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Flow cytometric detection and quantitation of the epidermal growth factor receptor in comparison to Scatchard analysis in human bladder carcinoma cell lines

Brockhoff, G. and Hofstaedter, Ferdinand and Knuechel, R. (1994) Flow cytometric detection and quantitation of the epidermal growth factor receptor in comparison to Scatchard analysis in human bladder carcinoma cell lines. Cytometry 17 (1), pp. 75-83.

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Abstract

The epidermal growth factor receptor (EGFR) is considered a tumor-related marker with potential diagnostic and prognostic value. In order to assess the sensitivity of flow cytometry to detect EGFR and to quantify receptors objectively, two human bladder carcinoma cell lines with different urothelial differentiation, RT4 and J82, were grown in vitro, and their membrane EGFR content was measured by ...

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Item Type:Article
Date:1994
Additional information (public):Forts.:Cytometry / A; Cytometry / B
Institutions:Medicine > Lehrstuhl für Pathologie
Identification Number:
ValueType
8001460PubMed ID
10.1002/cyto.990170110DOI
Classification:
NotationType
Carcinoma, Papillary/pathologyMESH
Carcinoma, Transitional Cell/pathologyMESH
Cell DifferentiationMESH
Culture Media, Conditioned/chemistryMESH
DNA, Neoplasm/analysisMESH
Flow CytometryMESH
Fluorescent Antibody TechniqueMESH
Fluorescent DyesMESH
HumansMESH
KineticsMESH
MicrospheresMESH
Neoplasm Proteins/analysisMESH
PropidiumMESH
Protein BindingMESH
Receptor, Epidermal Growth Factor/analysisMESH
Sensitivity and SpecificityMESH
Tumor Cells, CulturedMESH
Tumor Markers, Biological/analysisMESH
Urinary Bladder Neoplasms/pathologyMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Unknown
Created at the University of Regensburg:Unknown
Owner: Gertraud Kellers
Deposited On:11 Jun 2010 07:43
Last Modified:11 Jun 2010 07:43
Item ID:15290
Owner Only: item control page
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