Go to content
UR Home

Structural basis of RNA polymerase I pre-initiation complex formation and promoter melting

URN to cite this document:
DOI to cite this document:
Pilsl, Michael ; Engel, Christoph
License: Creative Commons Attribution 4.0
PDF - Published Version
Date of publication of this fulltext: 09 Apr 2020 16:33


Transcription of the ribosomal RNA precursor by RNA polymerase (Pol) I is a prerequisite for the biosynthesis of ribosomes in eukaryotes. Compared to Pols II and III, the mechanisms underlying promoter recognition, initiation complex formation and DNA melting by Pol I substantially diverge. Here, we report the high-resolution cryo-EM reconstruction of a Pol I early initiation intermediate ...


Owner only: item control page
  1. Homepage UR

University Library

Publication Server


Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons