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Effect of meso- and dl-N,N'-dibutyl-alpha,alpha-bis(3-chloro-4-methoxyphenyl)ethylenediamine on the mammary tumor in the Sprague-Dawley rat induced by 7,12-dimethylbenz[alpha]anthracene (DMBA). 14. Cytostatic compounds

Schönenberger, Helmut and Griebl, G. and Adam, D. and Adam, A. (1971) Effect of meso- and dl-N,N'-dibutyl-alpha,alpha-bis(3-chloro-4-methoxyphenyl)ethylenediamine on the mammary tumor in the Sprague-Dawley rat induced by 7,12-dimethylbenz[alpha]anthracene (DMBA). 14. Cytostatic compounds. Arzneimittel-Forschung = Drug research 21 (12), pp. 2104-2106.

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Abstract

Following the production of meso-N,N'-dibutyl-alpha ,alpha '-bis(3-chloro-4-methoxyphenyl)ethylenediamine (I) [34608-86-1] and dl-N,N'-dibutyl-alpha ,alpha '-bis(3-chloro-4-methoxyphenyl)ethylenediamine (II) [27958-22-1] by the redn. of 3-chloro-4-methoxybenzylidenebutylamine with activated Al in alc., the compds. were tested for antimicrobial and antitumor activity. II inhibited ...

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Item Type:Article
Date:1971
Additional information (public):CAN 76:121694 1 Pharmacodynamics 27958-22-1; 34608-86-1 Role: BIOL (Biological study) (mammary gland neoplasm treatment by)
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Retired Professors > Prof. Schönenberger
Identification Number:
ValueType
1972:121694Other
Keywords:Mammary gland (neoplasm of, ethylenediamine deriv. in treatment of) Neoplasm (of mammary gland, ethylenediamine deriv. in treatment of) cytostatic benzanthracene tumor ethylenediamine cytostat
Subjects:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Petra Gürster
Deposited On:19 Nov 2010 09:18
Last Modified:19 Nov 2010 09:18
Item ID:18162
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