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Anesthesia of the conditioned limb does not abolish the remote ischemic conditioning stimulus on cutaneous microcirculation in humans

Ederer, I. A. ; Goertz, O. ; Bosselmann, T. ; Sogorski, A. ; Zahn, P. K. ; Lehnhardt, M. ; Daigeler, A. ; Kolbenschlag, J.


BACKGROUND: Mechanism of remote ischemic conditioning (RIC) remain not fully understood yet. Thus, a clinical trial was performed to assess the neuronal influence on its signal induction. METHODS: RIC was conducted on 45 patients who were randomized into 3 groups. Group A and B underwent brachial plexus anesthesia while RIC was performed on the blocked (A) and non-blocked side (B), respectively. ...


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