schreiber, Rainer und
Kunzelmann, Karl
(2022)
Airway Delivery of Hydrogel-Encapsulated Niclosamide for the Treatment of Inflammatory Airway Disease.
International Journal of Molecular Sciences 23 (3), S. 1085.
Rösch, Gundula,
Muschter, Dominique,
Taheri, Shahed ,
El Bagdadi, Karima,
Dorn, Christoph,
Meurer, Andrea,
Zaucke, Frank,
Schilling, Arndt F.,
Grässel, Susanne,
Straub, Rainer H. und
Jenei-Lanzl, Zsuzsa
(2022)
β2-Adrenoceptor Deficiency Results in Increased Calcified Cartilage Thickness and Subchondral Bone Remodeling in Murine Experimental Osteoarthritis.
Frontiers in Immunology 12.
Tahk, Maris-Johanna ,
Torp, Jane ,
Ali, Mohammed A. S. ,
Fishman, Dmytro,
Parts, Leopold ,
Grätz, Lukas ,
Müller, Christoph ,
Keller, Max ,
Veiksina, Santa ,
Laasfeld, Tõnis und
Rinken, Ago
(2022)
Live-cell microscopy or fluorescence anisotropy with budded baculoviruses—which way to go with measuring ligand binding to M 4 muscarinic receptors?
Open Biology 12 (6).
Volltext nicht vorhanden.
Barda, Christina,
Anastasiou, Konstantina,
Tzara, Ariadni,
Grafakou, Maria-Eleni,
Kalpoutzakis, Eleftherios,
Heilmann, Joerg,
Rallis, Michael,
Kourounakis, Angeliki P. und
Skaltsa, Helen
(2022)
A Bio-Guided Screening for Antioxidant, Anti-Inflammatory and Hypolipidemic Potential Supported by Non-Targeted Metabolomic Analysis of Crepis spp.
Molecules 27 (19), S. 6173.
Volltext nicht vorhanden.
Andreev, Stanislav,
Pantsar, Tatu,
Tesch, Roberta,
Kahlke, Niclas,
El-Gokha, Ahmed,
Ansideri, Francesco,
Grätz, Lukas,
Romasco, Jenny,
Sita, Giulia,
Geibel, Christian ,
Lämmerhofer, Michael,
Tarozzi, Andrea,
Knapp, Stefan ,
Laufer, Stefan A. und
Koch, Pierre
(2022)
Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors.
Journal of Medicinal Chemistry 65 (2), S. 1283-1301.
Volltext nicht vorhanden.
Mandigma, Mark John P. ,
Žurauskas, Jonas,
MacGregor, Callum I.,
Edwards, Lee J. ,
Shahin, Ahmed ,
d'Heureuse, Ludwig,
Yip, Philip,
Birch, David J. S. ,
Gruber, Thomas,
Heilmann, Jörg,
John, Matthew P. und
Barham, Joshua P.
(2022)
An organophotocatalytic late-stage N–CH3oxidation of trialkylamines toN-formamides with O2in continuous flow.
Chemical Science 13 (7), S. 1912-1924.
Volltext nicht vorhanden.
Katsouri, Ilektra Petrina,
Vandervelpen, Ebert Vinciane G.,
Gattor, Albert Owusu,
Engelbeen, Sarah,
El Sayed, Abdulrahman,
Seitaj, Klejdia,
Becerra, Eduardo Daniel Morales und
Vanderheyden, Patrick M.L.
(2022)
Complex FFA1 receptor (in)dependent modulation of calcium signaling by free fatty acids.
Biochemical Pharmacology 202, S. 115150.
Volltext nicht vorhanden.
Schoretsanitis, Georgios,
Haen, Ekkehard,
Piacentino, Daria,
Conca, Andreas,
Endres, Katharina,
Hiemke, Christoph,
Gründer, Gerhard und
Paulzen, Michael
(2022)
Effects of body weight, smoking status, and sex on plasma concentrations of once-monthly paliperidone palmitate.
Expert Review of Clinical Pharmacology 15 (2), S. 243-249.
Volltext nicht vorhanden.
Beyer, Mandy,
Henninger, Sven J.,
Haehnel, Patricia S.,
Mustafa, Al-Hassan M. ,
Gurdal, Ece ,
Schubert, Bastian,
Christmann, Markus,
Sellmer, Andreas ,
Mahboobi, Siavosh,
Drube, Sebastian,
Sippl, Wolfgang,
Kindler, Thomas und
Krämer, Oliver H.
(2022)
Identification of a highly efficient dual type I/II FMS-like tyrosine kinase inhibitor that disrupts the growth of leukemic cells.
Cell Chemical Biology 29 (3), 398-411.e4.
Volltext nicht vorhanden.
Schihada, Hannes,
Klompstra, Thomas M. ,
Humphrys, Laura J. ,
Cervenka, Igor,
Dadvar, Shamim ,
Kolb, Peter ,
Ruas, Jorge L. und
Schulte, Gunnar
(2022)
Isoforms of GPR35 have distinct extracellular N-termini that allosterically modify receptor-transducer coupling and mediate intracellular pathway bias.
Journal of Biological Chemistry 298 (9), S. 102328.
Volltext nicht vorhanden.
Peterhoff, David ,
Thalhauser, Stefanie,
Neckermann, Patrick ,
Barbey, Clara,
Straub, Kristina,
Nazet, Julian,
Merkl, Rainer,
Längst, Gernot,
Breunig, Miriam und
Wagner, Ralf
(2022)
Multivalent display of engineered HIV-1 envelope trimers on silica nanoparticles for targeting and in vitro activation of germline VRC01 B cells.
European Journal of Pharmaceutics and Biopharmaceutics 181, S. 88-101.
Volltext nicht vorhanden.
Schindler, Lisa,
Wohlfahrt, Katrin,
Gluhacevic von Krüchten, Lara,
Prante, Olaf,
Keller, Max und
Maschauer, Simone
(2022)
Neurotensin analogs by fluoroglycosylation at Nω-carbamoylated arginines for PET imaging of NTS1-positive tumors.
Scientific Reports 12 (1).
Volltext nicht vorhanden.
Greinwald, Anja,
Hartmann, Martin,
Heilmann, Jörg,
Heinrich, Michael,
Luick, Rainer und
Reif, Albert
(2022)
Soil and Vegetation Drive Sesquiterpene Lactone Content and Profile in Arnica montana L. Flower Heads From Apuseni-Mountains, Romania.
Frontiers in Plant Science 13.
Volltext nicht vorhanden.
Szczepańska, Katarzyna,
Podlewska, Sabina,
Dichiara, Maria,
Gentile, Davide,
Patamia, Vincenzo,
Rosier, Niklas,
Mönnich, Denise,
Ruiz Cantero, Ma Carmen,
Karcz, Tadeusz,
Łażewska, Dorota,
Siwek, Agata,
Pockes, Steffen,
Cobos, Enrique J.,
Marrazzo, Agostino,
Stark, Holger,
Rescifina, Antonio,
Bojarski, Andrzej J.,
Amata, Emanuele und
Kieć-Kononowicz, Katarzyna
(2022)
Structural and Molecular Insight into Piperazine and Piperidine Derivatives as Histamine H3 and Sigma-1 Receptor Antagonists with Promising Antinociceptive Properties.
ACS Chemical Neuroscience 13 (1), S. 1-15.
Volltext nicht vorhanden.
Müller, Christoph,
Gleixner, Jakob ,
Tahk, Maris-Johanna ,
Kopanchuk, Sergei ,
Laasfeld, Tõnis,
Weinhart, Michael,
Schollmeyer, Dieter,
Betschart, Martin U.,
Lüdeke, Steffen,
Koch, Pierre,
Rinken, Ago und
Keller, Max
(2022)
Structure-Based Design of High-Affinity Fluorescent Probes for the Neuropeptide Y Y1 Receptor.
Journal of Medicinal Chemistry 65 (6), S. 4832-4853.
Volltext nicht vorhanden.
Rösch, G.,
El Bagdadi, K.,
Muschter, D.,
Taheri, S. ,
Dorn, C.,
Meurer, A.,
Straub, R.H.,
Zaucke, F. ,
Schilling, A.F.,
Grässel, S. und
Jenei-Lanzl, Z.
(2022)
Sympathectomy aggravates subchondral bone changes during osteoarthritis progression in mice without affecting cartilage degeneration or synovial inflammation.
Osteoarthritis and Cartilage 30 (3), S. 461-474.
Volltext nicht vorhanden.
Mietzner, Raphael ,
Pawlak, Ramona ,
Tamm, Ernst R.,
Goepferich, Achim ,
Fuchshofer, Rudolf und
Breunig, Miriam
(2021)
Angiopoietin-1 Mimetic Nanoparticles for Restoring the Function of Endothelial Cells as Potential Therapeutic for Glaucoma.
Pharmaceuticals 15 (1), S. 18.
Busse, David,
Simon, Philipp,
Schmitt, Lisa,
Petroff, David,
Dorn, Christoph ,
Dietrich, Arne,
Zeitlinger, Markus,
Huisinga, Wilhelm,
Michelet, Robin,
Wrigge, Hermann und
Kloft, Charlotte
(2021)
Comparative Plasma and Interstitial Tissue Fluid Pharmacokinetics of Meropenem Demonstrate the Need for Increasing Dose and Infusion Duration in Obese and Non-obese Patients.
Clinical Pharmacokinetics.
Dorn, Christoph
(2021)
3.3. Informationen über Arzneimittel.
In:
Sax, Michael, (ed.)
Pharmazie für die Praxis : Lehrbuch für Pharmazeuten im Praktikum : Handbuch für die Apotheke.
Deutscher Apotheker Verlag, Stuttgart, S. 152-173.
ISBN 978-3-7692-7010-5.
Volltext nicht vorhanden.
Rösch, Gundula,
El Bagdadi, Karima,
Muschter, Dominique ,
Taheri, Shahed,
Dorn, Christoph ,
Meurer, Andrea,
Straub, Rainer H. ,
Zaucke, Frank ,
Schilling, Arndt F.,
Grässel, Susanne und
Jenei-Lanzl, Zsuzsa
(2021)
Sympathectomy aggravates subchondral bone changes during osteoarthritis progression in mice without affecting cartilage degeneration or synovial inflammation.
Osteoarthritis and Cartilage 30 (3), S. 461-474.
Volltext nicht vorhanden.
Wachholz, Vanessa,
Mustafa, Al-Hassan M.,
Zeyn, Yanira,
Henninger, Sven J.,
Beyer, Mandy,
Dzulko, Melanie,
Piée-Staffa, Andrea,
Brachetti, Christina,
Haehnel, Patricia S.,
Sellmer, Andreas,
Mahboobi, Siavosh,
Kindler, Thomas,
Brenner, Walburgis,
Nikolova, Teodora und
Krämer, Oliver H.
(2021)
Inhibitors of class I HDACs and of FLT3 combine synergistically against leukemia cells with mutant FLT3.
Archives of Toxicology 96 (1), S. 177-193.
Busse, David,
Borghardt, Jens Markus,
Petroff, David,
Pevzner, Alice,
Dorn, Christoph ,
El‐Najjar, Nahed,
Huisinga, Wilhelm,
Wrigge, Hermann,
Simon, Philipp und
Kloft, Charlotte
(2021)
EVALUATING PREDICTION METHODS FOR GLOMERULAR FILTRATION TO OPTIMISE DRUG DOSES IN OBESE AND NON‐OBESE PATIENTS.
British Journal of Clinical Pharmacology.
Volltext nicht vorhanden.
Höring, Carina ,
Conrad, Marcus,
Söldner, Christian A. ,
Wang, Jinan ,
Sticht, Heinrich ,
Strasser, Andrea und
Miao, Yinglong
(2021)
Specific Engineered G Protein Coupling to Histamine Receptors Revealed from Cellular Assay Experiments and Accelerated Molecular Dynamics Simulations.
International Journal of Molecular Sciences 22 (18), S. 1-21.
Busse, David ,
Simon, Philipp ,
Petroff, David,
Dorn, Christoph,
Schmitt, Lisa,
Bindellini, Davide,
Kratzer, Alexander,
Dietrich, Arne,
Zeitlinger, Markus,
Huisinga, Wilhelm ,
Michelet, Robin ,
Wrigge, Hermann und
Kloft, Charlotte
(2021)
Similar Piperacillin/Tazobactam Target Attainment in Obese versus Nonobese Patients despite Differences in Interstitial Tissue Fluid Pharmacokinetics.
Pharmaceutics 13 (9), S. 1380.
Breunig, Miriam,
Sonntag, Tobias,
Froemel, Franziska,
Stamer, W. Daniel,
Ohlmann, Andreas und
Fuchshofer, Rudolf
(2021)
Distribution of Gold Nanoparticles in the Anterior Chamber of the Eye after Intracameral Injection for Glaucoma Therapy.
Pharmaceutics 2021 (13), S. 901.
(Eingereicht)
Peterhoff, David ,
Thalhauser, Stefanie,
Sobczak, Jan M.,
Mohsen, Mona O.,
Voigt, Christoph,
Seifert, Nicole ,
Neckermann, Patrick,
Hauser, Alexandra ,
Ding, Song,
Sattentau, Quentin,
Bachmann, Martin F. ,
Breunig, Miriam und
Wagner, Ralf
(2021)
Augmenting the Immune Response against a Stabilized HIV-1 Clade C Envelope Trimer by Silica Nanoparticle Delivery.
Vaccines 9 (642), S. 1-24.
Schießer, Selina,
Hitzenbichler, Florian,
Kees, Martin Georg,
Kratzer, Alexander,
Lubnow, Matthias ,
Salzberger, Bernd ,
Kees, Frieder und
Dorn, Christoph
(2021)
Measurement of Free Plasma Concentrations of Beta-Lactam Antibiotics.
Therapeutic Drug Monitoring 43 (2), S. 264-270.
Volltext nicht vorhanden.
Hoffmeister, Helen,
Fuchs, Andreas ,
Komives, Elizabeth,
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Novel azulene derivatives for the treatment of erectile dysfunction.
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A library of strictly linear poly(ethylene glycol)-poly(ethylene imine) diblock coploymers to perform structure-function relationship on non-viral gene carriers.
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A novel approach to prevent endothelial hyperpermeability: The Crataegus extract WS® 1442 targets the cAMP/Rap1 pathway.
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Hop bitter acids inhibit tumorigenicity of hepatocellular carcinoma cells in vitro.
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Kidney Podocytes as Specific Targets for cyclo(RGDfC)-Modified Nanoparticles.
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Novel inhibitors of epidermal growth factor receptor: (4-(Arylamino)-7H-pyrrolo[2,3-d]pyrimidin-6-yl)(1H-indol-2-yl)methanones and (1H-indol-2-yl)(4-(phenylamino)thieno[2,3-d]pyrimidin-6-yl)methanones.
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Novel neurological and immunological targets for salicylate-based phytopharmaceuticals and for the anti-depressant imipramine.
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S.02.02 Neuropeptide S and anxiety.
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Tacrine-Silibinin Codrug Shows Neuro- and Hepatoprotective Effects in Vitro and Pro-Cognitive and Hepatoprotective Effects in Vivo.
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Targeting melanoma metastasis and immunosuppression with a new mode of melanoma inhibitory activity (MIA) protein inhibition.
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Targeting of LOX-1 by willow bark, its etoh-fraction and by the antidepressant imipramine.
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The Novel Sinupret® dry extract BNO 1011 inhibits paw oedema development in vivo and inflammatory mediator release in vitro.
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Design of benzimidazole- and benzoxazole-2-thione derivatives as inhibitors of bacterial hyaluronan lyase.
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Hübner, Melanie,
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Structural Basis for the High-Affinity Inhibition of Mammalian Membranous Adenylyl Cyclase by 2`,3`-O-(N-Methylanthraniloyl)-Inosine 5`-Triphosphate.
Molecular Pharmacology 80 (1), S. 87-96.
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Discrimination of steatosis and NASH in mice using nuclear magnetic resonance spectroscopy.
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Perioperative moxifloxacin treatment in rats subjected to deep hypothermic circulatory arrest: reduction in cerebral inflammation but without improvement in cognitive performance.
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A New Model of Interactive Effects of Alcohol and High-Fat Diet on Hepatic Fibrosis.
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Comparative analysis of gene expression profiles from rats treated with a standardized willow bark preparation, its salicin rich ethanol fraction and imipramine for toxicological endpoints.
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Comprehensive Analysis of Artemisiae scopariae herba from different growing areas.
Planta Medica 77 (12).
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Rossbach, K.,
Nassenstein, C.,
Gschwandtner, M. ,
Schnell, D.,
Sander, K.,
Seifert, R.,
Stark, H. ,
Kietzmann, M. und
Bäumer, W.
(2011)
Histamine H1, H3 and H4 receptors are involved in pruritus.
Neuroscience 190, S. 89-102.
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Schaedlich, A.,
Rose, C.,
Kuntsche, J.,
Caysa, H.,
Mueller, T.,
Goepferich, Achim und
Maeder, K.
(2011)
How Stealthy are PEG-PLA Nanoparticles? An NIR In Vivo Study Combined with Detailed Size Measurements.
Pharmaceutical Research 28 (8), S. 1995-2007.
Volltext nicht vorhanden.
Ertl, C.,
Lukowski, R.,
Sigl, K.,
Schlossmann, Jens ,
Hofmann, F. und
Wegener, Jörg W.
(2011)
Kinetics of relaxation by cGMP/cGKI signaling in fundus smooth muscle.
Eur J Pharmacol 670 (1), S. 266-271.
Volltext nicht vorhanden.
Oberprieler, Christoph,
Hartl, Sabine,
Schauer, Kerstin,
Meister, Jörg und
Heilmann, Jörg
(2011)
Morphological, phytochemical and genetic variation in mixed stands and a hybrid swarm of Senecio germanicus and S. ovatus (Compositae, Senecioneae).
Plant Systematics and Evolution 293 (1-4), S. 177-191.
Volltext nicht vorhanden.
Macabeo, Allan Patrick G.,
Vidar, Warren S.,
Chen, Xinyu,
Decker, Michael,
Heilmann, Jörg,
Wan, Baojie,
Franzblau, Scott G. ,
Galvez, Elano V.,
Aguinaldo, Ma. Alicia M. und
Cordell, Geoffrey A.
(2011)
Mycobacterium tuberculosis and cholinesterase inhibitors from Voacanga globosa.
European Journal of Medicinal Chemistry 46 (7), S. 3118-3123.
Volltext nicht vorhanden.
Ferstl, Matthias,
Strasser, Andrea,
Wittmann, Hans-Joachim,
Drechsler, Markus ,
Rischer, M.,
Engl, J. und
Goepferich, Achim
(2011)
Nanofibres Resulating from Cooperative Electrostatic and Hydrophobic Interactions between Peptides and Polyelectrolytes of Opposite Charge.
Langmuir 27, S. 14450-14459.
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Henkel, Janin,
Gärtner, Daniela,
Dorn, Christoph ,
Hellerbrand, Claus,
Schanze, Nancy,
Elz, Sheila R. und
Püschel, Gerhard P.
(2011)
Oncostatin M produced in Kupffer cells in response to PGE2: possible contributor to hepatic insulin resistance and steatosis.
Laboratory Investigation 91 (7), S. 1107-1117.
Volltext nicht vorhanden.
Posavec, Damir,
Dorsch, Andre,
Bogner, Udo,
Bernhardt, Guenther und
Nagl, Stefan
(2011)
Polyvinyl butyral nanobeads: preparation, characterization, biocompatibility and cancer cell uptake.
Microchimica acta 173 (3-4), S. 391-399.
Volltext nicht vorhanden.
Patsenker, Eleonora,
Schneider, Vreni,
Ledermann, Monika,
Saegesser, Hans,
Dorn, Christoph ,
Hellerbrand, Claus und
Stickel, Felix
(2011)
Potent antifibrotic activity of mTOR inhibitors sirolimus and everolimus but not of cyclosporine A and tacrolimus in experimental liver fibrosis.
Journal of Hepatology 55 (2), S. 388-398.
Volltext nicht vorhanden.
Ochoa Puentes, Cristian,
Höcherl, Peter,
Kühnle, Matthias,
Bauer, Stefanie,
Kürger, Kira,
Bernhardt, Günther,
Buschauer, Armin und
König, Burkhard
(2011)
Solid phase synthesis of tariquidar-related modulators of ABC transporters preferring breast cancer resistance protein (ABCG2).
Bioorganic & Medicinal Chemistry Letters 21 (12), S. 3654-3657.
Volltext nicht vorhanden.
Bauer, Sabrina,
Wanninger, Josef,
Schmidhofer, Sandra,
Weigert, Johanna,
Neumeier, Markus,
Dorn, Christoph ,
Hellerbrand, Claus,
Zimara, Nicole,
Schäffler, Andreas,
Aslanidis, Charalampos und
Buechler, Christa
(2011)
Sterol Regulatory Element-Binding Protein 2 (SREBP2) Activation after Excess Triglyceride Storage Induces Chemerin in Hypertrophic Adipocytes.
Endocrinology 152 (1), S. 26-35.
Volltext nicht vorhanden.
Werder, A.,
Mayr, M.,
Schneider, G.,
Oesterle, D.,
Fritsch, R. M.,
Seidler, B.,
Schlossmann, Jens ,
Hofmann, F.,
Schemann, M. ,
Allescher, H. D.,
Schmid, R. M. und
Saur, D.
(2011)
Truncated IRAG variants modulate cGMP-mediated inhibition of human colonic smooth muscle cell contraction.
American Journal of Physiology - Cell Physiology : Am J Physiol Cell Physiol 301 (6), C1445-1457.
Volltext nicht vorhanden.
Schaedlich, A.,
Caysa, H.,
Mueller, T.,
Tenambergen, F.,
Rose, Cornelia,
Goepferich, Achim ,
Kuntsche, J. und
Maeder, K.
(2011)
Tumor Accumulation of NIR Fluorescent PEG PLA Nanoparticles: Impact of Particle Size and Human Xenograft Tumor Model.
ACS Nano 5, S. 8710-8720.
Volltext nicht vorhanden.
Wolff, Horst,
Motyl, Magdalena,
Hellerbrand, Claus,
Heilmann, Jörg und
Kraus, Birgit
(2011)
Xanthohumol Uptake and Intracellular Kinetics in Hepatocytes, Hepatic Stellate Cells, and Intestinal Cells.
Journal of Agricultural and Food Chemistry 59 (24), S. 12893-12901.
Volltext nicht vorhanden.
Igel, Patrick,
Dove, Stefan und
Buschauer, Armin
(2010)
Histamine H4 receptor agonists.
Bioorganic & Medicinal Chemistry Letters 20 (24), S. 7191-7199.
Volltext nicht vorhanden.
Dayoub, Rania ,
Wagner, Hannah,
Bataille, Frauke,
Stöltzing, Oliver,
Spruss, Thilo,
Buechler, Christa,
Schlitt, Hans-Jürgen und
Weiss, Thomas S.
(2010)
Liver Regeneration Associated Protein (ALR) Exhibits Antimetastatic Potential in Hepatocellular Carcinoma.
Molecular Medicine 17, S. 221-228.
Modrow, Susanne,
Wenzel, J. J. ,
Schimanski, S.,
Schwarzbeck, J.,
Rothe, U.,
Oldenburg, J.,
Jilg, W. und
Eis-Hübinger, A. M.
(2010)
Prevalence of nucleic acid sequences specific for human parvoviruses, hepatitis A and hepatitis E viruses in coagulation factor concentrates.
Vox sanguinis.
Zugang zum Volltext eingeschränkt.
Mathar, I.,
Vennekens, R.,
Meissner, M.,
Kees, Frieder K.,
Van der Mieren, G. und
Camacho Londono, J.
(2010)
Increased catecholamine secretion contributes to hypertension in TRPM4-deficient mice.
The Journal of Clinical Investigation 120 (9), S. 3267-3279.
Volltext nicht vorhanden.
Desch, Matthias,
Schinner, Elisabeth,
Kees, Frieder K.,
Hofmann, F.,
Seifert, Roland und
Schlossmann, Jens
(2010)
Cyclic cytidine 3´,5´-monophosphate (cCMP) signals via cGMP kinase I.
FEBS Letters 584 (18), S. 3979-3984.
Volltext nicht vorhanden.
Kirovski, Georgi,
Gäbele, Erwin,
Dorn, Christoph ,
Moleda, Lukas,
Niessen, Christoph,
Weiss, Thomas S. ,
Wobser, Hella,
Schacherer, Doris,
Buechler, Christa ,
Wasmuth, Hermann E. und
Hellerbrand, Claus
(2010)
Hepatic steatosis causes induction of the chemokine RANTES in the absence of significant hepatic inflammation.
International Journal of Clinical and Experimental Pathology 3 (7), S. 675-680.
Desch, Matthias,
Sigl, K.,
Hieke, Bernhard,
Salb, Katharina,
Kees, F.,
Bernhard, D.,
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(2010)
IRAG determines nitric oxide- and atrial natriuretic peptide-mediated smooth muscle relaxation.
Cardiovascular Research 86 (3), S. 496-505.
Volltext nicht vorhanden.
Ghorai, Prasanta,
Kraus, Anja,
Birnkammer, Tobias,
Geyer, Roland,
Bernhardt, Günther,
Dove, Stefan,
Seifert, Roland,
Elz, Sigurd und
Buschauer, Armin
(2010)
Chiral N(G)-acylated hetarylpropylguanidine-type histamine H2 receptor agonists do not show significant stereoselectivity.
Bioorganic & Medicinal Chemistry Letters 20 (10), S. 3173-3176.
Volltext nicht vorhanden.
Dorn, Christoph ,
Riener, Marc-Oliver,
Kirovski, Georgi,
Saugspier, Michael,
Steib, Kathrin,
Weiss, Thomas S. ,
Gäbele, Erwin,
Kristiansen, Glen,
Hartmann, Arndt und
Hellerbrand, Claus
(2010)
Expression of fatty acid synthase in nonalcoholic fatty liver disease.
International Journal of Clinical and Experimental Pathology 3 (5), S. 505-514.
Amann, Thomas,
Bataille, Frauke,
Spruss, Thilo,
Dettmer, Katja ,
Wild, Peter J.,
Liedtke, Christian ,
Mühlbauer, Marcus,
Kiefer, Paul,
Oefner, Peter J. ,
Trautwein, Christian,
Bosserhoff, Anja-Katrin und
Hellerbrand, Claus
(2010)
Reduced expression of fibroblast growth factor receptor 2IIIb in hepatocellular carcinoma induces a more aggressive growth.
The American journal of pathology 176 (3), S. 1433-42.
Volltext nicht vorhanden.
Dietl, Katrin,
Renner, Kathrin,
Dettmer, Katja ,
Timischl, Birgit,
Eberhart, Karin,
Dorn, Christoph,
Hellerbrand, Claus,
Kastenberger, Michael,
Kunz-Schughart, Leoni A.,
Oefner, Peter J. ,
Andreesen, Reinhard,
Gottfried, Eva und
Kreutz, Marina
(2010)
Lactic acid and acidification inhibit TNF secretion and glycolysis of human monocytes.
Journal of immunology 184 (3), S. 1200-1209.
Volltext nicht vorhanden.
Feizlmayr, E,
Sutor, S,
Stinglmayr, I,
Kunert, O,
Heilmann, J und
Bauer, R
(2010)
Cannabinoid receptor activity of polyacetylenes and polyenes from Echinacea pallida.
Planta Medica 76 (12).
Volltext nicht vorhanden.
Uecker, Andrea,
Sicker, Marit,
Beckers, Thomas,
Mahboobi, Siavosh,
Hägerstrand, Daniel ,
Östman, Arne und
Böhmer, Frank-D.
(2010)
Chimeric tyrosine kinase-HDAC inhibitors as antiproliferative agents.
Anti-Cancer Drugs 21 (8), S. 759-765.
Volltext nicht vorhanden.
Göttle, Martin,
Dove, Stefan,
Kees, Frieder K.,
Schlossmann, Jens ,
Geduhn, Jens,
König, Burkhard ,
Shen, Y.,
Tang, W. J. ,
Kaever, V. und
Seifert, Roland
(2010)
Citidylyl and uridylyl cyclase activity of bacillus anthracis edema factor and Bordetella pertussis CyaA.
Biochemistry 49, S. 5494-5503.
Volltext nicht vorhanden.
Kleinmaier, Roland,
Igel, Patrick,
Keller, Max,
Buschauer, Armin und
Gschwind, Ruth M.
(2010)
Conformations, Conformational Preferences, and Conformational Exchange of N'-Substituted N-Acylguanidines: Intermolecular Interactions Hold the Key.
J. Am. Chem. Soc. 132 (32), S. 11223-11233.
Volltext nicht vorhanden.
Desch, Matthias,
Schinner, Elisabeth,
Kees, Frieder,
Hofmann, Franz,
Seifert, Roland und
Schlossmann, Jens
(2010)
Cyclic cytidine 3′,5′‐monophosphate (cCMP) signals via cGMP kinase I.
FEBS Letters 584 (18), S. 3979-3984.
Volltext nicht vorhanden.
Shwe, Htay Htay,
Aye, Mye,
Sein, Myint Myint,
Htay, Khin Than,
Kreitmeier, Peter,
Gertsch, Jürg,
Reiser, Oliver und
Heilmann, Jörg
(2010)
Cytotoxic Steroidal Saponins from the Rhizomes of Tacca integrifolia.
Chemistry & Biodiversity 7 (3), S. 610-622.
Volltext nicht vorhanden.
Schmidt, Florian,
Schmidt, J.,
Riechers, A.,
Haase, S.,
Bosserhoff, Anja-Katrin,
Heilmann, J. und
König, Burkhard
(2010)
DNA Staining in Agarose Gels with Zn2+ -Cyclen-Pyrene.
Nucleosides, Nucleotides & Nucleic Acids (29), S. 748-759.
Volltext nicht vorhanden.
Sander, Kerstin,
Kottke, Tim,
Hoffend, Claas,
Walter, Miriam,
Weizel, Lilia,
Camelin, Jean-Claude,
Ligneau, Xavier,
Schneider, Erich H. ,
Seifert, Roland,
Schwartz, Jean-Charles und
Stark, Holger
(2010)
First Metal-Containing Histamine H3 Receptor Ligands.
Organic Letters 12 (11), S. 2578-2581.
Volltext nicht vorhanden.
Brandl, Ferdinand,
Kastner, Fritz,
Gschwind, R. M. ,
Blunk, Torsten,
Teßmar, Jörg und
Göpferich, Achim
(2010)
Hydrogel-based drug delivery systems: Comparison of drug diffusivity and release kinetics.
Journal of Controlled Release 142 (2), S. 221-228.
Volltext nicht vorhanden.
Desch, M.,
Sigl, K.,
Hieke, B.,
Salb, Katharina,
Kees, Frieder,
Bernhard, D.,
Jochim, A.,
Spiessberger, B.,
Höcherl, K.,
Feil, R. ,
Lukowski, R. ,
Wegener, Jörg W.,
Hofmann, F.,
Schlossmann, Jens und
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(2010)
IRAG determines NO- and ANP-mediated smooth muscle relaxation.
Cardiovascular Research 86 (3), S. 496-505.
Volltext nicht vorhanden.
Mathar, Ilka,
Vennekens, Rudi ,
Meissner, Marcel,
Kees, Frieder,
Van der Mieren, Gerry,
Camacho Londoño, Juan E.,
Uhl, Sebastian,
Voets, Thomas ,
Hummel, Björn,
van den Bergh, An,
Herijgers, Paul ,
Nilius, Bernd,
Flockerzi, Veit,
Schweda, Frank und
Freichel, Marc
(2010)
Increased catecholamine secretion contributes to hypertension in TRPM4-deficient mice.
Journal of Clinical Investigation 120 (9), S. 3267-3279.
Volltext nicht vorhanden.
Mahboobi, Siavosh,
Sellmer, Andreas,
Winkler, Matthias,
Eichhorn, Emerich,
Pongratz, Herwig,
Ciossek, Thomas,
Baer, Thomas,
Maier, Thomas und
Beckers, Thomas
(2010)
Novel Chimeric Histone Deacetylase Inhibitors: A Series of Lapatinib Hybrides as Potent Inhibitors of Epidermal Growth Factor Receptor (EGFR), Human Epidermal Growth Factor Receptor 2 (HER2), and Histone Deacetylase Activity.
Journal of Medicinal Chemistry 53 (24), S. 8546-8555.
Volltext nicht vorhanden.
Freischmidt, A,
Jürgenliemk, G,
Kraus, B,
Okpanyi, S,
Müller, J,
Kelber, O,
Weiser, D und
Heilmann, J
(2010)
Phenolic compounds in the ethyl acetate fraction of a standardized willow bark extract.
Planta Medica 76 (12).
Volltext nicht vorhanden.
Jandt, Enrico,
Mutschke, Oliver,
Mahboobi, Siavosh,
Uecker, Andrea,
Platz, Ronny,
Berndt, Alexander,
Böhmer, Frank-D.,
Figulla, Hans R. und
Werner, Gerald S.
(2010)
Stent-based release of a selective PDGF-receptor blocker from the bis-indolylmethanon class inhibits restenosis in the rabbit animal model.
Vascular Pharmacology 52 (1-2), S. 55-62.
Volltext nicht vorhanden.
Holzhauser, C.,
Berndl, Sina,
Menacher, Florian,
Breunig, Miriam ,
Göpferich, Achim und
Wagenknecht, Hans-Achim
(2010)
Synthesis and Optical Properties of Cyanine Dyes as Fluorescent DNA Base Substitutions for Live Cell Imaging.
European Journal of Organic Chemistry (7), S. 1239-1248.
Volltext nicht vorhanden.
Emmrich, Thomas,
El-Tayeb, Ali,
Taha, Hesham,
Seifert, Roland,
Müller, Christa E. und
Link, Andreas
(2010)
Synthesis of a hydrolytically stable, fluorescent-labeled ATP analog as a tool for probing adenylyl cyclases.
Bioorganic & Medicinal Chemistry Letters 20 (1), S. 232-235.
Volltext nicht vorhanden.
Korte, G.,
Dreiseitel, A.,
Schreier, P.,
Oehme, A.,
Locher, S.,
Geiger, S.,
Heilmann, J. und
Sand, P.G.
(2010)
Tea catechins’ affinity for human cannabinoid receptors.
Phytomedicine 17 (1), S. 19-22.
Volltext nicht vorhanden.
Fürst, R,
Bubik, M,
Bihari, P,
Jürgenliemk, G,
Ammer, H,
Krombach, F,
Zahler, S und
Vollmar, A
(2010)
The hawthorn special extract WS® 1442 protects against endothelial barrier dysfunction – elucidation of the underlying molecular mechanisms.
Planta Medica 76 (12).
Volltext nicht vorhanden.
Dorn, Christoph,
Kraus, Birgit,
Motyl, Magdalena,
Weiss, Thomas S. ,
Gehrig, Manfred,
Schoelmerich, Juergen,
Heilmann, Jörg und
Hellerbrand, Claus
(2010)
Xanthohumol, a chalcon derived from hops, inhibits hepatic inflammation and fibrosis.
Molecular nutrition & food research 54 (Suppl.), S205-S213.
Volltext nicht vorhanden.
Dorn, Christoph,
Weiss, Thomas S. ,
Heilmann, Jörg und
Hellerbrand, Claus
(2010)
Xanthohumol, a prenylated chalcone derived from hops, inhibits proliferation, migration and interleukin-8 expression of hepatocellular carcinoma cells.
International journal of oncology 36 (2), S. 435-441.
Volltext nicht vorhanden.
Igel, Patrick,
Geyer, Roland,
Straßer, Andrea,
Dove, Stefan,
Seifert, Roland und
Buschauer, Armin
(2009)
Synthesis and structure-activity relationships of cyanoguanidine-type and structurally related histamine H(4) receptor agonists.
Journal of Medicinal Chemistry 52 (20), S. 6297-6313.
Volltext nicht vorhanden.
Igel, Patrick,
Schneider, Erich ,
Schnell, David,
Elz, Sigurd,
Seifert, Roland und
Buschauer, Armin
(2009)
N(G)-Acylated imidazolylpropylguanidines as potent histamine H4 receptor agonists: selectivity by variation of the N(G)-substituent.
Journal of Medicinal Chemistry 52 (8), S. 2623-2627.
Volltext nicht vorhanden.
Kraus, Anja,
Ghorai, Prasanta,
Birnkammer, Tobias,
Schnell, David,
Elz, Sigurd,
Seifert, Roland,
Dove, Stefan,
Bernhardt, Günther und
Buschauer, Armin
(2009)
N(G)-Acylated aminothiazolylpropylguanidines as potent and selective histamine H2 receptor agonists.
ChemMedChem 4 (2), S. 232-240.
Volltext nicht vorhanden.
Igel, Patrick,
Schnell, David,
Bernhardt, Günther,
Seifert, Roland und
Buschauer, Armin
(2009)
Tritium-labeled N1-[3-(1H-imidazol-4-yl)propyl]-N2-propionylguanidine ([3H]UR-PI294), a high affinity histamine H3 and H4 receptor radioligand.
ChemMedChem 4 (2), S. 225-231.
Volltext nicht vorhanden.
Kühnle, Matthias,
Egger, Michael,
Müller, Christine,
Mahringer, Anne,
Bernhardt, Günther,
Fricker, Gert ,
König, Burkhard und
Buschauer, Armin
(2009)
Potent and selective inhibitors of breast cancer resistance protein (ABCG2) derived from the p-glycoprotein (ABCB1) modulator tariquidar.
Journal of Medicinal Chemistry 52 (4), S. 1190-1197.
Volltext nicht vorhanden.
Sander, Kerstin,
Kottke, Tim,
Tanrikulu, Yusuf,
Proschak, Ewgenij,
Weizel, Lilia,
Schneider, Erich H. ,
Seifert, Roland,
Schneider, Gisbert und
Stark, Holger
(2009)
2,4-Diaminopyrimidines as histamine H4 receptor ligands—Scaffold optimization and pharmacological characterization.
Bioorganic & Medicinal Chemistry 17 (20), S. 7186-7196.
Volltext nicht vorhanden.
Romagnoli, Romeo,
Baraldi, Pier Giovanni,
Carrion, Maria Dora ,
Cruz-Lopez, Olga,
Lopez Cara, Carlota,
Basso, Giuseppe,
Viola, Giampietro ,
Khedr, Mohammed ,
Balzarini, Jan,
Mahboobi, Siavosh,
Sellmer, Andreas,
Brancale, Andrea und
Hamel, Ernest
(2009)
2-Arylamino-4-Amino-5-Aroylthiazoles. “One-Pot” Synthesis and Biological Evaluation of a New Class of Inhibitors of Tubulin Polymerization.
Journal of Medicinal Chemistry 52 (17), S. 5551-5555.
Volltext nicht vorhanden.
Amann, Thomas,
Bataille, Frauke,
Spruss, Thilo,
Mühlbauer, Marcus,
Gäbele, Erwin,
Schölmerich, Jürgen,
Kiefer, Paul,
Bosserhoff, Anja‐Katrin und
Hellerbrand, Claus
(2009)
Activated hepatic stellate cells promote tumorigenicity of hepatocellular carcinoma.
Cancer Science 100 (4), S. 646-653.
Volltext nicht vorhanden.
Hartkorn, Andreas,
Hoffmann, Florian,
Ajamieh, Hussam,
Vogel, Susanne,
Heilmann, Jörg,
Gerbes, Alexander L.,
Vollmar, Angelika M. und
Zahler, Stefan
(2009)
Antioxidant Effects of Xanthohumol and Functional Impact on Hepatic Ischemia−Reperfusion Injury.
Journal of Natural Products 72 (10), S. 1741-1747.
Volltext nicht vorhanden.
Weiser, Barbara,
Sommer, Florian,
Neubauer, M.,
Seitz, Anna Katharina,
Teßmar, Jörg ,
Göpferich, Achim und
Blunk, Torsten
(2009)
Ascorbic Acid Enhances Adipogenesis of Bone Marrow-Derived Mesenchymal Stromal Cells.
Cells Tissues Organs 189 (6), S. 373-381.
Volltext nicht vorhanden.
Rupprecht, Korbinian,
Schmidt, Christoph,
Raspé, Anne,
Schweda, Frank,
Shipkova, Maria,
Fischer, Wolfgang,
Bucher, Michael,
Kees, Frieder und
Faerber, Lothar
(2009)
Bioavailability of Mycophenolate Mofetil and Enteric‐Coated Mycophenolate Sodium Is Differentially Affected by Pantoprazole in Healthy Volunteers.
The Journal of Clinical Pharmacology 49 (10), S. 1196-1201.
Volltext nicht vorhanden.
Heidel, Florian,
Lipka, Daniel B.,
Mirea, Fian K.,
Mahboobi, Siavosh,
Grundler, Rebekka,
Kancha, Rama K.,
Duyster, Justus,
Naumann, Michael ,
Huber, Christoph,
Böhmer, Frank D. und
Fischer, Thomas
(2009)
Bis(1H‐indol‐2‐yl)methanones are effective inhibitors of FLT3‐ITD tyrosine kinase and partially overcome resistance to PKC412A in vitro.
British Journal of Haematology 144 (6), S. 865-874.
Volltext nicht vorhanden.
Göttle, Martin,
Geduhn, Jens,
König, Burkhard ,
Gille, Andreas ,
Höcherl, Klaus und
Seifert, Roland
(2009)
Characterization of Mouse Heart Adenylyl Cyclase.
Journal of Pharmacology and Experimental Therapeutics 329 (3), S. 1156-1165.
Volltext nicht vorhanden.
Mahboobi, Siavosh,
Dove, Stefan,
Sellmer, Andreas,
Winkler, Matthias,
Eichhorn, Emerich,
Pongratz, Herwig,
Ciossek, Thomas,
Baer, Thomas,
Maier, Thomas und
Beckers, Thomas
(2009)
Design of chimeric histone deacetylase- and tyrosine kinase-inhibitors: a series of imatinib hybrides as potent inhibitors of wild-type and mutant BCR-ABL, PDGF-Rbeta, and histone deacetylases.
Journal of medicinal chemistry 52 (8), S. 2265-79.
Volltext nicht vorhanden.
Suryanarayana, Srividya,
Göttle, Martin,
Hübner, Melanie,
Gille, Andreas ,
Mou, Tung-Chung,
Sprang, Stephen R.,
Richter, Mark und
Seifert, Roland
(2009)
Differential Inhibition of Various Adenylyl Cyclase Isoforms and Soluble Guanylyl Cyclase by 2′,3′-O-(2,4,6-Trinitrophenyl)-Substituted Nucleoside 5′-Triphosphates.
Journal of Pharmacology and Experimental Therapeutics 330 (3), S. 687-695.
Volltext nicht vorhanden.
Pinto, Cibele,
Hübner, Melanie,
Gille, Andreas ,
Richter, Mark,
Mou, Tung-Chung,
Sprang, Stephen R. und
Seifert, Roland
(2009)
Differential interactions of the catalytic subunits of adenylyl cyclase with forskolin analogs.
Biochemical Pharmacology 78 (1), S. 62-69.
Volltext nicht vorhanden.
Massoumi, Ramin,
Kuphal, Silke,
Hellerbrand, Claus,
Haas, Bodo ,
Wild, Peter,
Spruss, Thilo,
Pfeifer, Alexander,
Fässler, Reinhard und
Bosserhoff, Anja K.
(2009)
Down-regulation of CYLD expression by Snail promotes tumor progression in malignant melanoma.
Journal of Experimental Medicine 206 (1), S. 221-232.
Volltext nicht vorhanden.
Osten, Larissa,
Kubitza, Marion,
Gallagher, Anna Rachel,
Kastner, Jürgen,
Olbrich, Heike,
Vries, Uwe,
Kees, Frieder,
Lelongt, Brigitte,
Somlo, Stefan,
Omran, Heymut und
Witzgall, Ralph
(2009)
Doxycycline accelerates renal cyst growth and fibrosis in the pcy/pcy mouse model of type 3 nephronophthisis, a form of recessive polycystic kidney disease.
Histochemistry and Cell Biology 132 (2), S. 199-210.
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Beule, Achim G. ,
Steinmeier, Elke,
Kaftan, Holger,
Biebler, Karl-Ernst,
Gopferich, Achim ,
Wolf, Eduard und
Hosemann, Werner
(2009)
Effects of a Dexamethasone-Releasing Stent on Osteoneogenesis in a Rabbit Model.
American Journal of Rhinology & Allergy 23 (4), S. 433-436.
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Beule, A. G.,
Steinmeier, E.,
Kaftan, H.,
Biebler, K.-E.,
Göpferich, Achim,
Wolf, Eva und
Hosemann, W.
(2009)
Effects of a dexamethasone-releasing stent on osteoneogenesis in a rabbit model.
American journal of rhinology & allergy 23 (4), S. 433-436.
Volltext nicht vorhanden.
Sommer, Florian,
Brandl, Ferdinand,
Weiser, Barbara,
Teßmar, Jörg ,
Blunk, Torsten und
Göpferich, Achim
(2009)
FACS as useful tool to study distinct hyalocyte populations.
Experimental Eye Research 88 (5), S. 995-999.
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Šlapetová, Tereza,
Šmejkal, Karel ,
Innocenti, Gabbriella,
Dall’Acqua, Stefano,
Heilmann, Jörg,
Babula, Petr,
Hamzová, Eva und
Žemlička, Milan
(2009)
Glycosylated nervogenic acid derivatives from Liparis condylobulbon (Reichb.f.) leaves.
Carbohydrate Research 344 (13), S. 1770-1774.
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Tanrikulu, Yusuf,
Proschak, Ewgenij,
Werner, Tim,
Geppert, Tim,
Todoroff, Nickolay,
Klenner, Alexander,
Kottke, Tim,
Sander, Kerstin,
Schneider, Erich ,
Seifert, Roland,
Stark, Holger ,
Clark, Timothy und
Schneider, Gisbert
(2009)
Homology Model Adjustment and Ligand Screening with a Pseudoreceptor of the Human Histamine H4 Receptor.
ChemMedChem 4 (5), S. 820-827.
Volltext nicht vorhanden.
Elbakry, Asmaa,
Zaky, A.,
Liebl, Renate,
Rachel, Reinhard,
Göpferich, Achim und
Breunig, Miriam
(2009)
Layer-by-Layer Assembled Gold Nanoparticles for siRNA Delivery.
Nano Letters 9 (5), S. 2059-2064.
Volltext nicht vorhanden.
Elbakry, Asmaa,
Zaky, Alaa,
Liebl, Renate,
Rachel, Reinhard,
Goepferich, Achim und
Breunig, Miriam
(2009)
Layer-by-layer assembled gold nanoparticles for siRNA delivery.
Nano letters 9 (5), S. 2059-2064.
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Taha, H. M.,
Schmidt, J.,
Göttle, M.,
Suryanarayana, S.,
Shen, Y.,
Tang, W.-J. ,
Gille, A. ,
Geduhn, Jens,
König, Burkhard ,
Dove, Stefan und
Seifert, Roland
(2009)
Molecular Analysis of the Interaction of Anthrax Adenylyl Cyclase Toxin, Edema Factor, with 2'(3')-O-(N-(methyl)anthraniloyl)-Substituted Purine and Pyrimidine Nucleotides.
Mol. Pharmacol. 75 (3), S. 693-703.
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Appel, Bernhard,
Baumer, Julia,
Eyrich, Daniela,
Sarhan, Hatem,
Taso, S.,
Englert, Carsten ,
Göpferich, Achim,
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(2009)
Synergistic effects of growth and differentiation factor-5 (GDF-5) and insulin on expanded chondrocytes in a 3-D environment.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 17 (11), S. 1503-1512.
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Keller, Max,
Pop, Nathalie,
Hutzler, Christoph ,
Beck-Sickinger, Annette G.,
Bernhardt, Günther und
Buschauer, Armin
(2008)
Guanidine - acylguanidine bioisosteric approach in the design of radioligands: Synthesis of a tritium-labeled N(G)-propionylargininamide ([3H]UR-MK114) as a highly potent and selective neuropeptide Y Y1 receptor antagonist.
Journal of Medicinal Chemistry 51 (24), S. 8168-8172.
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Ghorai, Prasanta,
Kraus, Anja,
Keller, Max,
Götte, Carsten,
Igel, Patrick,
Schneider, Erich ,
Schnell, David,
Bernhardt, Günther,
Dove, Stefan,
Zabel, Manfred,
Elz, Sigurd,
Seifert, Roland und
Buschauer, Armin
(2008)
Acylguanidines as bioisosteres of guanidines: N(G)-acylated imidazolylpropylguanidines, a new class of histamine H2 receptor agonists.
Journal of Medicinal Chemistry 51 (22), S. 7193-7204.
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Spangler, Corinna M.,
Spangler, Christian,
Göttle, Martin,
Shen, Yuequan,
Tang, Wei-Jen ,
Seifert, Roland und
Schäferling, Michael
(2008)
A fluorimetric assay for real-time monitoring of adenylyl cyclase activity based on terbium norfloxacin.
Analytical Biochemistry 381 (1), S. 86-93.
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Pinto, Cibele,
Papa, Dan,
Hübner, Melanie,
Mou, Tung-Chung,
Lushington, Gerald H. und
Seifert, Roland
(2008)
Activation and Inhibition of Adenylyl Cyclase Isoforms by Forskolin Analogs.
Journal of Pharmacology and Experimental Therapeutics 325 (1), S. 27-36.
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Koelwel, C.,
Rothschenk, Stefan,
Fuchs-Koelwel, B.,
Gabler, B.,
Lohmann, C. und
Göpferich, Achim
(2008)
Alginate inserts loaded with epidermal growth factor for the treatment of keratoconjunctivitis sicca.
Pharmaceutical Development and Technology 13 (3), S. 221-231.
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Vogel, Susanne,
Kaufmann, Doris,
Pojarová, Michaela,
Müller, Christine,
Pfaller, Tobias,
Kühne, Sybille,
Bednarski, Patrick J. und
Angerer, Erwin von
(2008)
Aroyl hydrazones of 2-phenylindole-3-carbaldehydes as novel antimitotic agents.
Bioorganic & Medicinal Chemistry 16 (12), S. 6436-6447.
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Wagenlehner, F.M.E.,
Kees, F.,
Weidner, W.,
Wagenlehner, C. und
Naber, K.G.
(2008)
Concentrations of moxifloxacin in plasma and urine, and penetration into prostatic fluid and ejaculate, following single oral administration of 400mg to healthy volunteers.
International Journal of Antimicrobial Agents 31 (1), S. 21-26.
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Fang, Lei,
Kraus, Birgit,
Lehmann, Jochen,
Heilmann, Joerg,
Zhang, Yihua und
Decker, Michael
(2008)
Design and synthesis of tacrine–ferulic acid hybrids as multi-potent anti-Alzheimer drug candidates.
Bioorganic & Medicinal Chemistry Letters 18 (9), S. 2905-2909.
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Hubensack, Martina,
Müller, Christine,
Höcherl, Höcherl,
Fellner, Stephan,
Spruss, Thilo,
Bernhardt, Günther und
Buschauer, Armin
(2008)
Effect of the ABCB1 modulators elacridar and tariquidar on the distribution of paclitaxel in nude mice.
Journal of Cancer Research and Clinical Oncology 134 (5), S. 597-607.
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Beule, A. G.,
Scharf, C.,
Biebler, K.-E.,
Göpferich, Achim,
Steinmeier, E.,
Wolf, E.,
Hosemann, W. und
Kaftan, H.
(2008)
Effects of Topically Applied Dexamethasone on Mucosal Wound Healing Using a Drug-Releasing Stent.
The Laryngoscope 118 (11), S. 2073-2077.
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Beule, Achim G. ,
Scharf, Christian ,
Biebler, Karl‐Ernst,
Göpferich, Achim ,
Steinmeier, Elke,
Wolf, Eduard,
Hosemann, Werner und
Kaftan, Holger
(2008)
Effects of Topically Applied Dexamethasone on Mucosal Wound Healing Using a Drug‐Releasing Stent.
The Laryngoscope 118 (11), S. 2073-2077.
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Sommer, Florian,
Pollinger, Klaus,
Brandl, Ferdinand,
Weiser, Barbara,
Teßmar, Jörg ,
Blunk, Torsten und
Göpferich, Achim
(2008)
Hyalocyte proliferation and ECM accumulation modulated by bFGF and TGF-β1.
Graefe's Archive for Clinical and Experimental Ophthalmology 246 (9), S. 1275-1284.
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Weiser, Barbara,
Prantl, Lukas,
Schubert, Thomas E. O.,
Zellner, J. ,
Fischbach-Teschl, Claudia,
Spruss, Thilo,
Seitz, Anna Katharina,
Teßmar, Jörg ,
Göpferich, Achim und
Blunk, Torsten
(2008)
In Vivo Development and Long-Term Survival of Engineered Adipose Tissue Depend on In Vitro Precultivation Strategy.
Tissue Engineering Part A 14 (2), S. 275-284.
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Mahboobi, Siavosh,
Sellmer, Andreas,
Eswayah, Asma,
Elz, Sigurd,
Uecker, Andrea und
Böhmer, Frank-D.
(2008)
Inhibition of PDGFR tyrosine kinase activity by a series of novel N-(3-(4-(pyridin-3-yl)-1H-imidazol-2-ylamino)phenyl)amides: a SAR study on the bioisosterism of pyrimidine and imidazole.
European journal of medicinal chemistry 43 (7), S. 1444-1453.
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Breunig, Miriam ,
Hosza, C.,
Lungwitz, Uta,
Watanabe, K.,
Umeda, I.,
Kato, H. und
Göpferich, Achim
(2008)
Mechanistic investigation of poly(ethylene imine)-based siRNA delivery: Disulfide bonds boost intracellular release of the cargo.
Journal of Controlled Release 130 (1), S. 57-63.
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Dai, Jisen,
Jian, Jinlong,
Bosland, Maarten,
Frenkel, Krystyna,
Bernhardt, Günther und
Huang, Xi
(2008)
Roles of hormone replacement therapy and iron in proliferation of breast epithelial cells with different estrogen and progesterone receptor status.
Breast (Edinburgh, Scotland) 17 (2), S. 172-179.
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Vlachy, N.,
Merle, C.,
Touraud, D.,
Schmidt, J.,
Talmon, Y.,
Heilmann, J. und
Kunz, W.
(2008)
Spontaneous Formation of Bilayers and Vesicles in Mixtures of Single-Chain Alkyl Carboxylates: Effect of pH and Aging and Cytotoxicity Studies.
Langmuir 24 (18), S. 9983-9988.
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Egger, M.,
Pellett, P.,
Nickl, K.,
Geiger, S.,
Graetz, S.,
Seifert, R.,
Heilmann, J. und
König, B.
(2008)
Synthesis and Cannabinoid Receptor Activity of Ketoalkenes from Echinacea pallida and Non-natural Analogues.
Chem. Eur. J. 14, 10978 - 10984.
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Hellerbrand, C,
Amann, T,
Schlegel, J,
Wild, P,
Bataille, F,
Spruss, T,
Hartmann, A und
Bosserhoff, A-K
(2008)
The novel gene MIA2 acts as a tumour suppressor in hepatocellular carcinoma.
Gut 57 (2), S. 243-251.
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Schmidtko, Achim,
Gao, Wei,
König, Peter,
Heine, Sandra,
Motterlini, Roberto ,
Ruth, Peter,
Schlossmann, Jens ,
Koesling, Doris,
Niederberger, Ellen,
Tegeder, Irmgard ,
Friebe, Andreas und
Geisslinger, Gerd
(2008)
cGMP Produced by NO-Sensitive Guanylyl Cyclase Essentially Contributes to Inflammatory and Neuropathic Pain by Using Targets Different from cGMP-Dependent Protein Kinase I.
The Journal of Neuroscience 28 (34), S. 8568-8576.
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Göttle, Martin,
Dove, Stefan,
Steindel, Phillip,
Shen, Yuequan,
Tang, Wei-Jen ,
Geduhn, Jens,
König, Burkhard und
Seifert, Roland
(2007)
Molecular Analysis of the Interaction of Bordetella pertussis Adenylyl Cyclase with Fluorescent Nucleotides.
Molecular Pharmacology 72 (3), S. 526-535.
Wang, Jenna L.,
Guo, Jian-Xin,
Zhang, Qi-Yuan,
Wu, Jay J.-Q.,
Seifert, Roland und
Lushington, Gerald H.
(2007)
A conformational transition in the adenylyl cyclase catalytic site yields different binding modes for ribosyl-modified
and unmodified nucleotide inhibitors.
Bioorganic & Medicinal Chemistry 15 (8), S. 2993-3002.
Preuss, Hendrik,
Ghorai, Prasanta,
Kraus, Anja,
Dove, Stefan,
Buschauer, Armin und
Seifert, Roland
(2007)
Constitutive Activity and Ligand Selectivity of Human,
Guinea Pig, Rat, and Canine Histamine H₂ Receptors.
Journal of Pharmacology and Experimental Therapeutics 321 (3), S. 983-995.
Preuss, Hendrik,
Ghorai, Prasanta,
Kraus, Anja,
Dove, Stefan,
Buschauer, Armin und
Seifert, Roland
(2007)
Mutations of Cys-17 and Ala-271 in the Human Histamine H₂
Receptor Determine the Species Selectivity of Guanidine-Type Agonists and Increase Constitutive Activity.
Journal of Pharmacology and Experimental Therapeutics 321 (3), S. 975-982.
Kaufmann, Doris,
Pojarová, Michaela,
Vogel, Susanne,
Liebl, Renate,
Gastpar, Robert,
Gross, Dietmar,
Nishino, Tsuyuki,
Pfaller, Tobias und
Angerer, Erwin von
(2007)
Antimitotic activities of 2-phenylindole-3-carbaldehydes in human breast cancer cells.
Bioorganic & medicinal chemistry 15 (15), S. 5122-36.
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Sommer, Florian,
Kobuch, Karin,
Brandl, Ferdinand,
Wild, Brigitte,
Framme, Carsten,
Weiser, Barbara,
Tessmar, Joerg ,
Gabel, Veit-Peter,
Blunk, Torsten und
Goepferich, Achim
(2007)
Ascorbic Acid Modulates Proliferation and Extracellular Matrix Accumulation of Hyalocytes.
Tissue Engineering 13 (6), S. 1281-1289.
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Englert, Carsten ,
Blunk, Torsten,
Müller, Rainer ,
Schulze, S.,
Baumer, Julia,
Fierlbeck, J.,
Heid, I.,
Nerlich, Michael und
Hammer, J.
(2007)
Bonding of articular cartilage utilising a combination of biochemical degradation and surface cross-linking.
Arthritis Research & Therapy 9 (3), R47.
Ziemek, Ralf,
Schneider, Erich ,
Kraus, Anja,
Cabrele, Chiara ,
Beck-Sickinger, Annette G.,
Bernhardt, Günther und
Buschauer, Armin
(2007)
Determination of affinity and activity of ligands at the human neuropeptide Y Y4 receptor by flow cytometry and aequorin luminescence.
Journal of Receptors and Signal Transduction 27 (4), S. 217-233.
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Maschke, Angelika,
Becker, Christian,
Eyrich, Daniela,
Kiermaier, Josef,
Blunk, Torsten und
Göpferich, Achim
(2007)
Development of a spray congealing process for the preparation of insulin-loaded lipid microparticles and characterization thereof.
European Journal of Pharmaceutics and Biopharmaceutics 65 (2), S. 175-187.
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Schlegel, Birgit,
Laggner, Christian,
Meier, Rene ,
Langer, Thierry ,
Schnell, David,
Seifert, Roland,
Stark, Holger ,
Höltje, Hans-Dieter und
Sippl, Wolfgang
(2007)
Generation of a homology model of the human histamine H₃ receptor for ligand docking and pharmacophore-based screening.
Journal of Computer-Aided Molecular Design.
Romagnoli, Romeo,
Baraldi, Pier Giovanni,
Carrion, Maria Dora ,
Cruz-Lopez, Olga,
Preti, Delia,
Tabrizi, Mojgan Aghazadeh,
Fruttarolo, Francesca,
Heilmann, Jörg,
Bermejo, Jaime und
Estévez, Francisco
(2007)
Hybrid molecules containing benzo[4,5]imidazo[1,2-d][1,2,4]thiadiazole and α-bromoacryloyl moieties as potent apoptosis inducers on human myeloid leukaemia cells.
Bioorganic & Medicinal Chemistry Letters 17 (10), S. 2844-2848.
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Mahboobi, Siavosh,
Uecker, Andrea,
Cénac, Christophe,
Sellmer, Andreas,
Eichhorn, Emerich,
Elz, Sigurd,
Böhmer, Frank-D. und
Dove, Stefan
(2007)
Inhibition of FLT3 and PDGFR tyrosine kinase activity by bis(benzo[b]furan-2-yl)methanones.
Bioorganic & Medicinal Chemistry 15 (5), S. 2187-2197.
Volltext nicht vorhanden.
Müller, Christine,
Gross, Dietmar,
Sarli, Vasiliki,
Gartner, Michael,
Giannis, Athanassios,
Bernhardt, Günther und
Buschauer, Armin
(2007)
Inhibitors of kinesin Eg5: antiproliferative activity of monastrol analogues against human glioblastoma cells.
Cancer Chemotherapy and Pharmacology 59 (2), S. 157-164.
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Eyrich, Daniela,
Brandl, Ferdinand,
Appel, Bernhard,
Wiese, Hinrich ,
Maier, Gerhard,
Wenzel, Magdalene,
Staudenmaier, Rainer,
Goepferich, Achim und
Blunk, Torsten
(2007)
Long-term stable fibrin gels for cartilage engineering.
Biomaterials 28 (1), S. 55-65.
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Math´e, A.A.,
Gruber, S.H.M,
El Khoury, A.,
Beiderbeck, D.,
Neumann, I.D. und
Landgraf, R.
(2007)
P.4.b.002 Brain biochemistry markers differentiate between animal models of anxiety and depression.
European Neuropsychopharmacology 17, S510-S511.
Volltext nicht vorhanden.
Schertl, Sabine,
Hartmann, Rolf W.,
Batzl-Hartmann, Christine,
Spruss, Thilo,
Maucher, Anton,
Angerer, Erwin von,
Schiller, Claus D.,
Schneider, Martin R.,
Gust, Ronald und
Schönenberger, Helmut
(2007)
Platinum(II) complexes interfering with testicular steroid biosynthesis: drugs for the therapy of advanced or recurrent prostate cancers? Preclinical studies.
Journal of Cancer Research and Clinical Oncology 133 (3), S. 153-167.
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Preuss, Hendrik,
Ghorai, Prasanta,
Kraus, Anja,
Dove, Stefan,
Buschauer, Armin und
Seifert, Roland
(2007)
Point Mutations in the Second Extracellular Loop of the Histamine H2 Receptor do not affect the Species-Selective Activity of Guanidine-Type Agonists.
Naunyn Schmiedebergs Arch. Pharmacol. 376 (4), S. 253-264.
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Brandl, F.,
Henke, M.,
Rothschenk, S.,
Gschwind, R. M. ,
Breunig, M. ,
Tessmar, J.,
Goepferich, Achim und
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(2007)
Poly(ethylene glycol) based hydrogels for intraocular applications.
Advanced Engineering Materials 9 (12), S. 1141-1149.
Volltext nicht vorhanden.
Hofinger, Edith S. A.,
Spickenreither, Martin,
Oschmann, Jan,
Bernhardt, Günther,
Rudolph, Rainer und
Buschauer, Armin
(2007)
Recombinant human hyaluronidase Hyal-1: insect cells versus E. coli as expression system and identification of low molecular weight inhibitors.
Glycobiology 17 (4), S. 444-453.
Volltext nicht vorhanden.
Weber, Silke,
Bernhard, Dominik,
Lukowski, Robert,
Weinmeister, Pascal,
Wörner, René,
Wegener, Jörg W.,
Valtcheva, Nadejda,
Feil, Susanne ,
Schlossmann, Jens ,
Hofmann, Franz und
Feil, Robert
(2007)
Rescue of cGMP Kinase I Knockout Mice by Smooth Muscle–Specific Expression of Either Isozyme.
Circulation Research 101 (11), S. 1096-1103.
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Hacker, Michael ,
Ringhofer, Michael,
Appel, Bernhard,
Neubauer, Markus,
Vogel, Thomas,
Young, Simon ,
Mikos, Antonios G.,
Blunk, Torsten,
Göpferich, Achim und
Schulz, Michaela B.
(2007)
Solid lipid templating of macroporous tissue engineering scaffolds.
Biomaterials 28 (24), S. 3497-3507.
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Schneider, Erich ,
Keller, Max,
Brennauer, Albert,
Hoefelschweiger, Bianca K.,
Gross, Dietmar,
Wolfbeis, Otto S. ,
Bernhardt, Günther und
Buschauer, Armin
(2007)
Synthesis and Characterization of the First Fluorescent Nonpeptide NPY Y1 Receptor Antagonist.
ChemBioChem 8 (16), S. 1981-1988.
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Egger, Michael,
Li, Xuqin,
Müller, Christine,
Bernhardt, Günther,
Buschauer, Armin und
König, Burkhard
(2007)
Tariquidar analogues: synthesis by Cu(I)-catalysed N/O–aryl coupling and inhibitory activity against the ABCB1 transporter.
European Journal of Organic Chemistry 2007 (16), S. 2643-2649.
Volltext nicht vorhanden.
Pojarová, Michaela,
Kaufmann, Doris,
Gastpar, Robert,
Nishino, Tsuyuki,
Reszka, Przemyslaw,
Bednarski, Patrick J. und
Angerer, Erwin von
(2007)
[(2-Phenylindol-3-yl)methylene]propanedinitriles inhibit the growth of breast cancer cells by cell cycle arrest in G(2)/M phase and apoptosis.
Bioorganic & medicinal chemistry 15 (23), S. 7368-7379.
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Amann, T.,
Spruss, T.,
Bataille, F.,
Liedtke, C.,
Muhlbauer, M.,
Trautwein, C.,
Bosserhoff, A.K. und
Hellerbrand, C.
(2007)
[69] IDENTIFICATION OF FIBROBLAST GROWTH FACTOR RECEPTOR 2IIIB (FGFR2IIIB) AS TUMOR SUPPRESSOR IN HEPATOCANCEROGENESIS.
Journal of Hepatology 46, S31.
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Kees, Frieder,
Bucher, Michael,
Schweda, Frank,
Gschaidmeier, Harald,
Burhenne, Juergen ,
Mikus, Gerd und
Faerber, Lothar
(2006)
Comparative bioavailability of the microemulsion formulation of cyclosporine (Neoral) with a generic dispersion formulation (Cicloral) in young healthy male volunteers.
Therapeutic drug monitoring 28 (3), S. 312-320.
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Xie, Sheng-Xue,
Kraus, Anja,
Ghorai, Prasanta,
Ye, Qi-Zhuang,
Elz, Sigurd,
Buschauer, Armin und
Seifert, Roland
(2006)
N1-(3-Cyclohexylbutanoyl)-N2-[3-(1H-imidazol-4-
yl)propyl]guanidine (UR-AK57), a Potent Partial Agonist for the Human Histamine H1- and H2- Receptors.
Journal of Pharmacology and Experimental Therapeutics 317 (3), S. 1262-1268.
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Wabnitz, Tobias C.,
Rizzo, Simona ,
Götte, Carsten,
Buschauer, Armin,
Benincori, Tiziana und
Reiser, Oliver
(2006)
Enantioselective hydrogenation of diaryl-substituted a,b-unsaturated nitriles.
Tetrahedron Letters 47 (22), S. 3733-3736.
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Bucher, Michael,
Kees, Frieder K.,
Messmann, Barbara,
Lunz, Dirk,
Rath, Stephan,
Zelenka, Marek,
Schlitt, Hans J. und
Hobbhahn, Jonny
(2006)
Prostaglandin I2 release following mesenteric traction during abdominal surgery is mediated by cyclooxygenase-1.
European journal of pharmacology 536 (3), S. 296-300.
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Mahboobi, Siavosh,
Eichhorn, Emerich,
Popp, Alfred,
Sellmer, Andreas,
Elz, Sigurd und
Möllmann, Ute
(2006)
3-Bromo-4-(1H-3-indolyl)-2,5-dihydro-1H-2,5-pyrroledione derivatives as new lead compounds for antibacterially active substances.
European Journal of Medicinal Chemistry 41 (2), S. 176-191.
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Hellerbrand, C.,
Amann, T.,
Schlegel, J.,
Spruss, T.,
Bataille, F.,
Hartmann, A.,
Mühlbauer, M.,
Schölmerich, J. und
Bosserhoff, A.K.
(2006)
98 The novel gene MIA2 promotes progression of hepatocellular carcinoma.
Journal of Hepatology 44, S43.
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Schneider, Erich ,
Mayer, Matthias,
Ziemek, Ralf,
Li, Liantao,
Hutzler, Christoph ,
Bernhardt, Günther und
Buschauer, Armin
(2006)
A Simple and Powerful Flow Cytometric Method for the Simultaneous Determination of Multiple Parameters at G-Protein-coupled Receptor Subtypes.
ChemBioChem 7 (9), S. 1400-1409.
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Guse, C.,
Koennings, S.,
Maschke, A.,
Hacker, M. ,
Becker, C.,
Schreiner, S.,
Blunk, T.,
Spruss, T. und
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Biocompatibility and erosion behavior of implants made of triglycerides and blends with cholesterol and phospholipids.
International Journal of Pharmaceutics 314 (2), S. 153-160.
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Fischer, Thomas,
Bohmer, Frank D.,
Huber, Christoph,
Dove, Stefan,
Breitenbucher, Frank,
Mirea, Fian K. und
Heidel, Florian
(2006)
Bis(1H-indol-2yl)methanones Are Effective Inhibitors of Mutated FLT3 Tyrosine Kinase, Overcome Resistance to PKC412A In Vitro and Show Synergy with Chemotherapy.
Blood 108 (11), S. 1369.
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Mou, Tung-Chung,
Gille, Andreas ,
Suryanarayana, Srividya,
Richter, Mark,
Seifert, Roland und
Sprang, Stephen R.
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Broad Specificity of Mammalian Adenylyl Cyclase for Interaction with 2′,3′-Substituted Purine- and Pyrimidine Nucleotide Inhibitors.
Molecular Pharmacology 70 (3), S. 878-886.
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Rigden, Daniel J. ,
Botzki, Alexander ,
Nukui, Masatoshi,
Mewbourne, R. Brandon,
Lamani, Ejvis,
Braun, Stephan,
von Angerer, Erwin,
Bernhardt, Günther,
Dove, Stefan,
Buschauer, Armin und
Jedrzejas, Mark J.
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Design of new benzoxazole-2-thione derived inhibitors of Streptococcus pneumoniae hyaluronan lyase: structure of a complex with a 2-phenylindole.
Glycobiology 16 (8), S. 757-765.
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Guse, C.,
Koennings, S.,
Kreye, F.,
Siepmann, F. ,
Goepferich, A. und
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Drug release from lipid-based implants: Elucidation of the underlying mass transport mechanisms.
International Journal of Pharmaceutics 314 (2), S. 137-144.
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Kelber, O. ,
Wittwer, A.,
Lapke, C.,
Kroll, U.,
Weiser, D.,
Okpanyi, S.N. und
Heilmann, J.
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Ex vivo/in vitro absorption of STW 5 (Iberogast®) and its extract components.
Phytomedicine 13, S. 107-113.
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Koennings, S.,
Garcion, E.,
Faisant, N.,
Menei, P.,
Benoit, J.P. und
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In vitro investigation of lipid implants as a controlled release system for interleukin-18.
International Journal of Pharmaceutics 314 (2), S. 145-152.
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Appel, B.,
Maschke, A.,
Weiser, B.,
Sarhan, H.,
Englert, C. ,
Angele, P.,
Blunk, T. und
Göpferich, A.
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Lipidic implants for controlled release of bioactive insulin: Effects on cartilage engineered in vitro.
International Journal of Pharmaceutics 314 (2), S. 170-178.
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Weinrich, Malte,
Scheingraber, Stefan,
Stremovskaia, Tatiana,
Schilling, Martin K.,
Kees, Frieder und
Pistorius, Georg A.
(2006)
Liver tissue concentrations of levofloxacin after single intravenous administration of 500mg for antibiotic prophylaxis in liver surgery.
International Journal of Antimicrobial Agents 28 (3), S. 221-225.
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Knerr, Robert,
Weiser, Barbara,
Drotleff, Sigrid,
Steinem, Claudia und
Göpferich, Achim
(2006)
Measuring Cell Adhesion on RGD‐Modified, Self‐Assembled PEG Monolayers Using the Quartz Crystal Microbalance Technique.
Macromolecular Bioscience 6 (10), S. 827-838.
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Maschke, Angelika,
Calí, Nadia,
Appel, Bernhard,
Kiermaier, Josef,
Blunk, Torsten und
Göpferich, Achim
(2006)
Micronization of Insulin by High Pressure Homogenization.
Pharmaceutical Research 23 (9), S. 2220-2229.
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Heilmann, J,
Htay Shwe, H,
Aye, M,
Sein, MM,
Kreitmeier, P und
Reiser, O
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New Furostanol Glycosides from the Rhizomes of Tacca integrifolia.
Planta Medica 72 (11).
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Mahboobi, Siavosh,
Uecker, Andrea,
Sellmer, Andreas,
Cénac, Christophe,
Höcher, Heymo,
Pongratz, Herwig,
Eichhorn, Emerich,
Hufsky, Harald,
Trümpler, Antje,
Sicker, Marit,
Heidel, Florian,
Fischer, Thomas,
Stocking, Carol,
Elz, Sigurd,
Böhmer, Frank-D. und
Dove, Stefan
(2006)
Novel Bis(1H-indol-2-yl)methanones as Potent Inhibitors of FLT3 and Platelet-Derived Growth Factor Receptor Tyrosine Kinase.
Journal of Medicinal Chemistry 49 (11), S. 3101-3115.
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Elkharraz, K.,
Faisant, N.,
Guse, C.,
Siepmann, F. ,
Arica-Yegin, B.,
Oger, J.M.,
Gust, R.,
Goepferich, A. ,
Benoit, J.P. und
Siepmann, J.
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Paclitaxel-loaded microparticles and implants for the treatment of brain cancer: Preparation and physicochemical characterization.
International Journal of Pharmaceutics 314 (2), S. 127-136.
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Xie, Sheng-Xue,
Petrache, Georgiana,
Schneider, Erich ,
Ye, Qi-Zhuang,
Bernhardt, Günther,
Seifert, Roland und
Buschauer, Armin
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Synthesis and pharmacological characterization of novel fluorescent histamine H2-receptor ligands derived from aminopotentidine.
Bioorganic & Medicinal Chemistry Letters 16 (15), S. 3886-3890.
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Neubauer, Markus,
Hacker, Michael ,
Bauer-Kreisel, Petra,
Weiser, Barbara,
Fischbach, Claudia ,
Schulz, Michaela B,
Goepferich, Achim und
Blunk, Torsten
(2005)
Adipose Tissue Engineering Based on Mesenchymal Stem Cells and Basic Fibroblast Growth Factorin Vitro.
Tissue Engineering 11 (11-12), S. 1840-1851.
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Gille, Andreas ,
Guo, Jianxin,
Mou, Tung-Chung,
Doughty, Michael B.,
Lushington, Gerald H. und
Seifert, Roland
(2005)
Differential interactions of G-proteins and adenylyl cyclase with nucleoside 5′-triphosphates, nucleoside 5′-[γ-thio]triphosphates and nucleoside 5′-[β,γ-imido]triphosphates.
Biochemical Pharmacology 71 (1-2), S. 89-97.
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Breunig, Miriam ,
Lungwitz, Uta,
Liebl, Renate,
Fontanari, Claudia,
Klar, Juergen,
Kurtz, Armin,
Blunk, Torsten und
Goepferich, Achim
(2005)
Gene delivery with low molecular weight linear polyethylenimines.
The Journal of Gene Medicine 7 (10), S. 1287-1298.
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Ito, Natsuho,
Ito, Taisuke,
Kromminga, Arno,
Bettermann, Albrecht,
Takigawa, Masahiro,
Kees, Frieder,
Straub, Rainer H. und
Paus, Ralf
(2005)
Human hair follicles display a functional equivalent of the hypothalamic‐pituitary‐adrenal (HPA) axis and synthesize cortisol.
The FASEB Journal 19 (10), S. 1332-1334.
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Lieb, E.,
Hacker, M. ,
Tessmar, J. ,
Kunz-Schughart, L.A.,
Fiedler, J.,
Dahmen, C.,
Hersel, U.,
Kessler, H.,
Schulz, M.B. und
Göpferich, A.
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Mediating specific cell adhesion to low-adhesive diblock copolymers by instant modification with cyclic RGD peptides.
Biomaterials 26 (15), S. 2333-2341.
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Salmen, Sunnhild,
Hoechstetter, Julia,
Käsbauer, Christian,
Paper, Dieter H.,
Bernhardt, Günther und
Buschauer, Armin
(2005)
Sulphated Oligosaccharides as Inhibitors of Hyaluronidases from Bovine Testis, Bee Venom and Streptococcus agalactiae.
Planta Med. 71, S. 727-732.
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Romagnoli, Romeo,
Baraldi, Pier Giovanni,
Iaconinoto, Maria Antonietta,
Carrion, Maria Dora ,
Tabrizi, Mojgan Aghazadeh,
Gambari, Roberto ,
Borgatti, Monica und
Heilmann, Jörg
(2005)
Synthesis and biological activity of alpha-bromoacryloyl lexitropsin conjugates.
European Journal of Medicinal Chemistry 40 (11), S. 1123-1128.
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Mahboobi, Siavosh,
Sellmer, Andreas,
Eichhorn, Emerich,
Beckers, Thomas,
Fiebig, Heinz-Herbert und
Kelter, Gerhard
(2005)
Synthesis and cytotoxic activity of 2-acyl-1H-indole-4,7-diones on human cancer cell lines.
European Journal of Medicinal Chemistry 40 (1), S. 85-92.
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Kaftan, H.,
Hosemann, W.,
Junghans, D.,
Göpferich, A.,
Schindler, E. und
Beule, A.
(2005)
Traumatische Trommelfellperforationen.
HNO 53 (6), S. 539-544.
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Kießling, Stephan,
Müller-Newen, Gerhard,
Leeb, Sandra N.,
Hausmann, Martin,
Rath, Heiko C.,
Strater, Jörn,
Spottl, Tanja,
Schlottmann, Klaus,
Grossmann, Johannes,
Montero-Julian, F. A.,
Schölmerich, Jürgen,
Andus, Tilo,
Buschauer, Armin,
Heinrich, Peter C. und
Rogler, Gerhard
(2004)
Functional Expression of the Interleukin-11 Receptor α-Chain and Evidence of Antiapoptotic Effects in Human Colonic Epithelial Cells.
The Journal of Biological Chemistry 279 (11), S. 10304-10315.
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Neubauer, Markus,
Fischbach, Claudia ,
Bauer-Kreisel, Petra,
Lieb, Esther,
Hacker, Michael ,
Tessmar, Joerg ,
Schulz, Michaela B.,
Goepferich, Achim und
Blunk, Torsten
(2004)
Basic fibroblast growth factor enhances PPARγ ligand‐induced adipogenesis of mesenchymal stem cells.
FEBS Letters 577 (1-2), S. 277-283.
Volltext nicht vorhanden.
Ménard, Rozenn,
Alban, Susanne,
de Ruffray, Patrice,
Jamois, Frank,
Franz, Gerhard,
Fritig, Bernard,
Yvin, Jean-Claude und
Kauffmann, Serge
(2004)
Beta-1,3 glucan sulfate, but not beta-1,3 glucan, induces the salicylic acid signaling pathway in tobacco and Arabidopsis.
The Plant Cell 16 (11), S. 3020-3032.
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Drotleff, S,
Lungwitz, U,
Breunig, M ,
Dennis, A,
Blunk, T,
Tessmar, J und
Göpferich, A
(2004)
Biomimetic polymers in pharmaceutical and biomedical sciences.
European Journal of Pharmaceutics and Biopharmaceutics 58 (2), S. 385-407.
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Bernhardt, Günther,
Brunner, Henri,
Gruber, Nick,
Lottner, Christian,
Pushpan, Simi K.,
Tsuno, Takashi und
Zabel, Manfred
(2004)
Carboplatin derivatives with superior antitumor activity compared to the parent compound.
Inorganica Chimica Acta 357 (15), S. 4452-4466.
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Dittmar, Michael,
Kiourkenidis, Georgios,
Horn, Markus,
Bollwein, Susanne und
Bernhardt, Günther
(2004)
Cerebral Ischemia, Matrix Metalloproteinases, and TNF-α: MMP Inhibitors May Act Not Exclusively by Reducing MMP Activity.
Stroke 35 (7).
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Gürtler, Ulrich,
Fuchs, Peter,
Stangelmayer, Achim,
Bernhardt, Günther,
Buschauer, Armin und
Spruss, Thilo
(2004)
Construction and validation of a microprocessor controlled extracorporal circuit in rats for the optimization of isolated limb perfusion.
Archiv der Pharmazie 33 (12), S. 672-681.
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Lieb, E.,
Milz, S. ,
Vogel, T.,
Hacker, M. ,
Dauner, M. und
Schulz, M.B.
(2004)
Effects of Transforming Growth Factor β1 on Bonelike Tissue Formation in Three-Dimensional Cell Culture. I. Culture Conditions and Tissue Formation.
Tissue Engineering 10 (9-10), S. 1399-1413.
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Demirci, Betül ,
Paper, Dietrich H.,
Demirci, Fatih ,
Başer, K. Hüsnü Can und
Franz, Gerhard
(2004)
Essential Oil of Betula pendula Roth. Buds.
Evidence-based complementary and alternative medicine : eCAM 1 (3), S. 301-303.
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Fischbach, Claudia ,
Spruß, Thilo,
Weiser, Barbara,
Neubauer, Markus,
Becker, Christian,
Hacker, Michael ,
Göpferich, Achim und
Blunk, Torsten
(2004)
Generation of mature fat pads in vitro and in vivo utilizing 3-D long-term culture of 3T3-L1 preadipocytes.
Experimental Cell Research 300 (1), S. 54-64.
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Breunig, Miriam ,
Lungwitz, Uta,
Klar, Juergen,
Kurtz, Armin,
Blunk, Torsten und
Goepferich, Achim
(2004)
Polyplexes of Polyethylenimine and per-N-methylated Polyethylenimine-Cytotoxicity and Transfection Efficiency.
Journal of Nanoscience and Nanotechnology 4 (5), S. 512-520.
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WELSH, Michael ,
WELSH, Charlotte ,
EKMAN, Maria,
DIXELIUS, Johan,
HÄGERKVIST, Robert,
ANNERÉN, Cecilia,
ÅKERBLOM, Björn,
MAHBOOBI, Siavosh,
CHANDRASEKHARAN, Subhashini und
LIU, Edison T.
(2004)
The tyrosine kinase FRK/RAK participates in cytokine-induced islet cell cytotoxicity.
Biochemical Journal 382 (1), S. 261-268.
Volltext nicht vorhanden.
Fuchs-Koelwel, B.,
Koelwel, C.,
G�pferich, A.,
Gabler, B.,
Wiegrebe, E. und
Lohmann, C. P.
(2004)
Vertr�glichkeit eines neuen Kalzium-Alginat-Insertes zur kontrollierten medikament�sen Therapie am Auge.
Der Ophthalmologe 101 (5), S. 496-499.
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Schertl, Sabine,
Hartmann, Rolf W.,
Batzl-Hartmann, Christine,
Bernhardt, Günther,
Spruß, Thilo,
Beckenlehner, Karin,
Koch, Marion,
Krauser, Rudolf,
Schlemmer, Richard,
Gust, Ronald und
Schönenberger, Helmut
(2004)
[1, 2-Bis(2, 6-difluoro-3-hydroxyphenyl)ethylene-diamine]platinum(II) complexes, compounds for the endocrine therapy of breast cancer - mode of action I: antitumor activity due to the reduction of the endogenous estrogen level.
Archiv der Pharmazie 337 (6), S. 335-348.
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Schertl, Sabine,
Hartmann, Rolf W.,
Batzl-Hartmann, Christine,
Bernhardt, Günther,
Spruss, Thilo,
Beckenlehner, Karin,
Koch, Marion,
Krauser, Rudolf,
Schlemmer, Richard,
Gust, Ronald und
Schönenberger, Helmut
(2004)
[1, 2-Bis(2, 6-difluoro-3-hydroxyphenyl)ethylene-diamine]platinum(II) complexes, compounds for the endocrine therapy of breast cancer - mode of action II: contribution of drug inactivation, cellular drug uptake and sterical factors in the drug-target interaction to the antitumor activity.
Archiv der Pharmazie 337 (6), S. 349-359.
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Botzki, Alexander ,
Rigden, Daniel J. ,
Braun, Stephan,
Nukui, Masatoshi,
Salmen, Sunnhild,
Hoechstetter, Julia,
Bernhardt, Günther,
Dove, Stefan,
Jedrzejas, Mark J. und
Buschauer, Armin
(2004)
l-Ascorbic Acid 6-Hexadecanoate, a Potent Hyaluronidase Inhibitor.
Journal of Biological Chemistry 279 (44), S. 45990-45997.
Volltext nicht vorhanden.
Li, Liantao,
Mayer, Matthias,
Schneider, Erich ,
Schreiber, Elvira,
Bernhardt, Günther,
Peng, Shiqi und
Buschauer, Armin
(2003)
Preparation of fluorescent nonpeptidic neuropeptide Y receptor ligands: analogues of the quinazoline-type anti-obesity Y5 antagonist CGP 71683A.
Arch Pharm (Weinheim) 336 (12), S. 585-590.
Volltext nicht vorhanden.
Böhmer, Frank D.,
Karagyozov, Luchezar,
Uecker, Andrea,
Serve, Hubert,
Botzki, Alexander ,
Mahboobi, Siavosh und
Dove, Stefan
(2003)
A Single Amino Acid Exchange Inverts Susceptibility of Related Receptor Tyrosine Kinases for the ATP Site Inhibitor STI-571.
Journal of Biological Chemistry 278 (7), S. 5148-5155.
Volltext nicht vorhanden.
Iwasa, Kinuko,
Kuribayashi, Ayako,
Sugiura, Makiko,
Moriyasu, Masataka,
Lee, Dong-Ung und
Wiegrebe, Wolfgang
(2003)
LC–NMR and LC–MS analysis of 2,3,10,11-oxygenated protoberberine metabolites in Corydalis cell cultures.
Phytochemistry 64 (7), S. 1229-1238.
Volltext nicht vorhanden.
Vogelhuber, W.,
Magni, E.,
Mouro, M.,
Spruß, T.,
Guse, C.,
Gazzaniga, A. und
Göpferich, A.
(2003)
Monolithic Triglyceride Matrices: A Controlled-Release System for Proteins.
Pharmaceutical Development and Technology 8 (1), S. 71-79.
Volltext nicht vorhanden.
Menghin, Sonja,
Pertz, Heinz H.,
Kramer, Kai,
Seifert, Roland,
Schunack, Walter und
Elz, Sigurd
(2003)
Nα-Imidazolylalkyl and Pyridylalkyl Derivatives of Histaprodifen: Synthesis and in Vitro Evaluation of Highly Potent Histamine H1-Receptor Agonists.
Journal of Medicinal Chemistry 46 (25), S. 5458-5470.
Volltext nicht vorhanden.
Lieb, E.,
Tessmar, J. ,
Hacker, M. ,
Fischbach, C. ,
Rose, D.,
Blunk, T.,
Mikos, A.G.,
Göpferich, A. und
Schulz, M.B.
(2003)
Poly(D,L-lactic acid)-Poly(ethylene glycol)-Monomethyl Ether Diblock Copolymers Control Adhesion and Osteoblastic Differentiation of Marrow Stromal Cells.
Tissue Engineering 9 (1), S. 71-84.
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Krenn, Liselotte ,
Presser, Armin,
Pradhan, Riddhi,
Bahr, Beate,
Paper, Dietrich H.,
Mayer, Klaus K. und
Kopp, Brigitte
(2003)
Sulfemodin 8-O-β-d-Glucoside, a New Sulfated Anthraquinone Glycoside, and Antioxidant Phenolic Compounds from Rheum emodi.
Journal of Natural Products 66 (8), S. 1107-1109.
Volltext nicht vorhanden.
Govoni, Marinella,
Bakker, Remko A.,
van de Wetering, Ineke,
Smit, Martine J.,
Menge, Wiro M. B. P.,
Timmerman, Henk,
Elz, Sigurd,
Schunack, Walter und
Leurs, Rob
(2003)
Synthesis and Pharmacological Identification of Neutral Histamine H1-Receptor Antagonists.
Journal of Medicinal Chemistry 46 (26), S. 5812-5824.
Volltext nicht vorhanden.
Li, Liantao,
Kracht, Julia,
Peng, Shiqi,
Bernhardt, Günther und
Buschauer, Armin
(2003)
Synthesis and pharmacological activity of fluorescent histamine H1 receptor antagonists related to mepyramine,.
Bioorganic & Medicinal Chemistry Letters 13 (7), S. 1245-1248.
Volltext nicht vorhanden.
Radons, Jürgen,
Dove, Stefan,
Neumann, Detlef ,
Altmann, Reinhold,
Botzki, Alexander ,
Martin, Michael U. und
Falk, Werner
(2003)
The Interleukin 1 (IL-1) Receptor Accessory Protein Toll/IL-1 Receptor Domain.
Journal of Biological Chemistry 278 (49), S. 49145-49153.
Volltext nicht vorhanden.
Hacker, Michael ,
Tessmar, Jörg ,
Neubauer, Markus,
Blaimer, Andrea,
Blunk, Torsten,
Göpferich, Achim und
Schulz, Michaela B
(2003)
Towards biomimetic scaffolds: Anhydrous scaffold fabrication from biodegradable amine-reactive diblock copolymers.
Biomaterials 24 (24), S. 4459-4473.
Volltext nicht vorhanden.
Kees, Martin G.,
Pongratz, Georg ,
Kees, Frieder,
Schölmerich, Jürgen und
Straub, Rainer H.
(2003)
Via β-adrenoceptors, stimulation of extrasplenic sympathetic nerve fibers inhibits lipopolysaccharide-induced TNF secretion in perfused rat spleen.
Journal of Neuroimmunology 145 (1-2), S. 77-85.
Volltext nicht vorhanden.
Lucke, Andrea,
Kiermaier, Josef und
Göpferich, Achim
(2002)
Nicht ausgewählt
Pharmaceutical Research 19 (2), S. 175-181.
Volltext nicht vorhanden.
Parker, S. L.,
Parker, M. S.,
Lundell, I.,
Balasubramaniam, A.,
Buschauer, Armin,
Kane, J. K.,
Yalcin, A. und
Berglund, M. M.
(2002)
Agonist internalization by cloned Y1 neuropeptide Y (NPY) receptor in Chinese hamster ovary cells shows strong preference for NPY, endosome-linked entry and fast receptor recycling.
Regulatory Peptides 107 (1-3), S. 49-62.
Volltext nicht vorhanden.
Apers, Sandra,
Paper, Dietrich,
Bürgermeister, Jutta,
Baronikova, Slavka,
Van Dyck, Stefaan,
Lemière, Guy,
Vlietinck, Arnold und
Pieters, Luc
(2002)
Antiangiogenic Activity of Synthetic Dihydrobenzofuran Lignans.
Journal of Natural Products 65 (5), S. 718-720.
Volltext nicht vorhanden.
Teller, S,
Krämer, D,
Böhmer, S-A,
Tse, KF,
Small, D,
Mahboobi, S,
Wallrapp, C,
Beckers, T,
Kratz-Albers, K,
Schwäble, J,
Serve, H und
Böhmer, F-D
(2002)
Bis(1H-2-indolyl)-1-methanones as inhibitors of the hematopoietic tyrosine kinase Flt3.
Leukemia 16 (8), S. 1528-1534.
Volltext nicht vorhanden.
Mahboobi, Siavosh,
Teller, Steffen,
Pongratz, Herwig,
Hufsky, Harald,
Sellmer, Andreas,
Botzki, Alexander ,
Uecker, Andrea,
Beckers, Thomas,
Baasner, Silke,
Schächtele, Christoph,
Überall, Florian,
Kassack, Matthias U.,
Dove, Stefan und
Böhmer, Frank-D.
(2002)
Bis(1H-2-indolyl)methanones as a Novel Class of Inhibitors of the Platelet-Derived Growth Factor Receptor Kinase.
Journal of Medicinal Chemistry 45 (5), S. 1002-1018.
Volltext nicht vorhanden.
Gooch, K.J.,
Blunk, T.,
Courter, D.L.,
Sieminski, A.L.,
Vunjak-Novakovic, G. und
Freed, L.E.
(2002)
Bone Morphogenetic Proteins-2, -12, and -13 Modulatein VitroDevelopment of Engineered Cartilage.
Tissue Engineering 8 (4), S. 591-601.
Volltext nicht vorhanden.
Kellner, Karin,
Liebsch, Gregor,
Klimant, Ingo,
Wolfbeis, Otto S. ,
Blunk, Torsten,
Schulz, Michaela B. und
Göpferich, Achim
(2002)
Determination of oxygen gradients in engineered tissue using a fluorescent sensor.
Biotechnology and Bioengineering 80 (1), S. 73-83.
Zugang zum Volltext eingeschränkt.
Blunk, Torsten,
Sieminski, Alisha L.,
Gooch, Keith J.,
Courter, Donald L.,
Hollander, Anthony P.,
Nahir, A. Menahem,
Langer, Robert,
Vunjak-Novakovic, Gordana und
Freed, Lisa E.
(2002)
Differential Effects of Growth Factors on Tissue-Engineered Cartilage.
Tissue Engineering 8 (1), S. 73-84.
Volltext nicht vorhanden.
El-Subbagh, Hussein,
Wittig, Thomas,
Decker, Michael,
Elz, Sigurd,
Nieger, Martin und
Lehmann, Jochen
(2002)
Dopamine/Serotonin Receptor Ligands. Part IV [1]: Synthesis and Pharmacology of Novel 3-Benzazecines and 3-Benzazonines as Potential 5-HT2A and Dopamine Receptor Ligands.
Archiv der Pharmazie 335 (9), S. 443-448.
Volltext nicht vorhanden.
Machein, U.,
Buss, B.,
Spiller, I.,
Braun, J.,
Rudwaleit, M.,
Faerber, L. und
Sieper, J.
(2002)
Effective treatment of early rheumatoid arthritis with a combination of methotrexate, prednisolone and cyclosporin.
Rheumatology 41 (1), S. 110-111.
Volltext nicht vorhanden.
Kellner, Karin,
Lang, Kurt,
Papadimitriou, Apollon,
Leser, Ulrike,
Milz, Stefan ,
Schulz, Michaela B.,
Blunk, Torsten und
Göpferich, Achim
(2002)
Effects of Hedgehog Proteins on Tissue Engineering of Cartilagein Vitro.
Tissue Engineering 8 (4), S. 561-572.
Volltext nicht vorhanden.
Vogelhuber, Werner,
Spruß, Thilo,
Bernhardt, Günther,
Buschauer, Armin und
Göpferich, Achim
(2002)
Efficacy of BCNU and paclitaxel loaded subcutaneous implants in the interstitial chemotherapy of U-87 MG human glioblastoma xenografts,.
International Journal of Pharmaceutics 238 (1-2), S. 111-121.
Volltext nicht vorhanden.
Bernhardt, Günther,
Beckenlehner, Karin,
Spruß, Thilo,
Schlemmer, Richard,
Reile, Herta und
Schönenberger, Helmut
(2002)
Establishment and Characterization of New Murine Breast Cancer Cell Lines.
Archiv der Pharmazie 335 (2-3), S. 55-68.
Volltext nicht vorhanden.
Sasse, Astrid ,
Ligneau, Xavier,
Rouleau, Agnès,
Elz, Sigurd,
Ganellin, C. Robin,
Arrang, Jean-Michel,
Schwartz, Jean-Charles,
Schunack, Walter und
Stark, Holger
(2002)
Influence of Bulky Substituents on Histamine H3Receptor Agonist/Antagonist Properties.
Journal of Medicinal Chemistry 45 (18), S. 4000-4010.
Volltext nicht vorhanden.
Bürgermeister, Jutta,
Paper, Dietrich H,
Vogl, Horst,
Linhardt, Robert J und
Franz, Gerhard
(2002)
LaPSvS1, a (1→3)-β-galactan sulfate and its effect on angiogenesis in vivo and in vitro.
Carbohydrate Research 337 (16), S. 1459-1466.
Volltext nicht vorhanden.
Weiss, Thomas S. ,
Bernhardt, Günther,
Buschauer, Armin,
Thasler, Wolfgang E.,
Dolgner, Doris,
Zirngibl, Hubert und
Jauch, Karl-Walter
(2002)
Polyamine levels of human colorectal adenocarcinomas are correlate with tumor stage and grade,.
International Journal of Colorectal Disease 17 (6), S. 381-387.
Volltext nicht vorhanden.
Graßmann, Sven,
Sadek, Bassem,
Ligneau, Xavier,
Elz, Sigurd,
Ganellin, C.Robin,
Arrang, Jean-Michel,
Schwartz, Jean-Charles,
Stark, Holger und
Schunack, Walter
(2002)
Progress in the proxifan class: heterocyclic congeners as novel potent and selective histamine H3-receptor antagonists.
European Journal of Pharmaceutical Sciences 15 (4), S. 367-378.
Volltext nicht vorhanden.
Höcherl, K.,
Kammerl, M.,
Kees, F.,
Krämer, B. K.,
Grobecker, H. F. und
Kurtz, A.
(2002)
Role of renal nerves in stimulation of renin, COX-2, and nNOS in rat renal cortex during salt deficiency.
American Journal of Physiology-Renal Physiology 282 (3), F478-F484.
Volltext nicht vorhanden.
Lucke, Andrea,
Fustella, Elisabetta,
Teßmar, Jörg ,
Gazzaniga, Andrea und
Göpferich, Achim
(2002)
The effect of poly(ethylene glycol)–poly(d,l-lactic acid) diblock copolymers on peptide acylation.
Journal of Controlled Release 80 (1-3), S. 157-168.
Volltext nicht vorhanden.
Fellner, Stephan,
Bauer, Björn,
Miller, David S.,
Schaffrik, Martina,
Fankhänel, Martina,
Spruß, Thilo,
Bernhardt, Günther,
Graeff, Claudia,
Färber, Lothar,
Gschaidmeier, Harald,
Buschauer, Armin und
Fricker, Gert
(2002)
Transport of paclitaxel (Taxol) across the blood-brain barrier in vitro and in vivo.
Journal of Clinical Investigation 110 (9), S. 1309-1318.
Volltext nicht vorhanden.
Schertl, Sabine,
Hartmann, Rolf W.,
Batzl-Hartmann, Christine,
Schlemmer, Richard,
Spruß, Thilo,
Bernhardt, Günther,
Gust, Ronald und
Schönenberger, Helmut
(2001)
1-(2,6-Dichloro-4-hydroxyphenyl)-2-phenylethanes — New Biological Response Modifiers for the Therapy of Breast Cancer. Synthesis and Evaluation of Estrogenic/Antiestrogenic Properties.
Archiv der Pharmazie 334 (4), S. 125-137.
Volltext nicht vorhanden.
Mann, Bianca,
Hartner, Andrea,
Jensen, Boye L.,
Hilgers, Karl F.,
Höcherl, Klaus,
Krämer, Bernhard K. und
Kurtz, Armin
(2001)
Acute upregulation of COX-2 by renal artery stenosis.
American Journal of Physiology-Renal Physiology 280 (1), F119-F125.
Volltext nicht vorhanden.
Wolf, Konrad,
Kurtz, Armin,
Pfeifer, Michael,
Höcherl, Klaus,
Riegger, Günter und
Krämer, Bernhard
(2001)
Different regulation of left ventricular ANP, BNP and adrenomedullin mRNA in the two-kidney, one-clip model of renovascular hypertension.
Pfl�gers Archiv European Journal of Physiology 442 (2), S. 212-217.
Volltext nicht vorhanden.
de Martin, Rainer,
Mrowietz, Ulrich,
Wiegrebe, Wolfgang,
Jirovsky, David,
Loewe, Robert,
Pillinger, Manuela ,
Gröger, Marion,
Holnthoner, Wolfgang,
Wolff, Klaus und
Petzelbauer, Peter
(2001)
Dimethylfumarate Inhibits Tumor-Necrosis-Factor-Induced CD62E Expression in an NF-κB-Dependent Manner.
Journal of Investigative Dermatology 117 (6), S. 1363-1368.
Volltext nicht vorhanden.
Schlemmer, Richard,
Spruß, Thilo,
Bernhardt, Günther und
Schönenberger, Helmut
(2001)
Does [meso-1,2-bis(2,6-dichloro-4-hydroxy-phenyl) ethylenediamine]dichloroplatinum(II) act as an immune response modifier? IV. Inhibition of the proliferation-increasing effect of progressively growing MXT-M-3,2 breast cancer on phagocytes by the title compound.
Archiv der Pharmazie 334 (10), S. 309-317.
Volltext nicht vorhanden.
Gooch, K. J.,
Kwon, J. H.,
Blunk, T.,
Langer, R.,
Freed, L. E. und
Vunjak-Novakovic, G.
(2001)
Effects of mixing intensity on tissue-engineered cartilage.
Biotechnology and Bioengineering 72 (4), S. 402-407.
Volltext nicht vorhanden.
Gooch, K.J.,
Blunk, T.,
Courter, D.L.,
Sieminski, A.L.,
Bursac, P.M.,
Vunjak-Novakovic, G. und
Freed, L.E.
(2001)
IGF-I and Mechanical Environment Interact to Modulate Engineered Cartilage Development.
Biochemical and Biophysical Research Communications 286 (5), S. 909-915.
Volltext nicht vorhanden.
Iwasa, Kinuko,
Moriyasu, Masataka,
Yamori, Takao,
Turuo, Takashi,
Lee, Dong-Ung und
Wiegrebe, Wolfgang
(2001)
In Vitro Cytotoxicity of the Protoberberine-Type Alkaloids.
Journal of Natural Products 64 (7), S. 896-898.
Volltext nicht vorhanden.
Bischoff, Andrea,
Püttmann, Kristina,
Kötting, Annette,
Moser, Christiane,
Buschauer, Armin und
Michel, Martin C.
(2001)
Limited signal transduction repertoire of human Y_5 neuropeptide Y receptors expressed in HEC-B cells.
Peptides 22 (3), S. 387-394.
Volltext nicht vorhanden.
Jirovsky, David,
Sellmer, Andreas,
Guiswe, Pierre,
Lemr, Karel und
Wiegrebe, Wolfgang
(2001)
On the Stereochemistry of Vincetene.
Monatshefte fuer Chemie/Chemical Monthly 132 (6), S. 765-768.
Volltext nicht vorhanden.
Kees, F.,
Färber, L.,
Bucher, M.,
Mair, G.,
Mörike, K. und
Grobecker, H.
(2001)
Pharmacokinetics of therapeutic doses of tropisetron in healthy volunteers.
British Journal of Clinical Pharmacology 52 (6), S. 705-707.
Volltext nicht vorhanden.
Vogelhuber, W.,
Rutunno, P.,
Magni, E.,
Gazzaniga, A. ,
Spruss, Thilo,
Bernhardt, Günther,
Buschauer, Armin und
Goepferich, Achim
(2001)
Programmable biodegradable implants.
Journal of Controlled Release 73 (1), S. 75-88.
Volltext nicht vorhanden.
Höcherl, Klaus,
Wolf, Konrad,
Castrop, Hayo,
Ittner, Karl,
Bucher, Michael,
Kees, Frieder,
Grobecker, Horst und
Kurtz, Armin
(2001)
Renocortical expression of renin and of cyclooxygenase-2 in response to angiotensin II AT 1 receptor blockade is closely coordinated but not causally linked.
Pfl�gers Archiv European Journal of Physiology 442 (6), S. 821-827.
Volltext nicht vorhanden.
Iwasa, Kinuko,
Moriyasu, Masataka,
Tachibana, Yoko,
Kim, Hye-Sook,
Wataya, Yusuke,
Wiegrebe, Wolfgang,
Bastow, Kenneth F,
Cosentino, L.Mark,
Kozuka, Mutsuo und
Lee, Kuo-Hsiung
(2001)
Simple Isoquinoline and Benzylisoquinoline Alkaloids as Potential Antimicrobial, Antimalarial, Cytotoxic, and Anti-HIV Agents.
Bioorganic & Medicinal Chemistry 9 (11), S. 2871-2884.
Volltext nicht vorhanden.
Rostom, Sherif A. F.,
Farghaly, Ahmed M.,
Soliman, Farid S. G.,
El-Semary, Mona M.,
Elz, Sigurd und
Lehmann, Jochen
(2001)
Synthesis and 5-HT2A Antagonist Activity of Derivatives of the Novel Heterocycles Indolo[3,2-d]pyrrolo[3,2-g]azecine and Benzo[d]pyrrolo[3,2-g]azecine compared to the Benz[d]indolo[2,3-g]azecine Derivative LE 300.
Archiv der Pharmazie 334 (7), S. 241-247.
Volltext nicht vorhanden.
Mahboobi, Siavosh,
Pongratz, Herwig,
Hufsky, Harald,
Hockemeyer, Jörg,
Frieser, Markus,
Lyssenko, Alexei,
Paper, Dietrich H.,
Bürgermeister, Jutta,
Böhmer, Frank-D.,
Fiebig, Heinz-Herbert,
Burger, Angelika M.,
Baasner, Silke und
Beckers, Thomas
(2001)
Synthetic 2-Aroylindole Derivatives as a New Class of Potent Tubulin-Inhibitory, Antimitotic Agents.
Journal of Medicinal Chemistry 44 (26), S. 4535-4553.
Volltext nicht vorhanden.
Meiers, Susanne,
Kemény, Monika,
Weyand, Ulrike,
Gastpar, Robert,
von Angerer, Erwin und
Marko, Doris
(2001)
The Anthocyanidins Cyanidin and Delphinidin Are Potent Inhibitors of the Epidermal Growth-Factor Receptor.
Journal of Agricultural and Food Chemistry 49 (2), S. 958-962.
Volltext nicht vorhanden.
Sazima, M.,
Vogel, S.,
do Prado, A. Lemes,
de Oliveira, D. M.,
Franz, Gerhard und
Sazima, I.
(2001)
The sweet jelly of Combretum lanceolatum flowers (Combretaceae): a cornucopia resource for bird pollinators in the Pantanal, western Brazil.
Plant Systematics and Evolution 227, S. 195-208.
Volltext nicht vorhanden.
Zacher, J.,
Burger, K.J.,
Färber, L.,
Gräve, M.,
Abberger, H. und
Bertsch, K.
(2001)
Topisches Diclofenac Emulgel versus orales Ibuprofen in der Therapie der aktivierten Arthrose der Fingergelenke (Heberden- und/oder Bouchard-Arthrose) - Doppelblinde, kontrollierte, randomisierte Studie -.
Aktuelle Rheumatologie 26 (1), S. 7-14.
Volltext nicht vorhanden.
Diener, Hans Christoph,
Ringelstein, Erich Bernd,
von Kummer, Rüdiger,
Langohr, Hans Dieter,
Bewermeyer, Heiko,
Landgraf, Helmut,
Hennerici, Michael,
Welzel, Dieter,
Gräve, Michael,
Brom, Joachim und
Weidinger, Gottfried
(2001)
Treatment of Acute Ischemic Stroke With the Low-Molecular-Weight Heparin Certoparin.
Stroke 32 (1), S. 22-29.
Volltext nicht vorhanden.
Varga, B.,
Färber, L.,
Kohnen, R.,
Stratz, Th.,
Trocsanyi, M.,
Wild, J. und
Müller, W.
(2000)
4-wöchige Therapie mit dem 5-HT3-Rezeptor-Antagonisten Tropisetron bei der Fibromyalgie.
Aktuelle Rheumatologie 25 (01/02), S. 43-50.
Volltext nicht vorhanden.
Lee, Dong-Ung,
Kang, So-Im,
Yoon, Soo-Hong,
Budesinsky, Milos,
Kasal, Alexander,
Mayer, Klaus K. und
Wiegrebe, Wolfgang
(2000)
A New Steroidal Alkaloid from the Roots of Cynanchum caudatum.
Planta Medica 66 (5), S. 480-482.
Volltext nicht vorhanden.
Zabel, Manfred,
Breu, Josef ,
Rau, Franz,
Range, Klaus-Jürgen,
Krey, Volker,
Uffrecht, Anka und
Buschauer, Armin
(2000)
Absolute configuration of (-)-4-(3,4-dichlorophenyl)-4-(2-pyridyl)butanoic acid: essential information to determine crucial steric feature of arpromidine-type histamine H_2 receptor agonists.
Acta Crystallographica Section C 56, S. 250-251.
Volltext nicht vorhanden.
Lucke, Andrea,
Teßmar, Jörg ,
Schnell, Edith,
Schmeer, Georg und
Göpferich, Achim
(2000)
Biodegradable poly(d,l-lactic acid)-poly(ethylene glycol)-monomethyl ether diblock copolymers: structures and surface properties relevant to their use as biomaterials.
Biomaterials 21 (23), S. 2361-2370.
Volltext nicht vorhanden.
Schlemmer, Richard,
Spruß, Thilo,
Bernhardt, Günther und
Schönenberger, Helmut
(2000)
Does [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]- dichloro-platinum(II) act as an immune response modifier? Part III: Progressively growing MXT-M-3,2 breast cancer stimulates the proliferation of phagocytes in B6D2F1 mice.
Archiv der Pharmazie 333 (12), S. 404-414.
Volltext nicht vorhanden.
Schlemmer, Richard,
Spruß, Thilo,
Bernhardt, Günther und
Schönenberger, Helmut
(2000)
Does [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]- dichloroplatinum(II) act on the hormone-sensitive, murine breast cancer as a biological response modifier? Part 1: The MXT-M-3.2 breast cancer stimulates the growth of an identical second graft; [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]dichloroplat inum (II) inhibits this process.
Archiv der Pharmazie 333 (2-3), S. 69-71.
Volltext nicht vorhanden.
Schlemmer, Richard,
Spruß, Thilo,
Bernhardt, Günther und
Schönenberger, Helmut
(2000)
Does [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]- dichloroplatinum(II) act on the hormone-sensitive, murine breast cancer as a biological response modifier? Part II. Studies on the influence of [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine] dichloroplatinum(II) on the specific immune defense in MXT-M-3,2 breast cancer bearing mice.
Archiv der Pharmazie 333 (12), S. 397-403.
Volltext nicht vorhanden.
Shafi, Shahida,
Stepanova, Irina P,
Fitzsimmons, C,
Bowyer, D.E,
Welzel, D und
Born, G.V.R
(2000)
Effects of reserpine on expression of the LDL receptor in liver and on plasma and tissue lipids, low density lipoprotein and fibrinogen in rabbits in vivo.
Atherosclerosis 149 (2), S. 267-275.
Volltext nicht vorhanden.
Schönberger, Johann,
Bauer, Johann,
Spruß, Thilo,
Weber, Gerhard,
Chahoud, Ibrahim,
Eilles, Christoph und
Grimm, Daniela
(2000)
Establishment and characterization of the follicular thyroid carcinoma cell line ML-1.
Journal of Molecular Medicine 78 (2), S. 102-110.
Volltext nicht vorhanden.
Kees, ,
Holstege, ,
Ittner, ,
Zimmermann, ,
Lock, ,
Schölmerich, und
Grobecker,
(2000)
Pharmacokinetic interaction between proton pump inhibitors and roxithromycin in volunteers.
Alimentary Pharmacology & Therapeutics 14 (4), S. 407-412.
Volltext nicht vorhanden.
Aiglstorfer, Iris,
Hendrich, Ingo,
Moser, Christiane,
Bernhardt, Günther,
Dove, Stefan und
Buschauer, Armin
(2000)
Structure-Activity Relationships of Neuropeptide Y Y_1 Receptor Antagonists Related to BIBP 3226,.
Bioorganic & Medicinal Chemistry Letters 10 (14), S. 1597-1600.
Volltext nicht vorhanden.
Mahboobi, Siavosh,
Dechant, Irene,
Reindl, Hans,
Pongratz, Herwig,
Popp, Alfred und
Schollmeyer, Dieter
(2000)
Synthesis of bis(indolylmaleimide) macrocycles.
Journal of Heterocyclic Chemistry 37 (2), S. 307-329.
Volltext nicht vorhanden.
Mahboobi, Siavosh,
Eluwa, Stella,
Koller, Markus,
Popp, Alfred und
Schollmeyer, Dieter
(2000)
Synthesis of pyrrolo[3′,4′:2,3]azepino[4,5,6‐cd]indole‐8,10‐diones.
Journal of Heterocyclic Chemistry 37 (5), S. 1177-1185.
Volltext nicht vorhanden.
Ittner, K.P.,
Zimmermann, M.,
Bucher, M.,
Gessele, W.,
Kees, F.,
Krämer, B.K. und
Grobecker, H.F.
(2000)
The effect of urapidil and ramipril on hyperglycemia in streptozotocin diabetic rats.
Naunyn-Schmiedeberg's Archives of Pharmacology 361 (1), S. 92-97.
Volltext nicht vorhanden.
Hagelüken, A.,
Grünbaum, L.,
Nürnberg, B.,
Harhammer, R.,
Schunack, W. und
Seifert, Roland
(1994)
Lipophilic beta-adrenoceptor antagonists and local anesthetics are effective direct activators of G-proteins.
Biochemical pharmacology 47 (10), S. 1789-1795.
Klinker, J. F.,
Hagelüken, A.,
Grünbaum, L.,
Heilmann, I.,
Nürnberg, B.,
Harhammer, R.,
Offermanns, S.,
Schwaner, I.,
Ervens, J.,
Wenzel-Seifert, K.,
Müller, T. und
Seifert, Roland
(1994)
Mastoparan may activate GTP hydrolysis by Gi-proteins in HL-60 membranes indirectly through interaction with nucleoside diphosphate kinase.
The Biochemical journal 304 ( Pt 2, S. 377-383.
Seifert, Roland,
Hagelüken, A.,
Höer, A.,
Höer, D.,
Grünbaum, L.,
Offermanns, S.,
Schwaner, I.,
Zingel, V.,
Schunack, W. und
Schultz, Günter
(1994)
The H1 receptor agonist 2-(3-chlorophenyl)histamine activates Gi proteins in HL-60 cells through a mechanism that is independent of known histamine receptor subtypes.
Molecular Pharmacology 45 (4), S. 578-586.
Tsang, K. W.,
Roberts, P.,
Read, R. C.,
Kees, Frieder,
Wilson, R. und
Cole, P. J.
(1994)
The concentrations of clarithromycin and its 14-hydroxy metabolite in sputum of patients with bronchiectasis following single dose oral administration.
The Journal of antimicrobial chemotherapy 33 (2), S. 289-297.
Klinker, J. F.,
Höer, A.,
Schwaner, I.,
Offermanns, S.,
Wenzel-Seifert, Katharina und
Seifert, Roland
(1993)
Lipopeptides activate Gi-proteins in dibutyryl cyclic AMP-differentiated HL-60 cells.
The Biochemical journaL 296 ( Pt 1, S. 245-251.
Klinz, F. J.,
Seifert, Roland,
Schwaner, I.,
Gausepohl, H.,
Frank, R. und
Schultz, Günter
(1992)
Generation of specific antibodies against the rap1A, rap1B and rap2 small GTP-binding proteins. Analysis of rap and ras proteins in membranes from mammalian cells.
European journal of biochemistry 207 (1), S. 207-213.
Seifert, Roland,
Serke, S.,
Huhn, D.,
Bessler, W. G.,
Hauschildt, S.,
Metzger, J.,
Wismüller, K. H. und
Jung, G.
(1992)
Incomplete functional differentiation of HL-60 leukemic cells by synthetic lipopeptides. Partial inhibition by pertussis toxin of enhanced superoxide formation.
European journal of biochemistry / FEBS 203 (1-2), S. 143-151.
Offermanns, S.,
Seifert, Roland,
Metzger, J. W.,
Jung, G.,
Lieberknecht, A.,
Schmidt, U. und
Schultz, Günter
(1992)
Lipopeptides are effective stimulators of tyrosine phosphorylation in human myeloid cells.
Biochemical Journal 282 ( Pt 2, S. 551-7.
Seifert, Roland,
Schultz, Günter,
Richter-Freund, M.,
Metzger, J.,
Wiesmüller, K. H.,
Jung, G.,
Bessler, W. G. und
Hauschildt, S.
(1990)
Activation of superoxide formation and lysozyme release in human neutrophils by the synthetic lipopeptide Pam3Cys-Ser-(Lys)4. Involvement of guanine-nucleotide-binding proteins and synergism with chemotactic peptides.
The Biochemical journal 267 (3), S. 795-802.
Naber, K. G.,
Sörgel, F.,
Kees, Frieder K.,
Schumacher, H.,
Sigl, G.,
Zürcher, J. und
Berger, S.
(1989)
Enoxacin-Konzentrationen in der Samenflüssigkeit, im Prostatasekret und im Prostataadenomgewebe nach oraler Gabe oder intravenöser Infusion [Enoxacin concentration in seminal fluid, in prostate secretions and in prostatic adenoma tissue following oral administration or intravenous infusion].
Infection 17 Suppl 1, S30-S66.
Rudolph, U.,
Koesling, D.,
Hinsch, K. D.,
Seifert, Roland,
Bigalke, M.,
Schultz, Günter und
Rosenthal, W.
(1989)
G-protein alpha-subunits in cytosolic and membranous fractions of human neutrophils.
Molecular and cellular endocrinology 63 (1-2), S. 143-153.
Naber, K. G.,
Sörgel, F.,
Kees, Frieder K.,
Jaehde, U. und
Schumacher, H.
(1989)
Pharmacokinetics of ciprofloxacin in young (healthy volunteers) and elderly patients, and concentrations in prostatic fluid, seminal fluid, and prostatic adenoma tissue following intravenous administration.
The American journal of medicine 87 (5supl1), S57-S59.
Naber, K. G.,
Sörgel, F.,
Kees, Frieder K.,
Schumacher, H.,
Metz, R. und
Grobecker, H.
(1988)
In-vitro activity of fleroxacin against isolates causing complicated urinary tract infections and concentrations in seminal and prostatic fluid and in prostatic adenoma tissue.
The Journal of antimicrobial chemotherapy 22 Suppl D, S. 199-207.
Seifert, Roland,
Rosenthal, W.,
Schultz, Günter,
Wieland, T.,
Gierschick, P. und
Jakobs, K. H.
(1988)
The role of nucleoside-diphosphate kinase reactions in G protein activation of NADPH oxidase by guanine and adenine nucleotides.
European journal of biochemistry / FEBS 175 (1), S. 51-55.
Naber, K.,
Kees, Frieder K.,
Denk, K.,
Bauernfeind, A. und
Grobecker, H.
(1987)
Carumonam versus ceftazidime: in vitro activity, pharmacokinetics in elderly patients, safety and therapeutic efficacy in the treatment of complicated urinary tract infections.
Chemioterapia 6 (2 Supl), S. 517-518.
Volltext nicht vorhanden.
Grobecker, H.,
Kees, Frieder K.,
Linden, M.,
Schrader, E. und
Welte, S.
(1987)
Untersuchungen zur Bioverfügbarkeit von Midodrin und 2,5- Dimethoxyphenyl-ß-aminoethanol-hydrochlorid [The bioavailability of midodrin and alpha-2,5-dimethoxyphenyl-beta-aminoethanol hydrochloride].
Arzneimittel-Forschung 37 (4), S. 447-450.
Naber, K. G.,
Dette, G. A.,
Kees, Frieder K.,
Knothe, H. und
Grobecker, H.
(1986)
Pharmacokinetics, in-vitro activity, therapeutic efficacy and clinical safety of aztreonam vs. cefotaxime in the treatment of complicated urinary tract infections.
The Journal of antimicrobial chemotherapy 17 (4), S. 517-527.
Grobecker, H.,
Gessler, I.,
Delius, W.,
Dominiak, P. und
Kees, Frieder K.
(1985)
Effect of ketanserin on hemodynamics, plasma-catecholamine concentrations, and serotonin uptake by platelets in volunteers and patients with congestive heart failure.
Journal of cardiovascular pharmacology 7, Suppl 7, S102-S104.
Kees, Frieder K.,
Naber, K. G.,
Bartoschik-Wich, B.,
Stockmann, P.,
Meyer, G. P. und
Grobecker, H.
(1985)
High-performance liquid chromatography analysis of mezlocillin, piperacillin, their degradation products, and of ioxitalamic acid in plasma and urine of healthy volunteers.
Arzneimittel-Forschung 35 (7), S. 1099-1104.
Kees, Frieder K.,
Strehl, E.,
Dominiak, P.,
Grobecker, H.,
Seeger, K.,
Seidel, G.,
Neuhaus, B. und
Safrany, L.
(1983)
Cefotaxime and desacetyl cefotaxime in human bile.
Infection 11 (2), S. 118-120.
Kees, Frieder K.,
Strehl, E.,
Seeger, K.,
Seidel, G.,
Dominiak, P. und
Grobecker, H.
(1981)
Comparative determination of cefotaxime and desacetyl cefotaxime in serum and bile by bioassay and high-performance liquid chromatography.
Arzneimittel-Forschung 31 (2), S. 362-365.
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