Alterations in intestinal fatty acid metabolism in inflammatory bowel disease

DOI to cite this document:: 10.5283/epub.1004

Heimerl, Susanne ; Moehle, Christoph ; Zahn, Alexandra ; Boettcher, Alfred ; Stremmel, Wolfgang ; Langmann, Thomas ; Schmitz, Gerd

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Date of publication of this fulltext: 05 Aug 2009 13:24

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Abstract

Inflammatory bowel disease (IBD) constitutes a severe intestinal disorder in developed countries with increasing incidence worldwide. Upcoming evidence indicates an important role of intestinal epithelial barrier function in the development of IBD. Fatty acids exert nutritional and protective effects on enterocytes, serve as activators of transcription and constitute precursors of inflammatory ...