Go to content
UR Home

Tumor inhibiting [1,2-bis(fluorophenyl)ethylenediamine]platinum(II) complexes. Part II: Biological evaluation-in vitro studies on the P 388 D1 leukemia cell line

URN to cite this document:
urn:nbn:de:bvb:355-epub-48329
DOI to cite this document:
10.5283/epub.4832
Reile, Herta ; Müller, Richard ; Gust, Ronald ; Laske, Reiner ; Krischke, Walter ; Bernhardt, Günther ; Spruss, Thilo ; Jennerwein, Margaretha ; Engel, Jürgen ; Seeber, Siegfried
[img]
Preview
PDF
(775kB)
Date of publication of this fulltext: 05 Aug 2009 13:48


Abstract

Experiments on the P 388 D1 cell line (48 h exposure) demonstrate that [1,2-bis-(fluorophenyl)ethylenediamine]platinum(II) complexes are comparably active on the cell number and 3H-thymidine incorporation, irrespective of the position of the fluorine atom (ortho, meta, or para) and the nature of the "leaving group" (Cl- or H2O). However, the compounds of the R,R/S,S series are more active than ...

plus


Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons