Resch, Markus and Banas, Bernhard and Endemann, Dierk and Mack, Matthias and Riegger, Günter A. J. and Gröne, Hermann-Josef and Krämer, Bernhard K. (2006) Exanthema and acute anuric renal failure. Clinical nephrology 65 (5), pp. 361-363.
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A 15-year-old girl with a history of Kawasaki disease was admitted to our nephrological department due to acute renal failure. Despite antibiotic therapy because of fever and the symptoms of a pharyngitis in the last few days, the girl showed persisting fever and developed arthralgias, an exanthema and a rising serum creatinine as well as anuria. A wide variety of differential diagnoses has to be thought of because of the history of the Kawasaki disease (symptoms like fever, pharyngitis, exanthema and arthralgia), i.e. hemolytic-uremic syndrome, vasculitis, ascending infection, postinfection glomerulonephritis. In consideration of etiologically unclear "rapidly progressive renal failure" with anuria and thrombocytopenia an immediate renal biopsy was done and revealed a severe drug induced acute interstitial nephritis. Due to this diagnosis we treated the patient with corticosteroids. Within 4 weeks serum creatinine declined to 1.8 mg/dl but did not normalize.
|Institutions:||Medicine > Lehrstuhl für Innere Medizin II|
|Keywords:||exanthema; acute anuric renal failure; drug-in duced acute interstitial nephritis|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Yes|
|Deposited On:||22 Mar 2007|
|Last Modified:||13 Mar 2014 09:50|