Dewey Decimal Classification

Dewey Decimal Classification (DDC) (579)
- 600 Technology (579)
  - 615 Pharmacy (579)

Number of items at this level: 579.

Höring, Carina

(2023) Split-Luciferase Complementation and Molecular Dynamics Studies for the Mini-G Protein-Based Functional Characterization of GPCRs. PhD, Universität Regensburg.

Geiben, Ann-Kathrin Christine Maria (2023) Analyse von Sedierung als unerwünschte Arzneimittelwirkung und Entwicklung eines Risikoscores für die Gerontopsychiatrie. PhD, Universität Regensburg.

Greppmair, Sebastian, Brinkmann, Alexander, Roehr, Anka, Frey, Otto, Hagel, Stefan, Dorn, Christoph

, Marsot, Amélie, El-Haffaf, Ibrahim, Zoller, Michael, Saller, Thomas, Zander, Johannes, Schatz, Lea Marie, Scharf, Christina, Briegel, Josef, Minichmayr, Iris K., Wicha, Sebastian G. and Liebchen, Uwe (2023) Towards model-informed precision dosing of piperacillin: multicenter systematic external evaluation of pharmacokinetic models in critically ill adults with a focus on Bayesian forecasting. Intensive Care Medicine.

Ziegler, Christian (2023) Development of Injectable Anhydrous Hydrogels for the Controlled Release of Therapeutic Proteins. PhD, Universität Regensburg.

Bohley, Marilena

, Dillinger, Andrea E., Braunger, Barbara M., Tamm, Ernst R. and Goepferich, Achim

(2023) Intravenous injection of cyclosporin A loaded lipid nanocapsules fights inflammation and immune system activation in a mouse model of diabetic retinopathy. Drug Delivery and Translational Research.

Chen, Zhendong, Taubert, Max, Chen, Chunli, Dokos, Charalambos, Fuhr, Uwe, Weig, Thomas, Zoller, Michael, Heck, Suzette, Dimitriadis, Konstantinos, Terpolilli, Nicole, Kinast, Christina, Scharf, Christina, Lier, Constantin, Dorn, Christoph

and Liebchen, Uwe (2023) Plasma and Cerebrospinal Fluid Population Pharmacokinetics of Vancomycin in Patients with External Ventricular Drain. Antimicrobial Agents and Chemotherapy. Fulltext not available.

Wirth, Ulrike, Erl, Julia, Azzam, Saphia, Hoering, Carina, Skiba, Michael, Singh, Ritu, Hochmuth, Kathrin, Keller, Max

, Wegener, Joachim

and König, Burkhard

(2023) Monitoring the Reversibility of GPCR Signaling by Combining Photochromic Ligands with Label-free Impedance Analysis. Angewandte Chemie International Edition, e202215547.

Grätz, Lukas (2023) Luminescence-based methods for the investigation of ligand binding and GRK2 recruitment to GPCRs. PhD, Universität Regensburg.

Hoffelner, Beate Sandra, Andreev, Stanislav

, Plank, Nicole and Koch, Pierre

(2023) Photocaging of Pyridinylimidazole-Based Covalent JNK3 Inhibitors Affords Spatiotemporal Control of the Binding Affinity in Live Cells. Pharmaceuticals 16 (2), p. 264.

Prüschenk, Sally (2023) Molekulare und physiologische Funktion von IRAG2 in Thrombozyten und im Pankreas. PhD, Universität Regensburg.

Zimmer, Oliver

and Goepferich, Achim

(2022) How clathrin-coated pits control nanoparticle avidity for cells. Nanoscale Horizons, (Advance Art.).

Sanz-Codina, Maria, Wicha, Sebastian G, Wulkersdorfer, Beatrix, Al Jalali, Valentin, Van Os, Wisse, Vossen, Matthias G, Bauer, Martin, Lackner, Edith, Dorn, Christoph

and Zeitlinger, Markus (2022) Comparison of ultrafiltration and microdialysis for ceftriaxone protein-binding determination. Journal of Antimicrobial Chemotherapy. Fulltext not available.

Jorda, Anselm

, Wulkersdorfer, Beatrix, Schoergenhofer, Christian, Matzneller, Peter, Jalali, Valentin A. L., Bauer, Martin, Wölfl‐Duchek, Michael, Lackner, Edith, Dorn, Christoph

, Jilma, Bernd and Zeitlinger, Markus

(2022) Effect of the human endotoxin challenge on tedizolid tissue penetration. British Journal of Clinical Pharmacology, (accept.art.). Fulltext not available.

Forster, Lisa

(2022) Development of radioligand binding and functional assays for the characterization of dopamine D2-like receptor ligands. PhD, Universität Regensburg.

Bohley, Marilena (2022) Targeted Lipid Nanoparticles for Retinal Drug Delivery. PhD, Universität Regensburg.

Bohley, Marilena, Dillinger, Andrea E., Schweda, Frank, Ohlmann, Andreas, Braunger, Barbara M., Tamm, Ernst R. and Goepferich, Achim

(2022) A single intravenous injection of cyclosporin A–loaded lipid nanocapsules prevents retinopathy of prematurity. Science Advances 8 (38).

Ziegler, Christian, Graf, Moritz, Nagaoka, Makoto and Goepferich, Achim

(2022) Investigation of the Impact of Hydrolytically Cleavable Groups on the Stability of Poly(ethylene glycol) Based Hydrogels Cross-Linked via the Inverse Electron Demand Diels-Alder (iEDDA) Reaction. Macromolecular Bioscience 22 (12), p. 2200226.

Heinl, Elena-Sofia, Lorenz, Sebastian, Schmidt, Barbara

, Laqtom, Nouf Nasser M., Mazzulli, Joseph R., Francelle, Laetitia, Yu, Timothy W., Greenberg, Benjamin, Storch, Stephan, Tegtmeier, Ines, Othmen, Helga, Maurer, Katja, Steinfurth, Malin, Witzgall, Ralph

, Milenkovic, Vladimir M.

, Wetzel, Christian H.

and Reichold, Markus (2022) CLN7/MFSD8 may be an important factor for SARS-CoV-2 cell entry. iScience 25 (10), p. 105082.

Andreev, Stanislav

, Plank, Nicole, Schollmeyer, Dieter and Koch, Pierre

(2022) (S)-3-(3-((7-Ethynyl-9H-pyrimido[4,5-b]indol-4-yl)amino)piperidin-1-yl)propanenitrile. Molbank 2022 (3), M1437.

Dorn, Christoph

, Petroff, David, Kratzer, Alexander, Kees, Frieder

, Kloft, Charlotte, Zeitlinger, Markus, Wrigge, Hermann and Simon, Philipp (2022) Tigecycline Soft Tissue Penetration in Obese and Non-obese Surgical Patients Determined by Using In Vivo Microdialysis. European Journal of Drug Metabolism and Pharmacokinetics 47, pp. 749-755.

Meurer, Florian

, Dolomanov, Oleg V., Hennig, Christoph, Peyerimhoff, Norbert, Kleemiss, Florian

, Puschmann, Horst and Bodensteiner, Michael

(2022) Refinement of anomalous dispersion correction parameters in single-crystal structure determinations. IUCrJ / International Union of Crystallography 9 (5), pp. 604-609.

Schlossmann, Jens

(2022) Editorial of the Special Issue: cGMP-Signaling in Cells and Tissues: Molecular, Functional and Pharmacological Aspects. International Journal of Molecular Sciences 23 (12), p. 6482.

Forster, Lisa and Pockes, Steffen

(2022) Investigating the ligand agonism and antagonism at the D2long receptor by dynamic mass redistribution. Scientific Reports 12 (1).

Braun, Daniel Simon (2022) Asymmetrisches Dimethylarginin bei psychiatrischen Erkrankungen. PhD, Universität Regensburg.

Bresinsky, Merlin, Strasser, Jessica M., Hubmann, Alexander, Vallaster, Bernadette, McCue, William M., Fuller, Jessica, Singh, Gurpreet, Nelson, Kathryn M., Cuellar, Matthew E., Finzel, Barry C., Ashe, Karen H., Walters, Michael A. and Pockes, Steffen

(2022) Characterization of caspase‐2 inhibitors based on specific sites of caspase‐2‐mediated proteolysis. Archiv der Pharmazie 355 (9), p. 2200095.

Majer, Michael (2022) Splenomegalie assoziierte Anämie in Folge der Defizienz des PKGIβ/IRAG1-Signalweges. PhD, Universität Regensburg.

Endres, Katharina Walburga Maria

(2022) Wirkstoffkonzentrationsbestimmungen zur Therapieleitung der medikamentösen Behandlung kardiovaskulärer Erkrankungen bei psychiatrischen Patienten. PhD, Universität Regensburg.

Stahl, Monika, Holzinger, Jonas M., Bülow, Sigrid

and Goepferich, Achim

(2022) Enzyme-triggered antigen release enhances cross presentation by dendritic cells. Nanomedicine: Nanotechnology, Biology, and Medicine 42, p. 102545. Fulltext not available.

Jorda, Anselm

, Wulkersdorfer, Beatrix, Schörgenhofer, Christian, Matzneller, Peter

, Al Jalali, Valentin

, Bauer, Martin, Wölf-Duchek, Michael, Lackner, Edith, Dorn, Christoph

, Jilma, Bernd

and Zeitlinger, Markus (2022) Influence of tedizolid on the cytokine response to the endotoxin challenge in healthy volunteers: a cross-over trial. Journal of Antimicrobial Chemotherapy. Fulltext not available.

Konieczny, Adam (2022) Design, Synthesis and Pharmacological Characterization of Oligopeptidic and Non-Peptidic Neuropeptide Y Y4 Receptor Ligands. PhD, Universität Regensburg.

Ousingsawat, Jiraporn

, Centeio, Raquel, Cabrita, Inês

, Talbi, Khaoula, Zimmer, Oliver

, Graf, Moritz, Göpferich, Achim

, Schreiber, Rainer

and Kunzelmann, Karl

(2022) Airway Delivery of Hydrogel-Encapsulated Niclosamide for the Treatment of Inflammatory Airway Disease. International Journal of Molecular Sciences 23 (3), p. 1085.

Rösch, Gundula, Muschter, Dominique

, Taheri, Shahed, El Bagdadi, Karima, Dorn, Christoph

, Meurer, Andrea, Zaucke, Frank, Schilling, Arndt F., Grässel, Susanne

, Straub, Rainer H.

and Jenei-Lanzl, Zsuzsa (2022) β2-Adrenoceptor Deficiency Results in Increased Calcified Cartilage Thickness and Subchondral Bone Remodeling in Murine Experimental Osteoarthritis. Frontiers in Immunology 12.

Peterhoff, David

, Thalhauser, Stefanie, Neckermann, Patrick, Barbey, Clara, Straub, Kristina

, Nazet, Julian, Merkl, Rainer

, Längst, Gernot

, Breunig, Miriam

and Wagner, Ralf

(2022) Multivalent display of engineered HIV-1 envelope trimers on silica nanoparticles for targeting and in vitro activation of germline VRC01 B cells. European Journal of Pharmaceutics and Biopharmaceutics 181, pp. 88-101. Fulltext not available.

Mietzner, Raphael

, Pawlak, Ramona, Tamm, Ernst R.

, Goepferich, Achim

, Fuchshofer, Rudolf

and Breunig, Miriam

(2021) Angiopoietin-1 Mimetic Nanoparticles for Restoring the Function of Endothelial Cells as Potential Therapeutic for Glaucoma. Pharmaceuticals 15 (1), p. 18.

Harloff, Manuela (2021) Der sGC-Aktivator Cinaciguat als Therapieoption der diabetischen Nephropathie und Untersuchung von glukoseinduzierten molekularen Mechanismen in Mesangialzellen. PhD, Universität Regensburg.

Prüschenk, Sally, Majer, Michael

, Schreiber, Rainer

and Schlossmann, Jens

(2021) IRAG2 Interacts with IP3-Receptor Types 1, 2, and 3 and Regulates Intracellular Ca2+ in Murine Pancreatic Acinar Cells. International Journal of Molecular Sciences 22 (24), p. 13409.

Busse, David, Simon, Philipp, Schmitt, Lisa, Petroff, David, Dorn, Christoph

, Dietrich, Arne, Zeitlinger, Markus, Huisinga, Wilhelm, Michelet, Robin, Wrigge, Hermann and Kloft, Charlotte (2021) Comparative Plasma and Interstitial Tissue Fluid Pharmacokinetics of Meropenem Demonstrate the Need for Increasing Dose and Infusion Duration in Obese and Non-obese Patients. Clinical Pharmacokinetics.

Dorn, Christoph

(2021) 3.3. Informationen über Arzneimittel. In: Sax, Michael, (ed.) Pharmazie für die Praxis : Lehrbuch für Pharmazeuten im Praktikum : Handbuch für die Apotheke. Deutscher Apotheker Verlag, Stuttgart, pp. 152-173. ISBN 978-3-7692-7010-5. Fulltext not available.

Rösch, Gundula, El Bagdadi, Karima, Muschter, Dominique

, Taheri, Shahed, Dorn, Christoph

, Meurer, Andrea, Straub, Rainer H.

, Zaucke, Frank

, Schilling, Arndt F., Grässel, Susanne

and Jenei-Lanzl, Zsuzsa (2021) Sympathectomy aggravates subchondral bone changes during osteoarthritis progression in mice without affecting cartilage degeneration or synovial inflammation. Osteoarthritis and Cartilage 30 (3), pp. 461-474. Fulltext not available.

Lawrowska, Alexandra (2021) Nanoparticles for drug delivery to ocular neovascularizations. PhD, Universität Regensburg.

Kuck, Katrin (2021) Isolierung von terpenoiden Sekundärstoffen aus C. myrrha und pharmakologische Testung in einem ICAM-1 in vitro Modell. PhD, Universität Regensburg.

Bartole, Edith

(2021) Design, Synthesis and Characterization of Molecular Tools for the Histamine H3 and H4 Receptors – In Particular Radio- and Fluorescent Ligands. PhD, Universität Regensburg.

Busse, David, Borghardt, Jens Markus, Petroff, David, Pevzner, Alice, Dorn, Christoph

, El‐Najjar, Nahed, Huisinga, Wilhelm, Wrigge, Hermann, Simon, Philipp and Kloft, Charlotte (2021) EVALUATING PREDICTION METHODS FOR GLOMERULAR FILTRATION TO OPTIMISE DRUG DOSES IN OBESE AND NON‐OBESE PATIENTS. British Journal of Clinical Pharmacology. Fulltext not available.

Busse, David, Simon, Philipp, Petroff, David, Dorn, Christoph

, Schmitt, Lisa, Bindellini, Davide, Kratzer, Alexander, Dietrich, Arne, Zeitlinger, Markus, Huisinga, Wilhelm, Michelet, Robin, Wrigge, Hermann and Kloft, Charlotte (2021) Similar Piperacillin/Tazobactam Target Attainment in Obese versus Nonobese Patients despite Differences in Interstitial Tissue Fluid Pharmacokinetics. Pharmaceutics 13 (9), p. 1380.

Buschmann, Jonas (2021) Synthesis and pharmacological characterization of argininamide-type neuropeptide Y (NPY) Y1 and Y2 receptor antagonists and synthesis of non-peptide potential NPY Y4 receptor ligands. PhD, Universität Regensburg.

Peterhoff, David

, Thalhauser, Stefanie, Sobczak, Jan M., Mohsen, Mona O., Voigt, Christoph, Seifert, Nicole

, Neckermann, Patrick, Hauser, Alexandra

, Ding, Song, Sattentau, Quentin, Bachmann, Martin F.

, Breunig, Miriam

and Wagner, Ralf (2021) Augmenting the Immune Response against a Stabilized HIV-1 Clade C Envelope Trimer by Silica Nanoparticle Delivery. Vaccines 9 (642), pp. 1-24.

Maslanka Figueroa, Sara

(2021) Heteromultivalent Virus-mimetic Nanoparticles for Specific Mesangial Cell Targeting. PhD, Universität Regensburg.

Schlossmann, Jens

, Majer, Michael and Prueschenk, Sally (2021) Loss of PKGIβ/IRAG1 Signaling Causes Anemia-Associated Splenomegaly. International Journal of Molecular Sciences 22 (5458), pp. 1-20.

Weinhart, Corinna G.

(2021) Synthesis and pharmacological characterization of
dibenzodiazepinone-type muscarinic M2-receptor
antagonists conjugated to fluorescent dyes or
small peptides. PhD, Universität Regensburg.

Maslanka-Figueroa, Sara

, Fleischmann, Daniel and Göpferich, Achim

(2021) Biomedical nanoparticle design: What we can learn from viruses. Journal of Controlled Release 329, pp. 552-569. Fulltext not available.

Rosier, Niklas, Grätz, Lukas, Schihada, Hannes, Möller, Jan, Işbilir, Ali, Humphrys, Laura J., Nagl, Martin, Seibel, Ulla, Lohse, Martin J. and Pockes, Steffen

(2021) A Versatile Sub-Nanomolar Fluorescent Ligand Enables NanoBRET Binding Studies and Single-Molecule Microscopy at the Histamine H3 Receptor. Journal of Medicinal Chemistry 64 (15), pp. 11695-11708. Fulltext not available.

Ziegler, Christian, Graf, Moritz, Beck, Sebastian and Göpferich, Achim

(2021) A novel anhydrous preparation of PEG hydrogels enables high drug loading with biologics for controlled release applications. European Polymer Journal (147), p. 110286. Fulltext not available.

Tropmann, Katharina, Bresinsky, Merlin, Forster, Lisa, Mönnich, Denise, Buschauer, Armin

, Wittmann, Hans-Joachim, Hübner, Harald, Gmeiner, Peter, Pockes, Steffen

and Strasser, Andrea

(2021) Abolishing Dopamine D2long/D3 Receptor Affinity of Subtype-Selective Carbamoylguanidine-Type Histamine H2 Receptor Agonists. Journal of Medicinal Chemistry 64 (12), pp. 8684-8709. Fulltext not available.

Endres, Katharina, Schiller, Ernst and Haen, Ekkehard (2021) Antihypertensiva in der Psychiatrie. Der Nervenarzt 92, pp. 487-792.

Groner, Jonas, Göpferich, Achim

and Breunig, Miriam

(2021) Atherosclerosis: Conventional intake of cardiovascular drugs versus delivery using nanotechnology - A new chance for causative therapy? Journal of Controlled Release 333, pp. 539-559. Fulltext not available.

Gergs, Ulrich, Büxel, Maren L., Bresinsky, Merlin, Kirchhefer, Uwe, Fehse, Charlotte, Höring, Carina, Hofmann, Britt, Marušáková, Margaréta, Čináková, Aneta, Schwarz, Rebecca, Pockes, Steffen

and Neumann, Joachim (2021) Cardiac Effects of Novel Histamine H2 Receptor Agonists. Journal of Pharmacology and Experimental Therapeutics 379 (3), pp. 223-234. Fulltext not available.

Dorn, Christoph

, Petroff, David, Stoelzel, Melanie, Kees, Martin G.

, Kratzer, Alexander, Dietrich, Arne, Kloft, Charlotte, Zeitlinger, Markus, Kees, Frieder

, Wrigge, Hermann and Simon, Philipp (2021) Perioperative administration of cefazolin and metronidazole in obese and non-obese patients: a pharmacokinetic study in plasma and interstitial fluid. Journal of Antimicrobial Chemotherapy. Fulltext not available.

Biselli, Sabrina, Bresinsky, Merlin, Tropmann, Katharina

, Forster, Lisa, Honisch, Claudia, Buschauer, Armin

, Bernhardt, Günther

and Pockes, Steffen

(2021) Pharmacological characterization of a new series of carbamoylguanidines reveals potent agonism at the H2R and D3R. European Journal of Medicinal Chemistry 214, p. 113190. Fulltext not available.

Al Jalali, V.

, Wölfl-Duchek, M., Taubert, M.

, Matzneller, P.

, Lackner, E., Dorn, Christoph

, Kratzer, A., Wulkersdorfer, B., Österreicher, Z and Zeitlinger, Markus (2021) Plasma and soft tissue pharmacokinetics of ceftolozane/tazobactam in healthy volunteers after single and multiple intravenous infusion: a microdialysis study. Journal of Antimicrobial Chemotherapy. Fulltext not available.

Wulkersdorfer, Beatrix, Wicha, Sebastian G., Kurdina, Elizaveta, Carrion Carrera, Stephan F., Matzneller, Peter, Al Jalali, Valentin, Vossen, Matthias G., Riesenhuber, Sonja, Lackner, Edith, Dorn, Christoph

and Zeitlinger, Markus (2021) Protein binding of clindamycin in vivo by means of intravascular microdialysis in healthy volunteers. Journal of Antimicrobial Chemotherapy. Fulltext not available.

Szczepańska, Katarzyna, Pockes, Steffen

, Podlewska, Sabina, Höring, Carina

, Mika, Kamil, Latacz, Gniewomir, Bednarski, Marek, Siwek, Agata, Karcz, Tadeusz, Nagl, Martin, Bresinsky, Merlin, Mönnich, Denise, Seibel, Ulla, Kuder, Kamil J., Kotańska, Magdalena, Stark, Holger, Elz, Sigurd

and Kieć-Kononowicz, Katarzyna (2021) Structural modifications in the distal, regulatory region of histamine H3 receptor antagonists leading to the identification of a potent anti-obesity agent. European Journal of Medicinal Chemistry 213, p. 113041. Fulltext not available.

Kuck, Katrin, Jürgenliemk, Guido, Lipowicz, Bartosz and Heilmann, Jörg (2020) Sesquiterpenes from Myrrh and Their ICAM-1 Inhibitory Activity In Vitro. Molecules 26 (1), p. 42.

Höring, Carina

, Seibel, Ulla

, Tropmann, Katharina, Grätz, Lukas

, Mönnich, Denise

, Pitzl, Sebastian, Bernhardt, Günther

, Pockes, Steffen

and Strasser, Andrea (2020) A Dynamic, Split-Luciferase-Based Mini-G Protein Sensor to Functionally Characterize Ligands at All Four Histamine Receptor Subtypes. International Journal of Molecular Sciences 21 (22), p. 8440.

Simeth, Nadja Anita

, Kinateder, Thomas

, Rajendran, Chitra, Nazet, Julian, Merkl, Rainer

, Sterner, Reinhard

, König, Burkhard

and Kneuttinger, Andrea C.

(2020) Towards Photochromic Azobenzene‐Based Inhibitors for Tryptophan Synthase. Chemistry—A European Journal 27, pp. 2439-2451.

Bahr, Lisa-Marie (2020) Investigating the role of the central and the peripheral
benzodiazepine receptor on stress and anxiety related
parameters. PhD, Universität Regensburg.

Naporra, Franziska Gertraud (2020) Synthese und pharmakologische Charakterisierung neuer trizyklischer Liganden am Histamin-H1/H4-Rezeptor. PhD, Universität Regensburg.

Grätz, Lukas, Tropmann, Katharina, Bresinsky, Merlin, Müller, Christoph, Bernhardt, Günther

and Pockes, Steffen (2020) NanoBRET binding assay for histamine H2 receptor ligands using live recombinant HEK293T cells. Scientific Reports 10, p. 13288.

Schwarz, Mirjam (2020) Erstellung eines Hypotonie-Risikoscores und Validierung anhand einer retrospektiven Anwendungsbeobachtung an geriatrischen Patienten. PhD, Universität Regensburg.

Mietzner, Raphael

, Kade, Christian, Froemel, Franziska, Pauly, Diana, Stamer, W. Daniel, Ohlmann, Andreas, Wegener, Joachim, Fuchshofer, Rudolf and Breunig, Miriam

(2020) Fasudil Loaded PLGA Microspheres as Potential Intravitreal Depot Formulation for Glaucoma Therapy. Pharmaceutics 12 (8), p. 706.

Littmann, Timo (2020) Towards a method for the simultaneous quantification of Gαq activation β-arrestin2 recruitment. PhD, Universität Regensburg.

Bartole, Edith, Grätz, Lukas, Littmann, Timo, Wifling, David

, Seibel, Ulla, Buschauer, Armin

and Bernhardt, Günther (2020) UR-DEBa242: A Py-5-Labeled Fluorescent Multipurpose Probe for Investigations on the Histamine H3 and H4 Receptors. Journal of Medicinal Chemistry 63 (10), pp. 5297-5311. Fulltext not available.

Maslanka Figueroa, Sara

, Fleischmann, Daniel, Beck, Sebastian, Tauber, Philipp, Witzgall, Ralph, Schweda, Frank and Goepferich, Achim (2020) Nanoparticles Mimicking Viral Cell Recognition Strategies Are Superior Transporters into Mesangial Cells. Advanced Science 7 (11), p. 1903204.

Guter, Michaela (2020) Layer-by-layer nanoparticles for glaucoma therapy. PhD, Universität Regensburg.

Dorn, Christoph

, Schießer, Selina, Wulkersdorfer, Beatrix, Hitzenbichler, Florian, Kees, Martin G.

and Zeitlinger, Markus (2020) Determination of free clindamycin, flucloxacillin or tedizolid in plasma: Keep attention to physiological conditions when using ultrafiltration. Biomedical Chromatography 34, e4820.

Goepferich, Achim

, Maslanka-Figueroa, Sara, Fleischmann, Daniel and Beck, Sebastian (2020) Thermodynamic, Spatial and Methodological Considerations for the Manufacturing of Therapeutic Polymer Nanoparticles. Pharmaceutical Research 37 (59).

Veser, Anika (2020) Multivalently binding antagonists for the neurokinin-1 receptor. PhD, Universität Regensburg.

Abstiens, Kathrin

(2020) Heteromultivalent Nanoparticles for Selective Targeting of Renal Cells. PhD, Universität Regensburg.

Koehler, Katrin, Hmida, Dorra, Schlossmann, Jens, Landgraf, Dana, Reisch, Nicole, Schuelke, Markus and Huebner, Angela (2020) Homozygous mutation in murine retrovirus integration site 1 gene associated with a non‐syndromic form of isolated familial achalasia. Neurogastroenterology & Motility 32 (12). Fulltext not available.

Sellmer, Andreas, Pilsl, Bernadette, Beyer, Mandy, Pongratz, Herwig, Wirth, Lukas, Elz, Sigurd, Dove, Stefan, Henninger, Sven Julian, Spiekermann, Karsten, Polzer, Harald, Klaeger, Susan, Kuster, Bernhard, Böhmer, Frank D., Fiebig, Heinz-Herbert, Krämer, Oliver H. and Mahboobi, Siavosh (2020) A series of novel aryl-methanone derivatives as inhibitors of FMS-like tyrosine kinase 3 (FLT3) in FLT3-ITD-positive acute myeloid leukemia. European Journal of Medicinal Chemistry 193, p. 112232. Fulltext not available.

Fleischmann, Daniel, Maslanka-Figueroa, Sara, Beck, Sebastian, Abstiens, Kathrin, Witzgall, Ralph, Schweda, Frank, Tauber, Philipp and Goepferich, Achim

(2020) Adenovirus-Mimetic Nanoparticles: Sequential Ligand-Receptor Interplay as a Universal Tool for Enhanced In Vitro/In Vivo Cell Identification. ACS Applied Materials & Interfaces 12 (31), pp. 34689-34702. Fulltext not available.

Spinnler, Katrin, von Krüchten, Lara, Konieczny, Adam, Schindler, Lisa, Bernhardt, Günther and Keller, Max (2020) An Alkyne-functionalized Arginine for Solid-Phase Synthesis Enabling “Bioorthogonal” Peptide Conjugation. ACS Medicinal Chemistry Letters 11 (3), pp. 334-339. Fulltext not available.

Braun, Daniel

, Schlossmann, Jens and Haen, Ekkehard (2020) An innovative, time- and cost-saving method for the quantification of asymmetric dimethylarginine in serum by HPLC without evaporation. Separation Science Plus 3, pp. 571-577.

Braun, Daniel, Schlossmann, Jens

and Haen, Ekkehard (2020) An innovative, time‐ and cost‐saving method for the quantification of asymmetric dimethylarginine in serum by high‐performance liquid chromatography without evaporation. Separation Science Plus 3 (11-12), pp. 571-577.

Weber, Laura, Kuck, Katrin, Jürgenliemk, Guido, Heilmann, Jörg, Lipowicz, Bartosz and Vissiennon, Cica

(2020) Anti-Inflammatory and Barrier-Stabilising Effects of Myrrh, Coffee Charcoal and Chamomile Flower Extract in a Co-Culture Cell Model of the Intestinal Mucosa. Biomolecules 10 (7), p. 1033. Fulltext not available.

Buschmann, Jonas, Seiler, Theresa, Bernhardt, Günther, Keller, Max and Wifling, David (2020) Argininamide-type neuropeptide Y Y1 receptor antagonists: the nature of Nω-carbamoyl substituents determines Y1R binding mode and affinity. RSC Medicinal Chemistry 11 (2), pp. 274-282. Fulltext not available.

Ullah, Sami, Beer, Ronny, Fuhr, Uwe, Taubert, Max

, Zeitlinger, Markus, Kratzer, Alexander, Dorn, Christoph, Arshad, Usman, Kofler, Mario and Helbok, Raimund (2020) Brain Exposure to Piperacillin in Acute Hemorrhagic Stroke Patients Assessed by Cerebral Microdialysis and Population Pharmacokinetics. Neurocritical Care.

Liebchen, Uwe, Dorn, Christoph

, Kees, Martin, Schiesser, Selina, Hitzenbichler, Florian, Kees, Frieder and Paal, Michael (2020) Comment on “Meropenem, Cefepime, and Piperacillin Protein Binding in Patient Samples”. Therapeutic Drug Monitoring 42 (6), pp. 909-910. Fulltext not available.

Thalhauser, Stefanie, Peterhoff, David, Wagner, Ralf and Breunig, Miriam

(2020) Critical design criteria for engineering a nanoparticulate HIV-1 vaccine. Journal of Controlled Release 317, pp. 322-335. Fulltext not available.

Bohley, Marilena S., Birch, Emily, Baumann, Felix J., Dillinger, Andrea E., Tamm, Ernst R. and Goepferich, Achim M. (2020) Design of dye and superparamagnetic iron oxide nanoparticle loaded lipid nanocapsules with dual detectability in vitro and in vivo. International Journal of Pharmaceutics 585, p. 119433. Fulltext not available.

Schihada, Hannes

, Ma, Xiaoyuan, Zabel, Ulrike, Vischer, Henry F., Schulte, Gunnar

, Leurs, Rob, Pockes, Steffen

and Lohse, Martin J.

(2020) Development of a Conformational Histamine H3 Receptor Biosensor for the Synchronous Screening of Agonists and Inverse Agonists. ACS Sensors 5 (6), pp. 1734-1742. Fulltext not available.

Gruber, Corinna G., Pegoli, Andrea, Müller, Christoph, Grätz, Lukas, She, Xueke and Keller, Max (2020) Differently fluorescence-labelled dibenzodiazepinone-type muscarinic acetylcholine receptor ligands with high M2R affinity. RSC Medicinal Chemistry 11 (7), pp. 823-832. Fulltext not available.

Andreev, Stanislav, Pantsar, Tatu

, El-Gokha, Ahmed, Ansideri, Francesco, Kudolo, Mark, Anton, Débora Bublitz, Sita, Giulia

, Romasco, Jenny, Geibel, Christian, Lämmerhofer, Michael

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Yagati, Ajay Kumar

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(2019) Modifications at Arg and Ile Give Neurotensin(8−13) Derivatives with High Stability and Retained NTS1 Receptor Affinity. ACS Medicinal Chemistry Letters 10 (6), pp. 960-965. Fulltext not available.

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Schramm, Simon, Agnetta, Luca, Bermudez, Marcel, Gerwe, Hubert, Irmen, Matthias, Holze, Janine, Littmann, Timo, Wolber, Gerhard

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Dechant, Franz-Xaver, Dechant, Rebecca, Kandulski, Arne, Selgrad, Michael, Weber, Florian, Reischl, Udo, Wilczek, Wolf, Mueller, Martina and Weigand, Kilian

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Polykandriotis, Elias, Horch, Raymund E., Jost, Matthias, Arkudas, Andreas, Kees, Frieder and Schmitz, Marweh (2019) Can systemically administered antibiotics be detected in wound tissues and surfaces under negative pressure wound therapy? International Wound Journal 16 (2), pp. 503-510. Fulltext not available.

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Veselinović, Tanja, Scharpenberg, Martin, Heinze, Martin, Cordes, Joachim, Mühlbauer, Bernd, Juckel, Georg, Rüther, Eckart, Paulzen, Michael, Haen, Ekkehard, Hiemke, Christoph, Timm, Jürgen, Gründer, Gerhard, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference

, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference and make_name_string expected hash reference (2019) Dopamine D2 Receptor Occupancy Estimated From Plasma Concentrations of Four Different Antipsychotics and the Subjective Experience of Physical and Mental Well-Being in Schizophrenia. Journal of Clinical Psychopharmacology 39 (6), pp. 550-560. Fulltext not available.

Agnetta, Luca, Bermudez, Marcel

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Abstiens, Kathrin

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(2019) Gold-Tagged Polymeric Nanoparticles with Spatially Controlled Composition for Enhanced Detectability in Biological Environments. ACS Applied Nano Materials 2 (2), pp. 917-926. Fulltext not available.

Crespi, Stefano

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(2019) Heteroaryl azo dyes as molecular photoswitches. Nature Reviews Chemistry 3, pp. 133-146. Fulltext not available.

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(2019) Hydrogel microspheres evading alveolar macrophages for sustained pulmonary protein delivery. nternational Journal of Pharmaceutics 566, pp. 652-661. Fulltext not available.

Scharrenbroich, Jessica, Kaever, Volkhard, Dove, Stefan, Seifert, Roland and Schneider, Erich H. (2019) Hydrolysis of the non-canonical cyclic nucleotide cUMP by PDE9A: kinetics and binding mode. Naunyn-Schmiedeberg's Archives of Pharmacology 392 (2), pp. 199-208. Fulltext not available.

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(2019) Increasing the throughput of label-free cell assays to study the activation of G-protein-coupled receptors by using a serial agonist exposure protocol. Integrative Biology 11 (3), pp. 99-108. Fulltext not available.

Maslanka-Figueroa, Sara, Veser, Anika, Abstiens, Kathrin, Fleischmann, Daniel and Göpferich, Achim (2019) Influenza A virus mimetic nanoparticles trigger selective cell uptake. PNAS 116 (20), pp. 9831-9836. Fulltext not available.

Gergs, U.

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Bohley, Marilena, Haunberger, Alexandra and Göpferich, Achim

(2019) Intracellular availability of poorly soluble drugs from lipid nanocapsules. European Journal of Pharmaceutics and Biopharmaceutics 139, pp. 23-32. Fulltext not available.

Nussbaumer-Pröll, Alina Karoline, Eberl, Sabine, Reiter, Birgit, Stimpfl, Thomas, Dorn, Christoph

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Simon, P., Petroff, D., Dorn, Christoph

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(2019) N‑Arylation of NH-Sulfoximines via Dual Nickel Photocatalysis. Organic Letters 21, pp. 2740-2744.

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(2019) Photochromic peptidic NPY Y4-receptor ligands. Organic & Biomolecular Chemistry 17, pp. 2467-2478. Fulltext not available.

Heider, Fabian

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Nowak, Hartmuth, Weidemann, Caroline, Martini, Stefan, Oesterreicher, Zoe Anne, Dorn, Christoph, Adamzik, Michael, Kees, Frieder, Zeitlinger, Markus

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(2019) Repeated determination of moxifloxacin concentrations in interstitial space fluid of muscle and subcutis in septic patients. Journal of Antimicrobial Chemotherapy. Fulltext not available.

Schwindl, Sebastian, Kraus, Birgit and Heilmann, Jörg (2019) Secondary metabolites from the leaves of Juglans regia L. Biochemical Systematics and Ecology 83, pp. 130-136. Fulltext not available.

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(2019) Synthesis and biological evaluation of heteroalicyclic cyanoguanidines at histamine receptors. Archiv der Pharmazie 352 (9), p. 1900107. Fulltext not available.

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Makule, Edna E., Kraus, Birgit, Jürgenliemk, Guido, Heilmann, Jörg and Wiesneth, Stefan (2018) Dioic acid glycosides, tannins and methylated ellagic acid glycosides from Morella salicifolia bark. Phytochemistry Letters 28, pp. 76-83. Fulltext not available.

Gregoritza, Manuel (2018) Click Hydrogels for Controlled Local Antibody Delivery. PhD, Universität Regensburg.

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Böhr, Sebastian (2018) Therapeutisches Drug Monitoring der direkten oralen Antikoagulanzien. PhD, Universität Regensburg.

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Schramm, Andrea, Mueller-Thuemen, Philip, Littmann, Timo, Harloff, Manuela, Ozawa, Takeaki and Schlossmann, Jens

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Mayer, Larissa Joyce (2018) Effekte einer konsekutiven Aktivierung des MAP-Kinase-Signalwegs in humanen Melanozyten. PhD, Universität Regensburg.

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Makule, Edna (2018) Ethnopharmacological survey and phytochemical investigation of Maasai traditional medicinal plants from north-eastern Tanzania. PhD, Universität Regensburg.

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(2018) Micro RNA ‐622 is a novel mediator of tumorigenicity in melanoma by targeting Kirsten rat sarcoma. Pigment Cell & Melanoma Research 31 (5), pp. 614-629. Fulltext not available.

Littmann, Timo, Ozawa, Takeaki, Hoffmann, Carsten, Buschauer, Armin

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(2018) A split luciferase-based probe for quantitative proximal determination of Gαq signalling in live cells. Scientific Reports 8 (1), p. 17179.

Walz, J. M., Bemme, S., Reichl, S., Akman, S., Breuß, H., Süsskind, D., Glitz, B., Müller, V. C., Wagenfeld, L., Gabel-Pfisterer, A., Aisenbrey, S., Engelmann, K., Koutsonas, A., Krohne, T. U. and Stahl, A.

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Schmidberger, Andreas, Schupfner, Robert and Matysik, Frank-Michael

(2018) Development of an analytical strategy for the determination of 228Th and 232Th in ivory based on the combined use of ICP-MS and α-spectrometry. Journal of Radioanalytical and Nuclear Chemistry 318 (3), pp. 2007-2011. Fulltext not available.

Koehler, Julia, Brandl, Ferdinand and Goepferich, Achim

(2018) Hydrogel wound dressing for bioactive treatment of acute and chronic wounds. European Polymer Journal 100, pp. 1-11. Fulltext not available.

Dorn, Christoph, Kratzer, Alexander, Liebchen, Uwe, Schleibinger, Michael, Murschhauser, Alexandra, Schlossmann, Jens

, Kees, Frieder, Simon, Philipp and Kees, Martin G. (2018) Impact of Experimental Variables on the Protein Binding of Tigecycline in Human Plasma as Determined by Ultrafiltration. Journal of Pharmaceutical Sciences 107 (2), pp. 739-744. Fulltext not available.

Dillinger, Andrea E., Guter, Michaela, Froemel, Franziska, Weber, Gregor R., Perkumas, Kristin, Stamer, W. Daniel, Ohlmann, Andreas, Fuchshofer, Rudolf and Breunig, Miriam

(2018) Intracameral Delivery of Layer‐by‐Layer Coated siRNA Nanoparticles for Glaucoma Therapy. Small 14 (50), p. 1803239. Fulltext not available.

Wiesneth, Stefan, Aas, Gregor, Heilmann, Jörg and Jürgenliemk, Guido (2018) Investigation of the flavan-3-ol patterns in willow species during one growing-season. Phytochemistry 145, pp. 26-39. Fulltext not available.

Thamm, M.

, Sturm, K., Schlossmann, J.

and Scheiner, R. (2018) Levels and activity of cyclic guanosine monophosphate-dependent protein kinase in nurse and forager honeybees. Insect Molecular Biology 27 (6), pp. 815-823. Fulltext not available.

Sellmer, Andreas, Stangl, Hubert, Beyer, Mandy, Grünstein, Elisabeth, Leonhardt, Michel, Pongratz, Herwig, Eichhorn, Emerich, Elz, Sigurd, Striegl, Birgit, Jenei-Lanzl, Zsuzsa, Dove, Stefan, Straub, Rainer H., Krämer, Oliver H. and Mahboobi, Siavosh (2018) Marbostat-100 Defines a New Class of Potent and Selective Antiinflammatory and Antirheumatic Histone Deacetylase 6 Inhibitors. Journal of Medicinal Chemistry 61 (8), pp. 3454-3477. Fulltext not available.

Chuskit, Deachen, Chaudhary, Renu, Venugopalan, Paloth, König, Burkhard

and Natarajan, Palani (2018) Oxidative homodimerization of substituted olefins by DDQ visible light photocatalysis. Organic Chemistry Frontiers 5, pp. 3553-3556. Fulltext not available.

Schoretsanitis, Georgios, de Leon, Jose, Haen, Ekkehard, Stegmann, Benedikt, Hiemke, Christoph, Gründer, Gerhard and Paulzen, Michael (2018) Pharmacokinetics of risperidone in different application forms – Comparing long-acting injectable and oral formulations. European Neuropsychopharmacology 28 (1), pp. 130-137. Fulltext not available.

Mathioudaki, Angeliki, Berzesta, Ariola, Kypriotakis, Zacharias, Skaltsa, Helen and Heilmann, Jörg (2018) Phenolic metabolites from Hypericum kelleri Bald., an endemic species of Crete (Greece). Phytochemistry 146, pp. 1-7. Fulltext not available.

Paolillo, Michael

, Peters, Stefanie, Schramm, Andrea, Schlossmann, Jens

and Feil, Robert

(2018) Real-Time Imaging Reveals Augmentation of Glutamate-Induced Ca2+ Transients by the NO-cGMP Pathway in Cerebellar Granule Neurons. International Journal of Molecular Sciences 19, p. 2185.

Jackson, Scott M., Manolaridis, Ioannis, Kowal, Julia

, Zechner, Melanie, Taylor, Nicholas M. I.

, Bause, Manuel, Bauer, Stefanie, Bartholomaeus, Ruben, Bernhardt, Günther, König, Burkhard

, Buschauer, Armin, Stahlberg, Henning

, Altmann, Karl-Heinz and Locher, Kaspar P. (2018) Structural basis of small-molecule inhibition of human multidrug transporter ABCG2. Nature Structural & Molecular Biology 25 (4), pp. 333-340. Fulltext not available.

Dolles, Dominik, Hoffmann, Matthias, Gunesch, Sandra, Marinelli, Oliviero, Möller, Jan

, Santoni, Giorgio, Chatonnet, Arnaud, Lohse, Martin J.

, Wittmann, Hans-Joachim, Strasser, Andrea, Nabissi, Massimo, Maurice, Tangui and Decker, Michael

(2018) Structure–Activity Relationships and Computational Investigations into the Development of Potent and Balanced Dual-Acting Butyrylcholinesterase Inhibitors and Human Cannabinoid Receptor 2 Ligands with Pro-Cognitive in Vivo Profiles. Journal of Medicinal Chemistry 61 (4), pp. 1646-1663. Fulltext not available.

Plokhikh, I. V.

, Charkin, D. O., Verchenko, V. Yu., Kuznetsov, A. N., Tsirlin, A. A., Kazakov, S. M.

and Shevelkov, A. V. (2018) Synthesis, crystal structure and physical properties of europium – manganese fluoride pnictides, EuMnPnF (Pn = P, As, Sb). Journal of Solid State Chemistry 258, pp. 682-690. Fulltext not available.

Peña-Solórzano, Diana, Scholler, Matthias, Bernhardt, Günther, Buschauer, Armin

, König, Burkhard

and Ochoa-Puentes, Cristian (2018) Tariquidar-Related Chalcones and Ketones as ABCG2 Modulators. ACS Medicinal Chemistry Letters 9, pp. 854-859. Fulltext not available.

Uchida, Hitoshi, Matsumura, Shinji, Katano, Tayo, Watanabe, Masahiko

, Schlossmann, Jens

and Ito, Seiji (2018) Two isoforms of cyclic GMP-dependent kinase-I exhibit distinct expression patterns in the adult mouse dorsal root ganglion. Molecular Pain 14, p. 174480691879640. Fulltext not available.

Brosig, Andreas Michael (2017) Technical comparison of four different extracorporeal photopheresis systems. PhD, Universität Regensburg.

Chen, Kang, Berg, Nele, Gschwind, Ruth Maria

and König, Burkhard

(2017) Selective Single C(sp3)−F Bond Cleavage in Trifluoromethylarenes: Merging Visible-Light Catalysis with Lewis Acid Activation. Journal of the American Chemical Society 139, pp. 18444-18447. Fulltext not available.

She, Xueke, Pegoli, Andrea, Mayr, Judith, Hübner, Harald, Bernhardt, Günther

, Gmeiner, Peter and Keller, Max

(2017) Heterodimerization of Dibenzodiazepinone-Type Muscarinic Acetylcholine Receptor Ligands Leads to Increased M2R Affinity and Selectivity. ACS Omega 2 (10), pp. 6741-6754.

Kuhn, Kilian (2017) Molecular Tools for the NPY Y₄ Receptor Derived from the C-Terminus of hPP and from Argininamide-type Y₁R Antagonists. PhD, Universität Regensburg.

Oswald, Mira (2017) Targeted CNS Delivery via Nanoparticulate Drug Delivery Systems. PhD, Universität Regensburg.

Wetzl, Veronika (2017) Fibrose-assoziierte Biomarker – Einfluss der Behandlung mit Serelaxin im murinen Nierenfibrose-Modell und prädiktiver Aussagewert in der pulmonalen Hypertonie. PhD, Universität Regensburg.

Scheck, Luisa (2017) Characterization of TSPO 18 kDa in neurosteroid synthesis and mitochondrial metabolism. PhD, Universität Regensburg.

Endres, Wolfgang (2017) Reparier Dich Selbst! Working Paper. (Submitted) Fulltext restricted.

Hammer, Nadine (2017) Hydrogels for the Controlled Release of Protein Pharmaceuticals. PhD, Universität Regensburg.

Strasser, Andrea, Wittmann, Hans-Joachim and Seifert, Roland (2017) Binding kinetics and pathways of ligands to GPCRs. Trends in Pharmacological Sciences. (In Press) Fulltext not available.

Dessauer, Carmen W., Watts, Val J., Ostrom, Rennolds S., Conti, Marco, Dove, Stefan and Seifert, Roland (2017) International Union of Basic and Clinical Pharmacology. CI. Structures and Small Molecule Modulators of Mammalian Adenylyl Cyclases. Pharmacological Reviews 69 (2), pp. 93-139. Fulltext not available.

Wiesneth, Stefan, Aas, Gregor, Heilmann, Jörg and Jürgenliemk, Guido (2017) Comparative investigation of the flavan-3-ol patterns in two willows during one growing season. In: International PhD students/Postdocs meeting of the German Pharmaceutical Society (DPhG), 29.-31. März 2017, Frankfurt am Main, Germany. Fulltext not available.

Schlossmann, Jens, Schinner, Elisabeth, Wetzl, Veronika, Schramm, Andrea, Kees, Frieder, Sandner, Peter, Stasch, Johannes-Peter and Hofmann, Franz (2017) Inhibition of the TGFβ signalling pathway by cGMP and cGMP‐dependent kinase I in renal fibrosis. FEBS openbio 7 (4), pp. 550-561.

Wittmann, Hans-Joachim and Strasser, Andrea (2017) Competitive association binding kinetic assays: a new tool to detect two different binding orientations of a ligand to its target protein under distinct conditions? Naunyn-Schmiedeberg's Archives of Pharmacology. (In Press) Fulltext not available.

Dorn, Christoph

, Nowak, Hartmuth, Weidemann, Caroline, Martini, Stefan, Zeitlinger, Markus, Adamzik, Michael and Kees, Frieder K. (2017) Decreased protein binding of moxifloxacin in patients with sepsis? GMS Infectious Diseases 2017 (5), Doc03.

Koehler, Julia, Verheyen, Leonie, Hedtrich, Sarah, Brandl, Ferdinand P. and Goepferich, Achim M. (2017) Alkaline poly(ethylene glycol)-based hydrogels for a potential use as bioactive wound dressings. Journal of Biomedical Materials Research Part A 105 (12), pp. 3360-3368. Fulltext not available.

Schäfer, Claudia, Göder, Anja, Beyer, Mandy, Kiweler, Nicole, Mahendrarajah, Nisintha, Rauch, Anke, Nikolova, Teodora, Stojanovic, Natasa, Wieczorek, Martin, Reich, Thomas R., Tomicic, Maja T., Linnebacher, Michael, Sonnemann, Jürgen, Dietrich, Sascha, Sellmer, Andreas, Mahboobi, Siavosh, Heinzel, Thorsten, Schneider, Günter and Krämer, Oliver H. (2017) Class I histone deacetylases regulate p53/NF-κB crosstalk in cancer cells. Cellular Signalling 29, pp. 218-225. Fulltext not available.

Gregoritza, Manuel

, Messmann, Viktoria, Abstiens, Kathrin, Brandl, Ferdinand and Göpferich, Achim

(2017) Controlled Antibody Release from Degradable Thermoresponsive
Hydrogels Cross-Linked by Diels−Alder Chemistry. Biomacromolecules 18, pp. 2410-2418. Fulltext not available.

Makule, Edna, Schmidt, Thomas J.

, Heilmann, Jörg and Kraus, Birgit (2017) Diarylheptanoid Glycosides of Morella salicifolia Bark. Molecules 22, p. 2266.

Stojanovic, N., Hassan, Z., Wirth, M., Wenzel, P., Beyer, M., Schäfer, C., Brand, P., Kroemer, A., Stauber, R. H., Schmid, R. M., Arlt, A., Sellmer, A., Mahboobi, S., Rad, R., Reichert, M., Saur, D., Krämer, O. H. and Schneider, G. (2017) HDAC1 and HDAC2 integrate the expression of p53 mutants in pancreatic cancer. Oncogene 36 (13), pp. 1804-1815. Fulltext not available.

Mahendrarajah, Nisintha, Borisova, Marina E., Reichardt, Sigrid, Godmann, Maren, Sellmer, Andreas, Mahboobi, Siavosh, Haitel, Andrea, Schmid, Katharina, Kenner, Lukas

, Heinzel, Thorsten, Beli, Petra and Krämer, Oliver H. (2017) HSP90 is necessary for the ACK1-dependent phosphorylation of STAT1 and STAT3. Cellular Signalling 39, pp. 9-17. Fulltext not available.

Guter, Michaela and Breunig, Miriam (2017) Hyaluronan as a promising excipient for ocular drug delivery. European Journal of Pharmaceutics and Biopharmaceutics 113, pp. 34-49. Fulltext not available.

Kuhn, Kilian K., Littmann, Timo, Dukorn, Stefanie, Tanaka, Miho, Keller, Max, Ozawa, Takeaki, Bernhardt, Günther and Buschauer, Armin

(2017) In Search of NPY Y4R Antagonists: Incorporation of Carbamoylated Arginine, Aza-Amino Acids, or d-Amino Acids into Oligopeptides Derived from the C-Termini of the Endogenous Agonists. ACS Omega 2 (7), pp. 3616-3631.

Ittner, Karl, Koppenberg, Joachim and Walter, Ute (2017) Indikationsfremde Anwendung von Medikamenten und Medizinprodukten in der Notfallmedizin. Der Notarzt 33 (04), pp. 178-188. Fulltext not available.

Slattery, David A., Neumann, Inga D., Flor, Peter J. and Zoicas, Iulia (2017) Pharmacological modulation of metabotropic glutamate receptor subtype 5 and 7 impairs extinction of social fear in a time-point-dependent manner. Behavioural Brain Research 328, pp. 57-61. Fulltext not available.

Wutz, Daniel-Fabian, Gluhacevic, Dino, Chakrabarti, A., Schmidtkunz, K., Robaa, D., Erdmann, F., Romier, C., Sippl, W., Jung, M. and König, Burkhard

(2017) Photochromic histone deacetylase inhibitors based on
dithienylethenes and fulgimides. Organic & Biomolecular Chemistry 15, pp. 4882-4896. Fulltext not available.

Backofen, Michael, Schwach, Gregoire, Koechling, Wolfgang, Weiss, Torsten and Goepferich, Achim

(2017) Polyanion based controlled release system for the GnRH-receptor antagonist degarelix. European Journal of Pharmaceutical Sciences 104, pp. 65-71. Fulltext not available.

Tomasetti, Luise and Breunig, Miriam (2017) Preventing Obstructions of Nanosized Drug Delivery
Systems by the Extracellular Matrix. Advanced Healthcare Materials, pp. 1-16. Fulltext not available.

Pegoli, Andrea

, She, Xueke, Wifling, David

, Hübner, Harald, Bernhardt, Günther, Gmeiner, Peter

and Keller, Max (2017) Radiolabeled Dibenzodiazepinone-Type Antagonists Give Evidence of Dualsteric Binding at the M2 Muscarinic Acetylcholine Receptor. Journal of Medicinal Chemistry 60 (8), pp. 3314-3334. Fulltext not available.

Meyer, Andreas Uwe

, Wimmer, Alexander and König, Burkhard

(2017) Visible-Light-Accelerated C−H Sulfinylation of Heteroarenes. Angewandte Chemie International Edition 56, pp. 409-412. Fulltext not available.

Onuoha, Mary Remigius Agatha (2016) Therapeutic Drug Monitoring of Antipsychotics - HPLC Analytical Method Development and Pharmaceutical Advices to the Ward Clinicians - For Successful Individualized Therapy. PhD, Universität Regensburg.

Strasser, Andrea and Wittmann, Hans-Joachim (2016) Molecular Modelling Approaches for the Analysis of Histamine Receptors and Their Interaction with Ligands. In: Handbook of Experimental Pharmacology. (In Press) Fulltext not available.

Lieb, Sebastian (2016) Investigations on histamine and neuropeptide Y receptors by label-free and label-dependent methods. PhD, Universität Regensburg.

Lieb, Sebastian, Littmann, Timo, Plank, Nicole, Felixberger, Johannes, Tanaka, Miho, Schäfer, Thorsten, Krief, Stéphane, Elz, Sigurd, Friedland, Kristina, Bernhardt, Günther, Wegener, Joachim, Ozawa, Takeaki and Buschauer, Armin (2016) Label-free versus conventional cellular assays: functional investigations on the human histamine H1 receptor. Pharmacological Research 114, pp. 13-26. Fulltext not available.

Wiesneth, Stefan, Heilmann, Jörg and Jürgenliemk, Guido (2016) Total phenolic and tannins determination: A modification of Ph. Eur. 2.8.14 suitable for high-throughput screenings. In: Annual Meeting of the German Pharmaceutical Society (DPhG), 4.-7. Okt. 2016, München, Germany. Fulltext not available.

Sadek, Bassem, Khan, Nadia, Darras, Fouad H., Pockes, Steffen

and Decker, Michael (2016) The dual-acting AChE inhibitor and H3 receptor antagonist UW-MD-72 reverses amnesia induced by scopolamine or dizocilpine in passive avoidance paradigm in rats. Physiology & Behavior 165, pp. 383-391. Fulltext not available.

Töpper, Christoph, Steinbach, Cathérine Louise, Dorn, Christoph

, Kratzer, Alexander, Wicha, Sebastian G., Schleibinger, Michael, Liebchen, Uwe, Kees, Frieder, Salzberger, Bernd and Kees, Martin G. (2016) Variable linezolid exposure in ICU patients—possible role of drug-drug interactions. Therapeutic Drug Monitoring 38 (5), pp. 573-578. Fulltext not available.

Naporra, Franziska, Gobleder, Susanne, Wittmann, Hans-Joachim, Spindler, Julia, Bodensteiner, Michael, Bernhardt, Günther, Hübner, Harald, Gmeiner, Peter, Elz, Sigurd and Strasser, Andrea (2016) Dibenzo[b,f][1,4]oxazepines and dibenzo[b,e]oxepines: Influence of the chlorine substitution pattern on the pharmacology at the H1R, H4R, 5-HT2AR and other selected GPCRs. Pharmacological Research 113, pp. 610-625. (In Press) Fulltext not available.

Kunath, Julia (2016) Designermoleküle hemmen die Semaphorin 3F Wirkung in vitro, haben aber keinen Einfluss auf den Verlauf der experimentellen Arthritis. PhD, Universität Regensburg.

Untergehrer, Monika (2016) Analytische Untersuchungen zu phenolischen Inhaltsstoffen aus Salicis Cortex unter besonderer Berücksichtigung ihrer Metabolisierung. PhD, Universität Regensburg.

Schlossmann, Jens, Wetzl, Veronika, Schinner, Elisabeth, Kees, Frieder K., Hofmann, Franz and Faerber, Lothar

(2016) Involvement of cyclic guanosine monophosphate-dependent protein kinase I in renal antifibrotic effects of serelaxin. Frontiers in Pharmacology 7 (195), pp. 1-27.

Hennig, Robert (2016) Multivalent nanoparticles for the treatment of ocular diseases. PhD, Universität Regensburg.

Wurster, Eva-Christina (2016) Layer-by-Layer assembled thin films for drug delivery: Interactions at the nano-bio interface. PhD, Universität Regensburg.

Korber, Nikolaus and Friedrich, Ute (2016) A Step in Between: [Sn3Bi3]5− and Its Structural Relationship to [Sn3Bi5]3− and [Sn4Bi4]4−. Chemistry Open 5 (4), pp. 306-310.

Kuhn, Kilian K., Ertl, Thomas, Dukorn, Stefanie, Keller, Max, Bernhardt, Günther, Reiser, Oliver

and Buschauer, Armin (2016) High affinity agonists of the neuropeptide Y (NPY) Y4 receptor derived from the C-terminal pentapeptide of human pancreatic polypeptide (hPP): synthesis, stereochemical discrimination and radiolabeling. Journal of Medicinal Chemistry 59 (13), pp. 6045-6058. Fulltext not available.

Gobleder, Susanne (2016) Synthesis and pharmacological characterization of new histamine H1-/H4-receptor ligands derived from the atypical antipsychotic drug Clozapine. PhD, Universität Regensburg.

Wiesneth, Stefan (2016) Polyphenole aus Salix – Neue Teile im phytochemischen Puzzle (Polyphenols from Salix – new insights into the phytochemical composition). In: 3. Doktorandenkolleg der WALA Heilmittel GmbH (PhD students meeting), 30. April 2016, Bad Boll / Eckwälden, Germany. Fulltext not available.

Kratzer, Alexander Ludwig (2016) Entwicklung und Erprobung von HPLC-basierten Methoden für das Therapeutische Drug-Monitoring von Betalaktam-Antibiotika, Linezolid und Tigecyclin – Bestimmung von freien und totalen Konzentrationen im Plasma von Intensivpatienten. PhD, Universität Regensburg.

Geyer, Roland, Nordemann, Uwe, Strasser, Andrea, Wittmann, Hans-Joachim and Buschauer, Armin (2016) Conformational restriction and enantioseparation increase potency and selectivity of cyanoguanidine-type histamine H4 receptor agonists. Journal of Medicinal Chemistry 59 (7), pp. 3452-3470. Fulltext not available.

Huber, Stefan (2016) Investigations on bendamustine esters as new antitumor agents and the role of ABCG2 as a surrogate marker of breast cancer initiating cells. PhD, Universität Regensburg.

Limmer, Franziska (2016) Funktionelle Analyse der cGMP-abhängigen Proteinkinase I in der Niere, insbesondere im dicken aufsteigenden Ast der Henle-Schleife. PhD, Universität Regensburg.

Edalat, Lena, Stegen, Benjamin, Klumpp, Lukas, Haehl, Erik, Schilbach, Karin, Lukowski, Robert, Kühnle, Matthias, Bernhardt, Günther, Buschauer, Armin, Zips, Daniel, Ruth, Peter and Huber, Stephan M. (2016) BK K+ channel blockade inhibits radiation-induced migration/brain infiltration of glioblastoma cells. Oncotarget 7 (12), pp. 14259-14278. Fulltext not available.

Felixberger, Johannes (2016) Luciferase complementation for the determination of arrestin recruitment: Investigations at histamine and NPY receptors. PhD, Universität Regensburg.

Stangl, Hubert Werner (2016) Arthritis and cholinergic transition of sympathetic nerve fibers. PhD, Universität Regensburg.

Vögeler, Jessica (2016) Pharmakotherapie und Humanpharmakologische Untersuchungen bei Patienten mit DME (Diabetisches Makulaödem) und PDR (Proliferative Diabetische Retinopathie) anhand klinischer Parameter und inflammatorischer Biomarker. PhD, Universität Regensburg.

Lorenz, Peter, Knittel, Diana N., Conrad, Jürgen, Lotter, Eva M., Heilmann, Jörg, Stintzing, Florian C. and Kammerer, Dietmar R. (2016) 1-Acetyl-3-[(3R)-hydroxyfatty acyl]glycerols: Lipid Compounds fromEuphrasia rostkovianaHayneandE. tetraquetra(Bréb.)Arrond. Chemistry & Biodiversity 13 (5), pp. 602-612. Fulltext not available.

Hammer, Sebastian, Gobleder, Susanne, Naporra, Franziska, Wittmann, Hans-Joachim, Elz, Sigurd, Heinrich, Markus

and Strasser, Andrea (2016) 2,4-Diaminopyrimidines as dual ligands at the histamine H1 and H4 receptor - H1/H4-receptor selectivity. Bioorganic & Medicinal Chemistry Letters 26, pp. 292-300. Fulltext not available.

Dolles, Dominik, Nimczick, Martin, Scheiner, Matthias, Ramler, Jacqueline, Stadtmüller, Patricia, Sawatzky, Edgar, Drakopoulos, Antonios, Sotriffer, Christoph, Wittmann, Hans-Joachim, Strasser, Andrea and Decker, Michael (2016) Aminobenzimidazoles and structural isomers as templates for dual-acting butyrylcholinesterase inhibitors and hCB2R ligands to combat neurodegenerative disorders. ChemMedChem 11 (12), pp. 1270-1283. Fulltext not available.

Bucher, Felicitas

, Walz, Johanna M., Bühler, Anima, Aguilar, Edith, Lange, Clemens, Diaz-Aguilar, Sophia, Martin, Gottfried, Schlunck, Günther, Agostini, Hansjürgen, Friedlander, Martin and Stahl, Andreas (2016) CNTF Attenuates Vasoproliferative Changes Through Upregulation of SOCS3 in a Mouse-Model of Oxygen-Induced Retinopathy. Investigative Opthalmology & Visual Science 57 (10), p. 4017. Fulltext not available.

Hennig, Robert, Kuespert, Sabrina, Haunberger, Alexandra, Goepferich, Achim

and Fuchshofer, Rudolf (2016) Cyclic RGD peptides target human trabecular meshwork cells while ameliorating connective tissue growth factor-induced fibrosis. Journal of Drug Targeting 24 (10), pp. 952-959. Fulltext not available.

Gregoritza, Manuel, Messmann, Viktoria, Goepferich, Achim and Brandl, Ferdinand (2016) Design of hydrogels for delayed antibody release utilizing hydrophobic association and Diels-Alder chemistry in tandem. Journal of Materials Chemistry B 4 (19), pp. 3398-3408. Fulltext not available.

Gregoritza, Manuel, Messmann, Viktoria, Goepferich, Achim M.

and Brandl, Ferdinand P. (2016) Design of hydrogels for delayed antibody release utilizing hydrophobic association and Diels–Alder chemistry in tandem. Journal of Materials Chemistry B 4 (19), pp. 3398-3408. Fulltext not available.

Sawatzky, Edgar, Wehle, Sarah, Kling, Beata, Wendrich, Jan, Bringmann, Gerhard, Sotriffer, Christoph A., Heilmann, Jörg and Decker, Michael (2016) Discovery of Highly Selective and Nanomolar Carbamate-Based Butyrylcholinesterase Inhibitors by Rational Investigation into Their Inhibition Mode. Journal of Medicinal Chemistry 59 (5), pp. 2067-2082. Fulltext not available.

Obreque-Balboa, José-Esteban, Sun, Qiu, Bernhardt, Günther, König, Burkhard

and Buschauer, Armin (2016) Flavonoid derivatives as selective ABCC1 modulators: Synthesis and functional characterization. European Journal of Medicinal Chemistry 109, pp. 124-133. Fulltext not available.

Hering, Thea, Mühldorf, Bernd, Wolf, Robert

and König, Burkhard

(2016) Halogenase-Inspired Oxidative Chlorination Using Flavin
Photocatalysis. Angewandte Chemie International Edition 55, pp. 5342-5345. Fulltext not available.

Kariminia, Amina, Holtan, Shernan G., Ivison, Sabine, Rozmus, Jacob, Hebert, Marie-Josée, Martin, Paul J., Lee, Stephanie J., Wolff, Daniel, Subrt, Peter, Abdossamadi, Sayeh, Sung, Susanna, Storek, Jan, Levings, Megan, Aljurf, Mahmoud, Arora, Mukta, Cutler, Corey, Gallagher, Geneviève, Kuruvilla, John, Lipton, Jeff, Nevill, Thomas J., Newell, Laura F., Panzarella, Tony, Pidala, Joseph, Popradi, Gizelle, Szwajcer, David, Tay, Jason

, Toze, Cynthia L., Walker, Irwin, Couban, Stephen, Storer, Barry E. and Schultz, Kirk R.

(2016) Heterogeneity of chronic graft-versus-host disease biomarkers: association with CXCL10 and CXCR3+ NK cells. Blood 127 (24), pp. 3082-3091. Fulltext not available.

Dove, Stefan (2016) Mammalian Nucleotidyl Cyclases and Their Nucleotide Binding Sites. In: Seifert, Roland, (ed.) Non-canonical Cyclic Nucleotides. Handbook of Experimental Pharmacology, 238. Springer International Publishing, Cham, Switzerland, pp. 49-66. ISBN 978-3-319-52673-7 (online), 978-3-319-52671-3 (print). Fulltext not available.

Keller, Max, Kuhn, Kilian K., Einsiedel, Jürgen, Hübner, Harald, Biselli, Sabrina, Mollereau, Catherine

, Wifling, David, Svobodova, Jaroslava, Bernhardt, Günther, Cabrele, Chiara

, Vanderheyden, Patrick, Gmeiner, Peter

and Buschauer, Armin (2016) Mimicking of arginine by functionalized Nω-carbamoylated arginine as a new broadly applicable approach to labeled bioactive peptides: high affinity angiotensin, neuropeptide Y, neuropeptide FF and neurotensin receptor ligands as examples. Journal of Medicinal Chemistry 59 (5), pp. 1925-1945. Fulltext not available.

Gregoritza, Manuel, Goepferich, Achim

and Brandl, Ferdinand (2016) Polyanions effectively prevent protein conjugation and activity loss during hydrogel cross-linking. Journal of Controlled Release 238, pp. 92-102. Fulltext not available.

Khan, Nadia, Saad, Ali, Nurulain, Syed M., Darras, Fouad H., Decker, Michael and Sadek, Bassem (2016) The dual-acting H3 receptor antagonist and AChE inhibitor UW-MD-71 dose-dependently enhances memory retrieval and reverses dizocilpine-induced memory impairment in rats. Behavioural Brain Research 297, pp. 155-164. Fulltext not available.

Kratzer, Alexander, Kees, Frieder and Dorn, Christoph

(2016) Unbound fraction of fluconazole and linezolid in human plasma as determined by ultrafiltration: Impact of membrane type. Journal of Chromatography B 1039, pp. 74-78. Fulltext not available.

Huang, Guozheng

, Schramm, Simon, Heilmann, Jörg, Biedermann, David, Křen, Vladimír and Decker, Michael (2016) Unconventional application of the Mitsunobu reaction: Selective flavonolignan dehydration yielding hydnocarpins. Beilstein Journal of Organic Chemistry 12, pp. 662-669. Fulltext not available.

Koehler, Julia, Wallmeyer, Leonie, Hedtrich, Sarah, Goepferich, Achim M.

and Brandl, Ferdinand P. (2016) pH-Modulating Poly(ethylene glycol)/Alginate Hydrogel Dressings for the Treatment of Chronic Wounds. Macromolecular Bioscience 17 (5), p. 1600369. Fulltext not available.

Kirchhof, Susanne (2015) Diels Alder Hydrogels as Intraocular Drug Delivery Systems for Antibodies. PhD, Universität Regensburg.

Wiesneth, Stefan, Petereit, Frank and Jürgenliemk, Guido (2015) Salix daphnoides: A Screening for oligomeric and polymeric flavan-3-ols. In: 7th International Conference on Polyphenols and Health (ICPH), 27.-30. Okt. 2015, Tours, France. Fulltext not available.

Meinel, Thomas Raphael (2015) Neuronale alpha-adrenerge Stimulation von IFN-gamma, IL-6 und CXCL1 in murinen Milzen im Tiermodell der Arthritisspätphase. PhD, Universität Regensburg.

Nguyen, Tri Hieu (2015) Phytochemical and biological investigation of the bark of Garcinia fusca Pierre. PhD, Universität Regensburg.

Helm, Klaus (2015) Synthese und funktionelle In-vitro-Pharmakologie neuer Liganden des 5-HT2A-Rezeptors aus der Klasse der Tryptamine. PhD, Universität Regensburg.

Werner, Kristin, Kälble, Solveig, Wolter, Sabine, Schneider, Erich H., Buschauer, Armin, Neumann, Detlef and Seifert, Roland (2015) Flow cytometric analysis with a fluorescent formyl peptide receptor ligand as a new method to study the pharmacological profile of the histamine H2-receptor. Naunyn Schmiedebergs Archives of Pharmacology 388 (10), pp. 1039-1052. Fulltext not available.

Wolferstetter, Stefanie, Reinders, Jörg, Schwede, Frank, Ruth, Peter, Schinner, Elisabeth and Schlossmann, Jens (2015) Interaction of cCMP with the cGK, cAK and MAPK Kinases in Murine Tissues. PLoS ONE 10 (5), e0126057.

Keller, Max, Schindler, Lisa, Bernhardt, Günther and Buschauer, Armin (2015) Towards labeled argininamide-type NPY Y1 receptor antagonists: Identification of a favorable propionylation site in BIBO3304. Archiv der Pharmazie 348 (6), pp. 390-398. Fulltext not available.

Rothenhöfer, Martin, Grundmann, Marco, Bernhardt, Günther, Matysik, Frank-Michael and Buschauer, Armin (2015) High performance anion exchange chromatography with pulsed amperometric detection (HPAEC–PAD) for the sensitive determination of hyaluronan oligosaccharides. Journal of Chromatography B 988 (C), pp. 106-115. Fulltext not available.

Wifling, David (2015) Constitutive activity of the human histamine H4 receptor: Molecular modelling, binding and functional studies on wild-type and mutant H4R orthologs. PhD, Universität Regensburg.

Wiesneth, Stefan, Petereit, Frank and Jürgenliemk, Guido (2015) Polymere Proanthocyanidine aus der Rinde von Salix daphnoides (Polymeric proanthocyanidins from the bark of Salix daphnoides). In: 4. Young Researcher Meeting, 13.-14. März 2015, Münster, Germany. Fulltext not available.

Mahli, Abdo (2015) Novel in vitro model for combined effects of alcohol and free fatty acids on hepatocellular lipid accumulation and inflammation. PhD, Universität Regensburg.

Wifling, David, Bernhardt, Günther, Dove, Stefan and Buschauer, Armin (2015) The extracellular loop 2 (ECL2) of the human histamine H4 receptor substantially contributes to ligand binding and constitutive activity. PLoS One 10 (1), pp. 1-14.

Baumeister, Paul, Erdmann, Daniela, Biselli, Sabrina, Kagermeier, Nicole, Elz, Sigurd, Bernhardt, Günther and Buschauer, Armin (2015) 3HUR-DE257: Development of a tritium-labeled squaramide-type selective histamine H2 receptor antagonist. ChemMedChem 10 (1), pp. 83-93. Fulltext not available.

Dolles, Dominik, Nimczick, Martin, Scheiner, Matthias, Ramler, Jacqueline, Stadtmüller, Patricia, Sawatzky, Edgar, Drakopoulos, Antonios

, Sotriffer, Christoph, Wittmann, Hans-Joachim, Strasser, Andrea and Decker, Michael (2015) Aminobenzimidazoles and Structural Isomers as Templates for Dual-Acting Butyrylcholinesterase Inhibitors andhCB2R Ligands To Combat Neurodegenerative Disorders. ChemMedChem 11 (12), pp. 1270-1283. Fulltext not available.

Orlando, Zoya, Lengers, Isabelle, Melzig, Matthias F., Buschauer, Armin, Hensel, Andreas and Jose, Joachim (2015) Autodisplay of human hyaluronidase Hyal-1 on Escherichia coli and identification of plant-derived enzyme inhibitors. Molecules 20 (9), pp. 15449-15468.

Wittmann, Hans-Joachim and Strasser, Andrea (2015) Binding pathway of histamine to the hH4R, observed by unconstrained molecular dynamics. Bioorganic & Medicinal Chemistry Letters 25, pp. 1259-1268. Fulltext not available.

Schinner, Elisabeth, Wetzl, Veronika and Schlossmann, Jens (2015) Cyclic Nucleotide Signalling in Kidney Fibrosis. International Journal of Molecular Sciences 16, pp. 2320-2351.

Kirchhof, Susanne, Gregoritza, Manuel, Messmann, Viktoria, Hammer, Nadine, Göpferich, Achim and Brandl, Ferdinand (2015) Diels-Alder hydrogels with enhanced stability: First step toward controlled release of bevacizumab. European Journal of Pharmaceutics and Biopharmaceutics 96, pp. 217-225. Fulltext not available.

Kirchhof, Susanne, Abrami, Michela, Messmann, Viktoria, Hammer, Nadine, Goepferich, Achim, Grassi, Mario and Brandl, Ferdinand (2015) Diels–Alder hydrogels for controlled antibody release: Correlation between mesh size and release rate. Molecular Pharmaceutics 12 (9), pp. 3358-3368. Fulltext not available.

Lübker, Carolin, Dove, Stefan, Tang, Wei-Jen, Bieber Urbauer, Ramona J., Moskovitz, Jackob, Urbauer, Jeffrey L. and Seifert, Roland (2015) Different Roles of N-Terminal and C-Terminal Domains in Calmodulin for Activation of Bacillus anthracis Edema Factor. Toxins 7 (7), pp. 2598-2614.

Kagermeier, Nicole, Werner, Kristin, Keller, Max, Baumeister, Paul, Bernhardt, Günther, Seifert, Roland and Buschauer, Armin (2015) Dimeric carbamoylguanidine-type histamine H2 receptor ligands: A new class of potent and selective agonists. Bioorganic & Medicinal Chemistry 23 (14), pp. 3957-3969. Fulltext not available.

Arndt, Stephanie, Wacker, Eva, Dorn, Christoph

, Koch, Andreas, Saugspier, Michael, Thasler, W. E., Hartmann, Arndt, Bosserhoff, Anja-Katrin and Hellerbrand, Claus (2015) Enhanced expression of BMP6 inhibits hepatic fibrosis in non-alcoholic fatty liver disease. Gut 64 (6), pp. 973-981.

Huber, Stefan, Huettner, Johannes Philip, Hacker, Kristina, Bernhardt, Günther, König, Jörg and Buschauer, Armin (2015) Esters of bendamustine are by far more potent cytotoxic agents than the parent compound against human sarcoma and carcinoma cells. PLoS One 10 (7), PLoSe0133743.

Beermann, Silke, Bernhardt, Guenther, Seifert, Roland, Buschauer, Armin and Neumann, Detlef (2015) Histamine H1- and H4-receptor signaling cooperatively regulate MAPK activation. Biochemical Pharmacology 98 (3), pp. 432-439. Fulltext not available.

Strasser, Andrea and Buschauer, Armin (2015) Histaminrezeptoren. Pharmakon 3 (2), pp. 109-116. Fulltext not available.

Kirchhof, Susanne, Goepferich, Achim and Brandl, Ferdinand (2015) Hydrogels in ophthalmic applications. European Journal of Pharmaceutics and Biopharmaceutics 95, part B, pp. 227-238. Fulltext not available.

Radons, Jürgen, Falk, Werner and Dove, Stefan (2015) Identification of critical regions within the TIR domain of IL-1 receptor type I. The international journal of biochemistry & cell biology 68, pp. 15-20. Fulltext not available.

Keller, Max, Tränkle, Christian, She, Xueke, Pegoli, Andrea, Bernhardt, Günther, Buschauer, Armin and Read, Roger W. (2015) M2 subtype preferring dibenzodiazepinone-type muscarinic receptor ligands: effect of chemical homo-dimerization on orthosteric (and allosteric?) binding. Bioorganic & Medicinal Chemistry 23 (14), pp. 3970-3990. Fulltext not available.

Lübker, Carolin, Bieber-Urbauer, Ramona J., Moskovitz, Jackob, Dove, Stefan, Weisemann, Jasmin, Fedorova, Maria, Urbauer, Jeffrey L. and Seifert, Roland (2015) Membranous adenylyl cyclase 1 activation is regulated by oxidation of N- and C-terminal methionine residues in calmodulin. Biochemical Pharmacology 93 (2), pp. 196-209. Fulltext not available.

Strasser, Andrea, Wittmann, Hans-Joachim, Schneider, Erich H. and Seifert, Roland (2015) Modulation of GPCRs by monovalent cations and anions. Naunyn-Schmiedeberg's Archives of Pharmacology 388, pp. 363-380. Fulltext not available.

Wifling, David, Löffel, Karolin, Nordemann, Uwe, Strasser, Andrea, Bernhardt, Günther, Dove, Stefan, Seifert, Roland and Buschauer, Armin (2015) Molecular determinants for the high constitutive activity of the human histamine H4 receptor: Functional studies on orthologs and mutants. British Journal of Pharmacology 172, pp. 785-798. Fulltext not available.

Kaczor, Agnieszka, Guixa-Gonzalez, Ramon, Carrio, Pau, Poso, Antti, Dove, Stefan, Pastor, Manuel and Selent, Jana (2015) Multi-Component Protein - Protein Docking Based Protocol with External Scoring for Modeling Dimers of G Protein-Coupled Receptors. Molecular Informatics 34 (4), pp. 246-255. Fulltext not available.

Hennig, Robert, Ohlmann, Andreas, Staffel, Janina, Pollinger, Klaus, Haunberger, Alexandra, Breunig, Miriam, Schweda, Frank, Tamm, Ernst R. and Goepferich, Achim (2015) Multivalent nanoparticles bind the retinal and choroidal vasculature. Journal of Controlled Release 220 (Part A), pp. 265-274. Fulltext not available.

Hennig, Robert, Pollinger, Klaus, Tessmar, Joerg and Göpferich, Achim (2015) Multivalent targeting of AT1 receptors with angiotensin II-functionalized nanoparticles. Journal of Drug Targeting, pp. 1-9. Fulltext not available.

Keller, Max, Weiss, Stefan, Hutzler, Christoph, Kuhn, Kilian K., Mollereau, Catherine, Dukorn, Stefanie, Schindler, Lisa, Bernhardt, Günther, König, Burkhard and Buschauer, Armin (2015) N(omega)-carbamoylation of the argininamide moiety: an avenue to insurmountable NPY Y1 receptor antagonists and a radiolabeled selective high affinity molecular tool ([3H]UR-MK299) with extended residence time. Journal of Medicinal Chemistry 58 (22), pp. 8834-8849. Fulltext not available.

Hennig, Robert and Goepferich, Achim (2015) Nanoparticles for the treatment of ocular neovascularizations. European Journal of Pharmaceutics and Biopharmaceutics 95 (Part B), pp. 294-306. Fulltext not available.

Sun, Qiu, Heilmann, Jörg and König, Burkhard (2015) Natural phenolic metabolites with anti-angiogenic properties – a review from the chemical point of view. Beilstein Journal of Organic Chemistry 11, pp. 249-264.

Kirchhof, Susanne, Strasser, Andrea, Wittmann, Hans-Joachim, Messmann, Viktoria, Hammer, Nadine, Goepferich, Achim and Brandl, Ferdinand (2015) New insights into the cross-linking and degradation mechanism of Diels–Alder hydrogels. Journal of Materials Chemistry B 3, pp. 449-457.

Hammer, Nadine, Brandl, Ferdinand, Kirchhof, Susanne, Messmann, Viktoria and Goepferich, Achim (2015) Protein compatibility of selected cross-linking reactions for hydrogels. Macromol. Biosci. 15 (3), pp. 405-413. Fulltext not available.

Huber, Stefan, Antoni, Frauke, Schickaneder, Christian, Schickaneder, Helmut, Bernhardt, Günther and Buschauer, Armin (2015) Stabilities of neutral and basic esters of bendamustine in plasma compared to the parent compound: Kinetic investigations by HPLC. Journal of Pharmaceutical and Biomedical Analysis 104, pp. 137-143. Fulltext not available.

Reinartz, Michael T., Kälble, Solveig, Littmann, Timo, Ozawa, Takeaki, Dove, Stefan, Kaever, Volkhard, Wainer, Irving W. and Seifert, Roland (2015) Structure-bias relationships for fenoterol stereoisomers in six molecular and cellular assays at the β2-adrenoceptor. Naunyn-Schmiedeberg's archives of pharmacology 388 (1), pp. 51-65. Fulltext not available.

Untergehrer, Monika, Bücherl, Daniel, Wittmann, Hans-Joachim, Strasser, Andrea, Heilmann, Jörg and Jürgenliemk, Guido (2015) Structure-dependent deconjugation of flavonoid glucuronides by human beta-glucuronidase - in vitro and in silico analyses. Planta Med. 81 (12/13), pp. 1182-1189. Fulltext not available.

Huber, Stefan, Wege, Anja K., Bernhardt, Günther, Buschauer, Armin and Brockhoff, Gero (2015) Topotecan-induced ABCG2 expression in MCF-7 cells is associated with decreased CD24 and EpCAM expression and a loss of tumorigenicity. Cytometry A 87 (8), pp. 707-716. Fulltext not available.

Herrnberger, Leonie, Hennig, Robert, Kremer, Werner, Hellerbrand, Claus, Goepferich, Achim, Kalbitzer, Hans Robert and Tamm, Ernst R. (2014) Formation of Fenestrae in Murine Liver Sinusoids Depends on Plasmalemma Vesicle-Associated Protein and Is Required for Lipoprotein Passage. PLoS ONE 9 (12), e115005.

Cuboni, Serena, Devigny, Christian, Hoogeland, Bastiaan, Strasser, Andrea, Pomplun, Sebastian, Hauger, Barbara, Höfner, Georg, Wanner, Klaus, Eder, Matthias, Buschauer, Armin, Holsboer, Florian and Hausch, Felix (2014) Loratadine and analogs: Discovery and preliminary SAR of inhibitors of the amino acid transporter B0AT2. Journal of Medicinal Chemistry 57 (22), pp. 9473-9479. Fulltext not available.

Dulla, Balakrishna (2014) Synthesis and pharmacological characterization of novel N & O containing heterocyclic compounds as potential therapeutic agents. PhD, Universität Regensburg.

Baumeister, Paul (2014) Molecular tools for G-protein coupled receptors:
Synthesis, pharmacological characterization and [3H]-labeling of subtype-selective ligands for histamine H4 and NPY Y2 receptors. PhD, Universität Regensburg.

Hennig, Robert, Pollinger, Klaus, Veser, Anika, Breunig, Miriam and Goepferich, Achim (2014) Nanoparticle multivalency counterbalances the ligand affinity loss upon PEGylation. Journal of Controlled Release 194, pp. 20-27. Fulltext not available.

Haunschild, Gundula (2014) Nachweis und molekulare Charakterisierung EpCAM-positiver Zellen im Knochenmark von Mammakarzinom-Patientinnen. PhD, Universität Regensburg.

Slenczka, Alkwin, Premke, Tobias, Wirths, Eva-Maria, Pentlehner, Dominik, Lehnig, Rudolf, Richers, Ricarda and Vdovin, Alexander (2014) Microsolvation of Molecules in Superfluid Helium Nanodroplets Revealed by Means of Electronic Spectroscopy. Frontiers in Chemistry.

Schramm, Andrea (2014) Analyse renaler Funktionen der cGMP-abhängigen Proteinkinase II. PhD, Universität Regensburg.

Wittmann, Hans-Joachim, Seifert, Roland and Strasser, Andrea (2014) Mathematical analysis of the sodium sensitivity of the human histamine H3 receptor. In silico pharmacology 2.

Tauber, Philipp (2014) Untersuchungen zur Pathogenese von primärem Hyperaldosteronismus in neugeborenen Task3-/- Mäusen und adrenokortikalen Zellen mit KCNJ5-Mutation. PhD, Universität Regensburg.

Dove, Stefan (2014) Multivariate analysis of hydrophobic descriptors. ADMET & DMPK 2 (1), pp. 3-17.

Dove, Stefan, Danker, Kerstin Yvonne, Stasch, Johannes-Peter, Kaever, Volkhard and Seifert, Roland (2014) Structure/Activity Relationships of (M)ANT- and TNP-Nucleotides for Inhibition of Rat Soluble Guanylyl Cyclase alpha(1)beta(1). Molecular Pharmacology 85 (4), pp. 598-607. Fulltext not available.

Rothenhöfer, Martin (2014) Analytical approaches to the study of hyaluronan and hyaluronidases: Development and application of hyphenated chromatographic and electrophoretic methods. PhD, Universität Regensburg.

Bücherl, Daniel (2014) Isolation of kaempferol glycosides from Ginkgo biloba leaves and synthesis, identification and quantification of their major in vivo metabolites. PhD, Universität Regensburg.

Darras, Fouad, Pockes, Steffen

, Huang, Guozheng, Wehle, Sarah, Strasser, Andrea, Wittmann, Hans-Joachim, Nimczick, Martin, Sotriffer, Christoph and Decker, Michael (2014) Synthesis, biological evaluation, and computational studies of tri- and tetracyclic nitrogen-bridgehead compounds as potent dual-acting AChE inhibitors and hH3 receptor antagonists. ACS Chemical Neuroscience 5 (3), pp. 225-242. Fulltext not available.

Kremb, Stephan, Helfer, Markus and Kraus, Birgit (2014) Aqueous Extracts of the Marine Brown Alga Lobophora variegata Inhibit HIV-1 Infection at the Level of Virus Entry into Cells. PloS ONE 9, e103895.

Pollinger, Klaus, Hennig, Robert, Bauer, Stefanie, Breunig, Miriam, Tessmar, Joerg, Buschauer, Armin, Witzgall, Ralph and Göpferich, Achim (2014) Biodistribution of quantum dots in the kidney after intravenous injection. Journal of Nanoscience and Nanotechnology 14 (5), pp. 3313-3319. Fulltext not available.

Pannem, Rajeswara Rao, Dorn, Christoph

, Ahlqvist, Kristofer, Bosserhoff, Anja K., Hellerbrand, Claus and Massoumi, Ramin (2014) CYLD controls c-MYC expression through the JNK-dependent signaling pathway in hepatocellular carcinoma. Carcinogenesis 35 (2), pp. 461-468.

Hammer, Nadine, Brandl, Ferdinand, Kirchhof, Susanne and Goepferich, Achim (2014) Cleavable carbamate linkers for controlled protein delivery from hydrogels. Journal of Controlled Release 183, pp. 67-76. Fulltext not available.

Schweizer, Daniel, Serno, Tim and Goepferich, Achim (2014) Controlled release of therapeutic antibody formats. European Journal of Pharmaceutics and Biopharmaceutics 88 (2), pp. 291-309. Fulltext not available.

Pannem, Rajeswara R., Dorn, Christoph

, Hellerbrand, Claus and Massoumi, Ramin (2014) Cylindromatosis gene CYLD regulates hepatocyte growth factor expression in hepatic stellate cells through interaction with histone deacetylase 7. Hepatology 60 (3), pp. 1066-1081.

Dorn, Christoph

, Engelmann, Julia C., Saugspier, Michael, Koch, Andreas, Hartmann, Arndt, Müller, Martina, Spang, Rainer, Bosserhoff, Anja and Hellerbrand, Claus (2014) Increased expression of c-Jun in nonalcoholic fatty liver disease. Laboratory Investigation 94 (4), pp. 394-408. Fulltext not available.

Wolter, Sabine, Dove, Stefan, Golombek, Marina, Schwede, Frank and Seifert, Roland (2014) N4-monobutyryl-cCMP activates PKA RIα and PKA RIIα more potently and with higher efficacy than PKG Iα in vitro but not in vivo. Naunyn-Schmiedeberg's archives of pharmacology 387 (12), pp. 1163-1175. Fulltext not available.

Werner, Kristin, Neumann, Detlef, Buschauer, Armin and Seifert, Roland (2014) No evidence for histamine H4-receptor in human monocytes. Journal of Pharmacology and Experimental Therapeutics 351 (3), pp. 519-526. Fulltext not available.

Wager, Eva, Wittmann, Hans-Joachim, Elz, Sigurd and Strasser, Andrea (2014) Pharmacological profile of astemizole-derived compounds at the histamine H1 and H4 receptor - H1/H4 receptor selectivity. Naunyn-Schmiedeberg's Archives of Pharmacology 387, pp. 235-250. Fulltext not available.

Luschmann, Christoph, Tessmar, Joerg, Schoeberl, Simon, Strauss, O., Luschmann, Karl and Goepferich, Achim (2014) Self-assembling colloidal system for the ocular administration of cyclosporine A. Cornea 33 (1), pp. 77-81. Fulltext not available.

Wittmann, Hans-Joachim, Seifert, Roland and Strasser, Andrea (2014) Sodium binding to hH3R and hH4R - a molecular modelling study. Journal of Molecular Modeling 20, p. 2394. Fulltext not available.

Geyer, Roland, Kaske, Melanie, Baumeister, Paul and Buschauer, Armin (2014) Synthesis and functional characterization of imbutamine analogs as histamine H3 and H4 receptor ligands. Archiv der Pharmazie (Weinheim, Germany) 347 (2), pp. 77-88. Fulltext not available.

Geyer, Roland, Igel, Patrick, Kaske, Melanie, Elz, Sigurd and Buschauer, Armin (2014) Synthesis, SAR and selectivity of 2-acyl- and 2-cyano-1-hetarylalkyl-guanidines at the four histamine receptor subtypes: a bioisosteric approach. MedChemComm 5 (1), pp. 72-81. Fulltext not available.

Endlich, Nicole, Simon, Ole, Goepferich, Achim, Wegner, Henny, Moeller, Marcus J., Rumpel, Elisabeth, Kotb, Ahmed and Endlich, Karlhans (2014) Two-Photon Microscopy Reveals Stationary Podocytes in Living Zebrafish Larvae. Journal of the American Society of Nephrology 25 (4), pp. 681-686. Fulltext not available.

Schickaneder, Helmut, Buschauer, Armin, Bernhardt, Günther, Schickaneder, Christian, Limmert, Michael, Huber, Stefan, Lubbe, Mathias and Hofmeier, Harald (2013) Esters of bendamustine and related compounds, and medical use thereof. Fulltext not available.

Brunner, Elisabeth (2013) Einsatz von Everolimus zur Prävention der chronischen Abstoßung nach orthotoper unilateraler Lungentransplantation in der Ratte. PhD, Universität Regensburg.

Schmidt, Sebastian (2013) Phytochemische und pharmakologische in vitro Untersuchungen zu Hypericum empetrifolium WILLD. PhD, Universität Regensburg.

Loth, Tina, Hennig, Robert, Kascholke, Christian, Hötzel, Rudi and Hacker, Michael (2013) Reactive and stimuli-responsive maleic anhydride containing macromers–multi-functional cross-linkers and building blocks for hydrogel fabrication. Reactive and Functional Polymers 73 (11), pp. 1480-1492. Fulltext not available.

Sadek, Bassem, Alisch, Rudi, Buschauer, Armin and Elz, Sigurd (2013) Synthesis and dual histamine H1 and H2 receptor antagonist activity of cyanoguanidine derivatives. Molecules 18 (11), pp. 14186-14202.

Dove, Stefan and Buschauer, Armin (2013) G-Protein-gekoppelte Rezeptoren: „Sinnesorgane“ der Zellen. Blick in die Wissenschaft 22 (28), pp. 3-9. Fulltext not available.

Schreeb, Annemarie, Łażewska, Dorota, Dove, Stefan, Buschauer, Armin, Kieć-Kononiwcz, Katarzyna and Stark, Holger (2013) 2. Histamine H4 receptor ligands. In: Stark, Holger, (ed.) Histamine H4 receptor: a novel drug target for immunoregulation and inflammation. Versita, London, pp. 21-62. ISBN 9788376560564. Fulltext not available.

Stöckl, Sabine (2013) Der Einfluss von Sox9 auf Zellvitalität und Differenzierungspotential von adulten mesenchymalen Stammzellen. PhD, Universität Regensburg.

Keller, Max, Kaske, Melanie, Holzammer, Tobias, Bernhardt, Günther and Buschauer, Armin (2013) Dimeric argininamide-type neuropeptide Y receptor antagonists: chiral discrimination between Y1 and Y4 receptors. Bioorganic and Medicinal Chemistry 21 (21), pp. 6303-6322. Fulltext not available.

Weisser, Roland (2013) Planung einer Studie zur Etablierung des therapeutischen Referenzbereichs der Wirkstoffkonzentration eines Antidementivums. PhD, Universität Regensburg.

Berlicki, Lukasz, Kaske, Melanie, Gutierrez-Abad, Raquel, Bernhardt, Günther, Illa, Ona, Ortuño, Rosa, Cabrele, Chiara, Buschauer, Armin and Reiser, Oliver (2013) Replacement of Thr32 and Gln34 in the C-terminal neuropeptide Y fragment 25-36 by cis-cyclobutane- and cis-cyclopentane β-amino acids shifts selectivity toward the Y4 receptor. Journal of Medicinal Chemistry 56 (21), pp. 8422-8431. Fulltext not available.

Nordemann, Uwe, Wifling, David, Schnell, David, Bernhardt, Günther, Stark, Holger, Seifert, Roland and Buschauer, Armin (2013) Luciferase reporter gene assay on human, murine and rat histamine H4 receptor orthologs: correlations and discrepancies between distal and proximal readouts. PLoS One 8 (9), e73961.

Bauer, Stefanie, Ochoa Puentes, Cristian, Sun, Qiu, Bause, Manuel, Bernhardt, Günther, König, Burkhard and Buschauer, Armin (2013) Quinoline carboxamide-type ABCG2 modulators: Indole and quinoline moieties as anilide replacements. ChemMedChem 8 (11), pp. 1773-1778. Fulltext not available.

Holzammer, Tobias (2013) Homology modeling, molecular dynamics simulations and site-directed mutagenesis of histamine H2 receptors. PhD, Universität Regensburg.

Kirchhof, Susanne, Brandl, Ferdinand, Hammer, Nadine and Göpferich, Achim (2013) Investigation of the Diels–Alder reaction as a cross-linking mechanism for degradable poly(ethylene glycol) based hydrogels. Journal of Materials Chemistry B 1 (37), pp. 4855-4864. Fulltext not available.

Kaske, Melanie (2013) In search for potent and selective NPY Y4 receptor ligands: acylguanidines, argininamides and peptide analogs. PhD, Universität Regensburg.

Brunskole Hummel, Irena, Kälble, Solveig, Burhenne, Heike, Reinartz, Michael T., Schwede, Frank, Buschauer, Armin and Seifert, Roland (2013) Dissociations in the effects of beta2-adrenergic receptor agonists on cAMP formation and superoxide production in human neutrophils: Support for the concept of functional selectivity. PLoS One 8 (5), e64556.

Zölls, Sarah, Gregoritza, Manuel, Tantipolphan, Ruedeeporn, Wiggenhorn, Michael, Winter, Gerhard, Friess, Wolfgang and Hawe, Andrea (2013) How Subvisible Particles Become Invisible - Relevance of the Refractive Index for Protein Particle Analysis. Journal of Pharmaceutical Sciences 102 (5), pp. 1434-1446. Fulltext not available.

Kees, Martin Georg, Schaeftlein, André, Haeberle, Helene Anna, Kees, Frieder K., Kloft, Charlotte and Heininger, Alexandra (2013) Population pharmacokinetics and pharmacodynamic evaluation of intravenous and enteral moxifloxacin in surgical intensive care unit patients. The Journal of antimicrobial chemotherapy. Fulltext not available.

Ochoa-Puentes, Cristian, Bauer, Stefanie, Kühnle, Matthias, Bernhardt, Günther, Buschauer, Armin and König, Burkhard (2013) Benzanilide – Biphenyl Replacement: A Bioisosteric Approach to Quinoline Carboxamide-type ABCG2 Modulators. ACS Medicinal Chemistry Letters 4 (4), pp. 393-396. Fulltext not available.

Pluym, Nikola, Baumeister, Paul, Keller, Max, Bernhardt, Günther and Buschauer, Armin (2013) [3H]UR-PLN196: A Selective Nonpeptide Radioligand and Insurmountable Antagonist for the Neuropeptide Y Y2 Receptor. ChemMedChem 8 (4), pp. 587-593. Fulltext not available.

Miller, Tobias (2013) Polymeric micelles for solubilization and targeting of hydrophobic drugs. PhD, Universität Regensburg.

Seifert, Roland, Strasser, Andrea, Schneider, Erich H., Neumann, Detlef, Dove, Stefan and Buschauer, Armin (2013) Molecular and cellular analysis of human histamine receptor subtypes. Trends in Pharmacological Sciences 34 (1), pp. 33-58. Fulltext not available.

Strasser, Andrea, Wittmann, Hans-Joachim, Buschauer, Armin, Schneider, Erich H. and Seifert, Roland (2013) Species-dependent activities of GPCR ligands: Lessons from histamine receptor orthologs. Trends in Pharmacological Sciences 34 (1), pp. 13-32. Fulltext not available.

Krautbauer, Sabrina, Wanninger, Josef, Eisinger, Kristina, Hader, Yvonne, Beck, Michael, Kopp, Andrea, Schmid, Andreas, Weiss, Thomas S., Dorn, Christoph

and Buechler, Christa (2013) Chemerin is highly expressed in hepatocytes and is induced in non-alcoholic steatohepatitis liver. Experimental and Molecular Pathology 95 (2), pp. 199-205. Fulltext not available.

Luschmann, Christoph, Tessmar, Joerg, Schoeberl, Simon, Framme, Carsten, Luschmann, Karl and Goepferich, Achim (2013) Developing an in situ nanosuspension: A novel approach towards the efficient administration of poorly soluble drugs at the anterior eye. European Journal of Pharmaceutical Sciences 50 (3-4), pp. 385-392. Fulltext not available.

Miller, Tobias, van Colen, G., Sander, B., Golas, M., Uezguen, Senta, Weigandt, Markus and Goepferich, Achim (2013) Drug Loading of Polymerics Micelles. Pharmaceutical Research 30 (2), pp. 484-595. Fulltext not available.

Dietrich, P., Moleda, Lukas, Kees, Frieder K., Müller, M., Straub, R. H., Hellerbrand, C. and Wiest, R. (2013) Dysbalance in sympathetic neurotransmitter release and action in cirrhotic rats: impact of exogenous neuropeptide Y. Journal of hepatology 58 (2), pp. 254-261. Fulltext not available.

Ferstl, Matthias, Drechsler, Markus, Rachel, Reinhard, Rischer, M., Engel, J., Backofen, Michael and Goepferich, Achim (2013) Impact of Polyelectrolyte Structure on the Shape of Nanoassemblies with Cationic Peptides. European Journal of Pharmaceutical Sciences 102, pp. 2599-2607. Fulltext not available.

Seifert, Roland and Dove, Stefan (2013) Inhibitors of Bacillus anthracis edema factor. Pharmacology & Therapeutics 140 (2), pp. 200-212. Fulltext not available.

Mueller, M., Blunk, Torsten, Appel, Bernhard, Maschke, Angelika, Goepferich, Achim and Zellner, J. (2013) Insulin is essential for in vitro chondrogenesis of mesenchymal progenitor cells and influences chondrogenesis in a dose-dependent manner. International orthopaedics 37 (1), pp. 153-158. Fulltext not available.

Wurster, Eva-Christina, Elbakry, Asmaa, Goepferich, Achim and Breunig, Miriam (2013) Layer-by-layer assembled gold nanoparticles for the delivery of nucleic acids. In: Nanotechnology for Nucleic Acid Delivery : Methods and Protocols. Methods in Molecular Biology, 948. Humana Press; Springer, Totowa, NJ, pp. 171-182. ISBN 978-1-62703-139-4 (print), 978-1-627-03140-0 (online). Fulltext not available.

Pollinger, Klaus, Hennig, Robert, Ohlmann, Andreas, Fuchshofer, R., Wenzel, Rebecca and Breunig, Miriam (2013) Ligand-functionalized nanoparticles target endothelial cells in retinal capillaries after systemic application. Proceedings of the National Academy of Sciences of the United States of America (PNAS) 25, pp. 6115-6120. Fulltext not available.

Strasser, Andrea and Wittmann, Hans-Joachim (2013) Modelling of GPCRs - A Practical Handbook. Springer. Fulltext not available.

Strasser, Andrea and Wittmann, Hans-Joachim (2013) Molecular modelling studies give hint for the existence of a symmetric hb2R-Gabg-homodimer. J Mol Model 19, pp. 4443-4457. Fulltext not available.

Hozsa, Constantin, Breunig, Miriam and Goepferich, Achim (2013) Monitoring the Degradation of Reduction-Sensitive Gene Carriers with Fluorescence Spectroscopy and Flow Cytometry. Methods in Molecular Biology 991, pp. 171-184. Fulltext not available.

Luschmann, Christoph, Herrmann, W., Strauss, Olaf, Luschmann, Karl and Goepferich, Achim (2013) Ocular delivery systems for poorly soluble drugs: An in-vivo evaluation. International Journal of Pharmaceutics 455 (1-2), pp. 331-337. Fulltext not available.

Schweizer, Daniel, Voitier, I., Heier, A., Serno, Tim, Goepferich, Achim and et, al. (2013) Pharmacokinetics, biocompatibility and bioavailability of a controlled release monoclonal antibody formulation. Journal of Controlled Release 172 (3), pp. 975-982. Fulltext not available.

Miller, Tobias, Breyer, S., van Colen, G., Mier, W., Haberkorn, U., Geissler, S., Voss, S., Weigandt, Markus and Goepferich, Achim (2013) Premature drug release of polymeric micelles and its effects on tumor targeting. International Journal of Pharmaceutics 445 (1-2), pp. 117-124. Fulltext not available.

Schweizer, Daniel, Schoenhammer, K., Jahn, M. and Goepferich, Achim (2013) Protein-Polyanion Interactions for the Controlled Release of Monoclonal Antibodies. Biomacromolecules 14 (1), pp. 75-83. Fulltext not available.

Holzhauser, C., Liebl, Renate, Goepferich, Achim, Wagenknecht, Hans-Achim and Breunig, Miriam (2013) RNA “Traffic Lights”: An Analytical Tool to Monitor siRNA Integrity. ACS chemical biology 8, pp. 890-894. Fulltext not available.

Nordemann, Uwe (2013) Radioligand binding and reporter gene assays for histamine H3 and H4 receptor species orthologs. PhD, Universität Regensburg.

Bodensteiner, Julian, Baumeister, Paul, Geyer, Roland, Buschauer, Armin and Reiser, Oliver (2013) Synthesis and pharmacological characterization of new tetrahydrofuran based compounds as conformationally constrained histamine receptor ligands. Organic & biomolecular chemistry 11 (24), pp. 4040-4055.

Göpferich, Achim (2013) To pause a moment. European Journal of Pharmaceutics and Biopharmaceutics 85 (3), p. 328. Fulltext not available.

Dorn, Christoph

, Massinger, Sabine, Wuzik, Andreas, Heilmann, Jörg and Hellerbrand, Claus (2013) Xanthohumol suppresses inflammatory response to warm ischemia–reperfusion induced liver injury. Experimental and Molecular Pathology 94 (1), pp. 10-16. Fulltext not available.

Wolfertstetter, Stefanie, Huettner, Johannes Philip and Schlossmann, Jens (2013) cGMP-dependent Protein Kinase Inhibitors in Health and Disease. Pharmaceuticals 6, pp. 269-286.

Ertel, Miriam, Bernhardt, Günther, Nink, Jörg and Buschauer, Armin (2012) Novel prodrugs of (1S,9S)-9-[[(1S)-1-carboxy-3-phenylpropyl]amino]octahydro-10-oxo-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid and their use in transdermal therapeutic systems. Fulltext not available.

Memminger, Martin, Keller, Max, Lopuch, Miroslaw, Pop, Nathalie, Bernhardt, Günther, von Angerer, Erwin and Buschauer, Armin (2012) The Neuropeptide Y Y1 receptor: a diagnostic marker? Expression in MCF-7 breast cancer cells is down-regulated by antiestrogens in vitro and in xenografts. PLoS ONE 7 (12), e51032.

Löber, Stefan, Hübner, Harald, Buschauer, Armin, Sanna, Fabrizio, Argiolas, Antonio, Melis, Maria Rosaria and Gmeiner, Peter (2012) Novel azulene derivatives for the treatment of erectile dysfunction. Bioorganic & medicinal chemistry letters 22 (23), pp. 7151-7154. Fulltext not available.

Saugspier, Michael Sebastian (2012) Analysis of the anti-fibrotic effects of hop bitter acids on hepatic stellate cells and their anti-tumorigenic effects on hepatocellular carcinoma cells. PhD, Universität Regensburg.

Rothenhöfer, Martin, Scherübl, Rosmarie, Bernhardt, Günther, Heilmann, Jörg and Buschauer, Armin (2012) Qualitative and quantitative analysis of hyaluronan oligosaccharides with high performance thin layer chromatography using reagent-free derivatization on amino-modified silica and electrospray ionization-quadrupole time-of-flight mass spectrometry coupling on normal phase. Journal of chromatography. A 1248, pp. 169-77. Fulltext not available.

Ertel, Miriam (2012) Ambivalence of drug metabolism: Exploration of cilazapril and candesartan prodrugs for transdermal delivery and search for toxic reactive intermediates of N(G)-acylated hetarylpropylguanidines. PhD, Universität Regensburg.

Hild, Wolfgang (2012) Cellular nanoparticle delivery by G-protein coupled receptors. PhD, Universität Regensburg.

Reher, Till M., Neumann, Detlef, Buschauer, Armin and Seifert, Roland (2012) Incomplete activation of human eosinophils via the histamine H(4)-receptor: Evidence for ligand-specific receptor conformations. Biochemical Pharmacology 84 (2), pp. 192-203. Fulltext not available.

Seifert, Roland and Dove, Stefan (2012) 3/14. Molecular analysis of agonist stereoisomers at β2-adrenoceptors. In: Jozwiak, Krzysztof and Lough, W. John and Wainer, Irving W., (eds.) Drug stereochemistry : Analytical methods and pharmacology. 3. ed. Informa Healthcare, New York, pp. 274-293. ISBN 9781420092387. Fulltext not available.

Deml, Karl-Friedrich (2012) Interaktionen von Histamin H1-Rezeptoragonisten und
–antagonisten mit dem humanen Histamin H4-Rezeptor. PhD, Universität Regensburg.

Birnkammer, Tobias, Spickenreither, Anja, Brunskole, Irena, Lopuch, Miroslaw, Kagermeier, Nicole, Bernhardt, Günther, Dove, Stefan, Seifert, Roland, Elz, Sigurd and Buschauer, Armin (2012) The bivalent ligand approach leads to highly potent and selective acylguanidine-type histamine H2 receptor agonists. Journal of Medicinal Chemistry 55 (3), pp. 1147-1160. Fulltext not available.

Dorn, Christoph

, Heilmann, Jörg and Hellerbrand, Claus (2012) Protective effect of xanthohumol on toxin-induced liver inflammation and fibrosis. International Journal of Clinical and Experimental Pathology 5 (1), pp. 29-36.

Bauhuber, Sonja, Liebl, Renate, Tomasetti, Luise, Rachel, Reinhard, Goepferich, Achim and Breunig, Miriam (2012) A library of strictly linear poly(ethylene glycol)-poly(ethylene imine) diblock coploymers to perform structure-function relationship on non-viral gene carriers. Journal of Controlled Release 162, pp. 446-455. Fulltext not available.

Miller, Tobias, Hiller, Alexandra, Uezguen, Senta, Weigandt, Markus and Goepferich, Achim (2012) Analysis of Immediate Stress Mechanisms upon Injection of Polymeric Micelles and Related Colloidal Drug Carriers. Biomacromolecules 13 (6), pp. 1707-1718. Fulltext not available.

Miller, Tobias, Rachel, Reinhard, Besheer, Ahmed, Uezguen, Senta, Weigand, Markus and Göpferich, Achim (2012) Comparative Investigations on In Vitro Serum Stability of Polymeric Micelle Formulations. Pharmaceutical Research 29 (2), pp. 448-459. Fulltext not available.

Posavec, Damir, Zabel, Manfred, Bogner, Udo, Bernhardt, Günther and Knör, Günther (2012) Functionalized derivatives of 1,4-dimethylnaphthalene as precursors for biomedical applications: synthesis, structures, spectroscopy and photochemical activation in the presence of dioxygen. Organic & biomolecular chemistry 10 (35), pp. 7062-7069.

Saugspier, Michael, Dorn, Christoph

, Thasler, Wolfgang E., Gehrig, Manfred, Heilmann, Jörg and Hellerbrand, Claus (2012) Hop bitter acids exhibit anti-fibrogenic effects on hepatic stellate cells in vitro. Experimental and Molecular Pathology 92 (2), pp. 222-228. Fulltext not available.

Saugspier, Michael, Dorn, Christoph

, Czech, Barbara, Gehrig, Manfred, Heilmann, Jörg and Hellerbrand, Claus

(2012) Hop bitter acids inhibit tumorigenicity of hepatocellular carcinoma cells in vitro. Oncology Reports 28 (4), pp. 1423-1428. Fulltext not available.

Appl, Heidrun, Holzammer, Tobias, Dove, Stefan, Haen, Ekkehard, Strasser, Andrea and Seifert, Roland (2012) Interactions of recombinant human histamine H₁R, H₂R, H₃R, and H₄R receptors with 34 antidepressants and antipsychotics. Naunyn-Schmiedeberg's archives of pharmacology 385 (2), pp. 145-170. Fulltext not available.

Pollinger, Klaus, Hennig, Robert, Breunig, Miriam, Teßmar, Jörg, Ohlmann, Andreas, Tamm, Ernst R., Witzgall, Ralph and Goepferich, Achim (2012) Kidney Podocytes as Specific Targets for cyclo(RGDfC)-Modified Nanoparticles. Small 8, pp. 3368-3375. Fulltext not available.

Elbakry, Asmaa Mohamed, Wurster, Eva-Christina, Zaky, Alaa, Liebl, Renate, Schindler, Edith, Bauer-Kreisel, Petra, Blunk, Torsten, Rachel, Reinhard, Goepferich, Achim and Breunig, Miriam (2012) Layer-by-Layer Coated Gold Nanoparticles: Size-Dependent Delivery of DNA into Cells. Small 8 (24), pp. 3847-3856. Fulltext not available.

Heller, Anne, Fischer, Lorenz H., Wolfbeis, Otto S. and Göpferich, Achim (2012) Long time monitoring of the respiratory activity of isolated mitochondria. Experimental Cell Research 318 (14), pp. 1667-1672. Fulltext not available.

Kees, Martin G., Steinke, T., Moritz, S., Rupprecht, K., Paulus, E. M., Kees, Frieder K., Bucher, M. and Faerber, L. (2012) Omeprazole impairs the absorption of mycophenolate mofetil but not of enteric-coated mycophenolate sodium in healthy volunteers. Journal of clinical pharmacology 52 (8), pp. 1265-1272. Fulltext not available.

Justinger, Christoph, Schilling, Martin K., Kees, Martin G., Kauffels, Anne, Hirschmann, Katrin, Kopp, Berit, Kees, Frieder K. and Kollmar, Otto (2012) Penetration of moxifloxacin into liver tissue. International journal of antimicrobial agents 39 (6), pp. 505-509. Fulltext not available.

Bernat, Viachaslau, Heinrich, Markus, Baumeister, Paul, Buschauer, Armin and Tschammer, Nuska (2012) Synthesis and application of the first radioligand targeting the allosteric binding pocket of chemokine receptor CXCR3. ChemMedChem 7 (8), pp. 1481-1489. Fulltext not available.

Heller, Anne, Brockhoff, Gero and Goepferich, Achim (2012) Targeting drugs to mitochondria. European Journal of Pharmaceutics and Biopharmaceutics 82, pp. 1-18. Fulltext not available.

Seifert, Roland and Dove, Stefan (2012) Towards selective inhibitors of adenylyl cyclase toxin from Bordetella pertussis. Trends in microbiology 20 (7), pp. 343-351. Fulltext not available.

Kaftan, Holger, Goepferich, Achim, Kaftan, Silke and Hosemann, Werner (2012) Two different techniques to facilitate reconstruction of the long incus process with bone cement: a feasibility study in human cadaveric temporal bones. European Archives of Oto-Rhino-Laryngology 269, pp. 1431-1435. Fulltext not available.

Strasser, Andrea and Wittmann, Hans-Joachim (2012) hb2R-Gas-complex: Prediction versus crystal structure - How valuable are predictions based on molecular modelling studies? Journal of Molecular Modeling : J Mol Model 18, pp. 3439-3444. Fulltext not available.

Brunskole, Irena (2011) Molecular and cellular analysis of aminergic G protein-coupled receptors: histamine H2, H4 and β2-adrenergic receptors, a scientific paradigm. PhD, Universität Regensburg.

Geyer, Roland (2011) Hetarylalkyl(aryl)cyanoguanidines as histamine H4 receptor ligands: Synthesis, chiral separation, pharmacological characterization, structure-activity and -selectivity relationships. PhD, Universität Regensburg.

Lopuch, Miroslaw (2011) Investigations on neuropeptide Y and histamine receptors by fluorescence-based and radiochemical methods. PhD, Universität Regensburg.

Klein, Matthias S., Dorn, Christoph

, Saugspier, Michael Sebastian, Hellerbrand, Claus, Oefner, Peter J. and Gronwald, Wolfram (2011) Discrimination of steatosis and NASH in mice using nuclear magnetic resonance spectroscopy. Metabolomics 7 (2), pp. 237-246. Fulltext not available.

Erdorf, Miriam and Seifert, Roland (2011) Pharmacological characterization of adenylyl cyclase isoforms in rabbit kidney membranes. Naunyn-Schmiedeberg's Archives of Pharmacology 383 (4), pp. 357-372. Fulltext not available.

Kellermann, K., Dertinger, N., Blobner, M., Kees, Frieder, Kochs, E. F. and Jungwirt, B. (2011) Perioperative moxifloxacin treatment in rats subjected to deep hypothermic circulatory arrest: reduction in cerebral inflammation but without improvement in cognitive performance. Journal of Thoracic and Cardiovascular Surgery 141 (3), pp. 796-802. Fulltext not available.

Schinner, Elisabeth, Salb, Katharina and Schlossmann, Jens (2011) Signaling via IRAG is essential for NO/cGMP-dependent inhibition of platelet activitation. Platelets. Fulltext not available.

Gäbele, Erwin, Dostert, Karin, Dorn, Christoph

, Patsenker, Eleonora, Stickel, Felix and Hellerbrand, Claus (2011) A New Model of Interactive Effects of Alcohol and High-Fat Diet on Hepatic Fibrosis. Alcoholism: Clinical and Experimental Research 35 (7), pp. 1361-1367. Fulltext not available.

Wanninger, Josef, Neumeier, Markus, Bauer, Sabrina, Weiss, Thomas S., Eisinger, Kristina, Walter, Roland, Dorn, Christoph

, Hellerbrand, Claus, Schäffler, Andreas and Buechler, Christa (2011) Adiponectin induces the transforming growth factor decoy receptor BAMBI in human hepatocytes. FEBS Letters 585 (9), pp. 1338-1344. Fulltext not available.

Osman, Shaaban, Brandl, Ferdinand, Zayed, Gamal, Teßmar, Jörg and Göpferich, Achim (2011) Cyclodextrin based hydrogels: Inclusion complex formation and micellization of adamantane and cholesterol grafted polymers. Polymer 52 (21), pp. 4806-4812. Fulltext not available.

Kirovski, Georgi, Dorn, Christoph

, Huber, Hanna, Moleda, Lukas, Niessen, Catrin, Wobser, Hella, Schacherer, Doris, Buechler, Christa, Wiest, Reiner and Hellerbrand, Claus (2011) Elevated systemic monocyte chemoattractrant protein-1 in hepatic steatosis without significant hepatic inflammation. Experimental and Molecular Pathology 91 (3), pp. 780-783. Fulltext not available.

Schaedlich, A., Rose, C., Kuntsche, J., Caysa, H., Mueller, T., Goepferich, Achim and Maeder, K. (2011) How Stealthy are PEG-PLA Nanoparticles? An NIR In Vivo Study Combined with Detailed Size Measurements. Pharmaceutical Research 28 (8), pp. 1995-2007. Fulltext not available.

Wittmann, Hans-Joachim, Seifert, Roland and Strasser, Andrea (2011) Influence of the N-terminus and the E2-loop onto the binding kinetics of the antagonist mepyramine and the partial agonist phenoprodifen to H1R. Biochemical Pharmacology 12, pp. 1910-1918. Fulltext not available.

Wanninger, Josef, Walter, Roland, Bauer, Sabrina, Eisinger, Kristina, Schäffler, Andreas, Dorn, Christoph

, Weiss, Thomas S., Hellerbrand, Claus and Buechler, Christa (2011) MMP-9 activity is increased by adiponectin in primary human hepatocytes but even negatively correlates with serum adiponectin in a rodent model of non-alcoholic steatohepatitis. Experimental and Molecular Pathology 91 (2), pp. 603-607. Fulltext not available.

Wagner, Eva, Wittmann, Hans-Joachim, Elz, Sigurd and Strasser, Andrea (2011) Mepyramine-JNJ7777120-hybrid compounds show high affinity to hH1R, but low affinity to hH4R. Bioorganic & Medicinal Chemistry Letters 21, pp. 6274-9280. Fulltext not available.

Wittmann, Hans-Joachim, Elz, Sigurd, Seifert, Roland and Strasser, Andrea (2011) Na-methylated phenylhistamines exhibit affinity to the hH4R - a pharmacological and molecular modelling study. Naunyn Schmiedeberg's Arch Pharmacol 384, pp. 287-299. Fulltext not available.

Ferstl, Matthias, Strasser, Andrea, Wittmann, Hans-Joachim, Drechsler, Markus, Rischer, M., Engl, J. and Goepferich, Achim (2011) Nanofibres Resulating from Cooperative Electrostatic and Hydrophobic Interactions between Peptides and Polyelectrolytes of Opposite Charge. Langmuir 27, pp. 14450-14459. Fulltext not available.

Henkel, Janin, Gärtner, Daniela, Dorn, Christoph

, Hellerbrand, Claus, Schanze, Nancy, Elz, Sheila R. and Püschel, Gerhard P. (2011) Oncostatin M produced in Kupffer cells in response to PGE2: possible contributor to hepatic insulin resistance and steatosis. Laboratory Investigation 91 (7), pp. 1107-1117. Fulltext not available.

Kees, Martin G., Weber, Susanne, Kees, Frieder K. and Horbach, Thomas (2011) Pharmacokinetics of moxifloxacin in plasma and tissue of morbidly obese patients. The Journal of antimicrobial chemotherapy 66 (10), pp. 2330-2335. Fulltext not available.

Patsenker, Eleonora, Schneider, Vreni, Ledermann, Monika, Saegesser, Hans, Dorn, Christoph

, Hellerbrand, Claus and Stickel, Felix (2011) Potent antifibrotic activity of mTOR inhibitors sirolimus and everolimus but not of cyclosporine A and tacrolimus in experimental liver fibrosis. Journal of Hepatology 55 (2), pp. 388-398. Fulltext not available.

Bauer, Sabrina, Wanninger, Josef, Schmidhofer, Sandra, Weigert, Johanna, Neumeier, Markus, Dorn, Christoph

, Hellerbrand, Claus, Zimara, Nicole, Schäffler, Andreas, Aslanidis, Charalampos and Buechler, Christa (2011) Sterol Regulatory Element-Binding Protein 2 (SREBP2) Activation after Excess Triglyceride Storage Induces Chemerin in Hypertrophic Adipocytes. Endocrinology 152 (1), pp. 26-35. Fulltext not available.

Schaedlich, A., Caysa, H., Mueller, T., Tenambergen, F., Rose, Cornelia, Goepferich, Achim, Kuntsche, J. and Maeder, K. (2011) Tumor Accumulation of NIR Fluorescent PEG PLA Nanoparticles: Impact of Particle Size and Human Xenograft Tumor Model. ACS Nano 5, pp. 8710-8720. Fulltext not available.

Kees, M. G., Hilpert, J. W., Gnewuch, C., Kees, F. and Voegeler, S. (2010) Clearance of vancomycin during continuous infusion in intensive care unit patients: correlation with measured and estimated creatinine clearance and serum cystatin C. International Journal of Antimicrobial Agents 36 (6), pp. 545-548. Fulltext not available.

Schnell, David, Strasser, Andrea and Seifert, Roland (2010) Comparison of the pharmacological properties of human and rat histamine H(3)-receptors. Biochemical Pharmacology 80 (9), pp. 1437-1449. Fulltext not available.

Mathar, I., Vennekens, R., Meissner, M., Kees, Frieder K., Van der Mieren, G. and Camacho Londono, J. (2010) Increased catecholamine secretion contributes to hypertension in TRPM4-deficient mice. The Journal of Clinical Investigation 120 (9), pp. 3267-3279. Fulltext not available.

Desch, Matthias, Schinner, Elisabeth, Kees, Frieder K., Hofmann, F., Seifert, Roland and Schlossmann, Jens (2010) Cyclic cytidine 3´,5´-monophosphate (cCMP) signals via cGMP kinase I. FEBS Letters 584 (18), pp. 3979-3984. Fulltext not available.

Kirovski, Georgi, Gäbele, Erwin, Dorn, Christoph

, Moleda, Lukas, Niessen, Christoph, Weiss, Thomas S., Wobser, Hella, Schacherer, Doris, Buechler, Christa, Wasmuth, Hermann E. and Hellerbrand, Claus (2010) Hepatic steatosis causes induction of the chemokine RANTES in the absence of significant hepatic inflammation. International Journal of Clinical and Experimental Pathology 3 (7), pp. 675-680.

Schneider, E. H., Strasser, Andrea, Thurmond, R. L. and Seifert, Roland (2010) Structural requirements for inverse agonism and neutral antagonism of indole-, benzimidazole-, and thienopyrrole-derived histamine H4 receptor ligands. Journal of Pharmacology and Experimental Therapeutics 334 (2), pp. 513-521. Fulltext not available.

Hild, Wolfgang, Pollinger, Klaus, Caporale, Andrea, Cabrele, Chiara, Keller, Max, Pluym, Nicola, Buschauer, Armin

, Rachel, Reinhard

, Tessmar, Joerg, Breunig, Miriam and Goepferich, Achim

(2010) G protein-coupled receptors function as logic gates for nanoparticle binding and cell uptake. Proceedings of the National Academy of Sciences USA: PNAS 107 (23), pp. 10667-10672. Fulltext not available.

Desch, Matthias, Sigl, K., Hieke, Bernhard, Salb, Katharina, Kees, F. and Bernhard, D. (2010) IRAG determines nitric oxide- and atrial natriuretic peptide-mediated smooth muscle relaxation. Cardiovascular Research 86 (3), pp. 496-505. Fulltext not available.

Dorn, Christoph

, Riener, Marc-Oliver, Kirovski, Georgi, Saugspier, Michael, Steib, Kathrin, Weiss, Thomas S., Gäbele, Erwin, Kristiansen, Glen, Hartmann, Arndt and Hellerbrand, Claus (2010) Expression of fatty acid synthase in nonalcoholic fatty liver disease. International Journal of Clinical and Experimental Pathology 3 (5), pp. 505-514.

Schnell, David and Seifert, Roland (2010) Modulation of Histamine H(3) receptor function by monovalent ions. Neuroscience Letters 472 (2), pp. 114-118. Fulltext not available.

Schnell, David, Burleigh, Katrina, Seifert, Roland and Trick, Jonathan (2010) No evidence for functional selectivity of proxyfan at the human histamine H3 receptor coupled to defined Gi/Go protein heterotrimers. Journal of Pharmacology and Experimental Therapeutics . JPET 332 (3), pp. 996-1005. Fulltext not available.

Dietl, Katrin, Renner, Kathrin, Dettmer, Katja, Timischl, Birgit, Eberhart, Karin, Dorn, Christoph

, Hellerbrand, Claus, Kastenberger, Michael, Kunz-Schughart, Leoni A., Oefner, Peter J., Andreesen, Reinhard, Gottfried, Eva and Kreutz, Marina (2010) Lactic acid and acidification inhibit TNF secretion and glycolysis of human monocytes. Journal of immunology 184 (3), pp. 1200-1209. Fulltext not available.

Strasser, Andrea and Wittmann, Hans-Joachim (2010) 3D-QSAR CoMFA study to predict orientation of suprahistaprodifens and phenoprodifens in the binding-pocket of four histamine H1-receptor species. Molecular Informatics 29, pp. 333-341. Fulltext not available.

Schoenhammer, K., Boisclair, J., Schuetz, H., Petersen, H. and Göpferich, Achim (2010) Biocompatibility of an injectable in situ forming depot for peptide delivery. European Journal of Pharmaceutical Sciences 99 (10), pp. 4390-4399. Fulltext not available.

Brandl, Ferdinand, Hammer, Nadine, Blunk, Torsten, Teßmar, Jörg and Göpferich, Achim (2010) Biodegradable hydrogels for time-controlled release of tethered peptides or proteins. Biomacromolecules 11 (2), pp. 496-504. Fulltext not available.

Bauer-Kreisel, Petra, Göpferich, Achim and Blunk, Torsten (2010) Cell-delivery therapeutics for adipose tissue regeneration. Advanced Drug Delivery Reviews 62 (7-8), pp. 798-813. Fulltext not available.

Strasser, Andrea and Wittmann, Hans-Joachim (2010) Distinct interactions between the human adrenergic b2 receptor and Gas - an in silico study. J Mol Model 16, pp. 1307-1318. Fulltext not available.

Brandl, Ferdinand, Seitz, Anna Katharina, Teßmar, Jörg, Blunk, Torsten and Göpferich, Achim (2010) Enzymatically degradable poly(ethylene glycol) based hydrogels for adipose tissue engineering. Biomaterials 31 (14), pp. 3957-3966. Fulltext not available.

Brandl, Ferdinand, Kastner, Fritz, Gschwind, R. M., Blunk, Torsten, Teßmar, Jörg and Göpferich, Achim (2010) Hydrogel-based drug delivery systems: Comparison of drug diffusivity and release kinetics. Journal of Controlled Release 142 (2), pp. 221-228. Fulltext not available.

Berndl, Sina, Breunig, Miriam, Göpferich, Achim and Wagenknecht, Hans-Achim (2010) Imaging of RNA delivery to cells by thiazole orange as a fluorescent RNA base substitution. Organic & Biomolecular Chemistry 8 (5), pp. 997-999. Fulltext not available.

Schneider, Erich, Schnell, David, Strasser, Andrea, Dove, Stefan and Seifert, Roland (2010) Impact of the DRY motif and the missing "ionic lock" on constitutive activity and G-protein coupling of the human histamine H4 receptor. J Pharmacol Exp Ther : The journal of pharmacology and experimental therapeutics 333 (2), pp. 382-392. Fulltext not available.

Strasser, Andrea and Wittmann, Hans-Joachim (2010) In silico analysis of the histaprodifen induced pathway of the guinea-pig histamine H1 receptor. Journal of computer- aided molecular design : J Comput Aided Mol Des 24, pp. 759-769. Fulltext not available.

Henke, Matthias, Brandl, Ferdinand, Göpferich, Achim and Teßmar, Jörg (2010) Size-dependent release of fluorescent macromolecules and nanoparticles from radically cross-linked hydrogels. European Journal of Pharmaceutics and Biopharmaceutics 74 (2), pp. 184-192. Fulltext not available.

Holzhauser, C., Berndl, Sina, Menacher, Florian, Breunig, Miriam, Göpferich, Achim and Wagenknecht, Hans-Achim (2010) Synthesis and Optical Properties of Cyanine Dyes as Fluorescent DNA Base Substitutions for Live Cell Imaging. European Journal of Organic Chemistry (7), pp. 1239-1248. Fulltext not available.

Zaky, A., Elbakry, Asmaa, Ehmer, Axel, Breunig, Miriam and Göpferich, Achim (2010) The mechanism of protein release from triglyceride microspheres. Journal of Controlled Release 147 (2), pp. 202-210. Fulltext not available.

Dorn, Christoph

, Bataille, Frauke, Gaebele, Erwin, Heilmann, Jörg and Hellerbrand, Claus (2010) Xanthohumol feeding does not impair organ function and homoeostasis in mice. Food and Chemical Toxicology 48 (7), pp. 1890-1897. Fulltext not available.

Dorn, Christoph

, Kraus, Birgit, Motyl, Magdalena, Weiss, Thomas S., Gehrig, Manfred, Schoelmerich, Juergen, Heilmann, Jörg and Hellerbrand, Claus (2010) Xanthohumol, a chalcon derived from hops, inhibits hepatic inflammation and fibrosis. Molecular nutrition & food research 54 (Suppl.), S205-S213. Fulltext not available.

Dorn, Christoph

, Weiss, Thomas S., Heilmann, Jörg and Hellerbrand, Claus (2010) Xanthohumol, a prenylated chalcone derived from hops, inhibits proliferation, migration and interleukin-8 expression of hepatocellular carcinoma cells. International journal of oncology 36 (2), pp. 435-441. Fulltext not available.

Göpferich, Achim and Rothschenk, Stefan (2009) Cross-linked polymer matrix, in particular for administering protein drugs into the eye. DE102008016998. Fulltext not available.

Arndt, Stephanie, Mägdefrau, Ulrike, Dorn, Christoph

, Schardt, Katharina, Hellerbrand, Claus and Bosserhoff, Anja–Katrin (2009) Iron-Induced Expression of Bone Morphogenic Protein 6 in Intestinal Cells Is the Main Regulator of Hepatic Hepcidin Expression In Vivo. Gastroenterology 138 (1), pp. 372-382. Fulltext not available.

Schoenhammer, K., Petersen, H., Guethlein, F. and Göpferich, Achim (2009) Poly(ethylene-glycol) 500 Dimethylether as Novel Solvent for Injectable In Situ Forming Depots. Pharmaceutical Research 26 (12), pp. 2568-2577. Fulltext not available.

Weiser, Barbara, Sommer, Florian, Neubauer, M., Seitz, Anna Katharina, Teßmar, Jörg, Göpferich, Achim and Blunk, Torsten (2009) Ascorbic Acid Enhances Adipogenesis of Bone Marrow-Derived Mesenchymal Stromal Cells. Cells Tissues Organs 189 (6), pp. 373-381. Fulltext not available.

Wittmann, Hans-Joachim, Seifert, Roland and Strasser, Andrea (2009) Contribution of binding enthalpy and entropy to affinity of antagonist and agonist binding at human and guinea pig histamine H1-receptor. Molecular Pharmacology 76, pp. 25-37. Fulltext not available.

Bauhuber, Sonja, Hozsa, Constantin, Breunig, Miriam and Göpferich, Achim (2009) Delivery of Nucleic Acids via Disulfide-Based Carrier Systems. Advanced Materials (Weinheim, Germany) 21 (32-33), pp. 3286-3306. Fulltext not available.

Beule, A. G., Steinmeier, E., Kaftan, H., Biebler, K.-E., Göpferich, Achim, Wolf, Eva and Hosemann, W. (2009) Effects of a dexamethasone-releasing stent on osteoneogenesis in a rabbit model. American journal of rhinology & allergy 23 (4), pp. 433-436. Fulltext not available.

Schuessele, Andrea, Mayr, H., Teßmar, Jörg and Göpferich, Achim (2009) Enhanced BMP-2 performance on hydroxyapatite ceramic surfaces. Journal of Biomedical Materials Research Part A 90A (4), pp. 959-971. Fulltext not available.

Sommer, Florian, Brandl, Ferdinand, Weiser, Barbara, Teßmar, Jörg, Blunk, Torsten and Göpferich, Achim (2009) FACS as useful tool to study distinct hyalocyte populations. Experimental Eye Research 88 (5), pp. 995-999. Fulltext not available.

Schoenhammer, K., Petersen, H., Guethlein, F. and Göpferich, Achim (2009) Injectable in situ forming depot systems: PEG-DAE as novel solvent for improved PLGA storage stability. International Journal of Pharmaceutics 371 (1-2), pp. 33-39. Fulltext not available.

Deml, Karl-Friedrich, Beermann, S, Neumann, Detlef, Strasser, Andrea and Seifert, Roland (2009) Interactions of histamine H1-receptor agonists and antagonists with the human histamine H4-receptor. Mol Pharmacol : Molecular pharmacology 76 (5), pp. 1019-1030. Fulltext not available.

Elbakry, Asmaa, Zaky, A., Liebl, Renate, Rachel, Reinhard, Göpferich, Achim and Breunig, Miriam (2009) Layer-by-Layer Assembled Gold Nanoparticles for siRNA Delivery. Nano Letters 9 (5), pp. 2059-2064. Fulltext not available.

Wobser, Hella, Dorn, Christoph

, Weiss, Thomas S., Amann, Thomas, Bollheimer, Cornelius, Büttner, Roland, Schölmerich, Jürgen and Hellerbrand, Claus (2009) Lipid accumulation in hepatocytes induces fibrogenic activation of hepatic stellate cells. Cell Research 19 (8), pp. 996-1005. Fulltext not available.

Strasser, Andrea (2009) Molecular Modelling and QSAR-based design of histamine receptor ligands. Expert Opinion on Drug Discovery (4), pp. 1061-1075. Fulltext not available.

Appel, Bernhard, Baumer, Julia, Eyrich, Daniela, Sarhan, Hatem, Taso, S., Englert, Carsten and Göpferich, Achim (2009) Synergistic effects of growth and differentiation factor-5 (GDF-5) and insulin on expanded chondrocytes in a 3-D environment. Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 17 (11), pp. 1503-1512. Fulltext not available.

Koelwel, C., Rothschenk, Stefan, Fuchs-Koelwel, B., Gabler, B., Lohmann, C. and Göpferich, Achim (2008) Alginate inserts loaded with epidermal growth factor for the treatment of keratoconjunctivitis sicca. Pharmaceutical Development and Technology 13 (3), pp. 221-231. Fulltext not available.

Beule, A. G., Scharf, C., Biebler, K.-E., Göpferich, Achim, Steinmeier, E., Wolf, E., Hosemann, W. and Kaftan, H. (2008) Effects of Topically Applied Dexamethasone on Mucosal Wound Healing Using a Drug-Releasing Stent. The Laryngoscope 118 (11), pp. 2073-2077. Fulltext not available.

Sommer, Florian, Pollinger, Klaus, Brandl, Ferdinand, Weiser, Barbara, Teßmar, Jörg, Blunk, Torsten and Göpferich, Achim (2008) Hyalocyte proliferation and ECM accumulation modulated by bFGF and TGF-β1. Graefe's Archive for Clinical and Experimental Ophthalmology 246 (9), pp. 1275-1284. Fulltext not available.

Weiser, Barbara, Prantl, Lukas, Schubert, Thomas E. O., Zellner, J., Fischbach-Teschl, Claudia, Spruss, Thilo, Seitz, Anna Katharina, Teßmar, Jörg, Göpferich, Achim and Blunk, Torsten (2008) In Vivo Development and Long-Term Survival of Engineered Adipose Tissue Depend on In Vitro Precultivation Strategy. Tissue Engineering Part A 14 (2), pp. 275-284. Fulltext not available.

Göpferich, Achim (2008) Interactive polymers for pharmaceutical and biomedical applications. European journal of pharmaceutics and biopharmaceutics 68 (1), p. 1. Fulltext not available.

Breunig, Miriam, Hosza, C., Lungwitz, Uta, Watanabe, K., Umeda, I., Kato, H. and Göpferich, Achim (2008) Mechanistic investigation of poly(ethylene imine)-based siRNA delivery: Disulfide bonds boost intracellular release of the cargo. Journal of Controlled Release 130 (1), pp. 57-63. Fulltext not available.

Lungwitz, Uta, Breunig, Miriam, Liebl, Renate, Blunk, Torsten and Göpferich, Achim (2008) Methoxy poly(ethylene glycol) – Low molecular weight linear polyethylenimine-derived copolymers enable polyplex shielding. European Journal of Pharmaceutics and Biopharmaceutics 69 (1), pp. 134-148. Fulltext not available.

Gäbele, Erwin, Mühlbauer, Marcus, Dorn, Christoph

, Weiss, Thomas S., Froh, Matthias, Schnabl, Bernd, Wiest, Reiner, Schölmerich, Jürgen, Obermeier, Florian and Hellerbrand, Claus (2008) Role of TLR9 in hepatic stellate cells and experimental liver fibrosis. Biochemical and Biophysical Research Communications 376 (2), pp. 271-276. Fulltext not available.

Preuss, Hendrik, Ghorai, Prasanta, Kraus, Anja, Dove, Stefan, Buschauer, Armin and Seifert, Roland (2007) Point Mutations in the Second Extracellular Loop of the Histamine H2 Receptor do not affect the Species-Selective Activity of Guanidine-Type Agonists. Naunyn Schmiedebergs Arch. Pharmacol. 376 (4), pp. 253-264. Fulltext restricted.

Klinker, J. F., Schwaner, I., Offermanns, S., Hagelüken, A. and Seifert, Roland (1994) Differential activation of dibutyryl cAMP-differentiated HL-60 human leukemia cells by chemoattractants. Biochemical pharmacology 48 (10), pp. 1857-1864.

Wenzel-Seifert, K., Schächtele, C., Hummel, R., Grünbaum, L. and Seifert, Roland (1994) Evidence that inhibition of phorbol ester-induced superoxide anion formation by cyclosporin A in phagocytes is not mediated by direct inhibition of protein kinase C. Biochemical pharmacology 48 (5), pp. 859-864.

Seifert, Roland, Grünbaum, L. and Schultz, Günter (1994) Histamine H1-receptors in HL-60 monocytes are coupled to Gi-proteins and pertussis toxin-insensitive G-proteins and mediate activation of Ca2+ influx without concomitant Ca2+ mobilization from intracellular stores. Naunyn-Schmiedeberg's archives of pharmacology 349 (4), pp. 355-361.

Musgrave, I. F. and Seifert, Roland (1994) Human neutrophils and HL-60 cells do not possess alpha 2-adrenoceptors. Biochemical pharmacology 47 (2), pp. 233-239.

Hagelüken, A., Grünbaum, L., Nürnberg, B., Harhammer, R., Schunack, W. and Seifert, Roland (1994) Lipophilic beta-adrenoceptor antagonists and local anesthetics are effective direct activators of G-proteins. Biochemical pharmacology 47 (10), pp. 1789-1795.

Musgrave, I. F., Seifert, Roland and Schultz, Günter (1994) Maitotoxin activates cation channels distinct from the receptor-activated non-selective cation channels of HL-60 cells. The Biochemical journal 301 ( Pt 2, pp. 437-441.

Klinker, J. F., Hagelüken, A., Grünbaum, L., Heilmann, I., Nürnberg, B., Harhammer, R., Offermanns, S., Schwaner, I., Ervens, J., Wenzel-Seifert, K., Müller, T. and Seifert, Roland (1994) Mastoparan may activate GTP hydrolysis by Gi-proteins in HL-60 membranes indirectly through interaction with nucleoside diphosphate kinase. The Biochemical journal 304 ( Pt 2, pp. 377-383.

Wenzel-Seifert, K., Schächtele, C. and Seifert, Roland (1994) N-protein kinase C isoenzymes may be involved in the regulation of various neutrophil functions. Biochemical and biophysical research communications 200 (3), pp. 1536-1543.

Blunk, Torsten (1994) Plasmaproteinadsorption auf kolloidalen Arzneistoffträgern. Analytik, Korrelation mit Oberflächeneigenschaften, Implikationen für das Drug Targeting. PhD, Kiel, Univ..

Naim, M., Seifert, Roland, Nürnberg, B., Grünbaum, L. and Schultz, Günter (1994) Some taste substances are direct activators of G-proteins. The Biochemical journal 297 ( Pt 3, pp. 451-454.

Berger, M., Offermanns, S., Seifert, Roland and Schultz, Günter (1994) Synthetic lipopeptide Pam3CysSer(Lys)4 is an effective activator of human platelets. The American journal of physiology 266 (6 Pt 1), C1684-C1691.

Seifert, Roland, Hagelüken, A., Höer, A., Höer, D., Grünbaum, L., Offermanns, S., Schwaner, I., Zingel, V., Schunack, W. and Schultz, Günter (1994) The H1 receptor agonist 2-(3-chlorophenyl)histamine activates Gi proteins in HL-60 cells through a mechanism that is independent of known histamine receptor subtypes. Molecular Pharmacology 45 (4), pp. 578-586.

Tsang, K. W., Roberts, P., Read, R. C., Kees, Frieder, Wilson, R. and Cole, P. J. (1994) The concentrations of clarithromycin and its 14-hydroxy metabolite in sputum of patients with bronchiectasis following single dose oral administration. The Journal of antimicrobial chemotherapy 33 (2), pp. 289-297.

Honeybourne, D., Kees, Frieder K., Andrews, J. M., Baldwin, D. and Wise, R. (1994) The levels of clarithromycin and its 14-hydroxy metabolite in the lung. The European respiratory journal 7 (7), pp. 1275-1280.

Blunk, Torsten, Mak, E. and Müller, R. H. (1993) Characterization of Colloidal Drug Carriers. Die pharmazeutische Industrie : pharmind 55 (6), pp. 612-615.

Sedlmayr, T., Petersen, F., Raasch, W. and Kees, Frieder K. (1993) Clarithromycin, ein neues Makrolid-Antibiotikum. Wirksamkeit bei puerperalen Infektionen und Übertritt in die Muttermilch [Clarithromycin, a new macrolide antibiotic. Effectiveness in puerperal infections and pharmacokinetics in breast milk]. Geburtshilfe und Frauenheilkunde 53 (7), pp. 488-491.

Blunk, Torsten, Hochstrasser, D. F., Sanchez, J. C., Müller, B. W. and Müller, R. H. (1993) Colloidal carriers for intravenous drug targeting: plasma protein adsorption patterns on surface-modified latex particles evaluated by two-dimensional polyacrylamide gel electrophoresis. Electrophoresis 14 (12), pp. 1382-1387.

Wenzel-Seifert, Katharina and Seifert, Roland (1993) Cyclosporin H is a potent and selective formyl peptide receptor antagonist. Comparison with N-t-butoxycarbonyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L- leucyl-L-phenylalanine and cyclosporins A, B, C, D, and E. The Journal of Immunology 150 (10), pp. 4591-4599.

Bernhardt, Günther (1993) Entwicklung und Anwendung moderner Testverfahren zur Auffindung und Optimierung der Antitumorwirkung neuartiger Diphenylethylendiaminplatin(II)-Komplexe. Habilitation, Regensburg, Universität.

Klinker, J. F., Höer, A., Schwaner, I., Offermanns, S., Wenzel-Seifert, Katharina and Seifert, Roland (1993) Lipopeptides activate Gi-proteins in dibutyryl cyclic AMP-differentiated HL-60 cells. The Biochemical journaL 296 ( Pt 1, pp. 245-251.

Wenzel-Seifert, Katharina and Seifert, Roland (1993) Partial inhibition of human neutrophil activation by FK-506 at supratherapeutic concentrations. Naunyn-Schmiedeberg's archives of pharmacology 348 (1), pp. 7-13.

Grobecker, H. F. and Kees, Frieder K. (1993) Pharmacokinetic parameters and haemodynamic actions of midodrine in young volunteers. International angiology : a journal of the International Union of Angiology 12 (2), pp. 119-124.

Musgrave, I. F., Genieser, H. G., Maronde, E. and Seifert, Roland (1993) Preparations of Rp-cyclic adenosine 3',5'-phosphorothioate (Rp-cAMPS) can contain biologically active amounts of adenosine. FEBS letters 318 (3), pp. 227-230.

Rudt, S., Blunk, Torsten and Müller, R. H. (1992) Quantification of Cell Subpopulations, Fractions of Dead
Cells and Debris in Cell Suspensions by Laser Diffractometry. Die pharmazeutische Industrie 54 (11), pp. 966-969.

Müller, R. H., Lherm, C., Herbort, J., Blunk, Torsten and Couvreur, P. (1992) Alkylcyanoacrylate drug carriers: I. Physicochemical characterization of nanoparticles with different alkyl chain length. International Journal of Pharmaceutics 84 (1), pp. 1-11.

Dominiak, P., Kees, Frieder K., Welzel, D. and Grobecker, H. (1992) Cardiovascular parameters and catecholamines in volunteers during passive orthostasis. Influence of antihypotensive drugs. Arzneimittel-Forschung 42 (5), pp. 637-642.

Krautwurst, D., Seifert, Roland, Hescheler, J. and Schultz, Günter (1992) Formyl peptides and ATP stimulate Ca2+ and Na+ inward currents through non-selective cation channels via G-proteins in dibutyryl cyclic AMP-differentiated HL-60 cells. Involvement of Ca2+ and Na+ in the activation of beta-glucuronidase release and superoxide production. The Biochemical journal 288 ( Pt 3, pp. 1025-1035.

Klinz, F. J., Seifert, Roland, Schwaner, I., Gausepohl, H., Frank, R. and Schultz, Günter (1992) Generation of specific antibodies against the rap1A, rap1B and rap2 small GTP-binding proteins. Analysis of rap and ras proteins in membranes from mammalian cells. European journal of biochemistry 207 (1), pp. 207-213.

Seifert, Roland, Höer, Ariane, Offermann, Stefan, Buschauer, Armin and Schunack, Walter (1992) Histamine increases Ca^2+ in dibutyryl cyclic AMP-differentiated HL-60 cells via H_1-receptors and is an incomplete secretagogue. Mol. Pharmacol. 42, pp. 227-234.

Seifert, Roland, Höer, Ariane, Schwaner, Ingo and Buschauer, Armin (1992) Histamine increases cytosolic Ca^2+ in HL-60 promyelocytes predominantly via H_2-receptors with an unique agonist/antagonist profile and induces functional differentiation. Molecular Pharmacology 42, pp. 235-241.

Seifert, Roland, Serke, S., Huhn, D., Bessler, W. G., Hauschildt, S., Metzger, J., Wismüller, K. H. and Jung, G. (1992) Incomplete functional differentiation of HL-60 leukemic cells by synthetic lipopeptides. Partial inhibition by pertussis toxin of enhanced superoxide formation. European journal of biochemistry / FEBS 203 (1-2), pp. 143-151.

Offermanns, S., Seifert, Roland, Metzger, J. W., Jung, G., Lieberknecht, A., Schmidt, U. and Schultz, Günter (1992) Lipopeptides are effective stimulators of tyrosine phosphorylation in human myeloid cells. Biochemical Journal 282 ( Pt 2, pp. 551-7.

Ervens, J. and Seifert, Roland (1992) Molsidomine inhibits the chemoattractant-induced respiratory burst in human neutrophils via a no-independent mechanism. Biochemical pharmacology 44 (4), pp. 637-644.

Kees, Frieder K. (1992) Orale Cephalosporine [Oral cephalosporins]. Medizinische Monatsschrift für Pharmazeuten 15 (1), pp. 2-10.

Schwaner, I., Seifert, Roland and Schultz, Günter (1992) Receptor-mediated increases in cytosolic Ca2+ in the human erythroleukaemia cell line involve pertussis toxin-sensitive and -insensitive pathways. The Biochemical journal 281 ( Pt 2, pp. 301-307.

Kees, Frieder K., Raasch, W. and Grobecker, H. F. (1992) Strukturelle Charakterisierung eines unbekannten Metaboliten von Ciprofloxacin [Structural characterization of an unknown metabolite of ciprofloxacin]. Arzneimittel-Forschung 42 (4), pp. 570-575.

Schwaner, I., Seifert, Roland and Schultz, Günter (1992) The prostacyclin analogues, cicaprost and iloprost, increase cytosolic Ca2+ concentration in the human erythroleukemia cell line, HEL, via pertussis toxin-insensitive G-proteins. Eicosanoids 5 Suppl, S10-512. Fulltext not available.

Kees, Frieder K., Lukassek, U., Naber, K. G. and Grobecker, H. (1991) Comparative investigations on the bioavailability of cefuroxime axetil. Arzneimittel-Forschung 41 (8), pp. 843-846.

Bernhardt, Günther, Spruss, Thilo and Schönenberger, Helmut (1991) Einsatz menschlicher Tumorzellkulturen als Testmodelle bei der Entwicklung von Wirkstoffen für die Krebstherapie. Forum für interdisziplinäre Forschung : FIF 4, pp. 24-28.

Seifert, Roland and Schultz, Günter (1991) The superoxide- forming NADPH oxidase of phagocytes: an enzyme system regulated by multiple mechanisms. Reviews of physiology, biochemistry, and pharmacology, 117. Springer, Berlin. ISBN 3-540-53663-9, 0-387-53663-9.

Seifert, Roland, Schultz, Günter, Richter-Freund, M., Metzger, J., Wiesmüller, K. H., Jung, G., Bessler, W. G. and Hauschildt, S. (1990) Activation of superoxide formation and lysozyme release in human neutrophils by the synthetic lipopeptide Pam3Cys-Ser-(Lys)4. Involvement of guanine-nucleotide-binding proteins and synergism with chemotactic peptides. The Biochemical journal 267 (3), pp. 795-802.

Jungblut, P. R. and Seifert, Roland (1990) Analysis by high-resolution two-dimensional electrophoresis of differentiation-dependent alterations in cytosolic protein pattern of HL-60 leukemic cells. Journal of biochemical and biophysical methods 21 (1), pp. 47-58.

Burde, Rahel, Buschauer, Armin and Seifert, Roland (1990) Characterization of histamine H_2-receptors in human neutrophils with a series of guanidine analogues of impromidine: Are cell type-specific H_2-receptors involved in the regulation of NADPH oxidase? Naunyn-Schmiedeberg's Archives of Pharmacology 341, pp. 455-461.

Kees, Frieder K., Raasch, W., Steger, M. and Grobecker, H. (1990) High-performance liquid chromatographic assay for cefotiam and d3-cefotiam in human serum. Journal of Chromatography B 525 (2), pp. 484-489.

Wenzel-Seifert, Katharina and Seifert, Roland (1990) Nucleotide-, chemotactic peptide- and phorbol ester-induced exocytosis in HL-60 leukemic cells. Immunobiology 181 (4-5), pp. 298-316.

Kees, Frieder K. and Naber, K. G. (1990) Pharmakokinetik von Cefixim bei Probanden und ein Literaturvergleich mit neuen Ester Prodrug Cephalosporinen [Pharmacokinetics of cefixime in volunteers and a literature comparison with the new ester prodrug cephalosporins]. Infection 18 Suppl 3, S150-S154.

Kees, Frieder K., Naber, K. G., Sigl, G., Ungethüm, W. and Grobecker, H. F. (1990) Relative bioavailability of three cefixime formulations. Arzneimittel-Forschung 40 (3), pp. 293-297.

Korting, H. C., Schäfer-Korting, M., Kees, Frieder K., Lukacs, A. and Grobecker, H. (1990) Skin tissue fluid levels of cefotiam in healthy man following oral cefotiam hexetil. European journal of clinical pharmacology 39 (1), pp. 33-36.

Kees, Frieder K., Dehner, R., Dittrich, W., Raasch, W. and Grobecker, H. F. (1990) Untersuchungen zur Bioverfügbarkeit von Doxycy [The bioavailability of doxycycline]. Arzneimittel-Forschung 40 (9), pp. 1039-1043.

Seifert, Roland, Burde, R. and Schultz, Günter (1989) Activation of NADPH oxidase by purine and pyrimidine nucleotides involves G proteins and is potentiated by chemotactic peptides. The Biochemical journal 259 (3), pp. 813-819.

Engel, K. J., Schmidt, W., Sonntag, H. G. and Kees, Frieder K. (1989) Comparative clinical and pharmacokinetic aspects of cefotetan versus cefoxitin plus metronidazole in vaginal hysterectomy. Journal of chemotherapy 1 (4 Supl), pp. 1053-1056. Fulltext not available.

Seifert, Roland, Jungblut, P. and Schultz, Günter (1989) Differential expression of cytosolic activation factors for NADPH oxidase in HL-60 leukemic cells. Biochemical and biophysical research communications 161 (3), pp. 1109-1117.

Naber, K. G., Sörgel, F., Kees, Frieder K., Schumacher, H., Sigl, G., Zürcher, J. and Berger, S. (1989) Enoxacin-Konzentrationen in der Samenflüssigkeit, im Prostatasekret und im Prostataadenomgewebe nach oraler Gabe oder intravenöser Infusion [Enoxacin concentration in seminal fluid, in prostate secretions and in prostatic adenoma tissue following oral administration or intravenous infusion]. Infection 17 Suppl 1, S30-S66.

Schmidt, H. H., Seifert, Roland and Böhme, E. (1989) Formation and release of nitric oxide from human neutrophils and HL-60 cells induced by a chemotactic peptide, platelet activating factor and leukotriene B4. FEBS letters 244 (2), pp. 357-360.

Rudolph, U., Koesling, D., Hinsch, K. D., Seifert, Roland, Bigalke, M., Schultz, Günter and Rosenthal, W. (1989) G-protein alpha-subunits in cytosolic and membranous fractions of human neutrophils. Molecular and cellular endocrinology 63 (1-2), pp. 143-153.

Burde, Rahel, Seifert, Roland, Buschauer, Armin and Schultz, Günther (1989) Histamine inhibits activation of human neutrophils and HL-60 leukemic cells via H_2-receptors. Naunyn-Schmiedeberg's archives of pharmacology 340, pp. 671-678.

Seifert, Roland and Schultz, Günter (1989) Involvement of pyrimidinoceptors in the regulation of cell functions by uridine and by uracil nucleotides. Trends in pharmacological sciences 10 (9), pp. 365-369.

Seifert, Roland, Burde, R. and Schultz, Günter (1989) Lack of effect of opioid peptides, morphine and naloxone on superoxide formation in human neutrophils and HL-60 leukemic cells. Naunyn-Schmiedeberg's archives of pharmacology 340 (1), pp. 101-106.

Kees, Frieder K., Naber, K. G., Meyer, G. P. and Grobecker, H. (1989) Pharmacokinetics of ciprofloxacin in elderly patients. Arzneimittel-Forschung 39 (4), pp. 523-527.

Naber, K. G., Sörgel, F., Kees, Frieder K., Jaehde, U. and Schumacher, H. (1989) Pharmacokinetics of ciprofloxacin in young (healthy volunteers) and elderly patients, and concentrations in prostatic fluid, seminal fluid, and prostatic adenoma tissue following intravenous administration. The American journal of medicine 87 (5supl1), S57-S59.

Seifert, Roland, Wenzel, Katharina, Eckstein, F. and Schultz, Günter (1989) Purine and pyrimidine nucleotides potentiate activation of NADPH oxidase and degranulation by chemotactic peptides and induce aggregation of human neutrophils via G proteins. European journal of biochemistry / FEBS 181 (1), pp. 277-285.

Kujath, P., Düsel, W., Bruch, H. P. and Kees, Frieder K. (1989) The pharmacokinetic properties of cefotetan and its relevance for prophylaxis in elective colorectal surgery. Journal of chemotherapy 1 (4 Supl), pp. 1002-1004. Fulltext not available.

Seifert, Roland, Schächtele, C., Rosenthal, W. and Schultz, Günter (1988) Activation of protein kinase C by cis- and trans-fatty acids and its potentiation by diacylglycerol. Biochemical and biophysical research communications 154 (1), pp. 20-26.

Engel, K. J., Schmidt, W., Sonntag, H. G. and Kees, Frieder K. (1988) Comparative clinical and pharmacokinetic aspects of cefotetan versus cefoxitin plus metronidazole in vaginal hysterectomy. Chemioterapia 7 (4), pp. 256-260. Fulltext not available.

Naber, K. G., Sörgel, F., Kees, Frieder K., Schumacher, H., Metz, R. and Grobecker, H. (1988) In-vitro activity of fleroxacin against isolates causing complicated urinary tract infections and concentrations in seminal and prostatic fluid and in prostatic adenoma tissue. The Journal of antimicrobial chemotherapy 22 Suppl D, pp. 199-207.

Kees, Frieder K., Naber, K. G., Schumacher, H. and Grobecker, H. (1988) Penetration of fleroxacin into prostatic secretion and prostatic adenoma tissue. Chemotherapy 34 (6), pp. 437-443. Fulltext not available.

Schächtele, C., Seifert, Roland and Osswald, H. (1988) Stimulus-dependent inhibition of platelet aggregation by the protein kinase C inhibitors polymyxin B, H-7 and staurosporine. Biochemical and biophysical research communications 151 (1), pp. 542-547.

Seifert, Roland and Schächtele, C. (1988) Studies with protein kinase C inhibitors presently available cannot elucidate the role of protein kinase C in the activation of NADPH oxidase. Biochemical and biophysical research communications 152 (2), pp. 585-592.

Kujath, P., Düsel, W., Bruch, H. P. and Kees, Frieder K. (1988) The pharmacokinetic properties of cefotetan and its relevance for prophylaxis in elective colorectal surgery. Chemioterapia 7 (4), pp. 229-232. Fulltext not available.

Seifert, Roland, Rosenthal, W., Schultz, Günter, Wieland, T., Gierschick, P. and Jakobs, K. H. (1988) The role of nucleoside-diphosphate kinase reactions in G protein activation of NADPH oxidase by guanine and adenine nucleotides. European journal of biochemistry / FEBS 175 (1), pp. 51-55.

Seifert, Roland, Schächtele, C. and Schultz, Günter (1987) Activation of protein kinase C by cis- and trans-octadecadienoic acids in intact human platelets and its potentiation by diacylglycerol. Biochemical and biophysical research communications 149 (2), pp. 762-768.

Naber, K., Kees, Frieder K., Denk, K., Bauernfeind, A. and Grobecker, H. (1987) Carumonam versus ceftazidime: in vitro activity, pharmacokinetics in elderly patients, safety and therapeutic efficacy in the treatment of complicated urinary tract infections. Chemioterapia 6 (2 Supl), pp. 517-518. Fulltext not available.

Seifert, Roland and Schultz, Günter (1987) Fatty-acid-induced activation of NADPH oxidase in plasma membranes of human neutrophils depends on neutrophil cytosol and is potentiated by stable guanine nucleotides. European journal of biochemistry / FEBS 162 (3), pp. 563-569.

Naber, K. G., Adam, D. and Kees, Frieder K. (1987) In vitro activity and concentrations in serum, urine, prostatic secretion and adenoma tissue of ofloxacin in urological patients. Drugs 34 Suppl 1, S44-S50. Fulltext not available.

Seifert, Roland and Schultz, Günter (1987) Reversible activation of NADPH oxidase in membranes of HL-60 human leukemic cells. Biochemical and biophysical research communications 146 (3), pp. 1296-1302.

Kees, Frieder K., Dominiak, P. and Grobecker, H. (1987) Untersuchungen zur Bioverfügbarkeit von Heptaminol bei Probanden [Bioavailability of heptaminol in healthy subjects]. Arzneimittel-Forschung 37 (10), pp. 1182-1185.

Grobecker, H., Kees, Frieder K., Linden, M., Schrader, E. and Welte, S. (1987) Untersuchungen zur Bioverfügbarkeit von Midodrin und 2,5- Dimethoxyphenyl-ß-aminoethanol-hydrochlorid [The bioavailability of midodrin and alpha-2,5-dimethoxyphenyl-beta-aminoethanol hydrochloride]. Arzneimittel-Forschung 37 (4), pp. 447-450.

Dominiak, P., Kees, Frieder K. and Grobecker, H. (1986) Circulating and tissue catecholamines in rats with chronic neurogenic hypertension. Basic research in cardiology 81 (1), pp. 20-28.

Seifert, Roland, Rosenthal, W. and Schultz, Günter (1986) Guanine nucleotides stimulate NADPH oxidase in membranes of human neutrophils. FEBS letters 205 (1), pp. 161-165.

Bernhardt, Günther (1986) Hochdruckuntersuchungen an thermophilen Bakterien. PhD, Regensburg, Universität.

Martinez, C., Dominiak, P., Kees, Frieder K. and Grobecker, H. (1986) Inhibition of monoamine oxidase by viloxazine in rats. Arzneimittel-Forschung 36 (5), pp. 800-803.

Seifert, Roland (1986) Nikotinamidmethylierung in normalen Geweben und Tumorzellen von Ratte und Maus. PhD, Berlin, Freie Universität.

Naber, K. G., Dette, G. A., Kees, Frieder K., Knothe, H. and Grobecker, H. (1986) Pharmacokinetics, in-vitro activity, therapeutic efficacy and clinical safety of aztreonam vs. cefotaxime in the treatment of complicated urinary tract infections. The Journal of antimicrobial chemotherapy 17 (4), pp. 517-527.

Grobecker, H., Gessler, I., Delius, W., Dominiak, P. and Kees, Frieder K. (1985) Effect of ketanserin on hemodynamics, plasma-catecholamine concentrations, and serotonin uptake by platelets in volunteers and patients with congestive heart failure. Journal of cardiovascular pharmacology 7, Suppl 7, S102-S104.

Kees, Frieder K., Naber, K. G., Bartoschik-Wich, B., Stockmann, P., Meyer, G. P. and Grobecker, H. (1985) High-performance liquid chromatography analysis of mezlocillin, piperacillin, their degradation products, and of ioxitalamic acid in plasma and urine of healthy volunteers. Arzneimittel-Forschung 35 (7), pp. 1099-1104.

Dominiak, P., Kees, Frieder K. and Grobecker, H. (1985) Sympathoadrenal dysfunction in rats with chronic neurogenic hypertension. European journal of pharmacology 107 (2), pp. 263-266.

Dominiak, P., Kees, Frieder K. and Grobecker, H. (1984) Changes in peripheral and central catecholaminergic and serotoninergic neurons of rats after acute and subacute administration of nicotine. Klinische Wochenschrift. Supplementum 62 Suppl 2, pp. 76-80. Fulltext not available.

Kees, Frieder K., Grobecker, H. and Naber, K. G. (1984) High-performance liquid chromatographic analysis of cefotetan epimers in human plasma and urine. Journal of Chromatography B 305 (2), pp. 363-371.

Schleicher, E. D., Kees, Frieder K. and Wieland, O. H. (1983) Analysis of total urinary catecholamines by liquid chromatography: methodology, routine experience and clinical interpretations of results. Clinica chimica acta 129 (3), pp. 295-302.

Kees, Frieder K., Strehl, E., Dominiak, P., Grobecker, H., Seeger, K., Seidel, G., Neuhaus, B. and Safrany, L. (1983) Cefotaxime and desacetyl cefotaxime in human bile. Infection 11 (2), pp. 118-120.

Naber, K. G., Kees, Frieder K. and Grobecker, H. (1983) Ceftazidime: pharmacokinetics in young volunteers versus elderly patients and therapeutic efficacy with complicated urinary tract infections. The Journal of antimicrobial chemotherapy 12 Suppl A, pp. 41-45.

Kees, Frieder K., Strehl, E., Seeger, K., Seidel, G., Dominiak, P. and Grobecker, H. (1981) Comparative determination of cefotaxime and desacetyl cefotaxime in serum and bile by bioassay and high-performance liquid chromatography. Arzneimittel-Forschung 31 (2), pp. 362-365.

Kees, Frieder K. (1976) Thiaziridindioxide, Thiadiaziridindioxide und ein Beitrag zur Staudinger-Pfenninger-Reaktion. PhD, Univ. Würzburg. Fulltext not available.

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