Go to content
UR Home

Picolinic Acids as Inhibitors of Dopamine b-Monooxygenase: QSAR and Putative Binding Site

Dove, Stefan


Dopamine b-monooxygenase (DBM, EC catalyzes the oxidn. of dopamine into (R)-noradrenaline. DBM inhibitors may act as antihypertensive drugs. A series of 22 picolinic acids substituted in 4- and 5-position was previously synthesized and tested for inhibition of DBM from bovine adrenal medulla. The QSAR of these compds. were investigated by Hansch anal. and comparative mol. field ...


Owner only: item control page
  1. Homepage UR

University Library

Publication Server


Publishing: oa@ur.de

Dissertations: dissertationen@ur.de

Research data: daten@ur.de

Contact persons