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Evaluation of a high-content screening fluorescence-based assay analyzing the pharmacological modulation of lipid homeostasis in human macrophages

Werner, Tobias and Liebisch, Gerhard and Grandl, Margot and Schmitz, Gerd (2006) Evaluation of a high-content screening fluorescence-based assay analyzing the pharmacological modulation of lipid homeostasis in human macrophages. Cytometry. Part A : the journal of the International Society for Analytical Cytology 69 (3), pp. 200-202.

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Other URL: http://dx.doi.org/10.1002/cyto.a.20237


Abstract

BACKGROUND: For understanding cholesterol and phospholipid efflux pathways there is a need for cellular fluorescence-based high-content screens (HCS) to investigated the cholesterol and phospholipid content in human macrophages. METHODS: Making use of fluorescence imaging based on HCS we have developed a tool to evaluate new agents that can act as inducers of cholesterol efflux. The fluorescence ...

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Item Type:Article
Date:March 2006
Institutions:Medicine > Lehrstuhl für Klinische Chemie und Laboratoriumsmedizin
Identification Number:
ValueType
16496419PubMed ID
10.1002/cyto.a.20237DOI
Keywords:high-content screening; fluorescence; lipid homeostasis
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Ute Lange
Deposited On:08 Feb 2007
Last Modified:13 Mar 2014 09:44
Item ID:1037
Owner Only: item control page
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