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LaPSvS1, a (1→3)-β-galactan sulfate and its effect on angiogenesis in vivo and in vitro

Bürgermeister, Jutta and Paper, Dietrich H. and Vogl, Horst and Linhardt, Robert J. and Franz, Gerhard (2002) LaPSvS1, a (1→3)-β-galactan sulfate and its effect on angiogenesis in vivo and in vitro. Carbohydrate research 337 (16), pp. 1459-1466.

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Abstract

LaPSvS1, a highly sulfated branched (1→3)-β-galactan was prepared from the arabino-galactan from Larix decidua Miller by partial hydrolysis and subsequent sulfation with SO3-pyridine in DMF. The molecular weight was analyzed by GPC and the sulfate content was determined by ion chromatography. LaPSvS1 exhibited good antiangiogenic and antiinflammatory effects in two different modifications of the ...

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Item Type:Article
Date:2002
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Retired Professors > Prof. Franz
Identification Number:
ValueType
12204607PubMed ID
Classification:
NotationType
Allantois/blood supplyMESH
Angiogenesis Inhibitors/pharmacologyMESH
AnimalsMESH
Anti-Inflammatory Agents/pharmacologyMESH
Arabinose/chemistryMESH
Chick EmbryoMESH
Chorion/blood supplyMESH
Dose-Response Relationship, DrugMESH
Fabaceae/chemistryMESH
Fibroblast Growth Factor 2/pharmacologyMESH
Galactans/pharmacologyMESH
Heparin/metabolismMESH
Neovascularization, Physiologic/drug effectsMESH
Plants, MedicinalMESH
Sodium Dodecyl Sulfate/pharmacologyMESH
Spectrometry, FluorescenceMESH
Sulfates/pharmacologyMESH
Time FactorsMESH
Subjects:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Gertraud Kellers
Deposited On:21 Nov 2011 10:29
Last Modified:29 Nov 2011 06:59
Item ID:22619
Owner Only: item control page
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