Development of a Galleria mellonella Infection Model to Evaluate the Efficacy of Antibiotic-Loaded Polymethyl Methacrylate (PMMA) Bone Cement

URN to cite this document:: urn:nbn:de:bvb:355-epub-591186
DOI to cite this document:: 10.5283/epub.59118

Zhao, You

; Mannala, Gopala Krishna

; Youf, Raphaëlle

; Rupp, Markus

; Alt, Volker

; Riool, Martijn

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 10 Sep 2024 04:25

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Abstract

Prosthetic joint infections (PJIs) can have disastrous consequences for patient health, including removal of the device, and placement of cemented implants is often required during surgery to eradicate PJIs. In translational research, in vivo models are widely used to assess the biocompatibility and antimicrobial efficacy of antimicrobial coatings and compounds. Here, we aim to utilize Galleria ...