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Number of items at this level: 1167.

Ertl, Fabian J., Friedel, Anna, Schmid, Elena J., Höring, Carina , Archipowa, Nataliya , Koch, Pierre , Maschauer, Simone, Kutta, Roger Jan , Prante, Olaf and Keller, Max (2025) High-Affinity and Proteolytically Stable Peptidic Fluorescent NTS1R Ligands. Journal of Medicinal Chemistry.

Gruber, Thomas Olaf (2025) Chemotaxonomisches Screening von zwölf Spezies der Gattung Salix und Untersuchung des phenolischen Sekundärstoffspektrums von Salix cinerea L. PhD, Universität Regensburg.

Damm, Carsten and Goepferich, Achim (2025) Dual cross-linked hydrogels as promising materials for drug delivery. International Journal of Pharmaceutics 683, p. 125929.

Remmert, Marius, Konrad, Johannes , Birringer, Jan and Goepferich, Achim (2025) Interferon gamma modifies nanoparticle tropism and cell uptake. Journal of Drug Delivery Science and Technology 113, p. 107301.

Mönnich, Denise (2025) Characterization of Monomers and Heteromers of the Dopamine and Histamine Receptor Families Using Bioluminescence- and Radioactivity-Based Techniques. PhD, Universität Regensburg.

Sellmer, Andreas, Able, Marina, Spiekermann, Karsten, Reinecke, Maria, Kuster, Bernhard, Utpatel, Kirsten , Wirth, Lukas, Pongratz, Herwig, Plank, Nicole, Koch, Pierre , Elz, Sigurd, Fischer, Amrei, Tizazu, Belay, Fiebig, Heinz-Herbert, Dove, Stefan and Mahboobi, Siavosh (2025) Novel water-soluble and highly efficient dual type I/II next generation inhibitors of FMS-like tyrosine kinase 3 (FLT3). European Journal of Medicinal Chemistry 296, p. 117849.

Seibel-Ehlert, Ulla (2025) Development and Application of Label-free and Label-dependent Assays for Functional Characterization of Histamine Receptors and Ligands. PhD, Universität Regensburg.

Nothofer, Stefanie, Haselbeck-Koebler, Michael, Zeitlinger, Markus, Dorn, Christoph , Petroff, David, Wrigge, Hermann, Dumps, Christian, Heller, Axel R. and Simon, Philipp (2025) Surgical Antibiotic Prophylaxis Dosing in Adult Patients with Obesity: A Comprehensive Review of Pharmacokinetic and Pharmacodynamic Data. Anesthesiology 142 (5), pp. 929-948. Fulltext not available.

Stommel, Alexandra-Maria , Matzneller, Peter, al Jalali, Valentin, Wulkersdorfer, Beatrix, Lackner, Edith, Mueller, Matthias, Dorn, Christoph , Holzer, Michael and Zeitlinger, Markus (2025) Impact of Hypothermic Temperature Control on Plasma and Soft Tissue Pharmacokinetics of Penicillin/Beta-Lactamase Inhibitor Combinations in Patients Resuscitated After Cardiac Arrest. Clinical Pharmacokinetics.

Lier, Constantin, Kees, Frieder , Witowski, Andrea, Rahmel, Tim, Pockes, Steffen and Dorn, Christoph (2025) Simultaneous determination of ceftazidime and avibactam in patients by isocratic ion-pair liquid chromatography with photometric detection. Journal of Chromatography Open 7, p. 100212.

Ahmed, Hifza, Dorn, Christoph and Zeitlinger, Markus (2025) Interspecies differences in Plasma Protein Binding of Beta-Lactam Antibiotics. International Journal of Antimicrobial Agents, p. 107476.

Bindellini, Davide, Simon, Philipp, Busse, David, Michelet, Robin, Petroff, David, Aulin, Linda B. S., Dorn, Christoph , Zeitlinger, Markus, Huisinga, Wilhelm, Wrigge, Hermann and Kloft, Charlotte (2025) Evaluation of the need for dosing adaptations in obese patients for surgical antibiotic prophylaxis: a model-based analysis of cefazolin pharmacokinetics. British Journal of Anaesthesia.

Bresinsky, Melanie (2025) Nanoparticles Mimicking Viral Infections: Novel Approaches for Targeted Drug Delivery. PhD, Universität Regensburg.

Zimmer, Oliver (2025) Contributions to the Fundamental Understanding of Nanoparticle Cell Interactions and Target-Specific Biodistribution. PhD, Universität Regensburg.

Bresinsky, Melanie and Goepferich, Achim (2025) Control of biomedical nanoparticle distribution and drug release in vivo by complex particle design strategies. European Journal of Pharmaceutics and Biopharmaceutics 208, p. 114634.

Müller, Christoph (2024) Structure-based development of nonpeptidic fluorescent probes, PET tracers and homobivalent neuropeptide Y Y1 receptor ligands with picomolar binding affinities. PhD, Universität Regensburg.

Gonzalez-Valerio, Carlos, Peregrina-Lucano, Alejandro A. , Manríquez-González, Ricardo, Pérez-Fonseca, Aida A., Robledo-Ortíz, Jorge R., Shenderovich, Ilya G. and Gómez-Salazar, Sergio (2024) Color Compounds Removal from Tequila Vinasses Using Silica Gel Adsorbents Functionalized with Thiol Moieties: Equilibrium and Kinetics Studies. Molecules 29 (24), p. 5910.

Becker, Jasmin, Ellerkmann, Clara S., Schmelzer, Hannah, Hermann, Christian, Lützel, Kyra, Gudermann, Thomas, Konrad, David B., Trauner, Dirk, Storch, Ursula and Mederos y Schnitzler, Michael (2024) Optical Control of TRPM8 Channels with Photoswitchable Menthol. Angewandte Chemie International Edition.

Dejaco, Alexander , Dorn, Christoph , Lier, Constantin, Fleischmann, Daniel, Kratzer, Alexander, Habler, Katharina, Paal, Michael, Gruber, Michael , Rosenberger, Johanna and Kees, Martin G. (2024) Target-controlled dialysis for antibiotics (TCD-ABx). Intensive Care Medicine Experimental 12, p. 108.

Ferrando Plo, Lucas , Nitsopoulos, Athanasios, Friedle, Albrecht, Schmidberger, Andreas and Heilmann, Jörg (2024) Anthraquinone Residues in Dried Walnut (Juglans regia) Leaves for Herbal Infusions: Proof of Endogenous Origin via a Sampling-Driven and GC-MS/MS-Based Strategy. Journal of Agricultural and Food Chemistry 72 (48), pp. 26915-26925.

Lang, Johannes, Schorr, Kathrin and Goepferich, Achim (2024) Towards a switchable nanoparticle behavior using inverse electron-demand Diels-Alder chemistry and ectoenzyme-based ligand activation. European Journal of Pharmaceutical Sciences 204, p. 106944.

Witowski, Andrea, Palmowski, Lars, Minichmayr, Iris K., Zeitlinger, Markus, Dorn, Christoph , Lier, Constantin, Adamzik, Michael, Nowak, Hartmuth and Rahmel, Tim (2024) Concentrations of ceftazidime and avibactam in bile fluid—a prospective phase IIb study. Journal of Antimicrobial Chemotherapy 79 (12), pp. 3297-3302. Fulltext not available.

Sanz-Codina, Maria, van Os, Wisse, Pham, Anh Duc, Jorda, Anselm, Wölf-Duchek, Michael, Bergmann, Felix, Lackner, Edith, Lier, Constantin, Coen van Hasselt, J. G., Minichmayr, Iris K., Dorn, Christoph , Zeitlinger, Markus and al Jalali, Valentin (2024) Target-site cefiderocol pharmacokinetics in soft tissues of healthy volunteers. Journal of Antimicrobial Chemotherapy 79 (12), pp. 3281-3288.

Unterholzner, Anna (2024) Isolierung terpenoider Sekundärstoffe und eines Lignans aus dem Harz von C. myrrha und deren pharmakologische in vitro Testung in Inflammationsmodellen. PhD, Universität Regensburg.

Unterholzner, Anna, Kuck, Katrin, Weinzierl, Anna, Lipowicz, Bartosz and Heilmann, Jörg (2024) An Unprecedented 4,8-Cycloeudesmane, Further New Sesquiterpenoids, a Triterpene, Steroids, and a Lignan from the Resin of Commiphora myrrha and Their Anti-Inflammatory Activity In Vitro. Molecules 29 (18), p. 4315.

Schorr, Kathrin, Chen, Xinyu, Sasaki, Takanori, Arias-Loza, Anahi Paula, Lang, Johannes, Higuchi, Takahiro and Goepferich, Achim (2024) Rethinking Thin-Layer Chromatography for Screening Technetium-99m Radiolabeled Polymer Nanoparticles. ACS Pharmacology & Translational Science 7 (9), pp. 2604-2611.

Schatz, Lea Marie, Greppmair, Sebastian, Kunzelmann, Alexandra K., Starp, Johannes, Brinkmann, Alexander, Roehr, Anka, Frey, Otto, Hagel, Stefan, Dorn, Christoph , Zoller, Michael, Scharf, Christina, Wicha, Sebastian G. and Liebchen, Uwe (2024) Predictive performance of multi-model approaches for model-informed precision dosing of piperacillin in critically ill patients. International Journal of Antimicrobial Agents 64 (4), p. 107305.

Brummer, Christina, Singer, Katrin, Brand, Almut, Bruss, Christina, Renner, Kathrin, Herr, Wolfgang, Pukrop, Tobias, Dorn, Christoph , Hellerbrand, Claus, Matos, Carina and Kreutz, Marina (2024) Sex-Dependent T Cell Dysregulation in Mice with Diet-Induced Obesity. International Journal of Molecular Sciences 25 (15), p. 8234.

Lier, Constantin, Dejaco, Alexander , Kratzer, Alexander, Kees, Martin G. , Kees, Frieder and Dorn, Christoph (2024) Free serum concentrations of antibiotics determined by ultrafiltration: extensive evaluation of experimental variables. Bioanalysis, pp. 1-10. Fulltext not available.

Scheuerer, Simon (2024) Selektive HDAC6-Inhibitoren und „Proteolysis Targeting Chimeras“ (PROTACs): Synthese und biologische Testung. PhD, Universität Regensburg.

Walter, Melanie, Bresinsky, Merlin, Zimmer, Oliver , Pockes, Steffen and Goepferich, Achim (2024) Conditional Cell-Penetrating Peptide Exposure as Selective Nanoparticle Uptake Signal. ACS Applied Materials & Interfaces 16 (29), pp. 37734-37747.

Scheuerer, Simon, Motlova, Lucia, Schäker-Hübner, Linda, Sellmer, Andreas, Feller, Felix, Ertl, Fabian J., Koch, Pierre , Hansen, Finn K., Barinka, Cyril and Mahboobi, Siavosh (2024) Biological and structural investigation of tetrahydro-β-carboline-based selective HDAC6 inhibitors with improved stability. European Journal of Medicinal Chemistry 276, p. 116676.

Mietzner, Raphael , Barbey, Clara, Lehr, Heike, Ziegler, Christian E., Peterhoff, David , Wagner, Ralf , Goepferich, Achim and Breunig, Miriam (2024) Prolonged delivery of HIV-1 vaccine nanoparticles from hydrogels. International Journal of Pharmaceutics 657, p. 124131.

Zimmer, Oliver and Goepferich, Achim (2024) On the uncertainty of the correlation between nanoparticle avidity and biodistribution. European Journal of Pharmaceutics and Biopharmaceutics 198, p. 114240.

Hosmann, Arthur, Moser, Miriam M, van Os, Wisse, Gramms, Leon, al Jalali, Valentin, Sanz Codina, Maria, Plöchl, Walter, Lier, Constantin, Kees, Frieder , Dorn, Christoph , Rössler, Karl, Reinprecht, Andrea and Zeitlinger, Markus (2024) Linezolid brain penetration in neurointensive care patients. Journal of Antimicrobial Chemotherapy, dkae025.

Beck, Sebastian (2024) Core-Shell Nanoparticles as a Platform Technology for the Treatment of Proliferative Ocular Diseases. PhD, Universität Regensburg.

Dejaco, Alexander , Dorn, Christoph , Paal, Michael, Gruber, Michael , Graf, Bernhard M. and Kees, Martin G. (2024) Determination of glomerular filtration rate “en passant” after high doses of iohexol for computed tomography in intensive care medicine—a proof of concept. Frontiers in Pharmacology 15.

Haase, André, Miroschnikov, Natalia, Klein, Stefan, Doege, Annika, Dünker, Nicole, Van Meenen, Dario, Junker, Andreas, Göpferich, Achim , Apaolaza, P. S. and Busch, Maike Anna (2024) New retinoblastoma (RB) drug delivery approaches: anti-tumor effect of atrial natriuretic peptide (ANP)-conjugated hyaluronic-acid-coated gold nanoparticles for intraocular treatment of chemoresistant RB. Molecular Oncology 18 (4), pp. 832-849. Fulltext not available.

Grafakou, Maria-Eleni, Barda, Christina, Skaltsa, Helen and Heilmann, Joerg (2024) Study on the metabolism of natural sesquiterpene lactones in human liver microsomes using LC-Q-TOF-MS/MS. Natural Product Research 38 (11), pp. 1855-1863. Fulltext not available.

Wulkersdorfer, Beatrix, Bergmann, Felix, Amann, Lisa, Fochtmann-Frana, Alexandra, Al Jalali, Valentin, Kurdina, Elizaveta, Lackner, Edith, Wicha, Sebastian G, Dorn, Christoph , Schäfer, Bruno, Ihra, Gerald, Rath, Thomas, Radtke, Christine and Zeitlinger, Markus (2023) Effect of albumin substitution on pharmacokinetics of piperacillin/tazobactam in patients with severe burn injury admitted to the ICU. Journal of Antimicrobial Chemotherapy.

Nagl, Martin, Moennich, Denise, Rosier, Niklas , Schihada, Hannes, Sirbu, Alexei, Konar, Nergis, Reyes-Resina, Irene, Navarro, Gemma, Franco, Rafael, Kolb, Peter, Annibale, Paolo and Pockes, Steffen (2023) Fluorescent Tools for the Imaging of Dopamine D2‐Like Receptors. ChemBioChem.

Rosier, Niklas , Moennich, Denise, Nagl, Martin, Schihada, Hannes, Sirbu, Alexei, Konar, Nergis, Reyes-Resina, Irene, Navarro, Gemma, Franco, Rafael, Kolb, Peter, Annibale, Paolo and Pockes, Steffen (2023) Shedding Light on the D1‐Like Receptors: A Fluorescence‐Based Toolbox for Visualization of the D1 and D5 Receptors. ChemBioChem.

Stahl, Monika (2023) Polymeric Nanoparticles for Antigen Delivery to Dendritic Cells. PhD, Universität Regensburg.

Bürkel, Peter, Rajbhandari, Meena and Jürgenliemk, Guido (2023) Bassia longifolia (= Madhuca longifolia): Isolation of flavan-3-ols and their contribution to the antibacterial and antidiabetic activity in vitro. Heliyon 9 (11), e21134.

Höring, Carina (2023) Split-Luciferase Complementation and Molecular Dynamics Studies for the Mini-G Protein-Based Functional Characterization of GPCRs. PhD, Universität Regensburg.

Geiben, Ann-Kathrin Christine Maria (2023) Analyse von Sedierung als unerwünschte Arzneimittelwirkung und Entwicklung eines Risikoscores für die Gerontopsychiatrie. PhD, Universität Regensburg.

Greppmair, Sebastian, Brinkmann, Alexander, Roehr, Anka, Frey, Otto, Hagel, Stefan, Dorn, Christoph , Marsot, Amélie, El-Haffaf, Ibrahim, Zoller, Michael, Saller, Thomas, Zander, Johannes, Schatz, Lea Marie, Scharf, Christina, Briegel, Josef, Minichmayr, Iris K., Wicha, Sebastian G. and Liebchen, Uwe (2023) Towards model-informed precision dosing of piperacillin: multicenter systematic external evaluation of pharmacokinetic models in critically ill adults with a focus on Bayesian forecasting. Intensive Care Medicine.

Serra, Alessandra , Mozgunov, Pavel, Davies, Geraint and Jaki, Thomas (2023) Determining the minimum duration of treatment in tuberculosis: An order restricted non‐inferiority trial design. Pharmaceutical Statistics 22 (5), pp. 938-962.

Prüschenk, Sally , Majer, Michael and Schlossmann, Jens (2023) Novel Functional Features of cGMP Substrate Proteins IRAG1 and IRAG2. International Journal of Molecular Sciences 24 (12), p. 9837.

Ziegler, Christian (2023) Development of Injectable Anhydrous Hydrogels for the Controlled Release of Therapeutic Proteins. PhD, Universität Regensburg.

Bohley, Marilena , Dillinger, Andrea E., Braunger, Barbara M., Tamm, Ernst R. and Goepferich, Achim (2023) Intravenous injection of cyclosporin A loaded lipid nanocapsules fights inflammation and immune system activation in a mouse model of diabetic retinopathy. Drug Delivery and Translational Research 13, pp. 2807-2818.

Chen, Zhendong , Taubert, Max, Chen, Chunli , Dokos, Charalambos, Fuhr, Uwe, Weig, Thomas, Zoller, Michael, Heck, Suzette, Dimitriadis, Konstantinos , Terpolilli, Nicole, Kinast, Christina, Scharf, Christina, Lier, Constantin, Dorn, Christoph and Liebchen, Uwe (2023) Plasma and Cerebrospinal Fluid Population Pharmacokinetics of Vancomycin in Patients with External Ventricular Drain. Antimicrobial Agents and Chemotherapy. Fulltext not available.

Wirth, Ulrike, Erl, Julia, Azzam, Saphia, Hoering, Carina, Skiba, Michael, Singh, Ritu, Hochmuth, Kathrin, Keller, Max, Wegener, Joachim and König, Burkhard (2023) Monitoring the Reversibility of GPCR Signaling by Combining Photochromic Ligands with Label-free Impedance Analysis. Angewandte Chemie International Edition, e202215547.

Grätz, Lukas (2023) Luminescence-based methods for the investigation of ligand binding and GRK2 recruitment to GPCRs. PhD, Universität Regensburg.

Hoffelner, Beate Sandra, Andreev, Stanislav , Plank, Nicole and Koch, Pierre (2023) Photocaging of Pyridinylimidazole-Based Covalent JNK3 Inhibitors Affords Spatiotemporal Control of the Binding Affinity in Live Cells. Pharmaceuticals 16 (2), p. 264.

Prüschenk, Sally (2023) Molekulare und physiologische Funktion von IRAG2 in Thrombozyten und im Pankreas. PhD, Universität Regensburg.

Haen, Ekkehard (2023) Arzneimittelwechselwirkungen – wie kann man sich vor der Informationsflut schützen? Die Innere Medizin 64 (1), pp. 93-101. Fulltext not available.

Kuzo, Nazar, Haen, Ekkehard, Ho, Dominic M., Takeuchi, Hiroyoshi, Piras, Marianna, Eap, Chin-Bin, de Filippis, Renato, Homan, Philipp, Kane, John M., Roy, Marc-André, Paulzen, Michael and Schoretsanitis, Georgios (2023) Clozapine once- versus multiple-daily dosing: a two-center cross-sectional study, systematic review and meta-analysis. European Archives of Psychiatry and Clinical Neuroscience 273 (7), pp. 1567-1578. Fulltext not available.

Bresinsky, Merlin, Shahraki, Aida , Kolb, Peter , Pockes, Steffen and Schihada, Hannes (2023) Development of Fluorescent AF64394 Analogues Enables Real-Time Binding Studies for the Orphan Class A GPCR GPR3. Journal of Medicinal Chemistry 66 (21), pp. 15025-15041. Fulltext not available.

Margraff, Teresa, Schoretsanitis, Georgios , Neuner, Irene, Haen, Ekkehard, Gaebler, Arnim Johannes and Paulzen, Michael (2023) Discovering interactions in augmentation strategies: Impact of duloxetine on the metabolism of aripiprazole. Basic & Clinical Pharmacology & Toxicology 133 (1), pp. 73-81. Fulltext not available.

Mönnich, Denise, Nagl, Martin, Forster, Lisa, Rosier, Niklas, Igel, Patrick and Pockes, Steffen (2023) Discovery of a Tritiated Radioligand with High Affinity and Selectivity for the Histamine H3 Receptor. ACS Medicinal Chemistry Letters 14 (11), pp. 1589-1595. Fulltext not available.

Szczepańska, Katarzyna, Karcz, Tadeusz, Dichiara, Maria, Mogilski, Szczepan, Kalinowska-Tłuścik, Justyna, Pilarski, Bogusław, Leniak, Arkadiusz, Pietruś, Wojciech , Podlewska, Sabina , Popiołek-Barczyk, Katarzyna, Humphrys, Laura J. , Ruiz-Cantero, M. Carmen, Reiner-Link, David , Leitzbach, Luisa, Łażewska, Dorota, Pockes, Steffen , Górka, Michał, Zmysłowski, Adam, Calmels, Thierry, Cobos, Enrique J., Marrazzo, Agostino, Stark, Holger, Bojarski, Andrzej J., Amata, Emanuele and Kieć-Kononowicz, Katarzyna (2023) Dual Piperidine-Based Histamine H3 and Sigma-1 Receptor Ligands in the Treatment of Nociceptive and Neuropathic Pain. Journal of Medicinal Chemistry 66 (14), pp. 9658-9683. Fulltext not available.

Walter, Melanie, Baumann, Felix, Schorr, Kathrin and Goepferich, Achim (2023) Ectoenzymes as promising cell identification structures for the high avidity targeting of polymeric nanoparticles. International Journal of Pharmaceutics 647, p. 123453. Fulltext not available.

Jacob, Hannes, Braekow, Pauline, Hofmann, Britt, Kirchhefer, Uwe, Forster, Lisa, Mönnich, Denise, Humphrys, Laura J., Pockes, Steffen, Neumann, Joachim and Gergs, Ulrich (2023) Ergometrine stimulates histamine H2 receptors in the isolated human atrium. Naunyn-Schmiedeberg's Archives of Pharmacology 396 (12), pp. 3809-3822. Fulltext not available.

Kolev, Iliyan, Dimova, Tanya, Iliev, Ivan, Rogozherov, Marin and Bodensteiner, Michael (2023) Further findings concerning 2,6-diiodo-3,4,5-trimethoxybenzoic acid (Part II). Journal of Molecular Structure 1294, p. 136388. Fulltext not available.

Zimmer, Oliver and Goepferich, Achim (2023) How clathrin-coated pits control nanoparticle avidity for cells. Nanoscale Horizons 8 (2), pp. 256-269. Fulltext not available.

Zimmer, Oliver, Walter, Melanie, Remmert, Marius, Maier, Olga, Witzgall, Ralph and Goepferich, Achim (2023) Impact of interferon-γ on the target cell tropism of nanoparticles. Journal of Controlled Release 362, pp. 325-341. Fulltext not available.

Gaebler, Arnim Johannes , Haen, Ekkehard, Omar, Nagia Ben, Endres, Katharina, Hiemke, Christoph, Schoretsanitis, Georgios and Paulzen, Michael (2023) Lower sertraline plasma concentration in patients co‐medicated with clozapine—Implications for pharmacological augmentation strategies in schizophrenia. Pharmacology Research & Perspectives 11 (2). Fulltext not available.

Barda, Christina, Tzoumaka, Alexia, Grafakou, Maria-Eleni, Kalpoutzakis, Eleutherios, Heilmann, Joerg and Skaltsa, Helen (2023) Phytochemical Characterization of Phitosia crocifolia, a Monotypic Representative of Greek Flora. Planta Medica 89 (03), pp. 324-332. Fulltext not available.

Plut, Eva , Calderón, Jacqueline C., Stanojlović, Vesna, Gattor, Albert O., Höring, Carina, Humphrys, Laura J., Konieczny, Adam, Kerres, Sabine, Schubert, Mario , Keller, Max, Cabrele, Chiara, Clark, Timothy and Reiser, Oliver (2023) Stereochemistry-Driven Interactions of α,γ-Peptide Ligands with the Neuropeptide Y Y4-Receptor. Journal of Medicinal Chemistry 66 (14), pp. 9642-9657. Fulltext not available.

Pockes, Steffen , Walters, Michael A. and Ashe, Karen H. (2023) Targeting caspase-2 interactions with tau in Alzheimer's disease and related dementias. Translational Research 254, pp. 34-40. Fulltext not available.

Gleixner, Jakob, Gattor, Albert O., Humphrys, Laura J., Brunner, Thomas and Keller, Max (2023) [3H]UR-JG102–A Radiolabeled Cyclic Peptide with High Affinity and Excellent Selectivity for the Neuropeptide Y Y4 Receptor. Journal of Medicinal Chemistry 66 (19), pp. 13788-13808. Fulltext not available.

Zimmer, Oliver and Goepferich, Achim (2022) How clathrin-coated pits control nanoparticle avidity for cells. Nanoscale Horizons, (Advance Art.).

Sanz-Codina, Maria, Wicha, Sebastian G, Wulkersdorfer, Beatrix, Al Jalali, Valentin, Van Os, Wisse, Vossen, Matthias G, Bauer, Martin, Lackner, Edith, Dorn, Christoph and Zeitlinger, Markus (2022) Comparison of ultrafiltration and microdialysis for ceftriaxone protein-binding determination. Journal of Antimicrobial Chemotherapy. Fulltext not available.

Schindler, Lisa, Moosbauer, Jutta, Schmidt, Daniel , Spruss, Thilo, Grätz, Lukas, Lüdeke, Steffen, Hofheinz, Frank, Meister, Sebastian, Echtenacher, Bernd, Bernhardt, Günther, Pietzsch, Jens , Hellwig, Dirk and Keller, Max (2022) Development of a Neurotensin-Derived 68Ga-Labeled PET Ligand with High In Vivo Stability for Imaging of NTS1 Receptor-Expressing Tumors. Cancers 14 (19), p. 4922.

Forster, Lisa (2022) Development of radioligand binding and functional assays for the characterization of dopamine D2-like receptor ligands. PhD, Universität Regensburg.

Bohley, Marilena (2022) Targeted Lipid Nanoparticles for Retinal Drug Delivery. PhD, Universität Regensburg.

Bohley, Marilena, Dillinger, Andrea E., Schweda, Frank, Ohlmann, Andreas, Braunger, Barbara M., Tamm, Ernst R. and Goepferich, Achim (2022) A single intravenous injection of cyclosporin A–loaded lipid nanocapsules prevents retinopathy of prematurity. Science Advances 8 (38).

Ziegler, Christian, Graf, Moritz, Nagaoka, Makoto and Goepferich, Achim (2022) Investigation of the Impact of Hydrolytically Cleavable Groups on the Stability of Poly(ethylene glycol) Based Hydrogels Cross-Linked via the Inverse Electron Demand Diels-Alder (iEDDA) Reaction. Macromolecular Bioscience 22 (12), p. 2200226.

Heinl, Elena-Sofia, Lorenz, Sebastian, Schmidt, Barbara , Laqtom, Nouf Nasser M., Mazzulli, Joseph R., Francelle, Laetitia , Yu, Timothy W., Greenberg, Benjamin , Storch, Stephan, Tegtmeier, Ines, Othmen, Helga, Maurer, Katja, Steinfurth, Malin, Witzgall, Ralph, Milenkovic, Vladimir M., Wetzel, Christian H. and Reichold, Markus (2022) CLN7/MFSD8 may be an important factor for SARS-CoV-2 cell entry. iScience 25 (10), p. 105082.

Andreev, Stanislav , Plank, Nicole, Schollmeyer, Dieter and Koch, Pierre (2022) (S)-3-(3-((7-Ethynyl-9H-pyrimido[4,5-b]indol-4-yl)amino)piperidin-1-yl)propanenitrile. Molbank 2022 (3), M1437.

Dorn, Christoph , Petroff, David, Kratzer, Alexander, Kees, Frieder, Kloft, Charlotte, Zeitlinger, Markus , Wrigge, Hermann and Simon, Philipp (2022) Tigecycline Soft Tissue Penetration in Obese and Non-obese Surgical Patients Determined by Using In Vivo Microdialysis. European Journal of Drug Metabolism and Pharmacokinetics 47, pp. 749-755.

Meurer, Florian , Dolomanov, Oleg V., Hennig, Christoph , Peyerimhoff, Norbert , Kleemiss, Florian , Puschmann, Horst and Bodensteiner, Michael (2022) Refinement of anomalous dispersion correction parameters in single-crystal structure determinations. IUCrJ / International Union of Crystallography 9 (5), pp. 604-609.

Willkomm, Sarah , Jakob, Leonhard, Kramm, Kevin, Graus, Veronika, Neumeier, Julia, Meister, Gunter and Grohmann, Dina (2022) Single-molecule FRET uncovers hidden conformations and dynamics of human Argonaute 2. Nature Communications 13, art.no.3825.

Schlossmann, Jens (2022) Editorial of the Special Issue: cGMP-Signaling in Cells and Tissues: Molecular, Functional and Pharmacological Aspects. International Journal of Molecular Sciences 23 (12), p. 6482.

Forster, Lisa and Pockes, Steffen (2022) Investigating the ligand agonism and antagonism at the D2long receptor by dynamic mass redistribution. Scientific Reports 12 (1).

Braun, Daniel Simon (2022) Asymmetrisches Dimethylarginin bei psychiatrischen Erkrankungen. PhD, Universität Regensburg.

Bresinsky, Merlin, Strasser, Jessica M., Hubmann, Alexander, Vallaster, Bernadette, McCue, William M., Fuller, Jessica, Singh, Gurpreet, Nelson, Kathryn M., Cuellar, Matthew E., Finzel, Barry C., Ashe, Karen H., Walters, Michael A. and Pockes, Steffen (2022) Characterization of caspase‐2 inhibitors based on specific sites of caspase‐2‐mediated proteolysis. Archiv der Pharmazie 355 (9), p. 2200095.

Majer, Michael (2022) Splenomegalie assoziierte Anämie in Folge der Defizienz des PKGIβ/IRAG1-Signalweges. PhD, Universität Regensburg.

Endres, Katharina Walburga Maria (2022) Wirkstoffkonzentrationsbestimmungen zur Therapieleitung der medikamentösen Behandlung kardiovaskulärer Erkrankungen bei psychiatrischen Patienten. PhD, Universität Regensburg.

Lipecki, Yannick and Haen, Ekkehard (2022) Simultaneous Quantification of 11 Antiseizure Medications and Metabolites in Serum for Therapeutic Drug Monitoring Using High-Performance Liquid Chromatography with Ultraviolet Detection: A Short Communication. Therapeutic Drug Monitoring 44 (2), pp. 345-350. Fulltext not available.

Stahl, Monika, Holzinger, Jonas M., Bülow, Sigrid and Goepferich, Achim (2022) Enzyme-triggered antigen release enhances cross presentation by dendritic cells. Nanomedicine: Nanotechnology, Biology, and Medicine 42, p. 102545. Fulltext not available.

Jorda, Anselm , Wulkersdorfer, Beatrix, Schörgenhofer, Christian, Matzneller, Peter , Al Jalali, Valentin, Bauer, Martin , Wölf-Duchek, Michael, Lackner, Edith, Dorn, Christoph, Jilma, Bernd and Zeitlinger, Markus (2022) Influence of tedizolid on the cytokine response to the endotoxin challenge in healthy volunteers: a cross-over trial. Journal of Antimicrobial Chemotherapy. Fulltext not available.

Konieczny, Adam (2022) Design, Synthesis and Pharmacological Characterization of Oligopeptidic and Non-Peptidic Neuropeptide Y Y4 Receptor Ligands. PhD, Universität Regensburg.

Ousingsawat, Jiraporn , Centeio, Raquel, Cabrita, Inês , Talbi, Khaoula, Zimmer, Oliver , Graf, Moritz, Göpferich, Achim , Schreiber, Rainer and Kunzelmann, Karl (2022) Airway Delivery of Hydrogel-Encapsulated Niclosamide for the Treatment of Inflammatory Airway Disease. International Journal of Molecular Sciences 23 (3), p. 1085.

Rösch, Gundula, Muschter, Dominique, Taheri, Shahed , El Bagdadi, Karima, Dorn, Christoph, Meurer, Andrea, Zaucke, Frank, Schilling, Arndt F., Grässel, Susanne, Straub, Rainer H. and Jenei-Lanzl, Zsuzsa (2022) β2-Adrenoceptor Deficiency Results in Increased Calcified Cartilage Thickness and Subchondral Bone Remodeling in Murine Experimental Osteoarthritis. Frontiers in Immunology 12.

Tahk, Maris-Johanna , Torp, Jane , Ali, Mohammed A. S. , Fishman, Dmytro, Parts, Leopold , Grätz, Lukas , Müller, Christoph , Keller, Max , Veiksina, Santa , Laasfeld, Tõnis and Rinken, Ago (2022) Live-cell microscopy or fluorescence anisotropy with budded baculoviruses—which way to go with measuring ligand binding to M 4 muscarinic receptors? Open Biology 12 (6). Fulltext not available.

Barda, Christina, Anastasiou, Konstantina, Tzara, Ariadni, Grafakou, Maria-Eleni, Kalpoutzakis, Eleftherios, Heilmann, Joerg, Rallis, Michael, Kourounakis, Angeliki P. and Skaltsa, Helen (2022) A Bio-Guided Screening for Antioxidant, Anti-Inflammatory and Hypolipidemic Potential Supported by Non-Targeted Metabolomic Analysis of Crepis spp. Molecules 27 (19), p. 6173. Fulltext not available.

Andreev, Stanislav, Pantsar, Tatu, Tesch, Roberta, Kahlke, Niclas, El-Gokha, Ahmed, Ansideri, Francesco, Grätz, Lukas, Romasco, Jenny, Sita, Giulia, Geibel, Christian , Lämmerhofer, Michael, Tarozzi, Andrea, Knapp, Stefan , Laufer, Stefan A. and Koch, Pierre (2022) Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors. Journal of Medicinal Chemistry 65 (2), pp. 1283-1301. Fulltext not available.

Mandigma, Mark John P. , Žurauskas, Jonas, MacGregor, Callum I., Edwards, Lee J. , Shahin, Ahmed , d'Heureuse, Ludwig, Yip, Philip, Birch, David J. S. , Gruber, Thomas, Heilmann, Jörg, John, Matthew P. and Barham, Joshua P. (2022) An organophotocatalytic late-stage N–CH3oxidation of trialkylamines toN-formamides with O2in continuous flow. Chemical Science 13 (7), pp. 1912-1924. Fulltext not available.

Katsouri, Ilektra Petrina, Vandervelpen, Ebert Vinciane G., Gattor, Albert Owusu, Engelbeen, Sarah, El Sayed, Abdulrahman, Seitaj, Klejdia, Becerra, Eduardo Daniel Morales and Vanderheyden, Patrick M.L. (2022) Complex FFA1 receptor (in)dependent modulation of calcium signaling by free fatty acids. Biochemical Pharmacology 202, p. 115150. Fulltext not available.

Haen, Ekkehard (2022) Dose-Related Reference Range as a Tool in Therapeutic Drug Monitoring. Therapeutic Drug Monitoring 44 (4), pp. 475-493. Fulltext not available.

Schoretsanitis, Georgios, Haen, Ekkehard, Piacentino, Daria, Conca, Andreas, Endres, Katharina, Hiemke, Christoph, Gründer, Gerhard and Paulzen, Michael (2022) Effects of body weight, smoking status, and sex on plasma concentrations of once-monthly paliperidone palmitate. Expert Review of Clinical Pharmacology 15 (2), pp. 243-249. Fulltext not available.

Prüschenk, Sally and Schlossmann, Jens (2022) Function of IRAG2 Is Modulated by NO/cGMP in Murine Platelets. International Journal of Molecular Sciences 23 (12), p. 6695. Fulltext not available.

Beyer, Mandy, Henninger, Sven J., Haehnel, Patricia S., Mustafa, Al-Hassan M. , Gurdal, Ece , Schubert, Bastian, Christmann, Markus, Sellmer, Andreas , Mahboobi, Siavosh, Drube, Sebastian, Sippl, Wolfgang, Kindler, Thomas and Krämer, Oliver H. (2022) Identification of a highly efficient dual type I/II FMS-like tyrosine kinase inhibitor that disrupts the growth of leukemic cells. Cell Chemical Biology 29 (3), 398-411.e4. Fulltext not available.

Schihada, Hannes, Klompstra, Thomas M. , Humphrys, Laura J. , Cervenka, Igor, Dadvar, Shamim , Kolb, Peter , Ruas, Jorge L. and Schulte, Gunnar (2022) Isoforms of GPR35 have distinct extracellular N-termini that allosterically modify receptor-transducer coupling and mediate intracellular pathway bias. Journal of Biological Chemistry 298 (9), p. 102328. Fulltext not available.

Lautenschlager, Florian , Weiss, Manfred, Feuerer, Sigrun and Wodarz, Norbert (2022) Kratom – eine kurze Übersicht für die Schmerzmedizin. Der Schmerz 36 (2), pp. 128-134. Fulltext not available.

Peterhoff, David , Thalhauser, Stefanie, Neckermann, Patrick , Barbey, Clara, Straub, Kristina, Nazet, Julian, Merkl, Rainer, Längst, Gernot, Breunig, Miriam and Wagner, Ralf (2022) Multivalent display of engineered HIV-1 envelope trimers on silica nanoparticles for targeting and in vitro activation of germline VRC01 B cells. European Journal of Pharmaceutics and Biopharmaceutics 181, pp. 88-101. Fulltext not available.

Schindler, Lisa, Wohlfahrt, Katrin, Gluhacevic von Krüchten, Lara, Prante, Olaf, Keller, Max and Maschauer, Simone (2022) Neurotensin analogs by fluoroglycosylation at Nω-carbamoylated arginines for PET imaging of NTS1-positive tumors. Scientific Reports 12 (1). Fulltext not available.

Greinwald, Anja, Hartmann, Martin, Heilmann, Jörg, Heinrich, Michael, Luick, Rainer and Reif, Albert (2022) Soil and Vegetation Drive Sesquiterpene Lactone Content and Profile in Arnica montana L. Flower Heads From Apuseni-Mountains, Romania. Frontiers in Plant Science 13. Fulltext not available.

Szczepańska, Katarzyna, Podlewska, Sabina, Dichiara, Maria, Gentile, Davide, Patamia, Vincenzo, Rosier, Niklas, Mönnich, Denise, Ruiz Cantero, Ma Carmen, Karcz, Tadeusz, Łażewska, Dorota, Siwek, Agata, Pockes, Steffen, Cobos, Enrique J., Marrazzo, Agostino, Stark, Holger, Rescifina, Antonio, Bojarski, Andrzej J., Amata, Emanuele and Kieć-Kononowicz, Katarzyna (2022) Structural and Molecular Insight into Piperazine and Piperidine Derivatives as Histamine H3 and Sigma-1 Receptor Antagonists with Promising Antinociceptive Properties. ACS Chemical Neuroscience 13 (1), pp. 1-15. Fulltext not available.

Müller, Christoph, Gleixner, Jakob , Tahk, Maris-Johanna , Kopanchuk, Sergei , Laasfeld, Tõnis, Weinhart, Michael, Schollmeyer, Dieter, Betschart, Martin U., Lüdeke, Steffen, Koch, Pierre, Rinken, Ago and Keller, Max (2022) Structure-Based Design of High-Affinity Fluorescent Probes for the Neuropeptide Y Y1 Receptor. Journal of Medicinal Chemistry 65 (6), pp. 4832-4853. Fulltext not available.

Rösch, G., El Bagdadi, K., Muschter, D., Taheri, S. , Dorn, C., Meurer, A., Straub, R.H., Zaucke, F. , Schilling, A.F., Grässel, S. and Jenei-Lanzl, Z. (2022) Sympathectomy aggravates subchondral bone changes during osteoarthritis progression in mice without affecting cartilage degeneration or synovial inflammation. Osteoarthritis and Cartilage 30 (3), pp. 461-474. Fulltext not available.

Bohley, Marilena , Dillinger, Andrea E., Tamm, Ernst R. and Goepferich, Achim (2022) Targeted drug delivery to the retinal pigment epithelium: Untapped therapeutic potential for retinal diseases. Drug Discovery Today 27 (9), pp. 2497-2509. Fulltext not available.

Mietzner, Raphael , Pawlak, Ramona , Tamm, Ernst R., Goepferich, Achim , Fuchshofer, Rudolf and Breunig, Miriam (2021) Angiopoietin-1 Mimetic Nanoparticles for Restoring the Function of Endothelial Cells as Potential Therapeutic for Glaucoma. Pharmaceuticals 15 (1), p. 18.

Harloff, Manuela (2021) Der sGC-Aktivator Cinaciguat als Therapieoption der diabetischen Nephropathie und Untersuchung von glukoseinduzierten molekularen Mechanismen in Mesangialzellen. PhD, Universität Regensburg.

Prüschenk, Sally, Majer, Michael , Schreiber, Rainer and Schlossmann, Jens (2021) IRAG2 Interacts with IP3-Receptor Types 1, 2, and 3 and Regulates Intracellular Ca2+ in Murine Pancreatic Acinar Cells. International Journal of Molecular Sciences 22 (24), p. 13409.

Busse, David, Simon, Philipp, Schmitt, Lisa, Petroff, David, Dorn, Christoph , Dietrich, Arne, Zeitlinger, Markus, Huisinga, Wilhelm, Michelet, Robin, Wrigge, Hermann and Kloft, Charlotte (2021) Comparative Plasma and Interstitial Tissue Fluid Pharmacokinetics of Meropenem Demonstrate the Need for Increasing Dose and Infusion Duration in Obese and Non-obese Patients. Clinical Pharmacokinetics.

Dorn, Christoph (2021) 3.3. Informationen über Arzneimittel. In: Sax, Michael, (ed.) Pharmazie für die Praxis : Lehrbuch für Pharmazeuten im Praktikum : Handbuch für die Apotheke. Deutscher Apotheker Verlag, Stuttgart, pp. 152-173. ISBN 978-3-7692-7010-5. Fulltext not available.

Rösch, Gundula, El Bagdadi, Karima, Muschter, Dominique , Taheri, Shahed, Dorn, Christoph , Meurer, Andrea, Straub, Rainer H. , Zaucke, Frank , Schilling, Arndt F., Grässel, Susanne and Jenei-Lanzl, Zsuzsa (2021) Sympathectomy aggravates subchondral bone changes during osteoarthritis progression in mice without affecting cartilage degeneration or synovial inflammation. Osteoarthritis and Cartilage 30 (3), pp. 461-474. Fulltext not available.

Lawrowska, Alexandra (2021) Nanoparticles for drug delivery to ocular neovascularizations. PhD, Universität Regensburg.

Kuck, Katrin (2021) Isolierung von terpenoiden Sekundärstoffen aus C. myrrha und pharmakologische Testung in einem ICAM-1 in vitro Modell. PhD, Universität Regensburg.

Tremmel, Martina, Paetzel, Christian and Heilmann, Jörg (2021) In Vitro Liver Metabolism of Six Flavonoid C-Glycosides. Molecules 26 (21), pp. 1-14.

Wachholz, Vanessa, Mustafa, Al-Hassan M., Zeyn, Yanira, Henninger, Sven J., Beyer, Mandy, Dzulko, Melanie, Piée-Staffa, Andrea, Brachetti, Christina, Haehnel, Patricia S., Sellmer, Andreas, Mahboobi, Siavosh, Kindler, Thomas, Brenner, Walburgis, Nikolova, Teodora and Krämer, Oliver H. (2021) Inhibitors of class I HDACs and of FLT3 combine synergistically against leukemia cells with mutant FLT3. Archives of Toxicology 96 (1), pp. 177-193.

Bartole, Edith (2021) Design, Synthesis and Characterization of Molecular Tools for the Histamine H3 and H4 Receptors – In Particular Radio- and Fluorescent Ligands. PhD, Universität Regensburg.

Busse, David, Borghardt, Jens Markus, Petroff, David, Pevzner, Alice, Dorn, Christoph , El‐Najjar, Nahed, Huisinga, Wilhelm, Wrigge, Hermann, Simon, Philipp and Kloft, Charlotte (2021) EVALUATING PREDICTION METHODS FOR GLOMERULAR FILTRATION TO OPTIMISE DRUG DOSES IN OBESE AND NON‐OBESE PATIENTS. British Journal of Clinical Pharmacology. Fulltext not available.

Höring, Carina , Conrad, Marcus, Söldner, Christian A. , Wang, Jinan , Sticht, Heinrich , Strasser, Andrea and Miao, Yinglong (2021) Specific Engineered G Protein Coupling to Histamine Receptors Revealed from Cellular Assay Experiments and Accelerated Molecular Dynamics Simulations. International Journal of Molecular Sciences 22 (18), pp. 1-21.

Seibel-Ehlert, Ulla , Plank, Nicole, Inoue, Asuka, Bernhardt, Guenther and Strasser, Andrea (2021) Label-Free Investigations on the G Protein Dependent Signaling Pathways of Histamine Receptors. International Journal of Molecular Sciences 22 (18), pp. 1-33.

Busse, David , Simon, Philipp , Petroff, David, Dorn, Christoph, Schmitt, Lisa, Bindellini, Davide, Kratzer, Alexander, Dietrich, Arne, Zeitlinger, Markus, Huisinga, Wilhelm , Michelet, Robin , Wrigge, Hermann and Kloft, Charlotte (2021) Similar Piperacillin/Tazobactam Target Attainment in Obese versus Nonobese Patients despite Differences in Interstitial Tissue Fluid Pharmacokinetics. Pharmaceutics 13 (9), p. 1380.

Heilmann, Jörg, Tremmel, Martina and Kiermaier, Josef (2021) In Vitro Metabolism of Six C-Glycosidic Flavonoids from Passiflora incarnata L. International Journal of Molecular Sciences 2021 (22), p. 6566. (Submitted)

Breunig, Miriam , Sonntag, Tobias, Froemel, Franziska, Stamer, W. Daniel, Ohlmann, Andreas and Fuchshofer, Rudolf (2021) Distribution of Gold Nanoparticles in the Anterior Chamber of the Eye after Intracameral Injection for Glaucoma Therapy. Pharmaceutics 2021 (13), p. 901. (Submitted)

Buschmann, Jonas (2021) Synthesis and pharmacological characterization of argininamide-type neuropeptide Y (NPY) Y1 and Y2 receptor antagonists and synthesis of non-peptide potential NPY Y4 receptor ligands. PhD, Universität Regensburg.

Peterhoff, David , Thalhauser, Stefanie, Sobczak, Jan M., Mohsen, Mona O., Voigt, Christoph, Seifert, Nicole , Neckermann, Patrick, Hauser, Alexandra , Ding, Song, Sattentau, Quentin, Bachmann, Martin F. , Breunig, Miriam and Wagner, Ralf (2021) Augmenting the Immune Response against a Stabilized HIV-1 Clade C Envelope Trimer by Silica Nanoparticle Delivery. Vaccines 9 (642), pp. 1-24.

Maslanka Figueroa, Sara (2021) Heteromultivalent Virus-mimetic Nanoparticles for Specific Mesangial Cell Targeting. PhD, Universität Regensburg.

Schlossmann, Jens, Majer, Michael and Prueschenk, Sally (2021) Loss of PKGIβ/IRAG1 Signaling Causes Anemia-Associated Splenomegaly. International Journal of Molecular Sciences 22 (5458), pp. 1-20.

Pockes, Steffen and Tropmann, Katharina (2021) Histamine H2 receptor radioligands: triumphs and challenges. Future Medicinal Chemistry 13 (12), pp. 1073-1081.

Schießer, Selina, Hitzenbichler, Florian, Kees, Martin Georg, Kratzer, Alexander, Lubnow, Matthias , Salzberger, Bernd , Kees, Frieder and Dorn, Christoph (2021) Measurement of Free Plasma Concentrations of Beta-Lactam Antibiotics. Therapeutic Drug Monitoring 43 (2), pp. 264-270. Fulltext not available.

Göpferich, Achim , Fleischmann, Daniel, Harloff, Manuela, Figueroa, Sara Maslanka and Schlossmann, Jens (2021) Targeted Delivery of Soluble Guanylate Cyclase (sGC) Activator Cinaciguat to Renal Mesangial Cells via Virus-Mimetic Nanoparticles Potentiates Anti-Fibrotic Effects by cGMP-Mediated Suppression of the TGF-β Pathway. International Journal of Molecular Sciences 22 (2557), pp. 1-18. (Submitted)

Weinhart, Corinna G. (2021) Synthesis and pharmacological characterization of
dibenzodiazepinone-type muscarinic M2-receptor
antagonists conjugated to fluorescent dyes or
small peptides. PhD, Universität Regensburg.

Maslanka-Figueroa, Sara , Fleischmann, Daniel and Göpferich, Achim (2021) Biomedical nanoparticle design: What we can learn from viruses. Journal of Controlled Release 329, pp. 552-569. Fulltext not available.

Hoffmeister, Helen, Fuchs, Andreas , Komives, Elizabeth, Groebner‐Ferreira, Regina, Strobl, Laura, Nazet, Julian, Heizinger, Leonhard, Merkl, Rainer, Dove, Stefan and Längst, Gernot (2021) Sequence and functional differences in the ATPase domains of CHD3 and SNF2H promise potential for selective regulability and drugability. The FEBS Journal 288, pp. 4000-4023.

Rosier, Niklas, Grätz, Lukas, Schihada, Hannes , Möller, Jan, Işbilir, Ali , Humphrys, Laura J. , Nagl, Martin, Seibel, Ulla, Lohse, Martin J. and Pockes, Steffen (2021) A Versatile Sub-Nanomolar Fluorescent Ligand Enables NanoBRET Binding Studies and Single-Molecule Microscopy at the Histamine H3 Receptor. Journal of Medicinal Chemistry 64 (15), pp. 11695-11708. Fulltext not available.

Ziegler, Christian, Graf, Moritz, Beck, Sebastian and Göpferich, Achim (2021) A novel anhydrous preparation of PEG hydrogels enables high drug loading with biologics for controlled release applications. European Polymer Journal (147), p. 110286. Fulltext not available.

Tropmann, Katharina, Bresinsky, Merlin, Forster, Lisa, Mönnich, Denise, Buschauer, Armin , Wittmann, Hans-Joachim, Hübner, Harald, Gmeiner, Peter, Pockes, Steffen and Strasser, Andrea (2021) Abolishing Dopamine D2long/D3 Receptor Affinity of Subtype-Selective Carbamoylguanidine-Type Histamine H2 Receptor Agonists. Journal of Medicinal Chemistry 64 (12), pp. 8684-8709. Fulltext not available.

Endres, Katharina, Schiller, Ernst and Haen, Ekkehard (2021) Antihypertensiva in der Psychiatrie. Der Nervenarzt 92, pp. 487-792.

Groner, Jonas, Göpferich, Achim and Breunig, Miriam (2021) Atherosclerosis: Conventional intake of cardiovascular drugs versus delivery using nanotechnology - A new chance for causative therapy? Journal of Controlled Release 333, pp. 539-559. Fulltext not available.

Grätz, Lukas, Laasfeld, Tõnis, Allikalt, Anni , Gruber, Corinna G., Pegoli, Andrea, Tahk, Maris-Johanna, Tsernant, Mari-Liis, Keller, Max and Rinken, Ago (2021) BRET- and fluorescence anisotropy-based assays for real-time monitoring of ligand binding to M2 muscarinic acetylcholine receptors. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1868 (3), p. 118930. Fulltext not available.

Kuzin, Maxim , Haen, Ekkehard, Hiemke, Christoph , Bochon, Benjamin, Bochon, Karolina, Gründer, Gerhard, Paulzen, Michael and Schoretsanitis, Georgios (2021) Body mass index as a determinant of clozapine plasma concentrations: A pharmacokinetic-based hypothesis. Journal of Psychopharmacology 35 (3), pp. 273-278. Fulltext not available.

Grafakou, Maria-Eleni, Barda, Christina, Karikas, George A., Heilmann, Joerg and Skaltsa, Helen (2021) Cajamolides A-N: Cytotoxic and anti-inflammatory sesquiterpene lactones from Calea jamaicensis. Bioorganic Chemistry 116, p. 105351. Fulltext not available.

Gergs, Ulrich, Büxel, Maren L., Bresinsky, Merlin, Kirchhefer, Uwe, Fehse, Charlotte, Höring, Carina, Hofmann, Britt, Marušáková, Margaréta, Čináková, Aneta, Schwarz, Rebecca, Pockes, Steffen and Neumann, Joachim (2021) Cardiac Effects of Novel Histamine H2 Receptor Agonists. Journal of Pharmacology and Experimental Therapeutics 379 (3), pp. 223-234. Fulltext not available.

Stoelzle-Feix, Sonja, Juhasz, Krisztina, Skiba, Michael, Wegener, Joachim, Knox, Ronald, Lemme, Marta, Thomas, Ulrich, Engelstaedter, Max, Dragicevic, Elena, George, Michael and Fertig, Niels (2021) Cell monitoring using multi-frequency impedance recordings for label-free and time-resolved cell response analysis. Journal of Pharmacological and Toxicological Methods 111, p. 106969. Fulltext not available.

Barda, C., Grafakou, M.-E. , Kalpoutzakis, E., Heilmann, J. and Skaltsa, H. (2021) Chemical composition of Crepis foetida L. and C. rubra L. volatile constituents and evaluation of the in vitro anti-inflammatory activity of salicylaldehyde rich volatile fraction. Biochemical Systematics and Ecology 96, p. 104256. Fulltext not available.

Schoretsanitis, Georgios, Haen, Ekkehard, Piacentino, Daria, Conca, Andreas, Endres, Katharina, Hiemke, Christoph, Gründer, Gerhard and Paulzen, Michael (2021) Clinical response in patients treated with once-monthly paliperidone palmitate: analysis of a therapeutic drug monitoring (TDM) database. European Archives of Psychiatry and Clinical Neuroscience 271 (8), pp. 1437-1443. Fulltext not available.

Reynders, Martin, Chaikuad, Apirat, Berger, Benedict‐Tilman, Bauer, Katharina, Koch, Pierre , Laufer, Stefan, Knapp, Stefan and Trauner, Dirk (2021) Controlling the Covalent Reactivity of a Kinase Inhibitor with Light. Angewandte Chemie International Edition 60 (37), pp. 20178-20183. Fulltext not available.

Wörle, Elisabeth, Jakob, Leonhard, Schmidbauer, Andreas, Zinner, Gabriel and Grohmann, Dina (2021) Decoupling the bridge helix of Cas12a results in a reduced trimming activity, increased mismatch sensitivity and impaired conformational transitions. Nucleic Acids Research 49 (9), pp. 5278-5293. Fulltext not available.

Antoni, Frauke and Bernhardt, Günther (2021) Derivatives of nitrogen mustard anticancer agents with improved cytotoxicity. Archiv der Pharmazie 354, e2000366.

Weinhart, Corinna. G., Wifling, David, Schmidt, Maximilian. F., Neu, Eduard, Höring, Carina, Clark, Timothy, Gmeiner, Peter and Keller, Max (2021) Dibenzodiazepinone-type muscarinic receptor antagonists conjugated to basic peptides: Impact of the linker moiety and unnatural amino acids on M2R selectivity. European Journal of Medicinal Chemistry 213, p. 113159. Fulltext not available.

Fleischmann, Daniel and Goepferich, Achim (2021) General sites of nanoparticle biodistribution as a novel opportunity for nanomedicine. European Journal of Pharmaceutics and Biopharmaceutics 166, pp. 44-60. Fulltext not available.

Max, Julianna and Heilmann, Jörg (2021) Homoadamantane and Adamantane Acylphloroglucinols from Hypericum hirsutum. Planta Medica 87 (14), pp. 1167-1183. Fulltext not available.

Ziegler, Christian E., Graf, Moritz, Nagaoka, Makoto, Lehr, Heike and Goepferich, Achim M. (2021) In Situ Forming iEDDA Hydrogels with Tunable Gelation Time Release High-Molecular Weight Proteins in a Controlled Manner over an Extended Time. Biomacromolecules 22 (8), pp. 3223-3236. Fulltext not available.

Grafakou, Maria-Eleni, Barda, Christina, Heilmann, Joerg and Skaltsa, Helen (2021) Macrocyclic Diterpenoid Constituents of Euphorbia deflexa, an Endemic Spurge from Greece. Journal of Natural Products 84 (11), pp. 2893-2903. Fulltext not available.

Gaebler, Arnim Johannes , Schoretsanitis, Georgios, Ben Omar, Nagia, Haen, Ekkehard, Endres, Katharina, Hiemke, Christoph and Paulzen, Michael (2021) Metamizole but not ibuprofen reduces the plasma concentration of sertraline: Implications for the concurrent treatment of pain and depression/anxiety disorders. British Journal of Clinical Pharmacology 87 (3), pp. 1111-1119.

Konieczny, Adam, Conrad, Marcus, Ertl, Fabian J., Gleixner, Jakob, Gattor, Albert O., Grätz, Lukas, Schmidt, Maximilian F., Neu, Eduard, Horn, Anselm H. C., Wifling, David, Gmeiner, Peter, Clark, Timothy, Sticht, Heinrich and Keller, Max (2021) N-Terminus to Arginine Side-Chain Cyclization of Linear Peptidic Neuropeptide Y Y4 Receptor Ligands Results in Picomolar Binding Constants. Journal of Medicinal Chemistry 64 (22), pp. 16746-16769. Fulltext not available.

Dorn, Christoph , Petroff, David, Stoelzel, Melanie, Kees, Martin G. , Kratzer, Alexander, Dietrich, Arne, Kloft, Charlotte, Zeitlinger, Markus, Kees, Frieder , Wrigge, Hermann and Simon, Philipp (2021) Perioperative administration of cefazolin and metronidazole in obese and non-obese patients: a pharmacokinetic study in plasma and interstitial fluid. Journal of Antimicrobial Chemotherapy. Fulltext not available.

Schoretsanitis, Georgios, Haen, Ekkehard, Piacentino, Daria, Conca, Andreas, Endres, Katharina, Carpi, Fabio, Hiemke, Christoph, Gründer, Gerhard and Paulzen, Michael (2021) Pharmacokinetic Correlates of Once-Monthly Paliperidone Palmitate-Related Adverse Drug Reactions. Clinical Pharmacokinetics 60 (12), pp. 1583-1589. Fulltext not available.

Biselli, Sabrina, Bresinsky, Merlin, Tropmann, Katharina, Forster, Lisa , Honisch, Claudia , Buschauer, Armin, Bernhardt, Günther and Pockes, Steffen (2021) Pharmacological characterization of a new series of carbamoylguanidines reveals potent agonism at the H2R and D3R. European Journal of Medicinal Chemistry 214, p. 113190. Fulltext not available.

Al Jalali, V. , Wölfl-Duchek, M., Taubert, M. , Matzneller, P. , Lackner, E., Dorn, Christoph , Kratzer, A., Wulkersdorfer, B., Österreicher, Z and Zeitlinger, Markus (2021) Plasma and soft tissue pharmacokinetics of ceftolozane/tazobactam in healthy volunteers after single and multiple intravenous infusion: a microdialysis study. Journal of Antimicrobial Chemotherapy. Fulltext not available.

Grafakou, Maria-Eleni, Barda, Christina, Pintać, Diandra, Lesjak, Marija, Heilmann, Jörg and Skaltsa, Helen (2021) Prenylated Acylphloroglucinols from Hypericum jovis with Anti-inflammatory Potential. Planta Medica 87 (14), pp. 1184-1191. Fulltext not available.

Ibrahim, Ahmed B. M., Mahmoud, Ghada Abd‐Elmonsef , Meurer, Florian and Bodensteiner, Michael (2021) Preparation and crystallographic studies of a new mercuric salicylaldimine complex for fabrication of microscaled and nanoscaled mercuric sulfide as antimicrobial agents against human pathogenic yeasts and filamentous fungi. Applied Organometallic Chemistry 35 (3). Fulltext not available.

Aldag, Pierre, Welzel, Fabian, Jakob, Leonhard, Schmidbauer, Andreas, Rutkauskas, Marius, Fettes, Fergus, Grohmann, Dina and Seidel, Ralf (2021) Probing the stability of the SpCas9–DNA complex after cleavage. Nucleic Acids Research 49 (21), pp. 12411-12421. Fulltext not available.

Wulkersdorfer, Beatrix, Wicha, Sebastian G., Kurdina, Elizaveta, Carrion Carrera, Stephan F., Matzneller, Peter, Al Jalali, Valentin, Vossen, Matthias G., Riesenhuber, Sonja, Lackner, Edith, Dorn, Christoph and Zeitlinger, Markus (2021) Protein binding of clindamycin in vivo by means of intravascular microdialysis in healthy volunteers. Journal of Antimicrobial Chemotherapy. Fulltext not available.

Daskalaki, Artemis, Grafakou, Maria-Eleni , Barda, Christina, Kypriotakis, Zacharias, Heilmann, Jörg and Skaltsa, Helen (2021) Secondary metabolites from Hypericum trichocaulon Boiss. & Heldr., growing wild in the island of crete. Biochemical Systematics and Ecology 97, p. 104294. Fulltext not available.

Eitel, Michael , Zinad, Dhafer S. , Schollmeyer, Dieter, Gross, Harald and Koch, Pierre (2021) Selective mono-de-O-acetylation of the per-O-acetylated brasilicardin carbohydrate side chain. Carbohydrate Research 504, p. 108312. Fulltext not available.

Tropmann, Katharina, Seibel-Ehlert, Ulla, Littmann, Timo and Strasser, Andrea (2021) Shining light on the histamine H2 receptor: Synthesis of carbamoylguanidine-type agonists as a pharmacological tool to study internalization. Bioorganic & Medicinal Chemistry Letters 52, p. 128388. Fulltext not available.

Szczepańska, Katarzyna , Pockes, Steffen , Podlewska, Sabina, Höring, Carina, Mika, Kamil, Latacz, Gniewomir, Bednarski, Marek, Siwek, Agata , Karcz, Tadeusz, Nagl, Martin, Bresinsky, Merlin, Mönnich, Denise, Seibel, Ulla, Kuder, Kamil J. , Kotańska, Magdalena, Stark, Holger, Elz, Sigurd and Kieć-Kononowicz, Katarzyna (2021) Structural modifications in the distal, regulatory region of histamine H3 receptor antagonists leading to the identification of a potent anti-obesity agent. European Journal of Medicinal Chemistry 213, p. 113041. Fulltext not available.

Eap, C. B. , Gründer, G. , Baumann, P. , Ansermot, N., Conca, A., Corruble, E., Crettol, S., Dahl, M. L., de Leon, J. , Greiner, C., Howes, O., Kim, E., Lanzenberger, R., Meyer, J. H., Moessner, R., Mulder, H., Müller, D. J., Reis, M., Riederer, P., Ruhe, H. G., Spigset, O., Spina, E., Stegman, B., Steimer, W., Stingl, J. , Suzen, S., Uchida, H., Unterecker, S., Vandenberghe, F. and Hiemke, C. (2021) Tools for optimising pharmacotherapy in psychiatry (therapeutic drug monitoring, molecular brain imaging and pharmacogenetic tests): focus on antidepressants. The World Journal of Biological Psychiatry 22 (8), pp. 561-628. Fulltext not available.

Kuck, Katrin, Jürgenliemk, Guido, Lipowicz, Bartosz and Heilmann, Jörg (2020) Sesquiterpenes from Myrrh and Their ICAM-1 Inhibitory Activity In Vitro. Molecules 26 (1), p. 42.

Höring, Carina , Seibel, Ulla , Tropmann, Katharina, Grätz, Lukas , Mönnich, Denise , Pitzl, Sebastian, Bernhardt, Günther , Pockes, Steffen and Strasser, Andrea (2020) A Dynamic, Split-Luciferase-Based Mini-G Protein Sensor to Functionally Characterize Ligands at All Four Histamine Receptor Subtypes. International Journal of Molecular Sciences 21 (22), p. 8440.

Antoni, Frauke , Wifling, David and Bernhardt, Günther (2020) Water-soluble inhibitors of ABCG2 (BCRP) – A fragment-based and computational approach. European Journal of Medicinal Chemistry, p. 112958. Fulltext not available.

Simeth, Nadja Anita , Kinateder, Thomas, Rajendran, Chitra, Nazet, Julian, Merkl, Rainer , Sterner, Reinhard , König, Burkhard and Kneuttinger, Andrea C. (2020) Towards Photochromic Azobenzene‐Based Inhibitors for Tryptophan Synthase. Chemistry—A European Journal 27, pp. 2439-2451.

Bahr, Lisa-Marie (2020) Investigating the role of the central and the peripheral
benzodiazepine receptor on stress and anxiety related
parameters. PhD, Universität Regensburg.

Naporra, Franziska Gertraud (2020) Synthese und pharmakologische Charakterisierung neuer trizyklischer Liganden am Histamin-H1/H4-Rezeptor. PhD, Universität Regensburg.

Grätz, Lukas, Tropmann, Katharina, Bresinsky, Merlin, Müller, Christoph, Bernhardt, Günther and Pockes, Steffen (2020) NanoBRET binding assay for histamine H2 receptor ligands using live recombinant HEK293T cells. Scientific Reports 10, p. 13288.

Schwarz, Mirjam (2020) Erstellung eines Hypotonie-Risikoscores und Validierung anhand einer retrospektiven Anwendungsbeobachtung an geriatrischen Patienten. PhD, Universität Regensburg.

Mietzner, Raphael , Kade, Christian, Froemel, Franziska, Pauly, Diana, Stamer, W. Daniel, Ohlmann, Andreas, Wegener, Joachim, Fuchshofer, Rudolf and Breunig, Miriam (2020) Fasudil Loaded PLGA Microspheres as Potential Intravitreal Depot Formulation for Glaucoma Therapy. Pharmaceutics 12 (8), p. 706.

Habs, Michael and Koller, Michael (2020) Material Risks of Homeopathic Medicinal Products: Regulatory Frameworks, Results of Preclinical Toxicology, and Clinical Meta-Analyses and Their Implications. Complementary Medicine Research 21 (1), pp. 64-84.

Littmann, Timo (2020) Towards a method for the simultaneous quantification of Gαq activation β-arrestin2 recruitment. PhD, Universität Regensburg.

Bartole, Edith, Grätz, Lukas, Littmann, Timo, Wifling, David , Seibel, Ulla, Buschauer, Armin and Bernhardt, Günther (2020) UR-DEBa242: A Py-5-Labeled Fluorescent Multipurpose Probe for Investigations on the Histamine H3 and H4 Receptors. Journal of Medicinal Chemistry 63 (10), pp. 5297-5311. Fulltext not available.

Maslanka Figueroa, Sara , Fleischmann, Daniel, Beck, Sebastian, Tauber, Philipp, Witzgall, Ralph, Schweda, Frank and Goepferich, Achim (2020) Nanoparticles Mimicking Viral Cell Recognition Strategies Are Superior Transporters into Mesangial Cells. Advanced Science 7 (11), p. 1903204.

Guter, Michaela (2020) Layer-by-layer nanoparticles for glaucoma therapy. PhD, Universität Regensburg.

Dorn, Christoph , Schießer, Selina, Wulkersdorfer, Beatrix, Hitzenbichler, Florian, Kees, Martin G. and Zeitlinger, Markus (2020) Determination of free clindamycin, flucloxacillin or tedizolid in plasma: Keep attention to physiological conditions when using ultrafiltration. Biomedical Chromatography 34, e4820.

Goepferich, Achim , Maslanka-Figueroa, Sara, Fleischmann, Daniel and Beck, Sebastian (2020) Thermodynamic, Spatial and Methodological Considerations for the Manufacturing of Therapeutic Polymer Nanoparticles. Pharmaceutical Research 37 (59).

Veser, Anika (2020) Multivalently binding antagonists for the neurokinin-1 receptor. PhD, Universität Regensburg.

Abstiens, Kathrin (2020) Heteromultivalent Nanoparticles for Selective Targeting of Renal Cells. PhD, Universität Regensburg.

Koehler, Katrin, Hmida, Dorra, Schlossmann, Jens, Landgraf, Dana, Reisch, Nicole, Schuelke, Markus and Huebner, Angela (2020) Homozygous mutation in murine retrovirus integration site 1 gene associated with a non‐syndromic form of isolated familial achalasia. Neurogastroenterology & Motility 32 (12). Fulltext not available.

Sellmer, Andreas, Pilsl, Bernadette, Beyer, Mandy, Pongratz, Herwig, Wirth, Lukas, Elz, Sigurd, Dove, Stefan, Henninger, Sven Julian, Spiekermann, Karsten, Polzer, Harald, Klaeger, Susan, Kuster, Bernhard, Böhmer, Frank D., Fiebig, Heinz-Herbert, Krämer, Oliver H. and Mahboobi, Siavosh (2020) A series of novel aryl-methanone derivatives as inhibitors of FMS-like tyrosine kinase 3 (FLT3) in FLT3-ITD-positive acute myeloid leukemia. European Journal of Medicinal Chemistry 193, p. 112232. Fulltext not available.

Fleischmann, Daniel, Maslanka-Figueroa, Sara, Beck, Sebastian, Abstiens, Kathrin, Witzgall, Ralph, Schweda, Frank, Tauber, Philipp and Goepferich, Achim (2020) Adenovirus-Mimetic Nanoparticles: Sequential Ligand-Receptor Interplay as a Universal Tool for Enhanced In Vitro/In Vivo Cell Identification. ACS Applied Materials & Interfaces 12 (31), pp. 34689-34702. Fulltext not available.

Spinnler, Katrin, von Krüchten, Lara, Konieczny, Adam, Schindler, Lisa, Bernhardt, Günther and Keller, Max (2020) An Alkyne-functionalized Arginine for Solid-Phase Synthesis Enabling “Bioorthogonal” Peptide Conjugation. ACS Medicinal Chemistry Letters 11 (3), pp. 334-339. Fulltext not available.

Braun, Daniel , Schlossmann, Jens and Haen, Ekkehard (2020) An innovative, time- and cost-saving method for the quantification of asymmetric dimethylarginine in serum by HPLC without evaporation. Separation Science Plus 3, pp. 571-577.

Braun, Daniel, Schlossmann, Jens and Haen, Ekkehard (2020) An innovative, time‐ and cost‐saving method for the quantification of asymmetric dimethylarginine in serum by high‐performance liquid chromatography without evaporation. Separation Science Plus 3 (11-12), pp. 571-577.

Weber, Laura, Kuck, Katrin, Jürgenliemk, Guido, Heilmann, Jörg, Lipowicz, Bartosz and Vissiennon, Cica (2020) Anti-Inflammatory and Barrier-Stabilising Effects of Myrrh, Coffee Charcoal and Chamomile Flower Extract in a Co-Culture Cell Model of the Intestinal Mucosa. Biomolecules 10 (7), p. 1033. Fulltext not available.

Buschmann, Jonas, Seiler, Theresa, Bernhardt, Günther, Keller, Max and Wifling, David (2020) Argininamide-type neuropeptide Y Y1 receptor antagonists: the nature of Nω-carbamoyl substituents determines Y1R binding mode and affinity. RSC Medicinal Chemistry 11 (2), pp. 274-282. Fulltext not available.

Ullah, Sami, Beer, Ronny, Fuhr, Uwe, Taubert, Max , Zeitlinger, Markus, Kratzer, Alexander, Dorn, Christoph, Arshad, Usman, Kofler, Mario and Helbok, Raimund (2020) Brain Exposure to Piperacillin in Acute Hemorrhagic Stroke Patients Assessed by Cerebral Microdialysis and Population Pharmacokinetics. Neurocritical Care.

Liebchen, Uwe, Dorn, Christoph , Kees, Martin, Schiesser, Selina, Hitzenbichler, Florian, Kees, Frieder and Paal, Michael (2020) Comment on “Meropenem, Cefepime, and Piperacillin Protein Binding in Patient Samples”. Therapeutic Drug Monitoring 42 (6), pp. 909-910. Fulltext not available.

Thalhauser, Stefanie, Peterhoff, David, Wagner, Ralf and Breunig, Miriam (2020) Critical design criteria for engineering a nanoparticulate HIV-1 vaccine. Journal of Controlled Release 317, pp. 322-335. Fulltext not available.

Bohley, Marilena S., Birch, Emily, Baumann, Felix J., Dillinger, Andrea E., Tamm, Ernst R. and Goepferich, Achim M. (2020) Design of dye and superparamagnetic iron oxide nanoparticle loaded lipid nanocapsules with dual detectability in vitro and in vivo. International Journal of Pharmaceutics 585, p. 119433. Fulltext not available.

Schihada, Hannes , Ma, Xiaoyuan, Zabel, Ulrike, Vischer, Henry F., Schulte, Gunnar , Leurs, Rob, Pockes, Steffen and Lohse, Martin J. (2020) Development of a Conformational Histamine H3 Receptor Biosensor for the Synchronous Screening of Agonists and Inverse Agonists. ACS Sensors 5 (6), pp. 1734-1742. Fulltext not available.

Gruber, Corinna G., Pegoli, Andrea, Müller, Christoph, Grätz, Lukas, She, Xueke and Keller, Max (2020) Differently fluorescence-labelled dibenzodiazepinone-type muscarinic acetylcholine receptor ligands with high M2R affinity. RSC Medicinal Chemistry 11 (7), pp. 823-832. Fulltext not available.

Andreev, Stanislav, Pantsar, Tatu , El-Gokha, Ahmed, Ansideri, Francesco, Kudolo, Mark, Anton, Débora Bublitz, Sita, Giulia , Romasco, Jenny, Geibel, Christian, Lämmerhofer, Michael , Goettert, Márcia Ines, Tarozzi, Andrea, Laufer, Stefan A. and Koch, Pierre (2020) Discovery and Evaluation of Enantiopure 9H-pyrimido[4,5-b]indoles as Nanomolar GSK-3β Inhibitors with Improved Metabolic Stability. International Journal of Molecular Sciences 21 (21), p. 7823. Fulltext not available.

Tropmann, Katharina, Höring, Carina , Plank, Nicole and Pockes, Steffen (2020) Discovery of a G Protein-Biased Radioligand for the Histamine H2 Receptor with Reversible Binding Properties. Journal of Medicinal Chemistry 63 (21), pp. 13090-13102. Fulltext not available.

Keller, Max, Mahuroof, Shahani A., Hong Yee, Vivyanne, Carpenter, Jessica, Schindler, Lisa, Littmann, Timo, Pegoli, Andrea, Hübner, Harald, Bernhardt, Günther, Gmeiner, Peter and Holliday, Nicholas D. (2020) Fluorescence Labeling of Neurotensin(8–13) via Arginine Residues Gives Molecular Tools with High Receptor Affinity. ACS Medicinal Chemistry Letters 11 (1), pp. 16-22. Fulltext not available.

Biselli, Sabrina, Alencastre, Inês, Tropmann, Katharina, Erdmann, Daniela, Chen, Mengya, Littmann, Timo, Maia, André F. , Gomez-Lazaro, Maria, Tanaka, Miho, Ozawa, Takeaki, Keller, Max, Lamghari, Meriem, Buschauer, Armin and Bernhardt, Günther (2020) Fluorescent H2 Receptor Squaramide-Type Antagonists: Synthesis, Characterization, and Applications. ACS Medicinal Chemistry Letters 11 (8), pp. 1521-1528. Fulltext not available.

Abdellatif, Ahmed , Hennig, Robert, Pollinger, Klaus, Tawfeek, Hesham and Goepferich, Achim (2020) Fluorescent Nanoparticles Coated with a Somatostatin Analogue Target Blood Monocyte for Efficient Leukaemia Treatment. Pharmaceutical Research 37 (11), p. 2017.

Sommer, Judith, Dorn, Christoph , Gäbele, Erwin, Bataille, Frauke, Freese, Kim, Seitz, Tatjana, Thasler, Wolfgang E., Büttner, Reinhard, Weiskirchen, Ralf , Bosserhoff, Anja and Hellerbrand, Claus (2020) Four-And-A-Half LIM-Domain Protein 2 (FHL2) Deficiency Aggravates Cholestatic Liver Injury. Cells 9 (1), p. 248.

Apaolaza, P.S. , Busch, M., Asin-Prieto, E. , Peynshaert, K. , Rathod, R., Remaut, K., Dünker, N. and Göpferich, A. (2020) Hyaluronic acid coating of gold nanoparticles for intraocular drug delivery: Evaluation of the surface properties and effect on their distribution. Experimental Eye Research 198, p. 108151. Fulltext not available.

Biswas, Siladitta, Kojonazarov, Baktybek, Hadzic, Stefan, Majer, Michael, Bajraktari, Ganimete, Novoyatleva, Tatyana, Ghofrani, Hossein Ardeschir, Grimminger, Friedrich, Seeger, Werner, Weissmann, Norbert, Schlossmann, Jens and Schermuly, Ralph Theo (2020) IRAG1 Deficient Mice Develop PKG1β Dependent Pulmonary Hypertension. Cells 9 (10), p. 2280. Fulltext not available.

Yagati, Ajay Kumar , Behrent, Arne, Beck, Sebastian, Rink, Simone, Goepferich, Achim M., Min, Junhong , Lee, Min-Ho and Baeumner, Antje J. (2020) Laser-induced graphene interdigitated electrodes for label-free or nanolabel-enhanced highly sensitive capacitive aptamer-based biosensors. Biosensors and Bioelectronics 164, p. 112272. Fulltext not available.

Simon, Philipp , Busse, David , Petroff, David , Dorn, Christoph , Ehmann, Lisa, Hochstädt, Sophie, Girrbach, Felix, Dietrich, Arne, Zeitlinger, Markus, Kees, Frieder, Kloft, Charlotte and Wrigge, Hermann (2020) Linezolid Concentrations in Plasma and Subcutaneous Tissue are Reduced in Obese Patients, Resulting in a Higher Risk of Underdosing in Critically Ill Patients: A Controlled Clinical Pharmacokinetic Study. Journal of Clinical Medicine 9 (4), p. 1067.

Simon, Philipp, Petroff, David, Busse, David , Heyne, Jana, Girrbach, Felix, Dietrich, Arne, Kratzer, Alexander Ludwig, Zeitlinger, Markus, Kloft, Charlotte, Kees, Frieder, Wrigge, Hermann and Dorn, Christoph (2020) Meropenem Plasma and Interstitial Soft Tissue Concentrations in Obese and Nonobese Patients—A Controlled Clinical Trial. Antibiotics 9 (12), p. 931.

Pontes de Sousa, Ingrid, Ferreira, Antônio Gilberto , Miller Crotti, Antônio Eduardo, Alves dos Santos, Raquel, Kiermaier, Josef, Kraus, Birgit, Heilmann, Jörg and Jacometti Cardoso Furtado, Niege Araçari (2020) New antifungal ent-labdane diterpenes against Candida glabrata produced by microbial transformation of ent-polyalthic acid. Bioorganic Chemistry 95, p. 103560. Fulltext not available.

Konieczny, Adam, Braun, Diana, Wifling, David , Bernhardt, Günther and Keller, Max (2020) Oligopeptides as Neuropeptide Y Y4 Receptor Ligands: Identification of a High-Affinity Tetrapeptide Agonist and a Hexapeptide Antagonist. Journal of Medicinal Chemistry 63 (15), pp. 8198-8215. Fulltext not available.

Rustler, Karin , Gomila, Alexandre , Maleeva, Galyna, Gorostiza, Pau , Bregestovski, Piotr and König, Burkhard (2020) Optical Control of GABAA Receptors with a Fulgimide‐Based Potentiator. Chemistry - A European Journal 26, pp. 12722-12727.

Rustler, Karin , Nitschke, Philipp, Zahnbrecher, Sophie, Zach, Julia, Crespi, Stefano and König, Burkhard (2020) Photochromic evaluation of 3(5)-arylazo-1H-pyrazoles. The Journal of Organic Chemistry 85, pp. 4079-4088. Fulltext not available.

Piacentino, Daria , Kotzalidis, Georgios D. , Schoretsanitis, Georgios , Paulzen, Michael, Haen, Ekkehard, Cappelletti, Simone, Giupponi, Giancarlo, Grözinger, Michael and Conca, Andreas (2020) Plasma Risperidone-related Measures in Children and Adolescents with Oppositional Defiant/Conduct Disorders. Clinical Psychopharmacology and Neuroscience 18 (1), pp. 41-48. Fulltext not available.

Thalhauser, Stefanie, Peterhoff, David, Wagner, Ralf and Breunig, Miriam (2020) Presentation of HIV-1 Envelope Trimers on the Surface of Silicia Nanoparticles. Journal of Pharmaceutical Sciences 109, pp. 911-921. Fulltext not available.

Busse, David , Simon, Philipp, Michelet, Robin , Ehmann, Lisa, Mehner, Frank, Dorn, Christoph , Kratzer, Alexander, Huisinga, Wilhelm, Wrigge, Hermann , Petroff, David and Kloft, Charlotte (2020) Quantification of microdialysis related variability in humans: Clinical trial design recommendations. European Journal of Pharmaceutical Sciences, p. 105607. Fulltext not available.

She, Xueke, Pegoli, Andrea, Gruber, Corinna G., Wifling, David , Carpenter, Jessica, Hübner, Harald, Chen, Mengya, Wan, Jianfei, Bernhardt, Günther, Gmeiner, Peter , Holliday, Nicholas D. and Keller, Max (2020) Red-Emitting Dibenzodiazepinone Derivatives as Fluorescent Dualsteric Probes for the Muscarinic Acetylcholine M2 Receptor. Journal of Medicinal Chemistry 63 (8), pp. 4133-4154. Fulltext not available.

Ehmann, L., Simon, P., Busse, D., Petroff, D., Dorn, Christoph , Huisinga, W., Dietrich, A., Zeitlinger, M., Wrigge, H. and Kloft, C. (2020) Risk of target non-attainment In obese compared to non-obese patients In Calculated linezolid therapy. Clinical Microbiology and Infection. Fulltext not available.

Thalhauser, Stefanie, Peterhoff, David, Wagner, Ralf and Breunig, Miriam (2020) Silica particles incorporated into PLGA-based in situ-forming implants exploit the dual advantage of sustained release and particulate delivery. European Journal of Pharmaceutics and Biopharmaceutics (156), pp. 1-10. Fulltext not available.

Stolwijk, Judith A., Mildner, Anne-Kathrin, Kade, Christian, Skiba, Michael, Bernhardt, Guenther, Buschauer, Armin, Huebner, Harald, Gmeiner, Peter and Wegener, Joachim (2020) Stepwise Dosing Protocol for Increased Throughput in Label-Free Impedance-Based GPCR Assays. Journal of Visualized Experiments (156). Fulltext not available.

Fleischmann, Daniel, Maslanka-Figueroa, Sara and Göpferich, Achim (2020) Steric Shielding of cRGD-Functionalized Nanoparticles from Premature Exposition to Off-Target Endothelial Cells under a Physiological Flow. ACS Applied Bio Materials 4 (1), pp. 640-650. Fulltext not available.

Gienger, Marie, Hübner, Harald, Löber, Stefan, König, Burkhard and Gmeiner, Peter (2020) Structure-based development of caged dopamine D2/D3 receptor antagonists. Scientific Reports, p. 829.

Antoni, Frauke, Bause, Manuel, Scholler, Matthias, Bauer, Stefanie, Stark, Simone Alexandra, Jackson, Scott M., Manolaridis, Ioannis, Locher, Kaspar P., König, Burkhard , Buschauer, Armin and Bernhardt, Günther (2020) Tariquidar-related triazoles as potent, selective and stable inhibitors of ABCG2 (BCRP). European Journal of Medicinal Chemistry 191. Fulltext not available.

Maslanka-Figueroa, Sara , Fleischmann, Daniel, Beck, Sebastian and Goepferich, Achim (2020) The Effect of Ligand Mobility on the Cellular Interaction of Multivalent Nanoparticles. Macromolecular Bioscience 20, p. 900427.

Kuzin, Maxim , Schoretsanitis, Georgios , Haen, Ekkehard, Dammann, Gerhard, Hiemke, Christoph, Gründer, Gerhard and Paulzen, Michael (2020) The Effects of Co-prescription of Pantoprazole on the Clozapine Metabolism. Pharmacopsychiatry 53 (02), pp. 65-70. Fulltext not available.

Maschauer, Simone, Ott, Julian J. , Bernhardt, Günther, Kuwert, Torsten, Keller, Max and Prante, Olaf (2019) 18F-labelled triazolyl-linked argininamides targeting the neuropeptide Y Y1R for PET Imaging of mammary carcinoma. Scientific Reports 9, p. 12990.

Schramm, Andrea, Schweda, Frank, Sequeira-Lopez, Maria Luisa S., Hofmann, Franz, Sandner, Peter and Schlossmann, Jens (2019) Protein Kinase G Is Involved in Acute but Not in Long-Term Regulation of Renin Secretion. Frontiers in Pharmacology 2019 (10), p. 800.

Dorn, Christoph, Petroff, David, Neumann, Nancy, Kratzer, Alexander, El-Najjar, Nahed , Dietrich, Arne, Kloft, Charlotte, Zeitlinger, Markus , Kees, Martin, Kees, Frieder, Wrigge, Hermann and Simon, Philipp (2019) Plasma and tissue pharmacokinetics of fosfomycin in morbidly obese and non-obese surgical patients: a controlled clinical trial. Journal of Antimicrobial Chemotherapy. Fulltext not available.

Pegoli, Andrea, Wifling, David , Gruber, Corinna G., Xueke, She, Hübner, Harald, Bernhardt, Günther, Gmeiner, Peter and Keller, Max (2019) Conjugation of Short Peptides to Dibenzodiazepinone-Type
Muscarinic Acetylcholine Receptor Ligands Determines M2R
Selectivity. Journal of Medicinal Chemistry 62, pp. 5358-5369. Fulltext not available.

Schindler, Lisa, Bernhardt, Günther and Keller, Max (2019) Modifications at Arg and Ile Give Neurotensin(8−13) Derivatives with High Stability and Retained NTS1 Receptor Affinity. ACS Medicinal Chemistry Letters 10 (6), pp. 960-965. Fulltext not available.

Kratzer, Alexander, Rothe, Ulrich, Kees, Frieder and Dorn, Christoph (2019) Stabilität von Ceftolozan/Tazobactam in Infusionslösungen für die verlängerte oder kontinuierliche Applikation. Krankenhauspharmazie 40 (4), pp. 195-200. Fulltext not available.

Pockes, Steffen, Wifling, David , Buschauer, Armin and Elz, Sigurd (2019) Structure‐Activity Relationship of Hetarylpropylguanidines Aiming at the Development of Selective Histamine Receptor Ligands †. ChemistryOpen 8 (3), pp. 285-297.

Rustler, Karin , Pockes, Steffen and König, Burkhard (2019) Light-Switchable Antagonists for the Histamine H1 Receptor at the Isolated Guinea Pig Ileum. ChemMedChem 14 (6), pp. 636-644. Fulltext not available.

Schramm, Simon, Agnetta, Luca, Bermudez, Marcel, Gerwe, Hubert, Irmen, Matthias, Holze, Janine, Littmann, Timo, Wolber, Gerhard , Tränkle, Christian and Decker, Michael (2019) Novel BQCA‐ and TBPB‐Derived M 1 Receptor Hybrid Ligands: Orthosteric Carbachol Differentially Regulates Partial Agonism. ChemMedChem 14 (14), pp. 1349-1358. Fulltext not available.

Maleeva, Galyna , Wutz, Daniel, Rustler, Karin , Nin-Hill, Alba, Alfonso-Prieto, Mercedes , Petukhova, Elena , Bautista-Barrufet, Antoni, Gomila-Juaneda, Alexandre, Scholze, Petra , Peiretti, Franck, Rovira, Carme , König, Burkhard , Gorostiza, Pau and Bregestovski, Piotr (2019) A photoswitchable GABA receptor channel blocker. British Journal of Pharmacology 176, pp. 2661-2677. Fulltext not available.

Dechant, Franz-Xaver, Dechant, Rebecca, Kandulski, Arne, Selgrad, Michael, Weber, Florian, Reischl, Udo, Wilczek, Wolf, Mueller, Martina and Weigand, Kilian (2019) Accuracy of Different Rapid Urease Tests in Comparison with Histopathology in Patients with Endoscopic Signs of Gastritis. Digestion 101 (2), pp. 184-190. Fulltext not available.

Łażewska, Dorota , Mogilski, Szczepan, Hagenow, Stefanie , Kuder, Kamil, Głuch-Lutwin, Monika , Siwek, Agata , Więcek, Małgorzata, Kaleta, Maria, Seibel, Ulla, Buschauer, Armin, Filipek, Barbara, Stark, Holger and Kieć-Kononowicz, Katarzyna (2019) Alkyl derivatives of 1,3,5-triazine as histamine H4 receptor ligands. Bioorganic & Medicinal Chemistry 27 (7), pp. 1254-1262. Fulltext not available.

Polykandriotis, Elias, Horch, Raymund E., Jost, Matthias, Arkudas, Andreas, Kees, Frieder and Schmitz, Marweh (2019) Can systemically administered antibiotics be detected in wound tissues and surfaces under negative pressure wound therapy? International Wound Journal 16 (2), pp. 503-510. Fulltext not available.

Rustler, Karin , Pockes, Steffen and König, Burkhard (2019) Cover Feature: Light‐Switchable Antagonists for the Histamine H 1 Receptor at the Isolated Guinea Pig Ileum (ChemMedChem 6/2019). ChemMedChem 14 (6), p. 614. Fulltext not available.

Kowalewski, Christoph, Haen, Ekkehard, Hiemke, Christoph, Ridders, Florian, Endres, Katharina, Gründer, Gerhard, Paulzen, Michael and Schoretsanitis, Georgios (2019) Cytochrome P450-mediated inhibition of venlafaxine metabolism by trimipramine. International Clinical Psychopharmacology 34 (5), pp. 241-246. Fulltext not available.

Dorn, Christoph , Kratzer, Alexander Ludwig, Schießer, Selina, Kees, Frieder , Wrigge, Hermann and Simon, Philipp (2019) Determination of total or free cefazolin and metronidazole in human plasma or interstitial fluid by HPLC-UV for pharmacokinetic studies in man. Journal of Chromatography B. Fulltext not available.

Veselinović, Tanja, Scharpenberg, Martin, Heinze, Martin, Cordes, Joachim, Mühlbauer, Bernd, Juckel, Georg, Rüther, Eckart, Paulzen, Michael, Haen, Ekkehard, Hiemke, Christoph, Timm, Jürgen, Gründer, Gerhard, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference , make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference and make_name_string expected hash reference (2019) Dopamine D2 Receptor Occupancy Estimated From Plasma Concentrations of Four Different Antipsychotics and the Subjective Experience of Physical and Mental Well-Being in Schizophrenia. Journal of Clinical Psychopharmacology 39 (6), pp. 550-560. Fulltext not available.

Agnetta, Luca, Bermudez, Marcel , Riefolo, Fabio , Matera, Carlo , Claro, Enrique , Messerer, Regina, Littmann, Timo, Wolber, Gerhard , Holzgrabe, Ulrike and Decker, Michael (2019) Fluorination of Photoswitchable Muscarinic Agonists Tunes Receptor Pharmacology and Photochromic Properties. Journal of Medicinal Chemistry 62 (6), pp. 3009-3020. Fulltext not available.

Abstiens, Kathrin , Fleischmann, Daniel, Gregoritza, Manuel and Göpferich, Achim (2019) Gold-Tagged Polymeric Nanoparticles with Spatially Controlled Composition for Enhanced Detectability in Biological Environments. ACS Applied Nano Materials 2 (2), pp. 917-926. Fulltext not available.

Crespi, Stefano , Simeth, Nadja Anita and König, Burkhard (2019) Heteroaryl azo dyes as molecular photoswitches. Nature Reviews Chemistry 3, pp. 133-146. Fulltext not available.

Graf, Moritz, Ziegler, Christian, Gregoritza, Manuel and Goepferich, Achim (2019) Hydrogel microspheres evading alveolar macrophages for sustained pulmonary protein delivery. nternational Journal of Pharmaceutics 566, pp. 652-661. Fulltext not available.

Scharrenbroich, Jessica, Kaever, Volkhard, Dove, Stefan, Seifert, Roland and Schneider, Erich H. (2019) Hydrolysis of the non-canonical cyclic nucleotide cUMP by PDE9A: kinetics and binding mode. Naunyn-Schmiedeberg's Archives of Pharmacology 392 (2), pp. 199-208. Fulltext not available.

Stolwijk, J. A., Skiba, M., Kade, C., Bernhardt, G., Buschauer, Armin , Hübner, H., Gmeiner, P. and Wegener, Joachim (2019) Increasing the throughput of label-free cell assays to study the activation of G-protein-coupled receptors by using a serial agonist exposure protocol. Integrative Biology 11 (3), pp. 99-108. Fulltext not available.

Maslanka-Figueroa, Sara, Veser, Anika, Abstiens, Kathrin, Fleischmann, Daniel and Göpferich, Achim (2019) Influenza A virus mimetic nanoparticles trigger selective cell uptake. PNAS 116 (20), pp. 9831-9836. Fulltext not available.

Gergs, U. , Bernhardt, Günther, Buchwalow, I. B., Edler, H., Fröba, J., Keller, Max, Kirchhefer, U., Köhler, F., Mißlinger, N., Wache, H. and Neumann, J. (2019) Initial Characterization of Transgenic Mice Overexpressing Human Histamine H2 Receptors. Journal of Pharmacology and Experimental Therapeutics 369 (1), pp. 129-141. Fulltext not available.

Bohley, Marilena, Haunberger, Alexandra and Göpferich, Achim (2019) Intracellular availability of poorly soluble drugs from lipid nanocapsules. European Journal of Pharmaceutics and Biopharmaceutics 139, pp. 23-32. Fulltext not available.

Nussbaumer-Pröll, Alina Karoline, Eberl, Sabine, Reiter, Birgit, Stimpfl, Thomas, Dorn, Christoph and Zeitlinger, Markus (2019) Low pH reduces the activity of ceftolozane/tazobactam in human urine, but confirms current breakpoints for urinary tract infections. Journal of Antimicrobial Chemotherapy. Fulltext not available.

Simon, P., Petroff, D., Dorn, Christoph , Ehmann, L., Kloft, C., Prettin, C., Dietrich, A., Zeitlinger, M., Kees, F. and Wrigge, H. (2019) Measurement of soft tissue drug concentrations in morbidly obese and non-obese patients – A prospective, parallel group, open-labeled, controlled, phase IV, single center clinical trial. Contemporary Clinical Trials Communications 15, p. 100375. Fulltext not available.

Abstiens, Kathrin and Göpferich, Achim (2019) Microfluidic manufacturing improves polydispersity of multicomponent polymeric nanoparticles. Journal of Drug Delivery Science and Technology 49, pp. 433-439. Fulltext not available.

Wimmer, Alexander and König, Burkhard (2019) N‑Arylation of NH-Sulfoximines via Dual Nickel Photocatalysis. Organic Letters 21, pp. 2740-2744.

Schoretsanitis, Georgios , Haen, Ekkehard, Hiemke, Christoph, Endres, Katharina, Ridders, Florian, Veselinovic, Tanja, Gründer, Gerhard and Paulzen, Michael (2019) Pharmacokinetic correlates of venlafaxine: associated adverse reactions. European Archives of Psychiatry and Clinical Neuroscience 269 (7), pp. 851-857. Fulltext not available.

Lachmann, Daniel, Konieczny, Adam, Keller, Max and König, Burkhard (2019) Photochromic peptidic NPY Y4-receptor ligands. Organic & Biomolecular Chemistry 17, pp. 2467-2478. Fulltext not available.

Heider, Fabian , Pantsar, Tatu, Kudolo, Mark, Ansideri, Francesco, De Simone, Angela, Pruccoli, Letizia, Schneider, Taiane, Goettert, Marcia Ines, Tarozzi, Andrea, Andrisano, Vincenza, Laufer, Stefan A. and Koch, Pierre (2019) Pyridinylimidazoles as GSK3β Inhibitors: The Impact of Tautomerism on Compound Activity via Water Networks. ACS Medicinal Chemistry Letters 10 (10), pp. 1407-1414. Fulltext not available.

Heider, Fabian , Ansideri, Francesco, Tesch, Roberta, Pantsar, Tatu, Haun, Urs, Döring, Eva, Kudolo, Mark, Poso, Antti , Albrecht, Wolfgang, Laufer, Stefan A. and Koch, Pierre (2019) Pyridinylimidazoles as dual glycogen synthase kinase 3β/p38α mitogen-activated protein kinase inhibitors. European Journal of Medicinal Chemistry 175, pp. 309-329. Fulltext not available.

Nowak, Hartmuth, Weidemann, Caroline, Martini, Stefan, Oesterreicher, Zoe Anne, Dorn, Christoph, Adamzik, Michael, Kees, Frieder, Zeitlinger, Markus and Rahmel, Tim (2019) Repeated determination of moxifloxacin concentrations in interstitial space fluid of muscle and subcutis in septic patients. Journal of Antimicrobial Chemotherapy. Fulltext not available.

Schwindl, Sebastian, Kraus, Birgit and Heilmann, Jörg (2019) Secondary metabolites from the leaves of Juglans regia L. Biochemical Systematics and Ecology 83, pp. 130-136. Fulltext not available.

Soliman, Beatrice, Wang, Ning, Zagotto, Giuseppe and Pockes, Steffen (2019) Synthesis and biological evaluation of heteroalicyclic cyanoguanidines at histamine receptors. Archiv der Pharmazie 352 (9), p. 1900107. Fulltext not available.

Abstiens, Kathrin , Gregoritza, Manuel and Goepferich, Achim (2018) Ligand Density and Linker Length are Critical Factors for Multivalent Nanoparticle−Receptor Interactions. ACS Applied Materials & Interfaces 11 (1), pp. 1311-1320. Fulltext not available.

Makule, Edna E., Kraus, Birgit, Jürgenliemk, Guido, Heilmann, Jörg and Wiesneth, Stefan (2018) Dioic acid glycosides, tannins and methylated ellagic acid glycosides from Morella salicifolia bark. Phytochemistry Letters 28, pp. 76-83. Fulltext not available.

Gregoritza, Manuel (2018) Click Hydrogels for Controlled Local Antibody Delivery. PhD, Universität Regensburg.

Littmann, Timo, Ozawa, Takeaki, Hoffmann, Carsten, Buschauer, Armin and Bernhardt, Günther (2018) A split luciferase-based probe for quantitative proximal determination of Gαq signalling in live cells. Scientific Reports 8 (17179), pp. 1-10.

Kratzer, Alexander, Schießer, Selina, Matzneller, Peter, Wulkersdorfer, Beatrix, Zeitlinger, Markus , Schlossmann, Jens , Kees, Frieder and Dorn, Christoph (2018) Determination of Total and Free Ceftolozane and Tazobactam in Human Plasma and Interstitial Fluid by HPLC-UV. Journal of Pharmaceutical and Biomedical Analysis. Fulltext not available.

Köhler, Julia (2018) Hydrogel Wound Dressings for the Bioactive Treatment of Acute and Chronic Wounds. PhD, Universität Regensburg.

Walz, Johanna Madeleine (2018) VEGF-Inhibition bei der Frühgeborenenretinopathie
- Präklinische und klinische Aspekte -. PhD, Universität Regensburg.

Keil, Stefanie-Klara (2018) Evaluation der massenspektrometrischen Analyse von Serumgallensäuren in der Differentialdiagnostik (cholestatischer) Lebererkrankungen im Kindes- und Jugendalter und zum therapeutischen Drug Monitoring
der Behandlung mit Ursodeoxycholsäure. PhD, Universität Regensburg.

Böhr, Sebastian (2018) Therapeutisches Drug Monitoring der direkten oralen Antikoagulanzien. PhD, Universität Regensburg.

Yang, Zhenlin, Han, Shuo, Keller, Max, Kaiser, Anette, Bender, Brain J., Bosse, Mathias, Burkert, Kerstin, Kögler, Lisa M., Wifling, David , Bernhardt, Günther, Plank, Nicole, Littmann, Timo, Schmidt, Peter, Yi, Cuiying, Li, Beibei, Ye, Sheng, Zhang, Rongguang, Xu, Bo, Larhammar, Dan, Stevens, Raymond C. , Huster, Daniel, Meiler, Jens, Zhao, Qiang, Beck-Sickinger, Annette G., Buschauer, Armin and Wu, Beili (2018) Structural basis of ligand binding modes at the
neuropeptide Y Y1 receptor. Nature 556, pp. 520-524. Fulltext not available.

Schramm, Andrea, Mueller-Thuemen, Philip, Littmann, Timo, Harloff, Manuela, Ozawa, Takeaki and Schlossmann, Jens (2018) Establishing a Split Luciferase Assay for Proteinkinase G (PKG) Interaction Studies. International Journal o f Molecular Sciences 19 (4), p. 1180.

Mayer, Larissa Joyce (2018) Effekte einer konsekutiven Aktivierung des MAP-Kinase-Signalwegs in humanen Melanozyten. PhD, Universität Regensburg.

Pockes, Steffen , Wifling, David , Keller, Max, Buschauer, Armin and Elz, Sigurd (2018) Highly Potent, Stable, and Selective Dimeric Hetarylpropylguanidine-Type Histamine H2 Receptor Agonists. ACS Omega 2018 (3), pp. 2865-2882.

Makule, Edna (2018) Ethnopharmacological survey and phytochemical investigation of Maasai traditional medicinal plants from north-eastern Tanzania. PhD, Universität Regensburg.

Volkov, Ilya B. (2018) Phytochemical and pharmacological study
of Hypericum triquetrifolium TURRA. PhD, Universität Regensburg.

Pockes, Steffen (2018) Synthese und pharmakologische Charakterisierung von Heteroarylpropylguanidin-Derivaten an Histamin-Rezeptorsubtypen: Struktur-Wirkungsbeziehungen mono- und bivalenter Liganden. PhD, Universität Regensburg.

Dietrich, Peter, Kuphal, Silke, Spruss, Thilo, Hellerbrand, Claus and Bosserhoff, Anja K. (2018) Micro RNA ‐622 is a novel mediator of tumorigenicity in melanoma by targeting Kirsten rat sarcoma. Pigment Cell & Melanoma Research 31 (5), pp. 614-629. Fulltext not available.

Littmann, Timo, Ozawa, Takeaki, Hoffmann, Carsten, Buschauer, Armin and Bernhardt, Günther (2018) A split luciferase-based probe for quantitative proximal determination of Gαq signalling in live cells. Scientific Reports 8 (1), p. 17179.

Walz, J. M., Bemme, S., Reichl, S., Akman, S., Breuß, H., Süsskind, D., Glitz, B., Müller, V. C., Wagenfeld, L., Gabel-Pfisterer, A., Aisenbrey, S., Engelmann, K., Koutsonas, A., Krohne, T. U. and Stahl, A. (2018) Behandelte Frühgeborenenretinopathie in Deutschland. Der Ophthalmologe 115 (6), pp. 476-488. Fulltext not available.

Schmidberger, Andreas, Schupfner, Robert and Matysik, Frank-Michael (2018) Development of an analytical strategy for the determination of 228Th and 232Th in ivory based on the combined use of ICP-MS and α-spectrometry. Journal of Radioanalytical and Nuclear Chemistry 318 (3), pp. 2007-2011. Fulltext not available.

Koehler, Julia, Brandl, Ferdinand and Goepferich, Achim (2018) Hydrogel wound dressing for bioactive treatment of acute and chronic wounds. European Polymer Journal 100, pp. 1-11. Fulltext not available.

Dorn, Christoph, Kratzer, Alexander, Liebchen, Uwe, Schleibinger, Michael, Murschhauser, Alexandra, Schlossmann, Jens , Kees, Frieder, Simon, Philipp and Kees, Martin G. (2018) Impact of Experimental Variables on the Protein Binding of Tigecycline in Human Plasma as Determined by Ultrafiltration. Journal of Pharmaceutical Sciences 107 (2), pp. 739-744. Fulltext not available.

Dillinger, Andrea E., Guter, Michaela, Froemel, Franziska, Weber, Gregor R., Perkumas, Kristin, Stamer, W. Daniel, Ohlmann, Andreas, Fuchshofer, Rudolf and Breunig, Miriam (2018) Intracameral Delivery of Layer‐by‐Layer Coated siRNA Nanoparticles for Glaucoma Therapy. Small 14 (50), p. 1803239. Fulltext not available.

Wiesneth, Stefan, Aas, Gregor, Heilmann, Jörg and Jürgenliemk, Guido (2018) Investigation of the flavan-3-ol patterns in willow species during one growing-season. Phytochemistry 145, pp. 26-39. Fulltext not available.

Thamm, M. , Sturm, K., Schlossmann, J. and Scheiner, R. (2018) Levels and activity of cyclic guanosine monophosphate-dependent protein kinase in nurse and forager honeybees. Insect Molecular Biology 27 (6), pp. 815-823. Fulltext not available.

Sellmer, Andreas, Stangl, Hubert, Beyer, Mandy, Grünstein, Elisabeth, Leonhardt, Michel, Pongratz, Herwig, Eichhorn, Emerich, Elz, Sigurd, Striegl, Birgit, Jenei-Lanzl, Zsuzsa, Dove, Stefan, Straub, Rainer H., Krämer, Oliver H. and Mahboobi, Siavosh (2018) Marbostat-100 Defines a New Class of Potent and Selective Antiinflammatory and Antirheumatic Histone Deacetylase 6 Inhibitors. Journal of Medicinal Chemistry 61 (8), pp. 3454-3477. Fulltext not available.

Chuskit, Deachen, Chaudhary, Renu, Venugopalan, Paloth, König, Burkhard and Natarajan, Palani (2018) Oxidative homodimerization of substituted olefins by DDQ visible light photocatalysis. Organic Chemistry Frontiers 5, pp. 3553-3556. Fulltext not available.

Schoretsanitis, Georgios, de Leon, Jose, Haen, Ekkehard, Stegmann, Benedikt, Hiemke, Christoph, Gründer, Gerhard and Paulzen, Michael (2018) Pharmacokinetics of risperidone in different application forms – Comparing long-acting injectable and oral formulations. European Neuropsychopharmacology 28 (1), pp. 130-137. Fulltext not available.

Mathioudaki, Angeliki, Berzesta, Ariola, Kypriotakis, Zacharias, Skaltsa, Helen and Heilmann, Jörg (2018) Phenolic metabolites from Hypericum kelleri Bald., an endemic species of Crete (Greece). Phytochemistry 146, pp. 1-7. Fulltext not available.

Paolillo, Michael , Peters, Stefanie, Schramm, Andrea, Schlossmann, Jens and Feil, Robert (2018) Real-Time Imaging Reveals Augmentation of Glutamate-Induced Ca2+ Transients by the NO-cGMP Pathway in Cerebellar Granule Neurons. International Journal of Molecular Sciences 19, p. 2185.

Jackson, Scott M., Manolaridis, Ioannis, Kowal, Julia , Zechner, Melanie, Taylor, Nicholas M. I. , Bause, Manuel, Bauer, Stefanie, Bartholomaeus, Ruben, Bernhardt, Günther, König, Burkhard , Buschauer, Armin, Stahlberg, Henning , Altmann, Karl-Heinz and Locher, Kaspar P. (2018) Structural basis of small-molecule inhibition of human multidrug transporter ABCG2. Nature Structural & Molecular Biology 25 (4), pp. 333-340. Fulltext not available.

Dolles, Dominik, Hoffmann, Matthias, Gunesch, Sandra, Marinelli, Oliviero, Möller, Jan , Santoni, Giorgio, Chatonnet, Arnaud, Lohse, Martin J. , Wittmann, Hans-Joachim, Strasser, Andrea, Nabissi, Massimo, Maurice, Tangui and Decker, Michael (2018) Structure–Activity Relationships and Computational Investigations into the Development of Potent and Balanced Dual-Acting Butyrylcholinesterase Inhibitors and Human Cannabinoid Receptor 2 Ligands with Pro-Cognitive in Vivo Profiles. Journal of Medicinal Chemistry 61 (4), pp. 1646-1663. Fulltext not available.

Plokhikh, I. V. , Charkin, D. O., Verchenko, V. Yu., Kuznetsov, A. N., Tsirlin, A. A., Kazakov, S. M. and Shevelkov, A. V. (2018) Synthesis, crystal structure and physical properties of europium – manganese fluoride pnictides, EuMnPnF (Pn = P, As, Sb). Journal of Solid State Chemistry 258, pp. 682-690. Fulltext not available.

Peña-Solórzano, Diana, Scholler, Matthias, Bernhardt, Günther, Buschauer, Armin , König, Burkhard and Ochoa-Puentes, Cristian (2018) Tariquidar-Related Chalcones and Ketones as ABCG2 Modulators. ACS Medicinal Chemistry Letters 9, pp. 854-859. Fulltext not available.

Uchida, Hitoshi, Matsumura, Shinji, Katano, Tayo, Watanabe, Masahiko , Schlossmann, Jens and Ito, Seiji (2018) Two isoforms of cyclic GMP-dependent kinase-I exhibit distinct expression patterns in the adult mouse dorsal root ganglion. Molecular Pain 14, p. 174480691879640. Fulltext not available.

Brosig, Andreas Michael (2017) Technical comparison of four different extracorporeal photopheresis systems. PhD, Universität Regensburg.

Chen, Kang, Berg, Nele, Gschwind, Ruth Maria and König, Burkhard (2017) Selective Single C(sp3)−F Bond Cleavage in Trifluoromethylarenes: Merging Visible-Light Catalysis with Lewis Acid Activation. Journal of the American Chemical Society 139, pp. 18444-18447. Fulltext not available.

She, Xueke, Pegoli, Andrea, Mayr, Judith, Hübner, Harald, Bernhardt, Günther , Gmeiner, Peter and Keller, Max (2017) Heterodimerization of Dibenzodiazepinone-Type Muscarinic Acetylcholine Receptor Ligands Leads to Increased M2R Affinity and Selectivity. ACS Omega 2 (10), pp. 6741-6754.

Kuhn, Kilian (2017) Molecular Tools for the NPY Y₄ Receptor Derived from the C-Terminus of hPP and from Argininamide-type Y₁R Antagonists. PhD, Universität Regensburg.

Oswald, Mira (2017) Targeted CNS Delivery via Nanoparticulate Drug Delivery Systems. PhD, Universität Regensburg.

Wetzl, Veronika (2017) Fibrose-assoziierte Biomarker – Einfluss der Behandlung mit Serelaxin im murinen Nierenfibrose-Modell und prädiktiver Aussagewert in der pulmonalen Hypertonie. PhD, Universität Regensburg.

Scheck, Luisa (2017) Characterization of TSPO 18 kDa in neurosteroid synthesis and mitochondrial metabolism. PhD, Universität Regensburg.

Endres, Wolfgang (2017) Reparier Dich Selbst! Working Paper. (Submitted)

Hammer, Nadine (2017) Hydrogels for the Controlled Release of Protein Pharmaceuticals. PhD, Universität Regensburg.

Strasser, Andrea, Wittmann, Hans-Joachim and Seifert, Roland (2017) Binding kinetics and pathways of ligands to GPCRs. Trends in Pharmacological Sciences. (In Press) Fulltext not available.

Dessauer, Carmen W., Watts, Val J., Ostrom, Rennolds S., Conti, Marco, Dove, Stefan and Seifert, Roland (2017) International Union of Basic and Clinical Pharmacology. CI. Structures and Small Molecule Modulators of Mammalian Adenylyl Cyclases. Pharmacological Reviews 69 (2), pp. 93-139. Fulltext not available.

Wiesneth, Stefan, Aas, Gregor, Heilmann, Jörg and Jürgenliemk, Guido (2017) Comparative investigation of the flavan-3-ol patterns in two willows during one growing season. In: International PhD students/Postdocs meeting of the German Pharmaceutical Society (DPhG), 29.-31. März 2017, Frankfurt am Main, Germany. Fulltext not available.

Schlossmann, Jens, Schinner, Elisabeth, Wetzl, Veronika, Schramm, Andrea, Kees, Frieder, Sandner, Peter, Stasch, Johannes-Peter and Hofmann, Franz (2017) Inhibition of the TGFβ signalling pathway by cGMP and cGMP‐dependent kinase I in renal fibrosis. FEBS openbio 7 (4), pp. 550-561.

Wittmann, Hans-Joachim and Strasser, Andrea (2017) Competitive association binding kinetic assays: a new tool to detect two different binding orientations of a ligand to its target protein under distinct conditions? Naunyn-Schmiedeberg's Archives of Pharmacology. (In Press) Fulltext not available.

Dorn, Christoph , Nowak, Hartmuth, Weidemann, Caroline, Martini, Stefan, Zeitlinger, Markus, Adamzik, Michael and Kees, Frieder K. (2017) Decreased protein binding of moxifloxacin in patients with sepsis? GMS Infectious Diseases 2017 (5), Doc03.

Koehler, Julia, Verheyen, Leonie, Hedtrich, Sarah, Brandl, Ferdinand P. and Goepferich, Achim M. (2017) Alkaline poly(ethylene glycol)-based hydrogels for a potential use as bioactive wound dressings. Journal of Biomedical Materials Research Part A 105 (12), pp. 3360-3368. Fulltext not available.

Schäfer, Claudia, Göder, Anja, Beyer, Mandy, Kiweler, Nicole, Mahendrarajah, Nisintha, Rauch, Anke, Nikolova, Teodora, Stojanovic, Natasa, Wieczorek, Martin, Reich, Thomas R., Tomicic, Maja T., Linnebacher, Michael, Sonnemann, Jürgen, Dietrich, Sascha, Sellmer, Andreas, Mahboobi, Siavosh, Heinzel, Thorsten, Schneider, Günter and Krämer, Oliver H. (2017) Class I histone deacetylases regulate p53/NF-κB crosstalk in cancer cells. Cellular Signalling 29, pp. 218-225. Fulltext not available.

Gregoritza, Manuel , Messmann, Viktoria, Abstiens, Kathrin, Brandl, Ferdinand and Göpferich, Achim (2017) Controlled Antibody Release from Degradable Thermoresponsive
Hydrogels Cross-Linked by Diels−Alder Chemistry. Biomacromolecules 18, pp. 2410-2418. Fulltext not available.

Makule, Edna, Schmidt, Thomas J. , Heilmann, Jörg and Kraus, Birgit (2017) Diarylheptanoid Glycosides of Morella salicifolia Bark. Molecules 22, p. 2266.

Stojanovic, N., Hassan, Z., Wirth, M., Wenzel, P., Beyer, M., Schäfer, C., Brand, P., Kroemer, A., Stauber, R. H., Schmid, R. M., Arlt, A., Sellmer, A., Mahboobi, S., Rad, R., Reichert, M., Saur, D., Krämer, O. H. and Schneider, G. (2017) HDAC1 and HDAC2 integrate the expression of p53 mutants in pancreatic cancer. Oncogene 36 (13), pp. 1804-1815. Fulltext not available.

Mahendrarajah, Nisintha, Borisova, Marina E., Reichardt, Sigrid, Godmann, Maren, Sellmer, Andreas, Mahboobi, Siavosh, Haitel, Andrea, Schmid, Katharina, Kenner, Lukas , Heinzel, Thorsten, Beli, Petra and Krämer, Oliver H. (2017) HSP90 is necessary for the ACK1-dependent phosphorylation of STAT1 and STAT3. Cellular Signalling 39, pp. 9-17. Fulltext not available.

Guter, Michaela and Breunig, Miriam (2017) Hyaluronan as a promising excipient for ocular drug delivery. European Journal of Pharmaceutics and Biopharmaceutics 113, pp. 34-49. Fulltext not available.

Kuhn, Kilian K., Littmann, Timo, Dukorn, Stefanie, Tanaka, Miho, Keller, Max, Ozawa, Takeaki, Bernhardt, Günther and Buschauer, Armin (2017) In Search of NPY Y4R Antagonists: Incorporation of Carbamoylated Arginine, Aza-Amino Acids, or d-Amino Acids into Oligopeptides Derived from the C-Termini of the Endogenous Agonists. ACS Omega 2 (7), pp. 3616-3631.

Ittner, Karl, Koppenberg, Joachim and Walter, Ute (2017) Indikationsfremde Anwendung von Medikamenten und Medizinprodukten in der Notfallmedizin. Der Notarzt 33 (04), pp. 178-188. Fulltext not available.

Slattery, David A., Neumann, Inga D., Flor, Peter J. and Zoicas, Iulia (2017) Pharmacological modulation of metabotropic glutamate receptor subtype 5 and 7 impairs extinction of social fear in a time-point-dependent manner. Behavioural Brain Research 328, pp. 57-61. Fulltext not available.

Wutz, Daniel-Fabian, Gluhacevic, Dino, Chakrabarti, A., Schmidtkunz, K., Robaa, D., Erdmann, F., Romier, C., Sippl, W., Jung, M. and König, Burkhard (2017) Photochromic histone deacetylase inhibitors based on
dithienylethenes and fulgimides. Organic & Biomolecular Chemistry 15, pp. 4882-4896. Fulltext not available.

Backofen, Michael, Schwach, Gregoire, Koechling, Wolfgang, Weiss, Torsten and Goepferich, Achim (2017) Polyanion based controlled release system for the GnRH-receptor antagonist degarelix. European Journal of Pharmaceutical Sciences 104, pp. 65-71. Fulltext not available.

Tomasetti, Luise and Breunig, Miriam (2017) Preventing Obstructions of Nanosized Drug Delivery
Systems by the Extracellular Matrix. Advanced Healthcare Materials, pp. 1-16. Fulltext not available.

Pegoli, Andrea , She, Xueke, Wifling, David , Hübner, Harald, Bernhardt, Günther, Gmeiner, Peter and Keller, Max (2017) Radiolabeled Dibenzodiazepinone-Type Antagonists Give Evidence of Dualsteric Binding at the M2 Muscarinic Acetylcholine Receptor. Journal of Medicinal Chemistry 60 (8), pp. 3314-3334. Fulltext not available.

Meyer, Andreas Uwe , Wimmer, Alexander and König, Burkhard (2017) Visible-Light-Accelerated C−H Sulfinylation of Heteroarenes. Angewandte Chemie International Edition 56, pp. 409-412. Fulltext not available.

Onuoha, Mary Remigius Agatha (2016) Therapeutic Drug Monitoring of Antipsychotics - HPLC Analytical Method Development and Pharmaceutical Advices to the Ward Clinicians - For Successful Individualized Therapy. PhD, Universität Regensburg.

Strasser, Andrea and Wittmann, Hans-Joachim (2016) Molecular Modelling Approaches for the Analysis of Histamine Receptors and Their Interaction with Ligands. In: Handbook of Experimental Pharmacology. (In Press) Fulltext not available.

Lieb, Sebastian (2016) Investigations on histamine and neuropeptide Y receptors by label-free and label-dependent methods. PhD, Universität Regensburg.

Lieb, Sebastian, Littmann, Timo, Plank, Nicole, Felixberger, Johannes, Tanaka, Miho, Schäfer, Thorsten, Krief, Stéphane, Elz, Sigurd, Friedland, Kristina, Bernhardt, Günther, Wegener, Joachim, Ozawa, Takeaki and Buschauer, Armin (2016) Label-free versus conventional cellular assays: functional investigations on the human histamine H1 receptor. Pharmacological Research 114, pp. 13-26. Fulltext not available.

Wiesneth, Stefan, Heilmann, Jörg and Jürgenliemk, Guido (2016) Total phenolic and tannins determination: A modification of Ph. Eur. 2.8.14 suitable for high-throughput screenings. In: Annual Meeting of the German Pharmaceutical Society (DPhG), 4.-7. Okt. 2016, München, Germany. Fulltext not available.

Sadek, Bassem, Khan, Nadia, Darras, Fouad H., Pockes, Steffen and Decker, Michael (2016) The dual-acting AChE inhibitor and H3 receptor antagonist UW-MD-72 reverses amnesia induced by scopolamine or dizocilpine in passive avoidance paradigm in rats. Physiology & Behavior 165, pp. 383-391. Fulltext not available.

Töpper, Christoph, Steinbach, Cathérine Louise, Dorn, Christoph , Kratzer, Alexander, Wicha, Sebastian G., Schleibinger, Michael, Liebchen, Uwe, Kees, Frieder, Salzberger, Bernd and Kees, Martin G. (2016) Variable linezolid exposure in ICU patients—possible role of drug-drug interactions. Therapeutic Drug Monitoring 38 (5), pp. 573-578. Fulltext not available.

Naporra, Franziska, Gobleder, Susanne, Wittmann, Hans-Joachim, Spindler, Julia, Bodensteiner, Michael, Bernhardt, Günther, Hübner, Harald, Gmeiner, Peter, Elz, Sigurd and Strasser, Andrea (2016) Dibenzo[b,f][1,4]oxazepines and dibenzo[b,e]oxepines: Influence of the chlorine substitution pattern on the pharmacology at the H1R, H4R, 5-HT2AR and other selected GPCRs. Pharmacological Research 113, pp. 610-625. (In Press) Fulltext not available.

Kunath, Julia (2016) Designermoleküle hemmen die Semaphorin 3F Wirkung in vitro, haben aber keinen Einfluss auf den Verlauf der experimentellen Arthritis. PhD, Universität Regensburg.

Untergehrer, Monika (2016) Analytische Untersuchungen zu phenolischen Inhaltsstoffen aus Salicis Cortex unter besonderer Berücksichtigung ihrer Metabolisierung. PhD, Universität Regensburg.

Schlossmann, Jens, Wetzl, Veronika, Schinner, Elisabeth, Kees, Frieder K., Hofmann, Franz and Faerber, Lothar (2016) Involvement of cyclic guanosine monophosphate-dependent protein kinase I in renal antifibrotic effects of serelaxin. Frontiers in Pharmacology 7 (195), pp. 1-27.

Hennig, Robert (2016) Multivalent nanoparticles for the treatment of ocular diseases. PhD, Universität Regensburg.

Wurster, Eva-Christina (2016) Layer-by-Layer assembled thin films for drug delivery: Interactions at the nano-bio interface. PhD, Universität Regensburg.

Korber, Nikolaus and Friedrich, Ute (2016) A Step in Between: [Sn3Bi3]5− and Its Structural Relationship to [Sn3Bi5]3− and [Sn4Bi4]4−. Chemistry Open 5 (4), pp. 306-310.

Kuhn, Kilian K., Ertl, Thomas, Dukorn, Stefanie, Keller, Max, Bernhardt, Günther, Reiser, Oliver and Buschauer, Armin (2016) High affinity agonists of the neuropeptide Y (NPY) Y4 receptor derived from the C-terminal pentapeptide of human pancreatic polypeptide (hPP): synthesis, stereochemical discrimination and radiolabeling. Journal of Medicinal Chemistry 59 (13), pp. 6045-6058. Fulltext not available.

Gobleder, Susanne (2016) Synthesis and pharmacological characterization of new histamine H1-/H4-receptor ligands derived from the atypical antipsychotic drug Clozapine. PhD, Universität Regensburg.

Wiesneth, Stefan (2016) Polyphenole aus Salix – Neue Teile im phytochemischen Puzzle (Polyphenols from Salix – new insights into the phytochemical composition). In: 3. Doktorandenkolleg der WALA Heilmittel GmbH (PhD students meeting), 30. April 2016, Bad Boll / Eckwälden, Germany. Fulltext not available.

Kratzer, Alexander Ludwig (2016) Entwicklung und Erprobung von HPLC-basierten Methoden für das Therapeutische Drug-Monitoring von Betalaktam-Antibiotika, Linezolid und Tigecyclin – Bestimmung von freien und totalen Konzentrationen im Plasma von Intensivpatienten. PhD, Universität Regensburg.

Geyer, Roland, Nordemann, Uwe, Strasser, Andrea, Wittmann, Hans-Joachim and Buschauer, Armin (2016) Conformational restriction and enantioseparation increase potency and selectivity of cyanoguanidine-type histamine H4 receptor agonists. Journal of Medicinal Chemistry 59 (7), pp. 3452-3470. Fulltext not available.

Huber, Stefan (2016) Investigations on bendamustine esters as new antitumor agents and the role of ABCG2 as a surrogate marker of breast cancer initiating cells. PhD, Universität Regensburg.

Limmer, Franziska (2016) Funktionelle Analyse der cGMP-abhängigen Proteinkinase I in der Niere, insbesondere im dicken aufsteigenden Ast der Henle-Schleife. PhD, Universität Regensburg.

Edalat, Lena, Stegen, Benjamin, Klumpp, Lukas, Haehl, Erik, Schilbach, Karin, Lukowski, Robert, Kühnle, Matthias, Bernhardt, Günther, Buschauer, Armin, Zips, Daniel, Ruth, Peter and Huber, Stephan M. (2016) BK K+ channel blockade inhibits radiation-induced migration/brain infiltration of glioblastoma cells. Oncotarget 7 (12), pp. 14259-14278. Fulltext not available.

Felixberger, Johannes (2016) Luciferase complementation for the determination of arrestin recruitment: Investigations at histamine and NPY receptors. PhD, Universität Regensburg.

Stangl, Hubert Werner (2016) Arthritis and cholinergic transition of sympathetic nerve fibers. PhD, Universität Regensburg.

Vögeler, Jessica (2016) Pharmakotherapie und Humanpharmakologische Untersuchungen bei Patienten mit DME (Diabetisches Makulaödem) und PDR (Proliferative Diabetische Retinopathie) anhand klinischer Parameter und inflammatorischer Biomarker. PhD, Universität Regensburg.

Lorenz, Peter, Knittel, Diana N., Conrad, Jürgen, Lotter, Eva M., Heilmann, Jörg, Stintzing, Florian C. and Kammerer, Dietmar R. (2016) 1-Acetyl-3-[(3R)-hydroxyfatty acyl]glycerols: Lipid Compounds fromEuphrasia rostkovianaHayneandE. tetraquetra(Bréb.)Arrond. Chemistry & Biodiversity 13 (5), pp. 602-612. Fulltext not available.

Hammer, Sebastian, Gobleder, Susanne, Naporra, Franziska, Wittmann, Hans-Joachim, Elz, Sigurd, Heinrich, Markus and Strasser, Andrea (2016) 2,4-Diaminopyrimidines as dual ligands at the histamine H1 and H4 receptor - H1/H4-receptor selectivity. Bioorganic & Medicinal Chemistry Letters 26, pp. 292-300. Fulltext not available.

Dolles, Dominik, Nimczick, Martin, Scheiner, Matthias, Ramler, Jacqueline, Stadtmüller, Patricia, Sawatzky, Edgar, Drakopoulos, Antonios, Sotriffer, Christoph, Wittmann, Hans-Joachim, Strasser, Andrea and Decker, Michael (2016) Aminobenzimidazoles and structural isomers as templates for dual-acting butyrylcholinesterase inhibitors and hCB2R ligands to combat neurodegenerative disorders. ChemMedChem 11 (12), pp. 1270-1283. Fulltext not available.

Bucher, Felicitas , Walz, Johanna M., Bühler, Anima, Aguilar, Edith, Lange, Clemens, Diaz-Aguilar, Sophia, Martin, Gottfried, Schlunck, Günther, Agostini, Hansjürgen, Friedlander, Martin and Stahl, Andreas (2016) CNTF Attenuates Vasoproliferative Changes Through Upregulation of SOCS3 in a Mouse-Model of Oxygen-Induced Retinopathy. Investigative Opthalmology & Visual Science 57 (10), p. 4017. Fulltext not available.

Hennig, Robert, Kuespert, Sabrina, Haunberger, Alexandra, Goepferich, Achim and Fuchshofer, Rudolf (2016) Cyclic RGD peptides target human trabecular meshwork cells while ameliorating connective tissue growth factor-induced fibrosis. Journal of Drug Targeting 24 (10), pp. 952-959. Fulltext not available.

Gregoritza, Manuel, Messmann, Viktoria, Goepferich, Achim and Brandl, Ferdinand (2016) Design of hydrogels for delayed antibody release utilizing hydrophobic association and Diels-Alder chemistry in tandem. Journal of Materials Chemistry B 4 (19), pp. 3398-3408. Fulltext not available.

Gregoritza, Manuel, Messmann, Viktoria, Goepferich, Achim M. and Brandl, Ferdinand P. (2016) Design of hydrogels for delayed antibody release utilizing hydrophobic association and Diels–Alder chemistry in tandem. Journal of Materials Chemistry B 4 (19), pp. 3398-3408. Fulltext not available.

Sawatzky, Edgar, Wehle, Sarah, Kling, Beata, Wendrich, Jan, Bringmann, Gerhard, Sotriffer, Christoph A., Heilmann, Jörg and Decker, Michael (2016) Discovery of Highly Selective and Nanomolar Carbamate-Based Butyrylcholinesterase Inhibitors by Rational Investigation into Their Inhibition Mode. Journal of Medicinal Chemistry 59 (5), pp. 2067-2082. Fulltext not available.

Obreque-Balboa, José-Esteban, Sun, Qiu, Bernhardt, Günther, König, Burkhard and Buschauer, Armin (2016) Flavonoid derivatives as selective ABCC1 modulators: Synthesis and functional characterization. European Journal of Medicinal Chemistry 109, pp. 124-133. Fulltext not available.

Hering, Thea, Mühldorf, Bernd, Wolf, Robert and König, Burkhard (2016) Halogenase-Inspired Oxidative Chlorination Using Flavin
Photocatalysis. Angewandte Chemie International Edition 55, pp. 5342-5345. Fulltext not available.

Kariminia, Amina, Holtan, Shernan G., Ivison, Sabine, Rozmus, Jacob, Hebert, Marie-Josée, Martin, Paul J., Lee, Stephanie J., Wolff, Daniel, Subrt, Peter, Abdossamadi, Sayeh, Sung, Susanna, Storek, Jan, Levings, Megan, Aljurf, Mahmoud, Arora, Mukta, Cutler, Corey, Gallagher, Geneviève, Kuruvilla, John, Lipton, Jeff, Nevill, Thomas J., Newell, Laura F., Panzarella, Tony, Pidala, Joseph, Popradi, Gizelle, Szwajcer, David, Tay, Jason , Toze, Cynthia L., Walker, Irwin, Couban, Stephen, Storer, Barry E. and Schultz, Kirk R. (2016) Heterogeneity of chronic graft-versus-host disease biomarkers: association with CXCL10 and CXCR3+ NK cells. Blood 127 (24), pp. 3082-3091. Fulltext not available.

Dove, Stefan (2016) Mammalian Nucleotidyl Cyclases and Their Nucleotide Binding Sites. In: Seifert, Roland, (ed.) Non-canonical Cyclic Nucleotides. Handbook of Experimental Pharmacology, 238. Springer International Publishing, Cham, Switzerland, pp. 49-66. ISBN 978-3-319-52673-7 (online), 978-3-319-52671-3 (print). Fulltext not available.

Keller, Max, Kuhn, Kilian K., Einsiedel, Jürgen, Hübner, Harald, Biselli, Sabrina, Mollereau, Catherine , Wifling, David, Svobodova, Jaroslava, Bernhardt, Günther, Cabrele, Chiara , Vanderheyden, Patrick, Gmeiner, Peter and Buschauer, Armin (2016) Mimicking of arginine by functionalized Nω-carbamoylated arginine as a new broadly applicable approach to labeled bioactive peptides: high affinity angiotensin, neuropeptide Y, neuropeptide FF and neurotensin receptor ligands as examples. Journal of Medicinal Chemistry 59 (5), pp. 1925-1945. Fulltext not available.

Gregoritza, Manuel, Goepferich, Achim and Brandl, Ferdinand (2016) Polyanions effectively prevent protein conjugation and activity loss during hydrogel cross-linking. Journal of Controlled Release 238, pp. 92-102. Fulltext not available.

Khan, Nadia, Saad, Ali, Nurulain, Syed M., Darras, Fouad H., Decker, Michael and Sadek, Bassem (2016) The dual-acting H3 receptor antagonist and AChE inhibitor UW-MD-71 dose-dependently enhances memory retrieval and reverses dizocilpine-induced memory impairment in rats. Behavioural Brain Research 297, pp. 155-164. Fulltext not available.

Kratzer, Alexander, Kees, Frieder and Dorn, Christoph (2016) Unbound fraction of fluconazole and linezolid in human plasma as determined by ultrafiltration: Impact of membrane type. Journal of Chromatography B 1039, pp. 74-78. Fulltext not available.

Huang, Guozheng , Schramm, Simon, Heilmann, Jörg, Biedermann, David, Křen, Vladimír and Decker, Michael (2016) Unconventional application of the Mitsunobu reaction: Selective flavonolignan dehydration yielding hydnocarpins. Beilstein Journal of Organic Chemistry 12, pp. 662-669. Fulltext not available.

Koehler, Julia, Wallmeyer, Leonie, Hedtrich, Sarah, Goepferich, Achim M. and Brandl, Ferdinand P. (2016) pH-Modulating Poly(ethylene glycol)/Alginate Hydrogel Dressings for the Treatment of Chronic Wounds. Macromolecular Bioscience 17 (5), p. 1600369. Fulltext not available.

Kirchhof, Susanne (2015) Diels Alder Hydrogels as Intraocular Drug Delivery Systems for Antibodies. PhD, Universität Regensburg.

Wiesneth, Stefan, Petereit, Frank and Jürgenliemk, Guido (2015) Salix daphnoides: A Screening for oligomeric and polymeric flavan-3-ols. In: 7th International Conference on Polyphenols and Health (ICPH), 27.-30. Okt. 2015, Tours, France. Fulltext not available.

Meinel, Thomas Raphael, make_name_string expected hash reference , make_name_string expected hash reference and make_name_string expected hash reference (2015) Neuronale alpha-adrenerge Stimulation von IFN-gamma, IL-6 und CXCL1 in murinen Milzen im Tiermodell der Arthritisspätphase. PhD, Universität Regensburg.

Nguyen, Tri Hieu (2015) Phytochemical and biological investigation of the bark of Garcinia fusca Pierre. PhD, Universität Regensburg.

Helm, Klaus (2015) Synthese und funktionelle In-vitro-Pharmakologie neuer Liganden des 5-HT2A-Rezeptors aus der Klasse der Tryptamine. PhD, Universität Regensburg.

Werner, Kristin, Kälble, Solveig, Wolter, Sabine, Schneider, Erich H. , Buschauer, Armin, Neumann, Detlef and Seifert, Roland (2015) Flow cytometric analysis with a fluorescent formyl peptide receptor ligand as a new method to study the pharmacological profile of the histamine H2-receptor. Naunyn Schmiedebergs Archives of Pharmacology 388 (10), pp. 1039-1052. Fulltext not available.

Wolferstetter, Stefanie, Reinders, Jörg, Schwede, Frank, Ruth, Peter, Schinner, Elisabeth and Schlossmann, Jens (2015) Interaction of cCMP with the cGK, cAK and MAPK Kinases in Murine Tissues. PLoS ONE 10 (5), e0126057.

Rothenhöfer, Martin, Grundmann, Marco, Bernhardt, Günther, Matysik, Frank-Michael and Buschauer, Armin (2015) High performance anion exchange chromatography with pulsed amperometric detection (HPAEC–PAD) for the sensitive determination of hyaluronan oligosaccharides. Journal of Chromatography B 988 (C), pp. 106-115. Fulltext not available.

Tetens, J. , Heuer, C., Heyer, I., Klein, Matthias S. , Gronwald, Wolfram, Junge, W., Oefner, Peter J. , Thaller, G. and Krattenmacher, N. (2015) Polymorphisms within the APOBR gene are highly associated with milk levels of prognostic ketosis biomarkers in dairy cows. Physiol. Genomics 47 (4), pp. 129-137. Fulltext not available.

Wifling, David (2015) Constitutive activity of the human histamine H4 receptor: Molecular modelling, binding and functional studies on wild-type and mutant H4R orthologs. PhD, Universität Regensburg.

Wurster, Eva-Christina, Liebl, Renate, Michaelis, Stefanie, Robelek, Rudolf, Wastl, Daniel S. , Giessibl, Franz J. , Goepferich, Achim and Breunig, Miriam (2015) Oligolayer-Coated Nanoparticles: Impact of Surface Topography at the Nanobio Interface. ACS applied materials & interfaces 7, pp. 7891-7900. Fulltext not available.

Wiesneth, Stefan, Petereit, Frank and Jürgenliemk, Guido (2015) Polymere Proanthocyanidine aus der Rinde von Salix daphnoides (Polymeric proanthocyanidins from the bark of Salix daphnoides). In: 4. Young Researcher Meeting, 13.-14. März 2015, Münster, Germany. Fulltext not available.

Mahli, Abdo (2015) Novel in vitro model for combined effects of alcohol and free fatty acids on hepatocellular lipid accumulation and inflammation. PhD, Universität Regensburg.

Wifling, David , Bernhardt, Günther, Dove, Stefan and Buschauer, Armin (2015) The extracellular loop 2 (ECL2) of the human histamine H4 receptor substantially contributes to ligand binding and constitutive activity. PLoS One 10 (1), pp. 1-14.

Baumeister, Paul, Erdmann, Daniela, Biselli, Sabrina, Kagermeier, Nicole, Elz, Sigurd, Bernhardt, Günther and Buschauer, Armin (2015) 3HUR-DE257: Development of a tritium-labeled squaramide-type selective histamine H2 receptor antagonist. ChemMedChem 10 (1), pp. 83-93. Fulltext not available.

Dolles, Dominik, Nimczick, Martin, Scheiner, Matthias, Ramler, Jacqueline, Stadtmüller, Patricia, Sawatzky, Edgar, Drakopoulos, Antonios , Sotriffer, Christoph, Wittmann, Hans-Joachim, Strasser, Andrea and Decker, Michael (2015) Aminobenzimidazoles and Structural Isomers as Templates for Dual-Acting Butyrylcholinesterase Inhibitors andhCB2R Ligands To Combat Neurodegenerative Disorders. ChemMedChem 11 (12), pp. 1270-1283. Fulltext not available.

Wittmann, Hans-Joachim and Strasser, Andrea (2015) Binding pathway of histamine to the hH4R, observed by unconstrained molecular dynamics. Bioorganic & Medicinal Chemistry Letters 25, pp. 1259-1268. Fulltext not available.

Hennig, Robert, Veser, Anika, Kirchhof, Susanne and Goepferich, Achim (2015) Branched Polymer–Drug Conjugates for Multivalent Blockade of Angiotensin II Receptors. Molecular Pharmaceutics 12 (9), pp. 3292-3302. Fulltext not available.

Schinner, Elisabeth, Wetzl, Veronika and Schlossmann, Jens (2015) Cyclic Nucleotide Signalling in Kidney Fibrosis. International Journal of Molecular Sciences 16, pp. 2320-2351.

Kirchhof, Susanne, Gregoritza, Manuel, Messmann, Viktoria, Hammer, Nadine, Göpferich, Achim and Brandl, Ferdinand (2015) Diels-​Alder hydrogels with enhanced stability: First step toward controlled release of bevacizumab. European Journal of Pharmaceutics and Biopharmaceutics 96, pp. 217-225. Fulltext not available.

Kirchhof, Susanne, Abrami, Michela, Messmann, Viktoria, Hammer, Nadine, Goepferich, Achim , Grassi, Mario and Brandl, Ferdinand (2015) Diels–Alder hydrogels for controlled antibody release: Correlation between mesh size and release rate. Molecular Pharmaceutics 12 (9), pp. 3358-3368. Fulltext not available.

Lübker, Carolin, Dove, Stefan, Tang, Wei-Jen , Bieber Urbauer, Ramona J., Moskovitz, Jackob, Urbauer, Jeffrey L. and Seifert, Roland (2015) Different Roles of N-Terminal and C-Terminal Domains in Calmodulin for Activation of Bacillus anthracis Edema Factor. Toxins 7 (7), pp. 2598-2614.

Kagermeier, Nicole, Werner, Kristin, Keller, Max, Baumeister, Paul, Bernhardt, Günther, Seifert, Roland and Buschauer, Armin (2015) Dimeric carbamoylguanidine-type histamine H2 receptor ligands: A new class of potent and selective agonists. Bioorganic & Medicinal Chemistry 23 (14), pp. 3957-3969. Fulltext not available.

Arndt, Stephanie, Wacker, Eva, Dorn, Christoph, Koch, Andreas, Saugspier, Michael, Thasler, W. E., Hartmann, Arndt, Bosserhoff, Anja-Katrin and Hellerbrand, Claus (2015) Enhanced expression of BMP6 inhibits hepatic fibrosis in non-alcoholic fatty liver disease. Gut 64 (6), pp. 973-981.

Beermann, Silke, Bernhardt, Guenther, Seifert, Roland, Buschauer, Armin and Neumann, Detlef (2015) Histamine H1- and H4-receptor signaling cooperatively regulate MAPK activation. Biochemical Pharmacology 98 (3), pp. 432-439. Fulltext not available.

Beermann, Silke, Bernhardt, Guenther, Seifert, Roland, Buschauer, Armin and Neumann, Detlef (2015) Histamine H1- and H4-receptor signaling cooperatively regulate MAPK activation. Biochemical Pharmacology 98 (3), pp. 432-439. Fulltext not available.

Strasser, Andrea and Buschauer, Armin (2015) Histaminrezeptoren. Pharmakon 3 (2), pp. 109-116. Fulltext not available.

Kirchhof, Susanne, Goepferich, Achim and Brandl, Ferdinand (2015) Hydrogels in ophthalmic applications. European Journal of Pharmaceutics and Biopharmaceutics 95, part B, pp. 227-238. Fulltext not available.

Radons, Jürgen, Falk, Werner and Dove, Stefan (2015) Identification of critical regions within the TIR domain of IL-1 receptor type I. The international journal of biochemistry & cell biology 68, pp. 15-20. Fulltext not available.

Zenger, Katharina, Dutta, Subhajit, Wolff, Horst, Genton, Marc G. and Kraus, Birgit (2015) In vitro structure-toxicity relationship of chalcones in human hepatic stellate cells. Toxicology 336, pp. 26-33. Fulltext not available.

Keller, Max, Tränkle, Christian, She, Xueke, Pegoli, Andrea , Bernhardt, Günther, Buschauer, Armin and Read, Roger W. (2015) M2 subtype preferring dibenzodiazepinone-type muscarinic receptor ligands: effect of chemical homo-dimerization on orthosteric (and allosteric?) binding. Bioorganic & Medicinal Chemistry 23 (14), pp. 3970-3990. Fulltext not available.

Lübker, Carolin, Bieber-Urbauer, Ramona J., Moskovitz, Jackob, Dove, Stefan, Weisemann, Jasmin , Fedorova, Maria, Urbauer, Jeffrey L. and Seifert, Roland (2015) Membranous adenylyl cyclase 1 activation is regulated by oxidation of N- and C-terminal methionine residues in calmodulin. Biochemical Pharmacology 93 (2), pp. 196-209. Fulltext not available.

Strasser, Andrea, Wittmann, Hans-Joachim, Schneider, Erich H. and Seifert, Roland (2015) Modulation of GPCRs by monovalent cations and anions. Naunyn-Schmiedeberg's Archives of Pharmacology 388, pp. 363-380. Fulltext not available.

Wifling, David , Löffel, Karolin, Nordemann, Uwe, Strasser, Andrea, Bernhardt, Günther, Dove, Stefan, Seifert, Roland and Buschauer, Armin (2015) Molecular determinants for the high constitutive activity of the human histamine H4 receptor: Functional studies on orthologs and mutants. British Journal of Pharmacology 172, pp. 785-798. Fulltext not available.

Kaczor, Agnieszka , Guixa-Gonzalez, Ramon, Carrio, Pau, Poso, Antti, Dove, Stefan, Pastor, Manuel and Selent, Jana (2015) Multi-Component Protein - Protein Docking Based Protocol with External Scoring for Modeling Dimers of G Protein-Coupled Receptors. Molecular Informatics 34 (4), pp. 246-255. Fulltext not available.

Hennig, Robert, Pollinger, Klaus, Tessmar, Joerg and Göpferich, Achim (2015) Multivalent targeting of AT1 receptors with angiotensin II-​functionalized nanoparticles. Journal of Drug Targeting, pp. 1-9. Fulltext not available.

Keller, Max, Weiss, Stefan, Hutzler, Christoph , Kuhn, Kilian K., Mollereau, Catherine , Dukorn, Stefanie, Schindler, Lisa, Bernhardt, Günther, König, Burkhard and Buschauer, Armin (2015) N(omega)-carbamoylation of the argininamide moiety: an avenue to insurmountable NPY Y1 receptor antagonists and a radiolabeled selective high affinity molecular tool ([3H]UR-MK299) with extended residence time. Journal of Medicinal Chemistry 58 (22), pp. 8834-8849. Fulltext not available.

Sun, Qiu, Heilmann, Jörg and König, Burkhard (2015) Natural phenolic metabolites with anti-angiogenic properties – a review from the chemical point of view. Beilstein Journal of Organic Chemistry 11, pp. 249-264.

Kirchhof, Susanne, Strasser, Andrea, Wittmann, Hans-Joachim, Messmann, Viktoria, Hammer, Nadine, Goepferich, Achim and Brandl, Ferdinand (2015) New insights into the cross-linking and degradation mechanism of Diels–Alder hydrogels. Journal of Materials Chemistry B 3, pp. 449-457.

Kirchhof, Susanne, Strasser, Andrea, Wittmann, Hans-Joachim, Messmann, Viktoria, Hammer, Nadine, Goepferich, Achim M. and Brandl, Ferdinand P. (2015) New insights into the cross-linking and degradation mechanism of Diels–Alder hydrogels. Journal of Materials Chemistry B 3 (3), pp. 449-457. Fulltext not available.

Aziz, Atiqullah, Gierth, Michael, Rink, Michael, Schmid, Marianne, Chun, Felix K., Dahlem, Roland, Roghmann, Florian, Palisaar, Rein-Jüri, Noldus, Joachim, Ellinger, Jörg , Müller, Stefan C., Pycha, Armin, Martini, Thomas, Bolenz, Christian, Moritz, Rudolf, Herrmann, Edwin, Keck, Bastian, Wullich, Bernd, Mayr, Roman, Fritsche, Hans-Martin, Burger, Maximilian, Bastian, Patrick J., Seitz, Christian, Brookman-May, Sabine, Xylinas, Evanguelos, Shariat, Shahrokh F., Fisch, Margit and May, Matthias (2015) Optimizing outcome reporting after radical cystectomy for organ-confined urothelial carcinoma of the bladder using oncological trifecta and pentafecta. World Journal of Urology 33 (12), pp. 1945-1950. Fulltext not available.

Wicha, Sebastian G., Haak, Thomas, Zink, Karl, Kees, Frieder, Kloft, Charlotte and Kees, Martin G. (2015) Population pharmacokinetics and target attainment analysis of moxifloxacin in patients with diabetic foot infections. The Journal of Clinical Pharmacology 55 (6), pp. 639-646. Fulltext not available.

Hammer, Nadine, Brandl, Ferdinand, Kirchhof, Susanne, Messmann, Viktoria and Goepferich, Achim (2015) Protein compatibility of selected cross-linking reactions for hydrogels. Macromol. Biosci. 15 (3), pp. 405-413. Fulltext not available.

Chen, Xinyu, Klöckner, Jessika, Holze, Janine, Zimmermann, Cornelia, Seemann, Wiebke K., Schrage, Ramona, Bock, Andreas , Mohr, Klaus, Tränkle, Christian, Holzgrabe, Ulrike and Decker, Michael (2015) Rational Design of Partial Agonists for the Muscarinic M1 Acetylcholine Receptor. Journal of Medicinal Chemistry 58 (2), pp. 560-576. Fulltext not available.

Stasch, Johannes-Peter, Schlossmann, Jens and Hocher, Berthold (2015) Renal effects of soluble guanylate cyclase stimulators and activators: A review of the preclinical evidence. Current Opinion in Pharmacology 21, pp. 95-104. Fulltext not available.

Rosentritt, Martin, Preis, Verena, Behr, Michael, Sereno, Nuno and Kolbeck, Carola (2015) Shear bond strength between veneering composite and PEEK after different surface modifications. Clinical Oral Investigations 19 (3), pp. 739-744. Fulltext not available.

Huber, Stefan, Antoni, Frauke, Schickaneder, Christian, Schickaneder, Helmut, Bernhardt, Günther and Buschauer, Armin (2015) Stabilities of neutral and basic esters of bendamustine in plasma compared to the parent compound: Kinetic investigations by HPLC. Journal of Pharmaceutical and Biomedical Analysis 104, pp. 137-143. Fulltext not available.

Reinartz, Michael T. , Kälble, Solveig, Littmann, Timo, Ozawa, Takeaki, Dove, Stefan, Kaever, Volkhard, Wainer, Irving W. and Seifert, Roland (2015) Structure-bias relationships for fenoterol stereoisomers in six molecular and cellular assays at the β2-adrenoceptor. Naunyn-Schmiedeberg's archives of pharmacology 388 (1), pp. 51-65. Fulltext not available.

Huber, Stefan, Wege, Anja K., Bernhardt, Günther, Buschauer, Armin and Brockhoff, Gero (2015) Topotecan-induced ABCG2 expression in MCF-7 cells is associated with decreased CD24 and EpCAM expression and a loss of tumorigenicity. Cytometry A 87 (8), pp. 707-716. Fulltext not available.

Herrnberger, Leonie, Hennig, Robert, Kremer, Werner, Hellerbrand, Claus, Goepferich, Achim , Kalbitzer, Hans Robert and Tamm, Ernst R. (2014) Formation of Fenestrae in Murine Liver Sinusoids Depends on Plasmalemma Vesicle-Associated Protein and Is Required for Lipoprotein Passage. PLoS ONE 9 (12), e115005.

Cuboni, Serena, Devigny, Christian, Hoogeland, Bastiaan, Strasser, Andrea, Pomplun, Sebastian, Hauger, Barbara, Höfner, Georg, Wanner, Klaus, Eder, Matthias , Buschauer, Armin, Holsboer, Florian and Hausch, Felix (2014) Loratadine and analogs: Discovery and preliminary SAR of inhibitors of the amino acid transporter B0AT2. Journal of Medicinal Chemistry 57 (22), pp. 9473-9479. Fulltext not available.

Dulla, Balakrishna (2014) Synthesis and pharmacological characterization of novel N & O containing heterocyclic compounds as potential therapeutic agents. PhD, Universität Regensburg.

Baumeister, Paul (2014) Molecular tools for G-protein coupled receptors:
Synthesis, pharmacological characterization and [3H]-labeling of subtype-selective ligands for histamine H4 and NPY Y2 receptors. PhD, Universität Regensburg.

Hennig, Robert, Pollinger, Klaus, Veser, Anika, Breunig, Miriam and Goepferich, Achim (2014) Nanoparticle multivalency counterbalances the ligand affinity loss upon PEGylation. Journal of Controlled Release 194, pp. 20-27. Fulltext not available.

Haunschild, Gundula (2014) Nachweis und molekulare Charakterisierung EpCAM-positiver Zellen im Knochenmark von Mammakarzinom-Patientinnen. PhD, Universität Regensburg.

Schramm, Andrea (2014) Analyse renaler Funktionen der cGMP-abhängigen Proteinkinase II. PhD, Universität Regensburg.

Wittmann, Hans-Joachim, Seifert, Roland and Strasser, Andrea (2014) Mathematical analysis of the sodium sensitivity of the human histamine H3 receptor. In silico pharmacology 2.

Tauber, Philipp (2014) Untersuchungen zur Pathogenese von primärem Hyperaldosteronismus in neugeborenen Task3-/- Mäusen und adrenokortikalen Zellen mit KCNJ5-Mutation. PhD, Universität Regensburg.

Herrmann, Josef M., Untergehrer, Monika, Jürgenliemk, Guido, Heilmann, Jörg and König, Burkhard (2014) Synthesis of Phenyl-1-benzoxepinols Isolated from Butcher’s Broom and Analogous Benzoxepines. European Journal of Organic Chemistry 2014 (15), pp. 3170-3181. Fulltext not available.

Dove, Stefan (2014) Multivariate analysis of hydrophobic descriptors. ADMET & DMPK 2 (1), pp. 3-17.

Dove, Stefan, Danker, Kerstin Yvonne, Stasch, Johannes-Peter, Kaever, Volkhard and Seifert, Roland (2014) Structure/Activity Relationships of (M)ANT- and TNP-Nucleotides for Inhibition of Rat Soluble Guanylyl Cyclase alpha(1)beta(1). Molecular Pharmacology 85 (4), pp. 598-607. Fulltext not available.

Rothenhöfer, Martin (2014) Analytical approaches to the study of hyaluronan and hyaluronidases: Development and application of hyphenated chromatographic and electrophoretic methods. PhD, Universität Regensburg.

Bücherl, Daniel (2014) Isolation of kaempferol glycosides from Ginkgo biloba leaves and synthesis, identification and quantification of their major in vivo metabolites. PhD, Universität Regensburg.

Darras, Fouad, Pockes, Steffen, Huang, Guozheng , Wehle, Sarah, Strasser, Andrea, Wittmann, Hans-Joachim, Nimczick, Martin, Sotriffer, Christoph and Decker, Michael (2014) Synthesis, biological evaluation, and computational studies of tri- and tetracyclic nitrogen-bridgehead compounds as potent dual-acting AChE inhibitors and hH3 receptor antagonists. ACS Chemical Neuroscience 5 (3), pp. 225-242. Fulltext not available.

Darras, Fouad H., Wehle, Sarah, Huang, Guozheng , Sotriffer, Christoph A. and Decker, Michael (2014) Amine substitution of quinazolinones leads to selective nanomolar AChE inhibitors with ‘inverted’ binding mode. Bioorganic & Medicinal Chemistry 22 (17), pp. 4867-4881. Fulltext not available.

Kremb, Stephan, Helfer, Markus, Kraus, Birgit, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference and make_name_string expected hash reference (2014) Aqueous Extracts of the Marine Brown Alga Lobophora variegata Inhibit HIV-1 Infection at the Level of Virus Entry into Cells. PloS ONE 9, e103895.

Pollinger, Klaus, Hennig, Robert, Bauer, Stefanie, Breunig, Miriam, Tessmar, Joerg , Buschauer, Armin, Witzgall, Ralph and Göpferich, Achim (2014) Biodistribution of quantum dots in the kidney after intravenous injection. Journal of Nanoscience and Nanotechnology 14 (5), pp. 3313-3319. Fulltext not available.

Pannem, Rajeswara Rao, Dorn, Christoph, Ahlqvist, Kristofer, Bosserhoff, Anja K. , Hellerbrand, Claus and Massoumi, Ramin (2014) CYLD controls c-MYC expression through the JNK-dependent signaling pathway in hepatocellular carcinoma. Carcinogenesis 35 (2), pp. 461-468.

Hammer, Nadine, Brandl, Ferdinand, Kirchhof, Susanne and Goepferich, Achim (2014) Cleavable carbamate linkers for controlled protein delivery from hydrogels. Journal of Controlled Release 183, pp. 67-76. Fulltext not available.

Schweizer, Daniel, Serno, Tim and Goepferich, Achim (2014) Controlled release of therapeutic antibody formats. European Journal of Pharmaceutics and Biopharmaceutics 88 (2), pp. 291-309. Fulltext not available.

Darras, Fouad H., Kling, Beata, Sawatzky, Edgar, Heilmann, Jörg and Decker, Michael (2014) Cyclic acyl guanidines bearing carbamate moieties allow potent and dirigible cholinesterase inhibition of either acetyl- or butyrylcholinesterase. Bioorganic & Medicinal Chemistry 22 (17), pp. 5020-5034. Fulltext not available.

Huang, Guozheng , Pemp, Daniela, Stadtmüller, Patricia, Nimczick, Martin, Heilmann, Jörg and Decker, Michael (2014) Design, synthesis and in vitro evaluation of novel uni- and bivalent ligands for the cannabinoid receptor type 1 with variation of spacer length and structure. Bioorganic & Medicinal Chemistry Letters 24 (17), pp. 4209-4214. Fulltext not available.

Kratzer, Alexander, Liebchen, Uwe, Schleibinger, Michael, Kees, Martin G. and Kees, Frieder (2014) Determination of free vancomycin, ceftriaxone, cefazolin and ertapenem in plasma by ultrafiltration: Impact of experimental conditions. Journal of Chromatography B 961, pp. 97-102. Fulltext not available.

Schramm, Andrea, Schinner, Elisabeth, Huettner, Johannes P., Kees, Frieder, Tauber, Philipp, Hofmann, Franz and Schlossmann, Jens (2014) Function of cGMP-dependent protein kinase II in volume load-induced diuresis. Pflügers Archiv - European Journal of Physiology 466 (10), pp. 2009-2018. Fulltext not available.

Wolter, Sabine, Dove, Stefan, Golombek, Marina, Schwede, Frank and Seifert, Roland (2014) N4-monobutyryl-cCMP activates PKA RIα and PKA RIIα more potently and with higher efficacy than PKG Iα in vitro but not in vivo. Naunyn-Schmiedeberg's archives of pharmacology 387 (12), pp. 1163-1175. Fulltext not available.

Werner, Kristin, Neumann, Detlef , Buschauer, Armin and Seifert, Roland (2014) No evidence for histamine H4-receptor in human monocytes. Journal of Pharmacology and Experimental Therapeutics 351 (3), pp. 519-526. Fulltext not available.

Wager, Eva, Wittmann, Hans-Joachim, Elz, Sigurd and Strasser, Andrea (2014) Pharmacological profile of astemizole-derived compounds at the histamine H1 and H4 receptor - H1/H4 receptor selectivity. Naunyn-Schmiedeberg's Archives of Pharmacology 387, pp. 235-250. Fulltext not available.

Patrucco, Enrico, Domes, Katrin, Sbroggió, Mauro , Blaich, Anne, Schlossmann, Jens , Desch, Matthias, Rybalkin, Sergei D., Beavo, Joseph A., Lukowski, Robert and Hofmann, Franz (2014) Roles of cGMP-dependent protein kinase I (cGKI) and PDE5 in the regulation of Ang II-induced cardiac hypertrophy and fibrosis. Proceedings of the National Academy of Sciences 111 (35), pp. 12925-12929. Fulltext not available.

Luschmann, Christoph, Tessmar, Joerg , Schoeberl, Simon, Strauss, O., Luschmann, Karl and Goepferich, Achim (2014) Self-​assembling colloidal system for the ocular administration of cyclosporine A. Cornea 33 (1), pp. 77-81. Fulltext not available.

Nimczick, Martin, Pemp, Daniela, Darras, Fouad H., Chen, Xinyu, Heilmann, Jörg and Decker, Michael (2014) Synthesis and biological evaluation of bivalent cannabinoid receptor ligands based on hCB2R selective benzimidazoles reveal unexpected intrinsic properties. Bioorganic & Medicinal Chemistry 22 (15), pp. 3938-3946. Fulltext not available.

Geyer, Roland, Kaske, Melanie, Baumeister, Paul and Buschauer, Armin (2014) Synthesis and functional characterization of imbutamine analogs as histamine H3 and H4 receptor ligands. Archiv der Pharmazie (Weinheim, Germany) 347 (2), pp. 77-88. Fulltext not available.

Jirásek, Petr, Amslinger, Sabine and Heilmann, Jörg (2014) Synthesis of Natural and Non-natural Curcuminoids and their Neuroprotective Activity against Glutamate-induced Oxidative Stress in HT-22 Cells. J. Nat. Prod. 77, pp. 2206-2217. Fulltext not available.

Sun, Qiu, Schmidt, Sebastian, Tremmel, Martina, Heilmann, Jörg and König, Burkhard (2014) Synthesis of natural-like acylphloroglucinols with anti-proliferative, anti-oxidative and tube-formation inhibitory activity. European Journal of Medicinal Chemistry 85, pp. 621-628. Fulltext not available.

Geyer, Roland, Igel, Patrick, Kaske, Melanie, Elz, Sigurd and Buschauer, Armin (2014) Synthesis, SAR and selectivity of 2-acyl- and 2-cyano-1-hetarylalkyl-guanidines at the four histamine receptor subtypes: a bioisosteric approach. MedChemComm 5 (1), pp. 72-81. Fulltext not available.

Macabeo, Allan Patrick G., Martinez, Franze Perry A., Kurtán, Tibor , Tóth, László, Mándi, Attila , Schmidt, Sebastian, Heilmann, Jörg, Alejandro, Grecebio Jonathan D., Knorn, Matthias, Dahse, Hans-Martin and Franzblau, Scott G. (2014) Tetrahydroxanthene-1,3(2H)-dione Derivatives fromUvaria valderramensis. Journal of Natural Products 77 (12), pp. 2711-2715. Fulltext not available.

Endlich, Nicole , Simon, Ole, Goepferich, Achim , Wegner, Henny, Moeller, Marcus J., Rumpel, Elisabeth, Kotb, Ahmed and Endlich, Karlhans (2014) Two-Photon Microscopy Reveals Stationary Podocytes in Living Zebrafish Larvae. Journal of the American Society of Nephrology 25 (4), pp. 681-686. Fulltext not available.

Liebchen, Uwe, Kratzer, Alexander, Wicha, Sebastian G., Kees, Frieder, Kloft, Charlotte and Kees, Martin G. (2014) Unbound fraction of ertapenem in intensive care unit patients. Journal of Antimicrobial Chemotherapy 69 (11), pp. 3108-3111. Fulltext not available.

Kees, Martin G., Wicha, Sebastian G., Seefeld, Astrid, Kees, Frieder and Kloft, Charlotte (2014) Unbound fraction of vancomycin in intensive care unit patients. The Journal of Clinical Pharmacology 54 (3), pp. 318-323. Fulltext not available.

Schickaneder, Helmut, Buschauer, Armin, Bernhardt, Günther, Schickaneder, Christian, Limmert, Michael, Huber, Stefan, Lubbe, Mathias and Hofmeier, Harald (2013) Esters of bendamustine and related compounds, and medical use thereof. Fulltext not available.

Brunner, Elisabeth (2013) Einsatz von Everolimus zur Prävention der chronischen Abstoßung nach orthotoper unilateraler Lungentransplantation in der Ratte. PhD, Universität Regensburg.

Schmidt, Sebastian (2013) Phytochemische und pharmakologische in vitro Untersuchungen zu Hypericum empetrifolium WILLD. PhD, Universität Regensburg.

Loth, Tina, Hennig, Robert, Kascholke, Christian, Hötzel, Rudi and Hacker, Michael (2013) Reactive and stimuli-responsive maleic anhydride containing macromers–multi-functional cross-linkers and building blocks for hydrogel fabrication. Reactive and Functional Polymers 73 (11), pp. 1480-1492. Fulltext not available.

Sadek, Bassem, Alisch, Rudi, Buschauer, Armin and Elz, Sigurd (2013) Synthesis and dual histamine H1 and H2 receptor antagonist activity of cyanoguanidine derivatives. Molecules 18 (11), pp. 14186-14202.

Dove, Stefan and Buschauer, Armin (2013) G-Protein-gekoppelte Rezeptoren: „Sinnesorgane“ der Zellen. Blick in die Wissenschaft 22 (28), pp. 3-9. Fulltext not available.

Schreeb, Annemarie, Łażewska, Dorota, Dove, Stefan, Buschauer, Armin, Kieć-Kononiwcz, Katarzyna and Stark, Holger (2013) 2. Histamine H4 receptor ligands. In: Stark, Holger, (ed.) Histamine H4 receptor: a novel drug target for immunoregulation and inflammation. Versita, London, pp. 21-62. ISBN 9788376560564. Fulltext not available.

Stöckl, Sabine (2013) Der Einfluss von Sox9 auf Zellvitalität und Differenzierungspotential von adulten mesenchymalen Stammzellen. PhD, Universität Regensburg.

Keller, Max, Kaske, Melanie, Holzammer, Tobias, Bernhardt, Günther and Buschauer, Armin (2013) Dimeric argininamide-type neuropeptide Y receptor antagonists: chiral discrimination between Y1 and Y4 receptors. Bioorganic and Medicinal Chemistry 21 (21), pp. 6303-6322. Fulltext not available.

Weisser, Roland (2013) Planung einer Studie zur Etablierung des therapeutischen Referenzbereichs der Wirkstoffkonzentration eines Antidementivums. PhD, Universität Regensburg.

Berlicki, Lukasz , Kaske, Melanie, Gutierrez-Abad, Raquel, Bernhardt, Günther, Illa, Ona , Ortuño, Rosa, Cabrele, Chiara , Buschauer, Armin and Reiser, Oliver (2013) Replacement of Thr32 and Gln34 in the C-terminal neuropeptide Y fragment 25-36 by cis-cyclobutane- and cis-cyclopentane β-amino acids shifts selectivity toward the Y4 receptor. Journal of Medicinal Chemistry 56 (21), pp. 8422-8431. Fulltext not available.

Nordemann, Uwe, Wifling, David , Schnell, David, Bernhardt, Günther, Stark, Holger , Seifert, Roland and Buschauer, Armin (2013) Luciferase reporter gene assay on human, murine and rat histamine H4 receptor orthologs: correlations and discrepancies between distal and proximal readouts. PLoS One 8 (9), e73961.

Bauer, Stefanie, Ochoa Puentes, Cristian, Sun, Qiu, Bause, Manuel, Bernhardt, Günther, König, Burkhard and Buschauer, Armin (2013) Quinoline carboxamide-type ABCG2 modulators: Indole and quinoline moieties as anilide replacements. ChemMedChem 8 (11), pp. 1773-1778. Fulltext not available.

Holzammer, Tobias (2013) Homology modeling, molecular dynamics simulations and site-directed mutagenesis of histamine H2 receptors. PhD, Universität Regensburg.

Kirchhof, Susanne, Brandl, Ferdinand, Hammer, Nadine and Göpferich, Achim (2013) Investigation of the Diels–Alder reaction as a cross-linking mechanism for degradable poly(ethylene glycol) based hydrogels. Journal of Materials Chemistry B 1 (37), pp. 4855-4864. Fulltext not available.

Kaske, Melanie (2013) In search for potent and selective NPY Y4 receptor ligands: acylguanidines, argininamides and peptide analogs. PhD, Universität Regensburg.

Brunskole Hummel, Irena, Kälble, Solveig, Burhenne, Heike, Reinartz, Michael T., Schwede, Frank, Buschauer, Armin and Seifert, Roland (2013) Dissociations in the effects of beta2-adrenergic receptor agonists on cAMP formation and superoxide production in human neutrophils: Support for the concept of functional selectivity. PLoS One 8 (5), e64556.

Zölls, Sarah, Gregoritza, Manuel, Tantipolphan, Ruedeeporn, Wiggenhorn, Michael, Winter, Gerhard, Friess, Wolfgang and Hawe, Andrea (2013) How Subvisible Particles Become Invisible - Relevance of the Refractive Index for Protein Particle Analysis. Journal of Pharmaceutical Sciences 102 (5), pp. 1434-1446. Fulltext not available.

Kees, Martin Georg, Schaeftlein, André, Haeberle, Helene Anna, Kees, Frieder K., Kloft, Charlotte and Heininger, Alexandra (2013) Population pharmacokinetics and pharmacodynamic evaluation of intravenous and enteral moxifloxacin in surgical intensive care unit patients. The Journal of antimicrobial chemotherapy. Fulltext not available.

Ochoa-Puentes, Cristian, Bauer, Stefanie, Kühnle, Matthias, Bernhardt, Günther, Buschauer, Armin and König, Burkhard (2013) Benzanilide – Biphenyl Replacement: A Bioisosteric Approach to Quinoline Carboxamide-type ABCG2 Modulators. ACS Medicinal Chemistry Letters 4 (4), pp. 393-396. Fulltext not available.

Pluym, Nikola , Baumeister, Paul, Keller, Max, Bernhardt, Günther and Buschauer, Armin (2013) [3H]UR-PLN196: A Selective Nonpeptide Radioligand and Insurmountable Antagonist for the Neuropeptide Y Y2 Receptor. ChemMedChem 8 (4), pp. 587-593. Fulltext not available.

Miller, Tobias (2013) Polymeric micelles for solubilization and targeting of hydrophobic drugs. PhD, Universität Regensburg.

Seifert, Roland, Strasser, Andrea, Schneider, Erich H., Neumann, Detlef, Dove, Stefan and Buschauer, Armin (2013) Molecular and cellular analysis of human histamine receptor subtypes. Trends in Pharmacological Sciences 34 (1), pp. 33-58. Fulltext not available.

Strasser, Andrea, Wittmann, Hans-Joachim, Buschauer, Armin, Schneider, Erich H. and Seifert, Roland (2013) Species-dependent activities of GPCR ligands: Lessons from histamine receptor orthologs. Trends in Pharmacological Sciences 34 (1), pp. 13-32. Fulltext not available.

Chen, Wen, Oberwinkler, Heike, Werner, Franziska, Gaßner, Birgit, Nakagawa, Hitoshi, Feil, Robert , Hofmann, Franz, Schlossmann, Jens , Dietrich, Alexander , Gudermann, Thomas, Nishida, Motohiro , Del Galdo, Sabrina, Wieland, Thomas and Kuhn, Michaela (2013) Atrial Natriuretic Peptide–Mediated Inhibition of Microcirculatory Endothelial Ca 2+ and Permeability Response to Histamine Involves cGMP-Dependent Protein Kinase I and TRPC6 Channels. Arteriosclerosis, Thrombosis, and Vascular Biology 33 (9), pp. 2121-2129. Fulltext not available.

Klein, Regina, Müller, Eva, Kraus, Birgit, Brunner, Gabi, Estrine, Boris , Touraud, Didier, Heilmann, Jörg, Kellermeier, Matthias and Kunz, Werner (2013) Biodegradability and cytotoxicity on human cell lines of choline soaps: effects of chain length and cation. RSC Advances 3 (45), pp. 23347-23354. Fulltext not available.

Scherübl, Rosmarie, Manns, Detlef, Heilmann, Jörg and Franz, Gerhard (2013) Comparison of HPLC Versus HPTLC-Densitometry for the Quantification of Chromone Glucosides in Saposhnikoviae divaricatae Radix. Chromatographia 76 (21-22), pp. 1537-1543. Fulltext not available.

DEMİRCİ, FATİH, YEŞİLADA, ERDEM , BAŞER, KEMAL HÜSNÜ CAN, FRANZ, GERHARD , DEMİRCİ, BETÜL and GÜRBÜZ, İLHAN (2013) Comparison of the volatiles of Daphne pontica L. and D. oleoides Schreber subsp. oleoides isolated by hydro- and microdistillation methods. Turkish Journal of Biology. Fulltext not available.

Luschmann, Christoph, Tessmar, Joerg , Schoeberl, Simon, Framme, Carsten, Luschmann, Karl and Goepferich, Achim (2013) Developing an in situ nanosuspension: A novel approach towards the efficient administration of poorly soluble drugs at the anterior eye. European Journal of Pharmaceutical Sciences 50 (3-4), pp. 385-392. Fulltext not available.

Tang, Chih-Hsin, Brunskole Hummel, Irena, Reinartz, Michael T., Kälble, Solveig, Burhenne, Heike, Schwede, Frank, Buschauer, Armin and Seifert, Roland (2013) Dissociations in the Effects of β2-Adrenergic Receptor Agonists on cAMP Formation and Superoxide Production in Human Neutrophils: Support for the Concept of Functional Selectivity. PLoS ONE 8 (5), e64556. Fulltext not available.

Miller, Tobias, van Colen, G., Sander, B., Golas, M., Uezguen, Senta, Weigandt, Markus and Goepferich, Achim (2013) Drug Loading of Polymerics Micelles. Pharmaceutical Research 30 (2), pp. 484-595. Fulltext not available.

Dietrich, P., Moleda, Lukas, Kees, Frieder K., Müller, M., Straub, R. H. , Hellerbrand, C. and Wiest, R. (2013) Dysbalance in sympathetic neurotransmitter release and action in cirrhotic rats: impact of exogenous neuropeptide Y. Journal of hepatology 58 (2), pp. 254-261. Fulltext not available.

Scheeren, Thomas W. L., Wiesenack, Christoph, Gerlach, Herwig and Marx, Gernot (2013) Goal-directed intraoperative fluid therapy guided by stroke volume and its variation in high-risk surgical patients: a prospective randomized multicentre study. Journal of Clinical Monitoring and Computing 27 (3), pp. 225-233. Fulltext not available.

Ferstl, Matthias, Drechsler, Markus , Rachel, Reinhard, Rischer, M., Engel, J., Backofen, Michael and Goepferich, Achim (2013) Impact of Polyelectrolyte Structure on the Shape of Nanoassemblies with Cationic Peptides. European Journal of Pharmaceutical Sciences 102, pp. 2599-2607. Fulltext not available.

Zenger, Katharina, Chen, Xinyu, Decker, Michael and Kraus, Birgit (2013) In-vitro stability and metabolism of a tacrine–silibinin codrug. Journal of Pharmacy and Pharmacology 65 (12), pp. 1765-1772. Fulltext not available.

Seifert, Roland and Dove, Stefan (2013) Inhibitors of Bacillus anthracis edema factor. Pharmacology & Therapeutics 140 (2), pp. 200-212. Fulltext not available.

Mueller, M., Blunk, Torsten, Appel, Bernhard, Maschke, Angelika, Goepferich, Achim and Zellner, J. (2013) Insulin is essential for in vitro chondrogenesis of mesenchymal progenitor cells and influences chondrogenesis in a dose-dependent manner. International orthopaedics 37 (1), pp. 153-158. Fulltext not available.

Mueller, Michael B., Blunk, Torsten, Appel, Bernhard, Maschke, Angelika, Goepferich, Achim , Zellner, Johannes , Englert, Carsten , Prantl, Lukas, Kujat, Richard, Nerlich, Michael and Angele, Peter (2013) Insulin is essential for in vitro chondrogenesis of mesenchymal progenitor cells and influences chondrogenesis in a dose-dependent manner. International Orthopaedics 37 (1), pp. 153-158. Fulltext not available.

Kirchhof, Susanne, Brandl, Ferdinand P., Hammer, Nadine and Goepferich, Achim M. (2013) Investigation of the Diels–Alder reaction as a cross-linking mechanism for degradable poly(ethylene glycol) based hydrogels. Journal of Materials Chemistry B 1 (37), p. 4855. Fulltext not available.

Wurster, Eva-Christina, Elbakry, Asmaa, Goepferich, Achim and Breunig, Miriam (2013) Layer-by-layer assembled gold nanoparticles for the delivery of nucleic acids. In: Nanotechnology for Nucleic Acid Delivery : Methods and Protocols. Methods in Molecular Biology, 948. Humana Press; Springer, Totowa, NJ, pp. 171-182. ISBN 978-1-62703-139-4 (print), 978-1-627-03140-0 (online). Fulltext not available.

Pollinger, Klaus, Hennig, Robert, Ohlmann, Andreas, Fuchshofer, Rudolf , Wenzel, Rebecca, Breunig, Miriam , Tessmar, Joerg , Tamm, Ernst R. and Goepferich, Achim (2013) Ligand-functionalized nanoparticles target endothelial cells in retinal capillaries after systemic application. Proceedings of the National Academy of Sciences of the United States of America (PNAS) 110 (15), pp. 6115-6120. Fulltext not available.

Strasser, Andrea and Wittmann, Hans-Joachim (2013) Modelling of GPCRs - A Practical Handbook. Springer. Fulltext not available.

Oberprieler, Christoph, Dietz, Lena, Harlander, Christine and Heilmann, Jörg (2013) Molecular and phytochemical evidence for the taxonomic integrity of Salix alba, S. fragilis, and their hybrid S. × rubens (Salicaceae) in mixed stands in SE Germany. Plant Systematics and Evolution 299 (6), pp. 1107-1118. Fulltext not available.

Straßer, Andrea and Wittmann, Hans-Joachim (2013) Molecular modeling studies give hint for the existence of a symmetric hβ2R-Gαβγ-homodimer. Journal of Molecular Modeling 19 (10), pp. 4443-4457. Fulltext not available.

Strasser, Andrea and Wittmann, Hans-Joachim (2013) Molecular modelling studies give hint for the existence of a symmetric hb2R-Gabg-homodimer. J Mol Model 19, pp. 4443-4457. Fulltext not available.

Hozsa, Constantin, Breunig, Miriam and Goepferich, Achim (2013) Monitoring the Degradation of Reduction-Sensitive Gene Carriers with Fluorescence Spectroscopy and Flow Cytometry. Methods in Molecular Biology 991, pp. 171-184. Fulltext not available.

Luschmann, Christoph, Herrmann, W., Strauss, Olaf, Luschmann, Karl and Goepferich, Achim (2013) Ocular delivery systems for poorly soluble drugs: An in-vivo evaluation. International Journal of Pharmaceutics 455 (1-2), pp. 331-337. Fulltext not available.

Luschmann, C., Herrmann, W., Strauß, O., Luschmann, K. and Goepferich, A. (2013) Ocular delivery systems for poorly soluble drugs: An in-vivo evaluation. International Journal of Pharmaceutics 455 (1-2), pp. 331-337. Fulltext not available.

Schweizer, Daniel, Vostiar, Igor, Heier, Annabelle, Serno, Tim, Schoenhammer, Karin, Jahn, Michael, Jones, Stewart, Piequet, Aline, Beerli, Christian, Gram, Hermann and Goepferich, Achim (2013) Pharmacokinetics, biocompatibility and bioavailability of a controlled release monoclonal antibody formulation. Journal of Controlled Release 172 (3), pp. 975-982. Fulltext not available.

Miller, Tobias, Breyer, S., van Colen, G., Mier, W., Haberkorn, U., Geissler, S., Voss, S., Weigandt, Markus and Goepferich, Achim (2013) Premature drug release of polymeric micelles and its effects on tumor targeting. International Journal of Pharmaceutics 445 (1-2), pp. 117-124. Fulltext not available.

Schweizer, Daniel, Schoenhammer, K., Jahn, M. and Goepferich, Achim (2013) Protein-​Polyanion Interactions for the Controlled Release of Monoclonal Antibodies. Biomacromolecules 14 (1), pp. 75-83. Fulltext not available.

Holzhauser, C., Liebl, Renate, Goepferich, Achim , Wagenknecht, Hans-Achim and Breunig, Miriam (2013) RNA “Traffic Lights”: An Analytical Tool to Monitor siRNA Integrity. ACS chemical biology 8, pp. 890-894. Fulltext not available.

Nordemann, Uwe (2013) Radioligand binding and reporter gene assays for histamine H3 and H4 receptor species orthologs. PhD, Universität Regensburg.

Barbič, M., Willer, E.A., Rothenhöfer, M., Heilmann, J., Fürst, R. and Jürgenliemk, G. (2013) Spirostanol saponins and esculin from Rusci rhizoma reduce the thrombin-induced hyperpermeability of endothelial cells. Phytochemistry 90, pp. 106-113. Fulltext not available.

Schinner, E., Schramm, A., Kees, F., Hofmann, F. and Schlossmann, Jens (2013) Suppression of kidney fibrosis by cGMP-dependent protein Kinase Ia. Kidney International. (In Press) Fulltext not available.

Würtenberger, Irene, Angermaier, Bernhard, Kircher, Brigitte and Gust, Ronald (2013) Synthesis and In Vitro Pharmacological Behavior of Platinum(II) Complexes Containing 1,2-Diamino-1-(4-fluorophenyl)-2-alkanol Ligands. Journal of Medicinal Chemistry 56 (20), pp. 7951-7964. Fulltext not available.

Bodensteiner, Julian, Baumeister, Paul, Geyer, Roland, Buschauer, Armin and Reiser, Oliver (2013) Synthesis and pharmacological characterization of new tetrahydrofuran based compounds as conformationally constrained histamine receptor ligands. Organic & biomolecular chemistry 11 (24), pp. 4040-4055.

Susanne Hopf, , Monika Bumel, , Michael Gruber, , Thomas Bein, , Marcus Creutzenberg, , Bernhard Graf, and Michael Pawlik, (2013) The Effect of Perchlorate Medication on Point-of-Care Testing. Clinical Laboratory 59 (01+02/). Fulltext not available.

Göpferich, Achim (2013) To pause a moment. European Journal of Pharmaceutics and Biopharmaceutics 85 (3), p. 328. Fulltext not available.

Dorn, Christoph , Massinger, Sabine, Wuzik, Andreas, Heilmann, Jörg and Hellerbrand, Claus (2013) Xanthohumol suppresses inflammatory response to warm ischemia–reperfusion induced liver injury. Experimental and Molecular Pathology 94 (1), pp. 10-16. Fulltext not available.

Wolfertstetter, Stefanie, Huettner, Johannes Philip and Schlossmann, Jens (2013) cGMP-dependent Protein Kinase Inhibitors in Health and Disease. Pharmaceuticals 6, pp. 269-286.

Ertel, Miriam, Bernhardt, Günther, Nink, Jörg and Buschauer, Armin (2012) Novel prodrugs of (1S,9S)-9-[[(1S)-1-carboxy-3-phenylpropyl]amino]octahydro-10-oxo-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid and their use in transdermal therapeutic systems. Fulltext not available.

Memminger, Martin, Keller, Max, Lopuch, Miroslaw, Pop, Nathalie, Bernhardt, Günther, von Angerer, Erwin and Buschauer, Armin (2012) The Neuropeptide Y Y1 receptor: a diagnostic marker? Expression in MCF-7 breast cancer cells is down-regulated by antiestrogens in vitro and in xenografts. PLoS ONE 7 (12), e51032.

Löber, Stefan, Hübner, Harald, Buschauer, Armin, Sanna, Fabrizio , Argiolas, Antonio, Melis, Maria Rosaria and Gmeiner, Peter (2012) Novel azulene derivatives for the treatment of erectile dysfunction. Bioorganic & medicinal chemistry letters 22 (23), pp. 7151-7154. Fulltext not available.

Saugspier, Michael Sebastian (2012) Analysis of the anti-fibrotic effects of hop bitter acids on hepatic stellate cells and their anti-tumorigenic effects on hepatocellular carcinoma cells. PhD, Universität Regensburg.

Rothenhöfer, Martin, Scherübl, Rosmarie, Bernhardt, Günther, Heilmann, Jörg and Buschauer, Armin (2012) Qualitative and quantitative analysis of hyaluronan oligosaccharides with high performance thin layer chromatography using reagent-free derivatization on amino-modified silica and electrospray ionization-quadrupole time-of-flight mass spectrometry coupling on normal phase. Journal of chromatography. A 1248, pp. 169-77. Fulltext not available.

Ertel, Miriam (2012) Ambivalence of drug metabolism: Exploration of cilazapril and candesartan prodrugs for transdermal delivery and search for toxic reactive intermediates of N(G)-acylated hetarylpropylguanidines. PhD, Universität Regensburg.

Hild, Wolfgang (2012) Cellular nanoparticle delivery by G-protein coupled receptors. PhD, Universität Regensburg.

Reher, Till M., Neumann, Detlef, Buschauer, Armin and Seifert, Roland (2012) Incomplete activation of human eosinophils via the histamine H(4)-receptor: Evidence for ligand-specific receptor conformations. Biochemical Pharmacology 84 (2), pp. 192-203. Fulltext not available.

Seifert, Roland and Dove, Stefan (2012) 3/14. Molecular analysis of agonist stereoisomers at β2-adrenoceptors. In: Jozwiak, Krzysztof and Lough, W. John and Wainer, Irving W., (eds.) Drug stereochemistry : Analytical methods and pharmacology. 3. ed. Informa Healthcare, New York, pp. 274-293. ISBN 9781420092387. Fulltext not available.

Deml, Karl-Friedrich (2012) Interaktionen von Histamin H1-Rezeptoragonisten und
–antagonisten mit dem humanen Histamin H4-Rezeptor. PhD, Universität Regensburg.

Schlossmann, Jens and Schinner, E. (2012) cGMP becomes a drug target. Naunyn Schmiedeberg´s Archives of Pharmacology 385 (3), pp. 243-252.

Birnkammer, Tobias, Spickenreither, Anja, Brunskole, Irena, Lopuch, Miroslaw, Kagermeier, Nicole, Bernhardt, Günther, Dove, Stefan, Seifert, Roland, Elz, Sigurd and Buschauer, Armin (2012) The bivalent ligand approach leads to highly potent and selective acylguanidine-type histamine H2 receptor agonists. Journal of Medicinal Chemistry 55 (3), pp. 1147-1160. Fulltext not available.

Dorn, Christoph , Heilmann, Jörg and Hellerbrand, Claus (2012) Protective effect of xanthohumol on toxin-induced liver inflammation and fibrosis. International Journal of Clinical and Experimental Pathology 5 (1), pp. 29-36.

Bauhuber, Sonja, Liebl, Renate, Tomasetti, Luise, Rachel, Reinhard, Goepferich, Achim and Breunig, Miriam (2012) A library of strictly linear poly(ethylene glycol)-poly(ethylene imine) diblock coploymers to perform structure-function relationship on non-viral gene carriers. Journal of Controlled Release 162, pp. 446-455. Fulltext not available.

Bubik, Martin F., Willer, Elisabeth A., Bihari, Peter, Jürgenliemk, Guido, Ammer, Hermann , Krombach, Fritz, Zahler, Stefan, Vollmar, Angelika M. and Fürst, Robert (2012) A novel approach to prevent endothelial hyperpermeability: The Crataegus extract WS® 1442 targets the cAMP/Rap1 pathway. Journal of Molecular and Cellular Cardiology 52 (1), pp. 196-205. Fulltext not available.

Schädlich, Andreas, Hoffmann, Stefan, Mueller, Thomas, Caysa, Henrike, Rose, Cornelia, Göpferich, Achim , Li, Jun, Kuntsche, Judith and Mäder, Karsten (2012) Accumulation of nanocarriers in the ovary: A neglected toxicity risk? Journal of Controlled Release 160 (1), pp. 105-112. Fulltext not available.

Romanski, Steffen, Kraus, Birgit, Guttentag, Miguel, Schlundt, Waldemar, Rücker, Hannelore, Adler, Andreas, Neudörfl, Jörg-Martin, Alberto, Roger, Amslinger, Sabine and Schmalz, Hans-Günther (2012) Acyloxybutadiene tricarbonyl iron complexes as enzyme-triggered CO-releasing molecules (ET-CORMs): a structure–activity relationship study. Dalton Transactions 41 (45), p. 13862. Fulltext not available.

Miller, Tobias, Hiller, Alexandra, Uezguen, Senta, Weigandt, Markus and Goepferich, Achim (2012) Analysis of Immediate Stress Mechanisms upon Injection of Polymeric Micelles and Related Colloidal Drug Carriers. Biomacromolecules 13 (6), pp. 1707-1718. Fulltext not available.

Scherübl, R, Beggs, A, Franz, G, Heilmann, J and Manns, D (2012) Analysis of chromone glycosides in saposhnikovia divaricata for the establishment of a monograph of the german pharmacopoeia. Planta Medica 78 (11). Fulltext not available.

Göttle, Martin, Dove, Stefan and Seifert, Roland (2012) Bacillus anthracis edema factor substrate specificity: evidence for new modes of action. Toxins 4 (7), pp. 505-535.

Beckers, Thomas, Mahboobi, Siavosh, Sellmer, Andreas, Winkler, Matthias, Eichhorn, Emerich, Pongratz, Herwig, Maier, Thomas, Ciossek, Thomas, Baer, Thomas, Kelter, Gerhard, Fiebig, Heinz-Herbert and Schmidt, Mathias (2012) Chimerically designed HDAC- and tyrosine kinase inhibitors. A series of erlotinib hybrids as dual-selective inhibitors of EGFR, HER2 and histone deacetylases. MedChemComm 3 (7), p. 829. Fulltext not available.

Freischmidt, A., Jürgenliemk, G., Kraus, B., Okpanyi, S.N., Müller, J., Kelber, O. , Weiser, D. and Heilmann, J. (2012) Contribution of flavonoids and catechol to the reduction of ICAM-1 expression in endothelial cells by a standardised Willow bark extract. Phytomedicine 19 (3-4), pp. 245-252. Fulltext not available.

Vo, Hau T., Nguyen, Ngoc-Tuyet T., Nguyen, Hieu T., Do, Khoa Q. , Connolly, Joseph D., Maas, Gerhard, Heilmann, Jörg, Werz, Udo R., Pham, Hung D. and Nguyen, Lien-Hoa D. (2012) Cytotoxic tetraoxygenated xanthones from the bark of Garcinia schomburgkiana. Phytochemistry Letters 5 (3), pp. 553-557. Fulltext not available.

Reher, Till M., Brunskole, Irena, Neumann, Detlef and Seifert, Roland (2012) Evidence for ligand-specific conformations of the histamine H2-receptor in human eosinophils and neutrophils. Biochemical Pharmacology 84 (9), pp. 1174-1185. Fulltext not available.

Grundmann, Marco, Rothenhöfer, M., Bernhardt, Günther, Buschauer, Armin and Matysik, Frank-Michael (2012) Fast counter-electroosmotic capillary electrophoresis-time-of-flight mass spectrometry of hyaluronan oligosaccharides. Analytical and Bioanalytical Chemistry : Anal. Bioanal. Chem. 402, pp. 2617-2623. Fulltext not available.

Henke, Matthias, Baumer, Julia, Blunk, Torsten and Tessmar, Joerg (2012) Foamed oligo(poly(ethylene glycol)fumarate) hydrogels as versatile prefabricated scaffolds for tissue engineering. Journal of Tissue Engineering and Regenerative Medicine 8 (3), pp. 248-252. Fulltext not available.

Posavec, Damir, Zabel, Manfred, Bogner, Udo, Bernhardt, Günther and Knör, Günther (2012) Functionalized derivatives of 1,4-dimethylnaphthalene as precursors for biomedical applications: synthesis, structures, spectroscopy and photochemical activation in the presence of dioxygen. Organic & biomolecular chemistry 10 (35), pp. 7062-7069.

Zayed, Gamal M. S. and Tessmar, Joerg K. V. (2012) Heterobifunctional Poly(ethylene glycol) Derivatives for the Surface Modification of Gold Nanoparticles Toward Bone Mineral Targeting. Macromolecular Bioscience 12 (8), pp. 1124-1136. Fulltext not available.

Tavčar, Eva, Barbič, Matej, Heilmann, Jörg and Kreft, Samo (2012) High levels of cycloartenol derivatives from Euphorbia acanthothamnos. Biochemical Systematics and Ecology 44, pp. 83-85. Fulltext not available.

Saugspier, Michael, Dorn, Christoph , Czech, Barbara, Gehrig, Manfred, Heilmann, Jörg and Hellerbrand, Claus (2012) Hop bitter acids inhibit tumorigenicity of hepatocellular carcinoma cells in vitro. Oncology Reports 28 (4), pp. 1423-1428. Fulltext not available.

Reher, Till M., Neumann, Detlef , Buschauer, Armin and Seifert, Roland (2012) Incomplete activation of human eosinophils via the histamine H4-receptor: Evidence for ligand-specific receptor conformations. Biochemical Pharmacology 84 (2), pp. 192-203. Fulltext not available.

Taha, Hesham, Dove, Stefan, Geduhn, Jens, König, Burkhard , Shen, Yuequan , Tang, Wei-Jen and Seifert, Roland (2012) Inhibition of the adenylyl cyclase toxin, edema factor, from Bacillus anthracis by a series of 18 monoand bis-(M)ANT-substituted nucleoside 5′-triphosphates. Naunyn-Schmiedeberg's Archives of Pharmacology (385), pp. 57-68. Fulltext not available.

Appl, Heidrun, Holzammer, Tobias, Dove, Stefan, Haen, Ekkehard, Strasser, Andrea and Seifert, Roland (2012) Interactions of recombinant human histamine H₁R, H₂R, H₃R, and H₄R receptors with 34 antidepressants and antipsychotics. Naunyn-Schmiedeberg's archives of pharmacology 385 (2), pp. 145-170. Fulltext not available.

Pollinger, Klaus, Hennig, Robert, Breunig, Miriam , Teßmar, Jörg , Ohlmann, Andreas , Tamm, Ernst R. , Witzgall, Ralph and Goepferich, Achim (2012) Kidney Podocytes as Specific Targets for cyclo(RGDfC)-Modified Nanoparticles. Small 8, pp. 3368-3375. Fulltext not available.

Win, Thida, Htwe, Thant Thant, Shwe, Htay Htay and Heilmann, Jörg (2012) Lavandulyl Flavanones from the Stems of Hypericum calycinum L. Chemistry & Biodiversity 9 (6), pp. 1198-1204. Fulltext not available.

Elbakry, Asmaa Mohamed, Wurster, Eva-Christina, Zaky, Alaa, Liebl, Renate, Schindler, Edith, Bauer-Kreisel, Petra, Blunk, Torsten, Rachel, Reinhard, Goepferich, Achim and Breunig, Miriam (2012) Layer-by-Layer Coated Gold Nanoparticles: Size-Dependent Delivery of DNA into Cells. Small 8 (24), pp. 3847-3856. Fulltext not available.

Heller, Anne, Fischer, Lorenz H., Wolfbeis, Otto S. and Göpferich, Achim (2012) Long time monitoring of the respiratory activity of isolated mitochondria. Experimental Cell Research 318 (14), pp. 1667-1672. Fulltext not available.

Decker, Michael and Holzgrabe, Ulrike (2012) M1 muscarinic cetylcholine receptor allosteric modulators as potential therapeutic opportunities for treating Alzheimer's disease. MedChemComm 3 (7), p. 752. Fulltext not available.

Darras, Fouad H., Kling, Beata, Heilmann, Jörg and Decker, Michael (2012) Neuroprotective Tri- and Tetracyclic BChE Inhibitors Releasing Reversible Inhibitors upon Carbamate Transfer. ACS Medicinal Chemistry Letters 3 (11), pp. 914-919. Fulltext not available.

Barbič, Matej, Schmidt, Thomas J. and Jürgenliemk, Guido (2012) Novel Phenyl‐1‐benzoxepinols from Butcher's Broom (Rusci rhizoma). Chemistry & Biodiversity 9 (6), pp. 1077-1083. Fulltext not available.

Beckers, Thomas, Sellmer, Andreas, Eichhorn, Emerich, Pongratz, Herwig, Schächtele, Christoph, Totzke, Frank, Kelter, Gerhard, Krumbach, Rebekka, Fiebig, Heinz-Herbert, Böhmer, Frank-D. and Mahboobi, Siavosh (2012) Novel inhibitors of epidermal growth factor receptor: (4-(Arylamino)-7H-pyrrolo[2,3-d]pyrimidin-6-yl)(1H-indol-2-yl)methanones and (1H-indol-2-yl)(4-(phenylamino)thieno[2,3-d]pyrimidin-6-yl)methanones. Bioorganic & Medicinal Chemistry 20 (1), pp. 125-136. Fulltext not available.

Ulrich-Merzenich, G., Kelber, O. , Koptina, A. , Freischmidt, A., Heilmann, J., Müller, J., Zeitler, H., Seidel, M.F., Ludwig, M., Heinrich, E.U. and Winterhoff, H. (2012) Novel neurological and immunological targets for salicylate-based phytopharmaceuticals and for the anti-depressant imipramine. Phytomedicine 19 (10), pp. 930-939. Fulltext not available.

Kees, Martin G., Steinke, T., Moritz, S., Rupprecht, K., Paulus, E. M., Kees, Frieder K., Bucher, M. and Faerber, L. (2012) Omeprazole impairs the absorption of mycophenolate mofetil but not of enteric-coated mycophenolate sodium in healthy volunteers. Journal of clinical pharmacology 52 (8), pp. 1265-1272. Fulltext not available.

Toth, I., Neumann, I.D. and Slattery, D.A. (2012) P.2.001 Differential effects of central oxytocin on social versus cued fear. European Neuropsychopharmacology 22, S32-S33. Fulltext not available.

Justinger, Christoph, Schilling, Martin K., Kees, Martin G., Kauffels, Anne, Hirschmann, Katrin, Kopp, Berit, Kees, Frieder K. and Kollmar, Otto (2012) Penetration of moxifloxacin into liver tissue. International journal of antimicrobial agents 39 (6), pp. 505-509. Fulltext not available.

Schmidt, Sebastian, Jürgenliemk, Guido, Skaltsa, Helen and Heilmann, Jörg (2012) Phloroglucinol derivatives from Hypericum empetrifolium with antiproliferative activity on endothelial cells. Phytochemistry 77, pp. 218-225. Fulltext not available.

Nguyen, Le-Thu T., Nguyen, Hieu T., Barbič, Matej, Brunner, Gabi, Heilmann, Jörg, Pham, Hung D., Nguyen, Duc M. and Nguyen, Lien-Hoa D. (2012) Polyisoprenylated acylphloroglucinols and a polyisoprenylated tetracyclic xanthone from the bark of Calophyllum thorelii. Tetrahedron Letters 53 (34), pp. 4487-4493. Fulltext not available.

Ulrich-Merzenich, G., Koptina, A. , Kelber, O. , Freischmidt, A., Heilmann, J., Müller, J., Sadeghlar, F., Zeitler, H. and Wagner, H. (2012) Prediction of adverse events by in vivo gene expression profiling exemplified for phytopharmaceuticals containing salicylates and the antidepressant imipramine. Phytomedicine 19 (3-4), pp. 322-329. Fulltext not available.

Slattery, D.A., Naik, R., Yen, Y.C., Czibere, L., Finger, B., Mathé, A.A., Wegener, G., Landgraf, R. and Neumann, I.D. (2012) S.02.02 Neuropeptide S and anxiety. European Neuropsychopharmacology 22, S31-S32. Fulltext not available.

Bernat, Viachaslau , Heinrich, Markus , Baumeister, Paul, Buschauer, Armin and Tschammer, Nuska (2012) Synthesis and application of the first radioligand targeting the allosteric binding pocket of chemokine receptor CXCR3. ChemMedChem 7 (8), pp. 1481-1489. Fulltext not available.

Chen, Xinyu, Zenger, Katharina, Lupp, Amelie, Kling, Beata, Heilmann, Jörg, Fleck, Christian, Kraus, Birgit and Decker, Michael (2012) Tacrine-Silibinin Codrug Shows Neuro- and Hepatoprotective Effects in Vitro and Pro-Cognitive and Hepatoprotective Effects in Vivo. Journal of Medicinal Chemistry 55 (11), pp. 5231-5242. Fulltext not available.

Heller, Anne, Brockhoff, Gero and Goepferich, Achim (2012) Targeting drugs to mitochondria. European Journal of Pharmaceutics and Biopharmaceutics 82, pp. 1-18. Fulltext not available.

Schmidt, Jennifer, Riechers, Alexander, Stoll, Raphael, Amann, Thomas, Fink, Florian, Spruss, Thilo, Gronwald, Wolfram, König, Burkhard , Hellerbrand, Claus and Bosserhoff, Anja Katrin (2012) Targeting melanoma metastasis and immunosuppression with a new mode of melanoma inhibitory activity (MIA) protein inhibition. PloS ONE 7 (5), e37941.

Koptina, A, Kelber, O, Zeitler, H, Abdel-Aziz, H, Ludwig, M, Heilmann, J, Freischmidt, A, Wagner, H and Ulrich-Merzenich, G (2012) Targeting of LOX-1 by willow bark, its etoh-fraction and by the antidepressant imipramine. Planta Medica 78 (11). Fulltext not available.

Seifert, S, Kiesselbach, C, Kopeinig, B, Bauer, R, Gessner, A and Haunschild, J (2012) The Novel Sinupret® dry extract BNO 1011 inhibits paw oedema development in vivo and inflammatory mediator release in vitro. Planta Medica 78 (11). Fulltext not available.

Seifert, Roland and Dove, Stefan (2012) Towards selective inhibitors of adenylyl cyclase toxin from Bordetella pertussis. Trends in microbiology 20 (7), pp. 343-351. Fulltext not available.

Kaftan, Holger, Goepferich, Achim, Kaftan, Silke and Hosemann, Werner (2012) Two different techniques to facilitate reconstruction of the long incus process with bone cement: a feasibility study in human cadaveric temporal bones. European Archives of Oto-Rhino-Laryngology 269, pp. 1431-1435. Fulltext not available.

Kaftan, Holger, Göpferich, Achim , Kaftan, Silke and Hosemann, Werner (2012) Two different techniques to facilitate reconstruction of the long incus process with bone cement: a feasibility study in human cadaveric temporal bones. European Archives of Oto-Rhino-Laryngology 269 (5), pp. 1431-1435. Fulltext not available.

Jaumann, Mirko, Dettling, Juliane, Gubelt, Martin, Zimmermann, Ulrike, Gerling, Andrea, Paquet-Durand, François , Feil, Susanne , Wolpert, Stephan, Franz, Christoph, Varakina, Ksenya, Xiong, Hao, Brandt, Niels, Kuhn, Stephanie, Geisler, Hyun-Soon, Rohbock, Karin, Ruth, Peter, Schlossmann, Jens , Hütter, Joachim, Sandner, Peter, Feil, Robert , Engel, Jutta, Knipper, Marlies and Rüttiger, Lukas (2012) cGMP-Prkg1 signaling and Pde5 inhibition shelter cochlear hair cells and hearing function. Nature Medicine 18 (2), pp. 252-259. Fulltext not available.

Strasser, Andrea and Wittmann, Hans-Joachim (2012) hb2R-Gas-complex: Prediction versus crystal structure - How valuable are predictions based on molecular modelling studies? Journal of Molecular Modeling : J Mol Model 18, pp. 3439-3444. Fulltext not available.

Brunskole, Irena (2011) Molecular and cellular analysis of aminergic G protein-coupled receptors: histamine H2, H4 and β2-adrenergic receptors, a scientific paradigm. PhD, Universität Regensburg.

Geyer, Roland (2011) Hetarylalkyl(aryl)cyanoguanidines as histamine H4 receptor ligands: Synthesis, chiral separation, pharmacological characterization, structure-activity and -selectivity relationships. PhD, Universität Regensburg.

Lopuch, Miroslaw (2011) Investigations on neuropeptide Y and histamine receptors by fluorescence-based and radiochemical methods. PhD, Universität Regensburg.

Brunskole, Irena, Strasser, Andrea, Seifert, Roland and Buschauer, Armin (2011) Role of the second and third extracellular loops of the histamine H4 receptor in receptor activation. Naunyn-Schmiedeberg's Archives of Pharmacology 384 (3), pp. 301-317. Fulltext not available.

Braun, Stephan, Botzki, Alexander , Salmen, Sunnhild, Textor, Christian, Bernhardt, Günther, Dove, Stefan and Buschauer, Armin (2011) Design of benzimidazole- and benzoxazole-2-thione derivatives as inhibitors of bacterial hyaluronan lyase. European Journal of Medicinal Chemistry 46 (9), pp. 4419-4429. Fulltext not available.

Hübner, Melanie, Dixit, A., Mou, T.-C., Lushington, Gerald H., Pinto, Cibele S., Gille, A. , Geduhn, Jens, König, Burkhard , Sprang, S. R. and Seifert, Roland (2011) Structural Basis for the High-Affinity Inhibition of Mammalian Membranous Adenylyl Cyclase by 2`,3`-O-(N-Methylanthraniloyl)-Inosine 5`-Triphosphate. Molecular Pharmacology 80 (1), pp. 87-96. Fulltext not available.

Pluym, Nikola, Brennauer, Albert, Keller, Max, Ziemek, Ralf, Pop, Nathalie, Bernhardt, Günther and Buschauer, Armin (2011) Application of the guanidine – acylguanidine bioisosteric approach to argininamide-type NPY Y2 receptor antagonists. ChemMedChem 6 (9), pp. 1727-1738. Fulltext not available.

Klein, Matthias S. , Dorn, Christoph, Saugspier, Michael Sebastian, Hellerbrand, Claus, Oefner, Peter J. and Gronwald, Wolfram (2011) Discrimination of steatosis and NASH in mice using nuclear magnetic resonance spectroscopy. Metabolomics 7 (2), pp. 237-246. Fulltext not available.

Erdorf, Miriam and Seifert, Roland (2011) Pharmacological characterization of adenylyl cyclase isoforms in rabbit kidney membranes. Naunyn-Schmiedeberg's Archives of Pharmacology 383 (4), pp. 357-372. Fulltext not available.

Geyer, Roland and Buschauer, Armin (2011) Synthesis and histamine H3 and H4 receptor activity of conformationally restricted cyanoguanidines related to UR-PI376. Archiv der Pharmazie 344 (12), pp. 775-785. Fulltext not available.

Keller, Max, Bernhardt, Günther and Buschauer, Armin (2011) [3H]UR-MK136 - a highly potent and selective radioligand for neuropeptide Y Y1 receptors. ChemMedChem 6 (9), pp. 1566-1571. Fulltext not available.

Keller, Max, Erdmann, Daniela, Teng, Shangjun, Pop, Nathalie , Pluym, Nikola, Bernhardt, Günther and Buschauer, Armin (2011) Red-fluorescent argininamide-type NPY Y(1) receptor antagonists as pharmacological tools. Bioorganic & Medicinal Chemistry 19 (9), pp. 2859-2878. Fulltext not available.

Kellermann, K., Dertinger, N., Blobner, M., Kees, Frieder, Kochs, E. F. and Jungwirt, B. (2011) Perioperative moxifloxacin treatment in rats subjected to deep hypothermic circulatory arrest: reduction in cerebral inflammation but without improvement in cognitive performance. Journal of Thoracic and Cardiovascular Surgery 141 (3), pp. 796-802. Fulltext not available.

Schnell, David, Brunskole, Irena, Ladova, Katerina, Schneider, Erich H. , Igel, Patrick, Dove, Stefan, Buschauer, Armin and Seifert, Roland (2011) Expression and functional properties of canine, rat and murine histamine H4-receptors in Sf9 insect cells. Naunyn-Schmiedeberg's Archives of Pharmacology 383 (5), pp. 457-470. Fulltext not available.

Seifert, Roland, Schneider, Erich H. , Dove, Stefan, Brunskole, Irena, Neumann, Detlef , Strasser, Andrea and Buschauer, Armin (2011) Paradoxical stimulatory effects of the “standard” histamine H4-receptor antagonist JNJ7777120: The H4-receptor joins the club of 7TM receptors exhibiting functional selectivity. Molecular Pharmacology 79 (4), pp. 631-638. Fulltext not available.

Schinner, Elisabeth, Salb, Katharina and Schlossmann, Jens (2011) Signaling via IRAG is essential for NO/cGMP-dependent inhibition of platelet activitation. Platelets. Fulltext not available.

Silva, Maria Elena, Heim, Ralf, Strasser, Andrea, Elz, Sigurd and Dove, Stefan (2011) Theoretical studies on the interaction of partial agonists with the 5-HT(2A) receptor. Journal of computer-aided molecular design 25 (1), pp. 51-66. Fulltext not available.

Gäbele, Erwin, Dostert, Karin, Dorn, Christoph , Patsenker, Eleonora, Stickel, Felix and Hellerbrand, Claus (2011) A New Model of Interactive Effects of Alcohol and High-Fat Diet on Hepatic Fibrosis. Alcoholism: Clinical and Experimental Research 35 (7), pp. 1361-1367. Fulltext not available.

Wanninger, Josef, Neumeier, Markus, Bauer, Sabrina, Weiss, Thomas S. , Eisinger, Kristina, Walter, Roland, Dorn, Christoph , Hellerbrand, Claus, Schäffler, Andreas and Buechler, Christa (2011) Adiponectin induces the transforming growth factor decoy receptor BAMBI in human hepatocytes. FEBS Letters 585 (9), pp. 1338-1344. Fulltext not available.

Kelber, O, Okpanyi, SN, Freischmidt, A, Heinrich, EU, Müller, J, Heilmann, J, Ulrich Merzenich, G and Weiser, D (2011) Antidepressant mechanisms of action of willow bark extract STW 33-I. Planta Medica 77 (12). Fulltext not available.

Kees, Frieder, Jehkul, Andreas, Bucher, Michael, Mair, Georg, Kiermaier, Josef and Grobecker, Horst (2011) Bioavailability of Opipramol from a Film-coated Tablet, a Sugar-coated Tablet and an Aqueous Solution in Healthy Volunteers. Arzneimittelforschung 53 (02), pp. 87-92. Fulltext not available.

Knuth, Susanne, Schübel, Helmut, Hellemann, Martin and Jürgenliemk, Guido (2011) Catechol, a Bioactive Degradation Product of Salicortin, Reduces TNF-αInduced ICAM-1 Expression in Human Endothelial Cells. Planta Medica 77 (10), pp. 1024-1026. Fulltext not available.

Gonenc, T., Argyropoulou, C., Erdogan, T., Gousiadou, C., Juergenliemk, G., Kıvçak, B. and Skaltsa, H. (2011) Chemical constituents from Anthemis wiedemanniana Fisch. & Mey. Biochemical Systematics and Ecology 39 (1), pp. 51-55. Fulltext not available.

Ulrich Merzenich, G, Koptina, A, Kelber, O, Freischmidt, A, Heilmann, J, Müller, J, Zeitler, H, Panek, D and Winterhoff, H (2011) Comparative analysis of gene expression profiles from rats treated with a standardized willow bark preparation, its salicin rich ethanol fraction and imipramine for toxicological endpoints. Planta Medica 77 (12). Fulltext not available.

Scheruebl, R, Orland, A, Demirci, B, Knoess, W, Başer, KHC, Franz, G and Heilmann, J (2011) Comprehensive Analysis of Artemisiae scopariae herba from different growing areas. Planta Medica 77 (12). Fulltext not available.

Osman, Shaaban, Brandl, Ferdinand, Zayed, Gamal , Teßmar, Jörg and Göpferich, Achim (2011) Cyclodextrin based hydrogels: Inclusion complex formation and micellization of adamantane and cholesterol grafted polymers. Polymer 52 (21), pp. 4806-4812. Fulltext not available.

Hübner, Melanie, Dizayee, Sara, Matthes, Jan, Seifert, Roland and Herzig, Stefan (2011) Effect of MANT-nucleotides on L-type calcium currents in murine cardiomyocytes. Naunyn-Schmiedeberg's Archives of Pharmacology 383 (6), pp. 573-583. Fulltext not available.

Pertz, Heinz, Lehmann, Jochen, Roth-Ehrang, René and Elz, Sigurd (2011) Effects of Ginger Constituents on the Gastrointestinal Tract: Role of Cholinergic M3and Serotonergic 5-HT3and 5-HT4Receptors. Planta Medica 77 (10), pp. 973-978. Fulltext not available.

Kokanova Nedialkova, Z, Bücherl, D, Nikolov, S, Heilmann, J and Nedialkov, P (2011) Flavonol glycosides and a saponin from Chenopodium foliosum Asch. Planta Medica 77 (12). Fulltext not available.

Kokanova-Nedialkova, Zlatina , Bücherl, Daniel, Nikolov, Stefan, Heilmann, Jörg and Nedialkov, Paraskev T. (2011) Flavonol glycosides from Chenopodium foliosum Asch. Phytochemistry Letters 4 (3), pp. 367-371. Fulltext not available.

Franz, G (2011) Globalisation of TCM Herbal Drugs: Quality Monographs for the European Pharmacopoeia. Planta Medica 77 (12). Fulltext not available.

Rossbach, K., Nassenstein, C., Gschwandtner, M. , Schnell, D., Sander, K., Seifert, R., Stark, H. , Kietzmann, M. and Bäumer, W. (2011) Histamine H1, H3 and H4 receptors are involved in pruritus. Neuroscience 190, pp. 89-102. Fulltext not available.

Schaedlich, A., Rose, C., Kuntsche, J., Caysa, H., Mueller, T., Goepferich, Achim and Maeder, K. (2011) How Stealthy are PEG-PLA Nanoparticles? An NIR In Vivo Study Combined with Detailed Size Measurements. Pharmaceutical Research 28 (8), pp. 1995-2007. Fulltext not available.

Decker, M. (2011) Hybrid Molecules Incorporating Natural Products: Applications in Cancer Therapy, Neurodegenerative Disorders and Beyond. Current Medicinal Chemistry 18 (10), pp. 1464-1475. Fulltext not available.

Schlossmann, Jens and Desch, M. (2011) IRAG and Novel PKG Targeting in the cardiovascular system. American Journal of Physiology- Heart und Circulatory Physiology 301, H672-682. Fulltext not available.

Erdorf, Miriam, Mou, Tung-Chung and Seifert, Roland (2011) Impact of divalent metal ions on regulation of adenylyl cyclase isoforms by forskolin analogs. Biochemical Pharmacology 82 (11), pp. 1673-1681. Fulltext not available.

Sutor, Sarah, Heilmann, Jörg and Seifert, Roland (2011) Impact of fusion to Gαi2 and co-expression with RGS proteins on pharmacological properties of human cannabinoid receptors CB1R and CB2R. Journal of Pharmacy and Pharmacology 63 (8), pp. 1043-1055. Fulltext not available.

Erdorf, Miriam, von der Ohe, Juliane and Seifert, Roland (2011) Impaired P2X and P2Y receptor-mediated signaling in HPRT-deficient B103 neuroblastoma cells. Neuroscience Letters 504 (3), pp. 311-315. Fulltext not available.

Wittmann, Hans-Joachim, Seifert, Roland and Strasser, Andrea (2011) Influence of the N-terminus and the E2-loop onto the binding kinetics of the antagonist mepyramine and the partial agonist phenoprodifen to H1R. Biochemical Pharmacology 12, pp. 1910-1918. Fulltext not available.

Ertl, C., Lukowski, R., Sigl, K., Schlossmann, Jens , Hofmann, F. and Wegener, Jörg W. (2011) Kinetics of relaxation by cGMP/cGKI signaling in fundus smooth muscle. Eur J Pharmacol 670 (1), pp. 266-271. Fulltext not available.

Bradacs, Gesine, Heilmann, Jörg and Weckerle, Caroline S. (2011) Medicinal plant use in Vanuatu: A comparative ethnobotanical study of three islands. Journal of Ethnopharmacology 137 (1), pp. 434-448. Fulltext not available.

Wagner, Eva, Wittmann, Hans-Joachim, Elz, Sigurd and Strasser, Andrea (2011) Mepyramine-JNJ7777120-hybrid compounds show high affinity to hH1R, but low affinity to hH4R. Bioorganic & Medicinal Chemistry Letters 21, pp. 6274-9280. Fulltext not available.

Oberprieler, Christoph, Hartl, Sabine, Schauer, Kerstin, Meister, Jörg and Heilmann, Jörg (2011) Morphological, phytochemical and genetic variation in mixed stands and a hybrid swarm of Senecio germanicus and S. ovatus (Compositae, Senecioneae). Plant Systematics and Evolution 293 (1-4), pp. 177-191. Fulltext not available.

Macabeo, Allan Patrick G., Vidar, Warren S., Chen, Xinyu, Decker, Michael, Heilmann, Jörg, Wan, Baojie, Franzblau, Scott G. , Galvez, Elano V., Aguinaldo, Ma. Alicia M. and Cordell, Geoffrey A. (2011) Mycobacterium tuberculosis and cholinesterase inhibitors from Voacanga globosa. European Journal of Medicinal Chemistry 46 (7), pp. 3118-3123. Fulltext not available.

Wittmann, Hans-Joachim, Elz, Sigurd, Seifert, Roland and Strasser, Andrea (2011) Na-methylated phenylhistamines exhibit affinity to the hH4R - a pharmacological and molecular modelling study. Naunyn Schmiedeberg's Arch Pharmacol 384, pp. 287-299. Fulltext not available.

Ferstl, Matthias, Strasser, Andrea, Wittmann, Hans-Joachim, Drechsler, Markus , Rischer, M., Engl, J. and Goepferich, Achim (2011) Nanofibres Resulating from Cooperative Electrostatic and Hydrophobic Interactions between Peptides and Polyelectrolytes of Opposite Charge. Langmuir 27, pp. 14450-14459. Fulltext not available.

Henkel, Janin, Gärtner, Daniela, Dorn, Christoph , Hellerbrand, Claus, Schanze, Nancy, Elz, Sheila R. and Püschel, Gerhard P. (2011) Oncostatin M produced in Kupffer cells in response to PGE2: possible contributor to hepatic insulin resistance and steatosis. Laboratory Investigation 91 (7), pp. 1107-1117. Fulltext not available.

Kees, Martin G., Weber, Susanne, Kees, Frieder K. and Horbach, Thomas (2011) Pharmacokinetics of moxifloxacin in plasma and tissue of morbidly obese patients. The Journal of antimicrobial chemotherapy 66 (10), pp. 2330-2335. Fulltext not available.

Erdorf, Miriam and Seifert, Roland (2011) Pharmacological characterization of adenylyl cyclase isoforms in rabbit kidney membranes. Naunyn-Schmiedeberg's Archives of Pharmacology 383 (4), pp. 357-372. Fulltext not available.

Posavec, Damir, Dorsch, Andre, Bogner, Udo, Bernhardt, Guenther and Nagl, Stefan (2011) Polyvinyl butyral nanobeads: preparation, characterization, biocompatibility and cancer cell uptake. Microchimica acta 173 (3-4), pp. 391-399. Fulltext not available.

Patsenker, Eleonora, Schneider, Vreni, Ledermann, Monika, Saegesser, Hans, Dorn, Christoph , Hellerbrand, Claus and Stickel, Felix (2011) Potent antifibrotic activity of mTOR inhibitors sirolimus and everolimus but not of cyclosporine A and tacrolimus in experimental liver fibrosis. Journal of Hepatology 55 (2), pp. 388-398. Fulltext not available.

Chen, Xinyu, Tikhonova, Irina G. and Decker, Michael (2011) Probing the mid-gorge of cholinesterases with spacer-modified bivalent quinazolinimines leads to highly potent and selective butyrylcholinesterase inhibitors. Bioorganic & Medicinal Chemistry 19 (3), pp. 1222-1235. Fulltext not available.

Schinner, Elisabeth, Salb, Katharina and Schlossmann, Jens (2011) Signaling via IRAG is essential for NO/cGMP-dependent inhibition of platelet activation. Platelets 22 (3), pp. 217-227. Fulltext not available.

Ochoa Puentes, Cristian, Höcherl, Peter, Kühnle, Matthias, Bauer, Stefanie, Kürger, Kira, Bernhardt, Günther, Buschauer, Armin and König, Burkhard (2011) Solid phase synthesis of tariquidar-related modulators of ABC transporters preferring breast cancer resistance protein (ABCG2). Bioorganic & Medicinal Chemistry Letters 21 (12), pp. 3654-3657. Fulltext not available.

Bauer, Sabrina, Wanninger, Josef, Schmidhofer, Sandra, Weigert, Johanna, Neumeier, Markus, Dorn, Christoph , Hellerbrand, Claus, Zimara, Nicole, Schäffler, Andreas, Aslanidis, Charalampos and Buechler, Christa (2011) Sterol Regulatory Element-Binding Protein 2 (SREBP2) Activation after Excess Triglyceride Storage Induces Chemerin in Hypertrophic Adipocytes. Endocrinology 152 (1), pp. 26-35. Fulltext not available.

Weiss, Stefan, Bernhardt, Günther, Buschauer, Armin and König, Burkhard (2011) Synthesis and characterization of DMAP-Modified NPY Y1 receptor antagonists as acyl-transfer catalysts. Collection of Czechoslovak chemical communications 76 (6), 763 -780. Fulltext not available.

Mannschreck, Albrecht and von Angerer, Erwin (2011) The Scent of Roses and Beyond: Molecular Structures, Analysis, and Practical Applications of Odorants. Journal of Chemical Education 88 (11), pp. 1501-1506. Fulltext not available.

Werder, A., Mayr, M., Schneider, G., Oesterle, D., Fritsch, R. M., Seidler, B., Schlossmann, Jens , Hofmann, F., Schemann, M. , Allescher, H. D., Schmid, R. M. and Saur, D. (2011) Truncated IRAG variants modulate cGMP-mediated inhibition of human colonic smooth muscle cell contraction. American Journal of Physiology - Cell Physiology : Am J Physiol Cell Physiol 301 (6), C1445-1457. Fulltext not available.

Schaedlich, A., Caysa, H., Mueller, T., Tenambergen, F., Rose, Cornelia, Goepferich, Achim , Kuntsche, J. and Maeder, K. (2011) Tumor Accumulation of NIR Fluorescent PEG PLA Nanoparticles: Impact of Particle Size and Human Xenograft Tumor Model. ACS Nano 5, pp. 8710-8720. Fulltext not available.

Wolff, Horst, Motyl, Magdalena, Hellerbrand, Claus, Heilmann, Jörg and Kraus, Birgit (2011) Xanthohumol Uptake and Intracellular Kinetics in Hepatocytes, Hepatic Stellate Cells, and Intestinal Cells. Journal of Agricultural and Food Chemistry 59 (24), pp. 12893-12901. Fulltext not available.

Igel, Patrick, Dove, Stefan and Buschauer, Armin (2010) Histamine H4 receptor agonists. Bioorganic & Medicinal Chemistry Letters 20 (24), pp. 7191-7199. Fulltext not available.

Dayoub, Rania , Wagner, Hannah, Bataille, Frauke, Stöltzing, Oliver, Spruss, Thilo, Buechler, Christa, Schlitt, Hans-Jürgen and Weiss, Thomas S. (2010) Liver Regeneration Associated Protein (ALR) Exhibits Antimetastatic Potential in Hepatocellular Carcinoma. Molecular Medicine 17, pp. 221-228.

Modrow, Susanne, Wenzel, J. J. , Schimanski, S., Schwarzbeck, J., Rothe, U., Oldenburg, J., Jilg, W. and Eis-Hübinger, A. M. (2010) Prevalence of nucleic acid sequences specific for human parvoviruses, hepatitis A and hepatitis E viruses in coagulation factor concentrates. Vox sanguinis. Fulltext restricted.

Kees, M. G., Hilpert, J. W., Gnewuch, C., Kees, F. and Voegeler, S. (2010) Clearance of vancomycin during continuous infusion in intensive care unit patients: correlation with measured and estimated creatinine clearance and serum cystatin C. International Journal of Antimicrobial Agents 36 (6), pp. 545-548. Fulltext not available.

Schnell, David, Strasser, Andrea and Seifert, Roland (2010) Comparison of the pharmacological properties of human and rat histamine H(3)-receptors. Biochemical Pharmacology 80 (9), pp. 1437-1449. Fulltext not available.

Mathar, I., Vennekens, R., Meissner, M., Kees, Frieder K., Van der Mieren, G. and Camacho Londono, J. (2010) Increased catecholamine secretion contributes to hypertension in TRPM4-deficient mice. The Journal of Clinical Investigation 120 (9), pp. 3267-3279. Fulltext not available.

Desch, Matthias, Schinner, Elisabeth, Kees, Frieder K., Hofmann, F., Seifert, Roland and Schlossmann, Jens (2010) Cyclic cytidine 3´,5´-monophosphate (cCMP) signals via cGMP kinase I. FEBS Letters 584 (18), pp. 3979-3984. Fulltext not available.

Kirovski, Georgi, Gäbele, Erwin, Dorn, Christoph , Moleda, Lukas, Niessen, Christoph, Weiss, Thomas S. , Wobser, Hella, Schacherer, Doris, Buechler, Christa , Wasmuth, Hermann E. and Hellerbrand, Claus (2010) Hepatic steatosis causes induction of the chemokine RANTES in the absence of significant hepatic inflammation. International Journal of Clinical and Experimental Pathology 3 (7), pp. 675-680.

Schneider, E. H., Strasser, Andrea, Thurmond, R. L. and Seifert, Roland (2010) Structural requirements for inverse agonism and neutral antagonism of indole-, benzimidazole-, and thienopyrrole-derived histamine H4 receptor ligands. Journal of Pharmacology and Experimental Therapeutics 334 (2), pp. 513-521. Fulltext not available.

Desch, Matthias, Sigl, K., Hieke, Bernhard, Salb, Katharina, Kees, F., Bernhard, D., make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference , make_name_string expected hash reference , make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference and make_name_string expected hash reference (2010) IRAG determines nitric oxide- and atrial natriuretic peptide-mediated smooth muscle relaxation. Cardiovascular Research 86 (3), pp. 496-505. Fulltext not available.

Ghorai, Prasanta, Kraus, Anja, Birnkammer, Tobias, Geyer, Roland, Bernhardt, Günther, Dove, Stefan, Seifert, Roland, Elz, Sigurd and Buschauer, Armin (2010) Chiral N(G)-acylated hetarylpropylguanidine-type histamine H2 receptor agonists do not show significant stereoselectivity. Bioorganic & Medicinal Chemistry Letters 20 (10), pp. 3173-3176. Fulltext not available.

Dorn, Christoph , Riener, Marc-Oliver, Kirovski, Georgi, Saugspier, Michael, Steib, Kathrin, Weiss, Thomas S. , Gäbele, Erwin, Kristiansen, Glen, Hartmann, Arndt and Hellerbrand, Claus (2010) Expression of fatty acid synthase in nonalcoholic fatty liver disease. International Journal of Clinical and Experimental Pathology 3 (5), pp. 505-514.

Schnell, David and Seifert, Roland (2010) Modulation of Histamine H(3) receptor function by monovalent ions. Neuroscience Letters 472 (2), pp. 114-118. Fulltext not available.

Schnell, David, Burleigh, Katrina, Seifert, Roland and Trick, Jonathan (2010) No evidence for functional selectivity of proxyfan at the human histamine H3 receptor coupled to defined Gi/Go protein heterotrimers. Journal of Pharmacology and Experimental Therapeutics . JPET 332 (3), pp. 996-1005. Fulltext not available.

Strasser, Andrea and Wittmann, Hans-Joachim (2010) 3D-QSAR CoMFA study to predict orientation of suprahistaprodifens and phenoprodifens in the binding-pocket of four histamine H1-receptor species. Molecular Informatics 29, pp. 333-341. Fulltext not available.

Barbic, M, Willer, E, Fürst, R and Jürgenliemk, G (2010) Aesculin from Butcher's broom reduces the permeability of endothelial cells in vitro. Planta Medica 76 (12). Fulltext not available.

Schoenhammer, K., Boisclair, J., Schuetz, H., Petersen, H. and Göpferich, Achim (2010) Biocompatibility of an injectable in situ forming depot for peptide delivery. European Journal of Pharmaceutical Sciences 99 (10), pp. 4390-4399. Fulltext not available.

Brandl, Ferdinand, Hammer, Nadine, Blunk, Torsten, Teßmar, Jörg and Göpferich, Achim (2010) Biodegradable hydrogels for time-controlled release of tethered peptides or proteins. Biomacromolecules 11 (2), pp. 496-504. Fulltext not available.

Feizlmayr, E, Sutor, S, Stinglmayr, I, Kunert, O, Heilmann, J and Bauer, R (2010) Cannabinoid receptor activity of polyacetylenes and polyenes from Echinacea pallida. Planta Medica 76 (12). Fulltext not available.

Bauer-Kreisel, Petra, Göpferich, Achim and Blunk, Torsten (2010) Cell-delivery therapeutics for adipose tissue regeneration. Advanced Drug Delivery Reviews 62 (7-8), pp. 798-813. Fulltext not available.

Uecker, Andrea, Sicker, Marit, Beckers, Thomas, Mahboobi, Siavosh, Hägerstrand, Daniel , Östman, Arne and Böhmer, Frank-D. (2010) Chimeric tyrosine kinase-HDAC inhibitors as antiproliferative agents. Anti-Cancer Drugs 21 (8), pp. 759-765. Fulltext not available.

Göttle, Martin, Dove, Stefan, Kees, Frieder K., Schlossmann, Jens , Geduhn, Jens, König, Burkhard , Shen, Y., Tang, W. J. , Kaever, V. and Seifert, Roland (2010) Citidylyl and uridylyl cyclase activity of bacillus anthracis edema factor and Bordetella pertussis CyaA. Biochemistry 49, pp. 5494-5503. Fulltext not available.

Kees, Martin G., Hilpert, Justus W., Gnewuch, Carsten, Kees, Frieder and Voegeler, Stephan (2010) Clearance of vancomycin during continuous infusion in Intensive Care Unit patients: correlation with measured and estimated creatinine clearance and serum cystatin C. International Journal of Antimicrobial Agents 36 (6), pp. 545-548. Fulltext not available.

Schnell, David, Strasser, Andrea and Seifert, Roland (2010) Comparison of the pharmacological properties of human and rat histamine H3-receptors. Biochemical Pharmacology 80 (9), pp. 1437-1449. Fulltext not available.

Kleinmaier, Roland, Igel, Patrick, Keller, Max, Buschauer, Armin and Gschwind, Ruth M. (2010) Conformations, Conformational Preferences, and Conformational Exchange of N'-Substituted N-Acylguanidines: Intermolecular Interactions Hold the Key. J. Am. Chem. Soc. 132 (32), pp. 11223-11233. Fulltext not available.

Desch, Matthias, Schinner, Elisabeth, Kees, Frieder, Hofmann, Franz, Seifert, Roland and Schlossmann, Jens (2010) Cyclic cytidine 3′,5′‐monophosphate (cCMP) signals via cGMP kinase I. FEBS Letters 584 (18), pp. 3979-3984. Fulltext not available.

Barbič, Matej, Macabeo, Allan Patrick G., Kreft, Samo and Heilmann, Jörg (2010) Cycloastragenol glycosides from Astragalus illyricus. Biochemical Systematics and Ecology 38 (3), pp. 460-462. Fulltext not available.

Shwe, Htay Htay, Aye, Mye, Sein, Myint Myint, Htay, Khin Than, Kreitmeier, Peter, Gertsch, Jürg, Reiser, Oliver and Heilmann, Jörg (2010) Cytotoxic Steroidal Saponins from the Rhizomes of Tacca integrifolia. Chemistry & Biodiversity 7 (3), pp. 610-622. Fulltext not available.

Schmidt, Florian, Schmidt, J., Riechers, A., Haase, S., Bosserhoff, Anja-Katrin, Heilmann, J. and König, Burkhard (2010) DNA Staining in Agarose Gels with Zn2+ -Cyclen-Pyrene. Nucleosides, Nucleotides & Nucleic Acids (29), pp. 748-759. Fulltext not available.

Strasser, Andrea and Wittmann, Hans-Joachim (2010) Distinct interactions between the human adrenergic b2 receptor and Gas - an in silico study. J Mol Model 16, pp. 1307-1318. Fulltext not available.

Brandl, Ferdinand, Seitz, Anna Katharina, Teßmar, Jörg , Blunk, Torsten and Göpferich, Achim (2010) Enzymatically degradable poly(ethylene glycol) based hydrogels for adipose tissue engineering. Biomaterials 31 (14), pp. 3957-3966. Fulltext not available.

Geiger, Sarah, Nickl, Kathrin, Schneider, Erich H. , Seifert, Roland and Heilmann, Jörg (2010) Establishment of recombinant cannabinoid receptor assays and characterization of several natural and synthetic ligands. Naunyn-Schmiedeberg's Archives of Pharmacology 382 (2), pp. 177-191. Fulltext not available.

Sander, Kerstin, Kottke, Tim, Hoffend, Claas, Walter, Miriam, Weizel, Lilia, Camelin, Jean-Claude, Ligneau, Xavier, Schneider, Erich H. , Seifert, Roland, Schwartz, Jean-Charles and Stark, Holger (2010) First Metal-Containing Histamine H3 Receptor Ligands. Organic Letters 12 (11), pp. 2578-2581. Fulltext not available.

Brandl, Ferdinand, Kastner, Fritz, Gschwind, R. M. , Blunk, Torsten, Teßmar, Jörg and Göpferich, Achim (2010) Hydrogel-based drug delivery systems: Comparison of drug diffusivity and release kinetics. Journal of Controlled Release 142 (2), pp. 221-228. Fulltext not available.

Kraus, Birgit, Wolff, Horst, Elstner, Erich F. and Heilmann, Jörg (2010) Hyperforin is a modulator of inducible nitric oxide synthase and phagocytosis in microglia and macrophages. Naunyn-Schmiedeberg's Archives of Pharmacology 381 (6), pp. 541-553. Fulltext not available.

Desch, M., Sigl, K., Hieke, B., Salb, Katharina, Kees, Frieder, Bernhard, D., Jochim, A., Spiessberger, B., Höcherl, K., Feil, R. , Lukowski, R. , Wegener, Jörg W., Hofmann, F., Schlossmann, Jens and make_name_string expected hash reference (2010) IRAG determines NO- and ANP-mediated smooth muscle relaxation. Cardiovascular Research 86 (3), pp. 496-505. Fulltext not available.

Berndl, Sina, Breunig, Miriam , Göpferich, Achim and Wagenknecht, Hans-Achim (2010) Imaging of RNA delivery to cells by thiazole orange as a fluorescent RNA base substitution. Organic & Biomolecular Chemistry 8 (5), pp. 997-999. Fulltext not available.

Schneider, Erich , Schnell, David, Strasser, Andrea, Dove, Stefan and Seifert, Roland (2010) Impact of the DRY motif and the missing "ionic lock" on constitutive activity and G-protein coupling of the human histamine H4 receptor. J Pharmacol Exp Ther : The journal of pharmacology and experimental therapeutics 333 (2), pp. 382-392. Fulltext not available.

Strasser, Andrea and Wittmann, Hans-Joachim (2010) In silico analysis of the histaprodifen induced pathway of the guinea-pig histamine H1 receptor. Journal of computer- aided molecular design : J Comput Aided Mol Des 24, pp. 759-769. Fulltext not available.

Bradacs, Gesine, Maes, Louis and Heilmann, Jörg (2010) In vitro cytotoxic, antiprotozoal and antimicrobial activities of medicinal plants from Vanuatu. Phytotherapy Research 24 (6), pp. 800-809. Fulltext not available.

Mathar, Ilka, Vennekens, Rudi , Meissner, Marcel, Kees, Frieder, Van der Mieren, Gerry, Camacho Londoño, Juan E., Uhl, Sebastian, Voets, Thomas , Hummel, Björn, van den Bergh, An, Herijgers, Paul , Nilius, Bernd, Flockerzi, Veit, Schweda, Frank and Freichel, Marc (2010) Increased catecholamine secretion contributes to hypertension in TRPM4-deficient mice. Journal of Clinical Investigation 120 (9), pp. 3267-3279. Fulltext not available.

Kraus, B, Wolff, H, Elstner, E and Heilmann, J (2010) Influence of Saint John's wort (Hypericum perforatum) constituent hyperforin on phagocytosis and inducible nitric oxide synthase (iNOS) in microglia. Planta Medica 76 (12). Fulltext not available.

Höcherl, Klaus, Schmidt, Christoph, Kurt, Birgül and Bucher, Michael (2010) Inhibition of NF-κB ameliorates sepsis-induced downregulation of aquaporin-2/V2receptor expression and acute renal failure in vivo. American Journal of Physiology-Renal Physiology 298 (1), F196-F204. Fulltext not available.

Dietl, Katrin, Renner, Kathrin, Dettmer, Katja , Timischl, Birgit, Eberhart, Karin, Dorn, Christoph, Hellerbrand, Claus, Kastenberger, Michael, Kunz-Schughart, Leoni A., Oefner, Peter J. , Andreesen, Reinhard, Gottfried, Eva and Kreutz, Marina (2010) Lactic acid and acidification inhibit TNF secretion and glycolysis of human monocytes. Journal of immunology 184 (3), pp. 1200-1209. Fulltext not available.

O'Connor, Richard M. , Finger, Beate C., Flor, Peter J. and Cryan, John F. (2010) Metabotropic glutamate receptor 7: At the interface of cognition and emotion. European Journal of Pharmacology 639 (1-3), pp. 123-131. Fulltext not available.

Bauer, Rudolf and Franz, Gerhard (2010) Modern European Monographs for Quality Control of Chinese Herbs. Planta Medica 76 (17), pp. 2004-2011. Fulltext not available.

Schnell, David and Seifert, Roland (2010) Modulation of histamine H3 receptor function by monovalent ions. Neuroscience Letters 472 (2), pp. 114-118. Fulltext not available.

Oberprieler, Christoph, Barth, A., Schwarz, S. and Heilmann, J. (2010) Morphological and phytochemical variation, genetic structure and phenology in an introgressive hybrid swarm of Senecio hercynicus and S. ovatus (Compositae, Senecioneae). Plant Systematics and Evolution 286 (3-4), pp. 153-166. Fulltext not available.

Weiss, Stefan, Keller, Max, Bernhardt, G., Buschauer, Armin and König, Burkhard (2010) N(G)-Acyl-argininamides as NPY Y (1) receptor antagonists: Influence of structurally diverse acyl substituents on stability and affinity. Bioorganic & Medicinal Chemistry (18), pp. 6292-6304. Fulltext not available.

Mahboobi, Siavosh, Sellmer, Andreas, Winkler, Matthias, Eichhorn, Emerich, Pongratz, Herwig, Ciossek, Thomas, Baer, Thomas, Maier, Thomas and Beckers, Thomas (2010) Novel Chimeric Histone Deacetylase Inhibitors: A Series of Lapatinib Hybrides as Potent Inhibitors of Epidermal Growth Factor Receptor (EGFR), Human Epidermal Growth Factor Receptor 2 (HER2), and Histone Deacetylase Activity. Journal of Medicinal Chemistry 53 (24), pp. 8546-8555. Fulltext not available.

Freischmidt, A, Jürgenliemk, G, Kraus, B, Okpanyi, S, Müller, J, Kelber, O, Weiser, D and Heilmann, J (2010) Phenolic compounds in the ethyl acetate fraction of a standardized willow bark extract. Planta Medica 76 (12). Fulltext not available.

Schempp, Harald, Vogel, Susanne, Hückelhoven, Ralph and Heilmann, Jörg (2010) Re-evaluation of superoxide scavenging capacity of xanthohumol. Free Radical Research 44 (12), pp. 1435-1444. Fulltext not available.

Amann, Thomas, Bataille, Frauke, Spruss, Thilo, Dettmer, Katja , Wild, Peter J., Liedtke, Christian , Mühlbauer, Marcus, Kiefer, Paul, Oefner, Peter J. , Trautwein, Christian, Bosserhoff, Anja-Katrin and Hellerbrand, Claus (2010) Reduced expression of fibroblast growth factor receptor 2IIIb in hepatocellular carcinoma induces a more aggressive growth. The American journal of pathology 176 (3), pp. 1433-1442. Fulltext not available.

Henke, Matthias, Brandl, Ferdinand, Göpferich, Achim and Teßmar, Jörg (2010) Size-dependent release of fluorescent macromolecules and nanoparticles from radically cross-linked hydrogels. European Journal of Pharmaceutics and Biopharmaceutics 74 (2), pp. 184-192. Fulltext not available.

Jandt, Enrico, Mutschke, Oliver, Mahboobi, Siavosh, Uecker, Andrea, Platz, Ronny, Berndt, Alexander, Böhmer, Frank-D., Figulla, Hans R. and Werner, Gerald S. (2010) Stent-based release of a selective PDGF-receptor blocker from the bis-indolylmethanon class inhibits restenosis in the rabbit animal model. Vascular Pharmacology 52 (1-2), pp. 55-62. Fulltext not available.

Schneider, Erich H. , Strasser, Andrea, Thurmond, Robin L. and Seifert, Roland (2010) Structural Requirements for Inverse Agonism and Neutral Antagonism of Indole-, Benzimidazole-, and Thienopyrrole-Derived Histamine H4 Receptor Ligands. Journal of Pharmacology and Experimental Therapeutics 334 (2), pp. 513-521. Fulltext not available.

Holzhauser, C., Berndl, Sina, Menacher, Florian, Breunig, Miriam , Göpferich, Achim and Wagenknecht, Hans-Achim (2010) Synthesis and Optical Properties of Cyanine Dyes as Fluorescent DNA Base Substitutions for Live Cell Imaging. European Journal of Organic Chemistry (7), pp. 1239-1248. Fulltext not available.

Emmrich, Thomas, El-Tayeb, Ali, Taha, Hesham, Seifert, Roland, Müller, Christa E. and Link, Andreas (2010) Synthesis of a hydrolytically stable, fluorescent-labeled ATP analog as a tool for probing adenylyl cyclases. Bioorganic & Medicinal Chemistry Letters 20 (1), pp. 232-235. Fulltext not available.

Vogel, Susanne, Barbic, Matej, Jürgenliemk, Guido and Heilmann, Jörg (2010) Synthesis, cytotoxicity, anti-oxidative and anti-inflammatory activity of chalcones and influence of A-ring modifications on the pharmacological effect. European Journal of Medicinal Chemistry 45 (6), pp. 2206-2213. Fulltext not available.

Korte, G., Dreiseitel, A., Schreier, P., Oehme, A., Locher, S., Geiger, S., Heilmann, J. and Sand, P.G. (2010) Tea catechins’ affinity for human cannabinoid receptors. Phytomedicine 17 (1), pp. 19-22. Fulltext not available.

Fürst, R, Bubik, M, Bihari, P, Jürgenliemk, G, Ammer, H, Krombach, F, Zahler, S and Vollmar, A (2010) The hawthorn special extract WS® 1442 protects against endothelial barrier dysfunction – elucidation of the underlying molecular mechanisms. Planta Medica 76 (12). Fulltext not available.

Zaky, A., Elbakry, Asmaa, Ehmer, Axel, Breunig, Miriam and Göpferich, Achim (2010) The mechanism of protein release from triglyceride microspheres. Journal of Controlled Release 147 (2), pp. 202-210. Fulltext not available.

Wenzel-Seifert, K., Wittmann, M. and Haen, E. (2010) Torsade de Pointes Episodes under Treatment with Selective Serotonin Reuptake Inhibitors. Pharmacopsychiatry 43 (07), pp. 279-281. Fulltext not available.

Schmidt, S, Skaltsa, H, Jürgenliemk, G and Heilmann, J (2010) Two novel phloroglucinols from Hypericum empetrifolium with antiproliferative activity on endothelial cells. Planta Medica 76 (12). Fulltext not available.

Seemann, Andreas, Wallner, Teresa, Poschlod, Peter and Heilmann, Jörg (2010) Variation of Sesquiterpene Lactone Contents in DifferentArnica montanaPopulations: Influence of Ecological Parameters. Planta Medica 76 (08), pp. 837-842. Fulltext not available.

Dorn, Christoph , Bataille, Frauke, Gaebele, Erwin, Heilmann, Jörg and Hellerbrand, Claus (2010) Xanthohumol feeding does not impair organ function and homoeostasis in mice. Food and Chemical Toxicology 48 (7), pp. 1890-1897. Fulltext not available.

Dorn, Christoph, Bataille, Frauke, Gaebele, Erwin, Heilmann, Jörg and Hellerbrand, Claus (2010) Xanthohumol feeding does not impair organ function and homoeostasis in mice. Food and Chemical Toxicology 48 (7), pp. 1890-1897. Fulltext not available.

Dorn, Christoph, Kraus, Birgit, Motyl, Magdalena, Weiss, Thomas S. , Gehrig, Manfred, Schoelmerich, Juergen, Heilmann, Jörg and Hellerbrand, Claus (2010) Xanthohumol, a chalcon derived from hops, inhibits hepatic inflammation and fibrosis. Molecular nutrition & food research 54 (Suppl.), S205-S213. Fulltext not available.

Dorn, Christoph, Weiss, Thomas S. , Heilmann, Jörg and Hellerbrand, Claus (2010) Xanthohumol, a prenylated chalcone derived from hops, inhibits proliferation, migration and interleukin-8 expression of hepatocellular carcinoma cells. International journal of oncology 36 (2), pp. 435-441. Fulltext not available.

Göpferich, Achim and Rothschenk, Stefan (2009) Cross-linked polymer matrix, in particular for administering protein drugs into the eye. DE102008016998. Fulltext not available.

Igel, Patrick, Geyer, Roland, Straßer, Andrea, Dove, Stefan, Seifert, Roland and Buschauer, Armin (2009) Synthesis and structure-activity relationships of cyanoguanidine-type and structurally related histamine H(4) receptor agonists. Journal of Medicinal Chemistry 52 (20), pp. 6297-6313. Fulltext not available.

Schoenhammer, K., Petersen, H., Guethlein, F. and Göpferich, Achim (2009) Poly(ethylene-glycol) 500 Dimethylether as Novel Solvent for Injectable In Situ Forming Depots. Pharmaceutical Research 26 (12), pp. 2568-2577. Fulltext not available.

Igel, Patrick, Schneider, Erich , Schnell, David, Elz, Sigurd, Seifert, Roland and Buschauer, Armin (2009) N(G)-Acylated imidazolylpropylguanidines as potent histamine H4 receptor agonists: selectivity by variation of the N(G)-substituent. Journal of Medicinal Chemistry 52 (8), pp. 2623-2627. Fulltext not available.

Kraus, Anja, Ghorai, Prasanta, Birnkammer, Tobias, Schnell, David, Elz, Sigurd, Seifert, Roland, Dove, Stefan, Bernhardt, Günther and Buschauer, Armin (2009) N(G)-Acylated aminothiazolylpropylguanidines as potent and selective histamine H2 receptor agonists. ChemMedChem 4 (2), pp. 232-240. Fulltext not available.

Igel, Patrick, Schnell, David, Bernhardt, Günther, Seifert, Roland and Buschauer, Armin (2009) Tritium-labeled N1-[3-(1H-imidazol-4-yl)propyl]-N2-propionylguanidine ([3H]UR-PI294), a high affinity histamine H3 and H4 receptor radioligand. ChemMedChem 4 (2), pp. 225-231. Fulltext not available.

Kühnle, Matthias, Egger, Michael, Müller, Christine, Mahringer, Anne, Bernhardt, Günther, Fricker, Gert , König, Burkhard and Buschauer, Armin (2009) Potent and selective inhibitors of breast cancer resistance protein (ABCG2) derived from the p-glycoprotein (ABCB1) modulator tariquidar. Journal of Medicinal Chemistry 52 (4), pp. 1190-1197. Fulltext not available.

Sander, Kerstin, Kottke, Tim, Tanrikulu, Yusuf, Proschak, Ewgenij, Weizel, Lilia, Schneider, Erich H. , Seifert, Roland, Schneider, Gisbert and Stark, Holger (2009) 2,4-Diaminopyrimidines as histamine H4 receptor ligands—Scaffold optimization and pharmacological characterization. Bioorganic & Medicinal Chemistry 17 (20), pp. 7186-7196. Fulltext not available.

Romagnoli, Romeo, Baraldi, Pier Giovanni, Carrion, Maria Dora , Cruz-Lopez, Olga, Lopez Cara, Carlota, Basso, Giuseppe, Viola, Giampietro , Khedr, Mohammed , Balzarini, Jan, Mahboobi, Siavosh, Sellmer, Andreas, Brancale, Andrea and Hamel, Ernest (2009) 2-Arylamino-4-Amino-5-Aroylthiazoles. “One-Pot” Synthesis and Biological Evaluation of a New Class of Inhibitors of Tubulin Polymerization. Journal of Medicinal Chemistry 52 (17), pp. 5551-5555. Fulltext not available.

Amann, Thomas, Bataille, Frauke, Spruss, Thilo, Mühlbauer, Marcus, Gäbele, Erwin, Schölmerich, Jürgen, Kiefer, Paul, Bosserhoff, Anja‐Katrin and Hellerbrand, Claus (2009) Activated hepatic stellate cells promote tumorigenicity of hepatocellular carcinoma. Cancer Science 100 (4), pp. 646-653. Fulltext not available.

Hartkorn, Andreas, Hoffmann, Florian, Ajamieh, Hussam, Vogel, Susanne, Heilmann, Jörg, Gerbes, Alexander L., Vollmar, Angelika M. and Zahler, Stefan (2009) Antioxidant Effects of Xanthohumol and Functional Impact on Hepatic Ischemia−Reperfusion Injury. Journal of Natural Products 72 (10), pp. 1741-1747. Fulltext not available.

Weiser, Barbara, Sommer, Florian, Neubauer, M., Seitz, Anna Katharina, Teßmar, Jörg , Göpferich, Achim and Blunk, Torsten (2009) Ascorbic Acid Enhances Adipogenesis of Bone Marrow-Derived Mesenchymal Stromal Cells. Cells Tissues Organs 189 (6), pp. 373-381. Fulltext not available.

Rupprecht, Korbinian, Schmidt, Christoph, Raspé, Anne, Schweda, Frank, Shipkova, Maria, Fischer, Wolfgang, Bucher, Michael, Kees, Frieder and Faerber, Lothar (2009) Bioavailability of Mycophenolate Mofetil and Enteric‐Coated Mycophenolate Sodium Is Differentially Affected by Pantoprazole in Healthy Volunteers. The Journal of Clinical Pharmacology 49 (10), pp. 1196-1201. Fulltext not available.

Heidel, Florian, Lipka, Daniel B., Mirea, Fian K., Mahboobi, Siavosh, Grundler, Rebekka, Kancha, Rama K., Duyster, Justus, Naumann, Michael , Huber, Christoph, Böhmer, Frank D. and Fischer, Thomas (2009) Bis(1H‐indol‐2‐yl)methanones are effective inhibitors of FLT3‐ITD tyrosine kinase and partially overcome resistance to PKC412A in vitro. British Journal of Haematology 144 (6), pp. 865-874. Fulltext not available.

Göttle, Martin, Geduhn, Jens, König, Burkhard , Gille, Andreas , Höcherl, Klaus and Seifert, Roland (2009) Characterization of Mouse Heart Adenylyl Cyclase. Journal of Pharmacology and Experimental Therapeutics 329 (3), pp. 1156-1165. Fulltext not available.

Wittmann, Hans-Joachim, Seifert, Roland and Strasser, Andrea (2009) Contribution of binding enthalpy and entropy to affinity of antagonist and agonist binding at human and guinea pig histamine H1-receptor. Molecular Pharmacology 76, pp. 25-37. Fulltext not available.

Bauhuber, Sonja, Hozsa, Constantin, Breunig, Miriam and Göpferich, Achim (2009) Delivery of Nucleic Acids via Disulfide-Based Carrier Systems. Advanced Materials (Weinheim, Germany) 21 (32-33), pp. 3286-3306. Fulltext not available.

Mahboobi, Siavosh, Dove, Stefan, Sellmer, Andreas, Winkler, Matthias, Eichhorn, Emerich, Pongratz, Herwig, Ciossek, Thomas, Baer, Thomas, Maier, Thomas and Beckers, Thomas (2009) Design of chimeric histone deacetylase- and tyrosine kinase-inhibitors: a series of imatinib hybrides as potent inhibitors of wild-type and mutant BCR-ABL, PDGF-Rbeta, and histone deacetylases. Journal of medicinal chemistry 52 (8), pp. 2265-79. Fulltext not available.

Vlachy, Nina, Touraud, Didier, Heilmann, Jörg and Kunz, Werner (2009) Determining the cytotoxicity of catanionic surfactant mixtures on HeLa cells. Colloids and Surfaces, B: Biointerfaces 70 (2), pp. 278-280. Fulltext not available.

Suryanarayana, Srividya, Göttle, Martin, Hübner, Melanie, Gille, Andreas , Mou, Tung-Chung, Sprang, Stephen R., Richter, Mark and Seifert, Roland (2009) Differential Inhibition of Various Adenylyl Cyclase Isoforms and Soluble Guanylyl Cyclase by 2′,3′-O-(2,4,6-Trinitrophenyl)-Substituted Nucleoside 5′-Triphosphates. Journal of Pharmacology and Experimental Therapeutics 330 (3), pp. 687-695. Fulltext not available.

Pinto, Cibele, Hübner, Melanie, Gille, Andreas , Richter, Mark, Mou, Tung-Chung, Sprang, Stephen R. and Seifert, Roland (2009) Differential interactions of the catalytic subunits of adenylyl cyclase with forskolin analogs. Biochemical Pharmacology 78 (1), pp. 62-69. Fulltext not available.

Massoumi, Ramin, Kuphal, Silke, Hellerbrand, Claus, Haas, Bodo , Wild, Peter, Spruss, Thilo, Pfeifer, Alexander, Fässler, Reinhard and Bosserhoff, Anja K. (2009) Down-regulation of CYLD expression by Snail promotes tumor progression in malignant melanoma. Journal of Experimental Medicine 206 (1), pp. 221-232. Fulltext not available.

Osten, Larissa, Kubitza, Marion, Gallagher, Anna Rachel, Kastner, Jürgen, Olbrich, Heike, Vries, Uwe, Kees, Frieder, Lelongt, Brigitte, Somlo, Stefan, Omran, Heymut and Witzgall, Ralph (2009) Doxycycline accelerates renal cyst growth and fibrosis in the pcy/pcy mouse model of type 3 nephronophthisis, a form of recessive polycystic kidney disease. Histochemistry and Cell Biology 132 (2), pp. 199-210. Fulltext not available.

Beule, Achim G. , Steinmeier, Elke, Kaftan, Holger, Biebler, Karl-Ernst, Gopferich, Achim , Wolf, Eduard and Hosemann, Werner (2009) Effects of a Dexamethasone-Releasing Stent on Osteoneogenesis in a Rabbit Model. American Journal of Rhinology & Allergy 23 (4), pp. 433-436. Fulltext not available.

Beule, A. G., Steinmeier, E., Kaftan, H., Biebler, K.-E., Göpferich, Achim, Wolf, Eva and Hosemann, W. (2009) Effects of a dexamethasone-releasing stent on osteoneogenesis in a rabbit model. American journal of rhinology & allergy 23 (4), pp. 433-436. Fulltext not available.

Schuessele, Andrea, Mayr, H., Teßmar, Jörg and Göpferich, Achim (2009) Enhanced BMP-2 performance on hydroxyapatite ceramic surfaces. Journal of Biomedical Materials Research Part A 90A (4), pp. 959-971. Fulltext not available.

Sommer, Florian, Brandl, Ferdinand, Weiser, Barbara, Teßmar, Jörg , Blunk, Torsten and Göpferich, Achim (2009) FACS as useful tool to study distinct hyalocyte populations. Experimental Eye Research 88 (5), pp. 995-999. Fulltext not available.

Šlapetová, Tereza, Šmejkal, Karel , Innocenti, Gabbriella, Dall’Acqua, Stefano, Heilmann, Jörg, Babula, Petr, Hamzová, Eva and Žemlička, Milan (2009) Glycosylated nervogenic acid derivatives from Liparis condylobulbon (Reichb.f.) leaves. Carbohydrate Research 344 (13), pp. 1770-1774. Fulltext not available.

Schneider, Erich H. , Schnell, David, Papa, Dan and Seifert, Roland (2009) High Constitutive Activity and a G-Protein-Independent High-Affinity State of the Human Histamine H4-Receptor. Biochemistry 48 (6), pp. 1424-1438. Fulltext not available.

Schneider, Erich H. and Seifert, Roland (2009) Histamine H4 receptor–RGS fusion proteins expressed in Sf9 insect cells: A sensitive and reliable approach for the functional characterization of histamine H4 receptor ligands. Biochemical Pharmacology 78 (6), pp. 607-616. Fulltext not available.

Tanrikulu, Yusuf, Proschak, Ewgenij, Werner, Tim, Geppert, Tim, Todoroff, Nickolay, Klenner, Alexander, Kottke, Tim, Sander, Kerstin, Schneider, Erich , Seifert, Roland, Stark, Holger , Clark, Timothy and Schneider, Gisbert (2009) Homology Model Adjustment and Ligand Screening with a Pseudoreceptor of the Human Histamine H4 Receptor. ChemMedChem 4 (5), pp. 820-827. Fulltext not available.

Schoenhammer, K., Petersen, H., Guethlein, F. and Göpferich, Achim (2009) Injectable in situ forming depot systems: PEG-DAE as novel solvent for improved PLGA storage stability. International Journal of Pharmaceutics 371 (1-2), pp. 33-39. Fulltext not available.

Deml, Karl-Friedrich, Beermann, S, Neumann, Detlef , Strasser, Andrea and Seifert, Roland (2009) Interactions of histamine H1-receptor agonists and antagonists with the human histamine H4-receptor. Mol Pharmacol : Molecular pharmacology 76 (5), pp. 1019-1030. Fulltext not available.

Elbakry, Asmaa, Zaky, A., Liebl, Renate, Rachel, Reinhard, Göpferich, Achim and Breunig, Miriam (2009) Layer-by-Layer Assembled Gold Nanoparticles for siRNA Delivery. Nano Letters 9 (5), pp. 2059-2064. Fulltext not available.

Elbakry, Asmaa, Zaky, Alaa, Liebl, Renate, Rachel, Reinhard, Goepferich, Achim and Breunig, Miriam (2009) Layer-by-layer assembled gold nanoparticles for siRNA delivery. Nano letters 9 (5), pp. 2059-2064. Fulltext not available.

Taha, H. M., Schmidt, J., Göttle, M., Suryanarayana, S., Shen, Y., Tang, W.-J. , Gille, A. , Geduhn, Jens, König, Burkhard , Dove, Stefan and Seifert, Roland (2009) Molecular Analysis of the Interaction of Anthrax Adenylyl Cyclase Toxin, Edema Factor, with 2'(3')-O-(N-(methyl)anthraniloyl)-Substituted Purine and Pyrimidine Nucleotides. Mol. Pharmacol. 75 (3), pp. 693-703. Fulltext not available.

Strasser, Andrea (2009) Molecular Modelling and QSAR-based design of histamine receptor ligands. Expert Opinion on Drug Discovery (4), pp. 1061-1075. Fulltext not available.

Strasser, Andrea, Wittmann, Hans-Joachim, Kunze, Marc, Elz, Sigurd and Seifert, Roland (2009) Molecular basis for the selective interaction of synthetic agonists with the human histamine H1-receptor compared with the guinea-pig H1-receptor. Mol Pharmacol : Molecular pharmacology 75, pp. 454-465. Fulltext not available.

Appel, Bernhard, Baumer, Julia, Eyrich, Daniela, Sarhan, Hatem, Taso, S., Englert, Carsten , Göpferich, Achim, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference and make_name_string expected hash reference (2009) Synergistic effects of growth and differentiation factor-5 (GDF-5) and insulin on expanded chondrocytes in a 3-D environment. Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 17 (11), pp. 1503-1512. Fulltext not available.

Egger, Michael, Maity, Prantik, Hübner, Melanie, Seifert, Roland and König, Burkhard (2009) Synthesis and pharmacological properties of new tetracyclic forskolin analogues. European Journal of Organic Chemistry 2009 (21), pp. 3613-3618. Fulltext not available.

Mannschreck, Albrecht and von Angerer, Erwin (2009) The Metolachlor Herbicide: An Exercise in Today's Stereochemistry. Journal of Chemical Education 86 (9), p. 1054. Fulltext not available.

Keller, Max, Pop, Nathalie, Hutzler, Christoph , Beck-Sickinger, Annette G., Bernhardt, Günther and Buschauer, Armin (2008) Guanidine - acylguanidine bioisosteric approach in the design of radioligands: Synthesis of a tritium-labeled N(G)-propionylargininamide ([3H]UR-MK114) as a highly potent and selective neuropeptide Y Y1 receptor antagonist. Journal of Medicinal Chemistry 51 (24), pp. 8168-8172. Fulltext not available.

Ghorai, Prasanta, Kraus, Anja, Keller, Max, Götte, Carsten, Igel, Patrick, Schneider, Erich , Schnell, David, Bernhardt, Günther, Dove, Stefan, Zabel, Manfred, Elz, Sigurd, Seifert, Roland and Buschauer, Armin (2008) Acylguanidines as bioisosteres of guanidines: N(G)-acylated imidazolylpropylguanidines, a new class of histamine H2 receptor agonists. Journal of Medicinal Chemistry 51 (22), pp. 7193-7204. Fulltext not available.

Weiss, Stefan, Keller, Max, Bernhardt, Günther, Buschauer, Armin and König, Burkhard (2008) Modular synthesis of non-peptidic bivalent NPY Y(1) receptor antagonists. Bioorganic & Medicinal Chemistry 16 (22), pp. 9858-9866. Fulltext not available.

Strasser, Andrea, Striegl, Birgit, Wittmann, Hans-Joachim and Seifert, Roland (2008) Pharmacological Profile of Histaprodifens at Four Recombinant Histamine H1 Receptor Species Isoforms. Journal of Pharmacology and Experimental Therapeutics 324, pp. 60-71. Fulltext not available.

Spangler, Corinna M., Spangler, Christian, Göttle, Martin, Shen, Yuequan, Tang, Wei-Jen , Seifert, Roland and Schäferling, Michael (2008) A fluorimetric assay for real-time monitoring of adenylyl cyclase activity based on terbium norfloxacin. Analytical Biochemistry 381 (1), pp. 86-93. Fulltext not available.

Pinto, Cibele, Papa, Dan, Hübner, Melanie, Mou, Tung-Chung, Lushington, Gerald H. and Seifert, Roland (2008) Activation and Inhibition of Adenylyl Cyclase Isoforms by Forskolin Analogs. Journal of Pharmacology and Experimental Therapeutics 325 (1), pp. 27-36. Fulltext not available.

Koelwel, C., Rothschenk, Stefan, Fuchs-Koelwel, B., Gabler, B., Lohmann, C. and Göpferich, Achim (2008) Alginate inserts loaded with epidermal growth factor for the treatment of keratoconjunctivitis sicca. Pharmaceutical Development and Technology 13 (3), pp. 221-231. Fulltext not available.

Brem, T, Ankli, A, Klier, B, Heilmann, J and Franz, G (2008) Analysis of Coptis sp., for the purpose of establishing a monograph draft proposal for the German Pharmacopoeia. Planta Medica 74 (09). Fulltext not available.

Vogel, Susanne, Kaufmann, Doris, Pojarová, Michaela, Müller, Christine, Pfaller, Tobias, Kühne, Sybille, Bednarski, Patrick J. and Angerer, Erwin von (2008) Aroyl hydrazones of 2-phenylindole-3-carbaldehydes as novel antimitotic agents. Bioorganic & Medicinal Chemistry 16 (12), pp. 6436-6447. Fulltext not available.

Reintjes, T., Tessmar, J. and Göpferich, A. (2008) Biomimetic polymers to control cell adhesion. Journal of Drug Delivery Science and Technology 18 (1), pp. 15-24. Fulltext not available.

Kutta, Roger J., Hofinger, Edith S. A., Preuss, Hendrik, Bernhardt, Günther and Dick, Bernhard (2008) Blue-light induced interaction of LOV domains from Chlamydomonas reinhardtii. Chembiochem : a European journal of chemical biology 9 (12), pp. 1931-1938. Fulltext not available.

Wagenlehner, F.M.E., Kees, F., Weidner, W., Wagenlehner, C. and Naber, K.G. (2008) Concentrations of moxifloxacin in plasma and urine, and penetration into prostatic fluid and ejaculate, following single oral administration of 400mg to healthy volunteers. International Journal of Antimicrobial Agents 31 (1), pp. 21-26. Fulltext not available.

Fang, Lei, Kraus, Birgit, Lehmann, Jochen, Heilmann, Joerg, Zhang, Yihua and Decker, Michael (2008) Design and synthesis of tacrine–ferulic acid hybrids as multi-potent anti-Alzheimer drug candidates. Bioorganic & Medicinal Chemistry Letters 18 (9), pp. 2905-2909. Fulltext not available.

Decker, Michael, Kraus, Birgit and Heilmann, Jörg (2008) Design, synthesis and pharmacological evaluation of hybrid molecules out of quinazolinimines and lipoic acid lead to highly potent and selective butyrylcholinesterase inhibitors with antioxidant properties. Bioorganic & Medicinal Chemistry 16 (8), pp. 4252-4261. Fulltext not available.

Nickl, Kathrin, Gardner, Eric E. , Geiger, Sarah, Heilmann, Jörg and Seifert, Roland (2008) Differential coupling of the human cannabinoid receptors hCB1R and hCB2R to the G-protein Gαi2β1γ2. Neuroscience Letters 447 (1), pp. 68-72. Fulltext not available.

Weitl, Nina and Seifert, Roland (2008) Distinct Interactions of Human β1- and β2-Adrenoceptors with Isoproterenol, Epinephrine, Norepinephrine, and Dopamine. Journal of Pharmacology and Experimental Therapeutics 327 (3), pp. 760-769. Fulltext not available.

Hubensack, Martina, Müller, Christine, Höcherl, Höcherl, Fellner, Stephan, Spruss, Thilo, Bernhardt, Günther and Buschauer, Armin (2008) Effect of the ABCB1 modulators elacridar and tariquidar on the distribution of paclitaxel in nude mice. Journal of Cancer Research and Clinical Oncology 134 (5), pp. 597-607. Fulltext restricted.

Beule, A. G., Scharf, C., Biebler, K.-E., Göpferich, Achim, Steinmeier, E., Wolf, E., Hosemann, W. and Kaftan, H. (2008) Effects of Topically Applied Dexamethasone on Mucosal Wound Healing Using a Drug-Releasing Stent. The Laryngoscope 118 (11), pp. 2073-2077. Fulltext not available.

Beule, Achim G. , Scharf, Christian , Biebler, Karl‐Ernst, Göpferich, Achim , Steinmeier, Elke, Wolf, Eduard, Hosemann, Werner and Kaftan, Holger (2008) Effects of Topically Applied Dexamethasone on Mucosal Wound Healing Using a Drug‐Releasing Stent. The Laryngoscope 118 (11), pp. 2073-2077. Fulltext not available.

Kleemann, Patrick, Papa, Dan, Vigil-Cruz, Sandy and Seifert, Roland (2008) Functional reconstitution of the human chemokine receptor CXCR4 with Gi/Go-proteins in Sf9 insect cells. Naunyn-Schmiedeberg's Archives of Pharmacology 378 (3), pp. 261-274. Fulltext not available.

Sommer, Florian, Pollinger, Klaus, Brandl, Ferdinand, Weiser, Barbara, Teßmar, Jörg , Blunk, Torsten and Göpferich, Achim (2008) Hyalocyte proliferation and ECM accumulation modulated by bFGF and TGF-β1. Graefe's Archive for Clinical and Experimental Ophthalmology 246 (9), pp. 1275-1284. Fulltext not available.

Weiser, Barbara, Prantl, Lukas, Schubert, Thomas E. O., Zellner, J. , Fischbach-Teschl, Claudia, Spruss, Thilo, Seitz, Anna Katharina, Teßmar, Jörg , Göpferich, Achim and Blunk, Torsten (2008) In Vivo Development and Long-Term Survival of Engineered Adipose Tissue Depend on In Vitro Precultivation Strategy. Tissue Engineering Part A 14 (2), pp. 275-284. Fulltext not available.

Barbič, M, Heilmann, J, Melzig, MF and Jürgenliemk, G (2008) Inhibition of ICAM-1 expression and elastase by an extract and fractions from the roots of Ruscus aculeatus. Planta Medica 74 (09). Fulltext not available.

Mahboobi, Siavosh, Sellmer, Andreas, Eswayah, Asma, Elz, Sigurd, Uecker, Andrea and Böhmer, Frank-D. (2008) Inhibition of PDGFR tyrosine kinase activity by a series of novel N-(3-(4-(pyridin-3-yl)-1H-imidazol-2-ylamino)phenyl)amides: a SAR study on the bioisosterism of pyrimidine and imidazole. European journal of medicinal chemistry 43 (7), pp. 1444-1453. Fulltext not available.

Göpferich, Achim (2008) Interactive polymers for pharmaceutical and biomedical applications. European journal of pharmaceutics and biopharmaceutics 68 (1), p. 1. Fulltext not available.

Hofinger, Edith S. A., Hoechstetter, Julia, Oettl, Martin, Bernhardt, Günther and Buschauer, Armin (2008) Isoenzyme-specific differences in the degradation of hyaluronic acid by mammalian-type hyaluronidases. Glycoconjugate Journal 25 (2), pp. 101-109. Fulltext not available.

Strasser, Andrea, Wittmann, Hans-Joachim and Seifert, Roland (2008) Ligand-specific contribution of the N-terminus and E2-loop to pharmacological properties of the histamine H1-receptor. J Pharmacol Exp Ther : The journal of pharmacology and experimental therapeutics 326 (3), pp. 783-791. Fulltext not available.

Breunig, Miriam , Hosza, C., Lungwitz, Uta, Watanabe, K., Umeda, I., Kato, H. and Göpferich, Achim (2008) Mechanistic investigation of poly(ethylene imine)-based siRNA delivery: Disulfide bonds boost intracellular release of the cargo. Journal of Controlled Release 130 (1), pp. 57-63. Fulltext not available.

Lungwitz, Uta, Breunig, Miriam , Liebl, Renate, Blunk, Torsten and Göpferich, Achim (2008) Methoxy poly(ethylene glycol) – Low molecular weight linear polyethylenimine-derived copolymers enable polyplex shielding. European Journal of Pharmaceutics and Biopharmaceutics 69 (1), pp. 134-148. Fulltext not available.

Vogel, Susanne, Ohmayer, Susanne, Brunner, Gabi and Heilmann, Jörg (2008) Natural and non-natural prenylated chalcones: Synthesis, cytotoxicity and anti-oxidative activity. Bioorganic & Medicinal Chemistry 16 (8), pp. 4286-4293. Fulltext not available.

Hezinger, A.F.E., Teßmar, J. and Göpferich, A. (2008) Polymer coating of quantum dots – A powerful tool toward diagnostics and sensorics. European Journal of Pharmaceutics and Biopharmaceutics 68 (1), pp. 138-152. Fulltext not available.

Breunig, M. , Bauer, S. and Goepferich, A. (2008) Polymers and nanoparticles: Intelligent tools for intracellular targeting? European Journal of Pharmaceutics and Biopharmaceutics 68 (1), pp. 112-128. Fulltext not available.

Hild, W.A., Breunig, M. and Goepferich, A. (2008) Quantum dots – Nano-sized probes for the exploration of cellular and intracellular targeting. European Journal of Pharmaceutics and Biopharmaceutics 68 (2), pp. 153-168. Fulltext not available.

Dai, Jisen, Jian, Jinlong, Bosland, Maarten, Frenkel, Krystyna, Bernhardt, Günther and Huang, Xi (2008) Roles of hormone replacement therapy and iron in proliferation of breast epithelial cells with different estrogen and progesterone receptor status. Breast (Edinburgh, Scotland) 17 (2), pp. 172-179. Fulltext not available.

Vlachy, N., Merle, C., Touraud, D., Schmidt, J., Talmon, Y., Heilmann, J. and Kunz, W. (2008) Spontaneous Formation of Bilayers and Vesicles in Mixtures of Single-Chain Alkyl Carboxylates: Effect of pH and Aging and Cytotoxicity Studies. Langmuir 24 (18), pp. 9983-9988. Fulltext not available.

Kiewitz, Sebastian D., Kakizawa, Taeko, Kiso, Yoshiaki and Cabrele, Chiara (2008) Switching from the unfolded to the folded state of the helix‐loop‐helix domain of the Id proteins based on the O‐acyl isopeptide method. Journal of Peptide Science 14 (11), pp. 1209-1215. Fulltext not available.

Egger, M., Pellett, P., Nickl, K., Geiger, S., Graetz, S., Seifert, R., Heilmann, J. and König, B. (2008) Synthesis and Cannabinoid Receptor Activity of Ketoalkenes from Echinacea pallida and Non-natural Analogues. Chem. Eur. J. 14, 10978 - 10984. Fulltext not available.

Vogel, Susanne and Heilmann, Jörg (2008) Synthesis, Cytotoxicity, and Antioxidative Activity of Minor Prenylated Chalcones from Humulus lupulus. Journal of Natural Products 71 (7), pp. 1237-1241. Fulltext not available.

Hellerbrand, C, Amann, T, Schlegel, J, Wild, P, Bataille, F, Spruss, T, Hartmann, A and Bosserhoff, A-K (2008) The novel gene MIA2 acts as a tumour suppressor in hepatocellular carcinoma. Gut 57 (2), pp. 243-251. Fulltext not available.

Schulte-Mattler, Wilhelm J (2008) Use of Botulinum Toxin A in Adult Neurological Disorders. CNS Drugs 22 (9), pp. 725-738. Fulltext not available.

Schmidtko, Achim, Gao, Wei, König, Peter, Heine, Sandra, Motterlini, Roberto , Ruth, Peter, Schlossmann, Jens , Koesling, Doris, Niederberger, Ellen, Tegeder, Irmgard , Friebe, Andreas and Geisslinger, Gerd (2008) cGMP Produced by NO-Sensitive Guanylyl Cyclase Essentially Contributes to Inflammatory and Neuropathic Pain by Using Targets Different from cGMP-Dependent Protein Kinase I. The Journal of Neuroscience 28 (34), pp. 8568-8576. Fulltext not available.

Göttle, Martin, Dove, Stefan, Steindel, Phillip, Shen, Yuequan, Tang, Wei-Jen , Geduhn, Jens, König, Burkhard and Seifert, Roland (2007) Molecular Analysis of the Interaction of Bordetella pertussis Adenylyl Cyclase with Fluorescent Nucleotides. Molecular Pharmacology 72 (3), pp. 526-535.

Lorenz, Veronika, Pinto, Cibele S. and Seifert, Roland (2007) Complex changes in ecto-nucleoside 5'-triphosphate diphosphohydrolase expression in hypoxanthine phosphoribosyl transferase deficiency. Neuroscience Letters 420 (1), pp. 6-11.

Wang, Jenna L., Guo, Jian-Xin, Zhang, Qi-Yuan, Wu, Jay J.-Q., Seifert, Roland and Lushington, Gerald H. (2007) A conformational transition in the adenylyl cyclase catalytic site yields different binding modes for ribosyl-modified
and unmodified nucleotide inhibitors. Bioorganic & Medicinal Chemistry 15 (8), pp. 2993-3002.

Preuss, Hendrik, Ghorai, Prasanta, Kraus, Anja, Dove, Stefan, Buschauer, Armin and Seifert, Roland (2007) Constitutive Activity and Ligand Selectivity of Human,
Guinea Pig, Rat, and Canine Histamine H₂ Receptors. Journal of Pharmacology and Experimental Therapeutics 321 (3), pp. 983-995.

Preuss, Hendrik, Ghorai, Prasanta, Kraus, Anja, Dove, Stefan, Buschauer, Armin and Seifert, Roland (2007) Mutations of Cys-17 and Ala-271 in the Human Histamine H₂
Receptor Determine the Species Selectivity of Guanidine-Type Agonists and Increase Constitutive Activity. Journal of Pharmacology and Experimental Therapeutics 321 (3), pp. 975-982.

Nickl, K, Seifert, R and Heilmann, J (2007) Analysis of natural and synthetic cannabinoid receptor ligands via [32P]GTPase assay. Planta Medica 73 (09). Fulltext not available.

Kaufmann, Doris, Pojarová, Michaela, Vogel, Susanne, Liebl, Renate, Gastpar, Robert, Gross, Dietmar, Nishino, Tsuyuki, Pfaller, Tobias and Angerer, Erwin von (2007) Antimitotic activities of 2-phenylindole-3-carbaldehydes in human breast cancer cells. Bioorganic & medicinal chemistry 15 (15), pp. 5122-36. Fulltext not available.

Sommer, Florian, Kobuch, Karin, Brandl, Ferdinand, Wild, Brigitte, Framme, Carsten, Weiser, Barbara, Tessmar, Joerg , Gabel, Veit-Peter, Blunk, Torsten and Goepferich, Achim (2007) Ascorbic Acid Modulates Proliferation and Extracellular Matrix Accumulation of Hyalocytes. Tissue Engineering 13 (6), pp. 1281-1289. Fulltext not available.

Englert, Carsten , Blunk, Torsten, Müller, Rainer , Schulze, S., Baumer, Julia, Fierlbeck, J., Heid, I., Nerlich, Michael and Hammer, J. (2007) Bonding of articular cartilage utilising a combination of biochemical degradation and surface cross-linking. Arthritis Research & Therapy 9 (3), R47.

Breunig, Miriam , Lungwitz, Uta, Liebl, Renate and Goepferich, Achim (2007) Breaking up the correlation between efficacy and toxicity for nonviral gene delivery. Proceedings of the National Academy of Sciences 104 (36), pp. 14454-14459. Fulltext not available.

Matzdorf, Corina, Kurtz, A. and Höcherl, Klaus (2007) COX-2 activity determines the level of renin expression but is dispensable for acute upregulation of renin expression in rat kidneys. American Journal of Physiology-Renal Physiology 292 (6), F1782-F1790. Fulltext not available.

Langgartner, J., Lehn, N., Glück, T., Herzig, H. and Kees, F. (2007) Comparison of the Pharmacokinetics of Piperacillin and Sulbactam during Intermittent and Continuous Intravenous Infusion. Chemotherapy 53 (5), pp. 370-377. Fulltext not available.

Koennings, Stephanie, Tessmar, Joerg , Blunk, Torsten and Göpferich, Achim (2007) Confocal Microscopy for the Elucidation of Mass Transport Mechanisms Involved in Protein Release from Lipid-based Matrices. Pharmaceutical Research 24 (7), pp. 1325-1335. Fulltext not available.

Tessmar, Joerg K. and Göpferich, Achim M. (2007) Customized PEG‐Derived Copolymers for Tissue‐Engineering Applications. Macromolecular Bioscience 7 (1), pp. 23-39. Fulltext not available.

Karioti, Anastasia , Skopeliti, Margarita, Tsitsilonis, Ourania, Heilmann, Jörg and Skaltsa, Helen (2007) Cytotoxicity and immunomodulating characteristics of labdane diterpenes from Marrubium cylleneum and Marrubium velutinum. Phytochemistry 68 (11), pp. 1587-1594. Fulltext not available.

Brennauer, Albert, Keller, Max, Freund, Matthias, Bernhardt, Günther and Buschauer, Armin (2007) Decomposition of 1-(ω-aminoalkanoyl)guanidines under alkaline conditions. Tetrahedron Letters 48 (39), pp. 6996-6999. Fulltext not available.

Ziemek, Ralf, Schneider, Erich , Kraus, Anja, Cabrele, Chiara , Beck-Sickinger, Annette G., Bernhardt, Günther and Buschauer, Armin (2007) Determination of affinity and activity of ligands at the human neuropeptide Y Y4 receptor by flow cytometry and aequorin luminescence. Journal of Receptors and Signal Transduction 27 (4), pp. 217-233. Fulltext not available.

Koeber, R, Bader, W, Jahner, T, Melchner, D and Haen, E (2007) Determination of rivastigmine in serum using solid phase extraction and high perfomance liquid chromatography coupled to UV detection technique for routine medical analysis. Pharmacopsychiatry 40 (05). Fulltext not available.

Maschke, Angelika, Becker, Christian, Eyrich, Daniela, Kiermaier, Josef, Blunk, Torsten and Göpferich, Achim (2007) Development of a spray congealing process for the preparation of insulin-loaded lipid microparticles and characterization thereof. European Journal of Pharmaceutics and Biopharmaceutics 65 (2), pp. 175-187. Fulltext not available.

Xie, Sheng-Xue, Schalkhausser, Fabian, Ye, Qi-Zhuang, Seifert, Roland and Buschauer, Armin (2007) Effects of Impromidine- and Arpromidine-Derived Guanidines on Recombinant Human and Guinea Pig Histamine H₁ and H₂ Receptors. Archiv der Pharmazie 340 (1), pp. 9-16.

Bradacs, G and Heilmann, J (2007) Ethnopharmacological and phytochemical studies of medicinal plants from Vanuatu. Planta Medica 73 (09). Fulltext not available.

Dreiseitel, Andrea, Schreier, P., Hajak, Göran and Sand, P. G. (2007) Flavonoid-drug interactions: effects of anthocyanins and anthocyanidins on CYP2D6. Pharmacopsychiatry 40 (05), A179. Fulltext not available.

Rottlaender, Dennis, Matthes, Jan, Vatner, Stephen F., Seifert, Roland and Herzig, Stefan (2007) Functional Adenylyl Cyclase Inhibition in Murine
Cardiomyocytes by 2'(3')-O-(N-Methylanthraniloyl)-Guanosine
5'-[γ-Thio]triphosphate. Journal of Pharmacology and Experimental Therapeutics 321 (2), pp. 608-615.

Rothhammer, T, Bataille, F, Spruss, T, Eissner, G and Bosserhoff, A-K (2007) Functional implication of BMP4 expression on angiogenesis in malignant melanoma. Oncogene 26 (28), pp. 4158-4170. Fulltext not available.

Schlegel, Birgit, Laggner, Christian, Meier, Rene , Langer, Thierry , Schnell, David, Seifert, Roland, Stark, Holger , Höltje, Hans-Dieter and Sippl, Wolfgang (2007) Generation of a homology model of the human histamine H₃ receptor for ligand docking and pharmacophore-based screening. Journal of Computer-Aided Molecular Design.

Romagnoli, Romeo, Baraldi, Pier Giovanni, Carrion, Maria Dora , Cruz-Lopez, Olga, Preti, Delia, Tabrizi, Mojgan Aghazadeh, Fruttarolo, Francesca, Heilmann, Jörg, Bermejo, Jaime and Estévez, Francisco (2007) Hybrid molecules containing benzo[4,5]imidazo[1,2-d][1,2,4]thiadiazole and α-bromoacryloyl moieties as potent apoptosis inducers on human myeloid leukaemia cells. Bioorganic & Medicinal Chemistry Letters 17 (10), pp. 2844-2848. Fulltext not available.

Kraus, Birgit, Wolff, Horst, Heilmann, Jörg and Elstner, Erich F. (2007) Influence of Hypericum perforatum extract and its single compounds on amyloid-β mediated toxicity in microglial cells. Life Sciences 81 (11), pp. 884-894. Fulltext not available.

Bergmann, Antje, Teßmar, Jörg and Owen, Anthony (2007) Influence of electron irradiation on the crystallisation, molecular weight and mechanical properties of poly-(R)-3-hydroxybutyrate. Journal of Materials Science 42 (11), pp. 3732-3738. Fulltext not available.

Koennings, S., Berié, A., Tessmar, J. , Blunk, T. and Goepferich, A. (2007) Influence of wettability and surface activity on release behavior of hydrophilic substances from lipid matrices. Journal of Controlled Release 119 (2), pp. 173-181. Fulltext not available.

Mahboobi, Siavosh, Uecker, Andrea, Cénac, Christophe, Sellmer, Andreas, Eichhorn, Emerich, Elz, Sigurd, Böhmer, Frank-D. and Dove, Stefan (2007) Inhibition of FLT3 and PDGFR tyrosine kinase activity by bis(benzo[b]furan-2-yl)methanones. Bioorganic & Medicinal Chemistry 15 (5), pp. 2187-2197. Fulltext not available.

Müller, Christine, Gross, Dietmar, Sarli, Vasiliki, Gartner, Michael, Giannis, Athanassios, Bernhardt, Günther and Buschauer, Armin (2007) Inhibitors of kinesin Eg5: antiproliferative activity of monastrol analogues against human glioblastoma cells. Cancer Chemotherapy and Pharmacology 59 (2), pp. 157-164. Fulltext not available.

Gousiadou, C, Karioti, A, Heilmann, J and Skaltsa, H (2007) Iridoids from Scutellaria albida ssp. albida. Planta Medica 73 (09). Fulltext not available.

Gousiadou, Chrysoula, Karioti, Anastasia , Heilmann, Jörg and Skaltsa, Helen (2007) Iridoids from Scutellaria albida ssp. albida. Phytochemistry 68 (13), pp. 1799-1804. Fulltext not available.

Zoriy, Myroslav, Matusch, Andreas, Spruss, Thilo and Becker, J. Sabine (2007) Laser ablation inductively coupled plasma mass spectrometry for imaging of copper, zinc, and platinum in thin sections of a kidney from a mouse treated with cis-platin. International Journal of Mass Spectrometry 260 (2-3), pp. 102-106. Fulltext not available.

Eyrich, Daniela, Brandl, Ferdinand, Appel, Bernhard, Wiese, Hinrich , Maier, Gerhard, Wenzel, Magdalene, Staudenmaier, Rainer, Goepferich, Achim and Blunk, Torsten (2007) Long-term stable fibrin gels for cartilage engineering. Biomaterials 28 (1), pp. 55-65. Fulltext not available.

Suryanarayana, Srividya, Tang, Wei‐Jen, Lushington, Gerald, Richter, Mark and Seifert, Roland (2007) MANT nucleotides as probes for analysis of Edema Factor, a bacterial Adenylyl Cyclase toxin. The FASEB Journal 21 (6). Fulltext not available.

Tessmar, Joerg K. and Göpferich, Achim M. (2007) Matrices and scaffolds for protein delivery in tissue engineering. Advanced Drug Delivery Reviews 59 (4-5), pp. 274-291. Fulltext not available.

Eichhammer, P., Landgrebe, M., Langguth, Berthold, Sand, P. and Hajak, Göran (2007) Neurophysiological aspects of typical and atypical neuroleptic agents. Pharmacopsychiatry 40 (05). Fulltext not available.

Math´e, A.A., Gruber, S.H.M, El Khoury, A., Beiderbeck, D., Neumann, I.D. and Landgraf, R. (2007) P.4.b.002 Brain biochemistry markers differentiate between animal models of anxiety and depression. European Neuropsychopharmacology 17, S510-S511. Fulltext not available.

Schertl, Sabine, Hartmann, Rolf W., Batzl-Hartmann, Christine, Spruss, Thilo, Maucher, Anton, Angerer, Erwin von, Schiller, Claus D., Schneider, Martin R., Gust, Ronald and Schönenberger, Helmut (2007) Platinum(II) complexes interfering with testicular steroid biosynthesis: drugs for the therapy of advanced or recurrent prostate cancers? Preclinical studies. Journal of Cancer Research and Clinical Oncology 133 (3), pp. 153-167. Fulltext not available.

Preuss, Hendrik, Ghorai, Prasanta, Kraus, Anja, Dove, Stefan, Buschauer, Armin and Seifert, Roland (2007) Point Mutations in the Second Extracellular Loop of the Histamine H2 Receptor do not affect the Species-Selective Activity of Guanidine-Type Agonists. Naunyn Schmiedebergs Arch. Pharmacol. 376 (4), pp. 253-264. Fulltext restricted.

Brandl, F., Henke, M., Rothschenk, S., Gschwind, R. M. , Breunig, M. , Tessmar, J. and Goepferich, Achim (2007) Poly(ethylene glycol) based hydrogels for intraocular applications. Advanced Engineering Materials 9 (12), pp. 1141-1149. Fulltext not available.

Neuner, T, Schmid, R and Spiessl, H (2007) Problems related to psychopharmacological treatment: A risk factor of inpatient suicidal behaviour? Pharmacopsychiatry 40 (05). Fulltext not available.

Brandl, Ferdinand, Sommer, Florian and Goepferich, Achim (2007) Rational design of hydrogels for tissue engineering: Impact of physical factors on cell behavior. Biomaterials 28 (2), pp. 134-146. Fulltext not available.

Hofinger, Edith S. A., Spickenreither, Martin, Oschmann, Jan, Bernhardt, Günther, Rudolph, Rainer and Buschauer, Armin (2007) Recombinant human hyaluronidase Hyal-1: insect cells versus E. coli as expression system and identification of low molecular weight inhibitors. Glycobiology 17 (4), pp. 444-453. Fulltext not available.

Weber, Silke, Bernhard, Dominik, Lukowski, Robert, Weinmeister, Pascal, Wörner, René, Wegener, Jörg W., Valtcheva, Nadejda, Feil, Susanne , Schlossmann, Jens , Hofmann, Franz and Feil, Robert (2007) Rescue of cGMP Kinase I Knockout Mice by Smooth Muscle–Specific Expression of Either Isozyme. Circulation Research 101 (11), pp. 1096-1103. Fulltext not available.

Saroglou, Vasiliki, Karioti, Anastasia , Heilmann, Jörg, Kypriotakis, Zacharias and Skaltsa, Helen (2007) Sesquiterpene Lactones from Anthemis melanolepis. Helvetica Chimica Acta 90 (1), pp. 171-175. Fulltext not available.

Schmid, R, Mehlsteibl, D, Schielein, T, Hübner-Liebermann, B and Spiessl, H (2007) Side effects and non-compliance as causes of inpatient suicides – different assessments of caregivers and professionals. Pharmacopsychiatry 40 (05). Fulltext not available.

Hacker, Michael , Ringhofer, Michael, Appel, Bernhard, Neubauer, Markus, Vogel, Thomas, Young, Simon , Mikos, Antonios G., Blunk, Torsten, Göpferich, Achim and Schulz, Michaela B. (2007) Solid lipid templating of macroporous tissue engineering scaffolds. Biomaterials 28 (24), pp. 3497-3507. Fulltext not available.

Schneider, Erich , Keller, Max, Brennauer, Albert, Hoefelschweiger, Bianca K., Gross, Dietmar, Wolfbeis, Otto S. , Bernhardt, Günther and Buschauer, Armin (2007) Synthesis and Characterization of the First Fluorescent Nonpeptide NPY Y1 Receptor Antagonist. ChemBioChem 8 (16), pp. 1981-1988. Fulltext restricted.

Murphy, Matthew B., Hartgerink, Jeffrey D. , Goepferich, Achim and Mikos, Antonios G. (2007) Synthesis and in Vitro Hydroxyapatite Binding of Peptides Conjugated to Calcium-Binding Moieties. Biomacromolecules 8 (7), pp. 2237-2243. Fulltext not available.

Vogel, S and Heilmann, J (2007) Synthesis of prenylated hop chalcones and evaluation of their cytotoxic activity. Planta Medica 73 (09). Fulltext not available.

Egger, Michael, Li, Xuqin, Müller, Christine, Bernhardt, Günther, Buschauer, Armin and König, Burkhard (2007) Tariquidar analogues: synthesis by Cu(I)-catalysed N/O–aryl coupling and inhibitory activity against the ABCB1 transporter. European Journal of Organic Chemistry 2007 (16), pp. 2643-2649. Fulltext not available.

Hajak, Göran, Langguth, Berthold, Landgrebe, M., Sand, P. and Eichhammer, Peter (2007) Thalamic gating, schizophrenia and antipsychotic treatment – an investigation with TMS. Pharmacopsychiatry 40 (05), A077. Fulltext not available.

Faerber, Lothar, Drechsler, Sabine, Ladenburger, Stephan, Gschaidmeier, Harald and Fischer, Wolfgang (2007) The neuronal 5-HT3 receptor network after 20 years of research — Evolving concepts in management of pain and inflammation. European Journal of Pharmacology 560 (1), pp. 1-8. Fulltext not available.

Hader, A, Kirchheiner, J, Jahner, T and Haen, E (2007) Therapeutic Drug Monitoring in Psychiatry – Genotyping amends clinical pharmacological comments. Pharmacopsychiatry 40 (05). Fulltext not available.

Koennings, S., Sapin, A., Blunk, T., Menei, P. and Goepferich, A. (2007) Towards controlled release of BDNF — Manufacturing strategies for protein-loaded lipid implants and biocompatibility evaluation in the brain. Journal of Controlled Release 119 (2), pp. 163-172. Fulltext not available.

Mannschreck, Albrecht, Kiesswetter, Roland and von Angerer, Erwin (2007) Unequal Activities of Enantiomers via Biological Receptors: Examples of Chiral Drug, Pesticide, and Fragrance Molecules. Journal of Chemical Education 84 (12), p. 2012. Fulltext not available.

Heilmann, Jörg (2007) Wirkstoffe auf Basis biologisch aktiver Naturstoffe. Chemie in unserer Zeit 41 (5), pp. 376-389. Fulltext not available.

Pojarová, Michaela, Kaufmann, Doris, Gastpar, Robert, Nishino, Tsuyuki, Reszka, Przemyslaw, Bednarski, Patrick J. and Angerer, Erwin von (2007) [(2-Phenylindol-3-yl)methylene]propanedinitriles inhibit the growth of breast cancer cells by cell cycle arrest in G(2)/M phase and apoptosis. Bioorganic & medicinal chemistry 15 (23), pp. 7368-7379. Fulltext not available.

Amann, T., Spruss, T., Bataille, F., Liedtke, C., Muhlbauer, M., Trautwein, C., Bosserhoff, A.K. and Hellerbrand, C. (2007) [69] IDENTIFICATION OF FIBROBLAST GROWTH FACTOR RECEPTOR 2IIIB (FGFR2IIIB) AS TUMOR SUPPRESSOR IN HEPATOCANCEROGENESIS. Journal of Hepatology 46, S31. Fulltext not available.

Kees, Frieder, Bucher, Michael, Schweda, Frank, Gschaidmeier, Harald, Burhenne, Juergen , Mikus, Gerd and Faerber, Lothar (2006) Comparative bioavailability of the microemulsion formulation of cyclosporine (Neoral) with a generic dispersion formulation (Cicloral) in young healthy male volunteers. Therapeutic drug monitoring 28 (3), pp. 312-320. Fulltext restricted.

Xie, Sheng-Xue, Kraus, Anja, Ghorai, Prasanta, Ye, Qi-Zhuang, Elz, Sigurd, Buschauer, Armin and Seifert, Roland (2006) N1-(3-Cyclohexylbutanoyl)-N2-[3-(1H-imidazol-4-
yl)propyl]guanidine (UR-AK57), a Potent Partial Agonist for the Human Histamine H1- and H2- Receptors. Journal of Pharmacology and Experimental Therapeutics 317 (3), pp. 1262-1268. Fulltext restricted.

Wabnitz, Tobias C., Rizzo, Simona , Götte, Carsten, Buschauer, Armin, Benincori, Tiziana and Reiser, Oliver (2006) Enantioselective hydrogenation of diaryl-substituted a,b-unsaturated nitriles. Tetrahedron Letters 47 (22), pp. 3733-3736. Fulltext not available.

Bucher, Michael, Kees, Frieder K., Messmann, Barbara, Lunz, Dirk, Rath, Stephan, Zelenka, Marek, Schlitt, Hans J. and Hobbhahn, Jonny (2006) Prostaglandin I2 release following mesenteric traction during abdominal surgery is mediated by cyclooxygenase-1. European journal of pharmacology 536 (3), pp. 296-300. Fulltext restricted.

Patil, Rameshwar, Elz, Sigurd and Reiser, Oliver (2006) Side-chain modified analogues of histaprodifen: Asymmetric synthesis and histamine H₁-receptor activity. Bioorg. Med. Chem. Lett. 16 (3), pp. 672-676. Fulltext not available.

Xie, Sheng-Xue, Ghorai, Prasanta, Ye, Qi-Zhuang, Buschauer, Armin and Seifert, Roland (2006) Probing Ligand-Specific Histamine H1- and H2-Receptor
Conformations with NG-Acylated Imidazolylpropylguanidines. The Journal of Pharmacology and Experimental Therapeutics 317 (1), pp. 139-146. Fulltext restricted.

Mahboobi, Siavosh, Eichhorn, Emerich, Popp, Alfred, Sellmer, Andreas, Elz, Sigurd and Möllmann, Ute (2006) 3-Bromo-4-(1H-3-indolyl)-2,5-dihydro-1H-2,5-pyrroledione derivatives as new lead compounds for antibacterially active substances. European Journal of Medicinal Chemistry 41 (2), pp. 176-191. Fulltext not available.

Hellerbrand, C., Amann, T., Schlegel, J., Spruss, T., Bataille, F., Hartmann, A., Mühlbauer, M., Schölmerich, J. and Bosserhoff, A.K. (2006) 98 The novel gene MIA2 promotes progression of hepatocellular carcinoma. Journal of Hepatology 44, S43. Fulltext not available.

Schneider, Erich , Mayer, Matthias, Ziemek, Ralf, Li, Liantao, Hutzler, Christoph , Bernhardt, Günther and Buschauer, Armin (2006) A Simple and Powerful Flow Cytometric Method for the Simultaneous Determination of Multiple Parameters at G-Protein-coupled Receptor Subtypes. ChemBioChem 7 (9), pp. 1400-1409. Fulltext not available.

Kaftan, H., Eyrich, D., Schindler, E., Göpferich, A. and Hosemann, W. (2006) Behandlung von Trommelfellperforationen mit Fibringel. HNO 54 (12), pp. 943-946. Fulltext not available.

Guse, C., Koennings, S., Maschke, A., Hacker, M. , Becker, C., Schreiner, S., Blunk, T., Spruss, T. and Goepferich, A. (2006) Biocompatibility and erosion behavior of implants made of triglycerides and blends with cholesterol and phospholipids. International Journal of Pharmaceutics 314 (2), pp. 153-160. Fulltext not available.

Fischer, Thomas, Bohmer, Frank D., Huber, Christoph, Dove, Stefan, Breitenbucher, Frank, Mirea, Fian K. and Heidel, Florian (2006) Bis(1H-indol-2yl)methanones Are Effective Inhibitors of Mutated FLT3 Tyrosine Kinase, Overcome Resistance to PKC412A In Vitro and Show Synergy with Chemotherapy. Blood 108 (11), p. 1369. Fulltext not available.

Mou, Tung-Chung, Gille, Andreas , Suryanarayana, Srividya, Richter, Mark, Seifert, Roland and Sprang, Stephen R. (2006) Broad Specificity of Mammalian Adenylyl Cyclase for Interaction with 2′,3′-Substituted Purine- and Pyrimidine Nucleotide Inhibitors. Molecular Pharmacology 70 (3), pp. 878-886. Fulltext not available.

Pinto, Cibele S. and Seifert, Roland (2006) Decreased GTP‐stimulated adenylyl cyclase activity in HPRT‐deficient human and mouse fibroblast and rat B103 neuroblastoma cell membranes. Journal of Neurochemistry 96 (2), pp. 454-459. Fulltext not available.

Rigden, Daniel J. , Botzki, Alexander , Nukui, Masatoshi, Mewbourne, R. Brandon, Lamani, Ejvis, Braun, Stephan, von Angerer, Erwin, Bernhardt, Günther, Dove, Stefan, Buschauer, Armin and Jedrzejas, Mark J. (2006) Design of new benzoxazole-2-thione derived inhibitors of Streptococcus pneumoniae hyaluronan lyase: structure of a complex with a 2-phenylindole. Glycobiology 16 (8), pp. 757-765. Fulltext not available.

Guse, C., Koennings, S., Kreye, F., Siepmann, F. , Goepferich, A. and Siepmann, J. (2006) Drug release from lipid-based implants: Elucidation of the underlying mass transport mechanisms. International Journal of Pharmaceutics 314 (2), pp. 137-144. Fulltext not available.

Kelber, O. , Wittwer, A., Lapke, C., Kroll, U., Weiser, D., Okpanyi, S.N. and Heilmann, J. (2006) Ex vivo/in vitro absorption of STW 5 (Iberogast®) and its extract components. Phytomedicine 13, pp. 107-113. Fulltext not available.

Nahrstedt, A, Jürgenliemk, G and Petereit, F (2006) Flavan-3-ols and procyanidins from the bark of Salix purpurea. Planta Medica 72 (11). Fulltext not available.

Breunig, Miriam , Lungwitz, Uta, Liebl, Renate and Goepferich, Achim (2006) Fluorescence resonance energy transfer: Evaluation of the intracellular stability of polyplexes. European Journal of Pharmaceutics and Biopharmaceutics 63 (2), pp. 156-165. Fulltext not available.

Koennings, S., Garcion, E., Faisant, N., Menei, P., Benoit, J.P. and Goepferich, A. (2006) In vitro investigation of lipid implants as a controlled release system for interleukin-18. International Journal of Pharmaceutics 314 (2), pp. 145-152. Fulltext not available.

Lotter, K. (2006) In vivo efficacy of telithromycin on cytokine and nitric oxide formation in lipopolysaccharide-induced acute systemic inflammation in mice. Journal of Antimicrobial Chemotherapy 58 (3), pp. 615-621. Fulltext not available.

Straßer, Andrea and Wittmann, Hans-Joachim (2006) LigPath: a module for predictive calculation of a ligand’s pathway into a receptor-application to the gpH1 - receptor. Journal of Molecular Modeling 13 (1), pp. 209-218. Fulltext not available.

Appel, B., Maschke, A., Weiser, B., Sarhan, H., Englert, C. , Angele, P., Blunk, T. and Göpferich, A. (2006) Lipidic implants for controlled release of bioactive insulin: Effects on cartilage engineered in vitro. International Journal of Pharmaceutics 314 (2), pp. 170-178. Fulltext not available.

Weinrich, Malte, Scheingraber, Stefan, Stremovskaia, Tatiana, Schilling, Martin K., Kees, Frieder and Pistorius, Georg A. (2006) Liver tissue concentrations of levofloxacin after single intravenous administration of 500mg for antibiotic prophylaxis in liver surgery. International Journal of Antimicrobial Agents 28 (3), pp. 221-225. Fulltext not available.

Knerr, Robert, Weiser, Barbara, Drotleff, Sigrid, Steinem, Claudia and Göpferich, Achim (2006) Measuring Cell Adhesion on RGD‐Modified, Self‐Assembled PEG Monolayers Using the Quartz Crystal Microbalance Technique. Macromolecular Bioscience 6 (10), pp. 827-838. Fulltext not available.

Maschke, Angelika, Calí, Nadia, Appel, Bernhard, Kiermaier, Josef, Blunk, Torsten and Göpferich, Achim (2006) Micronization of Insulin by High Pressure Homogenization. Pharmaceutical Research 23 (9), pp. 2220-2229. Fulltext not available.

Heilmann, J, Htay Shwe, H, Aye, M, Sein, MM, Kreitmeier, P and Reiser, O (2006) New Furostanol Glycosides from the Rhizomes of Tacca integrifolia. Planta Medica 72 (11). Fulltext not available.

Spickenreither, Martin, Braun, Stephan, Bernhardt, Günther, Dove, Stefan and Buschauer, Armin (2006) Novel 6-O-acylated vitamin C derivatives as hyaluronidase inhibitors with selectivity for bacterial lyases. Bioorganic & Medicinal Chemistry Letters 16 (20), pp. 5313-5316. Fulltext not available.

Mahboobi, Siavosh, Uecker, Andrea, Sellmer, Andreas, Cénac, Christophe, Höcher, Heymo, Pongratz, Herwig, Eichhorn, Emerich, Hufsky, Harald, Trümpler, Antje, Sicker, Marit, Heidel, Florian, Fischer, Thomas, Stocking, Carol, Elz, Sigurd, Böhmer, Frank-D. and Dove, Stefan (2006) Novel Bis(1H-indol-2-yl)methanones as Potent Inhibitors of FLT3 and Platelet-Derived Growth Factor Receptor Tyrosine Kinase. Journal of Medicinal Chemistry 49 (11), pp. 3101-3115. Fulltext not available.

Karioti, A, Skopeliti, M, Heilmann, J, Tsitsilonis, O and Skaltsa, H (2006) Novel cytotoxic labdane diterpenes from Marrubium cylleneum. Planta Medica 72 (11). Fulltext not available.

Elkharraz, K., Faisant, N., Guse, C., Siepmann, F. , Arica-Yegin, B., Oger, J.M., Gust, R., Goepferich, A. , Benoit, J.P. and Siepmann, J. (2006) Paclitaxel-loaded microparticles and implants for the treatment of brain cancer: Preparation and physicochemical characterization. International Journal of Pharmaceutics 314 (2), pp. 127-136. Fulltext not available.

Gross, Dietmar, Bernhardt, Günther and Buschauer, Armin (2006) Platelet-derived growth factor receptor independent proliferation of human glioblastoma cells: selective tyrosine kinase inhibitors lack antiproliferative activity. Journal of Cancer Research and Clinical Oncology 132 (9), pp. 589-599. Fulltext not available.

Guse, C., Koennings, S., Blunk, T., Siepmann, J. and Goepferich, A. (2006) Programmable implants—From pulsatile to controlled release. International Journal of Pharmaceutics 314 (2), pp. 161-169. Fulltext not available.

Wagenlehner, F.M.E., Lunz, J.C., Kees, F., Wieland, W. and Naber, K.G. (2006) Serum and Prostatic Tissue Concentrations of Moxifloxacin in Patients Undergoing Transurethral Resection of the Prostate. Journal of Chemotherapy 18 (5), pp. 485-489. Fulltext not available.

Pertz, Heinz H., Görnemann, Tilo, Schurad, Björn, Seifert, Roland and Straßer, Andrea (2006) Striking differences of action of lisuride stereoisomers at histamine H1 receptors. Naunyn-Schmiedeberg's Archives of Pharmacology 374 (3), pp. 215-222. Fulltext not available.

Xie, Sheng-Xue, Petrache, Georgiana, Schneider, Erich , Ye, Qi-Zhuang, Bernhardt, Günther, Seifert, Roland and Buschauer, Armin (2006) Synthesis and pharmacological characterization of novel fluorescent histamine H2-receptor ligands derived from aminopotentidine. Bioorganic & Medicinal Chemistry Letters 16 (15), pp. 3886-3890. Fulltext not available.

Neubauer, Markus, Hacker, Michael , Bauer-Kreisel, Petra, Weiser, Barbara, Fischbach, Claudia , Schulz, Michaela B, Goepferich, Achim and Blunk, Torsten (2005) Adipose Tissue Engineering Based on Mesenchymal Stem Cells and Basic Fibroblast Growth Factorin Vitro. Tissue Engineering 11 (11-12), pp. 1840-1851. Fulltext not available.

Pinto, Cibele S., Jinnah, Hyder A., Shirley, Thomas L., Nyhan, William L. and Seifert, Roland (2005) Altered membrane NTPase activity in Lesch–Nyhan disease fibroblasts: comparison with HPRT knockout mice and HPRT‐deficient cell lines. Journal of Neurochemistry 93 (6), pp. 1579-1586. Fulltext not available.

Paper, Dietrich H., Karall, Elisabeth, Kremser, Michaela and Krenn, Liselotte (2005) Comparison of the antiinflammatory effects ofDrosera rotundifolia andDrosera madagascariensis in the HET-CAM assay. Phytotherapy Research 19 (4), pp. 323-326. Fulltext not available.

Gille, Andreas , Guo, Jianxin, Mou, Tung-Chung, Doughty, Michael B., Lushington, Gerald H. and Seifert, Roland (2005) Differential interactions of G-proteins and adenylyl cyclase with nucleoside 5′-triphosphates, nucleoside 5′-[γ-thio]triphosphates and nucleoside 5′-[β,γ-imido]triphosphates. Biochemical Pharmacology 71 (1-2), pp. 89-97. Fulltext not available.

Höcherl, Klaus , Hensel, Corina, Ulbricht, Bettina and Krämer, Bernhard K (2005) Everolimus treatment downregulates renocortical cyclooxygenase‐2 expression in the rat kidney. British Journal of Pharmacology 145 (8), pp. 1112-1122. Fulltext not available.

Fryčák, Petr, Zdráhal, Zbyněk, Ulrichová, Jitka , Wiegrebe, Wolfgang and Lemr, Karel (2005) Evidence of covalent interaction of fumaric acid esters with sulfhydryl groups in peptides. Journal of Mass Spectrometry 40 (10), pp. 1309-1318. Fulltext not available.

Breunig, Miriam , Lungwitz, Uta, Liebl, Renate, Fontanari, Claudia, Klar, Juergen, Kurtz, Armin, Blunk, Torsten and Goepferich, Achim (2005) Gene delivery with low molecular weight linear polyethylenimines. The Journal of Gene Medicine 7 (10), pp. 1287-1298. Fulltext not available.

Ito, Natsuho, Ito, Taisuke, Kromminga, Arno, Bettermann, Albrecht, Takigawa, Masahiro, Kees, Frieder, Straub, Rainer H. and Paus, Ralf (2005) Human hair follicles display a functional equivalent of the hypothalamic‐pituitary‐adrenal (HPA) axis and synthesize cortisol. The FASEB Journal 19 (10), pp. 1332-1334. Fulltext not available.

Menz, Barbara, Knerr, Robert, Göpferich, Achim and Steinem, Claudia (2005) Impedance and QCM analysis of the protein resistance of self-assembled PEGylated alkanethiol layers on gold. Biomaterials 26 (20), pp. 4237-4243. Fulltext not available.

Karioti, Anastasia , Heilmann, Jörg and Skaltsa, Helen (2005) Labdane diterpenes from Marrubium velutinum and Marrubium cylleneum. Phytochemistry 66 (9), pp. 1060-1066. Fulltext not available.

Lieb, E., Hacker, M. , Tessmar, J. , Kunz-Schughart, L.A., Fiedler, J., Dahmen, C., Hersel, U., Kessler, H., Schulz, M.B. and Göpferich, A. (2005) Mediating specific cell adhesion to low-adhesive diblock copolymers by instant modification with cyclic RGD peptides. Biomaterials 26 (15), pp. 2333-2341. Fulltext not available.

Kuehnel, T. S., Schurr, C., Lotter, K. and Kees, F. (2005) Penetration of telithromycin into the nasal mucosa and ethmoid bone of patients undergoing rhinosurgery for chronic sinusitis. Journal of Antimicrobial Chemotherapy 55 (4), pp. 591-594. Fulltext not available.

Ibrahim, Mohamed Abbas, Ismail, Ahmed, Fetouh, Mohamed Ihab and Göpferich, Achim (2005) Stability of insulin during the erosion of poly(lactic acid) and poly(lactic-co-glycolic acid) microspheres. Journal of Controlled Release 106 (3), pp. 241-252. Fulltext not available.

Salmen, Sunnhild, Hoechstetter, Julia, Käsbauer, Christian, Paper, Dieter H., Bernhardt, Günther and Buschauer, Armin (2005) Sulphated Oligosaccharides as Inhibitors of Hyaluronidases from Bovine Testis, Bee Venom and Streptococcus agalactiae. Planta Med. 71, pp. 727-732. Fulltext not available.

Romagnoli, Romeo, Baraldi, Pier Giovanni, Iaconinoto, Maria Antonietta, Carrion, Maria Dora , Tabrizi, Mojgan Aghazadeh, Gambari, Roberto , Borgatti, Monica and Heilmann, Jörg (2005) Synthesis and biological activity of alpha-bromoacryloyl lexitropsin conjugates. European Journal of Medicinal Chemistry 40 (11), pp. 1123-1128. Fulltext not available.

Mahboobi, Siavosh, Sellmer, Andreas, Eichhorn, Emerich, Beckers, Thomas, Fiebig, Heinz-Herbert and Kelter, Gerhard (2005) Synthesis and cytotoxic activity of 2-acyl-1H-indole-4,7-diones on human cancer cell lines. European Journal of Medicinal Chemistry 40 (1), pp. 85-92. Fulltext not available.

Thomas, Katrin, Koelwel, Christoph, Machei, Uwe, Färber, Lothar and Göpferich, Achim (2005) Three Generations of Cyclosporine A Formulations: An In Vitro Comparison. Drug Development and Industrial Pharmacy 31 (4-5), pp. 357-366. Fulltext not available.

Kaftan, H., Hosemann, W., Junghans, D., Göpferich, A., Schindler, E. and Beule, A. (2005) Traumatische Trommelfellperforationen. HNO 53 (6), pp. 539-544. Fulltext not available.

Gust, Ronald, Niebler, Karlheinz and Schönenberger, Helmut (2005) [N-Ethyl- and [N,N‘-Diethyl-1,2-bis(2,6-difluoro-3-hydroxyphenyl)- ethylenediamine]dichloroplatinum(II): Structure and Cytotoxic/Estrogenic Activity in Breast Cancer Cells. Journal of Medicinal Chemistry 48 (23), pp. 7132-7144. Fulltext not available.

Kießling, Stephan, Müller-Newen, Gerhard, Leeb, Sandra N., Hausmann, Martin, Rath, Heiko C., Strater, Jörn, Spottl, Tanja, Schlottmann, Klaus, Grossmann, Johannes, Montero-Julian, F. A., Schölmerich, Jürgen, Andus, Tilo, Buschauer, Armin, Heinrich, Peter C. and Rogler, Gerhard (2004) Functional Expression of the Interleukin-11 Receptor α-Chain and Evidence of Antiapoptotic Effects in Human Colonic Epithelial Cells. The Journal of Biological Chemistry 279 (11), pp. 10304-10315. Fulltext not available.

Walter, Georg, Liebl, Renate and Angerer, Erwin von (2004) 2-phenylindole sulfamates: inhibitors of steroid sulfatase with antiproliferative activity in MCF-7 breast cancer cells. The Journal of Steroid Biochemistry and Molecular Biology 88 (4-5), pp. 409-420. Fulltext not available.

Tingart, Markus J., Apreleva, Maria, Lehtinen, Janne, Zurakowski, David and Warner, Jon J. P. (2004) Anchor Design and Bone Mineral Density Affect the Pull-Out Strength of Suture Anchors in Rotator Cuff Repair. The American Journal of Sports Medicine 32 (6), pp. 1466-1473. Fulltext not available.

Neubauer, Markus, Fischbach, Claudia , Bauer-Kreisel, Petra, Lieb, Esther, Hacker, Michael , Tessmar, Joerg , Schulz, Michaela B., Goepferich, Achim and Blunk, Torsten (2004) Basic fibroblast growth factor enhances PPARγ ligand‐induced adipogenesis of mesenchymal stem cells. FEBS Letters 577 (1-2), pp. 277-283. Fulltext not available.

Ménard, Rozenn, Alban, Susanne, de Ruffray, Patrice, Jamois, Frank, Franz, Gerhard, Fritig, Bernard, Yvin, Jean-Claude and Kauffmann, Serge (2004) Beta-1,3 glucan sulfate, but not beta-1,3 glucan, induces the salicylic acid signaling pathway in tobacco and Arabidopsis. The Plant Cell 16 (11), pp. 3020-3032. Fulltext not available.

Drotleff, S, Lungwitz, U, Breunig, M , Dennis, A, Blunk, T, Tessmar, J and Göpferich, A (2004) Biomimetic polymers in pharmaceutical and biomedical sciences. European Journal of Pharmaceutics and Biopharmaceutics 58 (2), pp. 385-407. Fulltext not available.

Bernhardt, Günther, Brunner, Henri, Gruber, Nick, Lottner, Christian, Pushpan, Simi K., Tsuno, Takashi and Zabel, Manfred (2004) Carboplatin derivatives with superior antitumor activity compared to the parent compound. Inorganica Chimica Acta 357 (15), pp. 4452-4466. Fulltext not available.

Dittmar, Michael, Kiourkenidis, Georgios, Horn, Markus, Bollwein, Susanne and Bernhardt, Günther (2004) Cerebral Ischemia, Matrix Metalloproteinases, and TNF-α: MMP Inhibitors May Act Not Exclusively by Reducing MMP Activity. Stroke 35 (7). Fulltext not available.

Kees, F., Mair, G., Dittmar, M. and Bucher, M. (2004) Cicloral versus neoral: A bioequivalence study in healthy volunteers on the influence of a fat-rich meal on the bioavailability of cicloral. Transplantation Proceedings 36 (10), pp. 3234-3238. Fulltext not available.

Lottner, Christian, Knuechel, Ruth, Bernhardt, Guenther and Brunner, Henri (2004) Combined chemotherapeutic and photodynamic treatment on human bladder cells by hematoporphyrin–platinum(II) conjugates. Cancer Letters 203 (2), pp. 171-180. Fulltext not available.

Gürtler, Ulrich, Fuchs, Peter, Stangelmayer, Achim, Bernhardt, Günther, Buschauer, Armin and Spruss, Thilo (2004) Construction and validation of a microprocessor controlled extracorporal circuit in rats for the optimization of isolated limb perfusion. Archiv der Pharmazie 33 (12), pp. 672-681. Fulltext not available.

Höcherl, Klaus, Kees, Frieder, Krämer, Bernhard K. and Kurtz, Armin (2004) Cyclosporine A attenuates the natriuretic action of loop diuretics by inhibition of renal COX-2 expression. Kidney International 65 (6), pp. 2071-2080. Fulltext not available.

Lottner, Christian, Knuechel, Ruth, Bernhardt, Günther and Brunner, Henri (2004) Distribution and subcellular localization of a water-soluble hematoporphyrin-platinum(II) complex in human bladder cancer cells. Cancer letters 215 (2), pp. 167-177. Fulltext not available.

Lieb, E., Milz, S. , Vogel, T., Hacker, M. , Dauner, M. and Schulz, M.B. (2004) Effects of Transforming Growth Factor β1 on Bonelike Tissue Formation in Three-Dimensional Cell Culture. I. Culture Conditions and Tissue Formation. Tissue Engineering 10 (9-10), pp. 1399-1413. Fulltext not available.

Lieb, E., Vogel, T., Milz, S. , Dauner, M. and Schulz, M.B. (2004) Effects of Transforming Growth Factor β1 on Bonelike Tissue Formation in Three-Dimensional Cell Culture. II: Osteoblastic Differentiation. Tissue Engineering 10 (9-10), pp. 1414-1425. Fulltext not available.

Demirci, Betül , Paper, Dietrich H., Demirci, Fatih , Başer, K. Hüsnü Can and Franz, Gerhard (2004) Essential Oil of Betula pendula Roth. Buds. Evidence-based complementary and alternative medicine : eCAM 1 (3), pp. 301-303. Fulltext not available.

Fischbach, Claudia , Spruß, Thilo, Weiser, Barbara, Neubauer, Markus, Becker, Christian, Hacker, Michael , Göpferich, Achim and Blunk, Torsten (2004) Generation of mature fat pads in vitro and in vivo utilizing 3-D long-term culture of 3T3-L1 preadipocytes. Experimental Cell Research 300 (1), pp. 54-64. Fulltext not available.

Jirovsky, David and Wiegrebe, Wolfgang (2004) HPLC-Analysis of Fumarates in Biological Matrices. Monatshefte f�r Chemie/Chemical Monthly 135 (12), pp. 1563-1568. Fulltext not available.

Färber, L, Haus, U, Späth, M and Drechsler, S (2004) Physiology and pathophysiology of the 5‐HT3receptor. Scandinavian Journal of Rheumatology 33 (sup119), pp. 2-8. Fulltext not available.

Dove, Stefan (2004) Picolinic Acids as Inhibitors of Dopamine β‐Monooxygenase: QSAR and Putative Binding Site. Archiv der Pharmazie 337 (12), pp. 645-653. Fulltext not available.

Breunig, Miriam , Lungwitz, Uta, Klar, Juergen, Kurtz, Armin, Blunk, Torsten and Goepferich, Achim (2004) Polyplexes of Polyethylenimine and per-N-methylated Polyethylenimine-Cytotoxicity and Transfection Efficiency. Journal of Nanoscience and Nanotechnology 4 (5), pp. 512-520. Fulltext not available.

Straub, R H , make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference , make_name_string expected hash reference and make_name_string expected hash reference (2004) Renal clearance and daily excretion of cortisol and adrenal androgens in patients with rheumatoid arthritis and systemic lupus erythematosus. Annals of the Rheumatic Diseases 63 (8), pp. 961-968. Fulltext not available.

Goppel, Martin and Franz, Gerhard (2004) Stability Control of Senna Leaves and Senna extracts. Planta Medica 70, pp. 432-436. Fulltext not available.

Walter, Georg, Liebl, Renate and Angerer, Erwin von (2004) Stilbene-based inhibitors of estrone sulfatase with a dual mode of action in human breast cancer cells. Archiv der Pharmazie 337 (12), pp. 634-644. Fulltext not available.

Pertz, Heinz, Elz, Sigurd and Schunack, Walter (2004) Structure-Activity Relationships of Histamine H1-Receptor Agonists. Mini-Reviews in Medicinal Chemistry 4 (9), pp. 935-940. Fulltext not available.

Dove, Stefan, Elz, Sigurd, Seifert, Roland and Buschauer, Armin (2004) Structure-Activity Relationships of Histamine H2 Receptor Ligands+. Mini-Reviews in Medicinal Chemistry 4 (9), pp. 941-954. Fulltext not available.

Mahboobi, Siavosh, Sellmer, Andreas, Burgemeister, Thomas, Lyssenko, Alexei and Schollmeyer, Dieter (2004) Synthesis of Naturally Occurring Pyrazine and Imidazole Alkaloids from Botryllus LeachiRID=?a?ID=?a? Dedicated to Prof. G . Märkl on the occasion of his 75 th birthday. Monatshefte f�r Chemie / Chemical Monthly 135 (3), pp. 333-342. Fulltext not available.

Welsh, Michael, Welsh, Charlotte, Ekman, Maria, Dixelius, Johan, Hägerkvist, Robert, Anneren, Cecilia, Åkerblom, Björn, Mahboobi, Siavosh, Chandrasekharan, Subhashini and Liu, Edison T. (2004) The tyrosine kinase FRK/RAK participates in cytokine-induced islet cell cytotoxicity. Biochemical Journal 382 (1), pp. 261-268. Fulltext not available.

Sadek, B., Elz, S., Pertz, H.H., Stark, H. and Schunack, W. (2004) Unexpected partial H1-receptor agonism of imidazole-type histamine H3-receptor antagonists lacking a basic side chain. Inflammation Research 53 (S2). Fulltext not available.

Fuchs-Koelwel, B., Koelwel, C., G�pferich, A., Gabler, B., Wiegrebe, E. and Lohmann, C. P. (2004) Vertr�glichkeit eines neuen Kalzium-Alginat-Insertes zur kontrollierten medikament�sen Therapie am Auge. Der Ophthalmologe 101 (5), pp. 496-499. Fulltext not available.

Schertl, Sabine, Hartmann, Rolf W., Batzl-Hartmann, Christine, Bernhardt, Günther, Spruß, Thilo, Beckenlehner, Karin, Koch, Marion, Krauser, Rudolf, Schlemmer, Richard, Gust, Ronald and Schönenberger, Helmut (2004) [1, 2-Bis(2, 6-difluoro-3-hydroxyphenyl)ethylene-diamine]platinum(II) complexes, compounds for the endocrine therapy of breast cancer - mode of action I: antitumor activity due to the reduction of the endogenous estrogen level. Archiv der Pharmazie 337 (6), pp. 335-348. Fulltext not available.

Schertl, Sabine, Hartmann, Rolf W., Batzl-Hartmann, Christine, Bernhardt, Günther, Spruss, Thilo, Beckenlehner, Karin, Koch, Marion, Krauser, Rudolf, Schlemmer, Richard, Gust, Ronald and Schönenberger, Helmut (2004) [1, 2-Bis(2, 6-difluoro-3-hydroxyphenyl)ethylene-diamine]platinum(II) complexes, compounds for the endocrine therapy of breast cancer - mode of action II: contribution of drug inactivation, cellular drug uptake and sterical factors in the drug-target interaction to the antitumor activity. Archiv der Pharmazie 337 (6), pp. 349-359. Fulltext not available.

Botzki, Alexander , Rigden, Daniel J. , Braun, Stephan, Nukui, Masatoshi, Salmen, Sunnhild, Hoechstetter, Julia, Bernhardt, Günther, Dove, Stefan, Jedrzejas, Mark J. and Buschauer, Armin (2004) l-Ascorbic Acid 6-Hexadecanoate, a Potent Hyaluronidase Inhibitor. Journal of Biological Chemistry 279 (44), pp. 45990-45997. Fulltext not available.

Li, Liantao, Mayer, Matthias, Schneider, Erich , Schreiber, Elvira, Bernhardt, Günther, Peng, Shiqi and Buschauer, Armin (2003) Preparation of fluorescent nonpeptidic neuropeptide Y receptor ligands: analogues of the quinazoline-type anti-obesity Y5 antagonist CGP 71683A. Arch Pharm (Weinheim) 336 (12), pp. 585-590. Fulltext not available.

Beckers, T., and Mahboobi, S., (2003) Natural, semisynthetic and synthetic microtubule inhibitors for cancer therapy. Drugs of the Future 28 (8), 0767. Fulltext not available.

Böhmer, Frank D., Karagyozov, Luchezar, Uecker, Andrea, Serve, Hubert, Botzki, Alexander , Mahboobi, Siavosh and Dove, Stefan (2003) A Single Amino Acid Exchange Inverts Susceptibility of Related Receptor Tyrosine Kinases for the ATP Site Inhibitor STI-571. Journal of Biological Chemistry 278 (7), pp. 5148-5155. Fulltext not available.

Lucke, A (2003) Acylation of peptides by lactic acid solutions. European Journal of Pharmaceutics and Biopharmaceutics 55 (1), pp. 27-33. Fulltext not available.

Oettl, Martin, Hoechstetter, Julia, Asen, Iris, Bernhardt, Günther and Buschauer, Armin (2003) Comparative characterization of bovine testicular hyaluronidase and a hyaluronate lyase from Streptococcus agalactiae in pharmaceutical preparations. European Journal of Pharmaceutical Sciences 18 (3-4), pp. 267-277. Fulltext not available.

Kaiser, Alexander, Mayer, Klaus K., Sellmer, Andreas and Wiegrebe, Wolfgang (2003) Electron Impact Induced Fragmentation of Aromatic Alkoxyimines II [5]. Formation and Transformation of Heterocyclic Radical Cations in the Gas Phase a. Monatshefte f�r Chemie / Chemical Monthly 134 (3), pp. 343-354. Fulltext not available.

Dittmar, Michael, Spruss, Thilo, Schuierer, Gerhard and Horn, Markus (2003) External Carotid Artery Territory Ischemia Impairs Outcome in the Endovascular Filament Model of Middle Cerebral Artery Occlusion in Rats. Stroke 34 (9), pp. 2252-2257. Fulltext not available.

Castrop, Hayo, Klar, Jürgen, Wagner, Charlotte, Höcherl, Klaus and Kurtz, Armin (2003) General inhibition of renocortical cyclooxygenase-2 expression by the renin-angiotensin system. American Journal of Physiology-Renal Physiology 284 (3), F518-F524. Fulltext not available.

Hosemann, Werner, Schindler, Edith, Wiegrebe, Eckard and Göpferich, Achim (2003) Innovative frontal sinus stent acting as a local drug-releasing system. European Archives of Oto-Rhino-Laryngology 260 (3), pp. 131-134. Fulltext not available.

Iwasa, Kinuko, Kuribayashi, Ayako, Sugiura, Makiko, Moriyasu, Masataka, Lee, Dong-Ung and Wiegrebe, Wolfgang (2003) LC–NMR and LC–MS analysis of 2,3,10,11-oxygenated protoberberine metabolites in Corydalis cell cultures. Phytochemistry 64 (7), pp. 1229-1238. Fulltext not available.

Vogelhuber, W., Magni, E., Mouro, M., Spruß, T., Guse, C., Gazzaniga, A. and Göpferich, A. (2003) Monolithic Triglyceride Matrices: A Controlled-Release System for Proteins. Pharmaceutical Development and Technology 8 (1), pp. 71-79. Fulltext not available.

Vogelhuber, W, make_name_string expected hash reference, make_name_string expected hash reference and make_name_string expected hash reference (2003) Monolithic glyceryl trimyristate matrices for parenteral drug release applications. European Journal of Pharmaceutics and Biopharmaceutics 55 (1), pp. 133-138. Fulltext not available.

Menghin, Sonja, Pertz, Heinz H., Kramer, Kai, Seifert, Roland, Schunack, Walter and Elz, Sigurd (2003) Nα-Imidazolylalkyl and Pyridylalkyl Derivatives of Histaprodifen: Synthesis and in Vitro Evaluation of Highly Potent Histamine H1-Receptor Agonists. Journal of Medicinal Chemistry 46 (25), pp. 5458-5470. Fulltext not available.

Lieb, E., Tessmar, J. , Hacker, M. , Fischbach, C. , Rose, D., Blunk, T., Mikos, A.G., Göpferich, A. and Schulz, M.B. (2003) Poly(D,L-lactic acid)-Poly(ethylene glycol)-Monomethyl Ether Diblock Copolymers Control Adhesion and Osteoblastic Differentiation of Marrow Stromal Cells. Tissue Engineering 9 (1), pp. 71-84. Fulltext not available.

Loew, D. and Franz, G. (2003) Quality aspects of traditional and industrial Kava-extracts. Phytomedicine 10 (6-7), pp. 610-612. Fulltext not available.

Krenn, Liselotte , Presser, Armin, Pradhan, Riddhi, Bahr, Beate, Paper, Dietrich H., Mayer, Klaus K. and Kopp, Brigitte (2003) Sulfemodin 8-O-β-d-Glucoside, a New Sulfated Anthraquinone Glycoside, and Antioxidant Phenolic Compounds from Rheum emodi. Journal of Natural Products 66 (8), pp. 1107-1109. Fulltext not available.

Govoni, Marinella, Bakker, Remko A., van de Wetering, Ineke, Smit, Martine J., Menge, Wiro M. B. P., Timmerman, Henk, Elz, Sigurd, Schunack, Walter and Leurs, Rob (2003) Synthesis and Pharmacological Identification of Neutral Histamine H1-Receptor Antagonists. Journal of Medicinal Chemistry 46 (26), pp. 5812-5824. Fulltext not available.

Li, Liantao, Kracht, Julia, Peng, Shiqi, Bernhardt, Günther and Buschauer, Armin (2003) Synthesis and pharmacological activity of fluorescent histamine H1 receptor antagonists related to mepyramine,. Bioorganic & Medicinal Chemistry Letters 13 (7), pp. 1245-1248. Fulltext not available.

Radons, Jürgen, Dove, Stefan, Neumann, Detlef , Altmann, Reinhold, Botzki, Alexander , Martin, Michael U. and Falk, Werner (2003) The Interleukin 1 (IL-1) Receptor Accessory Protein Toll/IL-1 Receptor Domain. Journal of Biological Chemistry 278 (49), pp. 49145-49153. Fulltext not available.

Tessmar, Jörg , Mikos, Antonios and Göpferich, Achim (2003) The use of poly(ethylene glycol)-block-poly(lactic acid) derived copolymers for the rapid creation of biomimetic surfaces. Biomaterials 24 (24), pp. 4475-4486. Fulltext not available.

Hacker, Michael , Tessmar, Jörg , Neubauer, Markus, Blaimer, Andrea, Blunk, Torsten, Göpferich, Achim and Schulz, Michaela B (2003) Towards biomimetic scaffolds: Anhydrous scaffold fabrication from biodegradable amine-reactive diblock copolymers. Biomaterials 24 (24), pp. 4459-4473. Fulltext not available.

Kees, Martin G., Pongratz, Georg , Kees, Frieder, Schölmerich, Jürgen and Straub, Rainer H. (2003) Via β-adrenoceptors, stimulation of extrasplenic sympathetic nerve fibers inhibits lipopolysaccharide-induced TNF secretion in perfused rat spleen. Journal of Neuroimmunology 145 (1-2), pp. 77-85. Fulltext not available.

Lucke, Andrea, Kiermaier, Josef and Göpferich, Achim (2002) UNSPECIFIED Pharmaceutical Research 19 (2), pp. 175-181. Fulltext not available.

Parker, S. L., Parker, M. S., Lundell, I., Balasubramaniam, A., Buschauer, Armin, Kane, J. K., Yalcin, A. and Berglund, M. M. (2002) Agonist internalization by cloned Y1 neuropeptide Y (NPY) receptor in Chinese hamster ovary cells shows strong preference for NPY, endosome-linked entry and fast receptor recycling. Regulatory Peptides 107 (1-3), pp. 49-62. Fulltext not available.

Apers, Sandra, Paper, Dietrich, Bürgermeister, Jutta, Baronikova, Slavka, Van Dyck, Stefaan, Lemière, Guy, Vlietinck, Arnold and Pieters, Luc (2002) Antiangiogenic Activity of Synthetic Dihydrobenzofuran Lignans. Journal of Natural Products 65 (5), pp. 718-720. Fulltext not available.

Alban, S., Schauerte, A. and Franz, Gerhard (2002) Anticoagulant sulfated polysaccharides: Part I. Synthesis and structure–activity relationships of new pullulan sulfates. Carbohydrate Polymers 47, pp. 267-276. Fulltext not available.

Teller, S, Krämer, D, Böhmer, S-A, Tse, KF, Small, D, Mahboobi, S, Wallrapp, C, Beckers, T, Kratz-Albers, K, Schwäble, J, Serve, H and Böhmer, F-D (2002) Bis(1H-2-indolyl)-1-methanones as inhibitors of the hematopoietic tyrosine kinase Flt3. Leukemia 16 (8), pp. 1528-1534. Fulltext not available.

Mahboobi, Siavosh, Teller, Steffen, Pongratz, Herwig, Hufsky, Harald, Sellmer, Andreas, Botzki, Alexander , Uecker, Andrea, Beckers, Thomas, Baasner, Silke, Schächtele, Christoph, Überall, Florian, Kassack, Matthias U., Dove, Stefan and Böhmer, Frank-D. (2002) Bis(1H-2-indolyl)methanones as a Novel Class of Inhibitors of the Platelet-Derived Growth Factor Receptor Kinase. Journal of Medicinal Chemistry 45 (5), pp. 1002-1018. Fulltext not available.

Gooch, K.J., Blunk, T., Courter, D.L., Sieminski, A.L., Vunjak-Novakovic, G. and Freed, L.E. (2002) Bone Morphogenetic Proteins-2, -12, and -13 Modulatein VitroDevelopment of Engineered Cartilage. Tissue Engineering 8 (4), pp. 591-601. Fulltext not available.

Koehler, Jens, Kuehnel, Thomas, Kees, Frieder, Hoecherl, Klaus and Grobecker, Horst F. (2002) Comparison of Bioavailability and Metabolism with Two Commercial Formulations of Cyclosporine A in Rats. Drug Metabolism and Disposition 30 (6), pp. 658-662. Fulltext not available.

Höcherl, Klaus , Dreher, Franziska, Kurtz, Armin and Bucher, Michael (2002) Cyclooxygenase-2 Inhibition Attenuates Lipopolysaccharide-Induced Cardiovascular Failure. Hypertension 40 (6), pp. 947-953. Fulltext not available.

Ho[Combining Diaeresis]cherl, Klaus , Dreher, Franziska, Vitzthum, Helga, Ko[Combining Diaeresis]hler, Jens and Kurtz, Armin (2002) Cyclosporine A Suppresses Cyclooxygenase-2 Expression in the Rat Kidney. Journal of the American Society of Nephrology 13 (10), pp. 2427-2436. Fulltext not available.

Höcherl, Klaus, Endemann, Dierk, Kammerl, Martin C, Grobecker, Horst F and Kurtz, Armin (2002) Cyclo‐oxygenase‐2 inhibition increases blood pressure in rats. British Journal of Pharmacology 136 (8), pp. 1117-1126. Fulltext not available.

Kellner, Karin, Liebsch, Gregor, Klimant, Ingo, Wolfbeis, Otto S. , Blunk, Torsten, Schulz, Michaela B. and Göpferich, Achim (2002) Determination of oxygen gradients in engineered tissue using a fluorescent sensor. Biotechnology and Bioengineering 80 (1), pp. 73-83. Fulltext restricted.

Blunk, Torsten, Sieminski, Alisha L., Gooch, Keith J., Courter, Donald L., Hollander, Anthony P., Nahir, A. Menahem, Langer, Robert, Vunjak-Novakovic, Gordana and Freed, Lisa E. (2002) Differential Effects of Growth Factors on Tissue-Engineered Cartilage. Tissue Engineering 8 (1), pp. 73-84. Fulltext not available.

Alban, S., Classen, B., Brunner, G., Franz, Gerhard and Blaschek, W. (2002) Differentiation between the Complement Modulating Effects of an Arabinogalactan-Protein from Echinacea purpurea and Heparin. (Dedicated to the 65th birthday of Prof. Dr. Gerhard Franz). Planta Medica 68, pp. 1118-1124. Fulltext not available.

El-Subbagh, Hussein, Wittig, Thomas, Decker, Michael, Elz, Sigurd, Nieger, Martin and Lehmann, Jochen (2002) Dopamine/Serotonin Receptor Ligands. Part IV [1]: Synthesis and Pharmacology of Novel 3-Benzazecines and 3-Benzazonines as Potential 5-HT2A and Dopamine Receptor Ligands. Archiv der Pharmazie 335 (9), pp. 443-448. Fulltext not available.

Bucher, M., Mair, G. and Kees, F. (2002) Effect of roxithromycin on the pharmacokinetics of lovastatin in volunteers. European Journal of Clinical Pharmacology 57 (11), pp. 787-791. Fulltext not available.

Machein, U., Buss, B., Spiller, I., Braun, J., Rudwaleit, M., Faerber, L. and Sieper, J. (2002) Effective treatment of early rheumatoid arthritis with a combination of methotrexate, prednisolone and cyclosporin. Rheumatology 41 (1), pp. 110-111. Fulltext not available.

Kellner, Karin, Lang, Kurt, Papadimitriou, Apollon, Leser, Ulrike, Milz, Stefan , Schulz, Michaela B., Blunk, Torsten and Göpferich, Achim (2002) Effects of Hedgehog Proteins on Tissue Engineering of Cartilagein Vitro. Tissue Engineering 8 (4), pp. 561-572. Fulltext not available.

Vogelhuber, Werner, Spruß, Thilo, Bernhardt, Günther, Buschauer, Armin and Göpferich, Achim (2002) Efficacy of BCNU and paclitaxel loaded subcutaneous implants in the interstitial chemotherapy of U-87 MG human glioblastoma xenografts,. International Journal of Pharmaceutics 238 (1-2), pp. 111-121. Fulltext not available.

Bernhardt, Günther, Beckenlehner, Karin, Spruß, Thilo, Schlemmer, Richard, Reile, Herta and Schönenberger, Helmut (2002) Establishment and Characterization of New Murine Breast Cancer Cell Lines. Archiv der Pharmazie 335 (2-3), pp. 55-68. Fulltext not available.

Letzel, Matthias C, Grützmacher, Hans-Friedrich, Fürst, Thomas, Mayer, Klaus K and Wiegrebe, Wolfgang (2002) Functional group migration in benzaldoxime-O-n-propyl ether radical cation. International Journal of Mass Spectrometry 217 (1-3), pp. 153-168. Fulltext not available.

Lottner, Christian, Bart, Karl-Christian, Bernhardt, Günther and Brunner, Henri (2002) Hematoporphyrin-Derived Soluble Porphyrin−Platinum Conjugates with Combined Cytotoxic and Phototoxic Antitumor Activity. Journal of Medicinal Chemistry 45 (10), pp. 2064-2078. Fulltext not available.

Sasse, Astrid , Ligneau, Xavier, Rouleau, Agnès, Elz, Sigurd, Ganellin, C. Robin, Arrang, Jean-Michel, Schwartz, Jean-Charles, Schunack, Walter and Stark, Holger (2002) Influence of Bulky Substituents on Histamine H3Receptor Agonist/Antagonist Properties. Journal of Medicinal Chemistry 45 (18), pp. 4000-4010. Fulltext not available.

Bürgermeister, Jutta, Paper, Dietrich H, Vogl, Horst, Linhardt, Robert J and Franz, Gerhard (2002) LaPSvS1, a (1→3)-β-galactan sulfate and its effect on angiogenesis in vivo and in vitro. Carbohydrate Research 337 (16), pp. 1459-1466. Fulltext not available.

Stratz, Th., Färber, L. and Müller, W. (2002) Local treatment of tendinopathies: a comparison between tropisetron and depot corticosteroids combined with local anesthetics. Scandinavian Journal of Rheumatology 31 (6), pp. 366-370. Fulltext not available.

Alban, Susanne, Welzel, Dieter and Hemker, H. Coenraad (2002) Pharmacokinetic and pharmacodynamic characterization of a medium-molecular-weight heparin in comparison with UFH and LMWH. Seminars in thrombosis and hemostasis 28 (4), pp. 369-378. Fulltext not available.

Weiss, Thomas S. , Bernhardt, Günther, Buschauer, Armin, Thasler, Wolfgang E., Dolgner, Doris, Zirngibl, Hubert and Jauch, Karl-Walter (2002) Polyamine levels of human colorectal adenocarcinomas are correlate with tumor stage and grade,. International Journal of Colorectal Disease 17 (6), pp. 381-387. Fulltext not available.

Göpferich, A and Tessmar, J (2002) Polyanhydride degradation and erosion. Advanced Drug Delivery Reviews 54 (7), pp. 911-931. Fulltext not available.

Graßmann, Sven, Sadek, Bassem, Ligneau, Xavier, Elz, Sigurd, Ganellin, C.Robin, Arrang, Jean-Michel, Schwartz, Jean-Charles, Stark, Holger and Schunack, Walter (2002) Progress in the proxifan class: heterocyclic congeners as novel potent and selective histamine H3-receptor antagonists. European Journal of Pharmaceutical Sciences 15 (4), pp. 367-378. Fulltext not available.

Höcherl, K., Kammerl, M., Kees, F., Krämer, B. K., Grobecker, H. F. and Kurtz, A. (2002) Role of renal nerves in stimulation of renin, COX-2, and nNOS in rat renal cortex during salt deficiency. American Journal of Physiology-Renal Physiology 282 (3), F478-F484. Fulltext not available.

Lottner, Christian, Bart, Karl-Christian, Bernhardt, Günther and Brunner, Henri (2002) Soluble Tetraarylporphyrin−Platinum Conjugates as Cytotoxic and Phototoxic Antitumor Agents. Journal of Medicinal Chemistry 45 (10), pp. 2079-2089. Fulltext not available.

Golob, Thomas, Liebl, Renate and von Angerer, Erwin (2002) Sulfamoyloxy-substituted 2-phenylindoles. Bioorganic & Medicinal Chemistry 10 (12), pp. 3941-3953. Fulltext not available.

Sieminski, A.L., Padera, R.F., Blunk, T. and Gooch, K.J. (2002) Systemic Delivery of Human Growth Hormone Using Genetically Modified Tissue-Engineered Microvascular Networks: Prolonged Delivery and Endothelial Survival with Inclusion of Nonendothelial Cells. Tissue Engineering 8 (6), pp. 1057-1069. Fulltext not available.

Lucke, Andrea, Fustella, Elisabetta, Teßmar, Jörg , Gazzaniga, Andrea and Göpferich, Achim (2002) The effect of poly(ethylene glycol)–poly(d,l-lactic acid) diblock copolymers on peptide acylation. Journal of Controlled Release 80 (1-3), pp. 157-168. Fulltext not available.

Bouchal, Jan , Kolář, Zdeněk , Mad’arová, Jana, Hlobilková, Alice and von Angerer, Erwin (2002) The effects of natural ligands of hormone receptors and their antagonists on telomerase activity in the androgen sensitive prostatic cancer cell line LNCaP. Biochemical Pharmacology 63 (6), pp. 1177-1181. Fulltext not available.

Fellner, Stephan, Bauer, Björn, Miller, David S., Schaffrik, Martina, Fankhänel, Martina, Spruß, Thilo, Bernhardt, Günther, Graeff, Claudia, Färber, Lothar, Gschaidmeier, Harald, Buschauer, Armin and Fricker, Gert (2002) Transport of paclitaxel (Taxol) across the blood-brain barrier in vitro and in vivo. Journal of Clinical Investigation 110 (9), pp. 1309-1318. Fulltext not available.

Burkersroda, Friederike von, Schedl, Luise and Göpferich, Achim (2002) Why degradable polymers undergo surface erosion or bulk erosion. Biomaterials 23 (21), pp. 4221-4231. Fulltext not available.

Schertl, Sabine, Hartmann, Rolf W., Batzl-Hartmann, Christine, Schlemmer, Richard, Spruß, Thilo, Bernhardt, Günther, Gust, Ronald and Schönenberger, Helmut (2001) 1-(2,6-Dichloro-4-hydroxyphenyl)-2-phenylethanes — New Biological Response Modifiers for the Therapy of Breast Cancer. Synthesis and Evaluation of Estrogenic/Antiestrogenic Properties. Archiv der Pharmazie 334 (4), pp. 125-137. Fulltext not available.

Müller, Klaus, Breu, Klaus and Reindl, Hans (2001) 10-Phenylbutyryl-substituted anthracenones as inhibitors of keratinocyte growth and LTB4 biosynthesis. European Journal of Medicinal Chemistry 36 (2), pp. 179-184. Fulltext not available.

Mann, Bianca, Hartner, Andrea, Jensen, Boye L., Hilgers, Karl F., Höcherl, Klaus, Krämer, Bernhard K. and Kurtz, Armin (2001) Acute upregulation of COX-2 by renal artery stenosis. American Journal of Physiology-Renal Physiology 280 (1), F119-F125. Fulltext not available.

Müller, Klaus, Reindl, Hans and Breu, Klaus (2001) Antipsoriatic Anthrones with Modulated Redox Properties. 5. Potent Inhibition of Human Keratinocyte Growth, Induction of Keratinocyte Differentiation, and Reduced Membrane Damage by Novel 10-Arylacetyl-1,8-dihydroxy-9(10H)-anthracenones. Journal of Medicinal Chemistry 44 (5), pp. 814-821. Fulltext not available.

Otto, Angela, Schubert, Sybilla and Netzker, Roland (2001) Changes in the expression and binding properties of the estrogen receptor in MCF-7 breast cancer cells during growth inhibition by tamoxifen and cisplatin. Cancer Chemotherapy and Pharmacology 48 (4), pp. 305-311. Fulltext not available.

Schuster, Andreas, Götte, Carsten, Bernhardt, Günther and Buschauer, Armin (2001) Chiral separation of pheniramine-like 3-phenyl-3-heteroarylpropylamines by CE and HPLC methods,. Chirality 13 (6), pp. 285-293. Fulltext not available.

Elisseeff, Jennifer , McIntosh, Winnette, Fu, Karen, Blunk, Torsten and Langer, Robert (2001) Controlled‐release of IGF‐I and TGF‐β1 in a photopolymerizing hydrogel for cartilage tissue engineering. Journal of Orthopaedic Research 19 (6), pp. 1098-1104. Fulltext not available.

Müller, Klaus and Reindl, Hans (2001) Cornified Envelope Formation by Anthralin, Simple Analogues, and Related Anthracenones. Archiv der Pharmazie 334 (3), pp. 86-92. Fulltext not available.

Kees, F, Bucher, M, Mair, G and Grobecker, H (2001) Determination of opipramol in human plasma by high-performance liquid chromatography with photometric detection using a cyanopropyl column. Journal of Chromatography B: Biomedical Sciences and Applications 753 (2), pp. 337-342. Fulltext not available.

Reithmeier, Helmut, Herrmann, Joachim and Göpferich, Achim (2001) Development and characterization of lipid microparticles as a drug carrier for somatostatin. International Journal of Pharmaceutics 218 (1-2), pp. 133-143. Fulltext not available.

Wolf, Konrad, Kurtz, Armin, Pfeifer, Michael, Höcherl, Klaus, Riegger, Günter and Krämer, Bernhard (2001) Different regulation of left ventricular ANP, BNP and adrenomedullin mRNA in the two-kidney, one-clip model of renovascular hypertension. Pfl�gers Archiv European Journal of Physiology 442 (2), pp. 212-217. Fulltext not available.

de Martin, Rainer, Mrowietz, Ulrich, Wiegrebe, Wolfgang, Jirovsky, David, Loewe, Robert, Pillinger, Manuela , Gröger, Marion, Holnthoner, Wolfgang, Wolff, Klaus and Petzelbauer, Peter (2001) Dimethylfumarate Inhibits Tumor-Necrosis-Factor-Induced CD62E Expression in an NF-κB-Dependent Manner. Journal of Investigative Dermatology 117 (6), pp. 1363-1368. Fulltext not available.

Schlemmer, Richard, Spruß, Thilo, Bernhardt, Günther and Schönenberger, Helmut (2001) Does [meso-1,2-bis(2,6-dichloro-4-hydroxy-phenyl) ethylenediamine]dichloroplatinum(II) act as an immune response modifier? IV. Inhibition of the proliferation-increasing effect of progressively growing MXT-M-3,2 breast cancer on phagocytes by the title compound. Archiv der Pharmazie 334 (10), pp. 309-317. Fulltext not available.

Gooch, K. J., Kwon, J. H., Blunk, T., Langer, R., Freed, L. E. and Vunjak-Novakovic, G. (2001) Effects of mixing intensity on tissue-engineered cartilage. Biotechnology and Bioengineering 72 (4), pp. 402-407. Fulltext not available.

Müller, Klaus, Reindl, Hans and Breu, Klaus (2001) Heterocyclic substituted anthralin derivatives as inhibitors of keratinocyte growth and inducers of differentiation. Bioorganic & Medicinal Chemistry Letters 11 (1), pp. 47-50. Fulltext not available.

Gooch, K.J., Blunk, T., Courter, D.L., Sieminski, A.L., Bursac, P.M., Vunjak-Novakovic, G. and Freed, L.E. (2001) IGF-I and Mechanical Environment Interact to Modulate Engineered Cartilage Development. Biochemical and Biophysical Research Communications 286 (5), pp. 909-915. Fulltext not available.

Iwasa, Kinuko, Moriyasu, Masataka, Yamori, Takao, Turuo, Takashi, Lee, Dong-Ung and Wiegrebe, Wolfgang (2001) In Vitro Cytotoxicity of the Protoberberine-Type Alkaloids. Journal of Natural Products 64 (7), pp. 896-898. Fulltext not available.

Bischoff, Andrea, Püttmann, Kristina, Kötting, Annette, Moser, Christiane, Buschauer, Armin and Michel, Martin C. (2001) Limited signal transduction repertoire of human Y_5 neuropeptide Y receptors expressed in HEC-B cells. Peptides 22 (3), pp. 387-394. Fulltext not available.

Reithmeier, Helmut, Herrmann, Joachim and Göpferich, Achim (2001) Lipid microparticles as a parenteral controlled release device for peptides. Journal of Controlled Release 73 (2-3), pp. 339-350. Fulltext not available.

Kammerl, M (2001) Low sodium and furosemide–induced stimulation of the renin system in man is mediated by cyclooxygenase 2. Clinical Pharmacology & Therapeutics 70 (5), pp. 468-474. Fulltext not available.

Siepmann, J and make_name_string expected hash reference (2001) Mathematical modeling of bioerodible, polymeric drug delivery systems. Advanced Drug Delivery Reviews 48 (2-3), pp. 229-247. Fulltext not available.

Alban, Susanne (2001) Molecular Weight-Dependent Influence of Heparin on the Form of Tissue Factor Pathway Inhibitor Circulating in Plasma. Seminars in Thrombosis and Hemostasis 27 (05), pp. 503-512. Fulltext not available.

Jirovsky, David, Sellmer, Andreas, Guiswe, Pierre, Lemr, Karel and Wiegrebe, Wolfgang (2001) On the Stereochemistry of Vincetene. Monatshefte fuer Chemie/Chemical Monthly 132 (6), pp. 765-768. Fulltext not available.

Alban, Susanne and Franz, Gerhard (2001) Partial Synthetic Glucan Sulfates as Potential New Antithrombotics: A Review. Biomacromolecules 2 (2), pp. 354-361. Fulltext not available.

Hansen, Ernil, Bucher, Michael, Jakob, Wolfgang, Lemberger, Peter and Kees, Frieder (2001) Pharmacokinetics of levofloxacin during continuous veno-venous hemofiltration. Intensive Care Medicine 27 (2), pp. 371-375. Fulltext not available.

Kees, F., Färber, L., Bucher, M., Mair, G., Mörike, K. and Grobecker, H. (2001) Pharmacokinetics of therapeutic doses of tropisetron in healthy volunteers. British Journal of Clinical Pharmacology 52 (6), pp. 705-707. Fulltext not available.

Vogelhuber, W., Rutunno, P., Magni, E., Gazzaniga, A. , Spruss, Thilo, Bernhardt, Günther, Buschauer, Armin and Goepferich, Achim (2001) Programmable biodegradable implants. Journal of Controlled Release 73 (1), pp. 75-88. Fulltext not available.

Höcherl, Klaus, Wolf, Konrad, Castrop, Hayo, Ittner, Karl, Bucher, Michael, Kees, Frieder, Grobecker, Horst and Kurtz, Armin (2001) Renocortical expression of renin and of cyclooxygenase-2 in response to angiotensin II AT 1 receptor blockade is closely coordinated but not causally linked. Pfl�gers Archiv European Journal of Physiology 442 (6), pp. 821-827. Fulltext not available.

Lu, L (2001) Retinal pigment epithelial cell adhesion on novel micropatterned surfaces fabricated from synthetic biodegradable polymers. Biomaterials 22 (3), pp. 291-297. Fulltext not available.

Iwasa, Kinuko, Moriyasu, Masataka, Tachibana, Yoko, Kim, Hye-Sook, Wataya, Yusuke, Wiegrebe, Wolfgang, Bastow, Kenneth F, Cosentino, L.Mark, Kozuka, Mutsuo and Lee, Kuo-Hsiung (2001) Simple Isoquinoline and Benzylisoquinoline Alkaloids as Potential Antimicrobial, Antimalarial, Cytotoxic, and Anti-HIV Agents. Bioorganic & Medicinal Chemistry 9 (11), pp. 2871-2884. Fulltext not available.

Käsbauer, Christian W, Paper, Dietrich H and Franz, Gerhard (2001) Sulfated β-(1→4)-galacto-oligosaccharides and their effect on angiogenesis. Carbohydrate Research 330 (3), pp. 427-430. Fulltext not available.

Rostom, Sherif A. F., Farghaly, Ahmed M., Soliman, Farid S. G., El-Semary, Mona M., Elz, Sigurd and Lehmann, Jochen (2001) Synthesis and 5-HT2A Antagonist Activity of Derivatives of the Novel Heterocycles Indolo[3,2-d]pyrrolo[3,2-g]azecine and Benzo[d]pyrrolo[3,2-g]azecine compared to the Benz[d]indolo[2,3-g]azecine Derivative LE 300. Archiv der Pharmazie 334 (7), pp. 241-247. Fulltext not available.

Mahboobi, Siavosh, Pongratz, Herwig, Hufsky, Harald, Hockemeyer, Jörg, Frieser, Markus, Lyssenko, Alexei, Paper, Dietrich H., Bürgermeister, Jutta, Böhmer, Frank-D., Fiebig, Heinz-Herbert, Burger, Angelika M., Baasner, Silke and Beckers, Thomas (2001) Synthetic 2-Aroylindole Derivatives as a New Class of Potent Tubulin-Inhibitory, Antimitotic Agents. Journal of Medicinal Chemistry 44 (26), pp. 4535-4553. Fulltext not available.

Meiers, Susanne, Kemény, Monika, Weyand, Ulrike, Gastpar, Robert, von Angerer, Erwin and Marko, Doris (2001) The Anthocyanidins Cyanidin and Delphinidin Are Potent Inhibitors of the Epidermal Growth-Factor Receptor. Journal of Agricultural and Food Chemistry 49 (2), pp. 958-962. Fulltext not available.

Schweikl, H., Schmalz, G. and Spruss, T. (2001) The Induction of Micronuclei in vitro by Unpolymerized Resin Monomers. Journal of Dental Research 80 (7), pp. 1615-1620. Fulltext not available.

Sazima, M., Vogel, S., do Prado, A. Lemes, de Oliveira, D. M., Franz, Gerhard and Sazima, I. (2001) The sweet jelly of Combretum lanceolatum flowers (Combretaceae): a cornucopia resource for bird pollinators in the Pantanal, western Brazil. Plant Systematics and Evolution 227, pp. 195-208. Fulltext not available.

Zacher, J., Burger, K.J., Färber, L., Gräve, M., Abberger, H. and Bertsch, K. (2001) Topisches Diclofenac Emulgel versus orales Ibuprofen in der Therapie der aktivierten Arthrose der Fingergelenke (Heberden- und/oder Bouchard-Arthrose) - Doppelblinde, kontrollierte, randomisierte Studie -. Aktuelle Rheumatologie 26 (1), pp. 7-14. Fulltext not available.

Diener, Hans Christoph, Ringelstein, Erich Bernd, von Kummer, Rüdiger, Langohr, Hans Dieter, Bewermeyer, Heiko, Landgraf, Helmut, Hennerici, Michael, Welzel, Dieter, Gräve, Michael, Brom, Joachim and Weidinger, Gottfried (2001) Treatment of Acute Ischemic Stroke With the Low-Molecular-Weight Heparin Certoparin. Stroke 32 (1), pp. 22-29. Fulltext not available.

Varga, B., Färber, L., Kohnen, R., Stratz, Th., Trocsanyi, M., Wild, J. and Müller, W. (2000) 4-wöchige Therapie mit dem 5-HT3-Rezeptor-Antagonisten Tropisetron bei der Fibromyalgie. Aktuelle Rheumatologie 25 (01/02), pp. 43-50. Fulltext not available.

Lee, Dong-Ung, Kang, So-Im, Yoon, Soo-Hong, Budesinsky, Milos, Kasal, Alexander, Mayer, Klaus K. and Wiegrebe, Wolfgang (2000) A New Steroidal Alkaloid from the Roots of Cynanchum caudatum. Planta Medica 66 (5), pp. 480-482. Fulltext not available.

Zabel, Manfred, Breu, Josef , Rau, Franz, Range, Klaus-Jürgen, Krey, Volker, Uffrecht, Anka and Buschauer, Armin (2000) Absolute configuration of (-)-4-(3,4-dichlorophenyl)-4-(2-pyridyl)butanoic acid: essential information to determine crucial steric feature of arpromidine-type histamine H_2 receptor agonists. Acta Crystallographica Section C 56, pp. 250-251. Fulltext not available.

Golob, Thomas, Biberger, Christian, Walter, Georg and von Angerer, Erwin (2000) Antiestrogenic Activities of 3,8-Dihydroxy-6,11-dihydrobenzo[a]carbazoles with Sulfur-Containing Side Chains. Archiv der Pharmazie 333 (9), pp. 305-311. Fulltext not available.

Lucke, Andrea, Teßmar, Jörg , Schnell, Edith, Schmeer, Georg and Göpferich, Achim (2000) Biodegradable poly(d,l-lactic acid)-poly(ethylene glycol)-monomethyl ether diblock copolymers: structures and surface properties relevant to their use as biomaterials. Biomaterials 21 (23), pp. 2361-2370. Fulltext not available.

Alban, Susanne and Franz, Gerhard (2000) Characterization of the Anticoagulant Actions of a Semisynthetic Curdlan Sulfate. Thrombosis Research 99 (4), pp. 377-388. Fulltext not available.

Joschek, S., Nies, B., Krotz, R. and Göpferich, A. (2000) Chemical and physicochemical characterization of porous hydroxyapatite ceramics made of natural bone. Biomaterials 21 (16), pp. 1645-1658. Fulltext not available.

Moser, C., Bernhardt, G., Michel, J., Schwarz, H. and Buschauer, A. (2000) Cloning and functional expression of the hNPY Y<sub>5</sub> receptor in human endometrial cancer (HEC-1B) cells. Canadian Journal of Physiology and Pharmacology 78 (2), pp. 134-142. Fulltext not available.

Kumar KC, S (2000) Depsides as non-redox inhibitors of leukotriene B4 biosynthesis and HaCaT cell growth, 2. Novel analogues of obtusatic acid. European Journal of Medicinal Chemistry 35 (4), pp. 405-411. Fulltext not available.

Schlemmer, Richard, Spruß, Thilo, Bernhardt, Günther and Schönenberger, Helmut (2000) Does [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]- dichloro-platinum(II) act as an immune response modifier? Part III: Progressively growing MXT-M-3,2 breast cancer stimulates the proliferation of phagocytes in B6D2F1 mice. Archiv der Pharmazie 333 (12), pp. 404-414. Fulltext not available.

Schlemmer, Richard, Spruß, Thilo, Bernhardt, Günther and Schönenberger, Helmut (2000) Does [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]- dichloroplatinum(II) act on the hormone-sensitive, murine breast cancer as a biological response modifier? Part 1: The MXT-M-3.2 breast cancer stimulates the growth of an identical second graft; [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]dichloroplat inum (II) inhibits this process. Archiv der Pharmazie 333 (2-3), pp. 69-71. Fulltext not available.

Schlemmer, Richard, Spruß, Thilo, Bernhardt, Günther and Schönenberger, Helmut (2000) Does [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]- dichloroplatinum(II) act on the hormone-sensitive, murine breast cancer as a biological response modifier? Part II. Studies on the influence of [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine] dichloroplatinum(II) on the specific immune defense in MXT-M-3,2 breast cancer bearing mice. Archiv der Pharmazie 333 (12), pp. 397-403. Fulltext not available.

Shafi, Shahida, Stepanova, Irina P, Fitzsimmons, C, Bowyer, D.E, Welzel, D and Born, G.V.R (2000) Effects of reserpine on expression of the LDL receptor in liver and on plasma and tissue lipids, low density lipoprotein and fibrinogen in rabbits in vivo. Atherosclerosis 149 (2), pp. 267-275. Fulltext not available.

Schönberger, Johann, Bauer, Johann, Spruß, Thilo, Weber, Gerhard, Chahoud, Ibrahim, Eilles, Christoph and Grimm, Daniela (2000) Establishment and characterization of the follicular thyroid carcinoma cell line ML-1. Journal of Molecular Medicine 78 (2), pp. 102-110. Fulltext not available.

Schulz, Michaela B and Daniels, Rolf (2000) Hydroxypropylmethylcellulose (HPMC) as emulsifier for submicron emulsions: influence of molecular weight and substitution type on the droplet size after high-pressure homogenization. European Journal of Pharmaceutics and Biopharmaceutics 49 (3), pp. 231-236. Fulltext not available.

Ammon, , Treiber, , Kees, and Klotz, (2000) Influence of age on the steady state disposition of drugs commonly used for the eradication of Helicobacter pylori. Alimentary Pharmacology & Therapeutics 14 (6), pp. 759-766. Fulltext not available.

Kumar, Sunil, Ziereis, Klaus, Wiegrebe, Wolfgang and Müller, Klaus (2000) Medicinal plants from Nepal: evaluation as inhibitors of leukotriene biosynthesis. Journal of Ethnopharmacology 70 (3), pp. 191-195. Fulltext not available.

Kees, , Holstege, , Ittner, , Zimmermann, , Lock, , Schölmerich, and Grobecker, (2000) Pharmacokinetic interaction between proton pump inhibitors and roxithromycin in volunteers. Alimentary Pharmacology & Therapeutics 14 (4), pp. 407-412. Fulltext not available.

Strehl, Egid and Kees, Frieder (2000) Pharmacological Properties of Parenteral Cephalosporins. Drugs 59 (Supple), pp. 9-18. Fulltext not available.

Dove, Stefan, Michel, Martin C., Knieps, Sebastian and Buschauer, Armin (2000) Pharmacology and quantitative structure-activity relationships of imidazolylpropylguanidines with mepyramine-like substructures as non-peptide neuropeptide Y Y<sub>1</sub> receptor antagonists. Canadian Journal of Physiology and Pharmacology 78 (2), pp. 108-115. Fulltext not available.

Teller, S (2000) Pyrrolo[3,4-c]-β-carboline-diones as a novel class of inhibitors of the platelet-derived growth factor receptor kinase. European Journal of Medicinal Chemistry 35 (4), pp. 413-427. Fulltext not available.

Aiglstorfer, Iris, Hendrich, Ingo, Moser, Christiane, Bernhardt, Günther, Dove, Stefan and Buschauer, Armin (2000) Structure-Activity Relationships of Neuropeptide Y Y_1 Receptor Antagonists Related to BIBP 3226,. Bioorganic & Medicinal Chemistry Letters 10 (14), pp. 1597-1600. Fulltext not available.

Mahboobi, Siavosh, Dechant, Irene, Reindl, Hans, Pongratz, Herwig, Popp, Alfred and Schollmeyer, Dieter (2000) Synthesis of bis(indolylmaleimide) macrocycles. Journal of Heterocyclic Chemistry 37 (2), pp. 307-329. Fulltext not available.

Mahboobi, Siavosh, Eluwa, Stella, Koller, Markus, Popp, Alfred and Schollmeyer, Dieter (2000) Synthesis of pyrrolo[3′,4′:2,3]azepino[4,5,6‐cd]indole‐8,10‐diones. Journal of Heterocyclic Chemistry 37 (5), pp. 1177-1185. Fulltext not available.

Mahboobi, Siavosh, Koller, Markus and Schollmeyer, Dieter (2000) Synthesis of the Racemates of the b-Carboline Alkaloid Chrysotricine and its Diastereomer. Monatshefte für Chemie/Chemical Monthly 131 (4), 0383-0392. Fulltext not available.

Ittner, K.P., Zimmermann, M., Bucher, M., Gessele, W., Kees, F., Krämer, B.K. and Grobecker, H.F. (2000) The effect of urapidil and ramipril on hyperglycemia in streptozotocin diabetic rats. Naunyn-Schmiedeberg's Archives of Pharmacology 361 (1), pp. 92-97. Fulltext not available.

Gust, Ronald, Faderl, Michael and Schönenberger, Helmut (2000) [Aqua-1-(2,6-dichloro-4-hydroxyphenyl)-2-phenylethylenediamine] sulfatoplatinum(II) complexes with variable substituents in the 2-phenyl ring. Journal of Cancer Research and Clinical Oncology 126 (11), pp. 647-654. Fulltext not available.

Vogl, H., Paper, D. H. and Franz, Gerhard (1999) Preparation of a sulfated linear (1→4)-β-d-galactan with variable degrees of sulfation. Carbohydrate Polymers 41, pp. 185-190. Fulltext not available.

Klinker, J. F., Schwaner, I., Offermanns, S., Hagelüken, A. and Seifert, Roland (1994) Differential activation of dibutyryl cAMP-differentiated HL-60 human leukemia cells by chemoattractants. Biochemical pharmacology 48 (10), pp. 1857-1864.

Wenzel-Seifert, K., Schächtele, C., Hummel, R., Grünbaum, L. and Seifert, Roland (1994) Evidence that inhibition of phorbol ester-induced superoxide anion formation by cyclosporin A in phagocytes is not mediated by direct inhibition of protein kinase C. Biochemical pharmacology 48 (5), pp. 859-864.

Seifert, Roland, Grünbaum, L. and Schultz, Günter (1994) Histamine H1-receptors in HL-60 monocytes are coupled to Gi-proteins and pertussis toxin-insensitive G-proteins and mediate activation of Ca2+ influx without concomitant Ca2+ mobilization from intracellular stores. Naunyn-Schmiedeberg's archives of pharmacology 349 (4), pp. 355-361.

Musgrave, I. F. and Seifert, Roland (1994) Human neutrophils and HL-60 cells do not possess alpha 2-adrenoceptors. Biochemical pharmacology 47 (2), pp. 233-239.

Hagelüken, A., Grünbaum, L., Nürnberg, B., Harhammer, R., Schunack, W. and Seifert, Roland (1994) Lipophilic beta-adrenoceptor antagonists and local anesthetics are effective direct activators of G-proteins. Biochemical pharmacology 47 (10), pp. 1789-1795.

Musgrave, I. F., Seifert, Roland and Schultz, Günter (1994) Maitotoxin activates cation channels distinct from the receptor-activated non-selective cation channels of HL-60 cells. The Biochemical journal 301 ( Pt 2, pp. 437-441.

Klinker, J. F., Hagelüken, A., Grünbaum, L., Heilmann, I., Nürnberg, B., Harhammer, R., Offermanns, S., Schwaner, I., Ervens, J., Wenzel-Seifert, K., Müller, T. and Seifert, Roland (1994) Mastoparan may activate GTP hydrolysis by Gi-proteins in HL-60 membranes indirectly through interaction with nucleoside diphosphate kinase. The Biochemical journal 304 ( Pt 2, pp. 377-383.

Wenzel-Seifert, K., Schächtele, C. and Seifert, Roland (1994) N-protein kinase C isoenzymes may be involved in the regulation of various neutrophil functions. Biochemical and biophysical research communications 200 (3), pp. 1536-1543.

Blunk, Torsten (1994) Plasmaproteinadsorption auf kolloidalen Arzneistoffträgern. Analytik, Korrelation mit Oberflächeneigenschaften, Implikationen für das Drug Targeting. PhD, Kiel, Univ..

Naim, M., Seifert, Roland, Nürnberg, B., Grünbaum, L. and Schultz, Günter (1994) Some taste substances are direct activators of G-proteins. The Biochemical journal 297 ( Pt 3, pp. 451-454.

Berger, M., Offermanns, S., Seifert, Roland and Schultz, Günter (1994) Synthetic lipopeptide Pam3CysSer(Lys)4 is an effective activator of human platelets. The American journal of physiology 266 (6 Pt 1), C1684-C1691.

Seifert, Roland, Hagelüken, A., Höer, A., Höer, D., Grünbaum, L., Offermanns, S., Schwaner, I., Zingel, V., Schunack, W. and Schultz, Günter (1994) The H1 receptor agonist 2-(3-chlorophenyl)histamine activates Gi proteins in HL-60 cells through a mechanism that is independent of known histamine receptor subtypes. Molecular Pharmacology 45 (4), pp. 578-586.

Tsang, K. W., Roberts, P., Read, R. C., Kees, Frieder, Wilson, R. and Cole, P. J. (1994) The concentrations of clarithromycin and its 14-hydroxy metabolite in sputum of patients with bronchiectasis following single dose oral administration. The Journal of antimicrobial chemotherapy 33 (2), pp. 289-297.

Honeybourne, D., Kees, Frieder K., Andrews, J. M., Baldwin, D. and Wise, R. (1994) The levels of clarithromycin and its 14-hydroxy metabolite in the lung. The European respiratory journal 7 (7), pp. 1275-1280.

Blunk, Torsten, Mak, E. and Müller, R. H. (1993) Characterization of Colloidal Drug Carriers. Die pharmazeutische Industrie : pharmind 55 (6), pp. 612-615.

Sedlmayr, T., Petersen, F., Raasch, W. and Kees, Frieder K. (1993) Clarithromycin, ein neues Makrolid-Antibiotikum. Wirksamkeit bei puerperalen Infektionen und Übertritt in die Muttermilch [Clarithromycin, a new macrolide antibiotic. Effectiveness in puerperal infections and pharmacokinetics in breast milk]. Geburtshilfe und Frauenheilkunde 53 (7), pp. 488-491.

Blunk, Torsten, Hochstrasser, D. F., Sanchez, J. C., Müller, B. W. and Müller, R. H. (1993) Colloidal carriers for intravenous drug targeting: plasma protein adsorption patterns on surface-modified latex particles evaluated by two-dimensional polyacrylamide gel electrophoresis. Electrophoresis 14 (12), pp. 1382-1387.

Wenzel-Seifert, Katharina and Seifert, Roland (1993) Cyclosporin H is a potent and selective formyl peptide receptor antagonist. Comparison with N-t-butoxycarbonyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L- leucyl-L-phenylalanine and cyclosporins A, B, C, D, and E. The Journal of Immunology 150 (10), pp. 4591-4599.

Bernhardt, Günther (1993) Entwicklung und Anwendung moderner Testverfahren zur Auffindung und Optimierung der Antitumorwirkung neuartiger Diphenylethylendiaminplatin(II)-Komplexe. Habilitation, Regensburg, Universität.

Klinker, J. F., Höer, A., Schwaner, I., Offermanns, S., Wenzel-Seifert, Katharina and Seifert, Roland (1993) Lipopeptides activate Gi-proteins in dibutyryl cyclic AMP-differentiated HL-60 cells. The Biochemical journaL 296 ( Pt 1, pp. 245-251.

Wenzel-Seifert, Katharina and Seifert, Roland (1993) Partial inhibition of human neutrophil activation by FK-506 at supratherapeutic concentrations. Naunyn-Schmiedeberg's archives of pharmacology 348 (1), pp. 7-13.

Grobecker, H. F. and Kees, Frieder K. (1993) Pharmacokinetic parameters and haemodynamic actions of midodrine in young volunteers. International angiology : a journal of the International Union of Angiology 12 (2), pp. 119-124.

Musgrave, I. F., Genieser, H. G., Maronde, E. and Seifert, Roland (1993) Preparations of Rp-cyclic adenosine 3',5'-phosphorothioate (Rp-cAMPS) can contain biologically active amounts of adenosine. FEBS letters 318 (3), pp. 227-230.

Rudt, S., Blunk, Torsten and Müller, R. H. (1992) Quantification of Cell Subpopulations, Fractions of Dead
Cells and Debris in Cell Suspensions by Laser Diffractometry. Die pharmazeutische Industrie 54 (11), pp. 966-969.

Müller, R. H., Lherm, C., Herbort, J., Blunk, Torsten and Couvreur, P. (1992) Alkylcyanoacrylate drug carriers: I. Physicochemical characterization of nanoparticles with different alkyl chain length. International Journal of Pharmaceutics 84 (1), pp. 1-11.

Dominiak, P., Kees, Frieder K., Welzel, D. and Grobecker, H. (1992) Cardiovascular parameters and catecholamines in volunteers during passive orthostasis. Influence of antihypotensive drugs. Arzneimittel-Forschung 42 (5), pp. 637-642.

Krautwurst, D., Seifert, Roland, Hescheler, J. and Schultz, Günter (1992) Formyl peptides and ATP stimulate Ca2+ and Na+ inward currents through non-selective cation channels via G-proteins in dibutyryl cyclic AMP-differentiated HL-60 cells. Involvement of Ca2+ and Na+ in the activation of beta-glucuronidase release and superoxide production. The Biochemical journal 288 ( Pt 3, pp. 1025-1035.

Klinz, F. J., Seifert, Roland, Schwaner, I., Gausepohl, H., Frank, R. and Schultz, Günter (1992) Generation of specific antibodies against the rap1A, rap1B and rap2 small GTP-binding proteins. Analysis of rap and ras proteins in membranes from mammalian cells. European journal of biochemistry 207 (1), pp. 207-213.

Seifert, Roland, Höer, Ariane, Offermann, Stefan, Buschauer, Armin and Schunack, Walter (1992) Histamine increases Ca^2+ in dibutyryl cyclic AMP-differentiated HL-60 cells via H_1-receptors and is an incomplete secretagogue. Mol. Pharmacol. 42, pp. 227-234.

Seifert, Roland, Höer, Ariane, Schwaner, Ingo and Buschauer, Armin (1992) Histamine increases cytosolic Ca^2+ in HL-60 promyelocytes predominantly via H_2-receptors with an unique agonist/antagonist profile and induces functional differentiation. Molecular Pharmacology 42, pp. 235-241.

Seifert, Roland, Serke, S., Huhn, D., Bessler, W. G., Hauschildt, S., Metzger, J., Wismüller, K. H. and Jung, G. (1992) Incomplete functional differentiation of HL-60 leukemic cells by synthetic lipopeptides. Partial inhibition by pertussis toxin of enhanced superoxide formation. European journal of biochemistry / FEBS 203 (1-2), pp. 143-151.

Offermanns, S., Seifert, Roland, Metzger, J. W., Jung, G., Lieberknecht, A., Schmidt, U. and Schultz, Günter (1992) Lipopeptides are effective stimulators of tyrosine phosphorylation in human myeloid cells. Biochemical Journal 282 ( Pt 2, pp. 551-7.

Ervens, J. and Seifert, Roland (1992) Molsidomine inhibits the chemoattractant-induced respiratory burst in human neutrophils via a no-independent mechanism. Biochemical pharmacology 44 (4), pp. 637-644.

Kees, Frieder K. (1992) Orale Cephalosporine [Oral cephalosporins]. Medizinische Monatsschrift für Pharmazeuten 15 (1), pp. 2-10.

Schwaner, I., Seifert, Roland and Schultz, Günter (1992) Receptor-mediated increases in cytosolic Ca2+ in the human erythroleukaemia cell line involve pertussis toxin-sensitive and -insensitive pathways. The Biochemical journal 281 ( Pt 2, pp. 301-307.

Kees, Frieder K., Raasch, W. and Grobecker, H. F. (1992) Strukturelle Charakterisierung eines unbekannten Metaboliten von Ciprofloxacin [Structural characterization of an unknown metabolite of ciprofloxacin]. Arzneimittel-Forschung 42 (4), pp. 570-575.

Schwaner, I., Seifert, Roland and Schultz, Günter (1992) The prostacyclin analogues, cicaprost and iloprost, increase cytosolic Ca2+ concentration in the human erythroleukemia cell line, HEL, via pertussis toxin-insensitive G-proteins. Eicosanoids 5 Suppl, S10-512. Fulltext not available.

Kees, Frieder K., Lukassek, U., Naber, K. G. and Grobecker, H. (1991) Comparative investigations on the bioavailability of cefuroxime axetil. Arzneimittel-Forschung 41 (8), pp. 843-846.

Bernhardt, Günther, Spruss, Thilo and Schönenberger, Helmut (1991) Einsatz menschlicher Tumorzellkulturen als Testmodelle bei der Entwicklung von Wirkstoffen für die Krebstherapie. Forum für interdisziplinäre Forschung : FIF 4, pp. 24-28.

Seifert, Roland and Schultz, Günter (1991) The superoxide- forming NADPH oxidase of phagocytes: an enzyme system regulated by multiple mechanisms. Reviews of physiology, biochemistry, and pharmacology, 117. Springer, Berlin. ISBN 3-540-53663-9, 0-387-53663-9.

Seifert, Roland, Schultz, Günter, Richter-Freund, M., Metzger, J., Wiesmüller, K. H., Jung, G., Bessler, W. G. and Hauschildt, S. (1990) Activation of superoxide formation and lysozyme release in human neutrophils by the synthetic lipopeptide Pam3Cys-Ser-(Lys)4. Involvement of guanine-nucleotide-binding proteins and synergism with chemotactic peptides. The Biochemical journal 267 (3), pp. 795-802.

Jungblut, P. R. and Seifert, Roland (1990) Analysis by high-resolution two-dimensional electrophoresis of differentiation-dependent alterations in cytosolic protein pattern of HL-60 leukemic cells. Journal of biochemical and biophysical methods 21 (1), pp. 47-58.

Burde, Rahel, Buschauer, Armin and Seifert, Roland (1990) Characterization of histamine H_2-receptors in human neutrophils with a series of guanidine analogues of impromidine: Are cell type-specific H_2-receptors involved in the regulation of NADPH oxidase? Naunyn-Schmiedeberg's Archives of Pharmacology 341, pp. 455-461.

Kees, Frieder K., Raasch, W., Steger, M. and Grobecker, H. (1990) High-performance liquid chromatographic assay for cefotiam and d3-cefotiam in human serum. Journal of Chromatography B 525 (2), pp. 484-489.

Wenzel-Seifert, Katharina and Seifert, Roland (1990) Nucleotide-, chemotactic peptide- and phorbol ester-induced exocytosis in HL-60 leukemic cells. Immunobiology 181 (4-5), pp. 298-316.

Kees, Frieder K. and Naber, K. G. (1990) Pharmakokinetik von Cefixim bei Probanden und ein Literaturvergleich mit neuen Ester Prodrug Cephalosporinen [Pharmacokinetics of cefixime in volunteers and a literature comparison with the new ester prodrug cephalosporins]. Infection 18 Suppl 3, S150-S154.

Kees, Frieder K., Naber, K. G., Sigl, G., Ungethüm, W. and Grobecker, H. F. (1990) Relative bioavailability of three cefixime formulations. Arzneimittel-Forschung 40 (3), pp. 293-297.

Korting, H. C., Schäfer-Korting, M., Kees, Frieder K., Lukacs, A. and Grobecker, H. (1990) Skin tissue fluid levels of cefotiam in healthy man following oral cefotiam hexetil. European journal of clinical pharmacology 39 (1), pp. 33-36.

Kees, Frieder K., Dehner, R., Dittrich, W., Raasch, W. and Grobecker, H. F. (1990) Untersuchungen zur Bioverfügbarkeit von Doxycy [The bioavailability of doxycycline]. Arzneimittel-Forschung 40 (9), pp. 1039-1043.

Seifert, Roland, Burde, R. and Schultz, Günter (1989) Activation of NADPH oxidase by purine and pyrimidine nucleotides involves G proteins and is potentiated by chemotactic peptides. The Biochemical journal 259 (3), pp. 813-819.

Engel, K. J., Schmidt, W., Sonntag, H. G. and Kees, Frieder K. (1989) Comparative clinical and pharmacokinetic aspects of cefotetan versus cefoxitin plus metronidazole in vaginal hysterectomy. Journal of chemotherapy 1 (4 Supl), pp. 1053-1056. Fulltext not available.

Seifert, Roland, Jungblut, P. and Schultz, Günter (1989) Differential expression of cytosolic activation factors for NADPH oxidase in HL-60 leukemic cells. Biochemical and biophysical research communications 161 (3), pp. 1109-1117.

Naber, K. G., Sörgel, F., Kees, Frieder K., Schumacher, H., Sigl, G., Zürcher, J. and Berger, S. (1989) Enoxacin-Konzentrationen in der Samenflüssigkeit, im Prostatasekret und im Prostataadenomgewebe nach oraler Gabe oder intravenöser Infusion [Enoxacin concentration in seminal fluid, in prostate secretions and in prostatic adenoma tissue following oral administration or intravenous infusion]. Infection 17 Suppl 1, S30-S66.

Schmidt, H. H., Seifert, Roland and Böhme, E. (1989) Formation and release of nitric oxide from human neutrophils and HL-60 cells induced by a chemotactic peptide, platelet activating factor and leukotriene B4. FEBS letters 244 (2), pp. 357-360.

Rudolph, U., Koesling, D., Hinsch, K. D., Seifert, Roland, Bigalke, M., Schultz, Günter and Rosenthal, W. (1989) G-protein alpha-subunits in cytosolic and membranous fractions of human neutrophils. Molecular and cellular endocrinology 63 (1-2), pp. 143-153.

Burde, Rahel, Seifert, Roland, Buschauer, Armin and Schultz, Günther (1989) Histamine inhibits activation of human neutrophils and HL-60 leukemic cells via H_2-receptors. Naunyn-Schmiedeberg's archives of pharmacology 340, pp. 671-678.

Seifert, Roland and Schultz, Günter (1989) Involvement of pyrimidinoceptors in the regulation of cell functions by uridine and by uracil nucleotides. Trends in pharmacological sciences 10 (9), pp. 365-369.

Seifert, Roland, Burde, R. and Schultz, Günter (1989) Lack of effect of opioid peptides, morphine and naloxone on superoxide formation in human neutrophils and HL-60 leukemic cells. Naunyn-Schmiedeberg's archives of pharmacology 340 (1), pp. 101-106.

Kees, Frieder K., Naber, K. G., Meyer, G. P. and Grobecker, H. (1989) Pharmacokinetics of ciprofloxacin in elderly patients. Arzneimittel-Forschung 39 (4), pp. 523-527.

Naber, K. G., Sörgel, F., Kees, Frieder K., Jaehde, U. and Schumacher, H. (1989) Pharmacokinetics of ciprofloxacin in young (healthy volunteers) and elderly patients, and concentrations in prostatic fluid, seminal fluid, and prostatic adenoma tissue following intravenous administration. The American journal of medicine 87 (5supl1), S57-S59.

Seifert, Roland, Wenzel, Katharina, Eckstein, F. and Schultz, Günter (1989) Purine and pyrimidine nucleotides potentiate activation of NADPH oxidase and degranulation by chemotactic peptides and induce aggregation of human neutrophils via G proteins. European journal of biochemistry / FEBS 181 (1), pp. 277-285.

Kujath, P., Düsel, W., Bruch, H. P. and Kees, Frieder K. (1989) The pharmacokinetic properties of cefotetan and its relevance for prophylaxis in elective colorectal surgery. Journal of chemotherapy 1 (4 Supl), pp. 1002-1004. Fulltext not available.

Seifert, Roland, Schächtele, C., Rosenthal, W. and Schultz, Günter (1988) Activation of protein kinase C by cis- and trans-fatty acids and its potentiation by diacylglycerol. Biochemical and biophysical research communications 154 (1), pp. 20-26.

Engel, K. J., Schmidt, W., Sonntag, H. G. and Kees, Frieder K. (1988) Comparative clinical and pharmacokinetic aspects of cefotetan versus cefoxitin plus metronidazole in vaginal hysterectomy. Chemioterapia 7 (4), pp. 256-260. Fulltext not available.

Naber, K. G., Sörgel, F., Kees, Frieder K., Schumacher, H., Metz, R. and Grobecker, H. (1988) In-vitro activity of fleroxacin against isolates causing complicated urinary tract infections and concentrations in seminal and prostatic fluid and in prostatic adenoma tissue. The Journal of antimicrobial chemotherapy 22 Suppl D, pp. 199-207.

Kees, Frieder K., Naber, K. G., Schumacher, H. and Grobecker, H. (1988) Penetration of fleroxacin into prostatic secretion and prostatic adenoma tissue. Chemotherapy 34 (6), pp. 437-443. Fulltext not available.

Schächtele, C., Seifert, Roland and Osswald, H. (1988) Stimulus-dependent inhibition of platelet aggregation by the protein kinase C inhibitors polymyxin B, H-7 and staurosporine. Biochemical and biophysical research communications 151 (1), pp. 542-547.

Seifert, Roland and Schächtele, C. (1988) Studies with protein kinase C inhibitors presently available cannot elucidate the role of protein kinase C in the activation of NADPH oxidase. Biochemical and biophysical research communications 152 (2), pp. 585-592.

Kujath, P., Düsel, W., Bruch, H. P. and Kees, Frieder K. (1988) The pharmacokinetic properties of cefotetan and its relevance for prophylaxis in elective colorectal surgery. Chemioterapia 7 (4), pp. 229-232. Fulltext not available.

Seifert, Roland, Rosenthal, W., Schultz, Günter, Wieland, T., Gierschick, P. and Jakobs, K. H. (1988) The role of nucleoside-diphosphate kinase reactions in G protein activation of NADPH oxidase by guanine and adenine nucleotides. European journal of biochemistry / FEBS 175 (1), pp. 51-55.

Seifert, Roland, Schächtele, C. and Schultz, Günter (1987) Activation of protein kinase C by cis- and trans-octadecadienoic acids in intact human platelets and its potentiation by diacylglycerol. Biochemical and biophysical research communications 149 (2), pp. 762-768.

Naber, K., Kees, Frieder K., Denk, K., Bauernfeind, A. and Grobecker, H. (1987) Carumonam versus ceftazidime: in vitro activity, pharmacokinetics in elderly patients, safety and therapeutic efficacy in the treatment of complicated urinary tract infections. Chemioterapia 6 (2 Supl), pp. 517-518. Fulltext not available.

Seifert, Roland and Schultz, Günter (1987) Fatty-acid-induced activation of NADPH oxidase in plasma membranes of human neutrophils depends on neutrophil cytosol and is potentiated by stable guanine nucleotides. European journal of biochemistry / FEBS 162 (3), pp. 563-569.

Naber, K. G., Adam, D. and Kees, Frieder K. (1987) In vitro activity and concentrations in serum, urine, prostatic secretion and adenoma tissue of ofloxacin in urological patients. Drugs 34 Suppl 1, S44-S50. Fulltext not available.

Seifert, Roland and Schultz, Günter (1987) Reversible activation of NADPH oxidase in membranes of HL-60 human leukemic cells. Biochemical and biophysical research communications 146 (3), pp. 1296-1302.

Kees, Frieder K., Dominiak, P. and Grobecker, H. (1987) Untersuchungen zur Bioverfügbarkeit von Heptaminol bei Probanden [Bioavailability of heptaminol in healthy subjects]. Arzneimittel-Forschung 37 (10), pp. 1182-1185.

Grobecker, H., Kees, Frieder K., Linden, M., Schrader, E. and Welte, S. (1987) Untersuchungen zur Bioverfügbarkeit von Midodrin und 2,5- Dimethoxyphenyl-ß-aminoethanol-hydrochlorid [The bioavailability of midodrin and alpha-2,5-dimethoxyphenyl-beta-aminoethanol hydrochloride]. Arzneimittel-Forschung 37 (4), pp. 447-450.

Dominiak, P., Kees, Frieder K. and Grobecker, H. (1986) Circulating and tissue catecholamines in rats with chronic neurogenic hypertension. Basic research in cardiology 81 (1), pp. 20-28.

Seifert, Roland, Rosenthal, W. and Schultz, Günter (1986) Guanine nucleotides stimulate NADPH oxidase in membranes of human neutrophils. FEBS letters 205 (1), pp. 161-165.

Bernhardt, Günther (1986) Hochdruckuntersuchungen an thermophilen Bakterien. PhD, Regensburg, Universität.

Martinez, C., Dominiak, P., Kees, Frieder K. and Grobecker, H. (1986) Inhibition of monoamine oxidase by viloxazine in rats. Arzneimittel-Forschung 36 (5), pp. 800-803.

Seifert, Roland (1986) Nikotinamidmethylierung in normalen Geweben und Tumorzellen von Ratte und Maus. PhD, Berlin, Freie Universität.

Naber, K. G., Dette, G. A., Kees, Frieder K., Knothe, H. and Grobecker, H. (1986) Pharmacokinetics, in-vitro activity, therapeutic efficacy and clinical safety of aztreonam vs. cefotaxime in the treatment of complicated urinary tract infections. The Journal of antimicrobial chemotherapy 17 (4), pp. 517-527.

Grobecker, H., Gessler, I., Delius, W., Dominiak, P. and Kees, Frieder K. (1985) Effect of ketanserin on hemodynamics, plasma-catecholamine concentrations, and serotonin uptake by platelets in volunteers and patients with congestive heart failure. Journal of cardiovascular pharmacology 7, Suppl 7, S102-S104.

Kees, Frieder K., Naber, K. G., Bartoschik-Wich, B., Stockmann, P., Meyer, G. P. and Grobecker, H. (1985) High-performance liquid chromatography analysis of mezlocillin, piperacillin, their degradation products, and of ioxitalamic acid in plasma and urine of healthy volunteers. Arzneimittel-Forschung 35 (7), pp. 1099-1104.

Dominiak, P., Kees, Frieder K. and Grobecker, H. (1985) Sympathoadrenal dysfunction in rats with chronic neurogenic hypertension. European journal of pharmacology 107 (2), pp. 263-266.

Dominiak, P., Kees, Frieder K. and Grobecker, H. (1984) Changes in peripheral and central catecholaminergic and serotoninergic neurons of rats after acute and subacute administration of nicotine. Klinische Wochenschrift. Supplementum 62 Suppl 2, pp. 76-80. Fulltext not available.

Kees, Frieder K., Grobecker, H. and Naber, K. G. (1984) High-performance liquid chromatographic analysis of cefotetan epimers in human plasma and urine. Journal of Chromatography B 305 (2), pp. 363-371.

Schleicher, E. D., Kees, Frieder K. and Wieland, O. H. (1983) Analysis of total urinary catecholamines by liquid chromatography: methodology, routine experience and clinical interpretations of results. Clinica chimica acta 129 (3), pp. 295-302.

Kees, Frieder K., Strehl, E., Dominiak, P., Grobecker, H., Seeger, K., Seidel, G., Neuhaus, B. and Safrany, L. (1983) Cefotaxime and desacetyl cefotaxime in human bile. Infection 11 (2), pp. 118-120.

Naber, K. G., Kees, Frieder K. and Grobecker, H. (1983) Ceftazidime: pharmacokinetics in young volunteers versus elderly patients and therapeutic efficacy with complicated urinary tract infections. The Journal of antimicrobial chemotherapy 12 Suppl A, pp. 41-45.

Kees, Frieder K., Strehl, E., Seeger, K., Seidel, G., Dominiak, P. and Grobecker, H. (1981) Comparative determination of cefotaxime and desacetyl cefotaxime in serum and bile by bioassay and high-performance liquid chromatography. Arzneimittel-Forschung 31 (2), pp. 362-365.

Kees, Frieder K. (1976) Thiaziridindioxide, Thiadiaziridindioxide und ein Beitrag zur Staudinger-Pfenninger-Reaktion. PhD, Univ. Würzburg. Fulltext not available.

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