Gleich, Otto and Bielenberg, Katrin and Strutz, Jürgen (1995) Sound induced expression of c-Fos in GABA positive neurones of the gerbil cochlear nucleus. NeuroReport 7 (1), pp. 29-32.
To characterize c-Fos-expressing neurones in more detail, a double labelling technique was developed to simultaneously demonstrate the presence of GABA-like and c-Fos-like immunoreactivity in cryostat sections of the gerbil cochlear nucleus. The animals were exposed to a wide-band noise stimulus for the induction of c-Fos expression. The distribution of c-Fos-positive cells and GABA-positive somata was consistent with previous reports. Our double labelling approach revealed the presence of GABA-positive cells that showed c-Fos expression after noise stimulation. One interpretation of this finding is that a prolonged acoustic exposure induces long term changes in inhibitory interneurones to adjust the output of the cochlear nucleus.
|Date:||29 December 1995|
|Institutions:||Medicine > Lehrstuhl für Hals-Nasen-Ohren-Heilkunde|
|Subjects:||500 Science > 590 Zoological sciences|
600 Technology > 610 Medical sciences Medicine
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Yes|
|Deposited On:||09 Sep 2008 14:28|
|Last Modified:||20 Jul 2011 21:20|