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Quality assurance in the pre-analytical phase of human urine samples by 1H NMR spectroscopy

Budde, Kathrin ; Gök, Ömer-Necmi ; Pietzner, Maik ; Meisinger, Christine ; Leitzmann, Michael ; Nauck, Matthias ; Köttgen, Anna ; Friedrich, Nele


Metabolomic approaches investigate changes in metabolite profiles, which may reflect changes in metabolic pathways and provide information correlated with a specific biological process or pathophysiology. High-resolution H-1 NMR spectroscopy is used to identify metabolites in biofluids and tissue samples qualitatively and quantitatively. This pre-analytical study evaluated the effects of storage ...


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