Analysis of Osteosarcoma Cell Lines and Patient Tissue Using a 3D In Vivo Tumor Model—Possible Effects of Punicalagin

URN to cite this document:: urn:nbn:de:bvb:355-epub-578638
DOI to cite this document:: 10.5283/epub.57863

Dorn, Anna Rebecca ; Neff, Sara

; Hupp, Sophia ; Engelhardt, Melissa ; Pion, Eric ; Lenze, Ulrich ; Knebel, Carolin

; Duprée, Anna ; Schewe, Simone ; Weber, Markus

; Wulbrand, Christian ; Hillmann, Axel ; Weber, Florian

; Clarke, Phillip ; Kainz, Philipp

; Aung, Thiha ; Haerteis, Silke

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 04 Apr 2024 11:32

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Abstract

Osteosarcomas are the most common primary malignant bone tumors and mostly affect children, adolescents, and young adults. Despite current treatment options such as surgery and polychemotherapy, the survival of patients with metastatic disease remains poor. In recent studies, punicalagin has reduced the cell viability, angiogenesis, and invasion in cell culture trials. The aim of this study was ...