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Polysaccharide aus Nerium oleander: Struktur und biologische Aktivität [Polysaccharides from Nerium oleander: structure and biological activity]

Müller, B. M. and Rosskopf, F. and Paper, D. H. and Kraus, J. and Franz, Gerhard (1991) Polysaccharide aus Nerium oleander: Struktur und biologische Aktivität [Polysaccharides from Nerium oleander: structure and biological activity]. Die Pharmazie 46 (9), pp. 657-663.

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Abstract

A water extraction of crushed leaves of Nerium oleander yielded 2.3% of a crude polysaccharide. The main fraction (67%) represents a pectic polysaccharide mainly composed of galacturonic acid besides rhamnose, arabinose and galactose. The polysaccharide structure was characterized by NMR, mild acid- and pectinase treatment combined with GC-MS analyses. In vivo tests for a possible antitumor ...

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Item Type:Article
Date:1991
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Retired Professors > Prof. Franz
Identification Number:
ValueType
1798730PubMed ID
Classification:
NotationType
AnimalsMESH
Antineoplastic Agents, Phytogenic/pharmacologyMESH
Cell Survival/drug effectsMESH
FemaleMESH
HydrolysisMESH
Immunologic Factors/pharmacologyMESH
Limulus TestMESH
Lymphocytes/drug effectsMESH
Macrophages/drug effectsMESH
Magnetic Resonance SpectroscopyMESH
MaleMESH
MethylationMESH
MiceMESH
Mice, Inbred C3HMESH
Mitogens/pharmacologyMESH
Phagocytosis/drug effectsMESH
Plant Extracts/pharmacologyMESH
Plants, Medicinal/chemistryMESH
Polysaccharides/pharmacologyMESH
Protease Inhibitors/pharmacologyMESH
Structure-Activity RelationshipMESH
Tumor Cells, Cultured/drug effectsMESH
Subjects:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Gertraud Kellers
Deposited On:16 Nov 2011 09:19
Last Modified:16 Nov 2011 09:19
Item ID:22568
Owner Only: item control page
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