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From structure to function: route to understanding lncRNA mechanism

URN to cite this document:
urn:nbn:de:bvb:355-epub-446350
DOI to cite this document:
10.5283/epub.44635
Graf, Johannes ; Kretz, Markus
Date of publication of this fulltext: 27 Jan 2021 13:44


Abstract

RNAs have emerged as a major target for diagnostics and therapeutics approaches. Regulatory nonprotein-coding RNAs (ncRNAs) in particular display remarkable versatility. They can fold into complex structures and interact with proteins, DNA, and other RNAs, thus modulating activity, localization, or interactome of multi-protein complexes. Thus, ncRNAs confer regulatory plasticity and represent a ...

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