Restricting datasets to classifiable samples augments discovery of immune disease biomarkers

URN to cite this document:: urn:nbn:de:bvb:355-epub-585399
DOI to cite this document:: 10.5283/epub.58539

Glehr, Gunther

; Riquelme, Paloma

; Kronenberg, Katharina ; Lohmayer, Robert ; López-Madrona, Víctor J. ; Kapinsky, Michael ; Schlitt, Hans J.

; Geissler, Edward K.

; Spang, Rainer ; Haferkamp, Sebastian

; Hutchinson, James A.

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 27 Jun 2024 13:59

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Abstract

Immunological diseases are typically heterogeneous in clinical presentation, severity and response to therapy. Biomarkers of immune diseases often reflect this variability, especially compared to their regulated behaviour in health. This leads to a common difficulty that frustrates biomarker discovery and interpretation – namely, unequal dispersion of immune disease biomarker expression between ...