Anzahl der Einträge in dieser Kategorie: 654.
Unterholzner, Anna,
Kuck, Katrin,
Weinzierl, Anna,
Lipowicz, Bartosz und
Heilmann, Jörg
(2024)
An Unprecedented 4,8-Cycloeudesmane, Further New Sesquiterpenoids, a Triterpene, Steroids, and a Lignan from the Resin of Commiphora myrrha and Their Anti-Inflammatory Activity In Vitro.
Molecules 29 (18), S. 4315.
Schorr, Kathrin,
Chen, Xinyu,
Sasaki, Takanori,
Arias-Loza, Anahi Paula,
Lang, Johannes,
Higuchi, Takahiro und
Goepferich, Achim
(2024)
Rethinking Thin-Layer Chromatography for Screening Technetium-99m Radiolabeled Polymer Nanoparticles.
ACS Pharmacology & Translational Science 7 (9), S. 2604-2611.
Schatz, Lea Marie,
Greppmair, Sebastian,
Kunzelmann, Alexandra K.,
Starp, Johannes,
Brinkmann, Alexander,
Roehr, Anka,
Frey, Otto,
Hagel, Stefan,
Dorn, Christoph ,
Zoller, Michael,
Scharf, Christina,
Wicha, Sebastian G. und
Liebchen, Uwe
(2024)
Predictive performance of multi-model approaches for model-informed precision dosing of piperacillin in critically ill patients.
International Journal of Antimicrobial Agents 64 (4), S. 107305.
Brummer, Christina,
Singer, Katrin,
Brand, Almut,
Bruss, Christina,
Renner, Kathrin,
Herr, Wolfgang,
Pukrop, Tobias,
Dorn, Christoph ,
Hellerbrand, Claus,
Matos, Carina und
Kreutz, Marina
(2024)
Sex-Dependent T Cell Dysregulation in Mice with Diet-Induced Obesity.
International Journal of Molecular Sciences 25 (15), S. 8234.
Lier, Constantin,
Dejaco, Alexander ,
Kratzer, Alexander,
Kees, Martin G. ,
Kees, Frieder und
Dorn, Christoph
(2024)
Free serum concentrations of antibiotics determined by ultrafiltration: extensive evaluation of experimental variables.
Bioanalysis, S. 1-10.
Volltext nicht vorhanden.
Scheuerer, Simon,
Motlova, Lucia,
Schäker-Hübner, Linda,
Sellmer, Andreas,
Feller, Felix,
Ertl, Fabian J.,
Koch, Pierre ,
Hansen, Finn K.,
Barinka, Cyril und
Mahboobi, Siavosh
(2024)
Biological and structural investigation of tetrahydro-β-carboline-based selective HDAC6 inhibitors with improved stability.
European Journal of Medicinal Chemistry 276, S. 116676.
Mietzner, Raphael ,
Barbey, Clara,
Lehr, Heike,
Ziegler, Christian E.,
Peterhoff, David ,
Wagner, Ralf ,
Goepferich, Achim und
Breunig, Miriam
(2024)
Prolonged delivery of HIV-1 vaccine nanoparticles from hydrogels.
International Journal of Pharmaceutics 657, S. 124131.
Hosmann, Arthur,
Moser, Miriam M,
van Os, Wisse,
Gramms, Leon,
al Jalali, Valentin,
Sanz Codina, Maria,
Plöchl, Walter,
Lier, Constantin,
Kees, Frieder ,
Dorn, Christoph ,
Rössler, Karl,
Reinprecht, Andrea und
Zeitlinger, Markus
(2024)
Linezolid brain penetration in neurointensive care patients.
Journal of Antimicrobial Chemotherapy, dkae025.
Dejaco, Alexander ,
Dorn, Christoph ,
Paal, Michael,
Gruber, Michael ,
Graf, Bernhard M. und
Kees, Martin G.
(2024)
Determination of glomerular filtration rate “en passant” after high doses of iohexol for computed tomography in intensive care medicine—a proof of concept.
Frontiers in Pharmacology 15.
Haase, André,
Miroschnikov, Natalia,
Klein, Stefan,
Doege, Annika,
Dünker, Nicole,
Van Meenen, Dario,
Junker, Andreas,
Göpferich, Achim ,
Apaolaza, P. S. und
Busch, Maike Anna
(2024)
New retinoblastoma (RB) drug delivery approaches: anti-tumor effect of atrial natriuretic peptide (ANP)-conjugated hyaluronic-acid-coated gold nanoparticles for intraocular treatment of chemoresistant RB.
Molecular Oncology 18 (4), S. 832-849.
Volltext nicht vorhanden.
Wulkersdorfer, Beatrix,
Bergmann, Felix,
Amann, Lisa,
Fochtmann-Frana, Alexandra,
Al Jalali, Valentin,
Kurdina, Elizaveta,
Lackner, Edith,
Wicha, Sebastian G,
Dorn, Christoph ,
Schäfer, Bruno,
Ihra, Gerald,
Rath, Thomas,
Radtke, Christine und
Zeitlinger, Markus
(2023)
Effect of albumin substitution on pharmacokinetics of piperacillin/tazobactam in patients with severe burn injury admitted to the ICU.
Journal of Antimicrobial Chemotherapy.
Nagl, Martin,
Moennich, Denise,
Rosier, Niklas ,
Schihada, Hannes,
Sirbu, Alexei,
Konar, Nergis,
Reyes-Resina, Irene,
Navarro, Gemma,
Franco, Rafael,
Kolb, Peter,
Annibale, Paolo und
Pockes, Steffen
(2023)
Fluorescent Tools for the Imaging of Dopamine D2‐Like Receptors.
ChemBioChem.
Rosier, Niklas ,
Moennich, Denise,
Nagl, Martin,
Schihada, Hannes,
Sirbu, Alexei,
Konar, Nergis,
Reyes-Resina, Irene,
Navarro, Gemma,
Franco, Rafael,
Kolb, Peter,
Annibale, Paolo und
Pockes, Steffen
(2023)
Shedding Light on the D1‐Like Receptors: A Fluorescence‐Based Toolbox for Visualization of the D1 and D5 Receptors.
ChemBioChem.
Greppmair, Sebastian,
Brinkmann, Alexander,
Roehr, Anka,
Frey, Otto,
Hagel, Stefan,
Dorn, Christoph ,
Marsot, Amélie,
El-Haffaf, Ibrahim,
Zoller, Michael,
Saller, Thomas,
Zander, Johannes,
Schatz, Lea Marie,
Scharf, Christina,
Briegel, Josef,
Minichmayr, Iris K.,
Wicha, Sebastian G. und
Liebchen, Uwe
(2023)
Towards model-informed precision dosing of piperacillin: multicenter systematic external evaluation of pharmacokinetic models in critically ill adults with a focus on Bayesian forecasting.
Intensive Care Medicine.
Chen, Zhendong,
Taubert, Max,
Chen, Chunli,
Dokos, Charalambos,
Fuhr, Uwe,
Weig, Thomas,
Zoller, Michael,
Heck, Suzette,
Dimitriadis, Konstantinos,
Terpolilli, Nicole,
Kinast, Christina,
Scharf, Christina,
Lier, Constantin,
Dorn, Christoph und
Liebchen, Uwe
(2023)
Plasma and Cerebrospinal Fluid Population Pharmacokinetics of Vancomycin in Patients with External Ventricular Drain.
Antimicrobial Agents and Chemotherapy.
Volltext nicht vorhanden.
Wirth, Ulrike,
Erl, Julia,
Azzam, Saphia,
Hoering, Carina,
Skiba, Michael,
Singh, Ritu,
Hochmuth, Kathrin,
Keller, Max ,
Wegener, Joachim und
König, Burkhard
(2023)
Monitoring the Reversibility of GPCR Signaling by Combining Photochromic Ligands with Label-free Impedance Analysis.
Angewandte Chemie International Edition, e202215547.
Sanz-Codina, Maria,
Wicha, Sebastian G,
Wulkersdorfer, Beatrix,
Al Jalali, Valentin,
Van Os, Wisse,
Vossen, Matthias G,
Bauer, Martin,
Lackner, Edith,
Dorn, Christoph und
Zeitlinger, Markus
(2022)
Comparison of ultrafiltration and microdialysis for ceftriaxone protein-binding determination.
Journal of Antimicrobial Chemotherapy.
Volltext nicht vorhanden.
Jorda, Anselm ,
Wulkersdorfer, Beatrix,
Schoergenhofer, Christian,
Matzneller, Peter,
Jalali, Valentin A. L.,
Bauer, Martin,
Wölfl‐Duchek, Michael,
Lackner, Edith,
Dorn, Christoph ,
Jilma, Bernd und
Zeitlinger, Markus
(2022)
Effect of the human endotoxin challenge on tedizolid tissue penetration.
British Journal of Clinical Pharmacology, (accept.art.).
Volltext nicht vorhanden.
Schindler, Lisa,
Moosbauer, Jutta,
Schmidt, Daniel ,
Spruss, Thilo,
Grätz, Lukas,
Lüdeke, Steffen,
Hofheinz, Frank,
Meister, Sebastian,
Echtenacher, Bernd,
Bernhardt, Günther,
Pietzsch, Jens ,
Hellwig, Dirk und
Keller, Max
(2022)
Development of a Neurotensin-Derived 68Ga-Labeled PET Ligand with High In Vivo Stability for Imaging of NTS1 Receptor-Expressing Tumors.
Cancers 14 (19), S. 4922.
Bohley, Marilena,
Dillinger, Andrea E.,
Schweda, Frank,
Ohlmann, Andreas,
Braunger, Barbara M.,
Tamm, Ernst R. und
Goepferich, Achim
(2022)
A single intravenous injection of cyclosporin A–loaded lipid nanocapsules prevents retinopathy of prematurity.
Science Advances 8 (38).
Heinl, Elena-Sofia,
Lorenz, Sebastian,
Schmidt, Barbara ,
Laqtom, Nouf Nasser M.,
Mazzulli, Joseph R.,
Francelle, Laetitia ,
Yu, Timothy W.,
Greenberg, Benjamin ,
Storch, Stephan,
Tegtmeier, Ines,
Othmen, Helga,
Maurer, Katja,
Steinfurth, Malin,
Witzgall, Ralph,
Milenkovic, Vladimir M.,
Wetzel, Christian H. und
Reichold, Markus
(2022)
CLN7/MFSD8 may be an important factor for SARS-CoV-2 cell entry.
iScience 25 (10), S. 105082.
Dorn, Christoph ,
Petroff, David,
Kratzer, Alexander,
Kees, Frieder,
Kloft, Charlotte,
Zeitlinger, Markus ,
Wrigge, Hermann und
Simon, Philipp
(2022)
Tigecycline Soft Tissue Penetration in Obese and Non-obese Surgical Patients Determined by Using In Vivo Microdialysis.
European Journal of Drug Metabolism and Pharmacokinetics 47, S. 749-755.
Meurer, Florian ,
Dolomanov, Oleg V.,
Hennig, Christoph ,
Peyerimhoff, Norbert ,
Kleemiss, Florian ,
Puschmann, Horst und
Bodensteiner, Michael
(2022)
Refinement of anomalous dispersion correction parameters in single-crystal structure determinations.
IUCrJ / International Union of Crystallography 9 (5), S. 604-609.
Willkomm, Sarah ,
Jakob, Leonhard,
Kramm, Kevin,
Graus, Veronika,
Neumeier, Julia,
Meister, Gunter und
Grohmann, Dina
(2022)
Single-molecule FRET uncovers hidden conformations and dynamics of human Argonaute 2.
Nature Communications 13, art.no.3825.
Bresinsky, Merlin,
Strasser, Jessica M.,
Hubmann, Alexander,
Vallaster, Bernadette,
McCue, William M.,
Fuller, Jessica,
Singh, Gurpreet,
Nelson, Kathryn M.,
Cuellar, Matthew E.,
Finzel, Barry C.,
Ashe, Karen H.,
Walters, Michael A. und
Pockes, Steffen
(2022)
Characterization of caspase‐2 inhibitors based on specific sites of caspase‐2‐mediated proteolysis.
Archiv der Pharmazie 355 (9), S. 2200095.
Jorda, Anselm ,
Wulkersdorfer, Beatrix,
Schörgenhofer, Christian,
Matzneller, Peter ,
Al Jalali, Valentin,
Bauer, Martin ,
Wölf-Duchek, Michael,
Lackner, Edith,
Dorn, Christoph,
Jilma, Bernd und
Zeitlinger, Markus
(2022)
Influence of tedizolid on the cytokine response to the endotoxin challenge in healthy volunteers: a cross-over trial.
Journal of Antimicrobial Chemotherapy.
Volltext nicht vorhanden.
Ousingsawat, Jiraporn ,
Centeio, Raquel,
Cabrita, Inês ,
Talbi, Khaoula,
Zimmer, Oliver ,
Graf, Moritz,
Göpferich, Achim ,
Schreiber, Rainer und
Kunzelmann, Karl
(2022)
Airway Delivery of Hydrogel-Encapsulated Niclosamide for the Treatment of Inflammatory Airway Disease.
International Journal of Molecular Sciences 23 (3), S. 1085.
Rösch, Gundula,
Muschter, Dominique,
Taheri, Shahed ,
El Bagdadi, Karima,
Dorn, Christoph,
Meurer, Andrea,
Zaucke, Frank,
Schilling, Arndt F.,
Grässel, Susanne,
Straub, Rainer H. und
Jenei-Lanzl, Zsuzsa
(2022)
β2-Adrenoceptor Deficiency Results in Increased Calcified Cartilage Thickness and Subchondral Bone Remodeling in Murine Experimental Osteoarthritis.
Frontiers in Immunology 12.
Tahk, Maris-Johanna ,
Torp, Jane ,
Ali, Mohammed A. S. ,
Fishman, Dmytro,
Parts, Leopold ,
Grätz, Lukas ,
Müller, Christoph ,
Keller, Max ,
Veiksina, Santa ,
Laasfeld, Tõnis und
Rinken, Ago
(2022)
Live-cell microscopy or fluorescence anisotropy with budded baculoviruses—which way to go with measuring ligand binding to M 4 muscarinic receptors?
Open Biology 12 (6).
Volltext nicht vorhanden.
Barda, Christina,
Anastasiou, Konstantina,
Tzara, Ariadni,
Grafakou, Maria-Eleni,
Kalpoutzakis, Eleftherios,
Heilmann, Joerg,
Rallis, Michael,
Kourounakis, Angeliki P. und
Skaltsa, Helen
(2022)
A Bio-Guided Screening for Antioxidant, Anti-Inflammatory and Hypolipidemic Potential Supported by Non-Targeted Metabolomic Analysis of Crepis spp.
Molecules 27 (19), S. 6173.
Volltext nicht vorhanden.
Andreev, Stanislav,
Pantsar, Tatu,
Tesch, Roberta,
Kahlke, Niclas,
El-Gokha, Ahmed,
Ansideri, Francesco,
Grätz, Lukas,
Romasco, Jenny,
Sita, Giulia,
Geibel, Christian ,
Lämmerhofer, Michael,
Tarozzi, Andrea,
Knapp, Stefan ,
Laufer, Stefan A. und
Koch, Pierre
(2022)
Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors.
Journal of Medicinal Chemistry 65 (2), S. 1283-1301.
Volltext nicht vorhanden.
Mandigma, Mark John P. ,
Žurauskas, Jonas,
MacGregor, Callum I.,
Edwards, Lee J. ,
Shahin, Ahmed ,
d'Heureuse, Ludwig,
Yip, Philip,
Birch, David J. S. ,
Gruber, Thomas,
Heilmann, Jörg,
John, Matthew P. und
Barham, Joshua P.
(2022)
An organophotocatalytic late-stage N–CH3oxidation of trialkylamines toN-formamides with O2in continuous flow.
Chemical Science 13 (7), S. 1912-1924.
Volltext nicht vorhanden.
Katsouri, Ilektra Petrina,
Vandervelpen, Ebert Vinciane G.,
Gattor, Albert Owusu,
Engelbeen, Sarah,
El Sayed, Abdulrahman,
Seitaj, Klejdia,
Becerra, Eduardo Daniel Morales und
Vanderheyden, Patrick M.L.
(2022)
Complex FFA1 receptor (in)dependent modulation of calcium signaling by free fatty acids.
Biochemical Pharmacology 202, S. 115150.
Volltext nicht vorhanden.
Schoretsanitis, Georgios,
Haen, Ekkehard,
Piacentino, Daria,
Conca, Andreas,
Endres, Katharina,
Hiemke, Christoph,
Gründer, Gerhard und
Paulzen, Michael
(2022)
Effects of body weight, smoking status, and sex on plasma concentrations of once-monthly paliperidone palmitate.
Expert Review of Clinical Pharmacology 15 (2), S. 243-249.
Volltext nicht vorhanden.
Beyer, Mandy,
Henninger, Sven J.,
Haehnel, Patricia S.,
Mustafa, Al-Hassan M. ,
Gurdal, Ece ,
Schubert, Bastian,
Christmann, Markus,
Sellmer, Andreas ,
Mahboobi, Siavosh,
Drube, Sebastian,
Sippl, Wolfgang,
Kindler, Thomas und
Krämer, Oliver H.
(2022)
Identification of a highly efficient dual type I/II FMS-like tyrosine kinase inhibitor that disrupts the growth of leukemic cells.
Cell Chemical Biology 29 (3), 398-411.e4.
Volltext nicht vorhanden.
Schihada, Hannes,
Klompstra, Thomas M. ,
Humphrys, Laura J. ,
Cervenka, Igor,
Dadvar, Shamim ,
Kolb, Peter ,
Ruas, Jorge L. und
Schulte, Gunnar
(2022)
Isoforms of GPR35 have distinct extracellular N-termini that allosterically modify receptor-transducer coupling and mediate intracellular pathway bias.
Journal of Biological Chemistry 298 (9), S. 102328.
Volltext nicht vorhanden.
Peterhoff, David ,
Thalhauser, Stefanie,
Neckermann, Patrick ,
Barbey, Clara,
Straub, Kristina,
Nazet, Julian,
Merkl, Rainer,
Längst, Gernot,
Breunig, Miriam und
Wagner, Ralf
(2022)
Multivalent display of engineered HIV-1 envelope trimers on silica nanoparticles for targeting and in vitro activation of germline VRC01 B cells.
European Journal of Pharmaceutics and Biopharmaceutics 181, S. 88-101.
Volltext nicht vorhanden.
Schindler, Lisa,
Wohlfahrt, Katrin,
Gluhacevic von Krüchten, Lara,
Prante, Olaf,
Keller, Max und
Maschauer, Simone
(2022)
Neurotensin analogs by fluoroglycosylation at Nω-carbamoylated arginines for PET imaging of NTS1-positive tumors.
Scientific Reports 12 (1).
Volltext nicht vorhanden.
Greinwald, Anja,
Hartmann, Martin,
Heilmann, Jörg,
Heinrich, Michael,
Luick, Rainer und
Reif, Albert
(2022)
Soil and Vegetation Drive Sesquiterpene Lactone Content and Profile in Arnica montana L. Flower Heads From Apuseni-Mountains, Romania.
Frontiers in Plant Science 13.
Volltext nicht vorhanden.
Szczepańska, Katarzyna,
Podlewska, Sabina,
Dichiara, Maria,
Gentile, Davide,
Patamia, Vincenzo,
Rosier, Niklas,
Mönnich, Denise,
Ruiz Cantero, Ma Carmen,
Karcz, Tadeusz,
Łażewska, Dorota,
Siwek, Agata,
Pockes, Steffen,
Cobos, Enrique J.,
Marrazzo, Agostino,
Stark, Holger,
Rescifina, Antonio,
Bojarski, Andrzej J.,
Amata, Emanuele und
Kieć-Kononowicz, Katarzyna
(2022)
Structural and Molecular Insight into Piperazine and Piperidine Derivatives as Histamine H3 and Sigma-1 Receptor Antagonists with Promising Antinociceptive Properties.
ACS Chemical Neuroscience 13 (1), S. 1-15.
Volltext nicht vorhanden.
Müller, Christoph,
Gleixner, Jakob ,
Tahk, Maris-Johanna ,
Kopanchuk, Sergei ,
Laasfeld, Tõnis,
Weinhart, Michael,
Schollmeyer, Dieter,
Betschart, Martin U.,
Lüdeke, Steffen,
Koch, Pierre,
Rinken, Ago und
Keller, Max
(2022)
Structure-Based Design of High-Affinity Fluorescent Probes for the Neuropeptide Y Y1 Receptor.
Journal of Medicinal Chemistry 65 (6), S. 4832-4853.
Volltext nicht vorhanden.
Rösch, G.,
El Bagdadi, K.,
Muschter, D.,
Taheri, S. ,
Dorn, C.,
Meurer, A.,
Straub, R.H.,
Zaucke, F. ,
Schilling, A.F.,
Grässel, S. und
Jenei-Lanzl, Z.
(2022)
Sympathectomy aggravates subchondral bone changes during osteoarthritis progression in mice without affecting cartilage degeneration or synovial inflammation.
Osteoarthritis and Cartilage 30 (3), S. 461-474.
Volltext nicht vorhanden.
Mietzner, Raphael ,
Pawlak, Ramona ,
Tamm, Ernst R.,
Goepferich, Achim ,
Fuchshofer, Rudolf und
Breunig, Miriam
(2021)
Angiopoietin-1 Mimetic Nanoparticles for Restoring the Function of Endothelial Cells as Potential Therapeutic for Glaucoma.
Pharmaceuticals 15 (1), S. 18.
Busse, David,
Simon, Philipp,
Schmitt, Lisa,
Petroff, David,
Dorn, Christoph ,
Dietrich, Arne,
Zeitlinger, Markus,
Huisinga, Wilhelm,
Michelet, Robin,
Wrigge, Hermann und
Kloft, Charlotte
(2021)
Comparative Plasma and Interstitial Tissue Fluid Pharmacokinetics of Meropenem Demonstrate the Need for Increasing Dose and Infusion Duration in Obese and Non-obese Patients.
Clinical Pharmacokinetics.
Dorn, Christoph
(2021)
3.3. Informationen über Arzneimittel.
In:
Sax, Michael, (ed.)
Pharmazie für die Praxis : Lehrbuch für Pharmazeuten im Praktikum : Handbuch für die Apotheke.
Deutscher Apotheker Verlag, Stuttgart, S. 152-173.
ISBN 978-3-7692-7010-5.
Volltext nicht vorhanden.
Rösch, Gundula,
El Bagdadi, Karima,
Muschter, Dominique ,
Taheri, Shahed,
Dorn, Christoph ,
Meurer, Andrea,
Straub, Rainer H. ,
Zaucke, Frank ,
Schilling, Arndt F.,
Grässel, Susanne und
Jenei-Lanzl, Zsuzsa
(2021)
Sympathectomy aggravates subchondral bone changes during osteoarthritis progression in mice without affecting cartilage degeneration or synovial inflammation.
Osteoarthritis and Cartilage 30 (3), S. 461-474.
Volltext nicht vorhanden.
Wachholz, Vanessa,
Mustafa, Al-Hassan M.,
Zeyn, Yanira,
Henninger, Sven J.,
Beyer, Mandy,
Dzulko, Melanie,
Piée-Staffa, Andrea,
Brachetti, Christina,
Haehnel, Patricia S.,
Sellmer, Andreas,
Mahboobi, Siavosh,
Kindler, Thomas,
Brenner, Walburgis,
Nikolova, Teodora und
Krämer, Oliver H.
(2021)
Inhibitors of class I HDACs and of FLT3 combine synergistically against leukemia cells with mutant FLT3.
Archives of Toxicology 96 (1), S. 177-193.
Busse, David,
Borghardt, Jens Markus,
Petroff, David,
Pevzner, Alice,
Dorn, Christoph ,
El‐Najjar, Nahed,
Huisinga, Wilhelm,
Wrigge, Hermann,
Simon, Philipp und
Kloft, Charlotte
(2021)
EVALUATING PREDICTION METHODS FOR GLOMERULAR FILTRATION TO OPTIMISE DRUG DOSES IN OBESE AND NON‐OBESE PATIENTS.
British Journal of Clinical Pharmacology.
Volltext nicht vorhanden.
Höring, Carina ,
Conrad, Marcus,
Söldner, Christian A. ,
Wang, Jinan ,
Sticht, Heinrich ,
Strasser, Andrea und
Miao, Yinglong
(2021)
Specific Engineered G Protein Coupling to Histamine Receptors Revealed from Cellular Assay Experiments and Accelerated Molecular Dynamics Simulations.
International Journal of Molecular Sciences 22 (18), S. 1-21.
Busse, David ,
Simon, Philipp ,
Petroff, David,
Dorn, Christoph,
Schmitt, Lisa,
Bindellini, Davide,
Kratzer, Alexander,
Dietrich, Arne,
Zeitlinger, Markus,
Huisinga, Wilhelm ,
Michelet, Robin ,
Wrigge, Hermann und
Kloft, Charlotte
(2021)
Similar Piperacillin/Tazobactam Target Attainment in Obese versus Nonobese Patients despite Differences in Interstitial Tissue Fluid Pharmacokinetics.
Pharmaceutics 13 (9), S. 1380.
Breunig, Miriam,
Sonntag, Tobias,
Froemel, Franziska,
Stamer, W. Daniel,
Ohlmann, Andreas und
Fuchshofer, Rudolf
(2021)
Distribution of Gold Nanoparticles in the Anterior Chamber of the Eye after Intracameral Injection for Glaucoma Therapy.
Pharmaceutics 2021 (13), S. 901.
(Eingereicht)
Peterhoff, David ,
Thalhauser, Stefanie,
Sobczak, Jan M.,
Mohsen, Mona O.,
Voigt, Christoph,
Seifert, Nicole ,
Neckermann, Patrick,
Hauser, Alexandra ,
Ding, Song,
Sattentau, Quentin,
Bachmann, Martin F. ,
Breunig, Miriam und
Wagner, Ralf
(2021)
Augmenting the Immune Response against a Stabilized HIV-1 Clade C Envelope Trimer by Silica Nanoparticle Delivery.
Vaccines 9 (642), S. 1-24.
Schießer, Selina,
Hitzenbichler, Florian,
Kees, Martin Georg,
Kratzer, Alexander,
Lubnow, Matthias ,
Salzberger, Bernd ,
Kees, Frieder und
Dorn, Christoph
(2021)
Measurement of Free Plasma Concentrations of Beta-Lactam Antibiotics.
Therapeutic Drug Monitoring 43 (2), S. 264-270.
Volltext nicht vorhanden.
Hoffmeister, Helen,
Fuchs, Andreas ,
Komives, Elizabeth,
Groebner‐Ferreira, Regina,
Strobl, Laura,
Nazet, Julian,
Heizinger, Leonhard,
Merkl, Rainer,
Dove, Stefan und
Längst, Gernot
(2021)
Sequence and functional differences in the ATPase domains of CHD3 and SNF2H promise potential for selective regulability and drugability.
The FEBS Journal 288, S. 4000-4023.
Rosier, Niklas,
Grätz, Lukas,
Schihada, Hannes ,
Möller, Jan,
Işbilir, Ali ,
Humphrys, Laura J. ,
Nagl, Martin,
Seibel, Ulla,
Lohse, Martin J. und
Pockes, Steffen
(2021)
A Versatile Sub-Nanomolar Fluorescent Ligand Enables NanoBRET Binding Studies and Single-Molecule Microscopy at the Histamine H3 Receptor.
Journal of Medicinal Chemistry 64 (15), S. 11695-11708.
Volltext nicht vorhanden.
Tropmann, Katharina,
Bresinsky, Merlin,
Forster, Lisa,
Mönnich, Denise,
Buschauer, Armin ,
Wittmann, Hans-Joachim,
Hübner, Harald,
Gmeiner, Peter,
Pockes, Steffen und
Strasser, Andrea
(2021)
Abolishing Dopamine D2long/D3 Receptor Affinity of Subtype-Selective Carbamoylguanidine-Type Histamine H2 Receptor Agonists.
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Controlling the Covalent Reactivity of a Kinase Inhibitor with Light.
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CNTF Attenuates Vasoproliferative Changes Through Upregulation of SOCS3 in a Mouse-Model of Oxygen-Induced Retinopathy.
Investigative Opthalmology & Visual Science 57 (10), S. 4017.
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Sawatzky, Edgar,
Wehle, Sarah,
Kling, Beata,
Wendrich, Jan,
Bringmann, Gerhard,
Sotriffer, Christoph A.,
Heilmann, Jörg und
Decker, Michael
(2016)
Discovery of Highly Selective and Nanomolar Carbamate-Based Butyrylcholinesterase Inhibitors by Rational Investigation into Their Inhibition Mode.
Journal of Medicinal Chemistry 59 (5), S. 2067-2082.
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Kariminia, Amina,
Holtan, Shernan G.,
Ivison, Sabine,
Rozmus, Jacob,
Hebert, Marie-Josée,
Martin, Paul J.,
Lee, Stephanie J.,
Wolff, Daniel,
Subrt, Peter,
Abdossamadi, Sayeh,
Sung, Susanna,
Storek, Jan,
Levings, Megan,
Aljurf, Mahmoud,
Arora, Mukta,
Cutler, Corey,
Gallagher, Geneviève,
Kuruvilla, John,
Lipton, Jeff,
Nevill, Thomas J.,
Newell, Laura F.,
Panzarella, Tony,
Pidala, Joseph,
Popradi, Gizelle,
Szwajcer, David,
Tay, Jason ,
Toze, Cynthia L.,
Walker, Irwin,
Couban, Stephen,
Storer, Barry E. und
Schultz, Kirk R.
(2016)
Heterogeneity of chronic graft-versus-host disease biomarkers: association with CXCL10 and CXCR3+ NK cells.
Blood 127 (24), S. 3082-3091.
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Dove, Stefan
(2016)
Mammalian Nucleotidyl Cyclases and Their Nucleotide Binding Sites.
In:
Seifert, Roland, (ed.)
Non-canonical Cyclic Nucleotides.
Handbook of Experimental Pharmacology, 238.
Springer International Publishing, Cham, Switzerland, S. 49-66.
ISBN 978-3-319-52673-7 (online), 978-3-319-52671-3 (print).
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Keller, Max,
Kuhn, Kilian K.,
Einsiedel, Jürgen,
Hübner, Harald,
Biselli, Sabrina,
Mollereau, Catherine ,
Wifling, David,
Svobodova, Jaroslava,
Bernhardt, Günther,
Cabrele, Chiara ,
Vanderheyden, Patrick,
Gmeiner, Peter und
Buschauer, Armin
(2016)
Mimicking of arginine by functionalized Nω-carbamoylated arginine as a new broadly applicable approach to labeled bioactive peptides: high affinity angiotensin, neuropeptide Y, neuropeptide FF and neurotensin receptor ligands as examples.
Journal of Medicinal Chemistry 59 (5), S. 1925-1945.
Volltext nicht vorhanden.
Khan, Nadia,
Saad, Ali,
Nurulain, Syed M.,
Darras, Fouad H.,
Decker, Michael und
Sadek, Bassem
(2016)
The dual-acting H3 receptor antagonist and AChE inhibitor UW-MD-71 dose-dependently enhances memory retrieval and reverses dizocilpine-induced memory impairment in rats.
Behavioural Brain Research 297, S. 155-164.
Volltext nicht vorhanden.
Huang, Guozheng ,
Schramm, Simon,
Heilmann, Jörg,
Biedermann, David,
Křen, Vladimír und
Decker, Michael
(2016)
Unconventional application of the Mitsunobu reaction: Selective flavonolignan dehydration yielding hydnocarpins.
Beilstein Journal of Organic Chemistry 12, S. 662-669.
Volltext nicht vorhanden.
Werner, Kristin,
Kälble, Solveig,
Wolter, Sabine,
Schneider, Erich H.,
Buschauer, Armin,
Neumann, Detlef und
Seifert, Roland
(2015)
Flow cytometric analysis with a fluorescent formyl peptide receptor ligand as a new method to study the pharmacological profile of the histamine H2-receptor.
Naunyn Schmiedebergs Archives of Pharmacology 388 (10), S. 1039-1052.
Volltext nicht vorhanden.
Wolferstetter, Stefanie,
Reinders, Jörg,
Schwede, Frank,
Ruth, Peter,
Schinner, Elisabeth und
Schlossmann, Jens
(2015)
Interaction of cCMP with the cGK, cAK and MAPK Kinases in Murine Tissues.
PLoS ONE 10 (5), e0126057.
Baumeister, Paul,
Erdmann, Daniela,
Biselli, Sabrina,
Kagermeier, Nicole,
Elz, Sigurd,
Bernhardt, Günther und
Buschauer, Armin
(2015)
3HUR-DE257: Development of a tritium-labeled squaramide-type selective histamine H2 receptor antagonist.
ChemMedChem 10 (1), S. 83-93.
Volltext nicht vorhanden.
Dolles, Dominik,
Nimczick, Martin,
Scheiner, Matthias,
Ramler, Jacqueline,
Stadtmüller, Patricia,
Sawatzky, Edgar,
Drakopoulos, Antonios ,
Sotriffer, Christoph,
Wittmann, Hans-Joachim,
Strasser, Andrea und
Decker, Michael
(2015)
Aminobenzimidazoles and Structural Isomers as Templates for Dual-Acting Butyrylcholinesterase Inhibitors andhCB2R Ligands To Combat Neurodegenerative Disorders.
ChemMedChem 11 (12), S. 1270-1283.
Volltext nicht vorhanden.
Orlando, Zoya,
Lengers, Isabelle,
Melzig, Matthias F.,
Buschauer, Armin,
Hensel, Andreas und
Jose, Joachim
(2015)
Autodisplay of human hyaluronidase Hyal-1 on Escherichia coli and identification of plant-derived enzyme inhibitors.
Molecules 20 (9), S. 15449-15468.
Kirchhof, Susanne,
Gregoritza, Manuel,
Messmann, Viktoria,
Hammer, Nadine,
Göpferich, Achim und
Brandl, Ferdinand
(2015)
Diels-Alder hydrogels with enhanced stability: First step toward controlled release of bevacizumab.
European Journal of Pharmaceutics and Biopharmaceutics 96, S. 217-225.
Volltext nicht vorhanden.
Kirchhof, Susanne,
Abrami, Michela,
Messmann, Viktoria,
Hammer, Nadine,
Goepferich, Achim,
Grassi, Mario und
Brandl, Ferdinand
(2015)
Diels–Alder hydrogels for controlled antibody release: Correlation between mesh size and release rate.
Molecular Pharmaceutics 12 (9), S. 3358-3368.
Volltext nicht vorhanden.
Lübker, Carolin,
Dove, Stefan,
Tang, Wei-Jen,
Bieber Urbauer, Ramona J.,
Moskovitz, Jackob,
Urbauer, Jeffrey L. und
Seifert, Roland
(2015)
Different Roles of N-Terminal and C-Terminal Domains in Calmodulin for Activation of Bacillus anthracis Edema Factor.
Toxins 7 (7), S. 2598-2614.
Kagermeier, Nicole,
Werner, Kristin,
Keller, Max,
Baumeister, Paul,
Bernhardt, Günther,
Seifert, Roland und
Buschauer, Armin
(2015)
Dimeric carbamoylguanidine-type histamine H2 receptor ligands: A new class of potent and selective agonists.
Bioorganic & Medicinal Chemistry 23 (14), S. 3957-3969.
Volltext nicht vorhanden.
Arndt, Stephanie,
Wacker, Eva,
Dorn, Christoph ,
Koch, Andreas,
Saugspier, Michael,
Thasler, W. E.,
Hartmann, Arndt,
Bosserhoff, Anja-Katrin und
Hellerbrand, Claus
(2015)
Enhanced expression of BMP6 inhibits hepatic fibrosis in non-alcoholic fatty liver disease.
Gut 64 (6), S. 973-981.
Huber, Stefan,
Huettner, Johannes Philip,
Hacker, Kristina,
Bernhardt, Günther,
König, Jörg und
Buschauer, Armin
(2015)
Esters of bendamustine are by far more potent cytotoxic agents than the parent compound against human sarcoma and carcinoma cells.
PLoS One 10 (7), PLoSe0133743.
Strasser, Andrea und
Buschauer, Armin
(2015)
Histaminrezeptoren.
Pharmakon 3 (2), S. 109-116.
Volltext nicht vorhanden.
Kirchhof, Susanne,
Goepferich, Achim und
Brandl, Ferdinand
(2015)
Hydrogels in ophthalmic applications.
European Journal of Pharmaceutics and Biopharmaceutics 95, part B, S. 227-238.
Volltext nicht vorhanden.
Keller, Max,
Tränkle, Christian,
She, Xueke,
Pegoli, Andrea,
Bernhardt, Günther,
Buschauer, Armin und
Read, Roger W.
(2015)
M2 subtype preferring dibenzodiazepinone-type muscarinic receptor ligands: effect of chemical homo-dimerization on orthosteric (and allosteric?) binding.
Bioorganic & Medicinal Chemistry 23 (14), S. 3970-3990.
Volltext nicht vorhanden.
Lübker, Carolin,
Bieber-Urbauer, Ramona J.,
Moskovitz, Jackob,
Dove, Stefan,
Weisemann, Jasmin,
Fedorova, Maria,
Urbauer, Jeffrey L. und
Seifert, Roland
(2015)
Membranous adenylyl cyclase 1 activation is regulated by oxidation of N- and C-terminal methionine residues in calmodulin.
Biochemical Pharmacology 93 (2), S. 196-209.
Volltext nicht vorhanden.
Wifling, David,
Löffel, Karolin,
Nordemann, Uwe,
Strasser, Andrea,
Bernhardt, Günther,
Dove, Stefan,
Seifert, Roland und
Buschauer, Armin
(2015)
Molecular determinants for the high constitutive activity of the human histamine H4 receptor: Functional studies on orthologs and mutants.
British Journal of Pharmacology 172, S. 785-798.
Volltext nicht vorhanden.
Kaczor, Agnieszka,
Guixa-Gonzalez, Ramon,
Carrio, Pau,
Poso, Antti,
Dove, Stefan,
Pastor, Manuel und
Selent, Jana
(2015)
Multi-Component Protein - Protein Docking Based Protocol with External Scoring for Modeling Dimers of G Protein-Coupled Receptors.
Molecular Informatics 34 (4), S. 246-255.
Volltext nicht vorhanden.
Hennig, Robert,
Ohlmann, Andreas,
Staffel, Janina,
Pollinger, Klaus,
Haunberger, Alexandra,
Breunig, Miriam,
Schweda, Frank,
Tamm, Ernst R. und
Goepferich, Achim
(2015)
Multivalent nanoparticles bind the retinal and choroidal vasculature.
Journal of Controlled Release 220 (Part A), S. 265-274.
Volltext nicht vorhanden.
Keller, Max,
Weiss, Stefan,
Hutzler, Christoph,
Kuhn, Kilian K.,
Mollereau, Catherine,
Dukorn, Stefanie,
Schindler, Lisa,
Bernhardt, Günther,
König, Burkhard und
Buschauer, Armin
(2015)
N(omega)-carbamoylation of the argininamide moiety: an avenue to insurmountable NPY Y1 receptor antagonists and a radiolabeled selective high affinity molecular tool ([3H]UR-MK299) with extended residence time.
Journal of Medicinal Chemistry 58 (22), S. 8834-8849.
Volltext nicht vorhanden.
Kirchhof, Susanne,
Strasser, Andrea,
Wittmann, Hans-Joachim,
Messmann, Viktoria,
Hammer, Nadine,
Goepferich, Achim und
Brandl, Ferdinand
(2015)
New insights into the cross-linking and degradation mechanism of Diels–Alder hydrogels.
Journal of Materials Chemistry B 3, S. 449-457.
Huber, Stefan,
Antoni, Frauke,
Schickaneder, Christian,
Schickaneder, Helmut,
Bernhardt, Günther und
Buschauer, Armin
(2015)
Stabilities of neutral and basic esters of bendamustine in plasma compared to the parent compound: Kinetic investigations by HPLC.
Journal of Pharmaceutical and Biomedical Analysis 104, S. 137-143.
Volltext nicht vorhanden.
Reinartz, Michael T.,
Kälble, Solveig,
Littmann, Timo,
Ozawa, Takeaki,
Dove, Stefan,
Kaever, Volkhard,
Wainer, Irving W. und
Seifert, Roland
(2015)
Structure-bias relationships for fenoterol stereoisomers in six molecular and cellular assays at the β2-adrenoceptor.
Naunyn-Schmiedeberg's archives of pharmacology 388 (1), S. 51-65.
Volltext nicht vorhanden.
Untergehrer, Monika,
Bücherl, Daniel,
Wittmann, Hans-Joachim,
Strasser, Andrea,
Heilmann, Jörg und
Jürgenliemk, Guido
(2015)
Structure-dependent deconjugation of flavonoid glucuronides by human beta-glucuronidase - in vitro and in silico analyses.
Planta Med. 81 (12/13), S. 1182-1189.
Volltext nicht vorhanden.
Herrnberger, Leonie,
Hennig, Robert,
Kremer, Werner,
Hellerbrand, Claus,
Goepferich, Achim,
Kalbitzer, Hans Robert und
Tamm, Ernst R.
(2014)
Formation of Fenestrae in Murine Liver Sinusoids Depends on Plasmalemma Vesicle-Associated Protein and Is Required for Lipoprotein Passage.
PLoS ONE 9 (12), e115005.
Cuboni, Serena,
Devigny, Christian,
Hoogeland, Bastiaan,
Strasser, Andrea,
Pomplun, Sebastian,
Hauger, Barbara,
Höfner, Georg,
Wanner, Klaus,
Eder, Matthias,
Buschauer, Armin,
Holsboer, Florian und
Hausch, Felix
(2014)
Loratadine and analogs: Discovery and preliminary SAR of inhibitors of the amino acid transporter B0AT2.
Journal of Medicinal Chemistry 57 (22), S. 9473-9479.
Volltext nicht vorhanden.
Slenczka, Alkwin,
Premke, Tobias,
Wirths, Eva-Maria,
Pentlehner, Dominik,
Lehnig, Rudolf,
Richers, Ricarda und
Vdovin, Alexander
(2014)
Microsolvation of Molecules in Superfluid Helium Nanodroplets Revealed by Means of Electronic Spectroscopy.
Frontiers in Chemistry.
Darras, Fouad,
Pockes, Steffen ,
Huang, Guozheng,
Wehle, Sarah,
Strasser, Andrea,
Wittmann, Hans-Joachim,
Nimczick, Martin,
Sotriffer, Christoph und
Decker, Michael
(2014)
Synthesis, biological evaluation, and computational studies of tri- and tetracyclic nitrogen-bridgehead compounds as potent dual-acting AChE inhibitors and hH3 receptor antagonists.
ACS Chemical Neuroscience 5 (3), S. 225-242.
Volltext nicht vorhanden.
Pollinger, Klaus,
Hennig, Robert,
Bauer, Stefanie,
Breunig, Miriam,
Tessmar, Joerg,
Buschauer, Armin,
Witzgall, Ralph und
Göpferich, Achim
(2014)
Biodistribution of quantum dots in the kidney after intravenous injection.
Journal of Nanoscience and Nanotechnology 14 (5), S. 3313-3319.
Volltext nicht vorhanden.
Pannem, Rajeswara Rao,
Dorn, Christoph ,
Ahlqvist, Kristofer,
Bosserhoff, Anja K.,
Hellerbrand, Claus und
Massoumi, Ramin
(2014)
CYLD controls c-MYC expression through the JNK-dependent signaling pathway in hepatocellular carcinoma.
Carcinogenesis 35 (2), S. 461-468.
Dorn, Christoph ,
Engelmann, Julia C.,
Saugspier, Michael,
Koch, Andreas,
Hartmann, Arndt,
Müller, Martina,
Spang, Rainer,
Bosserhoff, Anja und
Hellerbrand, Claus
(2014)
Increased expression of c-Jun in nonalcoholic fatty liver disease.
Laboratory Investigation 94 (4), S. 394-408.
Volltext nicht vorhanden.
Luschmann, Christoph,
Tessmar, Joerg,
Schoeberl, Simon,
Strauss, O.,
Luschmann, Karl und
Goepferich, Achim
(2014)
Self-assembling colloidal system for the ocular administration of cyclosporine A.
Cornea 33 (1), S. 77-81.
Volltext nicht vorhanden.
Geyer, Roland,
Igel, Patrick,
Kaske, Melanie,
Elz, Sigurd und
Buschauer, Armin
(2014)
Synthesis, SAR and selectivity of 2-acyl- and 2-cyano-1-hetarylalkyl-guanidines at the four histamine receptor subtypes: a bioisosteric approach.
MedChemComm 5 (1), S. 72-81.
Volltext nicht vorhanden.
Endlich, Nicole,
Simon, Ole,
Goepferich, Achim,
Wegner, Henny,
Moeller, Marcus J.,
Rumpel, Elisabeth,
Kotb, Ahmed und
Endlich, Karlhans
(2014)
Two-Photon Microscopy Reveals Stationary Podocytes in Living Zebrafish Larvae.
Journal of the American Society of Nephrology 25 (4), S. 681-686.
Volltext nicht vorhanden.
Schickaneder, Helmut,
Buschauer, Armin,
Bernhardt, Günther,
Schickaneder, Christian,
Limmert, Michael,
Huber, Stefan,
Lubbe, Mathias und
Hofmeier, Harald
(2013)
Esters of bendamustine and related compounds, and medical use thereof.
Volltext nicht vorhanden.
Schreeb, Annemarie,
Łażewska, Dorota,
Dove, Stefan,
Buschauer, Armin,
Kieć-Kononiwcz, Katarzyna und
Stark, Holger
(2013)
2. Histamine H4 receptor ligands.
In:
Stark, Holger, (ed.)
Histamine H4 receptor: a novel drug target for immunoregulation and inflammation.
Versita, London, S. 21-62.
ISBN 9788376560564.
Volltext nicht vorhanden.
Berlicki, Lukasz,
Kaske, Melanie,
Gutierrez-Abad, Raquel,
Bernhardt, Günther,
Illa, Ona,
Ortuño, Rosa,
Cabrele, Chiara,
Buschauer, Armin und
Reiser, Oliver
(2013)
Replacement of Thr32 and Gln34 in the C-terminal neuropeptide Y fragment 25-36 by cis-cyclobutane- and cis-cyclopentane β-amino acids shifts selectivity toward the Y4 receptor.
Journal of Medicinal Chemistry 56 (21), S. 8422-8431.
Volltext nicht vorhanden.
Nordemann, Uwe,
Wifling, David,
Schnell, David,
Bernhardt, Günther,
Stark, Holger,
Seifert, Roland und
Buschauer, Armin
(2013)
Luciferase reporter gene assay on human, murine and rat histamine H4 receptor orthologs: correlations and discrepancies between distal and proximal readouts.
PLoS One 8 (9), e73961.
Bauer, Stefanie,
Ochoa Puentes, Cristian,
Sun, Qiu,
Bause, Manuel,
Bernhardt, Günther,
König, Burkhard und
Buschauer, Armin
(2013)
Quinoline carboxamide-type ABCG2 modulators: Indole and quinoline moieties as anilide replacements.
ChemMedChem 8 (11), S. 1773-1778.
Volltext nicht vorhanden.
Brunskole Hummel, Irena,
Kälble, Solveig,
Burhenne, Heike,
Reinartz, Michael T.,
Schwede, Frank,
Buschauer, Armin und
Seifert, Roland
(2013)
Dissociations in the effects of beta2-adrenergic receptor agonists on cAMP formation and superoxide production in human neutrophils: Support for the concept of functional selectivity.
PLoS One 8 (5), e64556.
Zölls, Sarah,
Gregoritza, Manuel,
Tantipolphan, Ruedeeporn,
Wiggenhorn, Michael,
Winter, Gerhard,
Friess, Wolfgang und
Hawe, Andrea
(2013)
How Subvisible Particles Become Invisible - Relevance of the Refractive Index for Protein Particle Analysis.
Journal of Pharmaceutical Sciences 102 (5), S. 1434-1446.
Volltext nicht vorhanden.
Kees, Martin Georg,
Schaeftlein, André,
Haeberle, Helene Anna,
Kees, Frieder K.,
Kloft, Charlotte und
Heininger, Alexandra
(2013)
Population pharmacokinetics and pharmacodynamic evaluation of intravenous and enteral moxifloxacin in surgical intensive care unit patients.
The Journal of antimicrobial chemotherapy.
Volltext nicht vorhanden.
Ochoa-Puentes, Cristian,
Bauer, Stefanie,
Kühnle, Matthias,
Bernhardt, Günther,
Buschauer, Armin und
König, Burkhard
(2013)
Benzanilide – Biphenyl Replacement: A Bioisosteric Approach to Quinoline Carboxamide-type ABCG2 Modulators.
ACS Medicinal Chemistry Letters 4 (4), S. 393-396.
Volltext nicht vorhanden.
Seifert, Roland,
Strasser, Andrea,
Schneider, Erich H.,
Neumann, Detlef,
Dove, Stefan und
Buschauer, Armin
(2013)
Molecular and cellular analysis of human histamine receptor subtypes.
Trends in Pharmacological Sciences 34 (1), S. 33-58.
Volltext nicht vorhanden.
Krautbauer, Sabrina,
Wanninger, Josef,
Eisinger, Kristina,
Hader, Yvonne,
Beck, Michael,
Kopp, Andrea,
Schmid, Andreas,
Weiss, Thomas S. ,
Dorn, Christoph und
Buechler, Christa
(2013)
Chemerin is highly expressed in hepatocytes and is induced in non-alcoholic steatohepatitis liver.
Experimental and Molecular Pathology 95 (2), S. 199-205.
Volltext nicht vorhanden.
Luschmann, Christoph,
Tessmar, Joerg,
Schoeberl, Simon,
Framme, Carsten,
Luschmann, Karl und
Goepferich, Achim
(2013)
Developing an in situ nanosuspension: A novel approach towards the efficient administration of poorly soluble drugs at the anterior eye.
European Journal of Pharmaceutical Sciences 50 (3-4), S. 385-392.
Volltext nicht vorhanden.
Miller, Tobias,
van Colen, G.,
Sander, B.,
Golas, M.,
Uezguen, Senta,
Weigandt, Markus und
Goepferich, Achim
(2013)
Drug Loading of Polymerics Micelles.
Pharmaceutical Research 30 (2), S. 484-595.
Volltext nicht vorhanden.
Dietrich, P.,
Moleda, Lukas,
Kees, Frieder K.,
Müller, M.,
Straub, R. H.,
Hellerbrand, C. und
Wiest, R.
(2013)
Dysbalance in sympathetic neurotransmitter release and action in cirrhotic rats: impact of exogenous neuropeptide Y.
Journal of hepatology 58 (2), S. 254-261.
Volltext nicht vorhanden.
Ferstl, Matthias,
Drechsler, Markus,
Rachel, Reinhard,
Rischer, M.,
Engel, J.,
Backofen, Michael und
Goepferich, Achim
(2013)
Impact of Polyelectrolyte Structure on the Shape of Nanoassemblies with Cationic Peptides.
European Journal of Pharmaceutical Sciences 102, S. 2599-2607.
Volltext nicht vorhanden.
Mueller, M.,
Blunk, Torsten,
Appel, Bernhard,
Maschke, Angelika,
Goepferich, Achim und
Zellner, J.
(2013)
Insulin is essential for in vitro chondrogenesis of mesenchymal progenitor cells and influences chondrogenesis in a dose-dependent manner.
International orthopaedics 37 (1), S. 153-158.
Volltext nicht vorhanden.
Wurster, Eva-Christina,
Elbakry, Asmaa,
Goepferich, Achim und
Breunig, Miriam
(2013)
Layer-by-layer assembled gold nanoparticles for the delivery of nucleic acids.
In:
Nanotechnology for Nucleic Acid Delivery : Methods and Protocols.
Methods in Molecular Biology, 948.
Humana Press; Springer, Totowa, NJ, S. 171-182.
ISBN 978-1-62703-139-4 (print), 978-1-627-03140-0 (online).
Volltext nicht vorhanden.
Pollinger, Klaus,
Hennig, Robert,
Ohlmann, Andreas,
Fuchshofer, R.,
Wenzel, Rebecca und
Breunig, Miriam
(2013)
Ligand-functionalized nanoparticles target endothelial cells in retinal capillaries after systemic application.
Proceedings of the National Academy of Sciences of the United States of America (PNAS) 25, S. 6115-6120.
Volltext nicht vorhanden.
Schweizer, Daniel,
Vostiar, Igor,
Heier, Annabelle,
Serno, Tim,
Schoenhammer, Karin,
Jahn, Michael,
Jones, Stewart,
Piequet, Aline,
Beerli, Christian,
Gram, Hermann und
Goepferich, Achim
(2013)
Pharmacokinetics, biocompatibility and bioavailability of a controlled release monoclonal antibody formulation.
Journal of Controlled Release 172 (3), S. 975-982.
Volltext nicht vorhanden.
Miller, Tobias,
Breyer, S.,
van Colen, G.,
Mier, W.,
Haberkorn, U.,
Geissler, S.,
Voss, S.,
Weigandt, Markus und
Goepferich, Achim
(2013)
Premature drug release of polymeric micelles and its effects on tumor targeting.
International Journal of Pharmaceutics 445 (1-2), S. 117-124.
Volltext nicht vorhanden.
Göpferich, Achim
(2013)
To pause a moment.
European Journal of Pharmaceutics and Biopharmaceutics 85 (3), S. 328.
Volltext nicht vorhanden.
Memminger, Martin,
Keller, Max,
Lopuch, Miroslaw,
Pop, Nathalie,
Bernhardt, Günther,
von Angerer, Erwin und
Buschauer, Armin
(2012)
The Neuropeptide Y Y1 receptor: a diagnostic marker? Expression in MCF-7 breast cancer cells is down-regulated by antiestrogens in vitro and in xenografts.
PLoS ONE 7 (12), e51032.
Löber, Stefan,
Hübner, Harald,
Buschauer, Armin,
Sanna, Fabrizio,
Argiolas, Antonio,
Melis, Maria Rosaria und
Gmeiner, Peter
(2012)
Novel azulene derivatives for the treatment of erectile dysfunction.
Bioorganic & medicinal chemistry letters 22 (23), S. 7151-7154.
Volltext nicht vorhanden.
Birnkammer, Tobias,
Spickenreither, Anja,
Brunskole, Irena,
Lopuch, Miroslaw,
Kagermeier, Nicole,
Bernhardt, Günther,
Dove, Stefan,
Seifert, Roland,
Elz, Sigurd und
Buschauer, Armin
(2012)
The bivalent ligand approach leads to highly potent and selective acylguanidine-type histamine H2 receptor agonists.
Journal of Medicinal Chemistry 55 (3), S. 1147-1160.
Volltext nicht vorhanden.
Bauhuber, Sonja,
Liebl, Renate,
Tomasetti, Luise,
Rachel, Reinhard,
Goepferich, Achim und
Breunig, Miriam
(2012)
A library of strictly linear poly(ethylene glycol)-poly(ethylene imine) diblock coploymers to perform structure-function relationship on non-viral gene carriers.
Journal of Controlled Release 162, S. 446-455.
Volltext nicht vorhanden.
Miller, Tobias,
Rachel, Reinhard,
Besheer, Ahmed,
Uezguen, Senta,
Weigand, Markus und
Göpferich, Achim
(2012)
Comparative Investigations on In Vitro Serum Stability of Polymeric Micelle Formulations.
Pharmaceutical Research 29 (2), S. 448-459.
Volltext nicht vorhanden.
Posavec, Damir,
Zabel, Manfred,
Bogner, Udo,
Bernhardt, Günther und
Knör, Günther
(2012)
Functionalized derivatives of 1,4-dimethylnaphthalene as precursors for biomedical applications: synthesis, structures, spectroscopy and photochemical activation in the presence of dioxygen.
Organic & biomolecular chemistry 10 (35), S. 7062-7069.
Saugspier, Michael,
Dorn, Christoph ,
Thasler, Wolfgang E.,
Gehrig, Manfred,
Heilmann, Jörg und
Hellerbrand, Claus
(2012)
Hop bitter acids exhibit anti-fibrogenic effects on hepatic stellate cells in vitro.
Experimental and Molecular Pathology 92 (2), S. 222-228.
Volltext nicht vorhanden.
Saugspier, Michael,
Dorn, Christoph ,
Czech, Barbara,
Gehrig, Manfred,
Heilmann, Jörg und
Hellerbrand, Claus
(2012)
Hop bitter acids inhibit tumorigenicity of hepatocellular carcinoma cells in vitro.
Oncology Reports 28 (4), S. 1423-1428.
Volltext nicht vorhanden.
Appl, Heidrun,
Holzammer, Tobias,
Dove, Stefan,
Haen, Ekkehard,
Strasser, Andrea und
Seifert, Roland
(2012)
Interactions of recombinant human histamine H₁R, H₂R, H₃R, and H₄R receptors with 34 antidepressants and antipsychotics.
Naunyn-Schmiedeberg's archives of pharmacology 385 (2), S. 145-170.
Volltext nicht vorhanden.
Pollinger, Klaus,
Hennig, Robert,
Breunig, Miriam,
Teßmar, Jörg,
Ohlmann, Andreas,
Tamm, Ernst R.,
Witzgall, Ralph und
Goepferich, Achim
(2012)
Kidney Podocytes as Specific Targets for cyclo(RGDfC)-Modified Nanoparticles.
Small 8, S. 3368-3375.
Volltext nicht vorhanden.
Elbakry, Asmaa Mohamed,
Wurster, Eva-Christina,
Zaky, Alaa,
Liebl, Renate,
Schindler, Edith,
Bauer-Kreisel, Petra,
Blunk, Torsten,
Rachel, Reinhard,
Goepferich, Achim und
Breunig, Miriam
(2012)
Layer-by-Layer Coated Gold Nanoparticles: Size-Dependent Delivery of DNA into Cells.
Small 8 (24), S. 3847-3856.
Volltext nicht vorhanden.
Kees, Martin G.,
Steinke, T.,
Moritz, S.,
Rupprecht, K.,
Paulus, E. M.,
Kees, Frieder K.,
Bucher, M. und
Faerber, L.
(2012)
Omeprazole impairs the absorption of mycophenolate mofetil but not of enteric-coated mycophenolate sodium in healthy volunteers.
Journal of clinical pharmacology 52 (8), S. 1265-1272.
Volltext nicht vorhanden.
Justinger, Christoph,
Schilling, Martin K.,
Kees, Martin G.,
Kauffels, Anne,
Hirschmann, Katrin,
Kopp, Berit,
Kees, Frieder K. und
Kollmar, Otto
(2012)
Penetration of moxifloxacin into liver tissue.
International journal of antimicrobial agents 39 (6), S. 505-509.
Volltext nicht vorhanden.
Heller, Anne,
Brockhoff, Gero und
Goepferich, Achim
(2012)
Targeting drugs to mitochondria.
European Journal of Pharmaceutics and Biopharmaceutics 82, S. 1-18.
Volltext nicht vorhanden.
Klein, Matthias S.,
Dorn, Christoph ,
Saugspier, Michael Sebastian,
Hellerbrand, Claus,
Oefner, Peter J. und
Gronwald, Wolfram
(2011)
Discrimination of steatosis and NASH in mice using nuclear magnetic resonance spectroscopy.
Metabolomics 7 (2), S. 237-246.
Volltext nicht vorhanden.
Kellermann, K.,
Dertinger, N.,
Blobner, M.,
Kees, Frieder,
Kochs, E. F. und
Jungwirt, B.
(2011)
Perioperative moxifloxacin treatment in rats subjected to deep hypothermic circulatory arrest: reduction in cerebral inflammation but without improvement in cognitive performance.
Journal of Thoracic and Cardiovascular Surgery 141 (3), S. 796-802.
Volltext nicht vorhanden.
Gäbele, Erwin,
Dostert, Karin,
Dorn, Christoph ,
Patsenker, Eleonora,
Stickel, Felix und
Hellerbrand, Claus
(2011)
A New Model of Interactive Effects of Alcohol and High-Fat Diet on Hepatic Fibrosis.
Alcoholism: Clinical and Experimental Research 35 (7), S. 1361-1367.
Volltext nicht vorhanden.
Wanninger, Josef,
Neumeier, Markus,
Bauer, Sabrina,
Weiss, Thomas S. ,
Eisinger, Kristina,
Walter, Roland,
Dorn, Christoph ,
Hellerbrand, Claus,
Schäffler, Andreas und
Buechler, Christa
(2011)
Adiponectin induces the transforming growth factor decoy receptor BAMBI in human hepatocytes.
FEBS Letters 585 (9), S. 1338-1344.
Volltext nicht vorhanden.
Kirovski, Georgi,
Dorn, Christoph ,
Huber, Hanna,
Moleda, Lukas,
Niessen, Catrin,
Wobser, Hella,
Schacherer, Doris,
Buechler, Christa,
Wiest, Reiner und
Hellerbrand, Claus
(2011)
Elevated systemic monocyte chemoattractrant protein-1 in hepatic steatosis without significant hepatic inflammation.
Experimental and Molecular Pathology 91 (3), S. 780-783.
Volltext nicht vorhanden.
Schaedlich, A.,
Rose, C.,
Kuntsche, J.,
Caysa, H.,
Mueller, T.,
Goepferich, Achim und
Maeder, K.
(2011)
How Stealthy are PEG-PLA Nanoparticles? An NIR In Vivo Study Combined with Detailed Size Measurements.
Pharmaceutical Research 28 (8), S. 1995-2007.
Volltext nicht vorhanden.
Wanninger, Josef,
Walter, Roland,
Bauer, Sabrina,
Eisinger, Kristina,
Schäffler, Andreas,
Dorn, Christoph ,
Weiss, Thomas S. ,
Hellerbrand, Claus und
Buechler, Christa
(2011)
MMP-9 activity is increased by adiponectin in primary human hepatocytes but even negatively correlates with serum adiponectin in a rodent model of non-alcoholic steatohepatitis.
Experimental and Molecular Pathology 91 (2), S. 603-607.
Volltext nicht vorhanden.
Ferstl, Matthias,
Strasser, Andrea,
Wittmann, Hans-Joachim,
Drechsler, Markus,
Rischer, M.,
Engl, J. und
Goepferich, Achim
(2011)
Nanofibres Resulating from Cooperative Electrostatic and Hydrophobic Interactions between Peptides and Polyelectrolytes of Opposite Charge.
Langmuir 27, S. 14450-14459.
Volltext nicht vorhanden.
Henkel, Janin,
Gärtner, Daniela,
Dorn, Christoph ,
Hellerbrand, Claus,
Schanze, Nancy,
Elz, Sheila R. und
Püschel, Gerhard P.
(2011)
Oncostatin M produced in Kupffer cells in response to PGE2: possible contributor to hepatic insulin resistance and steatosis.
Laboratory Investigation 91 (7), S. 1107-1117.
Volltext nicht vorhanden.
Patsenker, Eleonora,
Schneider, Vreni,
Ledermann, Monika,
Saegesser, Hans,
Dorn, Christoph ,
Hellerbrand, Claus und
Stickel, Felix
(2011)
Potent antifibrotic activity of mTOR inhibitors sirolimus and everolimus but not of cyclosporine A and tacrolimus in experimental liver fibrosis.
Journal of Hepatology 55 (2), S. 388-398.
Volltext nicht vorhanden.
Bauer, Sabrina,
Wanninger, Josef,
Schmidhofer, Sandra,
Weigert, Johanna,
Neumeier, Markus,
Dorn, Christoph ,
Hellerbrand, Claus,
Zimara, Nicole,
Schäffler, Andreas,
Aslanidis, Charalampos und
Buechler, Christa
(2011)
Sterol Regulatory Element-Binding Protein 2 (SREBP2) Activation after Excess Triglyceride Storage Induces Chemerin in Hypertrophic Adipocytes.
Endocrinology 152 (1), S. 26-35.
Volltext nicht vorhanden.
Schaedlich, A.,
Caysa, H.,
Mueller, T.,
Tenambergen, F.,
Rose, Cornelia,
Goepferich, Achim,
Kuntsche, J. und
Maeder, K.
(2011)
Tumor Accumulation of NIR Fluorescent PEG PLA Nanoparticles: Impact of Particle Size and Human Xenograft Tumor Model.
ACS Nano 5, S. 8710-8720.
Volltext nicht vorhanden.
Mathar, I.,
Vennekens, R.,
Meissner, M.,
Kees, Frieder K.,
Van der Mieren, G. und
Camacho Londono, J.
(2010)
Increased catecholamine secretion contributes to hypertension in TRPM4-deficient mice.
The Journal of Clinical Investigation 120 (9), S. 3267-3279.
Volltext nicht vorhanden.
Desch, Matthias,
Schinner, Elisabeth,
Kees, Frieder K.,
Hofmann, F.,
Seifert, Roland und
Schlossmann, Jens
(2010)
Cyclic cytidine 3´,5´-monophosphate (cCMP) signals via cGMP kinase I.
FEBS Letters 584 (18), S. 3979-3984.
Volltext nicht vorhanden.
Kirovski, Georgi,
Gäbele, Erwin,
Dorn, Christoph ,
Moleda, Lukas,
Niessen, Christoph,
Weiss, Thomas S. ,
Wobser, Hella,
Schacherer, Doris,
Buechler, Christa ,
Wasmuth, Hermann E. und
Hellerbrand, Claus
(2010)
Hepatic steatosis causes induction of the chemokine RANTES in the absence of significant hepatic inflammation.
International Journal of Clinical and Experimental Pathology 3 (7), S. 675-680.
Hild, Wolfgang,
Pollinger, Klaus,
Caporale, Andrea,
Cabrele, Chiara,
Keller, Max,
Pluym, Nicola,
Buschauer, Armin ,
Rachel, Reinhard ,
Tessmar, Joerg,
Breunig, Miriam und
Goepferich, Achim
(2010)
G protein-coupled receptors function as logic gates for nanoparticle binding and cell uptake.
Proceedings of the National Academy of Sciences USA: PNAS 107 (23), S. 10667-10672.
Volltext nicht vorhanden.
Desch, Matthias,
Sigl, K.,
Hieke, Bernhard,
Salb, Katharina,
Kees, F. und
Bernhard, D.
(2010)
IRAG determines nitric oxide- and atrial natriuretic peptide-mediated smooth muscle relaxation.
Cardiovascular Research 86 (3), S. 496-505.
Volltext nicht vorhanden.
Dorn, Christoph ,
Riener, Marc-Oliver,
Kirovski, Georgi,
Saugspier, Michael,
Steib, Kathrin,
Weiss, Thomas S. ,
Gäbele, Erwin,
Kristiansen, Glen,
Hartmann, Arndt und
Hellerbrand, Claus
(2010)
Expression of fatty acid synthase in nonalcoholic fatty liver disease.
International Journal of Clinical and Experimental Pathology 3 (5), S. 505-514.
Dietl, Katrin,
Renner, Kathrin,
Dettmer, Katja,
Timischl, Birgit,
Eberhart, Karin,
Dorn, Christoph ,
Hellerbrand, Claus,
Kastenberger, Michael,
Kunz-Schughart, Leoni A.,
Oefner, Peter J.,
Andreesen, Reinhard,
Gottfried, Eva und
Kreutz, Marina
(2010)
Lactic acid and acidification inhibit TNF secretion and glycolysis of human monocytes.
Journal of immunology 184 (3), S. 1200-1209.
Volltext nicht vorhanden.
Brandl, Ferdinand,
Kastner, Fritz,
Gschwind, R. M.,
Blunk, Torsten,
Teßmar, Jörg und
Göpferich, Achim
(2010)
Hydrogel-based drug delivery systems: Comparison of drug diffusivity and release kinetics.
Journal of Controlled Release 142 (2), S. 221-228.
Volltext nicht vorhanden.
Holzhauser, C.,
Berndl, Sina,
Menacher, Florian,
Breunig, Miriam,
Göpferich, Achim und
Wagenknecht, Hans-Achim
(2010)
Synthesis and Optical Properties of Cyanine Dyes as Fluorescent DNA Base Substitutions for Live Cell Imaging.
European Journal of Organic Chemistry (7), S. 1239-1248.
Volltext nicht vorhanden.
Dorn, Christoph ,
Kraus, Birgit,
Motyl, Magdalena,
Weiss, Thomas S. ,
Gehrig, Manfred,
Schoelmerich, Juergen,
Heilmann, Jörg und
Hellerbrand, Claus
(2010)
Xanthohumol, a chalcon derived from hops, inhibits hepatic inflammation and fibrosis.
Molecular nutrition & food research 54 (Suppl.), S205-S213.
Volltext nicht vorhanden.
Dorn, Christoph ,
Weiss, Thomas S. ,
Heilmann, Jörg und
Hellerbrand, Claus
(2010)
Xanthohumol, a prenylated chalcone derived from hops, inhibits proliferation, migration and interleukin-8 expression of hepatocellular carcinoma cells.
International journal of oncology 36 (2), S. 435-441.
Volltext nicht vorhanden.
Arndt, Stephanie,
Mägdefrau, Ulrike,
Dorn, Christoph ,
Schardt, Katharina,
Hellerbrand, Claus und
Bosserhoff, Anja–Katrin
(2009)
Iron-Induced Expression of Bone Morphogenic Protein 6 in Intestinal Cells Is the Main Regulator of Hepatic Hepcidin Expression In Vivo.
Gastroenterology 138 (1), S. 372-382.
Volltext nicht vorhanden.
Weiser, Barbara,
Sommer, Florian,
Neubauer, M.,
Seitz, Anna Katharina,
Teßmar, Jörg,
Göpferich, Achim und
Blunk, Torsten
(2009)
Ascorbic Acid Enhances Adipogenesis of Bone Marrow-Derived Mesenchymal Stromal Cells.
Cells Tissues Organs 189 (6), S. 373-381.
Volltext nicht vorhanden.
Beule, A. G.,
Steinmeier, E.,
Kaftan, H.,
Biebler, K.-E.,
Göpferich, Achim,
Wolf, Eva und
Hosemann, W.
(2009)
Effects of a dexamethasone-releasing stent on osteoneogenesis in a rabbit model.
American journal of rhinology & allergy 23 (4), S. 433-436.
Volltext nicht vorhanden.
Sommer, Florian,
Brandl, Ferdinand,
Weiser, Barbara,
Teßmar, Jörg,
Blunk, Torsten und
Göpferich, Achim
(2009)
FACS as useful tool to study distinct hyalocyte populations.
Experimental Eye Research 88 (5), S. 995-999.
Volltext nicht vorhanden.
Elbakry, Asmaa,
Zaky, A.,
Liebl, Renate,
Rachel, Reinhard,
Göpferich, Achim und
Breunig, Miriam
(2009)
Layer-by-Layer Assembled Gold Nanoparticles for siRNA Delivery.
Nano Letters 9 (5), S. 2059-2064.
Volltext nicht vorhanden.
Wobser, Hella,
Dorn, Christoph ,
Weiss, Thomas S. ,
Amann, Thomas,
Bollheimer, Cornelius,
Büttner, Roland,
Schölmerich, Jürgen und
Hellerbrand, Claus
(2009)
Lipid accumulation in hepatocytes induces fibrogenic activation of hepatic stellate cells.
Cell Research 19 (8), S. 996-1005.
Volltext nicht vorhanden.
Appel, Bernhard,
Baumer, Julia,
Eyrich, Daniela,
Sarhan, Hatem,
Taso, S.,
Englert, Carsten und
Göpferich, Achim
(2009)
Synergistic effects of growth and differentiation factor-5 (GDF-5) and insulin on expanded chondrocytes in a 3-D environment.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 17 (11), S. 1503-1512.
Volltext nicht vorhanden.
Koelwel, C.,
Rothschenk, Stefan,
Fuchs-Koelwel, B.,
Gabler, B.,
Lohmann, C. und
Göpferich, Achim
(2008)
Alginate inserts loaded with epidermal growth factor for the treatment of keratoconjunctivitis sicca.
Pharmaceutical Development and Technology 13 (3), S. 221-231.
Volltext nicht vorhanden.
Beule, A. G.,
Scharf, C.,
Biebler, K.-E.,
Göpferich, Achim,
Steinmeier, E.,
Wolf, E.,
Hosemann, W. und
Kaftan, H.
(2008)
Effects of Topically Applied Dexamethasone on Mucosal Wound Healing Using a Drug-Releasing Stent.
The Laryngoscope 118 (11), S. 2073-2077.
Volltext nicht vorhanden.
Sommer, Florian,
Pollinger, Klaus,
Brandl, Ferdinand,
Weiser, Barbara,
Teßmar, Jörg,
Blunk, Torsten und
Göpferich, Achim
(2008)
Hyalocyte proliferation and ECM accumulation modulated by bFGF and TGF-β1.
Graefe's Archive for Clinical and Experimental Ophthalmology 246 (9), S. 1275-1284.
Volltext nicht vorhanden.
Weiser, Barbara,
Prantl, Lukas,
Schubert, Thomas E. O.,
Zellner, J.,
Fischbach-Teschl, Claudia,
Spruss, Thilo,
Seitz, Anna Katharina,
Teßmar, Jörg,
Göpferich, Achim und
Blunk, Torsten
(2008)
In Vivo Development and Long-Term Survival of Engineered Adipose Tissue Depend on In Vitro Precultivation Strategy.
Tissue Engineering Part A 14 (2), S. 275-284.
Volltext nicht vorhanden.
Breunig, Miriam,
Hosza, C.,
Lungwitz, Uta,
Watanabe, K.,
Umeda, I.,
Kato, H. und
Göpferich, Achim
(2008)
Mechanistic investigation of poly(ethylene imine)-based siRNA delivery: Disulfide bonds boost intracellular release of the cargo.
Journal of Controlled Release 130 (1), S. 57-63.
Volltext nicht vorhanden.
Gäbele, Erwin,
Mühlbauer, Marcus,
Dorn, Christoph ,
Weiss, Thomas S. ,
Froh, Matthias,
Schnabl, Bernd,
Wiest, Reiner,
Schölmerich, Jürgen,
Obermeier, Florian und
Hellerbrand, Claus
(2008)
Role of TLR9 in hepatic stellate cells and experimental liver fibrosis.
Biochemical and Biophysical Research Communications 376 (2), S. 271-276.
Volltext nicht vorhanden.
Preuss, Hendrik,
Ghorai, Prasanta,
Kraus, Anja,
Dove, Stefan,
Buschauer, Armin und
Seifert, Roland
(2007)
Point Mutations in the Second Extracellular Loop of the Histamine H2 Receptor do not affect the Species-Selective Activity of Guanidine-Type Agonists.
Naunyn Schmiedebergs Arch. Pharmacol. 376 (4), S. 253-264.
Zugang zum Volltext eingeschränkt.
Hagelüken, A.,
Grünbaum, L.,
Nürnberg, B.,
Harhammer, R.,
Schunack, W. und
Seifert, Roland
(1994)
Lipophilic beta-adrenoceptor antagonists and local anesthetics are effective direct activators of G-proteins.
Biochemical pharmacology 47 (10), S. 1789-1795.
Klinker, J. F.,
Hagelüken, A.,
Grünbaum, L.,
Heilmann, I.,
Nürnberg, B.,
Harhammer, R.,
Offermanns, S.,
Schwaner, I.,
Ervens, J.,
Wenzel-Seifert, K.,
Müller, T. und
Seifert, Roland
(1994)
Mastoparan may activate GTP hydrolysis by Gi-proteins in HL-60 membranes indirectly through interaction with nucleoside diphosphate kinase.
The Biochemical journal 304 ( Pt 2, S. 377-383.
Seifert, Roland,
Hagelüken, A.,
Höer, A.,
Höer, D.,
Grünbaum, L.,
Offermanns, S.,
Schwaner, I.,
Zingel, V.,
Schunack, W. und
Schultz, Günter
(1994)
The H1 receptor agonist 2-(3-chlorophenyl)histamine activates Gi proteins in HL-60 cells through a mechanism that is independent of known histamine receptor subtypes.
Molecular Pharmacology 45 (4), S. 578-586.
Tsang, K. W.,
Roberts, P.,
Read, R. C.,
Kees, Frieder,
Wilson, R. und
Cole, P. J.
(1994)
The concentrations of clarithromycin and its 14-hydroxy metabolite in sputum of patients with bronchiectasis following single dose oral administration.
The Journal of antimicrobial chemotherapy 33 (2), S. 289-297.
Klinker, J. F.,
Höer, A.,
Schwaner, I.,
Offermanns, S.,
Wenzel-Seifert, Katharina und
Seifert, Roland
(1993)
Lipopeptides activate Gi-proteins in dibutyryl cyclic AMP-differentiated HL-60 cells.
The Biochemical journaL 296 ( Pt 1, S. 245-251.
Klinz, F. J.,
Seifert, Roland,
Schwaner, I.,
Gausepohl, H.,
Frank, R. und
Schultz, Günter
(1992)
Generation of specific antibodies against the rap1A, rap1B and rap2 small GTP-binding proteins. Analysis of rap and ras proteins in membranes from mammalian cells.
European journal of biochemistry 207 (1), S. 207-213.
Seifert, Roland,
Serke, S.,
Huhn, D.,
Bessler, W. G.,
Hauschildt, S.,
Metzger, J.,
Wismüller, K. H. und
Jung, G.
(1992)
Incomplete functional differentiation of HL-60 leukemic cells by synthetic lipopeptides. Partial inhibition by pertussis toxin of enhanced superoxide formation.
European journal of biochemistry / FEBS 203 (1-2), S. 143-151.
Offermanns, S.,
Seifert, Roland,
Metzger, J. W.,
Jung, G.,
Lieberknecht, A.,
Schmidt, U. und
Schultz, Günter
(1992)
Lipopeptides are effective stimulators of tyrosine phosphorylation in human myeloid cells.
Biochemical Journal 282 ( Pt 2, S. 551-7.
Seifert, Roland,
Schultz, Günter,
Richter-Freund, M.,
Metzger, J.,
Wiesmüller, K. H.,
Jung, G.,
Bessler, W. G. und
Hauschildt, S.
(1990)
Activation of superoxide formation and lysozyme release in human neutrophils by the synthetic lipopeptide Pam3Cys-Ser-(Lys)4. Involvement of guanine-nucleotide-binding proteins and synergism with chemotactic peptides.
The Biochemical journal 267 (3), S. 795-802.
Naber, K. G.,
Sörgel, F.,
Kees, Frieder K.,
Schumacher, H.,
Sigl, G.,
Zürcher, J. und
Berger, S.
(1989)
Enoxacin-Konzentrationen in der Samenflüssigkeit, im Prostatasekret und im Prostataadenomgewebe nach oraler Gabe oder intravenöser Infusion [Enoxacin concentration in seminal fluid, in prostate secretions and in prostatic adenoma tissue following oral administration or intravenous infusion].
Infection 17 Suppl 1, S30-S66.
Rudolph, U.,
Koesling, D.,
Hinsch, K. D.,
Seifert, Roland,
Bigalke, M.,
Schultz, Günter und
Rosenthal, W.
(1989)
G-protein alpha-subunits in cytosolic and membranous fractions of human neutrophils.
Molecular and cellular endocrinology 63 (1-2), S. 143-153.
Naber, K. G.,
Sörgel, F.,
Kees, Frieder K.,
Jaehde, U. und
Schumacher, H.
(1989)
Pharmacokinetics of ciprofloxacin in young (healthy volunteers) and elderly patients, and concentrations in prostatic fluid, seminal fluid, and prostatic adenoma tissue following intravenous administration.
The American journal of medicine 87 (5supl1), S57-S59.
Naber, K. G.,
Sörgel, F.,
Kees, Frieder K.,
Schumacher, H.,
Metz, R. und
Grobecker, H.
(1988)
In-vitro activity of fleroxacin against isolates causing complicated urinary tract infections and concentrations in seminal and prostatic fluid and in prostatic adenoma tissue.
The Journal of antimicrobial chemotherapy 22 Suppl D, S. 199-207.
Seifert, Roland,
Rosenthal, W.,
Schultz, Günter,
Wieland, T.,
Gierschick, P. und
Jakobs, K. H.
(1988)
The role of nucleoside-diphosphate kinase reactions in G protein activation of NADPH oxidase by guanine and adenine nucleotides.
European journal of biochemistry / FEBS 175 (1), S. 51-55.
Naber, K.,
Kees, Frieder K.,
Denk, K.,
Bauernfeind, A. und
Grobecker, H.
(1987)
Carumonam versus ceftazidime: in vitro activity, pharmacokinetics in elderly patients, safety and therapeutic efficacy in the treatment of complicated urinary tract infections.
Chemioterapia 6 (2 Supl), S. 517-518.
Volltext nicht vorhanden.
Grobecker, H.,
Kees, Frieder K.,
Linden, M.,
Schrader, E. und
Welte, S.
(1987)
Untersuchungen zur Bioverfügbarkeit von Midodrin und 2,5- Dimethoxyphenyl-ß-aminoethanol-hydrochlorid [The bioavailability of midodrin and alpha-2,5-dimethoxyphenyl-beta-aminoethanol hydrochloride].
Arzneimittel-Forschung 37 (4), S. 447-450.
Naber, K. G.,
Dette, G. A.,
Kees, Frieder K.,
Knothe, H. und
Grobecker, H.
(1986)
Pharmacokinetics, in-vitro activity, therapeutic efficacy and clinical safety of aztreonam vs. cefotaxime in the treatment of complicated urinary tract infections.
The Journal of antimicrobial chemotherapy 17 (4), S. 517-527.
Grobecker, H.,
Gessler, I.,
Delius, W.,
Dominiak, P. und
Kees, Frieder K.
(1985)
Effect of ketanserin on hemodynamics, plasma-catecholamine concentrations, and serotonin uptake by platelets in volunteers and patients with congestive heart failure.
Journal of cardiovascular pharmacology 7, Suppl 7, S102-S104.
Kees, Frieder K.,
Naber, K. G.,
Bartoschik-Wich, B.,
Stockmann, P.,
Meyer, G. P. und
Grobecker, H.
(1985)
High-performance liquid chromatography analysis of mezlocillin, piperacillin, their degradation products, and of ioxitalamic acid in plasma and urine of healthy volunteers.
Arzneimittel-Forschung 35 (7), S. 1099-1104.
Kees, Frieder K.,
Strehl, E.,
Dominiak, P.,
Grobecker, H.,
Seeger, K.,
Seidel, G.,
Neuhaus, B. und
Safrany, L.
(1983)
Cefotaxime and desacetyl cefotaxime in human bile.
Infection 11 (2), S. 118-120.
Kees, Frieder K.,
Strehl, E.,
Seeger, K.,
Seidel, G.,
Dominiak, P. und
Grobecker, H.
(1981)
Comparative determination of cefotaxime and desacetyl cefotaxime in serum and bile by bioassay and high-performance liquid chromatography.
Arzneimittel-Forschung 31 (2), S. 362-365.
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