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- URN to cite this document:
- urn:nbn:de:bvb:355-epub-455608
- DOI to cite this document:
- 10.5283/epub.45560
Peters, Sebastian 
; Kuespert, Sabrina ; Wirkert, Eva ; Heydn, Rosmarie ; Jurek, Benjamin ; Johannesen, Siw ; Hsam, Ohnmar ; Korte, Sven ; Ludwig, Florian Timo ; Mecklenburg, Lars ; Mrowetz, Heike ; Altendorfer, Barbara ; Poupardin, Rodolphe ; Petri, Susanne ; Thal, Dietmar R. ; Hermann, Andreas ; Weishaupt, Jochen H. ; Weis, Joachim ; Aksoylu, Inci Sevval ; Lewandowski, Sebastian A. ; Aigner, Ludwig ; Bruun, Tim-Henrik ; Bogdahn, Ulrich
; Kuespert, Sabrina ; Wirkert, Eva ; Heydn, Rosmarie ; Jurek, Benjamin ; Johannesen, Siw ; Hsam, Ohnmar ; Korte, Sven ; Ludwig, Florian Timo ; Mecklenburg, Lars ; Mrowetz, Heike ; Altendorfer, Barbara ; Poupardin, Rodolphe ; Petri, Susanne ; Thal, Dietmar R. ; Hermann, Andreas ; Weishaupt, Jochen H. ; Weis, Joachim ; Aksoylu, Inci Sevval ; Lewandowski, Sebastian A. ; Aigner, Ludwig ; Bruun, Tim-Henrik ; Bogdahn, Ulrich Abstract
Adult neurogenesis is a target for brain rejuvenation as well as regeneration in aging and disease. Numerous approaches showed efficacy to elevate neurogenesis in rodents, yet translation into therapies has not been achieved. Here, we introduce a novel human TGFβ-RII (Transforming Growth Factor—Receptor Type II) specific LNA-antisense oligonucleotide (“locked nucleotide acid”—“NVP-13”), which ...
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