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Weber, Franziska C. ; Engelke, Milena ; Kerkel, Katharina ; Langguth, Berthold

Is the rate of depression in tinnitus overestimated? A comparison of categorical and dimensional analyses of the Major Depression Inventory

Weber, Franziska C. , Engelke, Milena , Kerkel, Katharina und Langguth, Berthold (2026) Is the rate of depression in tinnitus overestimated? A comparison of categorical and dimensional analyses of the Major Depression Inventory. Journal of Psychosomatic Research 207, S. 112679.

Veröffentlichungsdatum dieses Volltextes: 24 Apr 2026 08:12
Artikel
DOI zum Zitieren dieses Dokuments: 10.5283/epub.79318


Zusammenfassung

Background: Previous investigations have demonstrated a high rate of depression in patients with severe tinnitus. In most studies, sum scores have been used for diagnosing depression, and it remains debated whether these scores reflect a comorbid depressive disorder or rather distress caused by tinnitus. Methods: To determine whether this elevated rate may partly result from symptom overlap ...

Background:
Previous investigations have demonstrated a high rate of depression in patients with severe tinnitus. In most studies, sum scores have been used for diagnosing depression, and it remains debated whether these scores reflect a comorbid depressive disorder or rather distress caused by tinnitus.

Methods:
To determine whether this elevated rate may partly result from symptom overlap between severe tinnitus and depression, the Major Depression Inventory (MDI) was administered to a cohort of 2693 patients with chronic tinnitus. Data were evaluated both categorically according to ICD-10 diagnostic criteria and dimensionally using total sum scores.

Results:
The categorical approach indicated a rate of 17.1%, whereas the dimensional assessment yielded a rate of 28.5%. To examine whether this discrepancy was specific to tinnitus or represented a methodological limitation of the MDI, a comparable analysis was conducted in patients with clinically diagnosed depression. This analysis also revealed a higher rate (86.4% vs. 69.7%) and greater severity under the dimensional framework. After lowering the threshold for core symptoms in the categorical approach, the rate estimates across evaluation systems aligned (Depression: 86.4% vs. 83.3%; Tinnitus: 28.5% vs. 27.3%).

Conclusion:
Core depressive symptoms frequently occur in tinnitus but appear to show greater temporal variability than in major depression. Differences in rates arise from both symptom overlap and methodological factors. Self-report scales have limitations, particularly with somatic or psychiatric comorbidity. Future studies should incorporate observer-rated scales or diagnostic interviews. Clinically, distinguishing depressive symptoms related to severe tinnitus from coexisting depression remains challenging.



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Details

DokumentenartArtikel
Titel eines Journals oder einer ZeitschriftJournal of Psychosomatic Research
Verlag:Elsevier
Band:207
Seitenbereich:S. 112679
Datum15 April 2026
InstitutionenMedizin > Lehrstuhl für Psychiatrie und Psychotherapie
Identifikationsnummer
WertTyp
10.1016/j.jpsychores.2026.112679DOI
Stichwörter / KeywordsTinnitus Tinnitus disorder Distress Depression Depressive symptoms Major depression Major Depression Inventory MDI Dimensional Categorical
Dewey-Dezimal-Klassifikation600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin
StatusVeröffentlicht
BegutachtetJa, diese Version wurde begutachtet
An der Universität Regensburg entstandenJa
URN der UB Regensburgurn:nbn:de:bvb:355-epub-793187
Dokumenten-ID79318

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