Determination of glomerular filtration rate “en passant” after high doses of iohexol for computed tomography in intensive care medicine—a proof of concept

URN to cite this document:: urn:nbn:de:bvb:355-epub-555123
DOI to cite this document:: 10.5283/epub.55512

Dejaco, Alexander

; Dorn, Christoph

; Paal, Michael ; Gruber, Michael

; Graf, Bernhard M. ; Kees, Martin G.

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 06 Feb 2024 08:10

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Abstract

Accurate assessment of renal function is of great clinical and scientific importance, as it is an important pharmacokinetic covariate of pivotal drugs. The iohexol clearance is nearly identical to the glomerular filtration rate, but its determination usually requires an intravenous injection and therefore bears intrinsic risks. This motivates to showcase an “en passant” approach to quantification ...