Go to content
UR Home

4,6-Di(heteroaryl)-2-(N-methylpiperazino)pyrimidines as New, Potent 5-HT2A Receptor Ligands: A Verification of the Topographic Model

Mokrosz, M.J., Strekowski, L., Kosak, W.X., Duszynska, B., Bojarski, A.J., Klodzinska, A., Czarny, A., Cegla, M.T., Deren-Wesolek, A., Chojnacka-Wojcik, E., Dove, Stefan and Mokrosz, J.L. (1995) 4,6-Di(heteroaryl)-2-(N-methylpiperazino)pyrimidines as New, Potent 5-HT2A Receptor Ligands: A Verification of the Topographic Model. Archiv der Pharmazie 328 (9), pp. 659-666.

Full text not available from this repository.

Other URL: http://www3.interscience.wiley.com/journal/113348924/abstract


Abstract

A series of new 4,6-di(heteroaryl)pyrimidines containing an N-methylpiperazino group (6-13) or an ethylenediamine chain (15-20) in position 2 were synthesized and their 5-HT1A and 5-HT2A receptor affinities were determined. It was shown that the substituent effects on the 5-HT2A affinity are additive and could be described quantitatively. In a behavioral model it was also demonstrated that 6-11 ...

plus


Export bibliographical data



Item type:Article
Date:1995
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)
Dewey Decimal Classification:500 Science > 570 Life sciences
500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:5453
Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de

Dissertations: dissertationen@ur.de

Research data: daten@ur.de

Contact persons