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Association of polymorphous light eruption with NOD ‐2 and TLR ‐5 gene polymorphisms

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Kurz, B. ; Arndt, S. ; Unger, P. ; Ivanova, I. ; Berneburg, Mark ; Hellerbrand, C. ; Karrer, Sigrid
Date of publication of this fulltext: 20 Oct 2022 06:19

This publication is part of the DEAL contract with Wiley.


Background Polymorphous light eruption (PLE) is a common, immunologically mediated, photosensitive skin disease. After ultraviolet-B (UV-B) irradiation, patients with PLE show reduced Langerhans cell (LC) depletion in the epidermis, which results in a non-suppressive microenvironment in the skin. Interestingly, severe acute graft-versus-host disease (aGvHD) occurred in stem cell transplanted ...


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