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From structure to function: route to understanding lncRNA mechanism

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Graf, Johannes ; Kretz, Markus
Date of publication of this fulltext: 27 Jan 2021 13:44

This publication is part of the DEAL contract with Wiley.


RNAs have emerged as a major target for diagnostics and therapeutics approaches. Regulatory nonprotein-coding RNAs (ncRNAs) in particular display remarkable versatility. They can fold into complex structures and interact with proteins, DNA, and other RNAs, thus modulating activity, localization, or interactome of multi-protein complexes. Thus, ncRNAs confer regulatory plasticity and represent a ...


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