Franz, Gerhard and Feuerstein, U. (1997) Chemical stability of some model polysaccharides. Macromolecular Symposia 120, pp. 169-181.
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A series of different Polysaccharides with actual or potential medicinal or industrial utilization such as linear fructans of the inuline type, branched fungal ß-1.3, 1.6-glucans, galactomannans of the guar type, acidic polysaccharides such as alginates, pectins were submitted to experimental stress- and non stress conditions. The resistance to humidity, thermal degradation, pH influence and microbial decomposition was studied by measuring the relative viscosity, reduction in DP values, degradation of specific conformations and glycosidic linkages.
It could be clearly shown that most polysaccharides are stable at room temerature in a dry environment. At increased temperature even in the absence of water, polymer decomposition was documented. Polysaccharide solutions, when stored under thermal stress (40°, 60°, 80°C), showed structure dependent rapid progress in degradation of primary and secondary structures. The kinetics of these decompositions were measured over prolonged periods in order to give a practical background for the utilization of such polymers in pharmaceuticals, cosmetics and food products.
|Institutions:||Chemistry and Pharmacy > Institute of Pharmacy > Retired Professors > Prof. Franz|
|Subjects:||500 Science > 540 Chemistry & allied sciences|
|Created at the University of Regensburg:||Unknown|
|Deposited On:||30 Nov 2011 09:46|
|Last Modified:||30 Nov 2011 09:46|
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