Target-site cefiderocol pharmacokinetics in soft tissues of healthy volunteers

URN to cite this document:: urn:nbn:de:bvb:355-epub-598109
DOI to cite this document:: 10.5283/epub.59810

Sanz-Codina, Maria ; van Os, Wisse ; Pham, Anh Duc ; Jorda, Anselm ; Wölf-Duchek, Michael ; Bergmann, Felix ; Lackner, Edith ; Lier, Constantin ; Coen van Hasselt, J. G. ; Minichmayr, Iris K. ; Dorn, Christoph

; Zeitlinger, Markus ; al Jalali, Valentin

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 17 Dec 2024 09:05

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Abstract

Background: Cefiderocol may potentially be used to treat skin and soft tissue infections (SSTIs). However, the pharmacokinetics of cefiderocol in human soft tissues have not yet been determined. The objective of the present PK study was to investigate whether target-site concentrations of cefiderocol are sufficiently high for the treatment of SSTIs. Methods: In this pharmacokinetic study, a ...