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Diabetes, use of antidiabetic drugs, and the risk of glioma

Seliger, Corinna ; Ricci, Cristian ; Meier, Christoph R. ; Bodmer, Michael ; Jick, Susan S. ; Bogdahn, Ulrich ; Hau, Peter ; Leitzmann, Michael F.


Prior epidemiologic studies suggest inverse relations between diabetes and glioma risk, but the underlying mechanisms, including use of antidiabetic drugs, are unknown. We therefore performed a matched case-control analysis using the Clinical Practice Research Datalink (CPRD). We identified incident glioma cases diagnosed between 1995 and 2012 and matched each case with 10 controls on age, ...


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