Angerer, S. von, Seidl, E., Mannschreck, A., Angerer, E. von and Wiegrebe, Wolfgang (1994) Dibenzo[a,f]quinolizines: syntheses and cytostatic activity in estrogen-sensitive tumor cells. Anti-cancer drug design 9 (1), pp. 25-40.
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Abstract
A number of methoxy-substituted 7,11b,12,13-tetrahydro-6H-dibenzo-[a,f]quinolizines with short alkyl groups in position 6 or 12 were synthesized by the Bischler-Napieralski reaction using the appropriate starting material followed by a second ring closure reaction involving a base-generated benzyne intermediate. The methoxy functions in positions 2 or 3 and 9 were cleaved with BBr3 and the free ...
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| Item type: | Article | ||||||||||||||||||||||||||
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| Date: | 1994 | ||||||||||||||||||||||||||
| Institutions: | Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Oliver Reiser Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer) | ||||||||||||||||||||||||||
| Projects: | SFB 234 | ||||||||||||||||||||||||||
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| Classification: |
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| Dewey Decimal Classification: | 500 Science > 570 Life sciences 500 Science > 540 Chemistry & allied sciences 600 Technology > 610 Medical sciences Medicine | ||||||||||||||||||||||||||
| Status: | Published | ||||||||||||||||||||||||||
| Refereed: | Yes, this version has been refereed | ||||||||||||||||||||||||||
| Created at the University of Regensburg: | Yes | ||||||||||||||||||||||||||
| Item ID: | 4766 |
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