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Wein, Simon ; Tomé, Ana M. ; Goldhacker, Markus ; Greenlee, Mark W. ; Lang, Elmar W.

A Constrained ICA-EMD Model for Group Level fMRI Analysis

Article

Wein, Simon, Tomé, Ana M., Goldhacker, Markus , Greenlee, Mark W. and Lang, Elmar W. (2020) A Constrained ICA-EMD Model for Group Level fMRI Analysis. Frontiers in Neuroscience 14 (221), pp. 1-10.

DOI to cite this document: 10.5283/epub.43197


Abstract

Independent component analysis (ICA), being a data-driven method, has been shown to be a powerful tool for functional magnetic resonance imaging (fMRI) data analysis. One drawback of this multivariate approach is that it is not, in general, compatible with the analysis of group data. Various techniques have been proposed to overcome this limitation of ICA. In this paper, a novel ICA-based ...

Independent component analysis (ICA), being a data-driven method, has been shown to be a powerful tool for functional magnetic resonance imaging (fMRI) data analysis. One drawback of this multivariate approach is that it is not, in general, compatible with the analysis of group data. Various techniques have been proposed to overcome this limitation of ICA. In this paper, a novel ICA-based workflow for extracting resting-state networks from fMRI group studies is proposed. An empirical mode decomposition (EMD) is used, in a data-driven manner, to generate reference signals that can be incorporated into a constrained version of ICA (cICA), thereby eliminating the inherent ambiguities of ICA. The results of the proposed workflow are then compared to those obtained by a widely used group ICA approach for fMRI analysis. In this study, we demonstrate that intrinsic modes, extracted by EMD, are suitable to serve as references for cICA. This approach yields typical resting-state patterns that are consistent over subjects. By introducing these reference signals into the ICA, our processing pipeline yields comparable activity patterns across subjects in a mathematically transparent manner. Our approach provides a user-friendly tool to adjust the trade-off between a high similarity across subjects and preserving individual subject features of the independent components.



Involved Institutions


Details

Item typeArticle
Journal or Publication TitleFrontiers in Neuroscience
PublisherFrontiers
Open Access TypeGold (with APC)
Place of PublicationLAUSANNE
Volume14
Number of Issue or Book Chapter221
Page Rangepp. 1-10
Date15 April 2020
Date of publication14 May 2020 11:29
InstitutionsHuman Sciences > Institut für Psychologie > Lehrstuhl für Psychologie I (Allgemeine Psychologie I und Methodenlehre) - Prof. Dr. Mark W. Greenlee
Biology, Preclinical Medicine > Institut für Biophysik und physikalische Biochemie > Prof. Dr. Elmar Lang
Identification Number
ValueType
10.3389/fnins.2020.00221DOI
KeywordsINDEPENDENT COMPONENT ANALYSIS; BLIND SOURCE SEPARATION; FUNCTIONAL MRI DATA; TIME-SERIES; DECOMPOSITION; CONNECTIVITY; ALGORITHMS; INFERENCES; NETWORK; INFOMAX; independent component analysis; ICA; empirical mode decomposition; EMD; Green's-function; based EMD; fMRI
Dewey Decimal Classification100 Philosophy & psychology > 150 Psychology
500 Science > 570 Life sciences
StatusPublished
RefereedYes, this version has been refereed
Created at the University of RegensburgYes
URN of the UB Regensburgurn:nbn:de:bvb:355-epub-431976
Item ID43197

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