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Darstellung einiger 4- und 5-substituierter Pyridin-2-Carbonsäuren als Fusarsäureanaloga

Oehlke, J. ; Schrötter, E. ; Dove, Stefan ; Schick, H. ; Niedrich, H.


5-Substituted picolinic acids I (R = NO2, NH2, NHAc, NHCOEt, NHOH, iodo, Br, OH, MeO, PrO, BuO; R1 = H) and 4-substituted fusaric acids I (R = Bu, R1 = NO2, MeO, EtO, Cl, NH2, NHOH, Me), selected by a random sampling procedure suitable for small series, were prepd. for future studies on the structure-activity relationships involved in the inhibition of dopamine b-hydroxylase. The known prepn. of ...


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