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Wein, Simon ; Tomé, Ana M. ; Goldhacker, Markus ; Greenlee, Mark W. ; Lang, Elmar W.

A Constrained ICA-EMD Model for Group Level fMRI Analysis

Wein, Simon, Tomé, Ana M., Goldhacker, Markus , Greenlee, Mark W. und Lang, Elmar W. (2020) A Constrained ICA-EMD Model for Group Level fMRI Analysis. Frontiers in Neuroscience 14 (221), S. 1-10.

Veröffentlichungsdatum dieses Volltextes: 14 Mai 2020 11:29
Artikel
DOI zum Zitieren dieses Dokuments: 10.5283/epub.43197


Zusammenfassung

Independent component analysis (ICA), being a data-driven method, has been shown to be a powerful tool for functional magnetic resonance imaging (fMRI) data analysis. One drawback of this multivariate approach is that it is not, in general, compatible with the analysis of group data. Various techniques have been proposed to overcome this limitation of ICA. In this paper, a novel ICA-based ...

Independent component analysis (ICA), being a data-driven method, has been shown to be a powerful tool for functional magnetic resonance imaging (fMRI) data analysis. One drawback of this multivariate approach is that it is not, in general, compatible with the analysis of group data. Various techniques have been proposed to overcome this limitation of ICA. In this paper, a novel ICA-based workflow for extracting resting-state networks from fMRI group studies is proposed. An empirical mode decomposition (EMD) is used, in a data-driven manner, to generate reference signals that can be incorporated into a constrained version of ICA (cICA), thereby eliminating the inherent ambiguities of ICA. The results of the proposed workflow are then compared to those obtained by a widely used group ICA approach for fMRI analysis. In this study, we demonstrate that intrinsic modes, extracted by EMD, are suitable to serve as references for cICA. This approach yields typical resting-state patterns that are consistent over subjects. By introducing these reference signals into the ICA, our processing pipeline yields comparable activity patterns across subjects in a mathematically transparent manner. Our approach provides a user-friendly tool to adjust the trade-off between a high similarity across subjects and preserving individual subject features of the independent components.



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Details

DokumentenartArtikel
Titel eines Journals oder einer ZeitschriftFrontiers in Neuroscience
Verlag:Frontiers
Ort der Veröffentlichung:LAUSANNE
Band:14
Nummer des Zeitschriftenheftes oder des Kapitels:221
Seitenbereich:S. 1-10
Datum15 April 2020
InstitutionenHumanwissenschaften > Institut für Psychologie > Lehrstuhl für Psychologie I (Allgemeine Psychologie I und Methodenlehre) - Prof. Dr. Mark W. Greenlee
Biologie und Vorklinische Medizin > Institut für Biophysik und physikalische Biochemie > Prof. Dr. Elmar Lang
Identifikationsnummer
WertTyp
10.3389/fnins.2020.00221DOI
Stichwörter / KeywordsINDEPENDENT COMPONENT ANALYSIS; BLIND SOURCE SEPARATION; FUNCTIONAL MRI DATA; TIME-SERIES; DECOMPOSITION; CONNECTIVITY; ALGORITHMS; INFERENCES; NETWORK; INFOMAX; independent component analysis; ICA; empirical mode decomposition; EMD; Green's-function; based EMD; fMRI
Dewey-Dezimal-Klassifikation100 Philosophie und Psychologie > 150 Psychologie
500 Naturwissenschaften und Mathematik > 570 Biowissenschaften, Biologie
StatusVeröffentlicht
BegutachtetJa, diese Version wurde begutachtet
An der Universität Regensburg entstandenJa
URN der UB Regensburgurn:nbn:de:bvb:355-epub-431976
Dokumenten-ID43197

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