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Walter, Nike ; Szymski, Dominik ; Kurtz, Steven M. ; Lowenberg, David W. ; Alt, Volker ; Lau, Edmund C. ; Rupp, Markus

Complications and associated risk factors after surgical management of proximal femoral fractures

Article

Walter, Nike , Szymski, Dominik , Kurtz, Steven M., Lowenberg, David W., Alt, Volker , Lau, Edmund C. and Rupp, Markus (2023) Complications and associated risk factors after surgical management of proximal femoral fractures. Bone & Joint Open 4 (10), pp. 801-807.

DOI to cite this document: 10.5283/epub.54910


Abstract

Aims This work aimed at answering the following research questions: 1) What is the rate of mechanical complications, nonunion and infection for head/neck femoral fractures, intertrochanteric fractures, and subtrochanteric fractures in the elderly USA population? and 2) Which factors influence adverse outcomes? Methods Proximal femoral fractures occurred between 1 January 2009 and 31 ...

Aims

This work aimed at answering the following research questions: 1) What is the rate of mechanical complications, nonunion and infection for head/neck femoral fractures, intertrochanteric fractures, and subtrochanteric fractures in the elderly USA population? and 2) Which factors influence adverse outcomes?
Methods

Proximal femoral fractures occurred between 1 January 2009 and 31 December 2019 were identified from the Medicare Physician Service Records Data Base. The Kaplan-Meier method with Fine and Gray sub-distribution adaptation was used to determine rates for nonunion, infection, and mechanical complications. Semiparametric Cox regression model was applied incorporating 23 measures as covariates to identify risk factors.
Results

Union failure occured in 0.89% (95% confidence interval (CI) 0.83 to 0.95) after head/neck fracturs, in 0.92% (95% CI 0.84 to 1.01) after intertrochanteric fracture and in 1.99% (95% CI 1.69 to 2.33) after subtrochanteric fractures within 24 months. A fracture-related infection was more likely to occur after subtrochanteric fractures than after head/neck fractures (1.64% vs 1.59%, hazard ratio (HR) 1.01 (95% CI 0.87 to 1.17); p < 0.001) as well as after intertrochanteric fractures (1.64% vs 1.13%, HR 1.31 (95% CI 1.12 to 1.52); p < 0.001). Anticoagulant use, cerebrovascular disease, a concomitant fracture, diabetes mellitus, hypertension, obesity, open fracture, and rheumatoid disease was identified as risk factors. Mechanical complications after 24 months were most common after head/neck fractures with 3.52% (95% CI 3.41 to 3.64; currently at risk: 48,282).
Conclusion

The determination of complication rates for each fracture type can be useful for informed patient-clinician communication. Risk factors for complications could be identified for distinct proximal femur fractures in elderly patients, which are accessible for therapeutical treatment in the management.



Involved Institutions


Details

Item typeArticle
Journal or Publication TitleBone & Joint Open
PublisherBritish Editorial Society of Bone & Joint Surgery
Open Access TypeGold (with APC)
Volume4
Number of Issue or Book Chapter10
Page Rangepp. 801-807
Date23 October 2023
Date of publication24 Oct 2023 08:42
InstitutionsMedicine > Lehrstuhl für Unfallchirurgie
Identification Number
ValueType
10.1302/2633-1462.410.BJO-2023-0088.R1DOI
KeywordsProximal femur fracture, Risk factors, Complications, Union failure, Fracture-related infection, Proximal femur fractures (PFFs), fracture-related infections, intertrochanteric fractures, subtrochanteric fractures, mechanical complications, neck fractures, femoral fractures, infection, rheumatoid disease, hypertension
Dewey Decimal Classification600 Technology > 610 Medical sciences Medicine
StatusPublished
RefereedYes, this version has been refereed
Created at the University of RegensburgYes
URN of the UB Regensburgurn:nbn:de:bvb:355-epub-549108
Item ID54910

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