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Design of Protein Interfaces Using Computer-Based Methods

URN to cite this document:
urn:nbn:de:bvb:355-epub-448842
DOI to cite this document:
10.5283/epub.44884
Nazet, Julian Simon
Date of publication of this fulltext: 01 Mar 2022 07:27


Abstract (English)

Computer-based methods are excellent tools to modify existing proteins. The software suite Rosetta offers a large variety of options to solve many problems of protein design. During the last decades a steadily increasing number of protocols became available and more complex concepts for the modelling of proteins and their function arouse. Among them is multi-state protein design (MSD) that ...

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Translation of the abstract (German)

Computergestützte Methoden sind hervorragende Werkzeuge, um vorhandene Proteine zu modifizieren. Die Software-Suite Rosetta bietet eine Vielzahl von Optionen, um viele Probleme des Proteindesigns zu lösen. Während der letzten Jahrzehnte lang wurde eine stetig wachsende Anzahl von Protokollen und komplexeren Konzepten zur Modellierung von Proteinen und deren Funktion verfügbar. Unter ihnen ist ...

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