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Targeted therapies in patients with newly diagnosed glioblastoma - a systematic meta-analysis of randomized clinical trials

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Scherm, Angelika ; Ippen, Franziska Maria ; Hau, Peter ; Baurecht, Hansjörg ; Wick, Wolfgang ; Gempt, Jens ; Knüttel, Helge ; Leitzmann, Michael ; Seliger, Corinna

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Date of publication of this fulltext: 06 Feb 2023 07:19


Glioblastoma (GB) is the most common malignant primary brain tumor in adults. The standard of care for newly diagnosed GB involves surgical resection followed by radiochemotherapy with temozolomide, with or without tumor-treating fields. In recent years, various efforts have been made to identify suitable molecularly targeted treatment options for malignant brain tumors. This meta-analysis ...


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