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The membrane-bound ectopeptidase CPM as a marker of macrophage maturation in vitro and in vivo

Rehli, M. and Krause, S. W. and Andreesen, Reinhard (2000) The membrane-bound ectopeptidase CPM as a marker of macrophage maturation in vitro and in vivo. Advances in experimental medicine and biology 477, pp. 205-16.

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Abstract

During terminal maturation of human blood monocytes into macrophages, a multitude of phenotypic and functional changes occurs: cells increase in size, they enhance their capacity for phagocytosis and tumor cytotoxicity but decrease their ability for T-lymphocyte stimulation. The pattern of secreted cytokines is shifted as is the profile of surface antigens. We recently identified carboxypeptidase ...

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Item Type:Article
Date:2000
Institutions:Medicine > Abteilung für Hämatologie und Internistische Onkologie
Identification Number:
ValueType
10849748PubMed ID
10.1007/0-306-46826-3_23DOI
Classification:
NotationType
AnimalsMESH
Antibodies, Monoclonal/immunologyMESH
Antigens, Differentiation/analysisMESH
Antigens, Surface/analysisMESH
Biological MarkersMESH
Cell DifferentiationMESH
Cell Membrane/enzymologyMESH
DNA, Complementary/geneticsMESH
Gene TargetingMESH
HumansMESH
Lymphocyte ActivationMESH
Macrophages/enzymologyMESH
Membrane Proteins/analysisMESH
Metalloendopeptidases/immunologyMESH
MiceMESH
Organ SpecificityMESH
T-Lymphocytes/immunologyMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:15 Apr 2010 05:18
Last Modified:15 Apr 2010 05:18
Item ID:14352
Owner Only: item control page
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