Number of items at this level: 1160.
Nothofer, Stefanie,
Haselbeck-Koebler, Michael,
Zeitlinger, Markus,
Dorn, Christoph 
,
Petroff, David,
Wrigge, Hermann,
Dumps, Christian,
Heller, Axel R. and
Simon, Philipp
(2025)
Surgical Antibiotic Prophylaxis Dosing in Adult Patients with Obesity: A Comprehensive Review of Pharmacokinetic and Pharmacodynamic Data.
Anesthesiology 142 (5), pp. 929-948.
Fulltext not available.
Stommel, Alexandra-Maria 
,
Matzneller, Peter,
al Jalali, Valentin,
Wulkersdorfer, Beatrix,
Lackner, Edith,
Mueller, Matthias,
Dorn, Christoph 
,
Holzer, Michael and
Zeitlinger, Markus
(2025)
Impact of Hypothermic Temperature Control on Plasma and Soft Tissue Pharmacokinetics of Penicillin/Beta-Lactamase Inhibitor Combinations in Patients Resuscitated After Cardiac Arrest.
Clinical Pharmacokinetics.
Lier, Constantin,
Kees, Frieder 
,
Witowski, Andrea,
Rahmel, Tim,
Pockes, Steffen 
and
Dorn, Christoph 
(2025)
Simultaneous determination of ceftazidime and avibactam in patients by isocratic ion-pair liquid chromatography with photometric detection.
Journal of Chromatography Open 7, p. 100212.
Bindellini, Davide,
Simon, Philipp,
Busse, David,
Michelet, Robin,
Petroff, David,
Aulin, Linda B. S.,
Dorn, Christoph 
,
Zeitlinger, Markus,
Huisinga, Wilhelm,
Wrigge, Hermann and
Kloft, Charlotte
(2025)
Evaluation of the need for dosing adaptations in obese patients for surgical antibiotic prophylaxis: a model-based analysis of cefazolin pharmacokinetics.
British Journal of Anaesthesia.
Gonzalez-Valerio, Carlos,
Peregrina-Lucano, Alejandro A. 
,
Manríquez-González, Ricardo,
Pérez-Fonseca, Aida A.,
Robledo-Ortíz, Jorge R.,
Shenderovich, Ilya G. 
and
Gómez-Salazar, Sergio
(2024)
Color Compounds Removal from Tequila Vinasses Using Silica Gel Adsorbents Functionalized with Thiol Moieties: Equilibrium and Kinetics Studies.
Molecules 29 (24), p. 5910.
Becker, Jasmin,
Ellerkmann, Clara S.,
Schmelzer, Hannah,
Hermann, Christian,
Lützel, Kyra,
Gudermann, Thomas,
Konrad, David B.,
Trauner, Dirk,
Storch, Ursula 
and
Mederos y Schnitzler, Michael
(2024)
Optical Control of TRPM8 Channels with Photoswitchable Menthol.
Angewandte Chemie International Edition.
Dejaco, Alexander 
,
Dorn, Christoph 
,
Lier, Constantin,
Fleischmann, Daniel,
Kratzer, Alexander,
Habler, Katharina,
Paal, Michael,
Gruber, Michael 
,
Rosenberger, Johanna and
Kees, Martin G. 
(2024)
Target-controlled dialysis for antibiotics (TCD-ABx).
Intensive Care Medicine Experimental 12, p. 108.
Witowski, Andrea,
Palmowski, Lars,
Minichmayr, Iris K.,
Zeitlinger, Markus,
Dorn, Christoph 
,
Lier, Constantin,
Adamzik, Michael,
Nowak, Hartmuth and
Rahmel, Tim
(2024)
Concentrations of ceftazidime and avibactam in bile fluid—a prospective phase IIb study.
Journal of Antimicrobial Chemotherapy 79 (12), pp. 3297-3302.
Fulltext not available.
Sanz-Codina, Maria,
van Os, Wisse,
Pham, Anh Duc,
Jorda, Anselm,
Wölf-Duchek, Michael,
Bergmann, Felix,
Lackner, Edith,
Lier, Constantin,
Coen van Hasselt, J. G.,
Minichmayr, Iris K.,
Dorn, Christoph 
,
Zeitlinger, Markus and
al Jalali, Valentin
(2024)
Target-site cefiderocol pharmacokinetics in soft tissues of healthy volunteers.
Journal of Antimicrobial Chemotherapy 79 (12), pp. 3281-3288.
Unterholzner, Anna,
Kuck, Katrin,
Weinzierl, Anna,
Lipowicz, Bartosz and
Heilmann, Jörg
(2024)
An Unprecedented 4,8-Cycloeudesmane, Further New Sesquiterpenoids, a Triterpene, Steroids, and a Lignan from the Resin of Commiphora myrrha and Their Anti-Inflammatory Activity In Vitro.
Molecules 29 (18), p. 4315.
Schorr, Kathrin,
Chen, Xinyu,
Sasaki, Takanori,
Arias-Loza, Anahi Paula,
Lang, Johannes,
Higuchi, Takahiro and
Goepferich, Achim 
(2024)
Rethinking Thin-Layer Chromatography for Screening Technetium-99m Radiolabeled Polymer Nanoparticles.
ACS Pharmacology & Translational Science 7 (9), pp. 2604-2611.
Schatz, Lea Marie,
Greppmair, Sebastian,
Kunzelmann, Alexandra K.,
Starp, Johannes,
Brinkmann, Alexander,
Roehr, Anka,
Frey, Otto,
Hagel, Stefan,
Dorn, Christoph 
,
Zoller, Michael,
Scharf, Christina,
Wicha, Sebastian G. and
Liebchen, Uwe
(2024)
Predictive performance of multi-model approaches for model-informed precision dosing of piperacillin in critically ill patients.
International Journal of Antimicrobial Agents 64 (4), p. 107305.
Brummer, Christina,
Singer, Katrin,
Brand, Almut,
Bruss, Christina,
Renner, Kathrin,
Herr, Wolfgang,
Pukrop, Tobias,
Dorn, Christoph 
,
Hellerbrand, Claus,
Matos, Carina and
Kreutz, Marina
(2024)
Sex-Dependent T Cell Dysregulation in Mice with Diet-Induced Obesity.
International Journal of Molecular Sciences 25 (15), p. 8234.
Lier, Constantin,
Dejaco, Alexander 
,
Kratzer, Alexander,
Kees, Martin G. 
,
Kees, Frieder and
Dorn, Christoph 
(2024)
Free serum concentrations of antibiotics determined by ultrafiltration: extensive evaluation of experimental variables.
Bioanalysis, pp. 1-10.
Fulltext not available.
Scheuerer, Simon,
Motlova, Lucia,
Schäker-Hübner, Linda,
Sellmer, Andreas,
Feller, Felix,
Ertl, Fabian J.,
Koch, Pierre 
,
Hansen, Finn K.,
Barinka, Cyril and
Mahboobi, Siavosh 
(2024)
Biological and structural investigation of tetrahydro-β-carboline-based selective HDAC6 inhibitors with improved stability.
European Journal of Medicinal Chemistry 276, p. 116676.
Mietzner, Raphael 
,
Barbey, Clara,
Lehr, Heike,
Ziegler, Christian E.,
Peterhoff, David 
,
Wagner, Ralf 
,
Goepferich, Achim 
and
Breunig, Miriam 
(2024)
Prolonged delivery of HIV-1 vaccine nanoparticles from hydrogels.
International Journal of Pharmaceutics 657, p. 124131.
Hosmann, Arthur,
Moser, Miriam M,
van Os, Wisse,
Gramms, Leon,
al Jalali, Valentin,
Sanz Codina, Maria,
Plöchl, Walter,
Lier, Constantin,
Kees, Frieder 
,
Dorn, Christoph 
,
Rössler, Karl,
Reinprecht, Andrea and
Zeitlinger, Markus
(2024)
Linezolid brain penetration in neurointensive care patients.
Journal of Antimicrobial Chemotherapy, dkae025.
Dejaco, Alexander 
,
Dorn, Christoph 
,
Paal, Michael,
Gruber, Michael 
,
Graf, Bernhard M. and
Kees, Martin G. 
(2024)
Determination of glomerular filtration rate “en passant” after high doses of iohexol for computed tomography in intensive care medicine—a proof of concept.
Frontiers in Pharmacology 15.
Haase, André,
Miroschnikov, Natalia,
Klein, Stefan,
Doege, Annika,
Dünker, Nicole,
Van Meenen, Dario,
Junker, Andreas,
Göpferich, Achim 
,
Apaolaza, P. S. and
Busch, Maike Anna
(2024)
New retinoblastoma (RB) drug delivery approaches: anti-tumor effect of atrial natriuretic peptide (ANP)-conjugated hyaluronic-acid-coated gold nanoparticles for intraocular treatment of chemoresistant RB.
Molecular Oncology 18 (4), pp. 832-849.
Fulltext not available.
Wulkersdorfer, Beatrix,
Bergmann, Felix,
Amann, Lisa,
Fochtmann-Frana, Alexandra,
Al Jalali, Valentin,
Kurdina, Elizaveta,
Lackner, Edith,
Wicha, Sebastian G,
Dorn, Christoph 
,
Schäfer, Bruno,
Ihra, Gerald,
Rath, Thomas,
Radtke, Christine and
Zeitlinger, Markus
(2023)
Effect of albumin substitution on pharmacokinetics of piperacillin/tazobactam in patients with severe burn injury admitted to the ICU.
Journal of Antimicrobial Chemotherapy.
Nagl, Martin,
Moennich, Denise,
Rosier, Niklas 
,
Schihada, Hannes,
Sirbu, Alexei,
Konar, Nergis,
Reyes-Resina, Irene,
Navarro, Gemma,
Franco, Rafael,
Kolb, Peter,
Annibale, Paolo and
Pockes, Steffen 
(2023)
Fluorescent Tools for the Imaging of Dopamine D2‐Like Receptors.
ChemBioChem.
Rosier, Niklas 
,
Moennich, Denise,
Nagl, Martin,
Schihada, Hannes,
Sirbu, Alexei,
Konar, Nergis,
Reyes-Resina, Irene,
Navarro, Gemma,
Franco, Rafael,
Kolb, Peter,
Annibale, Paolo and
Pockes, Steffen 
(2023)
Shedding Light on the D1‐Like Receptors: A Fluorescence‐Based Toolbox for Visualization of the D1 and D5 Receptors.
ChemBioChem.
Greppmair, Sebastian,
Brinkmann, Alexander,
Roehr, Anka,
Frey, Otto,
Hagel, Stefan,
Dorn, Christoph 
,
Marsot, Amélie,
El-Haffaf, Ibrahim,
Zoller, Michael,
Saller, Thomas,
Zander, Johannes,
Schatz, Lea Marie,
Scharf, Christina,
Briegel, Josef,
Minichmayr, Iris K.,
Wicha, Sebastian G. and
Liebchen, Uwe
(2023)
Towards model-informed precision dosing of piperacillin: multicenter systematic external evaluation of pharmacokinetic models in critically ill adults with a focus on Bayesian forecasting.
Intensive Care Medicine.
Chen, Zhendong 
,
Taubert, Max,
Chen, Chunli 
,
Dokos, Charalambos,
Fuhr, Uwe,
Weig, Thomas,
Zoller, Michael,
Heck, Suzette,
Dimitriadis, Konstantinos 
,
Terpolilli, Nicole,
Kinast, Christina,
Scharf, Christina,
Lier, Constantin,
Dorn, Christoph and
Liebchen, Uwe
(2023)
Plasma and Cerebrospinal Fluid Population Pharmacokinetics of Vancomycin in Patients with External Ventricular Drain.
Antimicrobial Agents and Chemotherapy.
Fulltext not available.
Wirth, Ulrike,
Erl, Julia,
Azzam, Saphia,
Hoering, Carina,
Skiba, Michael,
Singh, Ritu,
Hochmuth, Kathrin,
Keller, Max,
Wegener, Joachim 
and
König, Burkhard 
(2023)
Monitoring the Reversibility of GPCR Signaling by Combining Photochromic Ligands with Label-free Impedance Analysis.
Angewandte Chemie International Edition, e202215547.
Kuzo, Nazar,
Haen, Ekkehard,
Ho, Dominic M.,
Takeuchi, Hiroyoshi,
Piras, Marianna,
Eap, Chin-Bin,
de Filippis, Renato,
Homan, Philipp,
Kane, John M.,
Roy, Marc-André,
Paulzen, Michael and
Schoretsanitis, Georgios
(2023)
Clozapine once- versus multiple-daily dosing: a two-center cross-sectional study, systematic review and meta-analysis.
European Archives of Psychiatry and Clinical Neuroscience 273 (7), pp. 1567-1578.
Fulltext not available.
Margraff, Teresa,
Schoretsanitis, Georgios 
,
Neuner, Irene,
Haen, Ekkehard,
Gaebler, Arnim Johannes 
and
Paulzen, Michael
(2023)
Discovering interactions in augmentation strategies: Impact of duloxetine on the metabolism of aripiprazole.
Basic & Clinical Pharmacology & Toxicology 133 (1), pp. 73-81.
Fulltext not available.
Mönnich, Denise,
Nagl, Martin,
Forster, Lisa,
Rosier, Niklas,
Igel, Patrick and
Pockes, Steffen
(2023)
Discovery of a Tritiated Radioligand with High Affinity and Selectivity for the Histamine H3 Receptor.
ACS Medicinal Chemistry Letters 14 (11), pp. 1589-1595.
Fulltext not available.
Szczepańska, Katarzyna,
Karcz, Tadeusz,
Dichiara, Maria,
Mogilski, Szczepan,
Kalinowska-Tłuścik, Justyna,
Pilarski, Bogusław,
Leniak, Arkadiusz,
Pietruś, Wojciech 
,
Podlewska, Sabina 
,
Popiołek-Barczyk, Katarzyna,
Humphrys, Laura J. 
,
Ruiz-Cantero, M. Carmen,
Reiner-Link, David 
,
Leitzbach, Luisa,
Łażewska, Dorota,
Pockes, Steffen 
,
Górka, Michał,
Zmysłowski, Adam,
Calmels, Thierry,
Cobos, Enrique J.,
Marrazzo, Agostino,
Stark, Holger,
Bojarski, Andrzej J.,
Amata, Emanuele and
Kieć-Kononowicz, Katarzyna
(2023)
Dual Piperidine-Based Histamine H3 and Sigma-1 Receptor Ligands in the Treatment of Nociceptive and Neuropathic Pain.
Journal of Medicinal Chemistry 66 (14), pp. 9658-9683.
Fulltext not available.
Jacob, Hannes,
Braekow, Pauline,
Hofmann, Britt,
Kirchhefer, Uwe,
Forster, Lisa,
Mönnich, Denise,
Humphrys, Laura J.,
Pockes, Steffen,
Neumann, Joachim and
Gergs, Ulrich
(2023)
Ergometrine stimulates histamine H2 receptors in the isolated human atrium.
Naunyn-Schmiedeberg's Archives of Pharmacology 396 (12), pp. 3809-3822.
Fulltext not available.
Kolev, Iliyan,
Dimova, Tanya,
Iliev, Ivan,
Rogozherov, Marin and
Bodensteiner, Michael
(2023)
Further findings concerning 2,6-diiodo-3,4,5-trimethoxybenzoic acid (Part II).
Journal of Molecular Structure 1294, p. 136388.
Fulltext not available.
Zimmer, Oliver,
Walter, Melanie,
Remmert, Marius,
Maier, Olga,
Witzgall, Ralph and
Goepferich, Achim
(2023)
Impact of interferon-γ on the target cell tropism of nanoparticles.
Journal of Controlled Release 362, pp. 325-341.
Fulltext not available.
Gaebler, Arnim Johannes 
,
Haen, Ekkehard,
Omar, Nagia Ben,
Endres, Katharina,
Hiemke, Christoph,
Schoretsanitis, Georgios and
Paulzen, Michael
(2023)
Lower sertraline plasma concentration in patients co‐medicated with clozapine—Implications for pharmacological augmentation strategies in schizophrenia.
Pharmacology Research & Perspectives 11 (2).
Fulltext not available.
Barda, Christina,
Tzoumaka, Alexia,
Grafakou, Maria-Eleni,
Kalpoutzakis, Eleutherios,
Heilmann, Joerg and
Skaltsa, Helen
(2023)
Phytochemical Characterization of Phitosia crocifolia, a Monotypic Representative of Greek Flora.
Planta Medica 89 (03), pp. 324-332.
Fulltext not available.
Plut, Eva 
,
Calderón, Jacqueline C.,
Stanojlović, Vesna,
Gattor, Albert O.,
Höring, Carina,
Humphrys, Laura J.,
Konieczny, Adam,
Kerres, Sabine,
Schubert, Mario 
,
Keller, Max,
Cabrele, Chiara,
Clark, Timothy and
Reiser, Oliver
(2023)
Stereochemistry-Driven Interactions of α,γ-Peptide Ligands with the Neuropeptide Y Y4-Receptor.
Journal of Medicinal Chemistry 66 (14), pp. 9642-9657.
Fulltext not available.
Sanz-Codina, Maria,
Wicha, Sebastian G,
Wulkersdorfer, Beatrix,
Al Jalali, Valentin,
Van Os, Wisse,
Vossen, Matthias G,
Bauer, Martin,
Lackner, Edith,
Dorn, Christoph 
and
Zeitlinger, Markus
(2022)
Comparison of ultrafiltration and microdialysis for ceftriaxone protein-binding determination.
Journal of Antimicrobial Chemotherapy.
Fulltext not available.
Schindler, Lisa,
Moosbauer, Jutta,
Schmidt, Daniel 
,
Spruss, Thilo,
Grätz, Lukas,
Lüdeke, Steffen,
Hofheinz, Frank,
Meister, Sebastian,
Echtenacher, Bernd,
Bernhardt, Günther,
Pietzsch, Jens 
,
Hellwig, Dirk 
and
Keller, Max
(2022)
Development of a Neurotensin-Derived 68Ga-Labeled PET Ligand with High In Vivo Stability for Imaging of NTS1 Receptor-Expressing Tumors.
Cancers 14 (19), p. 4922.
Bohley, Marilena,
Dillinger, Andrea E.,
Schweda, Frank,
Ohlmann, Andreas,
Braunger, Barbara M.,
Tamm, Ernst R. and
Goepferich, Achim 
(2022)
A single intravenous injection of cyclosporin A–loaded lipid nanocapsules prevents retinopathy of prematurity.
Science Advances 8 (38).
Heinl, Elena-Sofia,
Lorenz, Sebastian,
Schmidt, Barbara 
,
Laqtom, Nouf Nasser M.,
Mazzulli, Joseph R.,
Francelle, Laetitia 
,
Yu, Timothy W.,
Greenberg, Benjamin 
,
Storch, Stephan,
Tegtmeier, Ines,
Othmen, Helga,
Maurer, Katja,
Steinfurth, Malin,
Witzgall, Ralph,
Milenkovic, Vladimir M.,
Wetzel, Christian H. 
and
Reichold, Markus
(2022)
CLN7/MFSD8 may be an important factor for SARS-CoV-2 cell entry.
iScience 25 (10), p. 105082.
Dorn, Christoph 
,
Petroff, David,
Kratzer, Alexander,
Kees, Frieder,
Kloft, Charlotte,
Zeitlinger, Markus 
,
Wrigge, Hermann and
Simon, Philipp
(2022)
Tigecycline Soft Tissue Penetration in Obese and Non-obese Surgical Patients Determined by Using In Vivo Microdialysis.
European Journal of Drug Metabolism and Pharmacokinetics 47, pp. 749-755.
Meurer, Florian 
,
Dolomanov, Oleg V.,
Hennig, Christoph 
,
Peyerimhoff, Norbert 
,
Kleemiss, Florian 
,
Puschmann, Horst and
Bodensteiner, Michael 
(2022)
Refinement of anomalous dispersion correction parameters in single-crystal structure determinations.
IUCrJ / International Union of Crystallography 9 (5), pp. 604-609.
Willkomm, Sarah 
,
Jakob, Leonhard,
Kramm, Kevin,
Graus, Veronika,
Neumeier, Julia,
Meister, Gunter and
Grohmann, Dina 
(2022)
Single-molecule FRET uncovers hidden conformations and dynamics of human Argonaute 2.
Nature Communications 13, art.no.3825.
Bresinsky, Merlin,
Strasser, Jessica M.,
Hubmann, Alexander,
Vallaster, Bernadette,
McCue, William M.,
Fuller, Jessica,
Singh, Gurpreet,
Nelson, Kathryn M.,
Cuellar, Matthew E.,
Finzel, Barry C.,
Ashe, Karen H.,
Walters, Michael A. and
Pockes, Steffen 
(2022)
Characterization of caspase‐2 inhibitors based on specific sites of caspase‐2‐mediated proteolysis.
Archiv der Pharmazie 355 (9), p. 2200095.
Jorda, Anselm 
,
Wulkersdorfer, Beatrix,
Schörgenhofer, Christian,
Matzneller, Peter 
,
Al Jalali, Valentin,
Bauer, Martin 
,
Wölf-Duchek, Michael,
Lackner, Edith,
Dorn, Christoph,
Jilma, Bernd 
and
Zeitlinger, Markus 
(2022)
Influence of tedizolid on the cytokine response to the endotoxin challenge in healthy volunteers: a cross-over trial.
Journal of Antimicrobial Chemotherapy.
Fulltext not available.
Ousingsawat, Jiraporn 
,
Centeio, Raquel,
Cabrita, Inês 
,
Talbi, Khaoula,
Zimmer, Oliver 
,
Graf, Moritz,
Göpferich, Achim 
,
Schreiber, Rainer 
and
Kunzelmann, Karl 
(2022)
Airway Delivery of Hydrogel-Encapsulated Niclosamide for the Treatment of Inflammatory Airway Disease.
International Journal of Molecular Sciences 23 (3), p. 1085.
Rösch, Gundula,
Muschter, Dominique,
Taheri, Shahed 
,
El Bagdadi, Karima,
Dorn, Christoph,
Meurer, Andrea,
Zaucke, Frank,
Schilling, Arndt F.,
Grässel, Susanne,
Straub, Rainer H. and
Jenei-Lanzl, Zsuzsa 
(2022)
β2-Adrenoceptor Deficiency Results in Increased Calcified Cartilage Thickness and Subchondral Bone Remodeling in Murine Experimental Osteoarthritis.
Frontiers in Immunology 12.
Tahk, Maris-Johanna 
,
Torp, Jane 
,
Ali, Mohammed A. S. 
,
Fishman, Dmytro,
Parts, Leopold 
,
Grätz, Lukas 
,
Müller, Christoph 
,
Keller, Max 
,
Veiksina, Santa 
,
Laasfeld, Tõnis 
and
Rinken, Ago 
(2022)
Live-cell microscopy or fluorescence anisotropy with budded baculoviruses—which way to go with measuring ligand binding to M 4 muscarinic receptors?
Open Biology 12 (6).
Fulltext not available.
Barda, Christina,
Anastasiou, Konstantina,
Tzara, Ariadni,
Grafakou, Maria-Eleni,
Kalpoutzakis, Eleftherios,
Heilmann, Joerg,
Rallis, Michael,
Kourounakis, Angeliki P. and
Skaltsa, Helen
(2022)
A Bio-Guided Screening for Antioxidant, Anti-Inflammatory and Hypolipidemic Potential Supported by Non-Targeted Metabolomic Analysis of Crepis spp.
Molecules 27 (19), p. 6173.
Fulltext not available.
Andreev, Stanislav,
Pantsar, Tatu,
Tesch, Roberta,
Kahlke, Niclas,
El-Gokha, Ahmed,
Ansideri, Francesco,
Grätz, Lukas,
Romasco, Jenny,
Sita, Giulia,
Geibel, Christian 
,
Lämmerhofer, Michael,
Tarozzi, Andrea,
Knapp, Stefan 
,
Laufer, Stefan A. and
Koch, Pierre 
(2022)
Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors.
Journal of Medicinal Chemistry 65 (2), pp. 1283-1301.
Fulltext not available.
Mandigma, Mark John P. 
,
Žurauskas, Jonas,
MacGregor, Callum I.,
Edwards, Lee J. 
,
Shahin, Ahmed 
,
d'Heureuse, Ludwig,
Yip, Philip,
Birch, David J. S. 
,
Gruber, Thomas,
Heilmann, Jörg,
John, Matthew P. and
Barham, Joshua P. 
(2022)
An organophotocatalytic late-stage N–CH3oxidation of trialkylamines toN-formamides with O2in continuous flow.
Chemical Science 13 (7), pp. 1912-1924.
Fulltext not available.
Katsouri, Ilektra Petrina,
Vandervelpen, Ebert Vinciane G.,
Gattor, Albert Owusu,
Engelbeen, Sarah,
El Sayed, Abdulrahman,
Seitaj, Klejdia,
Becerra, Eduardo Daniel Morales and
Vanderheyden, Patrick M.L.
(2022)
Complex FFA1 receptor (in)dependent modulation of calcium signaling by free fatty acids.
Biochemical Pharmacology 202, p. 115150.
Fulltext not available.
Schoretsanitis, Georgios,
Haen, Ekkehard,
Piacentino, Daria,
Conca, Andreas,
Endres, Katharina,
Hiemke, Christoph,
Gründer, Gerhard and
Paulzen, Michael
(2022)
Effects of body weight, smoking status, and sex on plasma concentrations of once-monthly paliperidone palmitate.
Expert Review of Clinical Pharmacology 15 (2), pp. 243-249.
Fulltext not available.
Beyer, Mandy,
Henninger, Sven J.,
Haehnel, Patricia S.,
Mustafa, Al-Hassan M. 
,
Gurdal, Ece 
,
Schubert, Bastian,
Christmann, Markus,
Sellmer, Andreas 
,
Mahboobi, Siavosh,
Drube, Sebastian,
Sippl, Wolfgang,
Kindler, Thomas and
Krämer, Oliver H.
(2022)
Identification of a highly efficient dual type I/II FMS-like tyrosine kinase inhibitor that disrupts the growth of leukemic cells.
Cell Chemical Biology 29 (3), 398-411.e4.
Fulltext not available.
Schihada, Hannes,
Klompstra, Thomas M. 
,
Humphrys, Laura J. 
,
Cervenka, Igor,
Dadvar, Shamim 
,
Kolb, Peter 
,
Ruas, Jorge L. 
and
Schulte, Gunnar 
(2022)
Isoforms of GPR35 have distinct extracellular N-termini that allosterically modify receptor-transducer coupling and mediate intracellular pathway bias.
Journal of Biological Chemistry 298 (9), p. 102328.
Fulltext not available.
Peterhoff, David 
,
Thalhauser, Stefanie,
Neckermann, Patrick 
,
Barbey, Clara,
Straub, Kristina,
Nazet, Julian,
Merkl, Rainer,
Längst, Gernot,
Breunig, Miriam 
and
Wagner, Ralf
(2022)
Multivalent display of engineered HIV-1 envelope trimers on silica nanoparticles for targeting and in vitro activation of germline VRC01 B cells.
European Journal of Pharmaceutics and Biopharmaceutics 181, pp. 88-101.
Fulltext not available.
Schindler, Lisa,
Wohlfahrt, Katrin,
Gluhacevic von Krüchten, Lara,
Prante, Olaf,
Keller, Max and
Maschauer, Simone
(2022)
Neurotensin analogs by fluoroglycosylation at Nω-carbamoylated arginines for PET imaging of NTS1-positive tumors.
Scientific Reports 12 (1).
Fulltext not available.
Greinwald, Anja,
Hartmann, Martin,
Heilmann, Jörg,
Heinrich, Michael,
Luick, Rainer and
Reif, Albert
(2022)
Soil and Vegetation Drive Sesquiterpene Lactone Content and Profile in Arnica montana L. Flower Heads From Apuseni-Mountains, Romania.
Frontiers in Plant Science 13.
Fulltext not available.
Szczepańska, Katarzyna,
Podlewska, Sabina,
Dichiara, Maria,
Gentile, Davide,
Patamia, Vincenzo,
Rosier, Niklas,
Mönnich, Denise,
Ruiz Cantero, Ma Carmen,
Karcz, Tadeusz,
Łażewska, Dorota,
Siwek, Agata,
Pockes, Steffen,
Cobos, Enrique J.,
Marrazzo, Agostino,
Stark, Holger,
Rescifina, Antonio,
Bojarski, Andrzej J.,
Amata, Emanuele and
Kieć-Kononowicz, Katarzyna
(2022)
Structural and Molecular Insight into Piperazine and Piperidine Derivatives as Histamine H3 and Sigma-1 Receptor Antagonists with Promising Antinociceptive Properties.
ACS Chemical Neuroscience 13 (1), pp. 1-15.
Fulltext not available.
Müller, Christoph,
Gleixner, Jakob 
,
Tahk, Maris-Johanna 
,
Kopanchuk, Sergei 
,
Laasfeld, Tõnis,
Weinhart, Michael,
Schollmeyer, Dieter,
Betschart, Martin U.,
Lüdeke, Steffen,
Koch, Pierre,
Rinken, Ago 
and
Keller, Max
(2022)
Structure-Based Design of High-Affinity Fluorescent Probes for the Neuropeptide Y Y1 Receptor.
Journal of Medicinal Chemistry 65 (6), pp. 4832-4853.
Fulltext not available.
Rösch, G.,
El Bagdadi, K.,
Muschter, D.,
Taheri, S. 
,
Dorn, C.,
Meurer, A.,
Straub, R.H.,
Zaucke, F. 
,
Schilling, A.F.,
Grässel, S. and
Jenei-Lanzl, Z. 
(2022)
Sympathectomy aggravates subchondral bone changes during osteoarthritis progression in mice without affecting cartilage degeneration or synovial inflammation.
Osteoarthritis and Cartilage 30 (3), pp. 461-474.
Fulltext not available.
Mietzner, Raphael 
,
Pawlak, Ramona 
,
Tamm, Ernst R.,
Goepferich, Achim 
,
Fuchshofer, Rudolf and
Breunig, Miriam 
(2021)
Angiopoietin-1 Mimetic Nanoparticles for Restoring the Function of Endothelial Cells as Potential Therapeutic for Glaucoma.
Pharmaceuticals 15 (1), p. 18.
Busse, David,
Simon, Philipp,
Schmitt, Lisa,
Petroff, David,
Dorn, Christoph 
,
Dietrich, Arne,
Zeitlinger, Markus,
Huisinga, Wilhelm,
Michelet, Robin,
Wrigge, Hermann and
Kloft, Charlotte
(2021)
Comparative Plasma and Interstitial Tissue Fluid Pharmacokinetics of Meropenem Demonstrate the Need for Increasing Dose and Infusion Duration in Obese and Non-obese Patients.
Clinical Pharmacokinetics.
Dorn, Christoph 
(2021)
3.3. Informationen über Arzneimittel.
In:
Sax, Michael, (ed.)
Pharmazie für die Praxis : Lehrbuch für Pharmazeuten im Praktikum : Handbuch für die Apotheke.
Deutscher Apotheker Verlag, Stuttgart, pp. 152-173.
ISBN 978-3-7692-7010-5.
Fulltext not available.
Rösch, Gundula,
El Bagdadi, Karima,
Muschter, Dominique 
,
Taheri, Shahed,
Dorn, Christoph 
,
Meurer, Andrea,
Straub, Rainer H. 
,
Zaucke, Frank 
,
Schilling, Arndt F.,
Grässel, Susanne 
and
Jenei-Lanzl, Zsuzsa
(2021)
Sympathectomy aggravates subchondral bone changes during osteoarthritis progression in mice without affecting cartilage degeneration or synovial inflammation.
Osteoarthritis and Cartilage 30 (3), pp. 461-474.
Fulltext not available.
Wachholz, Vanessa,
Mustafa, Al-Hassan M.,
Zeyn, Yanira,
Henninger, Sven J.,
Beyer, Mandy,
Dzulko, Melanie,
Piée-Staffa, Andrea,
Brachetti, Christina,
Haehnel, Patricia S.,
Sellmer, Andreas,
Mahboobi, Siavosh,
Kindler, Thomas,
Brenner, Walburgis,
Nikolova, Teodora and
Krämer, Oliver H.
(2021)
Inhibitors of class I HDACs and of FLT3 combine synergistically against leukemia cells with mutant FLT3.
Archives of Toxicology 96 (1), pp. 177-193.
Busse, David,
Borghardt, Jens Markus,
Petroff, David,
Pevzner, Alice,
Dorn, Christoph 
,
El‐Najjar, Nahed,
Huisinga, Wilhelm,
Wrigge, Hermann,
Simon, Philipp and
Kloft, Charlotte
(2021)
EVALUATING PREDICTION METHODS FOR GLOMERULAR FILTRATION TO OPTIMISE DRUG DOSES IN OBESE AND NON‐OBESE PATIENTS.
British Journal of Clinical Pharmacology.
Fulltext not available.
Höring, Carina 
,
Conrad, Marcus,
Söldner, Christian A. 
,
Wang, Jinan 
,
Sticht, Heinrich 
,
Strasser, Andrea and
Miao, Yinglong
(2021)
Specific Engineered G Protein Coupling to Histamine Receptors Revealed from Cellular Assay Experiments and Accelerated Molecular Dynamics Simulations.
International Journal of Molecular Sciences 22 (18), pp. 1-21.
Busse, David 
,
Simon, Philipp 
,
Petroff, David,
Dorn, Christoph,
Schmitt, Lisa,
Bindellini, Davide,
Kratzer, Alexander,
Dietrich, Arne,
Zeitlinger, Markus,
Huisinga, Wilhelm 
,
Michelet, Robin 
,
Wrigge, Hermann and
Kloft, Charlotte
(2021)
Similar Piperacillin/Tazobactam Target Attainment in Obese versus Nonobese Patients despite Differences in Interstitial Tissue Fluid Pharmacokinetics.
Pharmaceutics 13 (9), p. 1380.
Breunig, Miriam,
Sonntag, Tobias,
Froemel, Franziska,
Stamer, W. Daniel,
Ohlmann, Andreas and
Fuchshofer, Rudolf 
(2021)
Distribution of Gold Nanoparticles in the Anterior Chamber of the Eye after Intracameral Injection for Glaucoma Therapy.
Pharmaceutics 2021 (13), p. 901.
(Submitted)
Peterhoff, David 
,
Thalhauser, Stefanie,
Sobczak, Jan M.,
Mohsen, Mona O.,
Voigt, Christoph,
Seifert, Nicole 
,
Neckermann, Patrick,
Hauser, Alexandra 
,
Ding, Song,
Sattentau, Quentin,
Bachmann, Martin F. 
,
Breunig, Miriam 
and
Wagner, Ralf 
(2021)
Augmenting the Immune Response against a Stabilized HIV-1 Clade C Envelope Trimer by Silica Nanoparticle Delivery.
Vaccines 9 (642), pp. 1-24.
Schießer, Selina,
Hitzenbichler, Florian,
Kees, Martin Georg,
Kratzer, Alexander,
Lubnow, Matthias 
,
Salzberger, Bernd 
,
Kees, Frieder 
and
Dorn, Christoph 
(2021)
Measurement of Free Plasma Concentrations of Beta-Lactam Antibiotics.
Therapeutic Drug Monitoring 43 (2), pp. 264-270.
Fulltext not available.
Hoffmeister, Helen,
Fuchs, Andreas 
,
Komives, Elizabeth,
Groebner‐Ferreira, Regina,
Strobl, Laura,
Nazet, Julian,
Heizinger, Leonhard,
Merkl, Rainer,
Dove, Stefan and
Längst, Gernot
(2021)
Sequence and functional differences in the ATPase domains of CHD3 and SNF2H promise potential for selective regulability and drugability.
The FEBS Journal 288, pp. 4000-4023.
Rosier, Niklas,
Grätz, Lukas,
Schihada, Hannes 
,
Möller, Jan,
Işbilir, Ali 
,
Humphrys, Laura J. 
,
Nagl, Martin,
Seibel, Ulla,
Lohse, Martin J. 
and
Pockes, Steffen 
(2021)
A Versatile Sub-Nanomolar Fluorescent Ligand Enables NanoBRET Binding Studies and Single-Molecule Microscopy at the Histamine H3 Receptor.
Journal of Medicinal Chemistry 64 (15), pp. 11695-11708.
Fulltext not available.
Tropmann, Katharina,
Bresinsky, Merlin,
Forster, Lisa,
Mönnich, Denise,
Buschauer, Armin 
,
Wittmann, Hans-Joachim,
Hübner, Harald,
Gmeiner, Peter,
Pockes, Steffen 
and
Strasser, Andrea 
(2021)
Abolishing Dopamine D2long/D3 Receptor Affinity of Subtype-Selective Carbamoylguanidine-Type Histamine H2 Receptor Agonists.
Journal of Medicinal Chemistry 64 (12), pp. 8684-8709.
Fulltext not available.
Grätz, Lukas,
Laasfeld, Tõnis,
Allikalt, Anni 
,
Gruber, Corinna G.,
Pegoli, Andrea,
Tahk, Maris-Johanna,
Tsernant, Mari-Liis,
Keller, Max and
Rinken, Ago
(2021)
BRET- and fluorescence anisotropy-based assays for real-time monitoring of ligand binding to M2 muscarinic acetylcholine receptors.
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1868 (3), p. 118930.
Fulltext not available.
Kuzin, Maxim 
,
Haen, Ekkehard,
Hiemke, Christoph 
,
Bochon, Benjamin,
Bochon, Karolina,
Gründer, Gerhard,
Paulzen, Michael and
Schoretsanitis, Georgios 
(2021)
Body mass index as a determinant of clozapine plasma concentrations: A pharmacokinetic-based hypothesis.
Journal of Psychopharmacology 35 (3), pp. 273-278.
Fulltext not available.
Gergs, Ulrich,
Büxel, Maren L.,
Bresinsky, Merlin,
Kirchhefer, Uwe,
Fehse, Charlotte,
Höring, Carina,
Hofmann, Britt,
Marušáková, Margaréta,
Čináková, Aneta,
Schwarz, Rebecca,
Pockes, Steffen 
and
Neumann, Joachim
(2021)
Cardiac Effects of Novel Histamine H2 Receptor Agonists.
Journal of Pharmacology and Experimental Therapeutics 379 (3), pp. 223-234.
Fulltext not available.
Stoelzle-Feix, Sonja,
Juhasz, Krisztina,
Skiba, Michael,
Wegener, Joachim,
Knox, Ronald,
Lemme, Marta,
Thomas, Ulrich,
Engelstaedter, Max,
Dragicevic, Elena,
George, Michael and
Fertig, Niels
(2021)
Cell monitoring using multi-frequency impedance recordings for label-free and time-resolved cell response analysis.
Journal of Pharmacological and Toxicological Methods 111, p. 106969.
Fulltext not available.
Schoretsanitis, Georgios,
Haen, Ekkehard,
Piacentino, Daria,
Conca, Andreas,
Endres, Katharina,
Hiemke, Christoph,
Gründer, Gerhard and
Paulzen, Michael
(2021)
Clinical response in patients treated with once-monthly paliperidone palmitate: analysis of a therapeutic drug monitoring (TDM) database.
European Archives of Psychiatry and Clinical Neuroscience 271 (8), pp. 1437-1443.
Fulltext not available.
Reynders, Martin,
Chaikuad, Apirat,
Berger, Benedict‐Tilman,
Bauer, Katharina,
Koch, Pierre 
,
Laufer, Stefan,
Knapp, Stefan and
Trauner, Dirk
(2021)
Controlling the Covalent Reactivity of a Kinase Inhibitor with Light.
Angewandte Chemie International Edition 60 (37), pp. 20178-20183.
Fulltext not available.
Wörle, Elisabeth,
Jakob, Leonhard,
Schmidbauer, Andreas,
Zinner, Gabriel and
Grohmann, Dina
(2021)
Decoupling the bridge helix of Cas12a results in a reduced trimming activity, increased mismatch sensitivity and impaired conformational transitions.
Nucleic Acids Research 49 (9), pp. 5278-5293.
Fulltext not available.
Weinhart, Corinna. G.,
Wifling, David,
Schmidt, Maximilian. F.,
Neu, Eduard,
Höring, Carina,
Clark, Timothy,
Gmeiner, Peter and
Keller, Max
(2021)
Dibenzodiazepinone-type muscarinic receptor antagonists conjugated to basic peptides: Impact of the linker moiety and unnatural amino acids on M2R selectivity.
European Journal of Medicinal Chemistry 213, p. 113159.
Fulltext not available.
Gaebler, Arnim Johannes 
,
Schoretsanitis, Georgios,
Ben Omar, Nagia,
Haen, Ekkehard,
Endres, Katharina,
Hiemke, Christoph and
Paulzen, Michael
(2021)
Metamizole but not ibuprofen reduces the plasma concentration of sertraline: Implications for the concurrent treatment of pain and depression/anxiety disorders.
British Journal of Clinical Pharmacology 87 (3), pp. 1111-1119.
Konieczny, Adam,
Conrad, Marcus,
Ertl, Fabian J.,
Gleixner, Jakob,
Gattor, Albert O.,
Grätz, Lukas,
Schmidt, Maximilian F.,
Neu, Eduard,
Horn, Anselm H. C.,
Wifling, David,
Gmeiner, Peter,
Clark, Timothy,
Sticht, Heinrich and
Keller, Max
(2021)
N-Terminus to Arginine Side-Chain Cyclization of Linear Peptidic Neuropeptide Y Y4 Receptor Ligands Results in Picomolar Binding Constants.
Journal of Medicinal Chemistry 64 (22), pp. 16746-16769.
Fulltext not available.
Dorn, Christoph 
,
Petroff, David,
Stoelzel, Melanie,
Kees, Martin G. 
,
Kratzer, Alexander,
Dietrich, Arne,
Kloft, Charlotte,
Zeitlinger, Markus,
Kees, Frieder 
,
Wrigge, Hermann and
Simon, Philipp
(2021)
Perioperative administration of cefazolin and metronidazole in obese and non-obese patients: a pharmacokinetic study in plasma and interstitial fluid.
Journal of Antimicrobial Chemotherapy.
Fulltext not available.
Schoretsanitis, Georgios,
Haen, Ekkehard,
Piacentino, Daria,
Conca, Andreas,
Endres, Katharina,
Carpi, Fabio,
Hiemke, Christoph,
Gründer, Gerhard and
Paulzen, Michael
(2021)
Pharmacokinetic Correlates of Once-Monthly Paliperidone Palmitate-Related Adverse Drug Reactions.
Clinical Pharmacokinetics 60 (12), pp. 1583-1589.
Fulltext not available.
Biselli, Sabrina,
Bresinsky, Merlin,
Tropmann, Katharina,
Forster, Lisa 
,
Honisch, Claudia 
,
Buschauer, Armin,
Bernhardt, Günther and
Pockes, Steffen 
(2021)
Pharmacological characterization of a new series of carbamoylguanidines reveals potent agonism at the H2R and D3R.
European Journal of Medicinal Chemistry 214, p. 113190.
Fulltext not available.
Al Jalali, V. 
,
Wölfl-Duchek, M.,
Taubert, M. 
,
Matzneller, P. 
,
Lackner, E.,
Dorn, Christoph 
,
Kratzer, A.,
Wulkersdorfer, B.,
Österreicher, Z and
Zeitlinger, Markus
(2021)
Plasma and soft tissue pharmacokinetics of ceftolozane/tazobactam in healthy volunteers after single and multiple intravenous infusion: a microdialysis study.
Journal of Antimicrobial Chemotherapy.
Fulltext not available.
Grafakou, Maria-Eleni,
Barda, Christina,
Pintać, Diandra,
Lesjak, Marija,
Heilmann, Jörg and
Skaltsa, Helen
(2021)
Prenylated Acylphloroglucinols from Hypericum jovis with Anti-inflammatory Potential.
Planta Medica 87 (14), pp. 1184-1191.
Fulltext not available.
Aldag, Pierre,
Welzel, Fabian,
Jakob, Leonhard,
Schmidbauer, Andreas,
Rutkauskas, Marius,
Fettes, Fergus,
Grohmann, Dina and
Seidel, Ralf 
(2021)
Probing the stability of the SpCas9–DNA complex after cleavage.
Nucleic Acids Research 49 (21), pp. 12411-12421.
Fulltext not available.
Wulkersdorfer, Beatrix,
Wicha, Sebastian G.,
Kurdina, Elizaveta,
Carrion Carrera, Stephan F.,
Matzneller, Peter,
Al Jalali, Valentin,
Vossen, Matthias G.,
Riesenhuber, Sonja,
Lackner, Edith,
Dorn, Christoph 
and
Zeitlinger, Markus
(2021)
Protein binding of clindamycin in vivo by means of intravascular microdialysis in healthy volunteers.
Journal of Antimicrobial Chemotherapy.
Fulltext not available.
Daskalaki, Artemis,
Grafakou, Maria-Eleni 
,
Barda, Christina,
Kypriotakis, Zacharias,
Heilmann, Jörg and
Skaltsa, Helen
(2021)
Secondary metabolites from Hypericum trichocaulon Boiss. & Heldr., growing wild in the island of crete.
Biochemical Systematics and Ecology 97, p. 104294.
Fulltext not available.
Szczepańska, Katarzyna 
,
Pockes, Steffen 
,
Podlewska, Sabina,
Höring, Carina,
Mika, Kamil,
Latacz, Gniewomir,
Bednarski, Marek,
Siwek, Agata 
,
Karcz, Tadeusz,
Nagl, Martin,
Bresinsky, Merlin,
Mönnich, Denise,
Seibel, Ulla,
Kuder, Kamil J. 
,
Kotańska, Magdalena,
Stark, Holger,
Elz, Sigurd and
Kieć-Kononowicz, Katarzyna
(2021)
Structural modifications in the distal, regulatory region of histamine H3 receptor antagonists leading to the identification of a potent anti-obesity agent.
European Journal of Medicinal Chemistry 213, p. 113041.
Fulltext not available.
Eap, C. B. 
,
Gründer, G. 
,
Baumann, P. 
,
Ansermot, N.,
Conca, A.,
Corruble, E.,
Crettol, S.,
Dahl, M. L.,
de Leon, J. 
,
Greiner, C.,
Howes, O.,
Kim, E.,
Lanzenberger, R.,
Meyer, J. H.,
Moessner, R.,
Mulder, H.,
Müller, D. J.,
Reis, M.,
Riederer, P.,
Ruhe, H. G.,
Spigset, O.,
Spina, E.,
Stegman, B.,
Steimer, W.,
Stingl, J. 
,
Suzen, S.,
Uchida, H.,
Unterecker, S.,
Vandenberghe, F. 
and
Hiemke, C. 
(2021)
Tools for optimising pharmacotherapy in psychiatry (therapeutic drug monitoring, molecular brain imaging and pharmacogenetic tests): focus on antidepressants.
The World Journal of Biological Psychiatry 22 (8), pp. 561-628.
Fulltext not available.
Höring, Carina 
,
Seibel, Ulla 
,
Tropmann, Katharina,
Grätz, Lukas 
,
Mönnich, Denise 
,
Pitzl, Sebastian,
Bernhardt, Günther 
,
Pockes, Steffen 
and
Strasser, Andrea
(2020)
A Dynamic, Split-Luciferase-Based Mini-G Protein Sensor to Functionally Characterize Ligands at All Four Histamine Receptor Subtypes.
International Journal of Molecular Sciences 21 (22), p. 8440.
Simeth, Nadja Anita 
,
Kinateder, Thomas,
Rajendran, Chitra,
Nazet, Julian,
Merkl, Rainer 
,
Sterner, Reinhard 
,
König, Burkhard 
and
Kneuttinger, Andrea C. 
(2020)
Towards Photochromic Azobenzene‐Based Inhibitors for Tryptophan Synthase.
Chemistry—A European Journal 27, pp. 2439-2451.
Grätz, Lukas,
Tropmann, Katharina,
Bresinsky, Merlin,
Müller, Christoph,
Bernhardt, Günther 
and
Pockes, Steffen
(2020)
NanoBRET binding assay for histamine H2 receptor ligands using live recombinant HEK293T cells.
Scientific Reports 10, p. 13288.
Mietzner, Raphael 
,
Kade, Christian,
Froemel, Franziska,
Pauly, Diana,
Stamer, W. Daniel,
Ohlmann, Andreas,
Wegener, Joachim,
Fuchshofer, Rudolf and
Breunig, Miriam 
(2020)
Fasudil Loaded PLGA Microspheres as Potential Intravitreal Depot Formulation for Glaucoma Therapy.
Pharmaceutics 12 (8), p. 706.
Bartole, Edith,
Grätz, Lukas,
Littmann, Timo,
Wifling, David 
,
Seibel, Ulla,
Buschauer, Armin 
and
Bernhardt, Günther
(2020)
UR-DEBa242: A Py-5-Labeled Fluorescent Multipurpose Probe for Investigations on the Histamine H3 and H4 Receptors.
Journal of Medicinal Chemistry 63 (10), pp. 5297-5311.
Fulltext not available.
Maslanka Figueroa, Sara 
,
Fleischmann, Daniel,
Beck, Sebastian,
Tauber, Philipp,
Witzgall, Ralph,
Schweda, Frank and
Goepferich, Achim
(2020)
Nanoparticles Mimicking Viral Cell Recognition Strategies Are Superior Transporters into Mesangial Cells.
Advanced Science 7 (11), p. 1903204.
Dorn, Christoph 
,
Schießer, Selina,
Wulkersdorfer, Beatrix,
Hitzenbichler, Florian,
Kees, Martin G. 
and
Zeitlinger, Markus
(2020)
Determination of free clindamycin, flucloxacillin or tedizolid in plasma: Keep attention to physiological conditions when using ultrafiltration.
Biomedical Chromatography 34, e4820.
Koehler, Katrin,
Hmida, Dorra,
Schlossmann, Jens,
Landgraf, Dana,
Reisch, Nicole,
Schuelke, Markus and
Huebner, Angela
(2020)
Homozygous mutation in murine retrovirus integration site 1 gene associated with a non‐syndromic form of isolated familial achalasia.
Neurogastroenterology & Motility 32 (12).
Fulltext not available.
Sellmer, Andreas,
Pilsl, Bernadette,
Beyer, Mandy,
Pongratz, Herwig,
Wirth, Lukas,
Elz, Sigurd,
Dove, Stefan,
Henninger, Sven Julian,
Spiekermann, Karsten,
Polzer, Harald,
Klaeger, Susan,
Kuster, Bernhard,
Böhmer, Frank D.,
Fiebig, Heinz-Herbert,
Krämer, Oliver H. and
Mahboobi, Siavosh
(2020)
A series of novel aryl-methanone derivatives as inhibitors of FMS-like tyrosine kinase 3 (FLT3) in FLT3-ITD-positive acute myeloid leukemia.
European Journal of Medicinal Chemistry 193, p. 112232.
Fulltext not available.
Fleischmann, Daniel,
Maslanka-Figueroa, Sara,
Beck, Sebastian,
Abstiens, Kathrin,
Witzgall, Ralph,
Schweda, Frank,
Tauber, Philipp and
Goepferich, Achim 
(2020)
Adenovirus-Mimetic Nanoparticles: Sequential Ligand-Receptor Interplay as a Universal Tool for Enhanced In Vitro/In Vivo Cell Identification.
ACS Applied Materials & Interfaces 12 (31), pp. 34689-34702.
Fulltext not available.
Spinnler, Katrin,
von Krüchten, Lara,
Konieczny, Adam,
Schindler, Lisa,
Bernhardt, Günther and
Keller, Max
(2020)
An Alkyne-functionalized Arginine for Solid-Phase Synthesis Enabling “Bioorthogonal” Peptide Conjugation.
ACS Medicinal Chemistry Letters 11 (3), pp. 334-339.
Fulltext not available.
Weber, Laura,
Kuck, Katrin,
Jürgenliemk, Guido,
Heilmann, Jörg,
Lipowicz, Bartosz and
Vissiennon, Cica 
(2020)
Anti-Inflammatory and Barrier-Stabilising Effects of Myrrh, Coffee Charcoal and Chamomile Flower Extract in a Co-Culture Cell Model of the Intestinal Mucosa.
Biomolecules 10 (7), p. 1033.
Fulltext not available.
Ullah, Sami,
Beer, Ronny,
Fuhr, Uwe,
Taubert, Max 
,
Zeitlinger, Markus,
Kratzer, Alexander,
Dorn, Christoph,
Arshad, Usman,
Kofler, Mario and
Helbok, Raimund
(2020)
Brain Exposure to Piperacillin in Acute Hemorrhagic Stroke Patients Assessed by Cerebral Microdialysis and Population Pharmacokinetics.
Neurocritical Care.
Liebchen, Uwe,
Dorn, Christoph 
,
Kees, Martin,
Schiesser, Selina,
Hitzenbichler, Florian,
Kees, Frieder and
Paal, Michael
(2020)
Comment on “Meropenem, Cefepime, and Piperacillin Protein Binding in Patient Samples”.
Therapeutic Drug Monitoring 42 (6), pp. 909-910.
Fulltext not available.
Bohley, Marilena S.,
Birch, Emily,
Baumann, Felix J.,
Dillinger, Andrea E.,
Tamm, Ernst R. and
Goepferich, Achim M.
(2020)
Design of dye and superparamagnetic iron oxide nanoparticle loaded lipid nanocapsules with dual detectability in vitro and in vivo.
International Journal of Pharmaceutics 585, p. 119433.
Fulltext not available.
Schihada, Hannes 
,
Ma, Xiaoyuan,
Zabel, Ulrike,
Vischer, Henry F.,
Schulte, Gunnar 
,
Leurs, Rob,
Pockes, Steffen 
and
Lohse, Martin J. 
(2020)
Development of a Conformational Histamine H3 Receptor Biosensor for the Synchronous Screening of Agonists and Inverse Agonists.
ACS Sensors 5 (6), pp. 1734-1742.
Fulltext not available.
Gruber, Corinna G.,
Pegoli, Andrea,
Müller, Christoph,
Grätz, Lukas,
She, Xueke and
Keller, Max
(2020)
Differently fluorescence-labelled dibenzodiazepinone-type muscarinic acetylcholine receptor ligands with high M2R affinity.
RSC Medicinal Chemistry 11 (7), pp. 823-832.
Fulltext not available.
Andreev, Stanislav,
Pantsar, Tatu 
,
El-Gokha, Ahmed,
Ansideri, Francesco,
Kudolo, Mark,
Anton, Débora Bublitz,
Sita, Giulia 
,
Romasco, Jenny,
Geibel, Christian,
Lämmerhofer, Michael 
,
Goettert, Márcia Ines,
Tarozzi, Andrea,
Laufer, Stefan A. and
Koch, Pierre
(2020)
Discovery and Evaluation of Enantiopure 9H-pyrimido[4,5-b]indoles as Nanomolar GSK-3β Inhibitors with Improved Metabolic Stability.
International Journal of Molecular Sciences 21 (21), p. 7823.
Fulltext not available.
Keller, Max,
Mahuroof, Shahani A.,
Hong Yee, Vivyanne,
Carpenter, Jessica,
Schindler, Lisa,
Littmann, Timo,
Pegoli, Andrea,
Hübner, Harald,
Bernhardt, Günther,
Gmeiner, Peter 
and
Holliday, Nicholas D. 
(2020)
Fluorescence Labeling of Neurotensin(8–13) via Arginine Residues Gives Molecular Tools with High Receptor Affinity.
ACS Medicinal Chemistry Letters 11 (1), pp. 16-22.
Fulltext not available.
Biselli, Sabrina,
Alencastre, Inês,
Tropmann, Katharina,
Erdmann, Daniela,
Chen, Mengya,
Littmann, Timo,
Maia, André F. 
,
Gomez-Lazaro, Maria,
Tanaka, Miho,
Ozawa, Takeaki,
Keller, Max,
Lamghari, Meriem,
Buschauer, Armin and
Bernhardt, Günther
(2020)
Fluorescent H2 Receptor Squaramide-Type Antagonists: Synthesis, Characterization, and Applications.
ACS Medicinal Chemistry Letters 11 (8), pp. 1521-1528.
Fulltext not available.
Sommer, Judith,
Dorn, Christoph 
,
Gäbele, Erwin,
Bataille, Frauke,
Freese, Kim,
Seitz, Tatjana,
Thasler, Wolfgang E.,
Büttner, Reinhard,
Weiskirchen, Ralf 
,
Bosserhoff, Anja 
and
Hellerbrand, Claus
(2020)
Four-And-A-Half LIM-Domain Protein 2 (FHL2) Deficiency Aggravates Cholestatic Liver Injury.
Cells 9 (1), p. 248.
Apaolaza, P.S. 
,
Busch, M.,
Asin-Prieto, E. 
,
Peynshaert, K. 
,
Rathod, R.,
Remaut, K.,
Dünker, N. and
Göpferich, A.
(2020)
Hyaluronic acid coating of gold nanoparticles for intraocular drug delivery: Evaluation of the surface properties and effect on their distribution.
Experimental Eye Research 198, p. 108151.
Fulltext not available.
Biswas, Siladitta,
Kojonazarov, Baktybek,
Hadzic, Stefan,
Majer, Michael,
Bajraktari, Ganimete,
Novoyatleva, Tatyana,
Ghofrani, Hossein Ardeschir,
Grimminger, Friedrich,
Seeger, Werner,
Weissmann, Norbert,
Schlossmann, Jens and
Schermuly, Ralph Theo
(2020)
IRAG1 Deficient Mice Develop PKG1β Dependent Pulmonary Hypertension.
Cells 9 (10), p. 2280.
Fulltext not available.
Yagati, Ajay Kumar 
,
Behrent, Arne,
Beck, Sebastian,
Rink, Simone,
Goepferich, Achim M.,
Min, Junhong 
,
Lee, Min-Ho 
and
Baeumner, Antje J. 
(2020)
Laser-induced graphene interdigitated electrodes for label-free or nanolabel-enhanced highly sensitive capacitive aptamer-based biosensors.
Biosensors and Bioelectronics 164, p. 112272.
Fulltext not available.
Simon, Philipp 
,
Busse, David 
,
Petroff, David 
,
Dorn, Christoph 
,
Ehmann, Lisa,
Hochstädt, Sophie,
Girrbach, Felix,
Dietrich, Arne,
Zeitlinger, Markus,
Kees, Frieder,
Kloft, Charlotte and
Wrigge, Hermann
(2020)
Linezolid Concentrations in Plasma and Subcutaneous Tissue are Reduced in Obese Patients, Resulting in a Higher Risk of Underdosing in Critically Ill Patients: A Controlled Clinical Pharmacokinetic Study.
Journal of Clinical Medicine 9 (4), p. 1067.
Simon, Philipp,
Petroff, David,
Busse, David 
,
Heyne, Jana,
Girrbach, Felix,
Dietrich, Arne,
Kratzer, Alexander Ludwig,
Zeitlinger, Markus,
Kloft, Charlotte,
Kees, Frieder,
Wrigge, Hermann and
Dorn, Christoph
(2020)
Meropenem Plasma and Interstitial Soft Tissue Concentrations in Obese and Nonobese Patients—A Controlled Clinical Trial.
Antibiotics 9 (12), p. 931.
Pontes de Sousa, Ingrid,
Ferreira, Antônio Gilberto 
,
Miller Crotti, Antônio Eduardo,
Alves dos Santos, Raquel,
Kiermaier, Josef,
Kraus, Birgit,
Heilmann, Jörg and
Jacometti Cardoso Furtado, Niege Araçari
(2020)
New antifungal ent-labdane diterpenes against Candida glabrata produced by microbial transformation of ent-polyalthic acid.
Bioorganic Chemistry 95, p. 103560.
Fulltext not available.
Rustler, Karin 
,
Gomila, Alexandre 
,
Maleeva, Galyna,
Gorostiza, Pau 
,
Bregestovski, Piotr 
and
König, Burkhard 
(2020)
Optical Control of GABAA Receptors with a Fulgimide‐Based Potentiator.
Chemistry - A European Journal 26, pp. 12722-12727.
Rustler, Karin 
,
Nitschke, Philipp,
Zahnbrecher, Sophie,
Zach, Julia,
Crespi, Stefano 
and
König, Burkhard 
(2020)
Photochromic evaluation of 3(5)-arylazo-1H-pyrazoles.
The Journal of Organic Chemistry 85, pp. 4079-4088.
Fulltext not available.
Piacentino, Daria 
,
Kotzalidis, Georgios D. 
,
Schoretsanitis, Georgios 
,
Paulzen, Michael,
Haen, Ekkehard,
Cappelletti, Simone,
Giupponi, Giancarlo,
Grözinger, Michael and
Conca, Andreas
(2020)
Plasma Risperidone-related Measures in Children and Adolescents with Oppositional Defiant/Conduct Disorders.
Clinical Psychopharmacology and Neuroscience 18 (1), pp. 41-48.
Fulltext not available.
Busse, David 
,
Simon, Philipp,
Michelet, Robin 
,
Ehmann, Lisa,
Mehner, Frank,
Dorn, Christoph 
,
Kratzer, Alexander,
Huisinga, Wilhelm,
Wrigge, Hermann 
,
Petroff, David and
Kloft, Charlotte
(2020)
Quantification of microdialysis related variability in humans: Clinical trial design recommendations.
European Journal of Pharmaceutical Sciences, p. 105607.
Fulltext not available.
She, Xueke,
Pegoli, Andrea,
Gruber, Corinna G.,
Wifling, David 
,
Carpenter, Jessica,
Hübner, Harald,
Chen, Mengya,
Wan, Jianfei,
Bernhardt, Günther,
Gmeiner, Peter 
,
Holliday, Nicholas D. 
and
Keller, Max
(2020)
Red-Emitting Dibenzodiazepinone Derivatives as Fluorescent Dualsteric Probes for the Muscarinic Acetylcholine M2 Receptor.
Journal of Medicinal Chemistry 63 (8), pp. 4133-4154.
Fulltext not available.
Ehmann, L.,
Simon, P.,
Busse, D.,
Petroff, D.,
Dorn, Christoph 
,
Huisinga, W.,
Dietrich, A.,
Zeitlinger, M.,
Wrigge, H. and
Kloft, C.
(2020)
Risk of target non-attainment In obese compared to non-obese patients In Calculated linezolid therapy.
Clinical Microbiology and Infection.
Fulltext not available.
Stolwijk, Judith A.,
Mildner, Anne-Kathrin,
Kade, Christian,
Skiba, Michael,
Bernhardt, Guenther,
Buschauer, Armin,
Huebner, Harald,
Gmeiner, Peter and
Wegener, Joachim
(2020)
Stepwise Dosing Protocol for Increased Throughput in Label-Free Impedance-Based GPCR Assays.
Journal of Visualized Experiments (156).
Fulltext not available.
Antoni, Frauke,
Bause, Manuel,
Scholler, Matthias,
Bauer, Stefanie,
Stark, Simone Alexandra,
Jackson, Scott M.,
Manolaridis, Ioannis,
Locher, Kaspar P.,
König, Burkhard 
,
Buschauer, Armin and
Bernhardt, Günther
(2020)
Tariquidar-related triazoles as potent, selective and stable inhibitors of ABCG2 (BCRP).
European Journal of Medicinal Chemistry 191.
Fulltext not available.
Kuzin, Maxim 
,
Schoretsanitis, Georgios 
,
Haen, Ekkehard,
Dammann, Gerhard,
Hiemke, Christoph,
Gründer, Gerhard and
Paulzen, Michael
(2020)
The Effects of Co-prescription of Pantoprazole on the Clozapine Metabolism.
Pharmacopsychiatry 53 (02), pp. 65-70.
Fulltext not available.
Maschauer, Simone,
Ott, Julian J. 
,
Bernhardt, Günther,
Kuwert, Torsten,
Keller, Max and
Prante, Olaf
(2019)
18F-labelled triazolyl-linked argininamides targeting the neuropeptide Y Y1R for PET Imaging of mammary carcinoma.
Scientific Reports 9, p. 12990.
Schramm, Andrea,
Schweda, Frank,
Sequeira-Lopez, Maria Luisa S.,
Hofmann, Franz,
Sandner, Peter and
Schlossmann, Jens
(2019)
Protein Kinase G Is Involved in Acute but Not in Long-Term Regulation of Renin Secretion.
Frontiers in Pharmacology 2019 (10), p. 800.
Dorn, Christoph,
Petroff, David,
Neumann, Nancy,
Kratzer, Alexander,
El-Najjar, Nahed 
,
Dietrich, Arne,
Kloft, Charlotte,
Zeitlinger, Markus 
,
Kees, Martin,
Kees, Frieder,
Wrigge, Hermann and
Simon, Philipp
(2019)
Plasma and tissue pharmacokinetics of fosfomycin in morbidly obese and non-obese surgical patients: a controlled clinical trial.
Journal of Antimicrobial Chemotherapy.
Fulltext not available.
Pegoli, Andrea,
Wifling, David 
,
Gruber, Corinna G.,
Xueke, She,
Hübner, Harald,
Bernhardt, Günther,
Gmeiner, Peter 
and
Keller, Max
(2019)
Conjugation of Short Peptides to Dibenzodiazepinone-Type
Muscarinic Acetylcholine Receptor Ligands Determines M2R
Selectivity.
Journal of Medicinal Chemistry 62, pp. 5358-5369.
Fulltext not available.
Schramm, Simon,
Agnetta, Luca,
Bermudez, Marcel,
Gerwe, Hubert,
Irmen, Matthias,
Holze, Janine,
Littmann, Timo,
Wolber, Gerhard 
,
Tränkle, Christian and
Decker, Michael
(2019)
Novel BQCA‐ and TBPB‐Derived M 1 Receptor Hybrid Ligands: Orthosteric Carbachol Differentially Regulates Partial Agonism.
ChemMedChem 14 (14), pp. 1349-1358.
Fulltext not available.
Maleeva, Galyna 
,
Wutz, Daniel,
Rustler, Karin 
,
Nin-Hill, Alba,
Alfonso-Prieto, Mercedes 
,
Petukhova, Elena 
,
Bautista-Barrufet, Antoni,
Gomila-Juaneda, Alexandre,
Scholze, Petra 
,
Peiretti, Franck,
Rovira, Carme 
,
König, Burkhard 
,
Gorostiza, Pau and
Bregestovski, Piotr
(2019)
A photoswitchable GABA receptor channel blocker.
British Journal of Pharmacology 176, pp. 2661-2677.
Fulltext not available.
Dechant, Franz-Xaver,
Dechant, Rebecca,
Kandulski, Arne,
Selgrad, Michael,
Weber, Florian,
Reischl, Udo,
Wilczek, Wolf,
Mueller, Martina and
Weigand, Kilian 
(2019)
Accuracy of Different Rapid Urease Tests in Comparison with Histopathology in Patients with Endoscopic Signs of Gastritis.
Digestion 101 (2), pp. 184-190.
Fulltext not available.
Łażewska, Dorota 
,
Mogilski, Szczepan,
Hagenow, Stefanie 
,
Kuder, Kamil,
Głuch-Lutwin, Monika 
,
Siwek, Agata 
,
Więcek, Małgorzata,
Kaleta, Maria,
Seibel, Ulla,
Buschauer, Armin,
Filipek, Barbara,
Stark, Holger 
and
Kieć-Kononowicz, Katarzyna
(2019)
Alkyl derivatives of 1,3,5-triazine as histamine H4 receptor ligands.
Bioorganic & Medicinal Chemistry 27 (7), pp. 1254-1262.
Fulltext not available.
Polykandriotis, Elias,
Horch, Raymund E.,
Jost, Matthias,
Arkudas, Andreas,
Kees, Frieder and
Schmitz, Marweh
(2019)
Can systemically administered antibiotics be detected in wound tissues and surfaces under negative pressure wound therapy?
International Wound Journal 16 (2), pp. 503-510.
Fulltext not available.
Kowalewski, Christoph,
Haen, Ekkehard,
Hiemke, Christoph,
Ridders, Florian,
Endres, Katharina,
Gründer, Gerhard,
Paulzen, Michael and
Schoretsanitis, Georgios
(2019)
Cytochrome P450-mediated inhibition of venlafaxine metabolism by trimipramine.
International Clinical Psychopharmacology 34 (5), pp. 241-246.
Fulltext not available.
Dorn, Christoph 
,
Kratzer, Alexander Ludwig,
Schießer, Selina,
Kees, Frieder 
,
Wrigge, Hermann and
Simon, Philipp
(2019)
Determination of total or free cefazolin and metronidazole in human plasma or interstitial fluid by HPLC-UV for pharmacokinetic studies in man.
Journal of Chromatography B.
Fulltext not available.
Veselinović, Tanja,
Scharpenberg, Martin,
Heinze, Martin,
Cordes, Joachim,
Mühlbauer, Bernd,
Juckel, Georg,
Rüther, Eckart,
Paulzen, Michael,
Haen, Ekkehard,
Hiemke, Christoph,
Timm, Jürgen,
Gründer, Gerhard,
make_name_string expected hash reference,
make_name_string expected hash reference,
make_name_string expected hash reference,
make_name_string expected hash reference,
make_name_string expected hash reference,
make_name_string expected hash reference,
make_name_string expected hash reference,
make_name_string expected hash reference,
make_name_string expected hash reference 
,
make_name_string expected hash reference,
make_name_string expected hash reference,
make_name_string expected hash reference,
make_name_string expected hash reference,
make_name_string expected hash reference,
make_name_string expected hash reference,
make_name_string expected hash reference,
make_name_string expected hash reference,
make_name_string expected hash reference,
make_name_string expected hash reference,
make_name_string expected hash reference and
make_name_string expected hash reference
(2019)
Dopamine D2 Receptor Occupancy Estimated From Plasma Concentrations of Four Different Antipsychotics and the Subjective Experience of Physical and Mental Well-Being in Schizophrenia.
Journal of Clinical Psychopharmacology 39 (6), pp. 550-560.
Fulltext not available.
Agnetta, Luca,
Bermudez, Marcel 
,
Riefolo, Fabio 
,
Matera, Carlo 
,
Claro, Enrique 
,
Messerer, Regina,
Littmann, Timo,
Wolber, Gerhard 
,
Holzgrabe, Ulrike and
Decker, Michael
(2019)
Fluorination of Photoswitchable Muscarinic Agonists Tunes Receptor Pharmacology and Photochromic Properties.
Journal of Medicinal Chemistry 62 (6), pp. 3009-3020.
Fulltext not available.
Stolwijk, J. A.,
Skiba, M.,
Kade, C.,
Bernhardt, G.,
Buschauer, Armin 
,
Hübner, H.,
Gmeiner, P. and
Wegener, Joachim 
(2019)
Increasing the throughput of label-free cell assays to study the activation of G-protein-coupled receptors by using a serial agonist exposure protocol.
Integrative Biology 11 (3), pp. 99-108.
Fulltext not available.
Gergs, U. 
,
Bernhardt, Günther,
Buchwalow, I. B.,
Edler, H.,
Fröba, J.,
Keller, Max,
Kirchhefer, U.,
Köhler, F.,
Mißlinger, N.,
Wache, H. and
Neumann, J.
(2019)
Initial Characterization of Transgenic Mice Overexpressing Human Histamine H2 Receptors.
Journal of Pharmacology and Experimental Therapeutics 369 (1), pp. 129-141.
Fulltext not available.
Nussbaumer-Pröll, Alina Karoline,
Eberl, Sabine,
Reiter, Birgit,
Stimpfl, Thomas,
Dorn, Christoph 
and
Zeitlinger, Markus
(2019)
Low pH reduces the activity of ceftolozane/tazobactam in human urine, but confirms current breakpoints for urinary tract infections.
Journal of Antimicrobial Chemotherapy.
Fulltext not available.
Simon, P.,
Petroff, D.,
Dorn, Christoph 
,
Ehmann, L.,
Kloft, C.,
Prettin, C.,
Dietrich, A.,
Zeitlinger, M.,
Kees, F. and
Wrigge, H.
(2019)
Measurement of soft tissue drug concentrations in morbidly obese and non-obese patients – A prospective, parallel group, open-labeled, controlled, phase IV, single center clinical trial.
Contemporary Clinical Trials Communications 15, p. 100375.
Fulltext not available.
Schoretsanitis, Georgios 
,
Haen, Ekkehard,
Hiemke, Christoph,
Endres, Katharina,
Ridders, Florian,
Veselinovic, Tanja,
Gründer, Gerhard and
Paulzen, Michael
(2019)
Pharmacokinetic correlates of venlafaxine: associated adverse reactions.
European Archives of Psychiatry and Clinical Neuroscience 269 (7), pp. 851-857.
Fulltext not available.
Heider, Fabian 
,
Pantsar, Tatu,
Kudolo, Mark,
Ansideri, Francesco,
De Simone, Angela,
Pruccoli, Letizia,
Schneider, Taiane,
Goettert, Marcia Ines,
Tarozzi, Andrea,
Andrisano, Vincenza,
Laufer, Stefan A. and
Koch, Pierre
(2019)
Pyridinylimidazoles as GSK3β Inhibitors: The Impact of Tautomerism on Compound Activity via Water Networks.
ACS Medicinal Chemistry Letters 10 (10), pp. 1407-1414.
Fulltext not available.
Heider, Fabian 
,
Ansideri, Francesco,
Tesch, Roberta,
Pantsar, Tatu,
Haun, Urs,
Döring, Eva,
Kudolo, Mark,
Poso, Antti 
,
Albrecht, Wolfgang,
Laufer, Stefan A. 
and
Koch, Pierre
(2019)
Pyridinylimidazoles as dual glycogen synthase kinase 3β/p38α mitogen-activated protein kinase inhibitors.
European Journal of Medicinal Chemistry 175, pp. 309-329.
Fulltext not available.
Nowak, Hartmuth,
Weidemann, Caroline,
Martini, Stefan,
Oesterreicher, Zoe Anne,
Dorn, Christoph,
Adamzik, Michael,
Kees, Frieder,
Zeitlinger, Markus 
and
Rahmel, Tim 
(2019)
Repeated determination of moxifloxacin concentrations in interstitial space fluid of muscle and subcutis in septic patients.
Journal of Antimicrobial Chemotherapy.
Fulltext not available.
Makule, Edna E.,
Kraus, Birgit,
Jürgenliemk, Guido,
Heilmann, Jörg and
Wiesneth, Stefan
(2018)
Dioic acid glycosides, tannins and methylated ellagic acid glycosides from Morella salicifolia bark.
Phytochemistry Letters 28, pp. 76-83.
Fulltext not available.
Kratzer, Alexander,
Schießer, Selina,
Matzneller, Peter,
Wulkersdorfer, Beatrix,
Zeitlinger, Markus 
,
Schlossmann, Jens 
,
Kees, Frieder 
and
Dorn, Christoph
(2018)
Determination of Total and Free Ceftolozane and Tazobactam in Human Plasma and Interstitial Fluid by HPLC-UV.
Journal of Pharmaceutical and Biomedical Analysis.
Fulltext not available.
Yang, Zhenlin,
Han, Shuo,
Keller, Max,
Kaiser, Anette,
Bender, Brain J.,
Bosse, Mathias,
Burkert, Kerstin,
Kögler, Lisa M.,
Wifling, David 
,
Bernhardt, Günther,
Plank, Nicole,
Littmann, Timo,
Schmidt, Peter,
Yi, Cuiying,
Li, Beibei,
Ye, Sheng,
Zhang, Rongguang,
Xu, Bo,
Larhammar, Dan,
Stevens, Raymond C. 
,
Huster, Daniel,
Meiler, Jens,
Zhao, Qiang,
Beck-Sickinger, Annette G.,
Buschauer, Armin and
Wu, Beili
(2018)
Structural basis of ligand binding modes at the
neuropeptide Y Y1 receptor.
Nature 556, pp. 520-524.
Fulltext not available.
Schramm, Andrea,
Mueller-Thuemen, Philip,
Littmann, Timo,
Harloff, Manuela,
Ozawa, Takeaki and
Schlossmann, Jens 
(2018)
Establishing a Split Luciferase Assay for Proteinkinase G (PKG) Interaction Studies.
International Journal o f Molecular Sciences 19 (4), p. 1180.
Pockes, Steffen 
,
Wifling, David 
,
Keller, Max,
Buschauer, Armin 
and
Elz, Sigurd
(2018)
Highly Potent, Stable, and Selective Dimeric Hetarylpropylguanidine-Type Histamine H2 Receptor Agonists.
ACS Omega 2018 (3), pp. 2865-2882.
Walz, J. M.,
Bemme, S.,
Reichl, S.,
Akman, S.,
Breuß, H.,
Süsskind, D.,
Glitz, B.,
Müller, V. C.,
Wagenfeld, L.,
Gabel-Pfisterer, A.,
Aisenbrey, S.,
Engelmann, K.,
Koutsonas, A.,
Krohne, T. U. and
Stahl, A. 
(2018)
Behandelte Frühgeborenenretinopathie in Deutschland.
Der Ophthalmologe 115 (6), pp. 476-488.
Fulltext not available.
Dorn, Christoph,
Kratzer, Alexander,
Liebchen, Uwe,
Schleibinger, Michael,
Murschhauser, Alexandra,
Schlossmann, Jens 
,
Kees, Frieder,
Simon, Philipp and
Kees, Martin G.
(2018)
Impact of Experimental Variables on the Protein Binding of Tigecycline in Human Plasma as Determined by Ultrafiltration.
Journal of Pharmaceutical Sciences 107 (2), pp. 739-744.
Fulltext not available.
Dillinger, Andrea E.,
Guter, Michaela,
Froemel, Franziska,
Weber, Gregor R.,
Perkumas, Kristin,
Stamer, W. Daniel,
Ohlmann, Andreas,
Fuchshofer, Rudolf and
Breunig, Miriam 
(2018)
Intracameral Delivery of Layer‐by‐Layer Coated siRNA Nanoparticles for Glaucoma Therapy.
Small 14 (50), p. 1803239.
Fulltext not available.
Sellmer, Andreas,
Stangl, Hubert,
Beyer, Mandy,
Grünstein, Elisabeth,
Leonhardt, Michel,
Pongratz, Herwig,
Eichhorn, Emerich,
Elz, Sigurd,
Striegl, Birgit,
Jenei-Lanzl, Zsuzsa,
Dove, Stefan,
Straub, Rainer H.,
Krämer, Oliver H. and
Mahboobi, Siavosh
(2018)
Marbostat-100 Defines a New Class of Potent and Selective Antiinflammatory and Antirheumatic Histone Deacetylase 6 Inhibitors.
Journal of Medicinal Chemistry 61 (8), pp. 3454-3477.
Fulltext not available.
Schoretsanitis, Georgios,
de Leon, Jose,
Haen, Ekkehard,
Stegmann, Benedikt,
Hiemke, Christoph,
Gründer, Gerhard and
Paulzen, Michael
(2018)
Pharmacokinetics of risperidone in different application forms – Comparing long-acting injectable and oral formulations.
European Neuropsychopharmacology 28 (1), pp. 130-137.
Fulltext not available.
Mathioudaki, Angeliki,
Berzesta, Ariola,
Kypriotakis, Zacharias,
Skaltsa, Helen and
Heilmann, Jörg
(2018)
Phenolic metabolites from Hypericum kelleri Bald., an endemic species of Crete (Greece).
Phytochemistry 146, pp. 1-7.
Fulltext not available.
Jackson, Scott M.,
Manolaridis, Ioannis,
Kowal, Julia 
,
Zechner, Melanie,
Taylor, Nicholas M. I. 
,
Bause, Manuel,
Bauer, Stefanie,
Bartholomaeus, Ruben,
Bernhardt, Günther,
König, Burkhard 
,
Buschauer, Armin,
Stahlberg, Henning 
,
Altmann, Karl-Heinz and
Locher, Kaspar P.
(2018)
Structural basis of small-molecule inhibition of human multidrug transporter ABCG2.
Nature Structural & Molecular Biology 25 (4), pp. 333-340.
Fulltext not available.
Dolles, Dominik,
Hoffmann, Matthias,
Gunesch, Sandra,
Marinelli, Oliviero,
Möller, Jan 
,
Santoni, Giorgio,
Chatonnet, Arnaud,
Lohse, Martin J. 
,
Wittmann, Hans-Joachim,
Strasser, Andrea,
Nabissi, Massimo,
Maurice, Tangui and
Decker, Michael 
(2018)
Structure–Activity Relationships and Computational Investigations into the Development of Potent and Balanced Dual-Acting Butyrylcholinesterase Inhibitors and Human Cannabinoid Receptor 2 Ligands with Pro-Cognitive in Vivo Profiles.
Journal of Medicinal Chemistry 61 (4), pp. 1646-1663.
Fulltext not available.
Plokhikh, I. V. 
,
Charkin, D. O.,
Verchenko, V. Yu.,
Kuznetsov, A. N.,
Tsirlin, A. A.,
Kazakov, S. M. 
and
Shevelkov, A. V.
(2018)
Synthesis, crystal structure and physical properties of europium – manganese fluoride pnictides, EuMnPnF (Pn = P, As, Sb).
Journal of Solid State Chemistry 258, pp. 682-690.
Fulltext not available.
Peña-Solórzano, Diana,
Scholler, Matthias,
Bernhardt, Günther,
Buschauer, Armin 
,
König, Burkhard 
and
Ochoa-Puentes, Cristian
(2018)
Tariquidar-Related Chalcones and Ketones as ABCG2 Modulators.
ACS Medicinal Chemistry Letters 9, pp. 854-859.
Fulltext not available.
Uchida, Hitoshi,
Matsumura, Shinji,
Katano, Tayo,
Watanabe, Masahiko 
,
Schlossmann, Jens 
and
Ito, Seiji
(2018)
Two isoforms of cyclic GMP-dependent kinase-I exhibit distinct expression patterns in the adult mouse dorsal root ganglion.
Molecular Pain 14, p. 174480691879640.
Fulltext not available.
She, Xueke,
Pegoli, Andrea,
Mayr, Judith,
Hübner, Harald,
Bernhardt, Günther 
,
Gmeiner, Peter and
Keller, Max 
(2017)
Heterodimerization of Dibenzodiazepinone-Type Muscarinic Acetylcholine Receptor Ligands Leads to Increased M2R Affinity and Selectivity.
ACS Omega 2 (10), pp. 6741-6754.
Dessauer, Carmen W.,
Watts, Val J.,
Ostrom, Rennolds S.,
Conti, Marco,
Dove, Stefan and
Seifert, Roland
(2017)
International Union of Basic and Clinical Pharmacology. CI. Structures and Small Molecule Modulators of Mammalian Adenylyl Cyclases.
Pharmacological Reviews 69 (2), pp. 93-139.
Fulltext not available.
Schlossmann, Jens,
Schinner, Elisabeth,
Wetzl, Veronika,
Schramm, Andrea,
Kees, Frieder,
Sandner, Peter,
Stasch, Johannes-Peter and
Hofmann, Franz
(2017)
Inhibition of the TGFβ signalling pathway by cGMP and cGMP‐dependent kinase I in renal fibrosis.
FEBS openbio 7 (4), pp. 550-561.
Dorn, Christoph 
,
Nowak, Hartmuth,
Weidemann, Caroline,
Martini, Stefan,
Zeitlinger, Markus,
Adamzik, Michael and
Kees, Frieder K.
(2017)
Decreased protein binding of moxifloxacin in patients with sepsis?
GMS Infectious Diseases 2017 (5), Doc03.
Schäfer, Claudia,
Göder, Anja,
Beyer, Mandy,
Kiweler, Nicole,
Mahendrarajah, Nisintha,
Rauch, Anke,
Nikolova, Teodora,
Stojanovic, Natasa,
Wieczorek, Martin,
Reich, Thomas R.,
Tomicic, Maja T.,
Linnebacher, Michael,
Sonnemann, Jürgen,
Dietrich, Sascha,
Sellmer, Andreas,
Mahboobi, Siavosh,
Heinzel, Thorsten,
Schneider, Günter and
Krämer, Oliver H.
(2017)
Class I histone deacetylases regulate p53/NF-κB crosstalk in cancer cells.
Cellular Signalling 29, pp. 218-225.
Fulltext not available.
Stojanovic, N.,
Hassan, Z.,
Wirth, M.,
Wenzel, P.,
Beyer, M.,
Schäfer, C.,
Brand, P.,
Kroemer, A.,
Stauber, R. H.,
Schmid, R. M.,
Arlt, A.,
Sellmer, A.,
Mahboobi, S.,
Rad, R.,
Reichert, M.,
Saur, D.,
Krämer, O. H. and
Schneider, G.
(2017)
HDAC1 and HDAC2 integrate the expression of p53 mutants in pancreatic cancer.
Oncogene 36 (13), pp. 1804-1815.
Fulltext not available.
Mahendrarajah, Nisintha,
Borisova, Marina E.,
Reichardt, Sigrid,
Godmann, Maren,
Sellmer, Andreas,
Mahboobi, Siavosh,
Haitel, Andrea,
Schmid, Katharina,
Kenner, Lukas 
,
Heinzel, Thorsten,
Beli, Petra and
Krämer, Oliver H.
(2017)
HSP90 is necessary for the ACK1-dependent phosphorylation of STAT1 and STAT3.
Cellular Signalling 39, pp. 9-17.
Fulltext not available.
Kuhn, Kilian K.,
Littmann, Timo,
Dukorn, Stefanie,
Tanaka, Miho,
Keller, Max,
Ozawa, Takeaki,
Bernhardt, Günther and
Buschauer, Armin 
(2017)
In Search of NPY Y4R Antagonists: Incorporation of Carbamoylated Arginine, Aza-Amino Acids, or d-Amino Acids into Oligopeptides Derived from the C-Termini of the Endogenous Agonists.
ACS Omega 2 (7), pp. 3616-3631.
Wutz, Daniel-Fabian,
Gluhacevic, Dino,
Chakrabarti, A.,
Schmidtkunz, K.,
Robaa, D.,
Erdmann, F.,
Romier, C.,
Sippl, W.,
Jung, M. and
König, Burkhard 
(2017)
Photochromic histone deacetylase inhibitors based on
dithienylethenes and fulgimides.
Organic & Biomolecular Chemistry 15, pp. 4882-4896.
Fulltext not available.
Pegoli, Andrea 
,
She, Xueke,
Wifling, David 
,
Hübner, Harald,
Bernhardt, Günther,
Gmeiner, Peter 
and
Keller, Max
(2017)
Radiolabeled Dibenzodiazepinone-Type Antagonists Give Evidence of Dualsteric Binding at the M2 Muscarinic Acetylcholine Receptor.
Journal of Medicinal Chemistry 60 (8), pp. 3314-3334.
Fulltext not available.
Lieb, Sebastian,
Littmann, Timo,
Plank, Nicole,
Felixberger, Johannes,
Tanaka, Miho,
Schäfer, Thorsten,
Krief, Stéphane,
Elz, Sigurd,
Friedland, Kristina,
Bernhardt, Günther,
Wegener, Joachim,
Ozawa, Takeaki and
Buschauer, Armin
(2016)
Label-free versus conventional cellular assays: functional investigations on the human histamine H1 receptor.
Pharmacological Research 114, pp. 13-26.
Fulltext not available.
Töpper, Christoph,
Steinbach, Cathérine Louise,
Dorn, Christoph 
,
Kratzer, Alexander,
Wicha, Sebastian G.,
Schleibinger, Michael,
Liebchen, Uwe,
Kees, Frieder,
Salzberger, Bernd and
Kees, Martin G.
(2016)
Variable linezolid exposure in ICU patients—possible role of drug-drug interactions.
Therapeutic Drug Monitoring 38 (5), pp. 573-578.
Fulltext not available.
Naporra, Franziska,
Gobleder, Susanne,
Wittmann, Hans-Joachim,
Spindler, Julia,
Bodensteiner, Michael,
Bernhardt, Günther,
Hübner, Harald,
Gmeiner, Peter,
Elz, Sigurd and
Strasser, Andrea
(2016)
Dibenzo[b,f][1,4]oxazepines and dibenzo[b,e]oxepines: Influence of the chlorine substitution pattern on the pharmacology at the H1R, H4R, 5-HT2AR and other selected GPCRs.
Pharmacological Research 113, pp. 610-625.
(In Press)
Fulltext not available.
Schlossmann, Jens,
Wetzl, Veronika,
Schinner, Elisabeth,
Kees, Frieder K.,
Hofmann, Franz and
Faerber, Lothar 
(2016)
Involvement of cyclic guanosine monophosphate-dependent protein kinase I in renal antifibrotic effects of serelaxin.
Frontiers in Pharmacology 7 (195), pp. 1-27.
Kuhn, Kilian K.,
Ertl, Thomas,
Dukorn, Stefanie,
Keller, Max,
Bernhardt, Günther,
Reiser, Oliver 
and
Buschauer, Armin
(2016)
High affinity agonists of the neuropeptide Y (NPY) Y4 receptor derived from the C-terminal pentapeptide of human pancreatic polypeptide (hPP): synthesis, stereochemical discrimination and radiolabeling.
Journal of Medicinal Chemistry 59 (13), pp. 6045-6058.
Fulltext not available.
Edalat, Lena,
Stegen, Benjamin,
Klumpp, Lukas,
Haehl, Erik,
Schilbach, Karin,
Lukowski, Robert,
Kühnle, Matthias,
Bernhardt, Günther,
Buschauer, Armin,
Zips, Daniel,
Ruth, Peter and
Huber, Stephan M.
(2016)
BK K+ channel blockade inhibits radiation-induced migration/brain infiltration of glioblastoma cells.
Oncotarget 7 (12), pp. 14259-14278.
Fulltext not available.
Lorenz, Peter,
Knittel, Diana N.,
Conrad, Jürgen,
Lotter, Eva M.,
Heilmann, Jörg,
Stintzing, Florian C. and
Kammerer, Dietmar R.
(2016)
1-Acetyl-3-[(3R)-hydroxyfatty acyl]glycerols: Lipid Compounds fromEuphrasia rostkovianaHayneandE. tetraquetra(Bréb.)Arrond.
Chemistry & Biodiversity 13 (5), pp. 602-612.
Fulltext not available.
Hammer, Sebastian,
Gobleder, Susanne,
Naporra, Franziska,
Wittmann, Hans-Joachim,
Elz, Sigurd,
Heinrich, Markus 
and
Strasser, Andrea
(2016)
2,4-Diaminopyrimidines as dual ligands at the histamine H1 and H4 receptor - H1/H4-receptor selectivity.
Bioorganic & Medicinal Chemistry Letters 26, pp. 292-300.
Fulltext not available.
Dolles, Dominik,
Nimczick, Martin,
Scheiner, Matthias,
Ramler, Jacqueline,
Stadtmüller, Patricia,
Sawatzky, Edgar,
Drakopoulos, Antonios,
Sotriffer, Christoph,
Wittmann, Hans-Joachim,
Strasser, Andrea and
Decker, Michael
(2016)
Aminobenzimidazoles and structural isomers as templates for dual-acting butyrylcholinesterase inhibitors and hCB2R ligands to combat neurodegenerative disorders.
ChemMedChem 11 (12), pp. 1270-1283.
Fulltext not available.
Bucher, Felicitas 
,
Walz, Johanna M.,
Bühler, Anima,
Aguilar, Edith,
Lange, Clemens,
Diaz-Aguilar, Sophia,
Martin, Gottfried,
Schlunck, Günther,
Agostini, Hansjürgen,
Friedlander, Martin and
Stahl, Andreas
(2016)
CNTF Attenuates Vasoproliferative Changes Through Upregulation of SOCS3 in a Mouse-Model of Oxygen-Induced Retinopathy.
Investigative Opthalmology & Visual Science 57 (10), p. 4017.
Fulltext not available.
Sawatzky, Edgar,
Wehle, Sarah,
Kling, Beata,
Wendrich, Jan,
Bringmann, Gerhard,
Sotriffer, Christoph A.,
Heilmann, Jörg and
Decker, Michael
(2016)
Discovery of Highly Selective and Nanomolar Carbamate-Based Butyrylcholinesterase Inhibitors by Rational Investigation into Their Inhibition Mode.
Journal of Medicinal Chemistry 59 (5), pp. 2067-2082.
Fulltext not available.
Kariminia, Amina,
Holtan, Shernan G.,
Ivison, Sabine,
Rozmus, Jacob,
Hebert, Marie-Josée,
Martin, Paul J.,
Lee, Stephanie J.,
Wolff, Daniel,
Subrt, Peter,
Abdossamadi, Sayeh,
Sung, Susanna,
Storek, Jan,
Levings, Megan,
Aljurf, Mahmoud,
Arora, Mukta,
Cutler, Corey,
Gallagher, Geneviève,
Kuruvilla, John,
Lipton, Jeff,
Nevill, Thomas J.,
Newell, Laura F.,
Panzarella, Tony,
Pidala, Joseph,
Popradi, Gizelle,
Szwajcer, David,
Tay, Jason 
,
Toze, Cynthia L.,
Walker, Irwin,
Couban, Stephen,
Storer, Barry E. and
Schultz, Kirk R. 
(2016)
Heterogeneity of chronic graft-versus-host disease biomarkers: association with CXCL10 and CXCR3+ NK cells.
Blood 127 (24), pp. 3082-3091.
Fulltext not available.
Dove, Stefan
(2016)
Mammalian Nucleotidyl Cyclases and Their Nucleotide Binding Sites.
In:
Seifert, Roland, (ed.)
Non-canonical Cyclic Nucleotides.
Handbook of Experimental Pharmacology, 238.
Springer International Publishing, Cham, Switzerland, pp. 49-66.
ISBN 978-3-319-52673-7 (online), 978-3-319-52671-3 (print).
Fulltext not available.
Keller, Max,
Kuhn, Kilian K.,
Einsiedel, Jürgen,
Hübner, Harald,
Biselli, Sabrina,
Mollereau, Catherine 
,
Wifling, David,
Svobodova, Jaroslava,
Bernhardt, Günther,
Cabrele, Chiara 
,
Vanderheyden, Patrick,
Gmeiner, Peter 
and
Buschauer, Armin
(2016)
Mimicking of arginine by functionalized Nω-carbamoylated arginine as a new broadly applicable approach to labeled bioactive peptides: high affinity angiotensin, neuropeptide Y, neuropeptide FF and neurotensin receptor ligands as examples.
Journal of Medicinal Chemistry 59 (5), pp. 1925-1945.
Fulltext not available.
Khan, Nadia,
Saad, Ali,
Nurulain, Syed M.,
Darras, Fouad H.,
Decker, Michael and
Sadek, Bassem
(2016)
The dual-acting H3 receptor antagonist and AChE inhibitor UW-MD-71 dose-dependently enhances memory retrieval and reverses dizocilpine-induced memory impairment in rats.
Behavioural Brain Research 297, pp. 155-164.
Fulltext not available.
Huang, Guozheng 
,
Schramm, Simon,
Heilmann, Jörg,
Biedermann, David,
Křen, Vladimír and
Decker, Michael
(2016)
Unconventional application of the Mitsunobu reaction: Selective flavonolignan dehydration yielding hydnocarpins.
Beilstein Journal of Organic Chemistry 12, pp. 662-669.
Fulltext not available.
Werner, Kristin,
Kälble, Solveig,
Wolter, Sabine,
Schneider, Erich H. 
,
Buschauer, Armin,
Neumann, Detlef 
and
Seifert, Roland
(2015)
Flow cytometric analysis with a fluorescent formyl peptide receptor ligand as a new method to study the pharmacological profile of the histamine H2-receptor.
Naunyn Schmiedebergs Archives of Pharmacology 388 (10), pp. 1039-1052.
Fulltext not available.
Wolferstetter, Stefanie,
Reinders, Jörg,
Schwede, Frank,
Ruth, Peter,
Schinner, Elisabeth and
Schlossmann, Jens 
(2015)
Interaction of cCMP with the cGK, cAK and MAPK Kinases in Murine Tissues.
PLoS ONE 10 (5), e0126057.
Tetens, J. 
,
Heuer, C.,
Heyer, I.,
Klein, Matthias S. 
,
Gronwald, Wolfram,
Junge, W.,
Oefner, Peter J. 
,
Thaller, G. and
Krattenmacher, N.
(2015)
Polymorphisms within the APOBR gene are highly associated with milk levels of prognostic ketosis biomarkers in dairy cows.
Physiol. Genomics 47 (4), pp. 129-137.
Fulltext not available.
Wurster, Eva-Christina,
Liebl, Renate,
Michaelis, Stefanie,
Robelek, Rudolf,
Wastl, Daniel S. 
,
Giessibl, Franz J. 
,
Goepferich, Achim 
and
Breunig, Miriam 
(2015)
Oligolayer-Coated Nanoparticles: Impact of Surface Topography at the Nanobio Interface.
ACS applied materials & interfaces 7, pp. 7891-7900.
Fulltext not available.
Baumeister, Paul,
Erdmann, Daniela,
Biselli, Sabrina,
Kagermeier, Nicole,
Elz, Sigurd,
Bernhardt, Günther and
Buschauer, Armin
(2015)
3HUR-DE257: Development of a tritium-labeled squaramide-type selective histamine H2 receptor antagonist.
ChemMedChem 10 (1), pp. 83-93.
Fulltext not available.
Dolles, Dominik,
Nimczick, Martin,
Scheiner, Matthias,
Ramler, Jacqueline,
Stadtmüller, Patricia,
Sawatzky, Edgar,
Drakopoulos, Antonios 
,
Sotriffer, Christoph,
Wittmann, Hans-Joachim,
Strasser, Andrea and
Decker, Michael
(2015)
Aminobenzimidazoles and Structural Isomers as Templates for Dual-Acting Butyrylcholinesterase Inhibitors andhCB2R Ligands To Combat Neurodegenerative Disorders.
ChemMedChem 11 (12), pp. 1270-1283.
Fulltext not available.
Kirchhof, Susanne,
Gregoritza, Manuel,
Messmann, Viktoria,
Hammer, Nadine,
Göpferich, Achim 
and
Brandl, Ferdinand
(2015)
Diels-Alder hydrogels with enhanced stability: First step toward controlled release of bevacizumab.
European Journal of Pharmaceutics and Biopharmaceutics 96, pp. 217-225.
Fulltext not available.
Kirchhof, Susanne,
Abrami, Michela,
Messmann, Viktoria,
Hammer, Nadine,
Goepferich, Achim 
,
Grassi, Mario and
Brandl, Ferdinand
(2015)
Diels–Alder hydrogels for controlled antibody release: Correlation between mesh size and release rate.
Molecular Pharmaceutics 12 (9), pp. 3358-3368.
Fulltext not available.
Lübker, Carolin,
Dove, Stefan,
Tang, Wei-Jen 
,
Bieber Urbauer, Ramona J.,
Moskovitz, Jackob,
Urbauer, Jeffrey L. and
Seifert, Roland
(2015)
Different Roles of N-Terminal and C-Terminal Domains in Calmodulin for Activation of Bacillus anthracis Edema Factor.
Toxins 7 (7), pp. 2598-2614.
Kagermeier, Nicole,
Werner, Kristin,
Keller, Max,
Baumeister, Paul,
Bernhardt, Günther,
Seifert, Roland and
Buschauer, Armin
(2015)
Dimeric carbamoylguanidine-type histamine H2 receptor ligands: A new class of potent and selective agonists.
Bioorganic & Medicinal Chemistry 23 (14), pp. 3957-3969.
Fulltext not available.
Arndt, Stephanie,
Wacker, Eva,
Dorn, Christoph,
Koch, Andreas,
Saugspier, Michael,
Thasler, W. E.,
Hartmann, Arndt,
Bosserhoff, Anja-Katrin 
and
Hellerbrand, Claus
(2015)
Enhanced expression of BMP6 inhibits hepatic fibrosis in non-alcoholic fatty liver disease.
Gut 64 (6), pp. 973-981.
Strasser, Andrea and
Buschauer, Armin
(2015)
Histaminrezeptoren.
Pharmakon 3 (2), pp. 109-116.
Fulltext not available.
Kirchhof, Susanne,
Goepferich, Achim and
Brandl, Ferdinand
(2015)
Hydrogels in ophthalmic applications.
European Journal of Pharmaceutics and Biopharmaceutics 95, part B, pp. 227-238.
Fulltext not available.
Keller, Max,
Tränkle, Christian,
She, Xueke,
Pegoli, Andrea 
,
Bernhardt, Günther,
Buschauer, Armin and
Read, Roger W.
(2015)
M2 subtype preferring dibenzodiazepinone-type muscarinic receptor ligands: effect of chemical homo-dimerization on orthosteric (and allosteric?) binding.
Bioorganic & Medicinal Chemistry 23 (14), pp. 3970-3990.
Fulltext not available.
Lübker, Carolin,
Bieber-Urbauer, Ramona J.,
Moskovitz, Jackob,
Dove, Stefan,
Weisemann, Jasmin 
,
Fedorova, Maria,
Urbauer, Jeffrey L. and
Seifert, Roland
(2015)
Membranous adenylyl cyclase 1 activation is regulated by oxidation of N- and C-terminal methionine residues in calmodulin.
Biochemical Pharmacology 93 (2), pp. 196-209.
Fulltext not available.
Wifling, David 
,
Löffel, Karolin,
Nordemann, Uwe,
Strasser, Andrea,
Bernhardt, Günther,
Dove, Stefan,
Seifert, Roland and
Buschauer, Armin
(2015)
Molecular determinants for the high constitutive activity of the human histamine H4 receptor: Functional studies on orthologs and mutants.
British Journal of Pharmacology 172, pp. 785-798.
Fulltext not available.
Kaczor, Agnieszka 
,
Guixa-Gonzalez, Ramon,
Carrio, Pau,
Poso, Antti,
Dove, Stefan,
Pastor, Manuel 
and
Selent, Jana 
(2015)
Multi-Component Protein - Protein Docking Based Protocol with External Scoring for Modeling Dimers of G Protein-Coupled Receptors.
Molecular Informatics 34 (4), pp. 246-255.
Fulltext not available.
Keller, Max,
Weiss, Stefan,
Hutzler, Christoph 
,
Kuhn, Kilian K.,
Mollereau, Catherine 
,
Dukorn, Stefanie,
Schindler, Lisa,
Bernhardt, Günther,
König, Burkhard and
Buschauer, Armin
(2015)
N(omega)-carbamoylation of the argininamide moiety: an avenue to insurmountable NPY Y1 receptor antagonists and a radiolabeled selective high affinity molecular tool ([3H]UR-MK299) with extended residence time.
Journal of Medicinal Chemistry 58 (22), pp. 8834-8849.
Fulltext not available.
Kirchhof, Susanne,
Strasser, Andrea,
Wittmann, Hans-Joachim,
Messmann, Viktoria,
Hammer, Nadine,
Goepferich, Achim and
Brandl, Ferdinand
(2015)
New insights into the cross-linking and degradation mechanism of Diels–Alder hydrogels.
Journal of Materials Chemistry B 3, pp. 449-457.
Kirchhof, Susanne,
Strasser, Andrea,
Wittmann, Hans-Joachim,
Messmann, Viktoria,
Hammer, Nadine,
Goepferich, Achim M. 
and
Brandl, Ferdinand P.
(2015)
New insights into the cross-linking and degradation mechanism of Diels–Alder hydrogels.
Journal of Materials Chemistry B 3 (3), pp. 449-457.
Fulltext not available.
Aziz, Atiqullah,
Gierth, Michael,
Rink, Michael,
Schmid, Marianne,
Chun, Felix K.,
Dahlem, Roland,
Roghmann, Florian,
Palisaar, Rein-Jüri,
Noldus, Joachim,
Ellinger, Jörg 
,
Müller, Stefan C.,
Pycha, Armin,
Martini, Thomas,
Bolenz, Christian,
Moritz, Rudolf,
Herrmann, Edwin,
Keck, Bastian,
Wullich, Bernd,
Mayr, Roman,
Fritsche, Hans-Martin,
Burger, Maximilian,
Bastian, Patrick J.,
Seitz, Christian,
Brookman-May, Sabine,
Xylinas, Evanguelos,
Shariat, Shahrokh F.,
Fisch, Margit and
May, Matthias
(2015)
Optimizing outcome reporting after radical cystectomy for organ-confined urothelial carcinoma of the bladder using oncological trifecta and pentafecta.
World Journal of Urology 33 (12), pp. 1945-1950.
Fulltext not available.
Wicha, Sebastian G.,
Haak, Thomas,
Zink, Karl,
Kees, Frieder,
Kloft, Charlotte and
Kees, Martin G.
(2015)
Population pharmacokinetics and target attainment analysis of moxifloxacin in patients with diabetic foot infections.
The Journal of Clinical Pharmacology 55 (6), pp. 639-646.
Fulltext not available.
Chen, Xinyu,
Klöckner, Jessika,
Holze, Janine,
Zimmermann, Cornelia,
Seemann, Wiebke K.,
Schrage, Ramona,
Bock, Andreas 
,
Mohr, Klaus,
Tränkle, Christian,
Holzgrabe, Ulrike 
and
Decker, Michael
(2015)
Rational Design of Partial Agonists for the Muscarinic M1 Acetylcholine Receptor.
Journal of Medicinal Chemistry 58 (2), pp. 560-576.
Fulltext not available.
Huber, Stefan,
Antoni, Frauke,
Schickaneder, Christian,
Schickaneder, Helmut,
Bernhardt, Günther and
Buschauer, Armin
(2015)
Stabilities of neutral and basic esters of bendamustine in plasma compared to the parent compound: Kinetic investigations by HPLC.
Journal of Pharmaceutical and Biomedical Analysis 104, pp. 137-143.
Fulltext not available.
Reinartz, Michael T. 
,
Kälble, Solveig,
Littmann, Timo,
Ozawa, Takeaki,
Dove, Stefan,
Kaever, Volkhard,
Wainer, Irving W. and
Seifert, Roland
(2015)
Structure-bias relationships for fenoterol stereoisomers in six molecular and cellular assays at the β2-adrenoceptor.
Naunyn-Schmiedeberg's archives of pharmacology 388 (1), pp. 51-65.
Fulltext not available.
Herrnberger, Leonie,
Hennig, Robert,
Kremer, Werner,
Hellerbrand, Claus,
Goepferich, Achim 
,
Kalbitzer, Hans Robert and
Tamm, Ernst R. 
(2014)
Formation of Fenestrae in Murine Liver Sinusoids Depends on Plasmalemma Vesicle-Associated Protein and Is Required for Lipoprotein Passage.
PLoS ONE 9 (12), e115005.
Cuboni, Serena,
Devigny, Christian,
Hoogeland, Bastiaan,
Strasser, Andrea,
Pomplun, Sebastian,
Hauger, Barbara,
Höfner, Georg,
Wanner, Klaus,
Eder, Matthias 
,
Buschauer, Armin,
Holsboer, Florian and
Hausch, Felix
(2014)
Loratadine and analogs: Discovery and preliminary SAR of inhibitors of the amino acid transporter B0AT2.
Journal of Medicinal Chemistry 57 (22), pp. 9473-9479.
Fulltext not available.
Darras, Fouad,
Pockes, Steffen,
Huang, Guozheng 
,
Wehle, Sarah,
Strasser, Andrea,
Wittmann, Hans-Joachim,
Nimczick, Martin,
Sotriffer, Christoph and
Decker, Michael
(2014)
Synthesis, biological evaluation, and computational studies of tri- and tetracyclic nitrogen-bridgehead compounds as potent dual-acting AChE inhibitors and hH3 receptor antagonists.
ACS Chemical Neuroscience 5 (3), pp. 225-242.
Fulltext not available.
Kremb, Stephan,
Helfer, Markus,
Kraus, Birgit,
make_name_string expected hash reference,
make_name_string expected hash reference,
make_name_string expected hash reference,
make_name_string expected hash reference 
and
make_name_string expected hash reference 
(2014)
Aqueous Extracts of the Marine Brown Alga Lobophora variegata Inhibit HIV-1 Infection at the Level of Virus Entry into Cells.
PloS ONE 9, e103895.
Pollinger, Klaus,
Hennig, Robert,
Bauer, Stefanie,
Breunig, Miriam,
Tessmar, Joerg 
,
Buschauer, Armin,
Witzgall, Ralph 
and
Göpferich, Achim 
(2014)
Biodistribution of quantum dots in the kidney after intravenous injection.
Journal of Nanoscience and Nanotechnology 14 (5), pp. 3313-3319.
Fulltext not available.
Pannem, Rajeswara Rao,
Dorn, Christoph,
Ahlqvist, Kristofer,
Bosserhoff, Anja K. 
,
Hellerbrand, Claus and
Massoumi, Ramin
(2014)
CYLD controls c-MYC expression through the JNK-dependent signaling pathway in hepatocellular carcinoma.
Carcinogenesis 35 (2), pp. 461-468.
Huang, Guozheng 
,
Pemp, Daniela,
Stadtmüller, Patricia,
Nimczick, Martin,
Heilmann, Jörg and
Decker, Michael
(2014)
Design, synthesis and in vitro evaluation of novel uni- and bivalent ligands for the cannabinoid receptor type 1 with variation of spacer length and structure.
Bioorganic & Medicinal Chemistry Letters 24 (17), pp. 4209-4214.
Fulltext not available.
Kratzer, Alexander,
Liebchen, Uwe,
Schleibinger, Michael,
Kees, Martin G. and
Kees, Frieder
(2014)
Determination of free vancomycin, ceftriaxone, cefazolin and ertapenem in plasma by ultrafiltration: Impact of experimental conditions.
Journal of Chromatography B 961, pp. 97-102.
Fulltext not available.
Schramm, Andrea,
Schinner, Elisabeth,
Huettner, Johannes P.,
Kees, Frieder,
Tauber, Philipp,
Hofmann, Franz and
Schlossmann, Jens 
(2014)
Function of cGMP-dependent protein kinase II in volume load-induced diuresis.
Pflügers Archiv - European Journal of Physiology 466 (10), pp. 2009-2018.
Fulltext not available.
Patrucco, Enrico,
Domes, Katrin,
Sbroggió, Mauro 
,
Blaich, Anne,
Schlossmann, Jens 
,
Desch, Matthias,
Rybalkin, Sergei D.,
Beavo, Joseph A.,
Lukowski, Robert and
Hofmann, Franz
(2014)
Roles of cGMP-dependent protein kinase I (cGKI) and PDE5 in the regulation of Ang II-induced cardiac hypertrophy and fibrosis.
Proceedings of the National Academy of Sciences 111 (35), pp. 12925-12929.
Fulltext not available.
Luschmann, Christoph,
Tessmar, Joerg 
,
Schoeberl, Simon,
Strauss, O.,
Luschmann, Karl and
Goepferich, Achim 
(2014)
Self-assembling colloidal system for the ocular administration of cyclosporine A.
Cornea 33 (1), pp. 77-81.
Fulltext not available.
Nimczick, Martin,
Pemp, Daniela,
Darras, Fouad H.,
Chen, Xinyu,
Heilmann, Jörg and
Decker, Michael
(2014)
Synthesis and biological evaluation of bivalent cannabinoid receptor ligands based on hCB2R selective benzimidazoles reveal unexpected intrinsic properties.
Bioorganic & Medicinal Chemistry 22 (15), pp. 3938-3946.
Fulltext not available.
Sun, Qiu,
Schmidt, Sebastian,
Tremmel, Martina,
Heilmann, Jörg and
König, Burkhard 
(2014)
Synthesis of natural-like acylphloroglucinols with anti-proliferative, anti-oxidative and tube-formation inhibitory activity.
European Journal of Medicinal Chemistry 85, pp. 621-628.
Fulltext not available.
Geyer, Roland,
Igel, Patrick,
Kaske, Melanie,
Elz, Sigurd and
Buschauer, Armin
(2014)
Synthesis, SAR and selectivity of 2-acyl- and 2-cyano-1-hetarylalkyl-guanidines at the four histamine receptor subtypes: a bioisosteric approach.
MedChemComm 5 (1), pp. 72-81.
Fulltext not available.
Macabeo, Allan Patrick G.,
Martinez, Franze Perry A.,
Kurtán, Tibor 
,
Tóth, László,
Mándi, Attila 
,
Schmidt, Sebastian,
Heilmann, Jörg,
Alejandro, Grecebio Jonathan D.,
Knorn, Matthias,
Dahse, Hans-Martin and
Franzblau, Scott G. 
(2014)
Tetrahydroxanthene-1,3(2H)-dione Derivatives fromUvaria valderramensis.
Journal of Natural Products 77 (12), pp. 2711-2715.
Fulltext not available.
Endlich, Nicole 
,
Simon, Ole,
Goepferich, Achim 
,
Wegner, Henny,
Moeller, Marcus J.,
Rumpel, Elisabeth,
Kotb, Ahmed and
Endlich, Karlhans 
(2014)
Two-Photon Microscopy Reveals Stationary Podocytes in Living Zebrafish Larvae.
Journal of the American Society of Nephrology 25 (4), pp. 681-686.
Fulltext not available.
Liebchen, Uwe,
Kratzer, Alexander,
Wicha, Sebastian G.,
Kees, Frieder,
Kloft, Charlotte and
Kees, Martin G.
(2014)
Unbound fraction of ertapenem in intensive care unit patients.
Journal of Antimicrobial Chemotherapy 69 (11), pp. 3108-3111.
Fulltext not available.
Schickaneder, Helmut,
Buschauer, Armin,
Bernhardt, Günther,
Schickaneder, Christian,
Limmert, Michael,
Huber, Stefan,
Lubbe, Mathias and
Hofmeier, Harald
(2013)
Esters of bendamustine and related compounds, and medical use thereof.
Fulltext not available.
Schreeb, Annemarie,
Łażewska, Dorota,
Dove, Stefan,
Buschauer, Armin,
Kieć-Kononiwcz, Katarzyna and
Stark, Holger
(2013)
2. Histamine H4 receptor ligands.
In:
Stark, Holger, (ed.)
Histamine H4 receptor: a novel drug target for immunoregulation and inflammation.
Versita, London, pp. 21-62.
ISBN 9788376560564.
Fulltext not available.
Berlicki, Lukasz 
,
Kaske, Melanie,
Gutierrez-Abad, Raquel,
Bernhardt, Günther,
Illa, Ona 
,
Ortuño, Rosa,
Cabrele, Chiara 
,
Buschauer, Armin and
Reiser, Oliver 
(2013)
Replacement of Thr32 and Gln34 in the C-terminal neuropeptide Y fragment 25-36 by cis-cyclobutane- and cis-cyclopentane β-amino acids shifts selectivity toward the Y4 receptor.
Journal of Medicinal Chemistry 56 (21), pp. 8422-8431.
Fulltext not available.
Nordemann, Uwe,
Wifling, David 
,
Schnell, David,
Bernhardt, Günther,
Stark, Holger 
,
Seifert, Roland and
Buschauer, Armin
(2013)
Luciferase reporter gene assay on human, murine and rat histamine H4 receptor orthologs: correlations and discrepancies between distal and proximal readouts.
PLoS One 8 (9), e73961.
Bauer, Stefanie,
Ochoa Puentes, Cristian,
Sun, Qiu,
Bause, Manuel,
Bernhardt, Günther,
König, Burkhard 
and
Buschauer, Armin
(2013)
Quinoline carboxamide-type ABCG2 modulators: Indole and quinoline moieties as anilide replacements.
ChemMedChem 8 (11), pp. 1773-1778.
Fulltext not available.
Brunskole Hummel, Irena,
Kälble, Solveig,
Burhenne, Heike,
Reinartz, Michael T.,
Schwede, Frank,
Buschauer, Armin and
Seifert, Roland
(2013)
Dissociations in the effects of beta2-adrenergic receptor agonists on cAMP formation and superoxide production in human neutrophils: Support for the concept of functional selectivity.
PLoS One 8 (5), e64556.
Zölls, Sarah,
Gregoritza, Manuel,
Tantipolphan, Ruedeeporn,
Wiggenhorn, Michael,
Winter, Gerhard,
Friess, Wolfgang and
Hawe, Andrea
(2013)
How Subvisible Particles Become Invisible - Relevance of the Refractive Index for Protein Particle Analysis.
Journal of Pharmaceutical Sciences 102 (5), pp. 1434-1446.
Fulltext not available.
Kees, Martin Georg,
Schaeftlein, André,
Haeberle, Helene Anna,
Kees, Frieder K.,
Kloft, Charlotte and
Heininger, Alexandra
(2013)
Population pharmacokinetics and pharmacodynamic evaluation of intravenous and enteral moxifloxacin in surgical intensive care unit patients.
The Journal of antimicrobial chemotherapy.
Fulltext not available.
Ochoa-Puentes, Cristian,
Bauer, Stefanie,
Kühnle, Matthias,
Bernhardt, Günther,
Buschauer, Armin and
König, Burkhard 
(2013)
Benzanilide – Biphenyl Replacement: A Bioisosteric Approach to Quinoline Carboxamide-type ABCG2 Modulators.
ACS Medicinal Chemistry Letters 4 (4), pp. 393-396.
Fulltext not available.
Seifert, Roland,
Strasser, Andrea,
Schneider, Erich H.,
Neumann, Detlef,
Dove, Stefan and
Buschauer, Armin
(2013)
Molecular and cellular analysis of human histamine receptor subtypes.
Trends in Pharmacological Sciences 34 (1), pp. 33-58.
Fulltext not available.
Chen, Wen,
Oberwinkler, Heike,
Werner, Franziska,
Gaßner, Birgit,
Nakagawa, Hitoshi,
Feil, Robert 
,
Hofmann, Franz,
Schlossmann, Jens 
,
Dietrich, Alexander 
,
Gudermann, Thomas,
Nishida, Motohiro 
,
Del Galdo, Sabrina,
Wieland, Thomas 
and
Kuhn, Michaela
(2013)
Atrial Natriuretic Peptide–Mediated Inhibition of Microcirculatory Endothelial Ca 2+ and Permeability Response to Histamine Involves cGMP-Dependent Protein Kinase I and TRPC6 Channels.
Arteriosclerosis, Thrombosis, and Vascular Biology 33 (9), pp. 2121-2129.
Fulltext not available.
Klein, Regina,
Müller, Eva,
Kraus, Birgit,
Brunner, Gabi,
Estrine, Boris 
,
Touraud, Didier,
Heilmann, Jörg,
Kellermeier, Matthias and
Kunz, Werner 
(2013)
Biodegradability and cytotoxicity on human cell lines of choline soaps: effects of chain length and cation.
RSC Advances 3 (45), pp. 23347-23354.
Fulltext not available.
DEMİRCİ, FATİH,
YEŞİLADA, ERDEM 
,
BAŞER, KEMAL HÜSNÜ CAN,
FRANZ, GERHARD 
,
DEMİRCİ, BETÜL and
GÜRBÜZ, İLHAN 
(2013)
Comparison of the volatiles of Daphne pontica L. and D. oleoides Schreber subsp. oleoides isolated by hydro- and microdistillation methods.
Turkish Journal of Biology.
Fulltext not available.
Luschmann, Christoph,
Tessmar, Joerg 
,
Schoeberl, Simon,
Framme, Carsten,
Luschmann, Karl,
Goepferich, Achim and
make_name_string expected hash reference 
(2013)
Developing an in situ nanosuspension: A novel approach towards the efficient administration of poorly soluble drugs at the anterior eye.
European Journal of Pharmaceutical Sciences 50 (3-4), pp. 385-392.
Fulltext not available.
Tang, Chih-Hsin,
Brunskole Hummel, Irena,
Reinartz, Michael T.,
Kälble, Solveig,
Burhenne, Heike,
Schwede, Frank,
Buschauer, Armin and
Seifert, Roland
(2013)
Dissociations in the Effects of β2-Adrenergic Receptor Agonists on cAMP Formation and Superoxide Production in Human Neutrophils: Support for the Concept of Functional Selectivity.
PLoS ONE 8 (5), e64556.
Fulltext not available.
Miller, Tobias,
van Colen, G.,
Sander, B.,
Golas, M.,
Uezguen, Senta,
Weigandt, Markus and
Goepferich, Achim 
(2013)
Drug Loading of Polymerics Micelles.
Pharmaceutical Research 30 (2), pp. 484-595.
Fulltext not available.
Dietrich, P.,
Moleda, Lukas,
Kees, Frieder K.,
Müller, M.,
Straub, R. H. 
,
Hellerbrand, C. and
Wiest, R.
(2013)
Dysbalance in sympathetic neurotransmitter release and action in cirrhotic rats: impact of exogenous neuropeptide Y.
Journal of hepatology 58 (2), pp. 254-261.
Fulltext not available.
Ferstl, Matthias,
Drechsler, Markus 
,
Rachel, Reinhard,
Rischer, M.,
Engel, J.,
Backofen, Michael and
Goepferich, Achim 
(2013)
Impact of Polyelectrolyte Structure on the Shape of Nanoassemblies with Cationic Peptides.
European Journal of Pharmaceutical Sciences 102, pp. 2599-2607.
Fulltext not available.
Mueller, M.,
Blunk, Torsten,
Appel, Bernhard,
Maschke, Angelika,
Goepferich, Achim and
Zellner, J.
(2013)
Insulin is essential for in vitro chondrogenesis of mesenchymal progenitor cells and influences chondrogenesis in a dose-dependent manner.
International orthopaedics 37 (1), pp. 153-158.
Fulltext not available.
Mueller, Michael B.,
Blunk, Torsten,
Appel, Bernhard,
Maschke, Angelika,
Goepferich, Achim 
,
Zellner, Johannes 
,
Englert, Carsten 
,
Prantl, Lukas,
Kujat, Richard,
Nerlich, Michael and
Angele, Peter
(2013)
Insulin is essential for in vitro chondrogenesis of mesenchymal progenitor cells and influences chondrogenesis in a dose-dependent manner.
International Orthopaedics 37 (1), pp. 153-158.
Fulltext not available.
Wurster, Eva-Christina,
Elbakry, Asmaa,
Goepferich, Achim and
Breunig, Miriam
(2013)
Layer-by-layer assembled gold nanoparticles for the delivery of nucleic acids.
In:
Nanotechnology for Nucleic Acid Delivery : Methods and Protocols.
Methods in Molecular Biology, 948.
Humana Press; Springer, Totowa, NJ, pp. 171-182.
ISBN 978-1-62703-139-4 (print), 978-1-627-03140-0 (online).
Fulltext not available.
Pollinger, Klaus,
Hennig, Robert,
Ohlmann, Andreas,
Fuchshofer, R. 
,
Wenzel, Rebecca,
Breunig, Miriam 
,
make_name_string expected hash reference 
,
make_name_string expected hash reference 
and
make_name_string expected hash reference 
(2013)
Ligand-functionalized nanoparticles target endothelial cells in retinal capillaries after systemic application.
Proceedings of the National Academy of Sciences of the United States of America (PNAS) 25, pp. 6115-6120.
Fulltext not available.
Schweizer, Daniel,
Vostiar, Igor,
Heier, Annabelle,
Serno, Tim,
Schoenhammer, Karin,
Jahn, Michael,
Jones, Stewart,
Piequet, Aline,
Beerli, Christian,
Gram, Hermann and
Goepferich, Achim 
(2013)
Pharmacokinetics, biocompatibility and bioavailability of a controlled release monoclonal antibody formulation.
Journal of Controlled Release 172 (3), pp. 975-982.
Fulltext not available.
Miller, Tobias,
Breyer, S.,
van Colen, G.,
Mier, W.,
Haberkorn, U.,
Geissler, S.,
Voss, S.,
Weigandt, Markus and
Goepferich, Achim 
(2013)
Premature drug release of polymeric micelles and its effects on tumor targeting.
International Journal of Pharmaceutics 445 (1-2), pp. 117-124.
Fulltext not available.
Barbič, M.,
Willer, E.A.,
Rothenhöfer, M.,
Heilmann, J.,
Fürst, R. and
Jürgenliemk, G.
(2013)
Spirostanol saponins and esculin from Rusci rhizoma reduce the thrombin-induced hyperpermeability of endothelial cells.
Phytochemistry 90, pp. 106-113.
Fulltext not available.
Susanne Hopf, ,
Monika Bumel, ,
Michael Gruber, 
,
Thomas Bein, ,
Marcus Creutzenberg, ,
Bernhard Graf, and
Michael Pawlik,
(2013)
The Effect of Perchlorate Medication on Point-of-Care Testing.
Clinical Laboratory 59 (01+02/).
Fulltext not available.
Göpferich, Achim
(2013)
To pause a moment.
European Journal of Pharmaceutics and Biopharmaceutics 85 (3), p. 328.
Fulltext not available.
Memminger, Martin,
Keller, Max,
Lopuch, Miroslaw,
Pop, Nathalie,
Bernhardt, Günther,
von Angerer, Erwin and
Buschauer, Armin
(2012)
The Neuropeptide Y Y1 receptor: a diagnostic marker? Expression in MCF-7 breast cancer cells is down-regulated by antiestrogens in vitro and in xenografts.
PLoS ONE 7 (12), e51032.
Löber, Stefan,
Hübner, Harald,
Buschauer, Armin,
Sanna, Fabrizio 
,
Argiolas, Antonio,
Melis, Maria Rosaria and
Gmeiner, Peter 
(2012)
Novel azulene derivatives for the treatment of erectile dysfunction.
Bioorganic & medicinal chemistry letters 22 (23), pp. 7151-7154.
Fulltext not available.
Schlossmann, Jens 
and
Schinner, E.
(2012)
cGMP becomes a drug target.
Naunyn Schmiedeberg´s Archives of Pharmacology 385 (3), pp. 243-252.
Birnkammer, Tobias,
Spickenreither, Anja,
Brunskole, Irena,
Lopuch, Miroslaw,
Kagermeier, Nicole,
Bernhardt, Günther,
Dove, Stefan,
Seifert, Roland,
Elz, Sigurd and
Buschauer, Armin
(2012)
The bivalent ligand approach leads to highly potent and selective acylguanidine-type histamine H2 receptor agonists.
Journal of Medicinal Chemistry 55 (3), pp. 1147-1160.
Fulltext not available.
Bauhuber, Sonja,
Liebl, Renate,
Tomasetti, Luise,
Rachel, Reinhard,
Goepferich, Achim 
and
Breunig, Miriam 
(2012)
A library of strictly linear poly(ethylene glycol)-poly(ethylene imine) diblock coploymers to perform structure-function relationship on non-viral gene carriers.
Journal of Controlled Release 162, pp. 446-455.
Fulltext not available.
Bubik, Martin F.,
Willer, Elisabeth A.,
Bihari, Peter,
Jürgenliemk, Guido,
Ammer, Hermann 
,
Krombach, Fritz,
Zahler, Stefan,
Vollmar, Angelika M. and
Fürst, Robert
(2012)
A novel approach to prevent endothelial hyperpermeability: The Crataegus extract WS® 1442 targets the cAMP/Rap1 pathway.
Journal of Molecular and Cellular Cardiology 52 (1), pp. 196-205.
Fulltext not available.
Schädlich, Andreas,
Hoffmann, Stefan,
Mueller, Thomas,
Caysa, Henrike,
Rose, Cornelia,
Göpferich, Achim 
,
Li, Jun,
Kuntsche, Judith and
Mäder, Karsten
(2012)
Accumulation of nanocarriers in the ovary: A neglected toxicity risk?
Journal of Controlled Release 160 (1), pp. 105-112.
Fulltext not available.
Romanski, Steffen,
Kraus, Birgit,
Guttentag, Miguel,
Schlundt, Waldemar,
Rücker, Hannelore,
Adler, Andreas,
Neudörfl, Jörg-Martin,
Alberto, Roger,
Amslinger, Sabine 
and
Schmalz, Hans-Günther 
(2012)
Acyloxybutadiene tricarbonyl iron complexes as enzyme-triggered CO-releasing molecules (ET-CORMs): a structure–activity relationship study.
Dalton Transactions 41 (45), p. 13862.
Fulltext not available.
Beckers, Thomas,
Mahboobi, Siavosh,
Sellmer, Andreas,
Winkler, Matthias,
Eichhorn, Emerich,
Pongratz, Herwig,
Maier, Thomas,
Ciossek, Thomas,
Baer, Thomas,
Kelter, Gerhard,
Fiebig, Heinz-Herbert and
Schmidt, Mathias
(2012)
Chimerically designed HDAC- and tyrosine kinase inhibitors. A series of erlotinib hybrids as dual-selective inhibitors of EGFR, HER2 and histone deacetylases.
MedChemComm 3 (7), p. 829.
Fulltext not available.
Freischmidt, A.,
Jürgenliemk, G.,
Kraus, B.,
Okpanyi, S.N.,
Müller, J.,
Kelber, O. 
,
Weiser, D. and
Heilmann, J.
(2012)
Contribution of flavonoids and catechol to the reduction of ICAM-1 expression in endothelial cells by a standardised Willow bark extract.
Phytomedicine 19 (3-4), pp. 245-252.
Fulltext not available.
Vo, Hau T.,
Nguyen, Ngoc-Tuyet T.,
Nguyen, Hieu T.,
Do, Khoa Q. 
,
Connolly, Joseph D.,
Maas, Gerhard,
Heilmann, Jörg,
Werz, Udo R.,
Pham, Hung D. and
Nguyen, Lien-Hoa D.
(2012)
Cytotoxic tetraoxygenated xanthones from the bark of Garcinia schomburgkiana.
Phytochemistry Letters 5 (3), pp. 553-557.
Fulltext not available.
Posavec, Damir,
Zabel, Manfred,
Bogner, Udo,
Bernhardt, Günther and
Knör, Günther
(2012)
Functionalized derivatives of 1,4-dimethylnaphthalene as precursors for biomedical applications: synthesis, structures, spectroscopy and photochemical activation in the presence of dioxygen.
Organic & biomolecular chemistry 10 (35), pp. 7062-7069.
Saugspier, Michael,
Dorn, Christoph 
,
Czech, Barbara,
Gehrig, Manfred,
Heilmann, Jörg and
Hellerbrand, Claus 
(2012)
Hop bitter acids inhibit tumorigenicity of hepatocellular carcinoma cells in vitro.
Oncology Reports 28 (4), pp. 1423-1428.
Fulltext not available.
Taha, Hesham,
Dove, Stefan,
Geduhn, Jens,
König, Burkhard 
,
Shen, Yuequan 
,
Tang, Wei-Jen 
and
Seifert, Roland
(2012)
Inhibition of the adenylyl cyclase toxin, edema factor, from Bacillus anthracis by a series of 18 monoand bis-(M)ANT-substituted nucleoside 5′-triphosphates.
Naunyn-Schmiedeberg's Archives of Pharmacology (385), pp. 57-68.
Fulltext not available.
Appl, Heidrun,
Holzammer, Tobias,
Dove, Stefan,
Haen, Ekkehard,
Strasser, Andrea and
Seifert, Roland
(2012)
Interactions of recombinant human histamine H₁R, H₂R, H₃R, and H₄R receptors with 34 antidepressants and antipsychotics.
Naunyn-Schmiedeberg's archives of pharmacology 385 (2), pp. 145-170.
Fulltext not available.
Pollinger, Klaus,
Hennig, Robert,
Breunig, Miriam 
,
Teßmar, Jörg 
,
Ohlmann, Andreas 
,
Tamm, Ernst R. 
,
Witzgall, Ralph 
and
Goepferich, Achim 
(2012)
Kidney Podocytes as Specific Targets for cyclo(RGDfC)-Modified Nanoparticles.
Small 8, pp. 3368-3375.
Fulltext not available.
Elbakry, Asmaa Mohamed,
Wurster, Eva-Christina,
Zaky, Alaa,
Liebl, Renate,
Schindler, Edith,
Bauer-Kreisel, Petra,
Blunk, Torsten,
Rachel, Reinhard,
Goepferich, Achim 
and
Breunig, Miriam 
(2012)
Layer-by-Layer Coated Gold Nanoparticles: Size-Dependent Delivery of DNA into Cells.
Small 8 (24), pp. 3847-3856.
Fulltext not available.
Beckers, Thomas,
Sellmer, Andreas,
Eichhorn, Emerich,
Pongratz, Herwig,
Schächtele, Christoph,
Totzke, Frank,
Kelter, Gerhard,
Krumbach, Rebekka,
Fiebig, Heinz-Herbert,
Böhmer, Frank-D. and
Mahboobi, Siavosh
(2012)
Novel inhibitors of epidermal growth factor receptor: (4-(Arylamino)-7H-pyrrolo[2,3-d]pyrimidin-6-yl)(1H-indol-2-yl)methanones and (1H-indol-2-yl)(4-(phenylamino)thieno[2,3-d]pyrimidin-6-yl)methanones.
Bioorganic & Medicinal Chemistry 20 (1), pp. 125-136.
Fulltext not available.
Ulrich-Merzenich, G.,
Kelber, O. 
,
Koptina, A. 
,
Freischmidt, A.,
Heilmann, J.,
Müller, J.,
Zeitler, H.,
Seidel, M.F.,
Ludwig, M.,
Heinrich, E.U. and
Winterhoff, H.
(2012)
Novel neurological and immunological targets for salicylate-based phytopharmaceuticals and for the anti-depressant imipramine.
Phytomedicine 19 (10), pp. 930-939.
Fulltext not available.
Kees, Martin G.,
Steinke, T.,
Moritz, S.,
Rupprecht, K.,
Paulus, E. M.,
Kees, Frieder K.,
Bucher, M. and
Faerber, L.
(2012)
Omeprazole impairs the absorption of mycophenolate mofetil but not of enteric-coated mycophenolate sodium in healthy volunteers.
Journal of clinical pharmacology 52 (8), pp. 1265-1272.
Fulltext not available.
Justinger, Christoph,
Schilling, Martin K.,
Kees, Martin G.,
Kauffels, Anne,
Hirschmann, Katrin,
Kopp, Berit,
Kees, Frieder K. and
Kollmar, Otto
(2012)
Penetration of moxifloxacin into liver tissue.
International journal of antimicrobial agents 39 (6), pp. 505-509.
Fulltext not available.
Nguyen, Le-Thu T.,
Nguyen, Hieu T.,
Barbič, Matej,
Brunner, Gabi,
Heilmann, Jörg,
Pham, Hung D.,
Nguyen, Duc M. and
Nguyen, Lien-Hoa D.
(2012)
Polyisoprenylated acylphloroglucinols and a polyisoprenylated tetracyclic xanthone from the bark of Calophyllum thorelii.
Tetrahedron Letters 53 (34), pp. 4487-4493.
Fulltext not available.
Ulrich-Merzenich, G.,
Koptina, A. 
,
Kelber, O. 
,
Freischmidt, A.,
Heilmann, J.,
Müller, J.,
Sadeghlar, F.,
Zeitler, H. and
Wagner, H.
(2012)
Prediction of adverse events by in vivo gene expression profiling exemplified for phytopharmaceuticals containing salicylates and the antidepressant imipramine.
Phytomedicine 19 (3-4), pp. 322-329.
Fulltext not available.
Slattery, D.A.,
Naik, R.,
Yen, Y.C.,
Czibere, L.,
Finger, B.,
Mathé, A.A.,
Wegener, G.,
Landgraf, R. and
Neumann, I.D.
(2012)
S.02.02 Neuropeptide S and anxiety.
European Neuropsychopharmacology 22, S31-S32.
Fulltext not available.
Chen, Xinyu,
Zenger, Katharina,
Lupp, Amelie,
Kling, Beata,
Heilmann, Jörg,
Fleck, Christian,
Kraus, Birgit and
Decker, Michael
(2012)
Tacrine-Silibinin Codrug Shows Neuro- and Hepatoprotective Effects in Vitro and Pro-Cognitive and Hepatoprotective Effects in Vivo.
Journal of Medicinal Chemistry 55 (11), pp. 5231-5242.
Fulltext not available.
Heller, Anne,
Brockhoff, Gero and
Goepferich, Achim 
(2012)
Targeting drugs to mitochondria.
European Journal of Pharmaceutics and Biopharmaceutics 82, pp. 1-18.
Fulltext not available.
Schmidt, Jennifer,
Riechers, Alexander,
Stoll, Raphael,
Amann, Thomas,
Fink, Florian,
Spruss, Thilo,
Gronwald, Wolfram,
König, Burkhard 
,
Hellerbrand, Claus and
Bosserhoff, Anja Katrin 
(2012)
Targeting melanoma metastasis and immunosuppression with a new mode of melanoma inhibitory activity (MIA) protein inhibition.
PloS ONE 7 (5), e37941.
Koptina, A,
Kelber, O,
Zeitler, H,
Abdel-Aziz, H,
Ludwig, M,
Heilmann, J,
Freischmidt, A,
Wagner, H and
Ulrich-Merzenich, G
(2012)
Targeting of LOX-1 by willow bark, its etoh-fraction and by the antidepressant imipramine.
Planta Medica 78 (11).
Fulltext not available.
Seifert, S,
Kiesselbach, C,
Kopeinig, B,
Bauer, R,
Gessner, A and
Haunschild, J
(2012)
The Novel Sinupret® dry extract BNO 1011 inhibits paw oedema development in vivo and inflammatory mediator release in vitro.
Planta Medica 78 (11).
Fulltext not available.
Jaumann, Mirko,
Dettling, Juliane,
Gubelt, Martin,
Zimmermann, Ulrike,
Gerling, Andrea,
Paquet-Durand, François 
,
Feil, Susanne 
,
Wolpert, Stephan,
Franz, Christoph,
Varakina, Ksenya,
Xiong, Hao,
Brandt, Niels,
Kuhn, Stephanie,
Geisler, Hyun-Soon,
Rohbock, Karin,
Ruth, Peter,
Schlossmann, Jens 
,
Hütter, Joachim,
Sandner, Peter,
Feil, Robert 
,
Engel, Jutta,
Knipper, Marlies and
Rüttiger, Lukas
(2012)
cGMP-Prkg1 signaling and Pde5 inhibition shelter cochlear hair cells and hearing function.
Nature Medicine 18 (2), pp. 252-259.
Fulltext not available.
Braun, Stephan,
Botzki, Alexander 
,
Salmen, Sunnhild,
Textor, Christian,
Bernhardt, Günther,
Dove, Stefan and
Buschauer, Armin
(2011)
Design of benzimidazole- and benzoxazole-2-thione derivatives as inhibitors of bacterial hyaluronan lyase.
European Journal of Medicinal Chemistry 46 (9), pp. 4419-4429.
Fulltext not available.
Hübner, Melanie,
Dixit, A.,
Mou, T.-C.,
Lushington, Gerald H.,
Pinto, Cibele S.,
Gille, A. 
,
Geduhn, Jens,
König, Burkhard 
,
Sprang, S. R. and
Seifert, Roland
(2011)
Structural Basis for the High-Affinity Inhibition of Mammalian Membranous Adenylyl Cyclase by 2`,3`-O-(N-Methylanthraniloyl)-Inosine 5`-Triphosphate.
Molecular Pharmacology 80 (1), pp. 87-96.
Fulltext not available.
Pluym, Nikola,
Brennauer, Albert,
Keller, Max,
Ziemek, Ralf,
Pop, Nathalie,
Bernhardt, Günther and
Buschauer, Armin
(2011)
Application of the guanidine – acylguanidine bioisosteric approach to argininamide-type NPY Y2 receptor antagonists.
ChemMedChem 6 (9), pp. 1727-1738.
Fulltext not available.
Klein, Matthias S. 
,
Dorn, Christoph,
Saugspier, Michael Sebastian,
Hellerbrand, Claus,
Oefner, Peter J. 
and
Gronwald, Wolfram
(2011)
Discrimination of steatosis and NASH in mice using nuclear magnetic resonance spectroscopy.
Metabolomics 7 (2), pp. 237-246.
Fulltext not available.
Keller, Max,
Erdmann, Daniela,
Teng, Shangjun,
Pop, Nathalie 
,
Pluym, Nikola,
Bernhardt, Günther and
Buschauer, Armin
(2011)
Red-fluorescent argininamide-type NPY Y(1) receptor antagonists as pharmacological tools.
Bioorganic & Medicinal Chemistry 19 (9), pp. 2859-2878.
Fulltext not available.
Kellermann, K.,
Dertinger, N.,
Blobner, M.,
Kees, Frieder,
Kochs, E. F. and
Jungwirt, B.
(2011)
Perioperative moxifloxacin treatment in rats subjected to deep hypothermic circulatory arrest: reduction in cerebral inflammation but without improvement in cognitive performance.
Journal of Thoracic and Cardiovascular Surgery 141 (3), pp. 796-802.
Fulltext not available.
Schnell, David,
Brunskole, Irena,
Ladova, Katerina,
Schneider, Erich H. 
,
Igel, Patrick,
Dove, Stefan,
Buschauer, Armin and
Seifert, Roland
(2011)
Expression and functional properties of canine, rat and murine histamine H4-receptors in Sf9 insect cells.
Naunyn-Schmiedeberg's Archives of Pharmacology 383 (5), pp. 457-470.
Fulltext not available.
Seifert, Roland,
Schneider, Erich H. 
,
Dove, Stefan,
Brunskole, Irena,
Neumann, Detlef 
,
Strasser, Andrea and
Buschauer, Armin
(2011)
Paradoxical stimulatory effects of the “standard” histamine H4-receptor antagonist JNJ7777120: The H4-receptor joins the club of 7TM receptors exhibiting functional selectivity.
Molecular Pharmacology 79 (4), pp. 631-638.
Fulltext not available.
Gäbele, Erwin,
Dostert, Karin,
Dorn, Christoph 
,
Patsenker, Eleonora,
Stickel, Felix and
Hellerbrand, Claus
(2011)
A New Model of Interactive Effects of Alcohol and High-Fat Diet on Hepatic Fibrosis.
Alcoholism: Clinical and Experimental Research 35 (7), pp. 1361-1367.
Fulltext not available.
Wanninger, Josef,
Neumeier, Markus,
Bauer, Sabrina,
Weiss, Thomas S. 
,
Eisinger, Kristina,
Walter, Roland,
Dorn, Christoph 
,
Hellerbrand, Claus,
Schäffler, Andreas and
Buechler, Christa
(2011)
Adiponectin induces the transforming growth factor decoy receptor BAMBI in human hepatocytes.
FEBS Letters 585 (9), pp. 1338-1344.
Fulltext not available.
Kelber, O,
Okpanyi, SN,
Freischmidt, A,
Heinrich, EU,
Müller, J,
Heilmann, J,
Ulrich Merzenich, G and
Weiser, D
(2011)
Antidepressant mechanisms of action of willow bark extract STW 33-I.
Planta Medica 77 (12).
Fulltext not available.
Kees, Frieder,
Jehkul, Andreas,
Bucher, Michael,
Mair, Georg,
Kiermaier, Josef and
Grobecker, Horst
(2011)
Bioavailability of Opipramol from a Film-coated Tablet, a Sugar-coated Tablet and an Aqueous Solution in Healthy Volunteers.
Arzneimittelforschung 53 (02), pp. 87-92.
Fulltext not available.
Gonenc, T.,
Argyropoulou, C.,
Erdogan, T.,
Gousiadou, C.,
Juergenliemk, G.,
Kıvçak, B. and
Skaltsa, H.
(2011)
Chemical constituents from Anthemis wiedemanniana Fisch. & Mey.
Biochemical Systematics and Ecology 39 (1), pp. 51-55.
Fulltext not available.
Ulrich Merzenich, G,
Koptina, A,
Kelber, O,
Freischmidt, A,
Heilmann, J,
Müller, J,
Zeitler, H,
Panek, D and
Winterhoff, H
(2011)
Comparative analysis of gene expression profiles from rats treated with a standardized willow bark preparation, its salicin rich ethanol fraction and imipramine for toxicological endpoints.
Planta Medica 77 (12).
Fulltext not available.
Scheruebl, R,
Orland, A,
Demirci, B,
Knoess, W,
Başer, KHC,
Franz, G and
Heilmann, J
(2011)
Comprehensive Analysis of Artemisiae scopariae herba from different growing areas.
Planta Medica 77 (12).
Fulltext not available.
Rossbach, K.,
Nassenstein, C.,
Gschwandtner, M. 
,
Schnell, D.,
Sander, K.,
Seifert, R.,
Stark, H. 
,
Kietzmann, M. and
Bäumer, W.
(2011)
Histamine H1, H3 and H4 receptors are involved in pruritus.
Neuroscience 190, pp. 89-102.
Fulltext not available.
Schaedlich, A.,
Rose, C.,
Kuntsche, J.,
Caysa, H.,
Mueller, T.,
Goepferich, Achim 
and
Maeder, K.
(2011)
How Stealthy are PEG-PLA Nanoparticles? An NIR In Vivo Study Combined with Detailed Size Measurements.
Pharmaceutical Research 28 (8), pp. 1995-2007.
Fulltext not available.
Ertl, C.,
Lukowski, R.,
Sigl, K.,
Schlossmann, Jens 
,
Hofmann, F. and
Wegener, Jörg W.
(2011)
Kinetics of relaxation by cGMP/cGKI signaling in fundus smooth muscle.
Eur J Pharmacol 670 (1), pp. 266-271.
Fulltext not available.
Oberprieler, Christoph,
Hartl, Sabine,
Schauer, Kerstin,
Meister, Jörg and
Heilmann, Jörg
(2011)
Morphological, phytochemical and genetic variation in mixed stands and a hybrid swarm of Senecio germanicus and S. ovatus (Compositae, Senecioneae).
Plant Systematics and Evolution 293 (1-4), pp. 177-191.
Fulltext not available.
Macabeo, Allan Patrick G.,
Vidar, Warren S.,
Chen, Xinyu,
Decker, Michael,
Heilmann, Jörg,
Wan, Baojie,
Franzblau, Scott G. 
,
Galvez, Elano V.,
Aguinaldo, Ma. Alicia M. and
Cordell, Geoffrey A.
(2011)
Mycobacterium tuberculosis and cholinesterase inhibitors from Voacanga globosa.
European Journal of Medicinal Chemistry 46 (7), pp. 3118-3123.
Fulltext not available.
Ferstl, Matthias,
Strasser, Andrea,
Wittmann, Hans-Joachim,
Drechsler, Markus 
,
Rischer, M.,
Engl, J. and
Goepferich, Achim 
(2011)
Nanofibres Resulating from Cooperative Electrostatic and Hydrophobic Interactions between Peptides and Polyelectrolytes of Opposite Charge.
Langmuir 27, pp. 14450-14459.
Fulltext not available.
Henkel, Janin,
Gärtner, Daniela,
Dorn, Christoph 
,
Hellerbrand, Claus,
Schanze, Nancy,
Elz, Sheila R. and
Püschel, Gerhard P.
(2011)
Oncostatin M produced in Kupffer cells in response to PGE2: possible contributor to hepatic insulin resistance and steatosis.
Laboratory Investigation 91 (7), pp. 1107-1117.
Fulltext not available.
Posavec, Damir,
Dorsch, Andre,
Bogner, Udo,
Bernhardt, Guenther and
Nagl, Stefan 
(2011)
Polyvinyl butyral nanobeads: preparation, characterization, biocompatibility and cancer cell uptake.
Microchimica acta 173 (3-4), pp. 391-399.
Fulltext not available.
Patsenker, Eleonora,
Schneider, Vreni,
Ledermann, Monika,
Saegesser, Hans,
Dorn, Christoph 
,
Hellerbrand, Claus and
Stickel, Felix
(2011)
Potent antifibrotic activity of mTOR inhibitors sirolimus and everolimus but not of cyclosporine A and tacrolimus in experimental liver fibrosis.
Journal of Hepatology 55 (2), pp. 388-398.
Fulltext not available.
Ochoa Puentes, Cristian,
Höcherl, Peter,
Kühnle, Matthias,
Bauer, Stefanie,
Kürger, Kira,
Bernhardt, Günther,
Buschauer, Armin and
König, Burkhard 
(2011)
Solid phase synthesis of tariquidar-related modulators of ABC transporters preferring breast cancer resistance protein (ABCG2).
Bioorganic & Medicinal Chemistry Letters 21 (12), pp. 3654-3657.
Fulltext not available.
Bauer, Sabrina,
Wanninger, Josef,
Schmidhofer, Sandra,
Weigert, Johanna,
Neumeier, Markus,
Dorn, Christoph 
,
Hellerbrand, Claus,
Zimara, Nicole,
Schäffler, Andreas,
Aslanidis, Charalampos and
Buechler, Christa
(2011)
Sterol Regulatory Element-Binding Protein 2 (SREBP2) Activation after Excess Triglyceride Storage Induces Chemerin in Hypertrophic Adipocytes.
Endocrinology 152 (1), pp. 26-35.
Fulltext not available.
Werder, A.,
Mayr, M.,
Schneider, G.,
Oesterle, D.,
Fritsch, R. M.,
Seidler, B.,
Schlossmann, Jens 
,
Hofmann, F.,
Schemann, M. 
,
Allescher, H. D.,
Schmid, R. M. and
Saur, D. 
(2011)
Truncated IRAG variants modulate cGMP-mediated inhibition of human colonic smooth muscle cell contraction.
American Journal of Physiology - Cell Physiology : Am J Physiol Cell Physiol 301 (6), C1445-1457.
Fulltext not available.
Schaedlich, A.,
Caysa, H.,
Mueller, T.,
Tenambergen, F.,
Rose, Cornelia,
Goepferich, Achim 
,
Kuntsche, J. and
Maeder, K.
(2011)
Tumor Accumulation of NIR Fluorescent PEG PLA Nanoparticles: Impact of Particle Size and Human Xenograft Tumor Model.
ACS Nano 5, pp. 8710-8720.
Fulltext not available.
Wolff, Horst,
Motyl, Magdalena,
Hellerbrand, Claus,
Heilmann, Jörg and
Kraus, Birgit
(2011)
Xanthohumol Uptake and Intracellular Kinetics in Hepatocytes, Hepatic Stellate Cells, and Intestinal Cells.
Journal of Agricultural and Food Chemistry 59 (24), pp. 12893-12901.
Fulltext not available.
Igel, Patrick,
Dove, Stefan and
Buschauer, Armin
(2010)
Histamine H4 receptor agonists.
Bioorganic & Medicinal Chemistry Letters 20 (24), pp. 7191-7199.
Fulltext not available.
Dayoub, Rania 
,
Wagner, Hannah,
Bataille, Frauke,
Stöltzing, Oliver,
Spruss, Thilo,
Buechler, Christa,
Schlitt, Hans-Jürgen and
Weiss, Thomas S. 
(2010)
Liver Regeneration Associated Protein (ALR) Exhibits Antimetastatic Potential in Hepatocellular Carcinoma.
Molecular Medicine 17, pp. 221-228.
Modrow, Susanne,
Wenzel, J. J. 
,
Schimanski, S.,
Schwarzbeck, J.,
Rothe, U.,
Oldenburg, J.,
Jilg, W. and
Eis-Hübinger, A. M.
(2010)
Prevalence of nucleic acid sequences specific for human parvoviruses, hepatitis A and hepatitis E viruses in coagulation factor concentrates.
Vox sanguinis.
Fulltext restricted.
Mathar, I.,
Vennekens, R.,
Meissner, M.,
Kees, Frieder K.,
Van der Mieren, G. and
Camacho Londono, J.
(2010)
Increased catecholamine secretion contributes to hypertension in TRPM4-deficient mice.
The Journal of Clinical Investigation 120 (9), pp. 3267-3279.
Fulltext not available.
Desch, Matthias,
Schinner, Elisabeth,
Kees, Frieder K.,
Hofmann, F.,
Seifert, Roland and
Schlossmann, Jens
(2010)
Cyclic cytidine 3´,5´-monophosphate (cCMP) signals via cGMP kinase I.
FEBS Letters 584 (18), pp. 3979-3984.
Fulltext not available.
Kirovski, Georgi,
Gäbele, Erwin,
Dorn, Christoph 
,
Moleda, Lukas,
Niessen, Christoph,
Weiss, Thomas S. 
,
Wobser, Hella,
Schacherer, Doris,
Buechler, Christa 
,
Wasmuth, Hermann E. and
Hellerbrand, Claus
(2010)
Hepatic steatosis causes induction of the chemokine RANTES in the absence of significant hepatic inflammation.
International Journal of Clinical and Experimental Pathology 3 (7), pp. 675-680.
Desch, Matthias,
Sigl, K.,
Hieke, Bernhard,
Salb, Katharina,
Kees, F.,
Bernhard, D.,
make_name_string expected hash reference,
make_name_string expected hash reference,
make_name_string expected hash reference,
make_name_string expected hash reference 
,
make_name_string expected hash reference 
,
make_name_string expected hash reference,
make_name_string expected hash reference,
make_name_string expected hash reference and
make_name_string expected hash reference 
(2010)
IRAG determines nitric oxide- and atrial natriuretic peptide-mediated smooth muscle relaxation.
Cardiovascular Research 86 (3), pp. 496-505.
Fulltext not available.
Ghorai, Prasanta,
Kraus, Anja,
Birnkammer, Tobias,
Geyer, Roland,
Bernhardt, Günther,
Dove, Stefan,
Seifert, Roland,
Elz, Sigurd and
Buschauer, Armin
(2010)
Chiral N(G)-acylated hetarylpropylguanidine-type histamine H2 receptor agonists do not show significant stereoselectivity.
Bioorganic & Medicinal Chemistry Letters 20 (10), pp. 3173-3176.
Fulltext not available.
Dorn, Christoph 
,
Riener, Marc-Oliver,
Kirovski, Georgi,
Saugspier, Michael,
Steib, Kathrin,
Weiss, Thomas S. 
,
Gäbele, Erwin,
Kristiansen, Glen,
Hartmann, Arndt and
Hellerbrand, Claus
(2010)
Expression of fatty acid synthase in nonalcoholic fatty liver disease.
International Journal of Clinical and Experimental Pathology 3 (5), pp. 505-514.
Amann, Thomas,
Bataille, Frauke,
Spruss, Thilo,
Dettmer, Katja 
,
Wild, Peter J.,
Liedtke, Christian 
,
Mühlbauer, Marcus,
Kiefer, Paul,
Oefner, Peter J. 
,
Trautwein, Christian,
Bosserhoff, Anja-Katrin 
and
Hellerbrand, Claus
(2010)
Reduced expression of fibroblast growth factor receptor 2IIIb in hepatocellular carcinoma induces a more aggressive growth.
The American journal of pathology 176 (3), pp. 1433-42.
Fulltext not available.
Dietl, Katrin,
Renner, Kathrin,
Dettmer, Katja 
,
Timischl, Birgit,
Eberhart, Karin,
Dorn, Christoph,
Hellerbrand, Claus,
Kastenberger, Michael,
Kunz-Schughart, Leoni A.,
Oefner, Peter J. 
,
Andreesen, Reinhard,
Gottfried, Eva and
Kreutz, Marina
(2010)
Lactic acid and acidification inhibit TNF secretion and glycolysis of human monocytes.
Journal of immunology 184 (3), pp. 1200-1209.
Fulltext not available.
Feizlmayr, E,
Sutor, S,
Stinglmayr, I,
Kunert, O,
Heilmann, J and
Bauer, R
(2010)
Cannabinoid receptor activity of polyacetylenes and polyenes from Echinacea pallida.
Planta Medica 76 (12).
Fulltext not available.
Uecker, Andrea,
Sicker, Marit,
Beckers, Thomas,
Mahboobi, Siavosh,
Hägerstrand, Daniel 
,
Östman, Arne and
Böhmer, Frank-D.
(2010)
Chimeric tyrosine kinase-HDAC inhibitors as antiproliferative agents.
Anti-Cancer Drugs 21 (8), pp. 759-765.
Fulltext not available.
Göttle, Martin,
Dove, Stefan,
Kees, Frieder K.,
Schlossmann, Jens 
,
Geduhn, Jens,
König, Burkhard 
,
Shen, Y.,
Tang, W. J. 
,
Kaever, V. and
Seifert, Roland
(2010)
Citidylyl and uridylyl cyclase activity of bacillus anthracis edema factor and Bordetella pertussis CyaA.
Biochemistry 49, pp. 5494-5503.
Fulltext not available.
Kleinmaier, Roland,
Igel, Patrick,
Keller, Max,
Buschauer, Armin and
Gschwind, Ruth M. 
(2010)
Conformations, Conformational Preferences, and Conformational Exchange of N'-Substituted N-Acylguanidines: Intermolecular Interactions Hold the Key.
J. Am. Chem. Soc. 132 (32), pp. 11223-11233.
Fulltext not available.
Desch, Matthias,
Schinner, Elisabeth,
Kees, Frieder,
Hofmann, Franz,
Seifert, Roland and
Schlossmann, Jens 
(2010)
Cyclic cytidine 3′,5′‐monophosphate (cCMP) signals via cGMP kinase I.
FEBS Letters 584 (18), pp. 3979-3984.
Fulltext not available.
Shwe, Htay Htay,
Aye, Mye,
Sein, Myint Myint,
Htay, Khin Than,
Kreitmeier, Peter,
Gertsch, Jürg,
Reiser, Oliver 
and
Heilmann, Jörg
(2010)
Cytotoxic Steroidal Saponins from the Rhizomes of Tacca integrifolia.
Chemistry & Biodiversity 7 (3), pp. 610-622.
Fulltext not available.
Schmidt, Florian,
Schmidt, J.,
Riechers, A.,
Haase, S.,
Bosserhoff, Anja-Katrin,
Heilmann, J. and
König, Burkhard 
(2010)
DNA Staining in Agarose Gels with Zn2+ -Cyclen-Pyrene.
Nucleosides, Nucleotides & Nucleic Acids (29), pp. 748-759.
Fulltext not available.
Sander, Kerstin,
Kottke, Tim,
Hoffend, Claas,
Walter, Miriam,
Weizel, Lilia,
Camelin, Jean-Claude,
Ligneau, Xavier,
Schneider, Erich H. 
,
Seifert, Roland,
Schwartz, Jean-Charles and
Stark, Holger 
(2010)
First Metal-Containing Histamine H3 Receptor Ligands.
Organic Letters 12 (11), pp. 2578-2581.
Fulltext not available.
Brandl, Ferdinand,
Kastner, Fritz,
Gschwind, R. M. 
,
Blunk, Torsten,
Teßmar, Jörg 
and
Göpferich, Achim 
(2010)
Hydrogel-based drug delivery systems: Comparison of drug diffusivity and release kinetics.
Journal of Controlled Release 142 (2), pp. 221-228.
Fulltext not available.
Desch, M.,
Sigl, K.,
Hieke, B.,
Salb, Katharina,
Kees, Frieder,
Bernhard, D.,
Jochim, A.,
Spiessberger, B.,
Höcherl, K.,
Feil, R. 
,
Lukowski, R. 
,
Wegener, Jörg W.,
Hofmann, F.,
Schlossmann, Jens and
make_name_string expected hash reference 
(2010)
IRAG determines NO- and ANP-mediated smooth muscle relaxation.
Cardiovascular Research 86 (3), pp. 496-505.
Fulltext not available.
Mathar, Ilka,
Vennekens, Rudi 
,
Meissner, Marcel,
Kees, Frieder,
Van der Mieren, Gerry,
Camacho Londoño, Juan E.,
Uhl, Sebastian,
Voets, Thomas 
,
Hummel, Björn,
van den Bergh, An,
Herijgers, Paul 
,
Nilius, Bernd,
Flockerzi, Veit,
Schweda, Frank and
Freichel, Marc
(2010)
Increased catecholamine secretion contributes to hypertension in TRPM4-deficient mice.
Journal of Clinical Investigation 120 (9), pp. 3267-3279.
Fulltext not available.
Mahboobi, Siavosh,
Sellmer, Andreas,
Winkler, Matthias,
Eichhorn, Emerich,
Pongratz, Herwig,
Ciossek, Thomas,
Baer, Thomas,
Maier, Thomas and
Beckers, Thomas
(2010)
Novel Chimeric Histone Deacetylase Inhibitors: A Series of Lapatinib Hybrides as Potent Inhibitors of Epidermal Growth Factor Receptor (EGFR), Human Epidermal Growth Factor Receptor 2 (HER2), and Histone Deacetylase Activity.
Journal of Medicinal Chemistry 53 (24), pp. 8546-8555.
Fulltext not available.
Freischmidt, A,
Jürgenliemk, G,
Kraus, B,
Okpanyi, S,
Müller, J,
Kelber, O,
Weiser, D and
Heilmann, J
(2010)
Phenolic compounds in the ethyl acetate fraction of a standardized willow bark extract.
Planta Medica 76 (12).
Fulltext not available.
Jandt, Enrico,
Mutschke, Oliver,
Mahboobi, Siavosh,
Uecker, Andrea,
Platz, Ronny,
Berndt, Alexander,
Böhmer, Frank-D.,
Figulla, Hans R. and
Werner, Gerald S.
(2010)
Stent-based release of a selective PDGF-receptor blocker from the bis-indolylmethanon class inhibits restenosis in the rabbit animal model.
Vascular Pharmacology 52 (1-2), pp. 55-62.
Fulltext not available.
Holzhauser, C.,
Berndl, Sina,
Menacher, Florian,
Breunig, Miriam 
,
Göpferich, Achim 
and
Wagenknecht, Hans-Achim
(2010)
Synthesis and Optical Properties of Cyanine Dyes as Fluorescent DNA Base Substitutions for Live Cell Imaging.
European Journal of Organic Chemistry (7), pp. 1239-1248.
Fulltext not available.
Emmrich, Thomas,
El-Tayeb, Ali,
Taha, Hesham,
Seifert, Roland,
Müller, Christa E. and
Link, Andreas 
(2010)
Synthesis of a hydrolytically stable, fluorescent-labeled ATP analog as a tool for probing adenylyl cyclases.
Bioorganic & Medicinal Chemistry Letters 20 (1), pp. 232-235.
Fulltext not available.
Korte, G.,
Dreiseitel, A.,
Schreier, P.,
Oehme, A.,
Locher, S.,
Geiger, S.,
Heilmann, J. and
Sand, P.G. 
(2010)
Tea catechins’ affinity for human cannabinoid receptors.
Phytomedicine 17 (1), pp. 19-22.
Fulltext not available.
Fürst, R,
Bubik, M,
Bihari, P,
Jürgenliemk, G,
Ammer, H,
Krombach, F,
Zahler, S and
Vollmar, A
(2010)
The hawthorn special extract WS® 1442 protects against endothelial barrier dysfunction – elucidation of the underlying molecular mechanisms.
Planta Medica 76 (12).
Fulltext not available.
Dorn, Christoph,
Kraus, Birgit,
Motyl, Magdalena,
Weiss, Thomas S. 
,
Gehrig, Manfred,
Schoelmerich, Juergen,
Heilmann, Jörg and
Hellerbrand, Claus
(2010)
Xanthohumol, a chalcon derived from hops, inhibits hepatic inflammation and fibrosis.
Molecular nutrition & food research 54 (Suppl.), S205-S213.
Fulltext not available.
Dorn, Christoph,
Weiss, Thomas S. 
,
Heilmann, Jörg and
Hellerbrand, Claus
(2010)
Xanthohumol, a prenylated chalcone derived from hops, inhibits proliferation, migration and interleukin-8 expression of hepatocellular carcinoma cells.
International journal of oncology 36 (2), pp. 435-441.
Fulltext not available.
Igel, Patrick,
Geyer, Roland,
Straßer, Andrea,
Dove, Stefan,
Seifert, Roland and
Buschauer, Armin
(2009)
Synthesis and structure-activity relationships of cyanoguanidine-type and structurally related histamine H(4) receptor agonists.
Journal of Medicinal Chemistry 52 (20), pp. 6297-6313.
Fulltext not available.
Igel, Patrick,
Schneider, Erich 
,
Schnell, David,
Elz, Sigurd,
Seifert, Roland and
Buschauer, Armin
(2009)
N(G)-Acylated imidazolylpropylguanidines as potent histamine H4 receptor agonists: selectivity by variation of the N(G)-substituent.
Journal of Medicinal Chemistry 52 (8), pp. 2623-2627.
Fulltext not available.
Kraus, Anja,
Ghorai, Prasanta,
Birnkammer, Tobias,
Schnell, David,
Elz, Sigurd,
Seifert, Roland,
Dove, Stefan,
Bernhardt, Günther and
Buschauer, Armin
(2009)
N(G)-Acylated aminothiazolylpropylguanidines as potent and selective histamine H2 receptor agonists.
ChemMedChem 4 (2), pp. 232-240.
Fulltext not available.
Igel, Patrick,
Schnell, David,
Bernhardt, Günther,
Seifert, Roland and
Buschauer, Armin
(2009)
Tritium-labeled N1-[3-(1H-imidazol-4-yl)propyl]-N2-propionylguanidine ([3H]UR-PI294), a high affinity histamine H3 and H4 receptor radioligand.
ChemMedChem 4 (2), pp. 225-231.
Fulltext not available.
Kühnle, Matthias,
Egger, Michael,
Müller, Christine,
Mahringer, Anne,
Bernhardt, Günther,
Fricker, Gert 
,
König, Burkhard 
and
Buschauer, Armin
(2009)
Potent and selective inhibitors of breast cancer resistance protein (ABCG2) derived from the p-glycoprotein (ABCB1) modulator tariquidar.
Journal of Medicinal Chemistry 52 (4), pp. 1190-1197.
Fulltext not available.
Sander, Kerstin,
Kottke, Tim,
Tanrikulu, Yusuf,
Proschak, Ewgenij,
Weizel, Lilia,
Schneider, Erich H. 
,
Seifert, Roland,
Schneider, Gisbert 
and
Stark, Holger 
(2009)
2,4-Diaminopyrimidines as histamine H4 receptor ligands—Scaffold optimization and pharmacological characterization.
Bioorganic & Medicinal Chemistry 17 (20), pp. 7186-7196.
Fulltext not available.
Romagnoli, Romeo,
Baraldi, Pier Giovanni,
Carrion, Maria Dora 
,
Cruz-Lopez, Olga,
Lopez Cara, Carlota,
Basso, Giuseppe,
Viola, Giampietro 
,
Khedr, Mohammed 
,
Balzarini, Jan,
Mahboobi, Siavosh,
Sellmer, Andreas,
Brancale, Andrea 
and
Hamel, Ernest
(2009)
2-Arylamino-4-Amino-5-Aroylthiazoles. “One-Pot” Synthesis and Biological Evaluation of a New Class of Inhibitors of Tubulin Polymerization.
Journal of Medicinal Chemistry 52 (17), pp. 5551-5555.
Fulltext not available.
Amann, Thomas,
Bataille, Frauke,
Spruss, Thilo,
Mühlbauer, Marcus,
Gäbele, Erwin,
Schölmerich, Jürgen,
Kiefer, Paul,
Bosserhoff, Anja‐Katrin 
and
Hellerbrand, Claus
(2009)
Activated hepatic stellate cells promote tumorigenicity of hepatocellular carcinoma.
Cancer Science 100 (4), pp. 646-653.
Fulltext not available.
Hartkorn, Andreas,
Hoffmann, Florian,
Ajamieh, Hussam,
Vogel, Susanne,
Heilmann, Jörg,
Gerbes, Alexander L.,
Vollmar, Angelika M. and
Zahler, Stefan 
(2009)
Antioxidant Effects of Xanthohumol and Functional Impact on Hepatic Ischemia−Reperfusion Injury.
Journal of Natural Products 72 (10), pp. 1741-1747.
Fulltext not available.
Weiser, Barbara,
Sommer, Florian,
Neubauer, M.,
Seitz, Anna Katharina,
Teßmar, Jörg 
,
Göpferich, Achim 
and
Blunk, Torsten
(2009)
Ascorbic Acid Enhances Adipogenesis of Bone Marrow-Derived Mesenchymal Stromal Cells.
Cells Tissues Organs 189 (6), pp. 373-381.
Fulltext not available.
Rupprecht, Korbinian,
Schmidt, Christoph,
Raspé, Anne,
Schweda, Frank,
Shipkova, Maria,
Fischer, Wolfgang,
Bucher, Michael,
Kees, Frieder and
Faerber, Lothar
(2009)
Bioavailability of Mycophenolate Mofetil and Enteric‐Coated Mycophenolate Sodium Is Differentially Affected by Pantoprazole in Healthy Volunteers.
The Journal of Clinical Pharmacology 49 (10), pp. 1196-1201.
Fulltext not available.
Heidel, Florian,
Lipka, Daniel B.,
Mirea, Fian K.,
Mahboobi, Siavosh,
Grundler, Rebekka,
Kancha, Rama K.,
Duyster, Justus,
Naumann, Michael 
,
Huber, Christoph,
Böhmer, Frank D. and
Fischer, Thomas
(2009)
Bis(1H‐indol‐2‐yl)methanones are effective inhibitors of FLT3‐ITD tyrosine kinase and partially overcome resistance to PKC412A in vitro.
British Journal of Haematology 144 (6), pp. 865-874.
Fulltext not available.
Göttle, Martin,
Geduhn, Jens,
König, Burkhard 
,
Gille, Andreas 
,
Höcherl, Klaus and
Seifert, Roland
(2009)
Characterization of Mouse Heart Adenylyl Cyclase.
Journal of Pharmacology and Experimental Therapeutics 329 (3), pp. 1156-1165.
Fulltext not available.
Mahboobi, Siavosh,
Dove, Stefan,
Sellmer, Andreas,
Winkler, Matthias,
Eichhorn, Emerich,
Pongratz, Herwig,
Ciossek, Thomas,
Baer, Thomas,
Maier, Thomas and
Beckers, Thomas
(2009)
Design of chimeric histone deacetylase- and tyrosine kinase-inhibitors: a series of imatinib hybrides as potent inhibitors of wild-type and mutant BCR-ABL, PDGF-Rbeta, and histone deacetylases.
Journal of medicinal chemistry 52 (8), pp. 2265-79.
Fulltext not available.
Suryanarayana, Srividya,
Göttle, Martin,
Hübner, Melanie,
Gille, Andreas 
,
Mou, Tung-Chung,
Sprang, Stephen R.,
Richter, Mark and
Seifert, Roland
(2009)
Differential Inhibition of Various Adenylyl Cyclase Isoforms and Soluble Guanylyl Cyclase by 2′,3′-O-(2,4,6-Trinitrophenyl)-Substituted Nucleoside 5′-Triphosphates.
Journal of Pharmacology and Experimental Therapeutics 330 (3), pp. 687-695.
Fulltext not available.
Pinto, Cibele,
Hübner, Melanie,
Gille, Andreas 
,
Richter, Mark,
Mou, Tung-Chung,
Sprang, Stephen R. and
Seifert, Roland
(2009)
Differential interactions of the catalytic subunits of adenylyl cyclase with forskolin analogs.
Biochemical Pharmacology 78 (1), pp. 62-69.
Fulltext not available.
Massoumi, Ramin,
Kuphal, Silke,
Hellerbrand, Claus,
Haas, Bodo 
,
Wild, Peter,
Spruss, Thilo,
Pfeifer, Alexander,
Fässler, Reinhard and
Bosserhoff, Anja K. 
(2009)
Down-regulation of CYLD expression by Snail promotes tumor progression in malignant melanoma.
Journal of Experimental Medicine 206 (1), pp. 221-232.
Fulltext not available.
Osten, Larissa,
Kubitza, Marion,
Gallagher, Anna Rachel,
Kastner, Jürgen,
Olbrich, Heike,
Vries, Uwe,
Kees, Frieder,
Lelongt, Brigitte,
Somlo, Stefan,
Omran, Heymut and
Witzgall, Ralph 
(2009)
Doxycycline accelerates renal cyst growth and fibrosis in the pcy/pcy mouse model of type 3 nephronophthisis, a form of recessive polycystic kidney disease.
Histochemistry and Cell Biology 132 (2), pp. 199-210.
Fulltext not available.
Beule, Achim G. 
,
Steinmeier, Elke,
Kaftan, Holger,
Biebler, Karl-Ernst,
Gopferich, Achim 
,
Wolf, Eduard and
Hosemann, Werner
(2009)
Effects of a Dexamethasone-Releasing Stent on Osteoneogenesis in a Rabbit Model.
American Journal of Rhinology & Allergy 23 (4), pp. 433-436.
Fulltext not available.
Beule, A. G.,
Steinmeier, E.,
Kaftan, H.,
Biebler, K.-E.,
Göpferich, Achim,
Wolf, Eva and
Hosemann, W.
(2009)
Effects of a dexamethasone-releasing stent on osteoneogenesis in a rabbit model.
American journal of rhinology & allergy 23 (4), pp. 433-436.
Fulltext not available.
Sommer, Florian,
Brandl, Ferdinand,
Weiser, Barbara,
Teßmar, Jörg 
,
Blunk, Torsten and
Göpferich, Achim 
(2009)
FACS as useful tool to study distinct hyalocyte populations.
Experimental Eye Research 88 (5), pp. 995-999.
Fulltext not available.
Šlapetová, Tereza,
Šmejkal, Karel 
,
Innocenti, Gabbriella,
Dall’Acqua, Stefano,
Heilmann, Jörg,
Babula, Petr,
Hamzová, Eva and
Žemlička, Milan
(2009)
Glycosylated nervogenic acid derivatives from Liparis condylobulbon (Reichb.f.) leaves.
Carbohydrate Research 344 (13), pp. 1770-1774.
Fulltext not available.
Tanrikulu, Yusuf,
Proschak, Ewgenij,
Werner, Tim,
Geppert, Tim,
Todoroff, Nickolay,
Klenner, Alexander,
Kottke, Tim,
Sander, Kerstin,
Schneider, Erich 
,
Seifert, Roland,
Stark, Holger 
,
Clark, Timothy 
and
Schneider, Gisbert 
(2009)
Homology Model Adjustment and Ligand Screening with a Pseudoreceptor of the Human Histamine H4 Receptor.
ChemMedChem 4 (5), pp. 820-827.
Fulltext not available.
Elbakry, Asmaa,
Zaky, A.,
Liebl, Renate,
Rachel, Reinhard,
Göpferich, Achim 
and
Breunig, Miriam 
(2009)
Layer-by-Layer Assembled Gold Nanoparticles for siRNA Delivery.
Nano Letters 9 (5), pp. 2059-2064.
Fulltext not available.
Elbakry, Asmaa,
Zaky, Alaa,
Liebl, Renate,
Rachel, Reinhard,
Goepferich, Achim 
and
Breunig, Miriam 
(2009)
Layer-by-layer assembled gold nanoparticles for siRNA delivery.
Nano letters 9 (5), pp. 2059-2064.
Fulltext not available.
Taha, H. M.,
Schmidt, J.,
Göttle, M.,
Suryanarayana, S.,
Shen, Y.,
Tang, W.-J. 
,
Gille, A. 
,
Geduhn, Jens,
König, Burkhard 
,
Dove, Stefan and
Seifert, Roland
(2009)
Molecular Analysis of the Interaction of Anthrax Adenylyl Cyclase Toxin, Edema Factor, with 2'(3')-O-(N-(methyl)anthraniloyl)-Substituted Purine and Pyrimidine Nucleotides.
Mol. Pharmacol. 75 (3), pp. 693-703.
Fulltext not available.
Appel, Bernhard,
Baumer, Julia,
Eyrich, Daniela,
Sarhan, Hatem,
Taso, S.,
Englert, Carsten 
,
Göpferich, Achim,
make_name_string expected hash reference,
make_name_string expected hash reference,
make_name_string expected hash reference 
and
make_name_string expected hash reference
(2009)
Synergistic effects of growth and differentiation factor-5 (GDF-5) and insulin on expanded chondrocytes in a 3-D environment.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 17 (11), pp. 1503-1512.
Fulltext not available.
Keller, Max,
Pop, Nathalie,
Hutzler, Christoph 
,
Beck-Sickinger, Annette G.,
Bernhardt, Günther and
Buschauer, Armin
(2008)
Guanidine - acylguanidine bioisosteric approach in the design of radioligands: Synthesis of a tritium-labeled N(G)-propionylargininamide ([3H]UR-MK114) as a highly potent and selective neuropeptide Y Y1 receptor antagonist.
Journal of Medicinal Chemistry 51 (24), pp. 8168-8172.
Fulltext not available.
Ghorai, Prasanta,
Kraus, Anja,
Keller, Max,
Götte, Carsten,
Igel, Patrick,
Schneider, Erich 
,
Schnell, David,
Bernhardt, Günther,
Dove, Stefan,
Zabel, Manfred,
Elz, Sigurd,
Seifert, Roland and
Buschauer, Armin
(2008)
Acylguanidines as bioisosteres of guanidines: N(G)-acylated imidazolylpropylguanidines, a new class of histamine H2 receptor agonists.
Journal of Medicinal Chemistry 51 (22), pp. 7193-7204.
Fulltext not available.
Spangler, Corinna M.,
Spangler, Christian,
Göttle, Martin,
Shen, Yuequan,
Tang, Wei-Jen 
,
Seifert, Roland and
Schäferling, Michael
(2008)
A fluorimetric assay for real-time monitoring of adenylyl cyclase activity based on terbium norfloxacin.
Analytical Biochemistry 381 (1), pp. 86-93.
Fulltext not available.
Pinto, Cibele,
Papa, Dan,
Hübner, Melanie,
Mou, Tung-Chung,
Lushington, Gerald H. and
Seifert, Roland
(2008)
Activation and Inhibition of Adenylyl Cyclase Isoforms by Forskolin Analogs.
Journal of Pharmacology and Experimental Therapeutics 325 (1), pp. 27-36.
Fulltext not available.
Koelwel, C.,
Rothschenk, Stefan,
Fuchs-Koelwel, B.,
Gabler, B.,
Lohmann, C. and
Göpferich, Achim 
(2008)
Alginate inserts loaded with epidermal growth factor for the treatment of keratoconjunctivitis sicca.
Pharmaceutical Development and Technology 13 (3), pp. 221-231.
Fulltext not available.
Vogel, Susanne,
Kaufmann, Doris,
Pojarová, Michaela,
Müller, Christine,
Pfaller, Tobias,
Kühne, Sybille,
Bednarski, Patrick J. and
Angerer, Erwin von
(2008)
Aroyl hydrazones of 2-phenylindole-3-carbaldehydes as novel antimitotic agents.
Bioorganic & Medicinal Chemistry 16 (12), pp. 6436-6447.
Fulltext not available.
Wagenlehner, F.M.E.,
Kees, F.,
Weidner, W.,
Wagenlehner, C. and
Naber, K.G.
(2008)
Concentrations of moxifloxacin in plasma and urine, and penetration into prostatic fluid and ejaculate, following single oral administration of 400mg to healthy volunteers.
International Journal of Antimicrobial Agents 31 (1), pp. 21-26.
Fulltext not available.
Fang, Lei,
Kraus, Birgit,
Lehmann, Jochen,
Heilmann, Joerg,
Zhang, Yihua and
Decker, Michael
(2008)
Design and synthesis of tacrine–ferulic acid hybrids as multi-potent anti-Alzheimer drug candidates.
Bioorganic & Medicinal Chemistry Letters 18 (9), pp. 2905-2909.
Fulltext not available.
Hubensack, Martina,
Müller, Christine,
Höcherl, Höcherl,
Fellner, Stephan,
Spruss, Thilo,
Bernhardt, Günther and
Buschauer, Armin
(2008)
Effect of the ABCB1 modulators elacridar and tariquidar on the distribution of paclitaxel in nude mice.
Journal of Cancer Research and Clinical Oncology 134 (5), pp. 597-607.
Fulltext restricted.
Beule, A. G.,
Scharf, C.,
Biebler, K.-E.,
Göpferich, Achim,
Steinmeier, E.,
Wolf, E.,
Hosemann, W. and
Kaftan, H.
(2008)
Effects of Topically Applied Dexamethasone on Mucosal Wound Healing Using a Drug-Releasing Stent.
The Laryngoscope 118 (11), pp. 2073-2077.
Fulltext not available.
Beule, Achim G. 
,
Scharf, Christian 
,
Biebler, Karl‐Ernst,
Göpferich, Achim 
,
Steinmeier, Elke,
Wolf, Eduard,
Hosemann, Werner and
Kaftan, Holger
(2008)
Effects of Topically Applied Dexamethasone on Mucosal Wound Healing Using a Drug‐Releasing Stent.
The Laryngoscope 118 (11), pp. 2073-2077.
Fulltext not available.
Sommer, Florian,
Pollinger, Klaus,
Brandl, Ferdinand,
Weiser, Barbara,
Teßmar, Jörg 
,
Blunk, Torsten and
Göpferich, Achim 
(2008)
Hyalocyte proliferation and ECM accumulation modulated by bFGF and TGF-β1.
Graefe's Archive for Clinical and Experimental Ophthalmology 246 (9), pp. 1275-1284.
Fulltext not available.
Weiser, Barbara,
Prantl, Lukas,
Schubert, Thomas E. O.,
Zellner, J. 
,
Fischbach-Teschl, Claudia,
Spruss, Thilo,
Seitz, Anna Katharina,
Teßmar, Jörg 
,
Göpferich, Achim 
and
Blunk, Torsten
(2008)
In Vivo Development and Long-Term Survival of Engineered Adipose Tissue Depend on In Vitro Precultivation Strategy.
Tissue Engineering Part A 14 (2), pp. 275-284.
Fulltext not available.
Mahboobi, Siavosh,
Sellmer, Andreas,
Eswayah, Asma,
Elz, Sigurd,
Uecker, Andrea and
Böhmer, Frank-D.
(2008)
Inhibition of PDGFR tyrosine kinase activity by a series of novel N-(3-(4-(pyridin-3-yl)-1H-imidazol-2-ylamino)phenyl)amides: a SAR study on the bioisosterism of pyrimidine and imidazole.
European journal of medicinal chemistry 43 (7), pp. 1444-1453.
Fulltext not available.
Breunig, Miriam 
,
Hosza, C.,
Lungwitz, Uta,
Watanabe, K.,
Umeda, I.,
Kato, H. and
Göpferich, Achim 
(2008)
Mechanistic investigation of poly(ethylene imine)-based siRNA delivery: Disulfide bonds boost intracellular release of the cargo.
Journal of Controlled Release 130 (1), pp. 57-63.
Fulltext not available.
Dai, Jisen,
Jian, Jinlong,
Bosland, Maarten,
Frenkel, Krystyna,
Bernhardt, Günther and
Huang, Xi
(2008)
Roles of hormone replacement therapy and iron in proliferation of breast epithelial cells with different estrogen and progesterone receptor status.
Breast (Edinburgh, Scotland) 17 (2), pp. 172-179.
Fulltext not available.
Vlachy, N.,
Merle, C.,
Touraud, D.,
Schmidt, J.,
Talmon, Y.,
Heilmann, J. and
Kunz, W. 
(2008)
Spontaneous Formation of Bilayers and Vesicles in Mixtures of Single-Chain Alkyl Carboxylates: Effect of pH and Aging and Cytotoxicity Studies.
Langmuir 24 (18), pp. 9983-9988.
Fulltext not available.
Egger, M.,
Pellett, P.,
Nickl, K.,
Geiger, S.,
Graetz, S.,
Seifert, R.,
Heilmann, J. and
König, B. 
(2008)
Synthesis and Cannabinoid Receptor Activity of Ketoalkenes from Echinacea pallida and Non-natural Analogues.
Chem. Eur. J. 14, 10978 - 10984.
Fulltext not available.
Hellerbrand, C,
Amann, T,
Schlegel, J,
Wild, P,
Bataille, F,
Spruss, T,
Hartmann, A and
Bosserhoff, A-K 
(2008)
The novel gene MIA2 acts as a tumour suppressor in hepatocellular carcinoma.
Gut 57 (2), pp. 243-251.
Fulltext not available.
Schmidtko, Achim,
Gao, Wei,
König, Peter,
Heine, Sandra,
Motterlini, Roberto 
,
Ruth, Peter,
Schlossmann, Jens 
,
Koesling, Doris,
Niederberger, Ellen,
Tegeder, Irmgard 
,
Friebe, Andreas and
Geisslinger, Gerd
(2008)
cGMP Produced by NO-Sensitive Guanylyl Cyclase Essentially Contributes to Inflammatory and Neuropathic Pain by Using Targets Different from cGMP-Dependent Protein Kinase I.
The Journal of Neuroscience 28 (34), pp. 8568-8576.
Fulltext not available.
Göttle, Martin,
Dove, Stefan,
Steindel, Phillip,
Shen, Yuequan,
Tang, Wei-Jen 
,
Geduhn, Jens,
König, Burkhard 
and
Seifert, Roland
(2007)
Molecular Analysis of the Interaction of Bordetella pertussis Adenylyl Cyclase with Fluorescent Nucleotides.
Molecular Pharmacology 72 (3), pp. 526-535.
Wang, Jenna L.,
Guo, Jian-Xin,
Zhang, Qi-Yuan,
Wu, Jay J.-Q.,
Seifert, Roland and
Lushington, Gerald H.
(2007)
A conformational transition in the adenylyl cyclase catalytic site yields different binding modes for ribosyl-modified
and unmodified nucleotide inhibitors.
Bioorganic & Medicinal Chemistry 15 (8), pp. 2993-3002.
Preuss, Hendrik,
Ghorai, Prasanta,
Kraus, Anja,
Dove, Stefan,
Buschauer, Armin and
Seifert, Roland
(2007)
Constitutive Activity and Ligand Selectivity of Human,
Guinea Pig, Rat, and Canine Histamine H₂ Receptors.
Journal of Pharmacology and Experimental Therapeutics 321 (3), pp. 983-995.
Preuss, Hendrik,
Ghorai, Prasanta,
Kraus, Anja,
Dove, Stefan,
Buschauer, Armin and
Seifert, Roland
(2007)
Mutations of Cys-17 and Ala-271 in the Human Histamine H₂
Receptor Determine the Species Selectivity of Guanidine-Type Agonists and Increase Constitutive Activity.
Journal of Pharmacology and Experimental Therapeutics 321 (3), pp. 975-982.
Kaufmann, Doris,
Pojarová, Michaela,
Vogel, Susanne,
Liebl, Renate,
Gastpar, Robert,
Gross, Dietmar,
Nishino, Tsuyuki,
Pfaller, Tobias and
Angerer, Erwin von
(2007)
Antimitotic activities of 2-phenylindole-3-carbaldehydes in human breast cancer cells.
Bioorganic & medicinal chemistry 15 (15), pp. 5122-36.
Fulltext not available.
Sommer, Florian,
Kobuch, Karin,
Brandl, Ferdinand,
Wild, Brigitte,
Framme, Carsten,
Weiser, Barbara,
Tessmar, Joerg 
,
Gabel, Veit-Peter,
Blunk, Torsten and
Goepferich, Achim 
(2007)
Ascorbic Acid Modulates Proliferation and Extracellular Matrix Accumulation of Hyalocytes.
Tissue Engineering 13 (6), pp. 1281-1289.
Fulltext not available.
Englert, Carsten 
,
Blunk, Torsten,
Müller, Rainer 
,
Schulze, S.,
Baumer, Julia,
Fierlbeck, J.,
Heid, I.,
Nerlich, Michael and
Hammer, J.
(2007)
Bonding of articular cartilage utilising a combination of biochemical degradation and surface cross-linking.
Arthritis Research & Therapy 9 (3), R47.
Ziemek, Ralf,
Schneider, Erich 
,
Kraus, Anja,
Cabrele, Chiara 
,
Beck-Sickinger, Annette G.,
Bernhardt, Günther and
Buschauer, Armin
(2007)
Determination of affinity and activity of ligands at the human neuropeptide Y Y4 receptor by flow cytometry and aequorin luminescence.
Journal of Receptors and Signal Transduction 27 (4), pp. 217-233.
Fulltext not available.
Maschke, Angelika,
Becker, Christian,
Eyrich, Daniela,
Kiermaier, Josef,
Blunk, Torsten and
Göpferich, Achim 
(2007)
Development of a spray congealing process for the preparation of insulin-loaded lipid microparticles and characterization thereof.
European Journal of Pharmaceutics and Biopharmaceutics 65 (2), pp. 175-187.
Fulltext not available.
Schlegel, Birgit,
Laggner, Christian,
Meier, Rene 
,
Langer, Thierry 
,
Schnell, David,
Seifert, Roland,
Stark, Holger 
,
Höltje, Hans-Dieter and
Sippl, Wolfgang 
(2007)
Generation of a homology model of the human histamine H₃ receptor for ligand docking and pharmacophore-based screening.
Journal of Computer-Aided Molecular Design.
Romagnoli, Romeo,
Baraldi, Pier Giovanni,
Carrion, Maria Dora 
,
Cruz-Lopez, Olga,
Preti, Delia,
Tabrizi, Mojgan Aghazadeh,
Fruttarolo, Francesca,
Heilmann, Jörg,
Bermejo, Jaime and
Estévez, Francisco 
(2007)
Hybrid molecules containing benzo[4,5]imidazo[1,2-d][1,2,4]thiadiazole and α-bromoacryloyl moieties as potent apoptosis inducers on human myeloid leukaemia cells.
Bioorganic & Medicinal Chemistry Letters 17 (10), pp. 2844-2848.
Fulltext not available.
Mahboobi, Siavosh,
Uecker, Andrea,
Cénac, Christophe,
Sellmer, Andreas,
Eichhorn, Emerich,
Elz, Sigurd,
Böhmer, Frank-D. and
Dove, Stefan
(2007)
Inhibition of FLT3 and PDGFR tyrosine kinase activity by bis(benzo[b]furan-2-yl)methanones.
Bioorganic & Medicinal Chemistry 15 (5), pp. 2187-2197.
Fulltext not available.
Müller, Christine,
Gross, Dietmar,
Sarli, Vasiliki,
Gartner, Michael,
Giannis, Athanassios,
Bernhardt, Günther and
Buschauer, Armin
(2007)
Inhibitors of kinesin Eg5: antiproliferative activity of monastrol analogues against human glioblastoma cells.
Cancer Chemotherapy and Pharmacology 59 (2), pp. 157-164.
Fulltext not available.
Eyrich, Daniela,
Brandl, Ferdinand,
Appel, Bernhard,
Wiese, Hinrich 
,
Maier, Gerhard,
Wenzel, Magdalene,
Staudenmaier, Rainer,
Goepferich, Achim 
and
Blunk, Torsten
(2007)
Long-term stable fibrin gels for cartilage engineering.
Biomaterials 28 (1), pp. 55-65.
Fulltext not available.
Math´e, A.A.,
Gruber, S.H.M,
El Khoury, A.,
Beiderbeck, D.,
Neumann, I.D. and
Landgraf, R.
(2007)
P.4.b.002 Brain biochemistry markers differentiate between animal models of anxiety and depression.
European Neuropsychopharmacology 17, S510-S511.
Fulltext not available.
Schertl, Sabine,
Hartmann, Rolf W.,
Batzl-Hartmann, Christine,
Spruss, Thilo,
Maucher, Anton,
Angerer, Erwin von,
Schiller, Claus D.,
Schneider, Martin R.,
Gust, Ronald and
Schönenberger, Helmut
(2007)
Platinum(II) complexes interfering with testicular steroid biosynthesis: drugs for the therapy of advanced or recurrent prostate cancers? Preclinical studies.
Journal of Cancer Research and Clinical Oncology 133 (3), pp. 153-167.
Fulltext not available.
Preuss, Hendrik,
Ghorai, Prasanta,
Kraus, Anja,
Dove, Stefan,
Buschauer, Armin and
Seifert, Roland
(2007)
Point Mutations in the Second Extracellular Loop of the Histamine H2 Receptor do not affect the Species-Selective Activity of Guanidine-Type Agonists.
Naunyn Schmiedebergs Arch. Pharmacol. 376 (4), pp. 253-264.
Fulltext restricted.
Brandl, F.,
Henke, M.,
Rothschenk, S.,
Gschwind, R. M. 
,
Breunig, M. 
,
Tessmar, J.,
Goepferich, Achim 
and
make_name_string expected hash reference 
(2007)
Poly(ethylene glycol) based hydrogels for intraocular applications.
Advanced Engineering Materials 9 (12), pp. 1141-1149.
Fulltext not available.
Hofinger, Edith S. A.,
Spickenreither, Martin,
Oschmann, Jan,
Bernhardt, Günther,
Rudolph, Rainer and
Buschauer, Armin
(2007)
Recombinant human hyaluronidase Hyal-1: insect cells versus E. coli as expression system and identification of low molecular weight inhibitors.
Glycobiology 17 (4), pp. 444-453.
Fulltext not available.
Weber, Silke,
Bernhard, Dominik,
Lukowski, Robert,
Weinmeister, Pascal,
Wörner, René,
Wegener, Jörg W.,
Valtcheva, Nadejda,
Feil, Susanne 
,
Schlossmann, Jens 
,
Hofmann, Franz and
Feil, Robert 
(2007)
Rescue of cGMP Kinase I Knockout Mice by Smooth Muscle–Specific Expression of Either Isozyme.
Circulation Research 101 (11), pp. 1096-1103.
Fulltext not available.
Hacker, Michael 
,
Ringhofer, Michael,
Appel, Bernhard,
Neubauer, Markus,
Vogel, Thomas,
Young, Simon 
,
Mikos, Antonios G.,
Blunk, Torsten,
Göpferich, Achim 
and
Schulz, Michaela B.
(2007)
Solid lipid templating of macroporous tissue engineering scaffolds.
Biomaterials 28 (24), pp. 3497-3507.
Fulltext not available.
Schneider, Erich 
,
Keller, Max,
Brennauer, Albert,
Hoefelschweiger, Bianca K.,
Gross, Dietmar,
Wolfbeis, Otto S. 
,
Bernhardt, Günther and
Buschauer, Armin
(2007)
Synthesis and Characterization of the First Fluorescent Nonpeptide NPY Y1 Receptor Antagonist.
ChemBioChem 8 (16), pp. 1981-1988.
Fulltext restricted.
Egger, Michael,
Li, Xuqin,
Müller, Christine,
Bernhardt, Günther,
Buschauer, Armin and
König, Burkhard 
(2007)
Tariquidar analogues: synthesis by Cu(I)-catalysed N/O–aryl coupling and inhibitory activity against the ABCB1 transporter.
European Journal of Organic Chemistry 2007 (16), pp. 2643-2649.
Fulltext not available.
Hajak, Göran,
Langguth, Berthold,
Landgrebe, M.,
Sand, P. 
and
Eichhammer, Peter
(2007)
Thalamic gating, schizophrenia and antipsychotic treatment – an investigation with TMS.
Pharmacopsychiatry 40 (05), A077.
Fulltext not available.
Pojarová, Michaela,
Kaufmann, Doris,
Gastpar, Robert,
Nishino, Tsuyuki,
Reszka, Przemyslaw,
Bednarski, Patrick J. and
Angerer, Erwin von
(2007)
[(2-Phenylindol-3-yl)methylene]propanedinitriles inhibit the growth of breast cancer cells by cell cycle arrest in G(2)/M phase and apoptosis.
Bioorganic & medicinal chemistry 15 (23), pp. 7368-7379.
Fulltext not available.
Amann, T.,
Spruss, T.,
Bataille, F.,
Liedtke, C.,
Muhlbauer, M.,
Trautwein, C.,
Bosserhoff, A.K. and
Hellerbrand, C.
(2007)
[69] IDENTIFICATION OF FIBROBLAST GROWTH FACTOR RECEPTOR 2IIIB (FGFR2IIIB) AS TUMOR SUPPRESSOR IN HEPATOCANCEROGENESIS.
Journal of Hepatology 46, S31.
Fulltext not available.
Kees, Frieder,
Bucher, Michael,
Schweda, Frank,
Gschaidmeier, Harald,
Burhenne, Juergen 
,
Mikus, Gerd 
and
Faerber, Lothar
(2006)
Comparative bioavailability of the microemulsion formulation of cyclosporine (Neoral) with a generic dispersion formulation (Cicloral) in young healthy male volunteers.
Therapeutic drug monitoring 28 (3), pp. 312-320.
Fulltext restricted.
Xie, Sheng-Xue,
Kraus, Anja,
Ghorai, Prasanta,
Ye, Qi-Zhuang,
Elz, Sigurd,
Buschauer, Armin and
Seifert, Roland
(2006)
N1-(3-Cyclohexylbutanoyl)-N2-[3-(1H-imidazol-4-
yl)propyl]guanidine (UR-AK57), a Potent Partial Agonist for the Human Histamine H1- and H2- Receptors.
Journal of Pharmacology and Experimental Therapeutics 317 (3), pp. 1262-1268.
Fulltext restricted.
Wabnitz, Tobias C.,
Rizzo, Simona 
,
Götte, Carsten,
Buschauer, Armin,
Benincori, Tiziana 
and
Reiser, Oliver 
(2006)
Enantioselective hydrogenation of diaryl-substituted a,b-unsaturated nitriles.
Tetrahedron Letters 47 (22), pp. 3733-3736.
Fulltext not available.
Bucher, Michael,
Kees, Frieder K.,
Messmann, Barbara,
Lunz, Dirk,
Rath, Stephan,
Zelenka, Marek,
Schlitt, Hans J. and
Hobbhahn, Jonny
(2006)
Prostaglandin I2 release following mesenteric traction during abdominal surgery is mediated by cyclooxygenase-1.
European journal of pharmacology 536 (3), pp. 296-300.
Fulltext restricted.
Mahboobi, Siavosh,
Eichhorn, Emerich,
Popp, Alfred,
Sellmer, Andreas,
Elz, Sigurd and
Möllmann, Ute
(2006)
3-Bromo-4-(1H-3-indolyl)-2,5-dihydro-1H-2,5-pyrroledione derivatives as new lead compounds for antibacterially active substances.
European Journal of Medicinal Chemistry 41 (2), pp. 176-191.
Fulltext not available.
Hellerbrand, C.,
Amann, T.,
Schlegel, J.,
Spruss, T.,
Bataille, F.,
Hartmann, A.,
Mühlbauer, M.,
Schölmerich, J. and
Bosserhoff, A.K.
(2006)
98 The novel gene MIA2 promotes progression of hepatocellular carcinoma.
Journal of Hepatology 44, S43.
Fulltext not available.
Schneider, Erich 
,
Mayer, Matthias,
Ziemek, Ralf,
Li, Liantao,
Hutzler, Christoph 
,
Bernhardt, Günther and
Buschauer, Armin
(2006)
A Simple and Powerful Flow Cytometric Method for the Simultaneous Determination of Multiple Parameters at G-Protein-coupled Receptor Subtypes.
ChemBioChem 7 (9), pp. 1400-1409.
Fulltext not available.
Guse, C.,
Koennings, S.,
Maschke, A.,
Hacker, M. 
,
Becker, C.,
Schreiner, S.,
Blunk, T.,
Spruss, T. and
Goepferich, A. 
(2006)
Biocompatibility and erosion behavior of implants made of triglycerides and blends with cholesterol and phospholipids.
International Journal of Pharmaceutics 314 (2), pp. 153-160.
Fulltext not available.
Fischer, Thomas,
Bohmer, Frank D.,
Huber, Christoph,
Dove, Stefan,
Breitenbucher, Frank,
Mirea, Fian K. and
Heidel, Florian
(2006)
Bis(1H-indol-2yl)methanones Are Effective Inhibitors of Mutated FLT3 Tyrosine Kinase, Overcome Resistance to PKC412A In Vitro and Show Synergy with Chemotherapy.
Blood 108 (11), p. 1369.
Fulltext not available.
Mou, Tung-Chung,
Gille, Andreas 
,
Suryanarayana, Srividya,
Richter, Mark,
Seifert, Roland and
Sprang, Stephen R.
(2006)
Broad Specificity of Mammalian Adenylyl Cyclase for Interaction with 2′,3′-Substituted Purine- and Pyrimidine Nucleotide Inhibitors.
Molecular Pharmacology 70 (3), pp. 878-886.
Fulltext not available.
Rigden, Daniel J. 
,
Botzki, Alexander 
,
Nukui, Masatoshi,
Mewbourne, R. Brandon,
Lamani, Ejvis,
Braun, Stephan,
von Angerer, Erwin,
Bernhardt, Günther,
Dove, Stefan,
Buschauer, Armin and
Jedrzejas, Mark J.
(2006)
Design of new benzoxazole-2-thione derived inhibitors of Streptococcus pneumoniae hyaluronan lyase: structure of a complex with a 2-phenylindole.
Glycobiology 16 (8), pp. 757-765.
Fulltext not available.
Guse, C.,
Koennings, S.,
Kreye, F.,
Siepmann, F. 
,
Goepferich, A. 
and
Siepmann, J. 
(2006)
Drug release from lipid-based implants: Elucidation of the underlying mass transport mechanisms.
International Journal of Pharmaceutics 314 (2), pp. 137-144.
Fulltext not available.
Kelber, O. 
,
Wittwer, A.,
Lapke, C.,
Kroll, U.,
Weiser, D.,
Okpanyi, S.N. and
Heilmann, J.
(2006)
Ex vivo/in vitro absorption of STW 5 (Iberogast®) and its extract components.
Phytomedicine 13, pp. 107-113.
Fulltext not available.
Koennings, S.,
Garcion, E.,
Faisant, N.,
Menei, P.,
Benoit, J.P. and
Goepferich, A. 
(2006)
In vitro investigation of lipid implants as a controlled release system for interleukin-18.
International Journal of Pharmaceutics 314 (2), pp. 145-152.
Fulltext not available.
Appel, B.,
Maschke, A.,
Weiser, B.,
Sarhan, H.,
Englert, C. 
,
Angele, P.,
Blunk, T. and
Göpferich, A. 
(2006)
Lipidic implants for controlled release of bioactive insulin: Effects on cartilage engineered in vitro.
International Journal of Pharmaceutics 314 (2), pp. 170-178.
Fulltext not available.
Weinrich, Malte,
Scheingraber, Stefan,
Stremovskaia, Tatiana,
Schilling, Martin K.,
Kees, Frieder and
Pistorius, Georg A.
(2006)
Liver tissue concentrations of levofloxacin after single intravenous administration of 500mg for antibiotic prophylaxis in liver surgery.
International Journal of Antimicrobial Agents 28 (3), pp. 221-225.
Fulltext not available.
Knerr, Robert,
Weiser, Barbara,
Drotleff, Sigrid,
Steinem, Claudia and
Göpferich, Achim 
(2006)
Measuring Cell Adhesion on RGD‐Modified, Self‐Assembled PEG Monolayers Using the Quartz Crystal Microbalance Technique.
Macromolecular Bioscience 6 (10), pp. 827-838.
Fulltext not available.
Maschke, Angelika,
Calí, Nadia,
Appel, Bernhard,
Kiermaier, Josef,
Blunk, Torsten and
Göpferich, Achim 
(2006)
Micronization of Insulin by High Pressure Homogenization.
Pharmaceutical Research 23 (9), pp. 2220-2229.
Fulltext not available.
Heilmann, J,
Htay Shwe, H,
Aye, M,
Sein, MM,
Kreitmeier, P and
Reiser, O
(2006)
New Furostanol Glycosides from the Rhizomes of Tacca integrifolia.
Planta Medica 72 (11).
Fulltext not available.
Mahboobi, Siavosh,
Uecker, Andrea,
Sellmer, Andreas,
Cénac, Christophe,
Höcher, Heymo,
Pongratz, Herwig,
Eichhorn, Emerich,
Hufsky, Harald,
Trümpler, Antje,
Sicker, Marit,
Heidel, Florian,
Fischer, Thomas,
Stocking, Carol,
Elz, Sigurd,
Böhmer, Frank-D. and
Dove, Stefan
(2006)
Novel Bis(1H-indol-2-yl)methanones as Potent Inhibitors of FLT3 and Platelet-Derived Growth Factor Receptor Tyrosine Kinase.
Journal of Medicinal Chemistry 49 (11), pp. 3101-3115.
Fulltext not available.
Elkharraz, K.,
Faisant, N.,
Guse, C.,
Siepmann, F. 
,
Arica-Yegin, B.,
Oger, J.M.,
Gust, R.,
Goepferich, A. 
,
Benoit, J.P. and
Siepmann, J. 
(2006)
Paclitaxel-loaded microparticles and implants for the treatment of brain cancer: Preparation and physicochemical characterization.
International Journal of Pharmaceutics 314 (2), pp. 127-136.
Fulltext not available.
Xie, Sheng-Xue,
Petrache, Georgiana,
Schneider, Erich 
,
Ye, Qi-Zhuang,
Bernhardt, Günther,
Seifert, Roland and
Buschauer, Armin
(2006)
Synthesis and pharmacological characterization of novel fluorescent histamine H2-receptor ligands derived from aminopotentidine.
Bioorganic & Medicinal Chemistry Letters 16 (15), pp. 3886-3890.
Fulltext not available.
Neubauer, Markus,
Hacker, Michael 
,
Bauer-Kreisel, Petra,
Weiser, Barbara,
Fischbach, Claudia 
,
Schulz, Michaela B,
Goepferich, Achim 
and
Blunk, Torsten
(2005)
Adipose Tissue Engineering Based on Mesenchymal Stem Cells and Basic Fibroblast Growth Factorin Vitro.
Tissue Engineering 11 (11-12), pp. 1840-1851.
Fulltext not available.
Gille, Andreas 
,
Guo, Jianxin,
Mou, Tung-Chung,
Doughty, Michael B.,
Lushington, Gerald H. and
Seifert, Roland
(2005)
Differential interactions of G-proteins and adenylyl cyclase with nucleoside 5′-triphosphates, nucleoside 5′-[γ-thio]triphosphates and nucleoside 5′-[β,γ-imido]triphosphates.
Biochemical Pharmacology 71 (1-2), pp. 89-97.
Fulltext not available.
Breunig, Miriam 
,
Lungwitz, Uta,
Liebl, Renate,
Fontanari, Claudia,
Klar, Juergen,
Kurtz, Armin,
Blunk, Torsten and
Goepferich, Achim 
(2005)
Gene delivery with low molecular weight linear polyethylenimines.
The Journal of Gene Medicine 7 (10), pp. 1287-1298.
Fulltext not available.
Ito, Natsuho,
Ito, Taisuke,
Kromminga, Arno,
Bettermann, Albrecht,
Takigawa, Masahiro,
Kees, Frieder,
Straub, Rainer H. and
Paus, Ralf
(2005)
Human hair follicles display a functional equivalent of the hypothalamic‐pituitary‐adrenal (HPA) axis and synthesize cortisol.
The FASEB Journal 19 (10), pp. 1332-1334.
Fulltext not available.
Lieb, E.,
Hacker, M. 
,
Tessmar, J. 
,
Kunz-Schughart, L.A.,
Fiedler, J.,
Dahmen, C.,
Hersel, U.,
Kessler, H.,
Schulz, M.B. and
Göpferich, A.
(2005)
Mediating specific cell adhesion to low-adhesive diblock copolymers by instant modification with cyclic RGD peptides.
Biomaterials 26 (15), pp. 2333-2341.
Fulltext not available.
Salmen, Sunnhild,
Hoechstetter, Julia,
Käsbauer, Christian,
Paper, Dieter H.,
Bernhardt, Günther and
Buschauer, Armin
(2005)
Sulphated Oligosaccharides as Inhibitors of Hyaluronidases from Bovine Testis, Bee Venom and Streptococcus agalactiae.
Planta Med. 71, pp. 727-732.
Fulltext not available.
Romagnoli, Romeo,
Baraldi, Pier Giovanni,
Iaconinoto, Maria Antonietta,
Carrion, Maria Dora 
,
Tabrizi, Mojgan Aghazadeh,
Gambari, Roberto 
,
Borgatti, Monica 
and
Heilmann, Jörg
(2005)
Synthesis and biological activity of alpha-bromoacryloyl lexitropsin conjugates.
European Journal of Medicinal Chemistry 40 (11), pp. 1123-1128.
Fulltext not available.
Mahboobi, Siavosh,
Sellmer, Andreas,
Eichhorn, Emerich,
Beckers, Thomas,
Fiebig, Heinz-Herbert and
Kelter, Gerhard
(2005)
Synthesis and cytotoxic activity of 2-acyl-1H-indole-4,7-diones on human cancer cell lines.
European Journal of Medicinal Chemistry 40 (1), pp. 85-92.
Fulltext not available.
Kaftan, H.,
Hosemann, W.,
Junghans, D.,
Göpferich, A.,
Schindler, E. and
Beule, A.
(2005)
Traumatische Trommelfellperforationen.
HNO 53 (6), pp. 539-544.
Fulltext not available.
Kießling, Stephan,
Müller-Newen, Gerhard,
Leeb, Sandra N.,
Hausmann, Martin,
Rath, Heiko C.,
Strater, Jörn,
Spottl, Tanja,
Schlottmann, Klaus,
Grossmann, Johannes,
Montero-Julian, F. A.,
Schölmerich, Jürgen,
Andus, Tilo,
Buschauer, Armin,
Heinrich, Peter C. and
Rogler, Gerhard 
(2004)
Functional Expression of the Interleukin-11 Receptor α-Chain and Evidence of Antiapoptotic Effects in Human Colonic Epithelial Cells.
The Journal of Biological Chemistry 279 (11), pp. 10304-10315.
Fulltext not available.
Neubauer, Markus,
Fischbach, Claudia 
,
Bauer-Kreisel, Petra,
Lieb, Esther,
Hacker, Michael 
,
Tessmar, Joerg 
,
Schulz, Michaela B.,
Goepferich, Achim 
and
Blunk, Torsten
(2004)
Basic fibroblast growth factor enhances PPARγ ligand‐induced adipogenesis of mesenchymal stem cells.
FEBS Letters 577 (1-2), pp. 277-283.
Fulltext not available.
Ménard, Rozenn,
Alban, Susanne,
de Ruffray, Patrice,
Jamois, Frank,
Franz, Gerhard,
Fritig, Bernard,
Yvin, Jean-Claude and
Kauffmann, Serge
(2004)
Beta-1,3 glucan sulfate, but not beta-1,3 glucan, induces the salicylic acid signaling pathway in tobacco and Arabidopsis.
The Plant Cell 16 (11), pp. 3020-3032.
Fulltext not available.
Drotleff, S,
Lungwitz, U,
Breunig, M 
,
Dennis, A,
Blunk, T,
Tessmar, J 
and
Göpferich, A
(2004)
Biomimetic polymers in pharmaceutical and biomedical sciences.
European Journal of Pharmaceutics and Biopharmaceutics 58 (2), pp. 385-407.
Fulltext not available.
Bernhardt, Günther,
Brunner, Henri,
Gruber, Nick,
Lottner, Christian,
Pushpan, Simi K.,
Tsuno, Takashi 
and
Zabel, Manfred
(2004)
Carboplatin derivatives with superior antitumor activity compared to the parent compound.
Inorganica Chimica Acta 357 (15), pp. 4452-4466.
Fulltext not available.
Dittmar, Michael,
Kiourkenidis, Georgios,
Horn, Markus,
Bollwein, Susanne and
Bernhardt, Günther
(2004)
Cerebral Ischemia, Matrix Metalloproteinases, and TNF-α: MMP Inhibitors May Act Not Exclusively by Reducing MMP Activity.
Stroke 35 (7).
Fulltext not available.
Gürtler, Ulrich,
Fuchs, Peter,
Stangelmayer, Achim,
Bernhardt, Günther,
Buschauer, Armin and
Spruss, Thilo
(2004)
Construction and validation of a microprocessor controlled extracorporal circuit in rats for the optimization of isolated limb perfusion.
Archiv der Pharmazie 33 (12), pp. 672-681.
Fulltext not available.
Lieb, E.,
Milz, S. 
,
Vogel, T.,
Hacker, M. 
,
Dauner, M. and
Schulz, M.B.
(2004)
Effects of Transforming Growth Factor β1 on Bonelike Tissue Formation in Three-Dimensional Cell Culture. I. Culture Conditions and Tissue Formation.
Tissue Engineering 10 (9-10), pp. 1399-1413.
Fulltext not available.
Demirci, Betül 
,
Paper, Dietrich H.,
Demirci, Fatih 
,
Başer, K. Hüsnü Can and
Franz, Gerhard
(2004)
Essential Oil of Betula pendula Roth. Buds.
Evidence-based complementary and alternative medicine : eCAM 1 (3), pp. 301-303.
Fulltext not available.
Fischbach, Claudia 
,
Spruß, Thilo,
Weiser, Barbara,
Neubauer, Markus,
Becker, Christian,
Hacker, Michael 
,
Göpferich, Achim and
Blunk, Torsten
(2004)
Generation of mature fat pads in vitro and in vivo utilizing 3-D long-term culture of 3T3-L1 preadipocytes.
Experimental Cell Research 300 (1), pp. 54-64.
Fulltext not available.
Breunig, Miriam 
,
Lungwitz, Uta,
Klar, Juergen,
Kurtz, Armin,
Blunk, Torsten and
Goepferich, Achim 
(2004)
Polyplexes of Polyethylenimine and per-N-methylated Polyethylenimine-Cytotoxicity and Transfection Efficiency.
Journal of Nanoscience and Nanotechnology 4 (5), pp. 512-520.
Fulltext not available.
Welsh, Michael,
Welsh, Charlotte,
Ekman, Maria,
Dixelius, Johan,
Hägerkvist, Robert,
Anneren, Cecilia,
Åkerblom, Björn,
Mahboobi, Siavosh,
Chandrasekharan, Subhashini and
Liu, Edison T.
(2004)
The tyrosine kinase FRK/RAK participates in cytokine-induced islet cell cytotoxicity.
Biochemical Journal 382 (1), pp. 261-268.
Fulltext not available.
Fuchs-Koelwel, B.,
Koelwel, C.,
G�pferich, A.,
Gabler, B.,
Wiegrebe, E. and
Lohmann, C. P.
(2004)
Vertr�glichkeit eines neuen Kalzium-Alginat-Insertes zur kontrollierten medikament�sen Therapie am Auge.
Der Ophthalmologe 101 (5), pp. 496-499.
Fulltext not available.
Schertl, Sabine,
Hartmann, Rolf W.,
Batzl-Hartmann, Christine,
Bernhardt, Günther,
Spruß, Thilo,
Beckenlehner, Karin,
Koch, Marion,
Krauser, Rudolf,
Schlemmer, Richard,
Gust, Ronald and
Schönenberger, Helmut
(2004)
[1, 2-Bis(2, 6-difluoro-3-hydroxyphenyl)ethylene-diamine]platinum(II) complexes, compounds for the endocrine therapy of breast cancer - mode of action I: antitumor activity due to the reduction of the endogenous estrogen level.
Archiv der Pharmazie 337 (6), pp. 335-348.
Fulltext not available.
Schertl, Sabine,
Hartmann, Rolf W.,
Batzl-Hartmann, Christine,
Bernhardt, Günther,
Spruss, Thilo,
Beckenlehner, Karin,
Koch, Marion,
Krauser, Rudolf,
Schlemmer, Richard,
Gust, Ronald and
Schönenberger, Helmut
(2004)
[1, 2-Bis(2, 6-difluoro-3-hydroxyphenyl)ethylene-diamine]platinum(II) complexes, compounds for the endocrine therapy of breast cancer - mode of action II: contribution of drug inactivation, cellular drug uptake and sterical factors in the drug-target interaction to the antitumor activity.
Archiv der Pharmazie 337 (6), pp. 349-359.
Fulltext not available.
Botzki, Alexander 
,
Rigden, Daniel J. 
,
Braun, Stephan,
Nukui, Masatoshi,
Salmen, Sunnhild,
Hoechstetter, Julia,
Bernhardt, Günther,
Dove, Stefan,
Jedrzejas, Mark J. and
Buschauer, Armin
(2004)
l-Ascorbic Acid 6-Hexadecanoate, a Potent Hyaluronidase Inhibitor.
Journal of Biological Chemistry 279 (44), pp. 45990-45997.
Fulltext not available.
Li, Liantao,
Mayer, Matthias,
Schneider, Erich 
,
Schreiber, Elvira,
Bernhardt, Günther,
Peng, Shiqi and
Buschauer, Armin
(2003)
Preparation of fluorescent nonpeptidic neuropeptide Y receptor ligands: analogues of the quinazoline-type anti-obesity Y5 antagonist CGP 71683A.
Arch Pharm (Weinheim) 336 (12), pp. 585-590.
Fulltext not available.
Böhmer, Frank D.,
Karagyozov, Luchezar,
Uecker, Andrea,
Serve, Hubert,
Botzki, Alexander 
,
Mahboobi, Siavosh and
Dove, Stefan
(2003)
A Single Amino Acid Exchange Inverts Susceptibility of Related Receptor Tyrosine Kinases for the ATP Site Inhibitor STI-571.
Journal of Biological Chemistry 278 (7), pp. 5148-5155.
Fulltext not available.
Iwasa, Kinuko,
Kuribayashi, Ayako,
Sugiura, Makiko,
Moriyasu, Masataka,
Lee, Dong-Ung and
Wiegrebe, Wolfgang
(2003)
LC–NMR and LC–MS analysis of 2,3,10,11-oxygenated protoberberine metabolites in Corydalis cell cultures.
Phytochemistry 64 (7), pp. 1229-1238.
Fulltext not available.
Vogelhuber, W.,
Magni, E.,
Mouro, M.,
Spruß, T.,
Guse, C.,
Gazzaniga, A. 
and
Göpferich, A.
(2003)
Monolithic Triglyceride Matrices: A Controlled-Release System for Proteins.
Pharmaceutical Development and Technology 8 (1), pp. 71-79.
Fulltext not available.
Menghin, Sonja,
Pertz, Heinz H.,
Kramer, Kai,
Seifert, Roland,
Schunack, Walter and
Elz, Sigurd
(2003)
Nα-Imidazolylalkyl and Pyridylalkyl Derivatives of Histaprodifen: Synthesis and in Vitro Evaluation of Highly Potent Histamine H1-Receptor Agonists.
Journal of Medicinal Chemistry 46 (25), pp. 5458-5470.
Fulltext not available.
Lieb, E.,
Tessmar, J. 
,
Hacker, M. 
,
Fischbach, C. 
,
Rose, D.,
Blunk, T.,
Mikos, A.G.,
Göpferich, A. and
Schulz, M.B.
(2003)
Poly(D,L-lactic acid)-Poly(ethylene glycol)-Monomethyl Ether Diblock Copolymers Control Adhesion and Osteoblastic Differentiation of Marrow Stromal Cells.
Tissue Engineering 9 (1), pp. 71-84.
Fulltext not available.
Krenn, Liselotte 
,
Presser, Armin,
Pradhan, Riddhi,
Bahr, Beate,
Paper, Dietrich H.,
Mayer, Klaus K. and
Kopp, Brigitte
(2003)
Sulfemodin 8-O-β-d-Glucoside, a New Sulfated Anthraquinone Glycoside, and Antioxidant Phenolic Compounds from Rheum emodi.
Journal of Natural Products 66 (8), pp. 1107-1109.
Fulltext not available.
Govoni, Marinella,
Bakker, Remko A.,
van de Wetering, Ineke,
Smit, Martine J.,
Menge, Wiro M. B. P.,
Timmerman, Henk,
Elz, Sigurd,
Schunack, Walter and
Leurs, Rob
(2003)
Synthesis and Pharmacological Identification of Neutral Histamine H1-Receptor Antagonists.
Journal of Medicinal Chemistry 46 (26), pp. 5812-5824.
Fulltext not available.
Li, Liantao,
Kracht, Julia,
Peng, Shiqi,
Bernhardt, Günther and
Buschauer, Armin
(2003)
Synthesis and pharmacological activity of fluorescent histamine H1 receptor antagonists related to mepyramine,.
Bioorganic & Medicinal Chemistry Letters 13 (7), pp. 1245-1248.
Fulltext not available.
Radons, Jürgen,
Dove, Stefan,
Neumann, Detlef 
,
Altmann, Reinhold,
Botzki, Alexander 
,
Martin, Michael U. and
Falk, Werner
(2003)
The Interleukin 1 (IL-1) Receptor Accessory Protein Toll/IL-1 Receptor Domain.
Journal of Biological Chemistry 278 (49), pp. 49145-49153.
Fulltext not available.
Hacker, Michael 
,
Tessmar, Jörg 
,
Neubauer, Markus,
Blaimer, Andrea,
Blunk, Torsten,
Göpferich, Achim and
Schulz, Michaela B
(2003)
Towards biomimetic scaffolds: Anhydrous scaffold fabrication from biodegradable amine-reactive diblock copolymers.
Biomaterials 24 (24), pp. 4459-4473.
Fulltext not available.
Kees, Martin G.,
Pongratz, Georg 
,
Kees, Frieder,
Schölmerich, Jürgen and
Straub, Rainer H. 
(2003)
Via β-adrenoceptors, stimulation of extrasplenic sympathetic nerve fibers inhibits lipopolysaccharide-induced TNF secretion in perfused rat spleen.
Journal of Neuroimmunology 145 (1-2), pp. 77-85.
Fulltext not available.
Lucke, Andrea,
Kiermaier, Josef and
Göpferich, Achim
(2002)
UNSPECIFIED
Pharmaceutical Research 19 (2), pp. 175-181.
Fulltext not available.
Parker, S. L.,
Parker, M. S.,
Lundell, I.,
Balasubramaniam, A.,
Buschauer, Armin,
Kane, J. K.,
Yalcin, A. and
Berglund, M. M.
(2002)
Agonist internalization by cloned Y1 neuropeptide Y (NPY) receptor in Chinese hamster ovary cells shows strong preference for NPY, endosome-linked entry and fast receptor recycling.
Regulatory Peptides 107 (1-3), pp. 49-62.
Fulltext not available.
Apers, Sandra,
Paper, Dietrich,
Bürgermeister, Jutta,
Baronikova, Slavka,
Van Dyck, Stefaan,
Lemière, Guy,
Vlietinck, Arnold and
Pieters, Luc 
(2002)
Antiangiogenic Activity of Synthetic Dihydrobenzofuran Lignans.
Journal of Natural Products 65 (5), pp. 718-720.
Fulltext not available.
Teller, S,
Krämer, D,
Böhmer, S-A,
Tse, KF,
Small, D,
Mahboobi, S,
Wallrapp, C,
Beckers, T,
Kratz-Albers, K,
Schwäble, J,
Serve, H and
Böhmer, F-D
(2002)
Bis(1H-2-indolyl)-1-methanones as inhibitors of the hematopoietic tyrosine kinase Flt3.
Leukemia 16 (8), pp. 1528-1534.
Fulltext not available.
Mahboobi, Siavosh,
Teller, Steffen,
Pongratz, Herwig,
Hufsky, Harald,
Sellmer, Andreas,
Botzki, Alexander 
,
Uecker, Andrea,
Beckers, Thomas,
Baasner, Silke,
Schächtele, Christoph,
Überall, Florian,
Kassack, Matthias U.,
Dove, Stefan and
Böhmer, Frank-D.
(2002)
Bis(1H-2-indolyl)methanones as a Novel Class of Inhibitors of the Platelet-Derived Growth Factor Receptor Kinase.
Journal of Medicinal Chemistry 45 (5), pp. 1002-1018.
Fulltext not available.
Gooch, K.J.,
Blunk, T.,
Courter, D.L.,
Sieminski, A.L.,
Vunjak-Novakovic, G. 
and
Freed, L.E. 
(2002)
Bone Morphogenetic Proteins-2, -12, and -13 Modulatein VitroDevelopment of Engineered Cartilage.
Tissue Engineering 8 (4), pp. 591-601.
Fulltext not available.
Kellner, Karin,
Liebsch, Gregor,
Klimant, Ingo,
Wolfbeis, Otto S. 
,
Blunk, Torsten,
Schulz, Michaela B. and
Göpferich, Achim
(2002)
Determination of oxygen gradients in engineered tissue using a fluorescent sensor.
Biotechnology and Bioengineering 80 (1), pp. 73-83.
Fulltext restricted.
Blunk, Torsten,
Sieminski, Alisha L.,
Gooch, Keith J.,
Courter, Donald L.,
Hollander, Anthony P.,
Nahir, A. Menahem,
Langer, Robert,
Vunjak-Novakovic, Gordana 
and
Freed, Lisa E. 
(2002)
Differential Effects of Growth Factors on Tissue-Engineered Cartilage.
Tissue Engineering 8 (1), pp. 73-84.
Fulltext not available.
El-Subbagh, Hussein,
Wittig, Thomas,
Decker, Michael,
Elz, Sigurd,
Nieger, Martin 
and
Lehmann, Jochen
(2002)
Dopamine/Serotonin Receptor Ligands. Part IV [1]: Synthesis and Pharmacology of Novel 3-Benzazecines and 3-Benzazonines as Potential 5-HT2A and Dopamine Receptor Ligands.
Archiv der Pharmazie 335 (9), pp. 443-448.
Fulltext not available.
Machein, U.,
Buss, B.,
Spiller, I.,
Braun, J.,
Rudwaleit, M.,
Faerber, L. and
Sieper, J.
(2002)
Effective treatment of early rheumatoid arthritis with a combination of methotrexate, prednisolone and cyclosporin.
Rheumatology 41 (1), pp. 110-111.
Fulltext not available.
Kellner, Karin,
Lang, Kurt,
Papadimitriou, Apollon,
Leser, Ulrike,
Milz, Stefan 
,
Schulz, Michaela B.,
Blunk, Torsten and
Göpferich, Achim
(2002)
Effects of Hedgehog Proteins on Tissue Engineering of Cartilagein Vitro.
Tissue Engineering 8 (4), pp. 561-572.
Fulltext not available.
Vogelhuber, Werner,
Spruß, Thilo,
Bernhardt, Günther,
Buschauer, Armin and
Göpferich, Achim
(2002)
Efficacy of BCNU and paclitaxel loaded subcutaneous implants in the interstitial chemotherapy of U-87 MG human glioblastoma xenografts,.
International Journal of Pharmaceutics 238 (1-2), pp. 111-121.
Fulltext not available.
Bernhardt, Günther,
Beckenlehner, Karin,
Spruß, Thilo,
Schlemmer, Richard,
Reile, Herta and
Schönenberger, Helmut
(2002)
Establishment and Characterization of New Murine Breast Cancer Cell Lines.
Archiv der Pharmazie 335 (2-3), pp. 55-68.
Fulltext not available.
Sasse, Astrid 
,
Ligneau, Xavier,
Rouleau, Agnès,
Elz, Sigurd,
Ganellin, C. Robin,
Arrang, Jean-Michel,
Schwartz, Jean-Charles,
Schunack, Walter and
Stark, Holger 
(2002)
Influence of Bulky Substituents on Histamine H3Receptor Agonist/Antagonist Properties.
Journal of Medicinal Chemistry 45 (18), pp. 4000-4010.
Fulltext not available.
Bürgermeister, Jutta,
Paper, Dietrich H,
Vogl, Horst,
Linhardt, Robert J and
Franz, Gerhard
(2002)
LaPSvS1, a (1→3)-β-galactan sulfate and its effect on angiogenesis in vivo and in vitro.
Carbohydrate Research 337 (16), pp. 1459-1466.
Fulltext not available.
Weiss, Thomas S. 
,
Bernhardt, Günther,
Buschauer, Armin,
Thasler, Wolfgang E.,
Dolgner, Doris,
Zirngibl, Hubert and
Jauch, Karl-Walter
(2002)
Polyamine levels of human colorectal adenocarcinomas are correlate with tumor stage and grade,.
International Journal of Colorectal Disease 17 (6), pp. 381-387.
Fulltext not available.
Graßmann, Sven,
Sadek, Bassem,
Ligneau, Xavier,
Elz, Sigurd,
Ganellin, C.Robin,
Arrang, Jean-Michel,
Schwartz, Jean-Charles,
Stark, Holger 
and
Schunack, Walter
(2002)
Progress in the proxifan class: heterocyclic congeners as novel potent and selective histamine H3-receptor antagonists.
European Journal of Pharmaceutical Sciences 15 (4), pp. 367-378.
Fulltext not available.
Höcherl, K.,
Kammerl, M.,
Kees, F.,
Krämer, B. K.,
Grobecker, H. F. and
Kurtz, A.
(2002)
Role of renal nerves in stimulation of renin, COX-2, and nNOS in rat renal cortex during salt deficiency.
American Journal of Physiology-Renal Physiology 282 (3), F478-F484.
Fulltext not available.
Lucke, Andrea,
Fustella, Elisabetta,
Teßmar, Jörg 
,
Gazzaniga, Andrea 
and
Göpferich, Achim
(2002)
The effect of poly(ethylene glycol)–poly(d,l-lactic acid) diblock copolymers on peptide acylation.
Journal of Controlled Release 80 (1-3), pp. 157-168.
Fulltext not available.
Fellner, Stephan,
Bauer, Björn,
Miller, David S.,
Schaffrik, Martina,
Fankhänel, Martina,
Spruß, Thilo,
Bernhardt, Günther,
Graeff, Claudia,
Färber, Lothar,
Gschaidmeier, Harald,
Buschauer, Armin and
Fricker, Gert 
(2002)
Transport of paclitaxel (Taxol) across the blood-brain barrier in vitro and in vivo.
Journal of Clinical Investigation 110 (9), pp. 1309-1318.
Fulltext not available.
Schertl, Sabine,
Hartmann, Rolf W.,
Batzl-Hartmann, Christine,
Schlemmer, Richard,
Spruß, Thilo,
Bernhardt, Günther,
Gust, Ronald and
Schönenberger, Helmut
(2001)
1-(2,6-Dichloro-4-hydroxyphenyl)-2-phenylethanes — New Biological Response Modifiers for the Therapy of Breast Cancer. Synthesis and Evaluation of Estrogenic/Antiestrogenic Properties.
Archiv der Pharmazie 334 (4), pp. 125-137.
Fulltext not available.
Mann, Bianca,
Hartner, Andrea,
Jensen, Boye L.,
Hilgers, Karl F.,
Höcherl, Klaus,
Krämer, Bernhard K. and
Kurtz, Armin
(2001)
Acute upregulation of COX-2 by renal artery stenosis.
American Journal of Physiology-Renal Physiology 280 (1), F119-F125.
Fulltext not available.
Wolf, Konrad,
Kurtz, Armin,
Pfeifer, Michael,
Höcherl, Klaus,
Riegger, Günter and
Krämer, Bernhard
(2001)
Different regulation of left ventricular ANP, BNP and adrenomedullin mRNA in the two-kidney, one-clip model of renovascular hypertension.
Pfl�gers Archiv European Journal of Physiology 442 (2), pp. 212-217.
Fulltext not available.
de Martin, Rainer,
Mrowietz, Ulrich,
Wiegrebe, Wolfgang,
Jirovsky, David,
Loewe, Robert,
Pillinger, Manuela 
,
Gröger, Marion,
Holnthoner, Wolfgang,
Wolff, Klaus and
Petzelbauer, Peter
(2001)
Dimethylfumarate Inhibits Tumor-Necrosis-Factor-Induced CD62E Expression in an NF-κB-Dependent Manner.
Journal of Investigative Dermatology 117 (6), pp. 1363-1368.
Fulltext not available.
Schlemmer, Richard,
Spruß, Thilo,
Bernhardt, Günther and
Schönenberger, Helmut
(2001)
Does [meso-1,2-bis(2,6-dichloro-4-hydroxy-phenyl) ethylenediamine]dichloroplatinum(II) act as an immune response modifier? IV. Inhibition of the proliferation-increasing effect of progressively growing MXT-M-3,2 breast cancer on phagocytes by the title compound.
Archiv der Pharmazie 334 (10), pp. 309-317.
Fulltext not available.
Gooch, K. J.,
Kwon, J. H.,
Blunk, T.,
Langer, R.,
Freed, L. E. 
and
Vunjak-Novakovic, G. 
(2001)
Effects of mixing intensity on tissue-engineered cartilage.
Biotechnology and Bioengineering 72 (4), pp. 402-407.
Fulltext not available.
Gooch, K.J.,
Blunk, T.,
Courter, D.L.,
Sieminski, A.L.,
Bursac, P.M.,
Vunjak-Novakovic, G. 
and
Freed, L.E. 
(2001)
IGF-I and Mechanical Environment Interact to Modulate Engineered Cartilage Development.
Biochemical and Biophysical Research Communications 286 (5), pp. 909-915.
Fulltext not available.
Iwasa, Kinuko,
Moriyasu, Masataka,
Yamori, Takao,
Turuo, Takashi,
Lee, Dong-Ung and
Wiegrebe, Wolfgang
(2001)
In Vitro Cytotoxicity of the Protoberberine-Type Alkaloids.
Journal of Natural Products 64 (7), pp. 896-898.
Fulltext not available.
Bischoff, Andrea,
Püttmann, Kristina,
Kötting, Annette,
Moser, Christiane,
Buschauer, Armin and
Michel, Martin C.
(2001)
Limited signal transduction repertoire of human Y_5 neuropeptide Y receptors expressed in HEC-B cells.
Peptides 22 (3), pp. 387-394.
Fulltext not available.
Jirovsky, David,
Sellmer, Andreas,
Guiswe, Pierre,
Lemr, Karel 
and
Wiegrebe, Wolfgang
(2001)
On the Stereochemistry of Vincetene.
Monatshefte fuer Chemie/Chemical Monthly 132 (6), pp. 765-768.
Fulltext not available.
Kees, F.,
Färber, L.,
Bucher, M.,
Mair, G.,
Mörike, K. and
Grobecker, H.
(2001)
Pharmacokinetics of therapeutic doses of tropisetron in healthy volunteers.
British Journal of Clinical Pharmacology 52 (6), pp. 705-707.
Fulltext not available.
Vogelhuber, W.,
Rutunno, P.,
Magni, E.,
Gazzaniga, A. 
,
Spruss, Thilo,
Bernhardt, Günther,
Buschauer, Armin and
Goepferich, Achim
(2001)
Programmable biodegradable implants.
Journal of Controlled Release 73 (1), pp. 75-88.
Fulltext not available.
Höcherl, Klaus,
Wolf, Konrad,
Castrop, Hayo,
Ittner, Karl,
Bucher, Michael,
Kees, Frieder,
Grobecker, Horst and
Kurtz, Armin
(2001)
Renocortical expression of renin and of cyclooxygenase-2 in response to angiotensin II AT 1 receptor blockade is closely coordinated but not causally linked.
Pfl�gers Archiv European Journal of Physiology 442 (6), pp. 821-827.
Fulltext not available.
Iwasa, Kinuko,
Moriyasu, Masataka,
Tachibana, Yoko,
Kim, Hye-Sook,
Wataya, Yusuke,
Wiegrebe, Wolfgang,
Bastow, Kenneth F,
Cosentino, L.Mark,
Kozuka, Mutsuo and
Lee, Kuo-Hsiung
(2001)
Simple Isoquinoline and Benzylisoquinoline Alkaloids as Potential Antimicrobial, Antimalarial, Cytotoxic, and Anti-HIV Agents.
Bioorganic & Medicinal Chemistry 9 (11), pp. 2871-2884.
Fulltext not available.
Rostom, Sherif A. F.,
Farghaly, Ahmed M.,
Soliman, Farid S. G.,
El-Semary, Mona M.,
Elz, Sigurd and
Lehmann, Jochen
(2001)
Synthesis and 5-HT2A Antagonist Activity of Derivatives of the Novel Heterocycles Indolo[3,2-d]pyrrolo[3,2-g]azecine and Benzo[d]pyrrolo[3,2-g]azecine compared to the Benz[d]indolo[2,3-g]azecine Derivative LE 300.
Archiv der Pharmazie 334 (7), pp. 241-247.
Fulltext not available.
Mahboobi, Siavosh,
Pongratz, Herwig,
Hufsky, Harald,
Hockemeyer, Jörg,
Frieser, Markus,
Lyssenko, Alexei,
Paper, Dietrich H.,
Bürgermeister, Jutta,
Böhmer, Frank-D.,
Fiebig, Heinz-Herbert,
Burger, Angelika M.,
Baasner, Silke and
Beckers, Thomas
(2001)
Synthetic 2-Aroylindole Derivatives as a New Class of Potent Tubulin-Inhibitory, Antimitotic Agents.
Journal of Medicinal Chemistry 44 (26), pp. 4535-4553.
Fulltext not available.
Meiers, Susanne,
Kemény, Monika,
Weyand, Ulrike,
Gastpar, Robert,
von Angerer, Erwin and
Marko, Doris 
(2001)
The Anthocyanidins Cyanidin and Delphinidin Are Potent Inhibitors of the Epidermal Growth-Factor Receptor.
Journal of Agricultural and Food Chemistry 49 (2), pp. 958-962.
Fulltext not available.
Sazima, M.,
Vogel, S.,
do Prado, A. Lemes,
de Oliveira, D. M.,
Franz, Gerhard and
Sazima, I.
(2001)
The sweet jelly of Combretum lanceolatum flowers (Combretaceae): a cornucopia resource for bird pollinators in the Pantanal, western Brazil.
Plant Systematics and Evolution 227, pp. 195-208.
Fulltext not available.
Zacher, J.,
Burger, K.J.,
Färber, L.,
Gräve, M.,
Abberger, H. and
Bertsch, K.
(2001)
Topisches Diclofenac Emulgel versus orales Ibuprofen in der Therapie der aktivierten Arthrose der Fingergelenke (Heberden- und/oder Bouchard-Arthrose) - Doppelblinde, kontrollierte, randomisierte Studie -.
Aktuelle Rheumatologie 26 (1), pp. 7-14.
Fulltext not available.
Diener, Hans Christoph,
Ringelstein, Erich Bernd,
von Kummer, Rüdiger,
Langohr, Hans Dieter,
Bewermeyer, Heiko,
Landgraf, Helmut,
Hennerici, Michael,
Welzel, Dieter,
Gräve, Michael,
Brom, Joachim and
Weidinger, Gottfried
(2001)
Treatment of Acute Ischemic Stroke With the Low-Molecular-Weight Heparin Certoparin.
Stroke 32 (1), pp. 22-29.
Fulltext not available.
Varga, B.,
Färber, L.,
Kohnen, R.,
Stratz, Th.,
Trocsanyi, M.,
Wild, J. and
Müller, W.
(2000)
4-wöchige Therapie mit dem 5-HT3-Rezeptor-Antagonisten Tropisetron bei der Fibromyalgie.
Aktuelle Rheumatologie 25 (01/02), pp. 43-50.
Fulltext not available.
Lee, Dong-Ung,
Kang, So-Im,
Yoon, Soo-Hong,
Budesinsky, Milos,
Kasal, Alexander,
Mayer, Klaus K. and
Wiegrebe, Wolfgang
(2000)
A New Steroidal Alkaloid from the Roots of Cynanchum caudatum.
Planta Medica 66 (5), pp. 480-482.
Fulltext not available.
Zabel, Manfred,
Breu, Josef 
,
Rau, Franz,
Range, Klaus-Jürgen,
Krey, Volker,
Uffrecht, Anka and
Buschauer, Armin
(2000)
Absolute configuration of (-)-4-(3,4-dichlorophenyl)-4-(2-pyridyl)butanoic acid: essential information to determine crucial steric feature of arpromidine-type histamine H_2 receptor agonists.
Acta Crystallographica Section C 56, pp. 250-251.
Fulltext not available.
Lucke, Andrea,
Teßmar, Jörg 
,
Schnell, Edith,
Schmeer, Georg and
Göpferich, Achim
(2000)
Biodegradable poly(d,l-lactic acid)-poly(ethylene glycol)-monomethyl ether diblock copolymers: structures and surface properties relevant to their use as biomaterials.
Biomaterials 21 (23), pp. 2361-2370.
Fulltext not available.
Schlemmer, Richard,
Spruß, Thilo,
Bernhardt, Günther and
Schönenberger, Helmut
(2000)
Does [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]- dichloro-platinum(II) act as an immune response modifier? Part III: Progressively growing MXT-M-3,2 breast cancer stimulates the proliferation of phagocytes in B6D2F1 mice.
Archiv der Pharmazie 333 (12), pp. 404-414.
Fulltext not available.
Schlemmer, Richard,
Spruß, Thilo,
Bernhardt, Günther and
Schönenberger, Helmut
(2000)
Does [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]- dichloroplatinum(II) act on the hormone-sensitive, murine breast cancer as a biological response modifier? Part 1: The MXT-M-3.2 breast cancer stimulates the growth of an identical second graft; [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]dichloroplat inum (II) inhibits this process.
Archiv der Pharmazie 333 (2-3), pp. 69-71.
Fulltext not available.
Schlemmer, Richard,
Spruß, Thilo,
Bernhardt, Günther and
Schönenberger, Helmut
(2000)
Does [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]- dichloroplatinum(II) act on the hormone-sensitive, murine breast cancer as a biological response modifier? Part II. Studies on the influence of [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine] dichloroplatinum(II) on the specific immune defense in MXT-M-3,2 breast cancer bearing mice.
Archiv der Pharmazie 333 (12), pp. 397-403.
Fulltext not available.
Shafi, Shahida,
Stepanova, Irina P,
Fitzsimmons, C,
Bowyer, D.E,
Welzel, D and
Born, G.V.R
(2000)
Effects of reserpine on expression of the LDL receptor in liver and on plasma and tissue lipids, low density lipoprotein and fibrinogen in rabbits in vivo.
Atherosclerosis 149 (2), pp. 267-275.
Fulltext not available.
Schönberger, Johann,
Bauer, Johann,
Spruß, Thilo,
Weber, Gerhard,
Chahoud, Ibrahim,
Eilles, Christoph and
Grimm, Daniela
(2000)
Establishment and characterization of the follicular thyroid carcinoma cell line ML-1.
Journal of Molecular Medicine 78 (2), pp. 102-110.
Fulltext not available.
Kees, ,
Holstege, ,
Ittner, ,
Zimmermann, ,
Lock, ,
Schölmerich, and
Grobecker,
(2000)
Pharmacokinetic interaction between proton pump inhibitors and roxithromycin in volunteers.
Alimentary Pharmacology & Therapeutics 14 (4), pp. 407-412.
Fulltext not available.
Aiglstorfer, Iris,
Hendrich, Ingo,
Moser, Christiane,
Bernhardt, Günther,
Dove, Stefan and
Buschauer, Armin
(2000)
Structure-Activity Relationships of Neuropeptide Y Y_1 Receptor Antagonists Related to BIBP 3226,.
Bioorganic & Medicinal Chemistry Letters 10 (14), pp. 1597-1600.
Fulltext not available.
Mahboobi, Siavosh,
Dechant, Irene,
Reindl, Hans,
Pongratz, Herwig,
Popp, Alfred and
Schollmeyer, Dieter
(2000)
Synthesis of bis(indolylmaleimide) macrocycles.
Journal of Heterocyclic Chemistry 37 (2), pp. 307-329.
Fulltext not available.
Mahboobi, Siavosh,
Eluwa, Stella,
Koller, Markus,
Popp, Alfred and
Schollmeyer, Dieter
(2000)
Synthesis of pyrrolo[3′,4′:2,3]azepino[4,5,6‐cd]indole‐8,10‐diones.
Journal of Heterocyclic Chemistry 37 (5), pp. 1177-1185.
Fulltext not available.
Ittner, K.P.,
Zimmermann, M.,
Bucher, M.,
Gessele, W.,
Kees, F.,
Krämer, B.K. and
Grobecker, H.F.
(2000)
The effect of urapidil and ramipril on hyperglycemia in streptozotocin diabetic rats.
Naunyn-Schmiedeberg's Archives of Pharmacology 361 (1), pp. 92-97.
Fulltext not available.
Hagelüken, A.,
Grünbaum, L.,
Nürnberg, B.,
Harhammer, R.,
Schunack, W. and
Seifert, Roland
(1994)
Lipophilic beta-adrenoceptor antagonists and local anesthetics are effective direct activators of G-proteins.
Biochemical pharmacology 47 (10), pp. 1789-1795.
Klinker, J. F.,
Hagelüken, A.,
Grünbaum, L.,
Heilmann, I.,
Nürnberg, B.,
Harhammer, R.,
Offermanns, S.,
Schwaner, I.,
Ervens, J.,
Wenzel-Seifert, K.,
Müller, T. and
Seifert, Roland
(1994)
Mastoparan may activate GTP hydrolysis by Gi-proteins in HL-60 membranes indirectly through interaction with nucleoside diphosphate kinase.
The Biochemical journal 304 ( Pt 2, pp. 377-383.
Seifert, Roland,
Hagelüken, A.,
Höer, A.,
Höer, D.,
Grünbaum, L.,
Offermanns, S.,
Schwaner, I.,
Zingel, V.,
Schunack, W. and
Schultz, Günter
(1994)
The H1 receptor agonist 2-(3-chlorophenyl)histamine activates Gi proteins in HL-60 cells through a mechanism that is independent of known histamine receptor subtypes.
Molecular Pharmacology 45 (4), pp. 578-586.
Tsang, K. W.,
Roberts, P.,
Read, R. C.,
Kees, Frieder,
Wilson, R. and
Cole, P. J.
(1994)
The concentrations of clarithromycin and its 14-hydroxy metabolite in sputum of patients with bronchiectasis following single dose oral administration.
The Journal of antimicrobial chemotherapy 33 (2), pp. 289-297.
Klinker, J. F.,
Höer, A.,
Schwaner, I.,
Offermanns, S.,
Wenzel-Seifert, Katharina and
Seifert, Roland
(1993)
Lipopeptides activate Gi-proteins in dibutyryl cyclic AMP-differentiated HL-60 cells.
The Biochemical journaL 296 ( Pt 1, pp. 245-251.
Klinz, F. J.,
Seifert, Roland,
Schwaner, I.,
Gausepohl, H.,
Frank, R. and
Schultz, Günter
(1992)
Generation of specific antibodies against the rap1A, rap1B and rap2 small GTP-binding proteins. Analysis of rap and ras proteins in membranes from mammalian cells.
European journal of biochemistry 207 (1), pp. 207-213.
Seifert, Roland,
Serke, S.,
Huhn, D.,
Bessler, W. G.,
Hauschildt, S.,
Metzger, J.,
Wismüller, K. H. and
Jung, G.
(1992)
Incomplete functional differentiation of HL-60 leukemic cells by synthetic lipopeptides. Partial inhibition by pertussis toxin of enhanced superoxide formation.
European journal of biochemistry / FEBS 203 (1-2), pp. 143-151.
Offermanns, S.,
Seifert, Roland,
Metzger, J. W.,
Jung, G.,
Lieberknecht, A.,
Schmidt, U. and
Schultz, Günter
(1992)
Lipopeptides are effective stimulators of tyrosine phosphorylation in human myeloid cells.
Biochemical Journal 282 ( Pt 2, pp. 551-7.
Seifert, Roland,
Schultz, Günter,
Richter-Freund, M.,
Metzger, J.,
Wiesmüller, K. H.,
Jung, G.,
Bessler, W. G. and
Hauschildt, S.
(1990)
Activation of superoxide formation and lysozyme release in human neutrophils by the synthetic lipopeptide Pam3Cys-Ser-(Lys)4. Involvement of guanine-nucleotide-binding proteins and synergism with chemotactic peptides.
The Biochemical journal 267 (3), pp. 795-802.
Naber, K. G.,
Sörgel, F.,
Kees, Frieder K.,
Schumacher, H.,
Sigl, G.,
Zürcher, J. and
Berger, S.
(1989)
Enoxacin-Konzentrationen in der Samenflüssigkeit, im Prostatasekret und im Prostataadenomgewebe nach oraler Gabe oder intravenöser Infusion [Enoxacin concentration in seminal fluid, in prostate secretions and in prostatic adenoma tissue following oral administration or intravenous infusion].
Infection 17 Suppl 1, S30-S66.
Rudolph, U.,
Koesling, D.,
Hinsch, K. D.,
Seifert, Roland,
Bigalke, M.,
Schultz, Günter and
Rosenthal, W.
(1989)
G-protein alpha-subunits in cytosolic and membranous fractions of human neutrophils.
Molecular and cellular endocrinology 63 (1-2), pp. 143-153.
Naber, K. G.,
Sörgel, F.,
Kees, Frieder K.,
Jaehde, U. and
Schumacher, H.
(1989)
Pharmacokinetics of ciprofloxacin in young (healthy volunteers) and elderly patients, and concentrations in prostatic fluid, seminal fluid, and prostatic adenoma tissue following intravenous administration.
The American journal of medicine 87 (5supl1), S57-S59.
Naber, K. G.,
Sörgel, F.,
Kees, Frieder K.,
Schumacher, H.,
Metz, R. and
Grobecker, H.
(1988)
In-vitro activity of fleroxacin against isolates causing complicated urinary tract infections and concentrations in seminal and prostatic fluid and in prostatic adenoma tissue.
The Journal of antimicrobial chemotherapy 22 Suppl D, pp. 199-207.
Seifert, Roland,
Rosenthal, W.,
Schultz, Günter,
Wieland, T.,
Gierschick, P. and
Jakobs, K. H.
(1988)
The role of nucleoside-diphosphate kinase reactions in G protein activation of NADPH oxidase by guanine and adenine nucleotides.
European journal of biochemistry / FEBS 175 (1), pp. 51-55.
Naber, K.,
Kees, Frieder K.,
Denk, K.,
Bauernfeind, A. and
Grobecker, H.
(1987)
Carumonam versus ceftazidime: in vitro activity, pharmacokinetics in elderly patients, safety and therapeutic efficacy in the treatment of complicated urinary tract infections.
Chemioterapia 6 (2 Supl), pp. 517-518.
Fulltext not available.
Grobecker, H.,
Kees, Frieder K.,
Linden, M.,
Schrader, E. and
Welte, S.
(1987)
Untersuchungen zur Bioverfügbarkeit von Midodrin und 2,5- Dimethoxyphenyl-ß-aminoethanol-hydrochlorid [The bioavailability of midodrin and alpha-2,5-dimethoxyphenyl-beta-aminoethanol hydrochloride].
Arzneimittel-Forschung 37 (4), pp. 447-450.
Naber, K. G.,
Dette, G. A.,
Kees, Frieder K.,
Knothe, H. and
Grobecker, H.
(1986)
Pharmacokinetics, in-vitro activity, therapeutic efficacy and clinical safety of aztreonam vs. cefotaxime in the treatment of complicated urinary tract infections.
The Journal of antimicrobial chemotherapy 17 (4), pp. 517-527.
Grobecker, H.,
Gessler, I.,
Delius, W.,
Dominiak, P. and
Kees, Frieder K.
(1985)
Effect of ketanserin on hemodynamics, plasma-catecholamine concentrations, and serotonin uptake by platelets in volunteers and patients with congestive heart failure.
Journal of cardiovascular pharmacology 7, Suppl 7, S102-S104.
Kees, Frieder K.,
Naber, K. G.,
Bartoschik-Wich, B.,
Stockmann, P.,
Meyer, G. P. and
Grobecker, H.
(1985)
High-performance liquid chromatography analysis of mezlocillin, piperacillin, their degradation products, and of ioxitalamic acid in plasma and urine of healthy volunteers.
Arzneimittel-Forschung 35 (7), pp. 1099-1104.
Kees, Frieder K.,
Strehl, E.,
Dominiak, P.,
Grobecker, H.,
Seeger, K.,
Seidel, G.,
Neuhaus, B. and
Safrany, L.
(1983)
Cefotaxime and desacetyl cefotaxime in human bile.
Infection 11 (2), pp. 118-120.
Kees, Frieder K.,
Strehl, E.,
Seeger, K.,
Seidel, G.,
Dominiak, P. and
Grobecker, H.
(1981)
Comparative determination of cefotaxime and desacetyl cefotaxime in serum and bile by bioassay and high-performance liquid chromatography.
Arzneimittel-Forschung 31 (2), pp. 362-365.
This list was generated on Tue May 20 06:31:40 2025 CEST.