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Periodontitis and pulmonary function: a Mendelian randomization study

Baumeister, Sebastian-Edgar ; Nolde, Michael ; Holtfreter, Birte ; Baurecht, Hansjörg ; Gläser, Sven ; Kocher, Thomas ; Ehmke, Benjamin




Abstract

Objectives Observational research suggests that periodontitis affects pulmonary function; however, observational studies are subject to confounding and reverse causation, making causal inference and the direction of these associations difficult. We used Mendelian randomization (MR) to assess the potential causal association between genetic liability to periodontitis and pulmonary function. ...

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